CN107541528A - The Saccharomyces veronae zymotic fluids of sprouted unpolished rice - Google Patents
The Saccharomyces veronae zymotic fluids of sprouted unpolished rice Download PDFInfo
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- CN107541528A CN107541528A CN201710204042.0A CN201710204042A CN107541528A CN 107541528 A CN107541528 A CN 107541528A CN 201710204042 A CN201710204042 A CN 201710204042A CN 107541528 A CN107541528 A CN 107541528A
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- rice
- extract
- zymotic fluid
- enriched
- aminobutyric acid
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Abstract
The problem of the present invention is the manufacture method for providing the skin preparations for extenal use for the rice fermentation liquid for having coordinated that amino acid content is more, moisture retention is excellent and gamma aminobutyric acid is enriched with.Specifically, it is to provide the rice that gamma aminobutyric acid is enriched with the Saccharomyces veronae zymotic fluids to ferment and the skin preparations for extenal use for having coordinated the zymotic fluid.
Description
Technical field
The present invention relates to a kind of rice Saccharomyces for having coordinated and being enriched with γ-aminobutyric acid
The skin preparations for extenal use for the zymotic fluid that veronae is fermented.
Background technology
Propose the technology (patent document 1 that the bent material for acting on sprouted rice extract will be made to be used for cosmetics:Japan
Unexamined Patent 7-10733 publications).Propose the technology (patent document 2 that the fermentate of sprouted unpolished rice chaff is matched with to cosmetic preparation:
Japanese Unexamined Patent Publication 2007-131578 publications).
Patent document 1:Japanese Unexamined Patent Publication 7-10733 publications
Patent document 2:Japanese Unexamined Patent Publication 2007-131578 publications
The content of the invention
The problem of the present invention is to provide that amino acid content is more, moisture retention is excellent and γ-aminobutyric acid is enriched with is big
Rice zymotic fluid and coordinated the zymotic fluid skin preparations for extenal use manufacture method.
A kind of 1. zymotic fluid, it is characterised in that the rice Saccharomyces for being enriched with γ-aminobutyric acid
Veronae is fermented.
2. a kind of manufacture method of zymotic fluid, it is characterised in that the rice for being enriched with γ-aminobutyric acid is used
Saccharomyces veronae are fermented.
3. a kind of skin preparations for extenal use, it is characterised in that coordinated the rice for being enriched with γ-aminobutyric acid to use
The zymotic fluid that Saccharomyces veronae are fermented.
4. a kind of manufacture method of skin preparations for extenal use, it is characterised in that coordinated the rice for being enriched with γ-aminobutyric acid to use
The zymotic fluid that Saccharomyces veronae are fermented.
The zymotic fluid of the present invention is to enter the rice that γ-aminobutyric acid is enriched with Saccharomyces veronae
Row fermentation forms, and amino acid content is more, moisture retention is excellent.The skin parent of the skin preparations for extenal use of the invention of the zymotic fluid is coordinated
It is excellent with power, it is also excellent without smell, the continuation of moistening effect.
Brief description of the drawings
The purified water for 1, the 2- pentanediols that Fig. 1 expressions will respectively with the addition of 5%, rice fermentation liquid, fermentation by saccharomyces cerevisiae liquid, hair
Bud rice fermentation liquid is as sample, in the difference of the front and rear cuticlar water component of skin coating.
Fig. 2 represent purified water, rice fermentation liquid, sprouted rice zymotic fluid before coating after from the percutaneous water loss amount of cuticula
Difference.
Fig. 3 is the purified water of contact angle determination, rice fermentation liquid, fermentation by saccharomyces cerevisiae liquid, the drop of sprouted rice zymotic fluid
Photo.
Fig. 4 represents the amino acid content of rice fermentation liquid and sprouted rice zymotic fluid.
Embodiment
It is known to increase γ-aminobutyric acid during brown rice germination.γ-aminobutyric acid used in the present invention is enriched with big
Rice refers to the rice of commonly referred to as sprouted unpolished rice, according to the physiological action of rice, is enriched with for γ-aminobutyric acid big
Rice.
The manufacture method for the rice being enriched with as γ-aminobutyric acid, such as method can be listed below:By brown rice 5
~50 DEG C, dipping appropriate time makes its germination in preferably 20~40 DEG C of warm water, and the brown rice of the germination at ambient pressure or is added
Depress boiling.
Further, since the germinating method impregnated in water, which has, occurs nutrient loss, the worry of bacterium breeding, so or not
Impregnated in water and the method by slowly adding water to make it germinate.γ-aminobutyric acid can be enriched with by the following method:With
0.5~2.0 mass %/h's adds water speed to carry out slowly adding water, makes the water that moisture is adjusted to 10~15% brown rice in advance
20~30% scope (adding water conservancy project sequence) is divided into, the brown rice then put into tank to that 2~10 are carried out under aeration condition is small
When quenched (mediation) (quenched process), after making brown rice germination (germination process), (steamed with 100 DEG C of vapour cookings 5~30 minutes
Boiling procedure), further it is aerated and dries (drying process).
And then the γ-aminobutyric acid of rice can be also enriched with by the following method:Entered with 0.5~2.0 mass %/h's plus water speed
Row plus water, make moisture is adjusted into the moisture of 10~15% brown rice until turning into 16~20 mass % (adding water conservancy project sequence) in advance,
Quenched (mediation) (quenched germination process) is further carried out under aeration condition, after making brown rice germination, carrying out heating setting makes
The center product temperature of brown rice turns into 40~60 DEG C (heating processes), carries out boiling (cooking process) with 98~100 DEG C of steam, enters one
Step is dried (drying process).It can shorten drying time using during this method.
Biological action can be produced to brown rice by above-mentioned manufacture method, so as to which γ-aminobutyric acid is enriched with.100g brown rice
In γ-aminobutyric acid amount be usually 1~9mg, be increased to 10~35mg when being enriched γ-aminobutyric acid.
The rice that γ-aminobutyric acid is enriched with crushes, relative to the γ more than 10 parts by weight, below 100 parts by weight-
The rice that aminobutyric acid is enriched with adds more than 100 parts by weight, the water below 10000 parts by weight, in 110 DEG C of heat sterilizations 5
Minute.Thereafter, add more than 1.0 parts by weight, after the amylase below 10 parts by weight, add more than 1.0 parts by weight, 10 parts by weight
Following Saccharomyces veronae ferment more than 16 hours, less than 48 hours.And then in 110 DEG C of 5 points of heating sterilizations
Clock stops fermentation, and after the removal residue that 5 DEG C carry out 3 days, resulting fermentate is carried out into membrane filtration so as to be fermented
Liquid.
Saccharomyces veronae used in the fermentation of the present invention is do not produce the yeast that ethanol produces lactic acid, also
Known generation ceramide.Saccharomyces veronae are the wild yeasts separated from resin, and speciality is lactic acid producing energy
Power is high.Saccharomyces veronae propagation thermophilic is 20~35 DEG C, preferably 30 DEG C or so, can be in the temperature close to room temperature
Degree is lower to ferment.Other generally known Yeast Phase ratios, Saccharomyces veronae fermentation character are excellent with saccharomyces cerevisiae etc.
It is different.And then due to compared with saccharomyces cerevisiae, being wrapped with the zymotic fluid of the sprouted unpolished rice of Saccharomyces veronae fermentations
The evaporation residual component contained can include qdx or so, so can obtain the excellent zymotic fluid of moisture retention, skin affinity.
The zymotic fluid of the present invention can also use directly as skin preparations for extenal use, in order that it possesses moisture retention, antibiotic property, also
The polyalcohol or phenoxetol, zinc epoxide glycerine of 1,3-BDO, 1,2- pentanediols, propane diols, DPG etc. can be added
Etc. (Octoxyglycerin) it is used as skin preparations for extenal use.In addition, be alternatively arranged as moisturizing ingredient be matched with toner, emulsion, frost,
The Hydra skin preparations for extenal use of gel etc..The use level for being matched with the zymotic fluid of the present invention of skin preparations for extenal use is as follows:It is preferred from
The evaporation residual component of zymotic fluid with synthesizing more than 0.05 mass %, particularly preferred more than 0.05 mass %, 6.0 mass % with
Under.
The present invention skin preparations for extenal use include cosmetic preparation, medicine part outer article, pharmaceuticals, can be made into toner, emulsion, frost,
Solution shape, emulsion shape, the Macromolecule glue preparation of gel etc..In addition, can also be blister preparation, more stratiform preparations, spraying
Preparation, the Formulation for being impregnated in non-woven fabrics etc. or gel mask preparation.
According to purpose, can also contain as any condition in the skin preparations for extenal use of the present invention NMF, surfactant,
Tackifier, antiinflammatory, vitamins, antioxidant, blood flow ameliorant, wound healing agent, antibacterial material, skin activating agent, often
The effective component of controlling agent in bacterium, active oxygen eliminating agent, whitening agent etc..
As effective component, as long as it can be used in the past in pharmaceuticals, medicine part outer article, cosmetics, hygienic material etc.
And the material that can be dissolved or disperse in water, then it can be not particularly limited to use.Specifically, Angelica Keiskei extraction can be enumerated
Thing, Avocado extract, bastard silk ball leaf extract, hollyhock genus plants extract, Arnica extract, apricot extract, almond carry
Take thing, anise extract, Turmeric P.E, oolong tea extract, Echinacea leaf extract, Baical Skullcap root P.E, cork tree extract,
Fructus Hordei Vulgaris extract, green water cress extract, orange extract, seawater dried object, elastin hydrolysis, hydrolyzed wheat powder, hydrolyzed-silk,
Camomile extract, carrot extract, oriental wormwood parthenium extract, licorice, roselle extract, Kiwi extract, gold
Chicken receives extract, Fructus Cucumidis sativi extract, guanosine, Indocalamus leaf extract, Walnut extract, grapefruit extract, clematis extract, ferment
Female extract, burdock extract, comfrey extract, collagen, Bilberry fruit P.E, bupleurum extract, umbilical cord extract solution, mouse
Tail grass extract, Saponaria officinalis extract, thin bamboo extract, haw thorn extract, Shitake Mushroom P.E, glutinous rehmannia extract, alkanet carry
Take thing, lime tree extract, palmate meadowsweet extract, calamus root extract, white birch extract, Horsetail P.E, Honegsukle flower P.E,
Ivy extract, fructus crataegi cuneatae extract, golden elder extract, Yarrow extract, foreign mint extract, high mallow carry
Take thing, swertia japonica Makino extract, Fructus Jujubae extract, thyme extract, Flos Caryophylli extract, cogongrass extract, dried orange peel extracts,
Extract from Orange Peel, heartleaf houttuynia extract, tomato extract, natto extract, carrot extract, multiflora rose extract, the rose of Sharon carry
Take thing, ophiopogon japonicus extract, caraway extract, honey, pellitory (Parietaria) extract, Isodon Japonica Hara extraction
Thing, Bisabolol terpene alcohol, coltsfoot extract, tussilago stem extraction, tuckahoe extracts, Ruscus extract, grape extract, honeybee
Glue, Fructus Luffae extract, Peppermint essential oil extract, bodhi tree extract, lupulus extract, loose extract, European horse-chestnut carry
Take thing, Alocasia amazonica extract, soapberry extract, peach extract, corn flower extract, Eucalyptus globulus Labill.extract, grapefruit abstract, Chinese mugwort
Parthenium extract, Herba Lysimachiae foenumgraeci extract, apple extract, Caulis et Folium Lactucae sativae extract, lemon extract, Chinese milk vetch extract, rose extraction
Thing, Rosmarinus officinalis extract, Rome camomile extract, royal jelly extract etc..
In addition, it can also enumerate amino acid, urea, pyrrolidone sodium carboxylate, glycine betaine, whey, trimethylglycine etc.
NMF;The oil components of sphingolipid, ceramide, cholesterol, cholesterol derivative, phosphatide etc.;ε-aminocaproic acid, radix glycyrrhizae
The antiinflammatory of acid, β-enoxolone, lysozyme chloride, guaiazulene, hydrocortisone etc.;Vitamin A, B2, B6, D are E, general
The vitamins of sour calcium, biotin, niacinamide etc.;Tocopherol, carotenoid, flavonoids, tannin, lignanoid, saponin(e etc. resist
Oxidant;The blood flow ameliorant of gamma oryzanol, vitamin e derivative etc.;The trauma care of retinol, retinol derivatives etc.
Agent;The life of DNA, sodium chondroitin sulfate, collagen, elastin laminin, chitin, chitosan, hydrolysis egg shell membrane etc.
Object macromolecule;The active component of allantoin, diisopropylamine dichloroacetate, 4- aminomethyl cyclohexanecarboxylic acid etc.;Cepharanthine, capsicum
Tincture, Hinokitiol, iodate garlic P.E, puridoxine hydrochloride, dl- alpha-tocopherols, acetic acid dl- alpha-tocopherols, nicotinic acid, nicotinic acid derive
Thing, D-pantothenyl aleohol, DL-Pantyl Ethyl Ether acetic acid esters, biotin, allantoin, isopropyl methyl phenol, estradiol, ethinyloestradiol, Kapp
Oronain, benzalkonium chloride, bagodryl hydrochloride, Takanal, camphor, salicylic acid, n-nonanoic acid chinese cymbidium acid amides (Nonylic acid
Vanillylamide), n-nonanoic acid chinese cymbidium acid amides (Nonanoic acid vanillylamide), piroctone olamine, 15
Alkanoic acid monoglyceride, single nitroguaiacol, resorcinol, γ-aminobutyric acid, benzethonium chloride, mexiletine hydrochloride, auxin,
Estrogen, cantharidin, Ciclosporin A, hydrocortisone, polyoxyethylene sorbitan monostearate etc..
Embodiment
[manufacture for the rice that γ-aminobutyric acid is enriched with]
Brown rice (dream of star) is produced using Hokkaido that moisture is adjusted to 14% or so in advance, carries out wherein slowly plus water makes
Moisture turns into 20~30% scope.In order to not produce grain of rice cracking, this slowly adds water process gently to carry out.It is specific and
Speech, while brown rice is stirred in horizontal shape cylinder, while the side do not dripped with water by being arranged at two liquid spray nozzles on the inside of cylinder
Formula carries out plus water.Water temperature is the temperature of running water, does not carry out pH adjustment.Spraying from nozzle is with water not from the side of brown rice drippage
Formula is attached to the surface of brown rice as vaporific water droplet.By stir brown rice while make its contact the vaporific water droplet so as to
Equably plus water.As the water for adding water, running water is used.Add to be transferred in tank after the completion of water and carry out quenched (mediation).Should
Environmental optima temperature during mediation is 16~24 DEG C, and ambient atmos are imported into tank and are taken a breath.A series of process is at 20 DEG C
The progress at room temperature of left and right, steam treatment is carried out to brown rice after the completion of mediation.Steam treatment is used by using continuous steamed rice machine
2kg/h, 100 DEG C of vapour cooking stipulated time are carried out.And then by the brown rice after the completion of the boiling normal temperature wind pushing temperature
Under be dried, so as to obtain the rice that the γ-aminobutyric acid of moisture about 15% is enriched with.γ-aminobutyric acid is enriched with
The concentration of γ-aminobutyric acid that is included of rice be 13mg/100g.
[manufacture of zymotic fluid]
The rice that resulting γ-aminobutyric acid is enriched with is crushed, and richness is obtained relative to the γ-aminobutyric acid of 10 parts by weight
The rice of collection adds the water of 1000 parts by weight, and in 110 DEG C of heat sterilizations 5 minutes.Thereafter, the amylase of 1.0 parts by weight is added
30 DEG C are heated up to the Saccharomyces veronae of 1.0 parts by weight, it is fermented 20 hours.Thereafter, in 110 DEG C of progress
Heating sterilization stops fermentation.Resulting fermentate is filtered so as to obtain zymotic fluid (hereinafter referred to as sprouted rice zymotic fluid.).
The rice for replacing γ-aminobutyric acid to be enriched with using pure white rice similarly obtains zymotic fluid, and (hereinafter referred to as rice is sent out
Zymotic fluid.), so as to as a comparison case.
In addition, the rice fermentation for being enriched with γ-aminobutyric acid using saccharomyces cerevisiae (is hereinafter referred to as made so as to obtain zymotic fluid
Brewer yeast zymotic fluid.), so as to as a comparison case.
[moisture retention experiment 1]
By the purified water for 1, the 2- pentanediols that respectively with the addition of 5%, rice fermentation liquid, fermentation by saccharomyces cerevisiae liquid, sprouted rice fermentation
Liquid is as sample coating in the amount of moisture of skin, accordingly contrast cuticula.And due to rice fermentation liquid, fermentation by saccharomyces cerevisiae liquid,
The evaporation residual component (amino acid etc.) of sprouted rice zymotic fluid is 0.3 mass %, 0.25 mass %, 0.59 mass %, so
The dilution of sprouted rice zymotic fluid purified water is made into amount of the evaporation residual component as half.
First, adapted to 10 minutes after cleaning Medial upper arm portion, with the measure device (strain of epidermis cuticlar water component before sample is coated with
Formula commercial firm YAYOI systems, device name:SKICON-200EX the amount of moisture of Medial upper arm portion cuticula) is determined.Thereafter, in measure position
Put that 0.03g samples are added dropwise and are coated with and be extended to 2cm × 2cm, amount of moisture is determined after 15 minutes.Before sample coating with the water after coating
The difference of component is as shown in Figure 1.
With rice fermentation liquid, fermentation by saccharomyces cerevisiae liquid phase ratio, sprouted rice zymotic fluid shows significant moisture retention.In addition, can
Confirm that it promptly soaks cuticula.
[moisture retention experiment 2]
(do not adjusted by being coated with purified water, rice fermentation liquid, sprouted rice zymotic fluid used in above-mentioned [moisture retention experiment 1]
Evaporation residual component) contrast the percutaneous water loss amount from cuticula.With above-mentioned [moisture retention experiment 1] equally, upper arm is cleaned
Adapted to 10 minutes behind inside portion, with portable moisture meter (Delphin Technology company systems, device before sample is coated with
Name:VapoMeter the percutaneous water loss amount in Medial upper arm portion) is determined.Thereafter, 0.03g samples and apply locating to be added dropwise
Cloth is extended to 2cm × 2cm, and the number of dropouts of moisture is determined after 5 minutes.Before sample coating with the percutaneous water loss amount after coating
Difference is as shown in Figure 2.
Prompt the water loss inhibition of sprouted rice zymotic fluid good.
[experiment of skin affinity]
Contrast sample (purified water, rice fermentation liquid, fermentation by saccharomyces cerevisiae liquid, the sprouted rice fermentation of above-mentioned [moisture retention experiment 1]
Liquid) to the affinity of skin.
Instrument uses portable contact angle instrument (consonance Surface Science Co. Ltd. system, device name:PCA-1).Sample is filled in
0.7mL injection tubes, and in 1 μ L of the dropwise addition of Medial upper arm portion 1 time sample, be measured with sessile drop method.1000ms is determined with n=5
Contact angle C.A. (°), try to achieve average value with the method for θ/2.As a result it is as shown in Figure 3.
The contact angle for prompting the 1000ms of purified water is 95.3 °, and rice fermentation liquid is 76.3 °, and fermentation by saccharomyces cerevisiae liquid is
76.9 °, in contrast, the 1000ms of sprouted rice zymotic fluid contact angle is 72.9 °, the instantaneous liquid for dripping to skin is just opened up
Open.Sprouted rice zymotic fluid shows significant skin affinity effect.
[sensory evaluation 1]
Sent out by 6 professional judging panels respectively with the addition of the purified waters of 5% 1,2- pentanediols, fermentation by saccharomyces cerevisiae liquid, sprouted rice
The pliability of skin is evaluated after the smell of zymotic fluid, the continuation of smell, affinity, fusion.
And the evaporation residual component (amino acid etc.) of fermentation by saccharomyces cerevisiae liquid, sprouted rice zymotic fluid is 0.25 mass %, 0.59
Quality %.
The metewand of sensory evaluation 1 and sensory evaluation 2 is as shown below.
Smell
5 is odorless, 4 pay no attention to, it is 3 acceptable, 2 slightly take notice of, be 1 smelly
The continuation of smell
5 without, 4 disappear immediately, 3 general, 2 slightly residual, 1 offending smells continue
Affinity
5 is good, 4 slightly good, 3 general, 2 slightly worse, 1 poor
The pliability of skin after fusion
5 is soft, there is abrasive feel 4 slightly soft, 3 general, 2 slightly abrasive feel, 1
The continuation of moisturizing after fusion (after 30 minutes)
5 continue, 4 slightly continue, it is 3 general, 2 do not continue, 1 has abrasive feel
Respectively:More than 4 judging panel's evaluations 4 or 5, then be zero;Less than 3 evaluation less than 4 or 5 and 3 evaluate 1 or 2, then for
△;More than 4 evaluation 1 or 2, then for ×.As a result it is as shown in table 1.
Table 1
Sample A | Sample B | Sample C | |
Purified water | 95% | ||
Fermentation by saccharomyces cerevisiae liquid | 95% | ||
Sprouted rice zymotic fluid | 95% | ||
1,2- pentanediol | 5% | 5% | 5% |
Smell | ○ | × | ○ |
The continuation of smell | ○ | × | ○ |
Affinity | × | △ | ○ |
The pliability of skin after fusion | × | △ | ○ |
As shown in table 1, on smell, the atomic weak smell of sprouted rice zymotic fluid is blended in after skin rapidly after coating
Ground disappears, in contrast, fermentation by saccharomyces cerevisiae liquid smell after being just coated with is smelly, more than 15 minutes offending smells after coating
Also continuing, be undesirable result.For the skin after fusion, fermentation by saccharomyces cerevisiae liquid somewhat remains abrasive feel, hair
Bud rice fermentation liquid is soft sense of touch.
[sensory evaluation 2]
The evaporation residual component of the sprouted rice zymotic fluid to be fermented with Saccharomyces veronae is adjusted from 0.1 mass %
It is whole when being 0.5%, to its smell and affinity, merge after the continuation (after 30 minutes) of moisturizing carry out sensory evaluation.
Now, the evaporation residual component 5.58 mass % to be fermented with Saccharomyces veronae sprouted rice is fermented
Liquid adjusts residual component with purified water, evaporation residual component is turned into 0.1 mass %, 0.2 mass %, 0.5 mass %.As a result
As shown in table 2.
Table 2
As shown in table 2, following evaluation has been obtained with the Saccharomyces veronae sprouted rice zymotic fluids to ferment:As
The concentration that residual component is more than 0.1% is evaporated, skin affinity is good.
[amino acid analysis]
Precise acquisition about 4g rice fermentations liquid and sprouted rice zymotic fluid, are 5mL with 0.1N hydrochloric acid solution constant volumes.The liquid is used
The liquid of 0.45 μm of film filter filtering is as sample solution.In addition, separately it will suitably dilute amino acid with 0.02N hydrochloric acid solutions
The standard items and liquid filtered by the use of 0.45 μm of film filter is used as standard liquid.Measure passes through effective amino-acid analyzer (strain formula
New and high technology section of Hitachi of commercial firm length of schooling, device name:L-8900 types) carry out.As a result it is as shown in Figure 4.
Understand compared with the zymotic fluid of rice, the amino acid content of sprouted rice zymotic fluid is more.Think in sprouted rice zymotic fluid
Amino acid be that sprouted rice zymotic fluid moisture retention high one will be because mostly.In addition, amino acid is advantageous to fermentation process more.
The toner of prescription example 1
1. sprouted rice zymotic fluid (evaporation residual component 0.2 mass %) 94.5%
2. glycerine 5.0%
3. phenoxetol 0.5%
1~3 is stirred so as to obtain toner.
The thick toner of prescription example 2
4 are added in 3 and makes it scattered.5 are dissolved with 6 part, remaining composition is added and mixes.
The beauty-care gel of prescription example 3
6 are made to be scattered in 2 (dispersions).5 are mixed with 7 (mixture).Dissolve remaining composition and slowly addition is scattered wherein
Thing makes its dissolving, is slowly added into mixture thereafter and is stirred with homogenizer.
Claims (4)
1. a kind of zymotic fluid, it is characterised in that by the rice that γ-aminobutyric acid is enriched with Saccharomyc es
Veronae is fermented.
2. a kind of manufacture method of zymotic fluid, it is characterised in that the rice for being enriched with γ-aminobutyric acid is used
Saccharomyces veronae are fermented.
3. a kind of skin preparations for extenal use, it is characterised in that coordinated the rice for being enriched with γ-aminobutyric acid to use
The zymotic fluid that Saccharomyces veronae are fermented.
4. a kind of manufacture method of skin preparations for extenal use, it is characterised in that coordinated the rice for being enriched with γ-aminobutyric acid to use
The zymotic fluid that Saccharomyces veronae are fermented.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2016127214A JP6662726B2 (en) | 2016-06-28 | 2016-06-28 | Germinated brown rice Saccharomyces verona fermented liquid |
JP2016-127214 | 2016-06-28 |
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CN107541528A true CN107541528A (en) | 2018-01-05 |
CN107541528B CN107541528B (en) | 2022-09-23 |
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CN201710204042.0A Active CN107541528B (en) | 2016-06-28 | 2017-03-30 | Saccharomyces veronae fermentation broth of germinated brown rice |
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JP (1) | JP6662726B2 (en) |
CN (1) | CN107541528B (en) |
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JP7094841B2 (en) * | 2018-09-06 | 2022-07-04 | 株式会社ファンケル | Fermented liquid of giant germ rice brown rice and an external skin preparation containing this fermented liquid |
JP7123706B2 (en) * | 2018-09-06 | 2022-08-23 | 株式会社ファンケル | Skin external preparation containing fermented liquid of giant germ brown rice and tranexamic acids |
JP2020050620A (en) * | 2018-09-27 | 2020-04-02 | 株式会社ファンケル | Skin external composition |
JP2021088524A (en) * | 2019-12-04 | 2021-06-10 | 株式会社Ftc | Liposome composition, skin external preparation containing the same, and method for producing liposome composition |
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- 2016-06-28 JP JP2016127214A patent/JP6662726B2/en active Active
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2017
- 2017-03-30 CN CN201710204042.0A patent/CN107541528B/en active Active
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JP2002253198A (en) * | 2001-02-28 | 2002-09-10 | Nakano Shuzo Kk | Sake and method for producing the same |
CN1960643A (en) * | 2004-05-14 | 2007-05-09 | 株式会社芳珂 | Germinating brown rice |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN114703074A (en) * | 2022-03-25 | 2022-07-05 | 华熙生物科技股份有限公司 | Saccharomyces cerevisiae and application thereof in preparing brown rice fermentation filtrate for cosmetics |
CN114703074B (en) * | 2022-03-25 | 2023-09-19 | 华熙生物科技股份有限公司 | Saccharomyces cerevisiae and application thereof in preparing brown rice fermentation filtrate for cosmetics |
Also Published As
Publication number | Publication date |
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TWI753901B (en) | 2022-02-01 |
TW201800580A (en) | 2018-01-01 |
JP2018002607A (en) | 2018-01-11 |
HK1245335A1 (en) | 2018-08-24 |
CN107541528B (en) | 2022-09-23 |
JP6662726B2 (en) | 2020-03-11 |
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