CN107494938A - A kind of Chinese herbal medicine mixed feed for improving beef cattle immunity and preparation method thereof - Google Patents
A kind of Chinese herbal medicine mixed feed for improving beef cattle immunity and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
- A23K10/37—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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Abstract
The present invention relates to a kind of Chinese herbal medicine mixed feed for improving beef cattle immunity and preparation method thereof, it is made up of the raw material of following parts by weight：30~60 parts of corn, 5~15 parts of dregs of beans, 10~20 parts of wheat bran, 5~15 parts of cottonseed cake, 1~5 part of bone meal, 15~45 parts of Chinese herb feed additive, 0.5~3.5 part of salt, 0.1~1 part of premix material additive, wherein, Chinese herb feed additive is made up of the raw material of following weight parts：30~60 parts of feed mulberry, anistree 0.5~3.5 part, 1~6 part of the red sage root, 1~6 part of ginger, 1~6 part of garlic, 1~6 part of the bark of eucommia, 1~6 part of dandelion.The various nutritional ingredient reasonable mixture ratios of Chinese herbal medicine mixed feed of the present invention, production cost is relatively low, for beef cattle feeding, feed intake, disease-resistant growth-promoting, enhancing immunity of organisms and the effect for improving oxidation resistance can be effectively improved, the problems such as so as to overcome nutritional ingredient shortage, nutrient content deficiency, drug resistance and environmental pollution in the prior art, be a kind of mixed feed of green natural.
Description
Technical field
The invention belongs to field of feed, and in particular to it is a kind of improve beef cattle immunity Chinese herbal medicine mixed feed and its
Preparation method.
Background technology
Beef is one of meat product of Chinese's consumption, and its sales volume is only second to pork.Beef nutritive value is high, containing rich
The compositions such as rich protein, vitamin B complex, nicotinic acid, calcium, phosphorus, iron, cholesterine, have and improve immunity of organisms, tonifying spleen and stomach, benefit
Gas disk, the effect of strengthening the bones and muscles.Secondly as beef protein content is high, fat content is relatively low, its delicious flavour, liked by people.
With the development of economy and society, people are increasing for the demand of beef and its product, due to beef cattle easily ill, the phase is cultivated
Long, feed cost is high, and steer ration enterprise promotes its growth often through to materials such as beef cattle injection hormone, antibiotic, prevents and treats
Disease.However, the material such as antibiotic easily remains in the product, easily make one to produce allergic reaction, be poisoned, even result in the mankind
The change of DNA structure, simultaneously as long-term low dose uses such material, easy Induction of bacterial produces drug resistance.Therefore, promote
It is very necessary using green, the antibiotic of safety and synthetic drug substitute products.
The content of the invention
It is an object of the present invention in view of the shortcomings of the prior art, there is provided a kind of Chinese herbal medicine for improving beef cattle immunity is answered
Feed and preparation method thereof is closed, the various nutritional ingredient reasonable mixture ratios of the Chinese herbal medicine mixed feed, production cost is relatively low, for beef cattle
Raising, feed intake, disease-resistant growth-promoting, enhancing immunity of organisms and the effect for improving oxidation resistance can be effectively improved, so as to overcome
It is a kind of answering for green natural in the prior art the problems such as nutritional ingredient shortage, nutrient content deficiency, drug resistance and environmental pollution
Close feed.
The present invention is achieved through the following technical solutions：
A kind of Chinese herbal medicine mixed feed for improving beef cattle immunity, include the raw material of following weight parts：Corn 30~60
Part, 5~15 parts of dregs of beans, 10~20 parts of wheat bran, 5~15 parts of cottonseed cake, 1~5 part of bone meal, 15~45 parts of Chinese herb feed additive, food
0.5~3.5 part of salt, 0.1~1 part of premix material additive；
Wherein, the Chinese herb feed additive is made up of the raw material of following weight parts：30~60 parts of feed mulberry, anise 0.5~
3.5 parts, 1~6 part of the red sage root, 1~6 part of ginger, 1~6 part of garlic, 1~6 part of the bark of eucommia, 1~6 part of dandelion.
Preferably, a kind of Chinese herbal medicine mixed feed for improving beef cattle immunity, the raw material of following weight parts are included：Corn
40~50 parts, 7~12 parts of dregs of beans, 12~17 parts of wheat bran, 7~12 parts of cottonseed cake, 1~5 part of bone meal, Chinese herb feed additive 20~40
Part, 1~2 part of salt, 0.3~0.8 part of premix material additive；
Wherein, the Chinese herb feed additive is made up of the raw material of following weight parts：40~50 parts of feed mulberry, anise 0.5~
2.5 parts, 1~4 part of the red sage root, 1~4 part of ginger, 1~4 part of garlic, 1~4 part of the bark of eucommia, 1~4 part of dandelion.
Preferably, a kind of Chinese herbal medicine mixed feed for improving beef cattle immunity, the raw material of following weight parts are included：Corn
47 parts, 10 parts of dregs of beans, 15 parts of wheat bran, 10 parts of cottonseed cake, 4 parts of bone meal, 35 parts of Chinese herb feed additive, 1.5 parts of salt, premix adds
Add 0.5 part of agent；
Wherein, the Chinese herb feed additive is made up of the raw material of following weight parts：45 parts of feed mulberry, anistree 1 part, the red sage root 3
Part, 3 parts of ginger, 3 parts of garlic, 3 parts of the bark of eucommia, 3 parts of dandelion.
Preferably, a kind of Chinese herbal medicine mixed feed for improving beef cattle immunity, the premix material additive are：Vitamin A
2900IU, vitamin D 1200IU, vitamin E 15IU, cobalt 0.1mg, copper 9mg, iodine 0.25mg, iron 30mg, manganese 40mg, selenium
0.3mg, zinc 30mg.
Feed mulberry：Feed mulberry is different from general mulberry tree, and it is a kind of leaf, branch bar plant capable of using as feed, because of its branch
Bar is especially soft, and in addition to edible leaf, branch bar also can all be eaten to the greatest extent livestock and poultry.Feed mulberry is nutritious, containing substantial amounts of protein,
The nutritional ingredients such as carbohydrate, amino acid, cellulose, vitamin and mineral element.It is total there are some researches show, feed mulberry leaf
The ratio of protein is 23% in dry, and its amino acid has as many as 18 kinds, accounts for mulberry leaf dry more than 10%, and polyoses content is
3% or so.Secondly, feed mulberry also contains non-specific antimicrobial composition, can effectively improve body immunity and antibacterial action.Cause
This, is used for broiler breeding by feed mulberry, not only contributes to widen feed resource, alleviates feed shortage present situation, can also improve livestock and poultry
Disease-resistant function, reduce aquaculture cost, and the quality and flavor of animal products can be improved, reduce the discharge capacity of ammonia, be a kind of green
The natural feed resource of color, possesses boundless DEVELOPMENT PROSPECT.
It is anistree：Anise refers to the dry mature fruit of Chinese anise, belongs to Genera In Magnoliaceae plant.Anise is that China is distinctive
Fragrant plant, China's anistree yield are occupied an leading position in the world, and anistree annual production is 100,000 tons or so, accounts for global total yield
More than the 90% of amount.Anise contains oil of badian, sesquiterpene lactone and its derivative, flavones, benzene as common spice
The active ingredient such as propane and lignin, there is anti-oxidant, antibacterial, desinsection, improve the physiological function such as immunity and increasing leukocyte,
Contained shikimic acid also has analgesic activity in anise.
The red sage root：The red sage root derives from the drying root and rhizome of the Lamiaceae Salvia category red sage root.The red sage root is common Chinese herbal medicine, is contained
There are the fat-soluble composition of conjugation quinone ketone, the water soluble ingredient and flavonoids, sterols material of phenolic acid class.The physiological function of the red sage root
Mainly include following several respects：Anti-oxidant, the liposoluble constituent and water soluble ingredient of the red sage root are respectively provided with stronger inoxidizability, energy
Prevent Fe2+The lipid peroxidation of microsome, removing superoxide anion and hydroxyl radical free radical etc. in the liver of/cysteine induction；
Anti-inflammation, Cryptotanshinone and dihydrotanshinone Ⅰ can preferably suppress most gram-positive bacterias in fat soluble ingredient of red sage root
Growth and breeding；Protection is cardiovascular, and tanshinone compound can prevent low-density lipoprotein from aoxidizing, and then improves lipid generation
Thank, protect endothelial cell, prevent myocardial ischemia etc., the red sage root also has antiatherosclerosis, reducing myocardial infarction area, reduction
The good of the angiocardiopathies such as myocardial oxygen consumption prevents from acting on；Suppress hepatic injury, the red sage root can promote adipose metabolism, play
The effect of reducing blood lipid, and the liver cell of damage is repaired, prevent or improve liver fibrosis；Antitumor activity.
Ginger：Ginger is the rhizome of perennial herb ginger, and the plantation of ginger is mainly in Asia and Africa, with Philippine, horse
Come based on the countries in Southeast Asia such as West Asia and China.Ginger contains volatile oil, gingerol etc. as common integration of drinking and medicinal herbs plant
Bioactive ingredients, its physiological function mainly include following several respects：Anti-oxidant, the gingerol in ginger has preferably anti-oxidant
Effect, the free radical (hydroxyl, superoxide radical) in organism can be significantly removed, reduce MDA in liver brain tissue
In content, gingerol is stronger than the anti-oxidation efficacy of vitamin E and butylated hydroxy anisole；Anti-inflammation, the phase in ginger
Close active component participate in cellular immunity, improve lysozyme activity, viscous more hydrolase polypeptides in mushroom cell membrane are fallen, make its death or
Cracking, research find that ginger is respectively provided with preferably to staphylococcus aureus, bacillus, Escherichia coli and Salmonella etc.
Inhibitory action；Immunological regulation, ginger can improve the generation of antibody in spleen, improve cell phagocytic activity and NKT is thin
The activity of born of the same parents' (NK cells), and then improve immune performance；Cholesterol is reduced, ginger can improve tissue to VLDL
Exclusion, increase the bile excretion through excrement, so as to influence the regulation that intestines absorb to fat digestion；Gastric mucosa is protected, in ginger
Curcumin can by stimulate the secretion of mucoprotein play a part of protect gastric mucosa.
Garlic：Garlic is also referred to as giant garlic, calabash, thyme etc., herbaceos perennial, for the ground of Liliaceae allium garlic
Lower bulb portion.Garlic edibility is high, rich in nutrition content, contains amino acid, small peptide class, protein, enzyme, carbohydrate, dimension
Multiple components, its physiological function such as raw element, fat, inorganic salts, glycoside mainly include following several respects：Anti-inflammation, garlic pair
Various pathogens such as staphylococcus, streptococcus, Escherichia coli etc. have suppression and killing action, and do not produce drug resistance；Cell is exempted from
Epidemic disease, garlic can participate in cellular immunity, the activity of serum lysozyme and the phagocytic activity of phagocyte be improved, so as to improve body
Immunity；Strengthen gastric secretion and gastrointestinal peristalsis, stimulate appetite and promote to digest；Improve environment of chicken house, reduce mosquito, allicin
Become allicin in the presence of enzyme, allicin effectively can prevent adult flies from being bred in excrement.
The bark of eucommia：The bark of eucommia, also known as think secondary, think of celestial being, gum etc., belong to perennial deciduous tree for the Eucommiaceae bark of eucommia, in China
Plantation extensively, there are Hunan, Jiangxi, Sichuan, Guangxi, Guizhou, Shaanxi etc. in Distribution Area.Research shows that the bark of eucommia is rich in various active
Composition, such as lignanoid, iridoid, flavones, Phenylpropanoid Glycosides and polysaccharide, there is anti-inflammatory, antibacterial, antifatigue, anti-oxidant, drop blood
The multi-efficiencies such as sugar, enhancing immunologic function, and its root, leaf and Pi Douke are used as medicine, and are clinically commonly used to prevent and treat pregnant leakage
The diseases such as blood, lumbago due to the kidney deficiency, hypertension, diabetes, miocardial infarction and Cerebrovascular disorders are not smooth.The bark of eucommia or its extract are as feeding
Feed additives can effectively improve growth of animal performance, improve meat, enhancing immunity of organisms etc..
Dandelion：Dandelion system composite family herbaceos perennial, all parts of the country are distributed, alias Pu public affairs grass, Chinese violet, mother-in-law
Mother-in-law's fourth, dandelion, Pu Gongding, milk grass etc..Dandelion chemical composition includes taraxasterol, taraxacin, saponin(e, courage
Alkali, synanthrin, glucose, pectin, inositol, caffeic acid, chlorogenic acid, flavonoids etc., clinically there are antibacterial, hepatic cholagogic, anti-stomach
The effects such as ulcer, the immune, diuresis of enhancing.Research shows that dandelion stays alcohol to be sent out by discharging and adjusting in inflammatory cytokine
Face plays protective effect, and growth of the radix tarxaci methanolic extract to tumour cell has inhibitory action, radix tarxaci water extraction liquid energy
The obvious growth and breeding for suppressing leukemia cell line, Folium Taraxacum can suppress the propagation of breast cancer cell.
A kind of preparation method for the Chinese herbal medicine mixed feed for improving beef cattle immunity, comprises the following steps：
(1) feed mulberry, anise, the red sage root, ginger, garlic, the bark of eucommia, dandelion are cleaned, 72h is dried at a temperature of 65 DEG C；
(2) step (1) dried material is weighed by weight, is mixed, is put into micronizer and is crushed, and crosses 200
Mesh sieve, obtain Chinese herb feed additive；
(3) corn, dregs of beans, cottonseed cake are weighed by weight, is stirred by slow fire 5min, are mixed, are crushed to wheat bran, bone meal
After 150 mesh, mixed with salt, premix material additive and step (2) gained Chinese herb feed additive, obtain feed semi-finished product；
(4) feed semi-finished product obtained by step (3) are sent into comminutor and will be granulated, both a kind of raising beef cattle of the invention is exempted from
The Chinese herbal medicine mixed feed of epidemic disease power.
Beneficial effects of the present invention：
1st, in Chinese herb feed additive of the invention, feed mulberry contains abundant protein, and with raising immunity of organisms
Effect, while there is the inhibitory action of height to various pathogens；Anise has anti-oxidant, antibacterial, desinsection, raising immune
The physiological functions such as power, analgesia；The red sage root has the work of cardiovascular anti-oxidant, antibacterial, protection, suppression hepatic injury and antitumor activity
With；Ginger has the function that anti-oxidant, antibacterial, improves immunity, reduces cholesterol, protection gastric mucosa；Garlic has antibacterial, carried
High immunity, the effect for stimulating appetite, promoting digestion；The bark of eucommia has antibacterial, anti-oxidant, hypoglycemic, raising immunity etc. multiple
Effect；Dandelion has antibacterial, improves the effect such as immunity, hepatic cholagogic, anti-gastric-ulcer.The present invention answers above-mentioned Chinese medicine
Match somebody with somebody, feed intake, disease-resistant growth-promoting, enhancing immunity of organisms and the work for improving oxidation resistance are improved in cattle feed, having
With so as to effectively facilitate beef cattle healthy growth, raising beef nutritive value, optimization beef quality.
2nd, main composition of the present invention uses natural Chinese medicinal herb no drug residue, not produce anti-drug resistance for raw material, ensures
Edible safety, there is positive meaning to reducing the use for cultivating antibiotic medicine and beef items medicament residue, possess
Boundless DEVELOPMENT PROSPECT.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to
Limit the present invention.
Embodiment 1
A kind of Chinese herbal medicine mixed feed for improving beef cattle immunity, include the raw material of following weight parts：30 parts of corn, beans
15 parts of the dregs of rice, 10 parts of wheat bran, 15 parts of cottonseed cake, 1 part of bone meal, 45 parts of Chinese herb feed additive, 3.5 parts of salt, premix material additive 0.1
Part；
Wherein, the Chinese herb feed additive is made up of the raw material of following weight parts：60 parts of feed mulberry, anistree 0.5 part, the red sage root
6 parts, 1 part of ginger, 6 parts of garlic, 6 parts of the bark of eucommia, 1 part of dandelion.The premix material additive is：Vitamin A 2900IU, dimension life
Plain D 1200IU, vitamin E 15IU, cobalt 0.1mg, copper 9mg, iodine 0.25mg, iron 30mg, manganese 40mg, selenium 0.3mg, zinc 30mg.
Embodiment 2
A kind of Chinese herbal medicine mixed feed for improving beef cattle immunity, include the raw material of following weight parts：50 parts of corn, beans
7 parts of the dregs of rice, 17 parts of wheat bran, 7 parts of cottonseed cake, 1 part of bone meal, 40 parts of Chinese herb feed additive, 1 part of salt, 0.3 part of premix material additive；
Wherein, the Chinese herb feed additive is made up of the raw material of following weight parts：40 parts of feed mulberry, anistree 2.5 parts, the red sage root
1 part, 1 part of ginger, 4 parts of garlic, 1 part of the bark of eucommia, 4 parts of dandelion.The premix material additive is：Vitamin A 2900IU, dimension life
Plain D 1200IU, vitamin E 15IU, cobalt 0.1mg, copper 9mg, iodine 0.25mg, iron 30mg, manganese 40mg, selenium 0.3mg, zinc 30mg.
Embodiment 3
A kind of Chinese herbal medicine mixed feed for improving beef cattle immunity, include the raw material of following weight parts：47 parts of corn, beans
10 parts of the dregs of rice, 15 parts of wheat bran, 10 parts of cottonseed cake, 4 parts of bone meal, 35 parts of Chinese herb feed additive, 1.5 parts of salt, premix material additive 0.5
Part；
Wherein, the Chinese herb feed additive is made up of the raw material of following weight parts：45 parts of feed mulberry, anistree 1 part, the red sage root 3
Part, 3 parts of ginger, 3 parts of garlic, 3 parts of the bark of eucommia, 3 parts of dandelion.The premix material additive is：Vitamin A 2900IU, vitamin
D 1200IU, vitamin E 15IU, cobalt 0.1mg, copper 9mg, iodine 0.25mg, iron 30mg, manganese 40mg, selenium 0.3mg, zinc 30mg.
Embodiment 4
A kind of Chinese herbal medicine mixed feed for improving beef cattle immunity, include the raw material of following weight parts：30 parts of corn, beans
12 parts of the dregs of rice, 12 parts of wheat bran, 12 parts of cottonseed cake, 5 parts of bone meal, 20 parts of Chinese herb feed additive, 2 parts of salt, premix material additive 0.8
Part；
Wherein, the Chinese herb feed additive is made up of the raw material of following weight parts：50 parts of feed mulberry, anistree 0.5 part, the red sage root
4 parts, 4 parts of ginger, 1 part of garlic, 4 parts of the bark of eucommia, 1 part of dandelion.The premix material additive is：Vitamin A 2900IU, dimension life
Plain D 1200IU, vitamin E 15IU, cobalt 0.1mg, copper 9mg, iodine 0.25mg, iron 30mg, manganese 40mg, selenium 0.3mg, zinc 30mg.
Embodiment 5
A kind of Chinese herbal medicine mixed feed for improving beef cattle immunity, include the raw material of following weight parts：60 parts of corn, beans
5 parts of the dregs of rice, 20 parts of wheat bran, 5 parts of cottonseed cake, 5 parts of bone meal, 15 parts of Chinese herb feed additive, 0.5 part of salt, 1 part of premix material additive；
Wherein, the Chinese herb feed additive is made up of the raw material of following weight parts：30 parts of feed mulberry, anistree 3.5 parts, the red sage root
1 part, 6 parts of ginger, 1 part of garlic, 1 part of the bark of eucommia, 6 parts of dandelion.The premix material additive is：Vitamin A 2900IU, dimension life
Plain D 1200IU, vitamin E 15IU, cobalt 0.1mg, copper 9mg, iodine 0.25mg, iron 30mg, manganese 40mg, selenium 0.3mg, zinc 30mg.
Comparative example 1
Chinese herb feed additive is not added in cattle feed, includes the raw material of following weight parts：47 parts of corn, dregs of beans 10
Part, 15 parts of wheat bran, 10 parts of cottonseed cake, 4 parts of bone meal, 1.5 parts of salt, 0.5 part of premix material additive；
Wherein, the premix material additive is：Dehydroretinol 900IU, vitamin D 1200IU, vitamin E 15IU, cobalt
0.1mg, copper 9mg, iodine 0.25mg, iron 30mg, manganese 40mg, selenium 0.3mg, zinc 30mg.
Application Example 1
The safety evaluatio of Chinese herb feed additive of the present invention
1st, test objective
Influence of the Chinese herb feed additive of the present invention to mouse growth performance and organ coefficient is detected, evaluates its security.
2nd, test specimen
The water decoction (test group) and physiological saline (control group) of Chinese herb feed additive prepared by above-described embodiment 1~5.
The preparation of Chinese herbal decoction：It is accurate to weigh after 200g Chinese herbal medicines soak 30min in 2000mL distilled water, intense fire
Heating is boiled, and is then changed to slow fire, continues to decoct 30min, is stirred, is filtered while hot；Repeat and boil once, collect filtrate.Merge
Filtrate is decocted twice, 1000rpm centrifugation 15min, is taken supernatant to be condensed into 200mL using Rotary Evaporators, that is, is made 1g/mL's
Chinese herbal decoction.
3rd, test method
198 healthy mices are randomly divided into 11 groups, every group of 3 repetitions, each repeat 6 mouse, male and female half and half, difference
Mark is numbered and weighs.Using administration by gavage, 15g/kg, 30g/kg medium-height grass of the preparation of experimental group difference gavage embodiment 1~5
Medicine additive water decoction, the physiological saline of control group gavage 15g/kg, 30g/kg, daily gavage once, continuous gavage 30d.Examination
During testing, observe daily and record the daily behavior change of every mouse.During off-test, during off-test, weigh, calculate body
Weightening, and puts to death all mouse, core, liver, spleen, lung, kidney, thymic tissue, claim its weight in wet base, according to the internal organs of last re-computation mouse
Coefficient.
Body weight gains (g)=first starting weight (g)-end weight (g)；
Organ coefficient (mg/g)=organ weights (mg)/body weight (g).
4th, result of the test
Experimental result is shown in Table 1.
Influence of 1 Chinese herb feed additive of the present invention of table to mouse growth performance and organ coefficient
Result of the test shows, compared with the control, Chinese herb feed additive of the invention can be effectively increased mouse body weight and
Organ coefficient, the wherein most pronounced effects of embodiment 3, compared with the control, when given low is 15g/kg, the increase of mouse body weight gains
74.77%, heart coefficient, liver coefficient, Spleen coefficient, lungs coefficient, Kidney coefficients and thymus gland coefficient increase by 6.29% respectively,
7.72%th, 26.36%, 15.18%, 40.08%, 19.57%；When given low is 30g/kg, the increase of mouse body weight gains
64.12%, heart coefficient, liver coefficient, Spleen coefficient, lungs coefficient, Kidney coefficients and thymus gland coefficient increase by 6.04% respectively,
7.02%th, 27.66%, 15.03%, 14.96%, 16.73%.
The immune system of mouse is mainly made up of immunocyte and immune organ, and spleen and thymus gland are important immune of body
Organ, it is closely related with immune generation.Because internal disease cell of exempting from is distributed in spleen and thymus gland mostly, thus spleen and
The structure and weight change of thymus gland reflect the immune level of animal to a certain extent, the phase if spleen with thymic weight increase
Enhancing to showing immunologic function, therefore, the relative size of organ coefficient can illustrate the power of its function to a certain extent.
5th, conclusion
In this experiment, with the Chinese herb feed additive water decoction gavage prepared by embodiment 1~5, make each internal organs of mouse
Coefficient has different degrees of rise, shows the Chinese herb feed additive of the present invention not only without obvious toxic-side effects, and can also strengthen
Mouse appetite, puts on weight, and has certain immunoregulation effect, can use safely in production.
Application Example 2
A kind of Chinese herbal medicine mixed feed of raising beef cattle immunity of the present invention is to wean calf growth performance, immune indexes
And the influence of blood antioxidant index
Or so 4 monthly ages, healthy disease-free, the similar wean calf 72 of body weight are selected, is randomly divided into 6 groups, every group of 3 weights
It is multiple, it is each to repeat 4, the embodiment of the present invention 1~5 and the cattle feed prepared by comparative example 1 are fed respectively.Test preliminary trial period
10d, it is positive to try phase 60d.Expelling parasite and colony house sterilization are uniformly carried out in preliminary trial period, using tying drylot feeding mode, fixing groove position and ox bed.
It is daily to clean colony house and periodically sterilize, colony house sanitation and hygiene are kept, health status of the observation for examination ox is paid attention at any time, such as finds different
Reason condition, is handled in time.
Every test ox feed intake of daily accurate recording, initially feed and advance in morning with off-test in experiment respectively
Row is weighed, and calculates its average daily gain, average daily gain, feed-weight ratio and the incidence of disease；And experiment is initial and off-test in
Sterile working collection jugular vein blood before morning feeding, the blood of collection is centrifuged into 15min in 4 DEG C of refrigerated centrifuge 3000r/min,
Serum is separated, is sub-packed in Eppendorf pipes, -20 DEG C freeze, for determining its Immunoglobulin IgA, IgG, IgM content, and it is anti-
Oxidation index TAC, glutathione peroxidase and total number born activity, mda content.
1st, to the influence for the calf growth performance that weans
A kind of influence of the Chinese herbal medicine mixed feed of raising beef cattle immunity of the present invention to the calf growth performance that weans is shown in
Table 2.
Influence of the table 2 to the calf growth performance that weans
Compared with comparative example, the cattle feed prepared by 5 embodiments of the invention can effectively improve the flat of wean calf
Equal daily gain, average daily gain, feed-weight ratio and the incidence of disease are reduced, wherein, the action effect of embodiment 3 is most notable, with comparative example
Compare, wean calf average daily gain adds 32.20%, and average daily gain, feed-weight ratio and the incidence of disease reduce respectively
9.86%th, 31.89%, 91.59%.Result of the test shows, a kind of compound feeding of Chinese herbal medicine of raising beef cattle immunity of the invention
Material can promote wean calf to grow, improve efficiency of feed utilization, ensure to connect the intake of ox feeding period nutriment, be it
Grow and necessary precondition is provided.
2nd, to the influence for the calf immune indexes that wean
A kind of influence of the Chinese herbal medicine mixed feed of raising beef cattle immunity of the present invention to the calf immune indexes that wean is shown in
Table 3.
Influence of the table 3 to the calf immune indexes that wean
Immunoglobulin (including IgA, IgG, IgM, IgD, IgE and IgM) is one group of protein with antibody activity, by
B cell by Proliferation, Differentiation after antigenic stimulus into thick liquid cell produce, can with corresponding antigentic specificity combine participate in body fluid exempt from
Epidemic disease, there is the biological functions such as antiviral, activating complement.
Table 3 is understood, during on-test, Immunoglobulin from Bovine Serum IgA, IgG, IgM content difference is not notable.With contrast
Example is compared, and the cattle feed prepared by 5 embodiments of the invention can effectively improve immunoglobulin in wean calf serum
IgA, IgG, IgM content, wherein, the action effect of embodiment 3 is most notable, and compared with comparative example, wean during off-test calf blood
Immunoglobulin IgA, IgG, IgM content add 34.33%, 10.40%, 21.43% respectively in clear.Result of the test shows,
A kind of Chinese herbal medicine mixed feed of raising beef cattle immunity of the present invention, which has, improves body immune system function, strengthen immunity
Effect.
3rd, to the influence for the calf blood antioxidant index that weans
A kind of Chinese herbal medicine mixed feed of raising beef cattle immunity of the present invention is to wean calf blood antioxidant index
Influence is shown in Table 4.
Influence of the table 4 to the calf blood antioxidant index that weans
TAC is to weigh the strong and weak composite target of body anti-oxidation function, reflects body antioxidant system
By the external compensatory capacity irritated.Glutathione peroxidase is a kind of peroxide catabolic enzyme being widely present in body,
It can make poisonous peroxide be reduced into nontoxic hydroxy compounds, and then protect the 26S Proteasome Structure and Function of cell membrane not by peroxide
The interference and infringement of compound, play an important role to the metabolic balance of body free radical.Total number born is organism
Interior important antioxidase, it is the primary material for removing free radical, key is played during body disequilibrium of oxidation and antioxidation
Property effect.MDA is the end-product that oxidation reaction occurs in lipid for Free Radical in organism, can not only reflect lipid mistake
The degree of oxidation, moreover it is possible to the metabolic condition of reflection body tissue cell damage degree and oxygen radical indirectly.
What Antioxidant Indexes detected in serum the results are shown in Table 4, during on-test, total antioxidation energy in the calf serum that weans
Power, glutathione peroxidase and total number born activity, mda content difference is not notable.With comparative example phase
Than the cattle feed prepared by 5 embodiments of the invention can effectively improve TAC and paddy in wean calf serum
The sweet peptide peroxidase of Guang and total number born activity, reduce mda content, wherein, the action effect of embodiment 3 is most
Significantly, wean TAC in calf serum, glutathione peroxidase and total compared with comparative example, during off-test
Superoxide dismutase activity is respectively increased 47.29%, 71.24%, 29.69%, and mda content reduces by 38.46%.Experiment
As a result showing, a kind of Chinese herbal medicine mixed feed of raising beef cattle immunity of the invention can effectively improve calf oxidation resistance,
Prevent the destruction of body antioxidant system.
5th, conclusion
A kind of Chinese herbal medicine mixed feed of raising beef cattle immunity of the present invention can effectively improve beef cattle immunologic function, strengthen
Immunity of organisms, oxidation resistance is improved, reduces the incidence of disease, promote beef cattle healthy growth, and efficiency of feed utilization can be effectively improved,
Aquaculture cost is reduced, improves the economic benefit of raiser.Secondly, a kind of Chinese herbal medicine of raising beef cattle immunity of the invention is compound
Feed production technology is simple, and feed safety is reliable, nonhazardous effect, can be applicable in beef cattle healthy aquaculture, application prospect
It is wide.
Claims (5)
- A kind of 1. Chinese herbal medicine mixed feed for improving beef cattle immunity, it is characterised in that the raw material including following weight parts：It is beautiful 30~60 parts of rice, 5~15 parts of dregs of beans, 10~20 parts of wheat bran, 5~15 parts of cottonseed cake, 1~5 part of bone meal, Chinese herb feed additive 15~ 45 parts, 0.5~3.5 part of salt, 0.1~1 part of premix material additive；The Chinese herb feed additive is made up of the raw material of following weight parts：30~60 parts of feed mulberry, anistree 0.5~3.5 part, the red sage root 1~6 part, 1~6 part of ginger, 1~6 part of garlic, 1~6 part of the bark of eucommia, 1~6 part of dandelion.
- 2. a kind of Chinese herbal medicine mixed feed for improving beef cattle immunity according to claim 1, it is characterised in that including under State the raw material of parts by weight：40~50 parts of corn, 7~12 parts of dregs of beans, 12~17 parts of wheat bran, 7~12 parts of cottonseed cake, bone meal 1~5 Part, 20~40 parts of Chinese herb feed additive, 1~2 part of salt, 0.3~0.8 part of premix material additive；The Chinese herb feed additive is made up of the raw material of following weight parts：40~50 parts of feed mulberry, anistree 0.5~2.5 part, the red sage root 1~4 part, 1~4 part of ginger, 1~4 part of garlic, 1~4 part of the bark of eucommia, 1~4 part of dandelion.
- 3. a kind of Chinese herbal medicine mixed feed for improving beef cattle immunity according to claim 2, it is characterised in that including under State the raw material of parts by weight：47 parts of corn, 10 parts of dregs of beans, 15 parts of wheat bran, 10 parts of cottonseed cake, 4 parts of bone meal, Chinese herb feed additive 35 Part, 1.5 parts of salt, 0.5 part of premix material additive；The Chinese herb feed additive is made up of the raw material of following weight parts：45 parts of feed mulberry, anistree 1 part, 3 parts of the red sage root, ginger 3 Part, 3 parts of garlic, 3 parts of the bark of eucommia, 3 parts of dandelion.
- 4. a kind of Chinese herbal medicine mixed feed for improving beef cattle immunity according to claim 3, it is characterised in that described pre- Batch mixing additive is：Dehydroretinol 900IU, vitamin D 1200IU, vitamin E 15IU, cobalt 0.1mg, copper 9mg, iodine 0.25mg, iron 30mg, manganese 40mg, selenium 0.3mg, zinc 30mg.
- 5. a kind of preparation method of the Chinese herbal medicine mixed feed of raising beef cattle immunity as described in any one of Claims 1 to 4, Comprise the following steps：(1) feed mulberry, anise, the red sage root, ginger, garlic, the bark of eucommia, dandelion are cleaned, 72h is dried at a temperature of 65 DEG C；(2) step (1) dried material is weighed by weight, is mixed, is put into micronizer and is crushed, and crosses 200 mesh sieves, Obtain Chinese herb feed additive；(3) corn, dregs of beans, cottonseed cake are weighed by weight, is stirred by slow fire 5min, are mixed with wheat bran, bone meal, are crushed to 150 mesh Afterwards, mixed with salt, premix material additive and step (2) gained Chinese herb feed additive, obtain feed semi-finished product；(4) feed semi-finished product obtained by step (3) are sent into comminutor and will be granulated, both a kind of raising beef cattle immunity of the invention Chinese herbal medicine mixed feed.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111772045A (en) * | 2020-08-24 | 2020-10-16 | 华南农业大学 | Traditional Chinese medicine residue feed for improving immunity of beef cattle and preparation method thereof |
| CN115624100A (en) * | 2022-10-31 | 2023-01-20 | 忻城县中投牧业有限公司 | Beef cattle feed and preparation method thereof |
-
2017
- 2017-08-16 CN CN201710704202.8A patent/CN107494938A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111772045A (en) * | 2020-08-24 | 2020-10-16 | 华南农业大学 | Traditional Chinese medicine residue feed for improving immunity of beef cattle and preparation method thereof |
| CN115624100A (en) * | 2022-10-31 | 2023-01-20 | 忻城县中投牧业有限公司 | Beef cattle feed and preparation method thereof |
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