CN107441387A - A kind of Chinese medicinal formulae for being used to treat damp-heat constitution acne - Google Patents

Abstract

The present invention relates to a kind of Chinese medicinal formulae for being used to treat damp-heat constitution acne.Its prescription is made up of the Chinese medicine of following parts by weight：Dry reed rhizome, Semen Coicis Semen Coicis, peach kernel, purslane, cordate houttuynia, mulberry leaf, lophatherum gracile, the root of Dahurain angelica, peppermint, cassia seed.This Chinese medicine passes through scientific composition, and Clinical practice checking curative effect through experimental study and for many years.It has the effect of fine to damp-heat constitution acne.

Description

A kind of Chinese medicinal formulae for being used to treat damp-heat constitution acne

Technical field

The present invention relates to the field of Chinese medicines, is a kind of Chinese medicinal formulae for treating damp-heat constitution acne.

Background technology

Acne is a multi-factor disease, it is now known that with female/androgen imbalance, sebaceous glands hyperfunction, microorganism, immune Horizontal and inflammation-related.Without acne as the youth is previous；The frequent premenstrual acne of women aggravates, and internal Serum Testosterone Levels increase, Increase smegma, build up in being not easy to discharge in hair follicle, cause hair follicle embolism to form acne, original is present in intrafollicular Cuo Sore corynebacteria is bred under anaerobic, produces dissolved lipase, is decomposed the triglyceride in sebum, is discharged free fat Fat acid, hair follicle stimulating cause inflammation, further make follicular wall impaired and rupture, cause perifollicolar inflammation to form acne.

The current clinically how oral administration and externally used medicine combined treatment of doctor trained in Western medicine.Endo-medicine has vitamin B2, vitamin B6, compound Vitamin B preparation, vitamin E and vitaminAD；Retinoid；Endocrine inhibitor, such as diethylstilbestrol estrogens preparation, Antiandrogen preparation, corticosteroid formulations etc.；Antibiotic, zinc preparation etc..These medicines for oral administration often coordinate a variety of lotion knots Close and use.These heteropathy, there is certain effect, but recur green higher.The reason for possible is that acne is that multi-factor comprehensive reaches After balance, the symptom that is showed on local skin.For the preparation of certain single reason, after the environment after organism adaptation administration, When these factors reach balance again, it is possible to break out again.

Someone is according to modern pathology physiological Study, it is believed that acne locally has Propiobacterium and other resident bacteria, such as golden yellow The amount reproductions such as staphylococcus, patients with acne blood viscosity are higher.Therefore there is inhibitory action with the growth and breeding to this quasi-microorganism Antipyretic, with reference to drug for invigorating blood circulation and eliminating stasis, based on be aided with the medicine of clearing damp and promoting diuresis, qi-regulating drug as treatment acne.

The traditional Chinese medical science thinks that acne belongs to interior excess heat, strongly fragrant long detoxification, involves blood system and forms.Ancient literature thinks the generation of acne, It is relevant with " being invaded outside cold-dampness, interior hot closing ".For site of pathological change, the bright stomach of face category sun, lip belongs to lunar spleen, and acne is most easy Send out in these positions, in addition lung associating with skin and hair, so this disease is related to lung, spleen, stomach；Said from the interpretation of the cause, onset and process of an illness, the main blood of the heart, " all sufferings sores are all Belong to the heart ", it liver controlling conveyance and dispersion, stagnation of liver qi, must not dissipate, change fire into poison, therefore the heart, liver two are dirty also in close relations.The traditional Chinese medical science says that " gas has Remaining is fire ", " six gas all can be from cremate ", five will are strongly fragrant can also to change fire long, and fire is strongly fragrant, be main caused by interior hot (especially damp and hot) One of reason, and acne, it is exactly one of this " fire is strongly fragrant " card external manifestation.The method for the treatment of, when in accordance with《Interior warp》" fiery Yu Ze hairs It " reason.So-called " hair ", for the meaning of diverging, Zhang Zi and meaning " hair for sweat it, make its evacuate ".

Acne is as caused by lung channel stasis, damp-heat accumulation.Damp being a kind of YIN pathogen, mechanism of qi is checked, damages yang-energy：Damp evil is viscous, It is detained in zang-fu differentiation, usually checks mechanism of qi, makes ascending or descending movement of vital Qi incompetent.It is strongly fragrant and change fire, burning hot heresy, easy folder poison, invade blood Point, gathering can send out as early stage of pyogenic infection of skin in part, slough into purulence.Burning hot high Sheng, easily consumes healthy tendency, disappear bright body fluid, and easy gas consumption hinders Tianjin, gas occurs The moon two is hindered.The key of acne is " interior hot closing ".Strongly fragrant to dissipate, heat is preferably clear.But dissipate person be mostly pungent-warm product, help fiery heat it Dislike；Clear person is mostly cold and cool product, cold tending to coagulate and stagnate, cold having property of contraction, there is the suspicion for aggravating closing.Therefore, no matter above said basis shows Studied in pathologic, physiologic, draw based on heat clearing and blood circulation promoting, be aided with clearing damp and promoting diuresis qi-regulating to treat big method, or clear scattered method, all It is both advantageous and disadvantageous.Medication is careless slightly, will be in a hopeless position.

Present invention incorporates tcm constitution theory.Constitution be human body heredity and it is acquired on the basis of show Function and form on metastable inherent characteristic, but constitution is also adjustable simultaneously.Body disease in during Constitution Theory in TCM Correlation theory just talks about the purpose that can reach treatment relevant disease by the conditioning to constitution and intervention.Come from constitution theory in traditional Chinese medicine See, patients with acne might not all be damp-heat constitution, and the people for belonging to damp-heat constitution also not can long acne.But damp-heat constitution people is The group of people at high risk of acne, the probability of its long acne will be far above ordinary person, therefore, can be by nursing one's health damp-heat constitution, to treat acne. The present invention is directed to these pathogenic characteristics of damp and hot body south acne, and according to clinical experience, medicine is selected in discretion.When strongly fragrant and change fire, fiery poison is fluffy When Sheng, because symptomatic treatment in acute condition, when clearing heat and detoxicating.But it should be noted that this hankers having wet, uses cold and cool product with caution, to prevent hindering just, causes Deficiency of vial QI, implementation is ineffective, makes the stasis of blood stagnant difficult clear.When eliminating the phlegm humidifying is strongly fragrant, it is subject to table, to damp evil, heat evil with outlet.Dispelling When heresy, the adjustment inclined damp-heat constitution of ferritic is taken into account, and is prevented repeatedly.Therefore treatment acne works as clearing heat and promoting diuresis, and detoxify table, dissolving stasis Phlegm.The prescription of this invention belongs to treatment damp-heat constitution acne core prescription, portion of main inventive people's behaviour society, degree committee of State Council National old docter of TCM's medicine expert that member's meeting, the Ministry of Education, the Ministry of Public Health, 5 big ministries and commissions of State Administration of Traditional Chinese Medicine joint are assert, career in medicine more than 50 Year.Clinically healing acne patient reaches hundreds of examples for plus-minus change based on this side for many years.The claims in the present invention are led The medicinal material content range opened is specifically for the recipe quantity designed in patent medicine and food development, its prescription medicinal material usage amount composition For situation of change from not publicly leaking, all very refining is reasonable for the prescription and dosage of prescription of the present invention, safe to use, especially suitable Hair is run jointly into the Chinese patent drug and food for the treatment of acne.

The content of the invention

This invention provides a kind of Chinese medicinal formulae for being used to treat damp-heat constitution acne, is that inventor controls through clinic for many years The summary of acne experience is treated, for damp-heat constitution acne, is started with from regulation damp-heat constitution, and make a special trip to a certain place and be directed to damp-heat constitution and green grass or young crops The mouthfeel of year crowd carries out prescription screening design to strengthen the compliance that patient takes.It is provided by the present invention damp and hot for treating The Chinese medicinal formulae of constitution acne has curative for effect, refining formula safety, is particularly suitable for new Chinese medicine and food industries exploitation.

The technical solution adopted by the present invention is：

A kind of Chinese medicinal formulae for treating acne, it is characterized in that being made up of the Chinese medicine of following parts by weight：

Dry reed rhizome 10-30 parts, Semen Coicis Semen Coicis 10-30 parts, peach kernel 5-15 parts, purslane 10-30 parts, cordate houttuynia 10-30 parts, Mulberry leaf 10-30 parts, lophatherum gracile 5-15 parts, root of Dahurain angelica 5-15 parts, peppermint 10-20 parts, cassia seed 10-20 parts.

As preference：

The Chinese medicine material parts by weight form as follows：Dry reed rhizome 15-25 parts, Semen Coicis Semen Coicis 15-25 parts, peach kernel 6-12 parts, Purslane 15-25 parts, cordate houttuynia 12-18 parts, mulberry leaf 12-18 parts, lophatherum gracile 6-12 parts, root of Dahurain angelica 6-12 peppermint 12-18 parts, Cassia Sub- 12-18 parts.

Further preferably institute's Chinese medicine material parts by weight are configured to：Dry 20 parts of reed rhizome, 20 parts of Semen Coicis Semen Coicis, 10 parts of peach kernel, horse 20 parts of bitterroot, 15 parts of cordate houttuynia, 15 parts of mulberry leaf, 10 parts of lophatherum gracile, 10 parts of the root of Dahurain angelica, 15 parts of peppermint, 15 parts of cassia seed.

The major function of Chinese medicinal formulae of the present invention is：Clearing heat and promoting diuresis, detoxify table, dissolving stasis resolving sputum.For it is papular, Acne, pustular, nodositas, Cystic or acne conglobata, with seeing the cunning light of face amount, dry mouth with bitter taste, dry and hard excrement or It is viscous not well, scanty drak urine, dysphoria, red tongue body, yellow and greasy fur, slippery and rapid pulse etc..Its prescription side's solution is that the mechanism of action is：

Acne is also known as " whelk ", " acne ", is the chronic inflammatory skin of most common pilosebaceous follicle.From the youth After phase, almost everyone can be on the face or other positions are with acne, simply time length, the problem of amount volume is few.Acne Typical performance is papule, blackhead, warts, abscess, tubercle, tumour, or even scar, is often hindered attractive in appearance.This disease belongs to the traditional Chinese medical science " lung wind Acne ".The traditional Chinese medical science thinks that this sick main pathogenesis is lung channel stasis, damp-heat accumulation.

《Records of Tradition Chinese and Western Medicine in Combination》Think：The root of reed occupy water-bed, its energy clearing lung-heat heat cool in nature of its liter ... cool in nature and kind, in Sky can manage lung qi, and sweet more liquid, kind nourishing lung yin.《Medical center bun will》Think reed rhizome：Energy excreting dampness water-filling, treats lung carbuncle.The heart of a lotus seed The seed of jog's tears,《Compendium of Materia Medica》Think：The bright medicine of coix seed sun, energy invigorating the spleen, beneficial stomach, reinforcing the mother-organ to treat deficiency, therefore consumptive lung disease lung carbuncle uses it.《This Grass is stated》Think：Coix seed, dehumidifying and not as two arts help it is dry, heat-clearing and not as a kind of reed mentioned in ancient books, even generation damage it is cloudy, QI invigorating and not as joining, art generation still Grow it is damp and hot, really for benefit in gas key medicine.《Book on Chinese herbal medicine is newly organized》Think：The most kind Li Shui of adlay, the gas ... that unlikely loss is Kidney-Yin is regarding disease Weight, the number of mutatis mutandis medicine, then negative and positive are not hindered, and diseases caused by dampness is easily gone.We are risen without solidifying with the clear lung heat of dry reed rhizome；Coix seed Dampness removing invigorating the spleen apocenosis, and the product without ginseng, art grow damp and hot anxiety；Two medicine phases are matched somebody with somebody, clearing heat and promoting diuresis apocenosis, for main pathogenesis If therefore it is monarch drug in a prescription.《Medication heart method》Think peach kernel：Hardship is to let out stagnant blood, the new blood of Gan Yisheng, therefore blood coagulation must be used.The heat gone again in blood. 《Former sick formula》Cloud：All sufferings sores, all belong to internal heat.The cold energy radiating of cool blood of dent Ai Xin, therefore primary symptom knot, ulcerative carbuncle malignant boil swell, it is white bald, and three 16 kinds of wind knot sores.《Bencao Jingshu》Think mulberry leaf：It is sweet to tremble with fear so cool blood so beneficial blood, it is sweet it is cold be harmonious, therefore lower gas and benefit is cloudy. We select peach kernel dissipating blood stasis with potent drugs, relax bowel；Purslane clearing heat and promoting diuresis；Cordate houttuynia is clearing heat and detoxicating, the carbuncle that disappears apocenosis, and can dampness removing； Mulberry leaf eliminating heat from the lung, dispelling wind and heat from the body, four be ministerial drug altogether.Lophatherum gracile reducing fever and causing diuresis；The saturating purulence of root of Dahurain angelica detumescence, to treat Head And Face disease The key medicine of disease, has whitening effect concurrently；The light surname dissipate of peppermint, there is a dispelling wind and heat from the body, declares the work(of poison table thoroughly, to damp evil and heat evil to go out Road；Cassia seed clearing away heat and loosing the bowels, four medicines are adjutant altogether.All medicine phases are closed, and play clearing heat and promoting diuresis altogether, detoxify table, the work(of dissolving stasis resolving sputum.

The pharmacological action of each compatibility Chinese medicine is described below in prescription：

Reed rhizome is grass reed Phragmites communis Trin. fresh or dry rhizome.It is annual equal It can excavate, remove bud, fibrous root and membranaceous leaf, using fresh herb or dry.It is sweet, it is cold in nature.Attach to the lung and stomach meridians.With clearing heat and promoting fluid, relieving restlessness, Preventing or arresting vomiting, the effect of diuresis.For pyreticosis polydipsia, stomach hot vomiting, cough with lung heat, lung carbuncle pyemesis, puckery pain of heat gonorrhea.Reed rhizome contains vitamin B1, B2, C and protein, fat, carbohydrate, asparagine, amino acid, aliphatic acid, sterol, tocopherol, polyhydric phenols is such as Caffeic acid and gentianic acid, Coixol, tricin, β-amyrin, taraxerol, dandelion tremble with fear ketone and by arabinose, The polysaccharide that the relative molecular mass that xylose and glucose is formed is about 20000, it is p- also containing 2,5- dimethoxys-p- benzoquinones Hydroxy benzaldehyde, syringaldehyde, coniferyl aldehyde, vanillic acid, forulic acid, p-coumaric acid and dioxane lignin.The oxygen of the latter Change the derivative of the guaiaci lignum phenolic group that catabolite is phenylpropyl alcohol alkane, cloves phenolic group and 4- hydroxy phenyls.Pharmacological action has：This product institute The Coixol contained has inhibitory action to skeletal muscle, can suppress contractile response caused by the electro photoluminescence of frog neuromuscular sample and big The oxygen intake and anaerobic glycolysis of mouse diaphram, and the reaction of actin-adenosine triphosphate system can be suppressed, it is also weaker Central inhibitory action, show as having sedation to rat and mouse, and can be with caffeine phase antagonism.There is analgesic activity, by force Degree is similar to aminopyrine.There is refrigeration function, to TTG (the refined complex polysaccharides of Pseu-domonas fluorescens thalline Class) heat pyrexia refrigeration function it is preferable, to heating caused by dinitrophenol dinitrophenolate without very acting on.To polysynaptic reflex (cat nervus peronaeus-calf Myenteron sample) there is of short duration inhibitory action.Intravenous injection can cause the of short duration decline of rabbits blood pressure, and hypodermic injection can slightly have blood glucose Decline, be in inhibitory action to Isolated Toad Heart and isolated rabbit intestines, rabbit ear blood vessel is had no significant effect.To isolated guinea pig intestinal tube There is relexation, significant can suppress isolated rabbit intestinal contraction, slow down peristaltic contraction；Thyroxine in blood can be raised；Have slight Antioxidation, prevent adrenergic oxidation；There is slight estrogen-like action.

Coix seed：For grass Job's tears Coix lacryma-jobi L.var.ma-yuen (Roman.) Stapf's Dry mature kernal.It is sweet, light, it is cool in nature.Enter spleen, stomach, lung channel.With invigorating the spleen excreting dampness, remove numbness antidiarrheal, the effect of dense, is arranged in heat-clearing. It is clinically used for oedema, tinea pedis, difficult urination, arthritis with fixed pain caused by dampness contraction, splenasthenic diarrhea, lung carbuncle, acute appendicitis；Flat wart etc..Modern study is main Composition has protein, fat, carbohydrate, amino acid (for leucine, lysine, arginine, tyrosine etc.), Coixol, the heart of a lotus seed Job's tears ester, triterpenoid, a small amount of vitamin B1 etc..Pharmacology confirms coix seed oil (predominantly palmitic acid and its ester) to breathing, small Amount is excited, a large amount of to benumb (central)；Pulmonary Vascular can be made significantly to expand.To isolated frog heart and isolated rabbit intestines, low concentration is in excitement Effect, high concentration is in inhibitory action；To rabbit and cavy uterus typically in excitation, adrenaline can invert its excitement and make With；It also has antidiuretic activity；Can largely animal be benumbed, have inhibitory action to striated muscle, to cancer cell have prevention grow up and The effect such as injury.

Peach kernel：For rosaceous plant peach Prunus persica (L.) Batsch or mountain peach Prunus davidiana (Carr.) Franch. dry mature seed.Sweet-bitter flavor, it is mild-natured.Enter the heart, liver.Large intestine channel.With promoting blood circulation, relax bowel The effect of.It is clinically used for Amenorrhea, dysmenorrhoea , abdominal lump of mass in abdomen, injury from falling down, dry constipation of intestines etc..Modern study its contain peach kernel containing hardship Almond glucoside, volatile oil, fat oil, glucose, protein, sucrose etc.；Master contains olein and a small amount of linoleic acid in oil Ester.Separately containing emulsin etc..Pharmacology confirms to have expansion blood vessel, reduces the effect such as blood viscosity, anti-inflammatory, antiallergy.

Purslane：For portulacaceous plant purslane Portulaca oleracea L. dry aerial parts.It is sour, It is cold in nature.Enter bar, large intestine channel.With clearing heat and detoxicating, the effect of cooling blood and hemostasis.It is clinically used for being used for toxic-heat and blood stasis, carbuncle swells furunculosis is wet Rash, erysipelas, snake bite and insect sting, have blood in stool, hemorrhoid blood, metrostaxis etc..Main component have norepinephrine (noradrenaline) and Sylvite (including potassium nitrate, potassium chloride, potassium sulfate and other sylvite, also containing DOPA (dopa), dopamine (dopamine), beet Plain (betanidin), isobetanidin (isobetanidin), beet formula (betanin), different beet glucoside (isobetanin), grass Sour (oxalic acid), malic acid (malic acid), citric acid (citric acid), glutamic acid (glutamic acid), Aspartic acid (aspartic acid), alanine (alanine) and glucose (glucose), and aobvious alkaloid, tonka-bean Essence, flavones, cardiac glycoside and anthracene glucoside, fructose (fructose), sucrose (sucrose) etc..Pharmacology is confirmed with antibacterial, excited digestion Road smooth muscle, diastole skeletal muscle, have to uterus excited and suppress two-way function and improve the effect such as disorders of lipid metabolism.

Cordate houttuynia：This product is saururaceae plant houttuynia cordata Houttuynia cordata Thunb. dry aerial parts. Acrid flavour is slightly cold, return lung warp.With clearing heat and detoxicating, the carbuncle that disappears apocenosis, the effect of inducing diuresis for treating strangurtia.It is clinically used for lung carbuncle pyemesis, phlegm heat panting Cough, hot dysentery, heat gonorrhea, carbuncle sore tumefacting virus etc..Modern study main component has volatile oil, is mainly methyl nonyl ketone, cordate houttuynia in oil Element, myrcene, octanoic acid, capric acid；Separately containing quercitrin, Isoquercitrin, hyperin, rutin, potassium chloride, potassium sulfate, cordarine Deng.Pharmacology confirms there are the effects such as anti-bacteria and anti-virus, diuresis hemostasis.

Mulberry leaf are moraceae plants mulberry Morus alba L. dried leaf.Harvested after first frost, remove impurity, dry.Sweet, Hardship, it is cold in nature.Return lung, Liver Channel.With dispelling wind and heat from the body, clearing away the lungheat and moisturizing, the work(to clear liver and improve vision.For anemopyretic cold, lung-heat type cough, head Dizzy headache, hot eyes are dim-sighted.Containing rutin, Quercetin, Isoquercitrin, moracetin, micro cupreol, and Campesterol, β-D- glucosides, Lupeol, meso inositol, molting hormone Inokosterone and ecdysterone, haemolysis Element, chlorogenic acid.Separately there is volatile oil, wherein having acetic acid, propionic acid, butyric acid, isobutyric acid, valeric acid, isovaleric acid, caproic acid, isocaproic acid, bigcatkin willow Sour methyl esters, guaiacol, phenol, adjacent phenyl methylcarbamate, a phenyl methylcarbamate, Eugenol etc., again containing oxalic acid, fumaric acid, tartaric acid, lemon Acid, butanedioic acid, palmitic acid, ethyl palmitate, hentriacontane, hydroxycoumarin, sucrose, fructose, glucose, lucid asparagus amino acid With the amino acid such as glutamic acid, and vitamin C, glutathione, folic acid, 5- formyl tetrahydrofolic acids, vitamin B1, vitamin B2, The trace element such as adenine, choline, trigonelline, Yi Jitong, zinc, boron 35, manganese has certain antibacterial, blood sugar reducing function, and right Intestinal smooth muscle inhibitory action, excited estrus uterine smooth muscle etc..

Lophatherum gracile is grass henon bamboo leaf Lophatherum gracile Brongn. drying cauline leaf.Summer is not Tap, dry before taking out flower spike.It is sweet, light, it is cold in nature.The thoughts of returning home, stomach, small intestinl channel.With clearing heat and relieving fidgetness, the effect of diuresis.For heat Sick polydipsia, hot urination leaching pain, aphthae.Containing triterpenoid：Arundoin, Cylindrin, taraxerol and freidelin (fiiedelin).Another meaning aerial part is containing phenolic constituent, amino acid, organic acid, carbohydrate.Present research have shown that its it is water-soluble into Divide has refrigeration function, weaker diuresis to heating caused by yeast Escherichia coli, and increases the excretion of urine chloride, with And weaker bacteriostasis, blood glucose increasing effect.

The root of Dahurain angelica：For umbellate form section the plant root of Dahurain angelica Angelica dahurica (Fisch.ex Hoffm.) Benth.et Or Radix angelicae dahuricae Angelica dahurica (Fisch.ex Hoffm.) Benth.et Hook.f. Hook.f.var.formosana (Boiss.) Shan et Yuan dry root.Acrid flavour, it is warm-natured.Return stomach, large intestine, lung channel.Work( Wind dehumidifying, sensible analgesic, detumescence and apocenosis can be dissipated.Before Isomperatorin, Imperatorin, bergapten, phellopterin, oxidation Hu Su etc..With effects such as antipyretic-antalgic, spasmolysis, decompression, antimicrobial antiphlogistics.Clinic is usually used in cold headache, pain in the supra-orbital bone, nose Plug, nasosinusitis, toothache, leukorrhea, sore swell and ache curative etc..

Peppermint：For Labiatae mint peppermint Mentha haplocalyx Briq. dry aerial parts.Taste It is pungent, it is cool in nature.Return lung, Liver Channel.Function dispelling wind-heat.Refresh oneself, promoting eruption.The main taste menthol of volatile oil, menthones, also containing acetic acid Menthyl ester, amphene, limonene, isomenthone, firpene, piperitenone, resin etc..Menthol topical application can control headache, nerve Bitterly, itch etc..For anemopyretic cold, wind-warm syndrome is from the beginning of, headache, hot eyes, larynx numbness, aphtha, rubella, measles, Breast bilges frowsty.

Cassia seed is legume Cassia Cassia obtusifolia L. or little Cassia tora Cassia tora L. drying Mature seed.Autumn harvests ripening fruits, dries, and lays seed, removes impurity.It is sweet, bitter, salty, cold nature.Return liver, large intestine Through.With heat-clearing improving eyesight, the work(to relax bowel.Containing Chrysophanol, rheum emodin, aloe-emodin, Rhein, rheum emodin glucose Glucoside, emodin anthrone, Physcion, obtusin, aurantio-obtusin, and rubrofusarin, Cassia pine, Cassia Lactone and vitamin A.With certain decompression, antibacterial and discharge function.The puckery pain of hot eyes is clinically used for, the more tears of photophobia, is had a headache dizzy Dizzy, mesh is secretly failed to understand, constipation.

Clinical research

Clinical research statistics display through 120 patients with acne of inventor, use using prescription of the present invention as basic side's treatment In damp-heat constitution acne 1 month, total effective rate is up to more than 90% (clinical cure：Therapeutic index is up to more than 95%；It is effective：Curative effect Index is between 70~95%；Effectively：Therapeutic index is between 50~70%；It is invalid：Therapeutic index is less than 50), during treatment Have no adverse events.

Typical clinical case

Case 1：

Wu, female, student at school, 20 years old.In November, 2008 goes to a doctor.Tcm constitution is recognized as damp-heat constitution.Main suit face Cuo Sore more than 2 years, usually study is nervous, insomnia and dreamful sleep, and premenstrual acne aggravates.Existing lip week, two cheek acnes are more, and rash color is red, hoary hair's powder Thorn, there is a small amount of tumour.Control with clearing heat and promoting diuresis, detoxify table, takes prescription of the present invention.Examined again after 7 doses, acne mitigates.Day before yesterday row Through the past premenstrual acne aggravates, and this occurs without new acne.Being taken again 2 weeks with prescription of the present invention afterwards, face acnes all disappear, Do not occur new acne before menstruation, have rosy cheeks.

Case 2：

What certain, man, student at school, 22 years old.In September, 2009 is gone to a doctor.Tcm constitution is recognized as damp-heat constitution.Main suit's acne is repeatedly Breaking-out 7 years, was once treated with multi-medicament.Existing tubercle, tumour are simultaneously existing, forehead, two cheeks, lip week acne it is more, local more purulence head； Hair oil is more, and sweat is few, and the fat big matter of tongue is red, and tongue is thick yellow, slippery.With clearing heat and promoting diuresis, detoxify table, dissolving stasis resolving sputum.Taken effect when examining again, Cuo Sore is almost recovered.Continue with 7 doses of prescription of the present invention, acne takes a turn for the better earlier above, and tumour part eliminates.Prescription of the present invention is given to imitate admittedly again.2 Acne disappears after month, and erythema does not show, and only part scar is not moved back.

Case 3：

Poplar, female, 18 years old.In July, 2010 goes to a doctor.Tcm constitution is recognized as damp-heat constitution.Main suit's fash half a year, send out repeatedly Make.Nearly first quarter moon fash substantially aggravates, papule, acne increasing number, partially visible purulence head.Face goes out Chuck Steak, red tongue with thin and yellowish fur, Superficial and rapid pulse.With 7 doses of prescription of the present invention.Examine and occur without new fash again, raw hide rash has disappeared.Continue 7 doses of prescription of the present invention, face Fash disappears substantially, only kermesinus pigmentation.After taking 7 doses again, clinical recovery.

Prescription of the present invention is effective to the treatment safety of acne in summary, can effectively improve the symptom of acne trouble, group Side's refining, it is safe to use, exploitation is especially suitable for into Chinese medicine preparation (patent medicine) or food.

Embodiment

The present invention is further illustrated with reference to embodiments.

Embodiment 1

Dry 20 parts of reed rhizome, 20 parts of Semen Coicis Semen Coicis, 10 parts of peach kernel, 20 parts of purslane, cordate houttuynia 15 are weighed respectively by weight Part, 15 parts of mulberry leaf, 10 parts of lophatherum gracile, 10 parts of the root of Dahurain angelica, 15 parts of peppermint, 15 parts of cassia seed.

Preparation process：

Each taste Chinese medicine that will be weighed, decoction is decocted into or during Chinese patent medicine preparation technique routinely is processed into by traditional handicraft The clinical main Chinese patent medicine preparation such as tablet, pill, capsule, granule, powder or oral liquid defined in state's pharmacopeia or according to Food is made in general food processing technology.For mediation mouthfeel, appropriate sweetener, such as Sucralose, honey element, peace can be added Honey, steviol glycoside, Momordica grosvenori glucin etc. are matched, can also add appropriate acid, for example malic acid, citric acid etc. carry out entangling taste.

Embodiment 2

Dry 30 parts of reed rhizome, 30 parts of Semen Coicis Semen Coicis, 5 parts of peach kernel, 10 parts of purslane, cordate houttuynia 30 are weighed respectively by weight Part, 10 parts of mulberry leaf, 5 parts of lophatherum gracile, 15 parts of the root of Dahurain angelica, 20 parts of peppermint, 10 parts of cassia seed.

Preparation process is the same as embodiment 1.

Embodiment 3

Dry 10 parts of reed rhizome, 10 parts of Semen Coicis Semen Coicis, 15 parts of peach kernel, 30 parts of purslane, cordate houttuynia 10 are weighed respectively by weight Part, 30 parts of mulberry leaf, 15 parts of lophatherum gracile, 5 parts of the root of Dahurain angelica, 10 parts of peppermint, 20 parts of cassia seed.

Preparation process is the same as embodiment 1.

Embodiment 4

Dry 15 parts of reed rhizome, 15 parts of Semen Coicis Semen Coicis, 6 parts of peach kernel, 12 parts of purslane, cordate houttuynia 12 are weighed respectively by weight Part, 18 parts of mulberry leaf, 6 parts of lophatherum gracile, 9 parts of the root of Dahurain angelica, 12 parts of peppermint, 18 parts of cassia seed.

Preparation process is the same as embodiment 1.

Embodiment 5

Dry 25 parts of reed rhizome, 18 parts of Semen Coicis Semen Coicis, 9 parts of peach kernel, 25 parts of purslane, cordate houttuynia 20 are weighed respectively by weight Part, 25 parts of mulberry leaf, 9 parts of lophatherum gracile, 12 parts of the root of Dahurain angelica, 18 parts of peppermint, 12 parts of cassia seed.

Embodiment 6

Dry 12 parts of reed rhizome, 25 parts of Semen Coicis Semen Coicis, 12 parts of peach kernel, 18 parts of purslane, cordate houttuynia 25 are weighed respectively by weight Part, 12 parts of mulberry leaf, 10 parts of lophatherum gracile, 10 parts of the root of Dahurain angelica, 15 parts of peppermint, 15 parts of cassia seed.

Preparation process is the same as embodiment 1.

Embodiment 7

Dry 18 parts of reed rhizome, 12 parts of Semen Coicis Semen Coicis, 10 parts of peach kernel, 24 parts of purslane, cordate houttuynia 18 are weighed respectively by weight Part, 25 parts of mulberry leaf, 10 parts of lophatherum gracile, 10 parts of the root of Dahurain angelica, 15 parts of peppermint, 10 parts of cassia seed.

Embodiment 8

Dry 20 parts of reed rhizome, 20 parts of Semen Coicis Semen Coicis, 12 parts of peach kernel, 15 parts of purslane, cordate houttuynia 10 are weighed respectively by weight Part, 20 parts of mulberry leaf, 12 parts of lophatherum gracile, 6 parts of the root of Dahurain angelica, 12 parts of peppermint, 12 parts of cassia seed.

Preparation process is the same as embodiment 1.

Above content is only how to implement example explanation, rather than protection scope of the present invention, institute to the present invention The various modifications made to described specific embodiment of category those skilled in the art or supplement or using similar mode Substitute, structure without departing from invention or surmount scope defined in the claims, the protection of the present invention all should be belonged to Scope.

Claims (4)

1. A kind of 1. Chinese medicinal formulae for being used to treat damp-heat constitution acne, it is characterized in that being made up of the Chinese medicine of following parts by weight：

   Dry reed rhizome 10-30 parts, Semen Coicis Semen Coicis 10-30 parts, peach kernel 5-15 parts, purslane 10-30 parts, cordate houttuynia 10-30 parts, mulberry leaf 10-30 parts, lophatherum gracile 5-15 parts, root of Dahurain angelica 5-15 parts, peppermint 10-20 parts, cassia seed 10-20 parts.
2. 2. the Chinese medicinal formulae for the treatment of damp-heat constitution acne according to claim 1, it is characterized in that by following parts by weight Medicine is made：

   Dry reed rhizome 15-25 parts, Semen Coicis Semen Coicis 15-25 parts, peach kernel 6-12 parts, purslane 15-25 parts, cordate houttuynia 12-18 parts, mulberry leaf 12-18 parts, lophatherum gracile 6-12 parts, root of Dahurain angelica 6-12 parts, peppermint 12-18 parts, cassia seed 12-18 parts.
3. 3. the Chinese medicinal formulae for the treatment of damp-heat constitution acne according to claim 1, it is characterized in that by following parts by weight Medicine is made：

   Dry 20 parts of reed rhizome, 20 parts of Semen Coicis Semen Coicis, 10 parts of peach kernel, 20 parts of purslane, 15 parts of cordate houttuynia, 15 parts of mulberry leaf, lophatherum gracile 10 Part, 10 parts of the root of Dahurain angelica, 15 parts of peppermint, 15 parts of cassia seed.
4. 4. the Chinese medicinal formulae for the treatment of damp-heat constitution acne according to claim 1 is mainly made for preparing medicine and food Application in agent.