CN107432896A - One kind decayed tooth spraying and preparation method thereof - Google Patents
One kind decayed tooth spraying and preparation method thereof Download PDFInfo
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- CN107432896A CN107432896A CN201710719361.5A CN201710719361A CN107432896A CN 107432896 A CN107432896 A CN 107432896A CN 201710719361 A CN201710719361 A CN 201710719361A CN 107432896 A CN107432896 A CN 107432896A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0063—Periodont
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/35—Extraction with lipophilic solvents, e.g. Hexane or petrol ether
Abstract
The invention belongs to technical field of traditional Chinese medicines, more particularly to a kind of decayed tooth spraying and preparation method thereof.The present invention reasonably reconciles the self property of fourth eggplant, castor bean, Radix zanthoxyli, radix glycyrrhizae, peppermint, tealeaves together, based on fourth eggplant, pass through rational compatibility and processing, give full play to raw material expelling parasite, detumescence, the effect of analgesic, lasting medicine, it can be decayed tooth with long-acting preventing and treating, reduce bacterial plaque area and persistently ease pain.The decayed tooth of the present invention is sprayed using pure natural Chinese herbal medicine as raw material, does not add chemical composition, long-term use of harmless.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, more particularly to a kind of decayed tooth spraying and preparation method thereof.
Background technology
Dental caries are commonly called as decayed tooth, decayed tooth, are bacteriosises, can be with secondary pulpitis and periapical inflammation, or even can cause tooth
Groove bone and inflammation of jaws.As treated not in time, lesion continues to develop, and forms cavity, destroys disappearance completely to corona eventually, and it develops
Final result be loss of tooth.Dental caries feature is incidence of disease height, and distribution is wide.It is the main common disease in oral cavity, and the mankind are most
Itself and tumour and angiocardiopathy are listed as the big keypoint control disease of the mankind three by one of universal disease, the World Health Organization
Disease.
The toothache symptom that carious tooth is brought can have a strong impact on the daily daily life system of people, and the medicine for the treatment of toothache at present is main
There are Fu Fang Ya Tong Ding, Yazhoukang, WANTONG YANKANG pill or cow-bezoar antitoxic bolus etc., these medicines have certain treatment and analgesic effect effect
Fruit, but work slower, onset time from several hours to dozens of hour, in this process can not pain of alleviation, also
It is likely to result in that the pain increased, extends stadium.Therefore, many people are relieved the pain with Western medicine such as metronidazole, Fenbids, but this kind of Western medicine
Only there are pain-relieving functions, long-term use has side effect, it is also possible to damage periodontal nerve.
At present, people often prevent carious tooth with mouthrinse product, such as chlorohexidene product, though bactericidal effect is good, permeate
Property is poor, and long-term use can cause oral mucosa to come off, fester, and most of mouthrinse products all contain sodium benzoate
Deng preservative, long-term use can have an impact to health.
The content of the invention
In order to solve above-mentioned technical problem present in prior art, the present invention provides a kind of decayed tooth spraying and its preparation side
Method, it is achieved particular by following art scheme：
(1) in parts by weight, fourth eggplant 3-5 parts, castor bean 10-14 parts, Radix zanthoxyli 8-12 parts, radix glycyrrhizae 8-12 parts, thin are taken
Lotus 10-14 parts, tealeaves 10-14 parts, clean, dry, then take 30-40 part lards.Preferred scheme is：In parts by weight, fourth is taken
4 parts of eggplant, 12 parts of castor bean, 10 parts of Radix zanthoxyli, 10 parts of radix glycyrrhizae, 12 parts of peppermint, 12 parts of tealeaves, clean, dry, then take 35 portions of pigs
Oil.
(2) other raw materials in addition to lard are slightly dried, reduces wherein moisture, added in lard and be well mixed.
(3) raw material mixed heating is distilled, collects distillate, obtain Chinese medical extract.
(4) it will be packed after distillate pressurization cooling, spray be made.
(5) spray is heated into 10-20min at 50-75 DEG C before use, used after its somewhat dissolving.
The fourth eggplant is pulverized after fourth eggplant seed dries.
The slightly drying is to dry 30-60min at 75-85 DEG C.
The distillation is the heating distillation 4-6h at 200-300 DEG C.
Fourth eggplant：It is bitter, pungent, tepor.Energy radiating analgesic, antitussive and antiasthmatic, control traumatic injury, expelling parasite sterilization, control ulcerative carbuncle pyogenic infections.
Castor bean：Detumescence and drawing out poison, swollen ulcer drug is controlled, scabies leprosy tinea sore is controlled, controls scald.
Radix zanthoxyli：It is bitter, pungent, it is mild-natured.It is promoting blood circulation and removing blood stasis, promoting qi circulation and relieving pain, dispelling wind and removing obstruction in the meridians, removing toxicity for detumescence, flutterred particularly for falling
Damage, have a stomachache, toothache.
Radix glycyrrhizae：It is sweet, it is mild-natured.Invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription, especially slow
Solution drug toxicity, strong there is special effect.
Peppermint：Acrid flavour, it is cool in nature.Dispelling wind and heat from the body, head clearing, relieving sore-throat promoting eruption, soothing the liver promoting the circulation of qi, expelling parasite sterilization, refresh the mind.
Tealeaves：Body immunity, bactericidal can be improved, carious tooth is prevented, eliminates halitosis.
Compared with prior art, the technique effect of the invention is embodied in：
The self property of fourth eggplant, castor bean, Radix zanthoxyli, radix glycyrrhizae, peppermint, tealeaves is reasonably reconciled together, with fourth eggplant
Based on, by rational compatibility and processing, expelling parasite, detumescence, the effect of analgesic are given full play to, lasting medicine can be with long-acting preventing and treating
Decayed tooth, reduce bacterial plaque area and persistently ease pain.The decayed tooth of the present invention is sprayed using pure natural Chinese herbal medicine as raw material, not addition
Study point, it is harmless.
Embodiment
Limited with reference to specific embodiment technical scheme is further, but claimed
Scope is not only limited to made description.
Embodiment 1
One kind decayed tooth spraying, is prepared via a method which：
(1) fourth eggplant 4g, castor bean 12g, Radix zanthoxyli 10g, radix glycyrrhizae 10g, peppermint 12g, tealeaves 12g are weighed, cleans, dry,
35g lards are weighed again.
(2) by other raw materials in addition to lard at 80 DEG C heating, drying 45min, reduce wherein moisture, add in lard
It is well mixed.
(3) raw material mixed is heated into distillation 5h by the raw material mixed at 250 DEG C, distillate is collected, in obtaining
Medicament extract.
(4) it will be packed after distillate pressurization cooling, spray be made.
(5) spray is heated into 15min at 65 DEG C before use, used after it somewhat melts.
Embodiment 2
One kind decayed tooth spraying, is prepared via a method which：
(1) fourth eggplant 3g, castor bean 10g, Radix zanthoxyli 8g, radix glycyrrhizae 12g, peppermint 14g, tealeaves 15g are weighed, cleans, dry, then
Weigh 30g lards.
(2) by other raw materials in addition to lard at 80 DEG C heating, drying 45min, reduce wherein moisture, add in lard
It is well mixed.
(3) raw material mixed is heated into distillation 5h by the raw material mixed at 250 DEG C, distillate is collected, in obtaining
Medicament extract.
(4) it will be packed after distillate pressurization cooling, spray be made.
(5) spray is heated into 15min at 65 DEG C before use, used after it somewhat melts.
Embodiment 3
One kind decayed tooth spraying, is prepared via a method which：
(1) fourth eggplant 5g, castor bean 14g, Radix zanthoxyli 12g, radix glycyrrhizae 8g, peppermint 10g, tealeaves 10g are weighed, cleans, dry, then
Weigh 35g lards.
(2) by other raw materials in addition to lard at 80 DEG C heating, drying 45min, reduce wherein moisture, add in lard
It is well mixed.
(3) raw material mixed is heated into distillation 5h by the raw material mixed at 250 DEG C, distillate is collected, in obtaining
Medicament extract.
(4) it will be packed after distillate pressurization cooling, spray be made.
(5) spray is heated into 15min at 65 DEG C before use, used after it somewhat melts.
Embodiment 4
One kind decayed tooth spraying, is prepared via a method which：
(1) fourth eggplant 4g, castor bean 12g, Radix zanthoxyli 10g, radix glycyrrhizae 10g, peppermint 12g, tealeaves 12g are weighed, cleans, dry,
35g lards are weighed again.
(2) by other raw materials in addition to lard at 80 DEG C heating, drying 45min, reduce wherein moisture, add in lard
It is well mixed.
(3) raw material mixed is heated into distillation 5h by the raw material mixed at 250 DEG C, distillate is collected, in obtaining
Medicament extract.
(4) it will be packed after distillate pressurization cooling, spray be made.
(5) spray is heated into 15min at 65 DEG C before use, used after it somewhat melts.
Fourth eggplant used is the powder being ground into after fourth eggplant seed is dried.
Embodiment 5
One kind decayed tooth spraying, is prepared via a method which：
(1) fourth eggplant 4g, castor bean 12g, Radix zanthoxyli 10g, radix glycyrrhizae 10g, peppermint 12g, tealeaves 12g are weighed, cleans, dry,
35g lards are weighed again.
(2) other raw materials in addition to lard are heated at 75 DEG C and dries 60min, reduce wherein moisture, added in lard and mix
Close uniform.
(3) raw material mixed is heated into distillation 5h by the raw material mixed at 250 DEG C, distillate is collected, in obtaining
Medicament extract.
(4) it will be packed after distillate pressurization cooling, spray be made.
(5) spray is heated into 15min at 65 DEG C before use, used after it somewhat melts.
Embodiment 6
One kind decayed tooth spraying, is prepared via a method which：
(1) fourth eggplant 4g, castor bean 12g, Radix zanthoxyli 10g, radix glycyrrhizae 10g, peppermint 12g, tealeaves 12g are weighed, cleans, dry,
35g lards are weighed again.
(2) by other raw materials in addition to lard at 85 DEG C heating, drying 30min, reduce wherein moisture, add in lard
It is well mixed.
(3) raw material mixed is heated into distillation 5h by the raw material mixed at 250 DEG C, distillate is collected, in obtaining
Medicament extract.
(4) it will be packed after distillate pressurization cooling, spray be made.
(5) spray is heated into 15min at 65 DEG C before use, used after it somewhat melts.
Embodiment 7
One kind decayed tooth spraying, is prepared via a method which：
(1) fourth eggplant 4g, castor bean 12g, Radix zanthoxyli 10g, radix glycyrrhizae 10g, peppermint 12g, tealeaves 12g are weighed, cleans, dry,
35g lards are weighed again.
(2) by other raw materials in addition to lard at 80 DEG C heating, drying 45min, reduce wherein moisture, add in lard
It is well mixed.
(3) raw material mixed is heated into distillation 4h by the raw material mixed at 300 DEG C, distillate is collected, in obtaining
Medicament extract.
(4) it will be packed after distillate pressurization cooling, spray be made.
(5) spray is heated into 15min at 65 DEG C before use, used after it somewhat melts.
Embodiment 8
One kind decayed tooth spraying, is prepared via a method which：
(1) fourth eggplant 4g, castor bean 12g, Radix zanthoxyli 10g, radix glycyrrhizae 10g, peppermint 12g, tealeaves 12g are weighed, cleans, dry,
35g lards are weighed again.
(2) by other raw materials in addition to lard at 80 DEG C heating, drying 45min, reduce wherein moisture, add in lard
It is well mixed.
(3) raw material mixed is heated into distillation 6h by the raw material mixed at 200 DEG C, distillate is collected, in obtaining
Medicament extract.
(4) it will be packed after distillate pressurization cooling, spray be made.
(5) spray is heated into 15min at 65 DEG C before use, used after it somewhat melts.
Embodiment 9
One kind decayed tooth spraying, is prepared via a method which：
(1) fourth eggplant 4g, castor bean 12g, Radix zanthoxyli 10g, radix glycyrrhizae 10g, peppermint 12g, tealeaves 12g are weighed, cleans, dry,
35g lards are weighed again.
(2) by other raw materials in addition to lard at 80 DEG C heating, drying 45min, reduce wherein moisture, add in lard
It is well mixed.
(3) raw material mixed is heated into distillation 5h by the raw material mixed at 250 DEG C, distillate is collected, in obtaining
Medicament extract.
(4) it will be packed after distillate pressurization cooling, spray be made.
(5) spray is heated into 20min at 50 DEG C before use, used after it somewhat melts.
Embodiment 10
One kind decayed tooth spraying, is prepared via a method which：
(1) fourth eggplant 4g, castor bean 12g, Radix zanthoxyli 10g, radix glycyrrhizae 10g, peppermint 12g, tealeaves 12g are weighed, cleans, dry,
35g lards are weighed again.
(2) by other raw materials in addition to lard at 80 DEG C heating, drying 45min, reduce wherein moisture, add in lard
It is well mixed.
(3) raw material mixed is heated into distillation 5h by the raw material mixed at 250 DEG C, distillate is collected, in obtaining
Medicament extract.
(4) it will be packed after distillate pressurization cooling, spray be made.
(5) spray is heated into 10min at 75 DEG C before use, used after it somewhat melts.
Extracorporeal bacteria inhibitor test：
The Main Pathogenic Bacteria for causing carious tooth is Streptococcus mutans, and this bacterium is easily adhered to dental surface and forms bacterial plaque,
Then acid is produced by metabolic activity, acid makes tooth mineral matter dissolve to form tooth hole and form decayed tooth.Make a variation hammer in human oral cavity
The detection of bacterium shows that c form variation strains of streptococcus accounts for the 60-90% of oral cavity Streptococcus mutans total amount, d form variation streptococcus bacterium
Strain accounts for the 10% of oral cavity Streptococcus mutans total amount.
Under 37 DEG C of temperature conditionss, with BHI culture mediums, c types and d form variations streptococcus 48 hours are cultivated respectively, then will
C types after culture and d form variations streptococcus difference 5000rpm are centrifuged 5 minutes, collect thalline, be 6.0 with pH value, concentration be
0.2M phosphate buffer washes bacterium 3 times, then 50 DEG C be heat-treated 25 minutes, respectively be made c form variations streptococcus (2,000,000,000/ml) and
D form variations streptococcus (2,000,000,000/ml) liquid, by volume：C form variation streptococcus：D form variations streptococcus=5：1 ratio mixing,
Obtain mixovariation hammer bacterium solution.
With 3 parts of BHI culture mediums, in high pressure steam sterilization 20min；Taken respectively after cooling 700 μ l culture mediums be put into it is micro from
Heart pipe, 1 part adds the μ l of 1 spray of embodiment 200, adds the μ l of mixovariation hammer bacterium solution 100；1 part of addition Jin Zhongda is washed must
200 μ l of safe oral nursing liquid (chlorhexidine gluconate content is 0.108-0.132%), add mixovariation hammer bacterium solution
100μl；1 part of addition μ l of distilled water 200, adds the μ l of mixovariation hammer bacterium solution 100.Then, it is passed through 10%H2, 10%CO2、
80%N2Anaerobic culturel 24 hours, 600nm measure OD values.
Bacteriostasis rate=(control group OD values-experimental group OD values)/control group OD values * 100%
| Embodiment 1 | Chlorohexidene contrast groups | Blank control group | |
| Bacteriostasis rate | 87.93% | 88.32% | / |
Contrast understands that decayed tooth spraying of the invention has good fungistatic effect to Streptococcus mutans c types and d types, and its is antibacterial
Rate is close to chlorohexidene product conventional on the market.
Clinical test example：
220 patients for decayed tooth pain symptom occur are chosen, 20 people are one group, and 1 group is sprayed using the decayed tooth of embodiment 1 daily
Spray painting tooth 1 time；2 groups spray tooth 1 time using the decayed tooth spraying of embodiment 2 daily, and by that analogy, each group uses embodiment 1-10 respectively
The decayed tooth spraying of group is handled, and last group is chlorohexidene control group, reaches chlorohexidene oral nursing liquid (Portugal using golden clock daily
Grape saccharic acid chlorhexidine is 0.108-0.132%) gargle 2 times, gargled 1 minute with 15ml every time, 20d is used continuously, goes forward side by side
Dental plaque index situation of change and adverse reaction situation after line trace record 10d, 20d.
Contrast is understood, when raw material proportioning is：5 parts of fourth eggplant, 14 parts of castor bean, 12 parts of Radix zanthoxyli, 8 parts of radix glycyrrhizae, 10 parts of peppermint,
It is more suitable during 10 parts of tealeaves, it is preferable to reduce bacterial plaque effect.It is daily effectively to be subtracted using the decayed tooth spraying spray tooth of the present invention
Few bacterial plaque area, prevents from decaying tooth, and will not bring adverse reaction, does not influence daily life.
Finally it is pointed out that above example is only the more representational example of the present invention.Obviously, technology of the invention
Scheme is not limited to above-described embodiment, can also there is many deformations.One of ordinary skill in the art can be from disclosed by the invention
All deformations that content is directly exported or associated, are considered as protection scope of the present invention.
Claims (7)
1. a kind of preparation method for the spraying that decays tooth, it is characterised in that comprise the following steps：
(1) in parts by weight, fourth eggplant 3-5 parts, castor bean 10-14 parts, Radix zanthoxyli 8-12 parts, radix glycyrrhizae 8-12 parts, peppermint 10- are taken
14 parts, tealeaves 10-14 parts, clean, dry, then take 30-40 part lards；
(2) other raw materials in addition to lard are slightly dried, adds in lard and be well mixed；
(3) raw material mixed heating is distilled, collects distillate；
(4) it will be packed after distillate pressurization cooling, spray be made.
2. the preparation method of decayed tooth spraying as claimed in claim 1, it is characterised in that：Step (1) is in parts by weight, to take
4 parts of fourth eggplant, 12 parts of castor bean, 10 parts of Radix zanthoxyli, 10 parts of radix glycyrrhizae, 12 parts of peppermint, 12 parts of tealeaves, clean, dry, then take 35 portions of pigs
Oil.
3. the preparation method of decayed tooth spraying as claimed in claim 1, it is characterised in that：Fourth eggplant used is after fourth eggplant seed is dried
The powder being ground into.
4. the preparation method of decayed tooth spraying as claimed in claim 1, it is characterised in that：Slightly drying in step (2) be by
Raw material dries 30-60min at 75-85 DEG C.
5. the preparation method of decayed tooth spraying as claimed in claim 1, it is characterised in that：Distillation in step (3) is to mix
Good raw material heats distillation 4-6h at 200-300 DEG C.
6. the preparation method of decayed tooth spraying as claimed in claim 1, it is characterised in that：Also including step (5) will before use
Spray heats 10-20min at 50-75 DEG C.
7. decayed tooth prepared by the preparation method sprayed by the decayed tooth described in claim 1-6 any one is sprayed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710719361.5A CN107432896A (en) | 2017-08-21 | 2017-08-21 | One kind decayed tooth spraying and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710719361.5A CN107432896A (en) | 2017-08-21 | 2017-08-21 | One kind decayed tooth spraying and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107432896A true CN107432896A (en) | 2017-12-05 |
Family
ID=60460105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710719361.5A Pending CN107432896A (en) | 2017-08-21 | 2017-08-21 | One kind decayed tooth spraying and preparation method thereof |
Country Status (1)
| Country | Link |
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| CN (1) | CN107432896A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5738708A (en) * | 1980-08-18 | 1982-03-03 | Lion Corp | Composition for oral purpose |
| FR2705571A1 (en) * | 1993-05-24 | 1994-12-02 | Perez Adrien Guy | Combination of a fatty oil and one or more aromatic essential oils |
| CN104800109A (en) * | 2015-01-21 | 2015-07-29 | 罗剑 | Siraitia grosvenorii mouthwash |
| CN105193696A (en) * | 2014-06-30 | 2015-12-30 | 王岚 | Caries-prevention toothpaste and preparation method thereof |
-
2017
- 2017-08-21 CN CN201710719361.5A patent/CN107432896A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5738708A (en) * | 1980-08-18 | 1982-03-03 | Lion Corp | Composition for oral purpose |
| FR2705571A1 (en) * | 1993-05-24 | 1994-12-02 | Perez Adrien Guy | Combination of a fatty oil and one or more aromatic essential oils |
| CN105193696A (en) * | 2014-06-30 | 2015-12-30 | 王岚 | Caries-prevention toothpaste and preparation method thereof |
| CN104800109A (en) * | 2015-01-21 | 2015-07-29 | 罗剑 | Siraitia grosvenorii mouthwash |
Non-Patent Citations (1)
| Title |
|---|
| 姚振生等: "《浙江药用植物资源志要》", 31 May 2016, 上海科学技术出版社 * |
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Application publication date: 20171205 |