CN107427564A - 免疫原性/治疗性糖缀合物组合物及其用途 - Google Patents
免疫原性/治疗性糖缀合物组合物及其用途 Download PDFInfo
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| US10980894B2 (en) | 2016-03-29 | 2021-04-20 | Obi Pharma, Inc. | Antibodies, pharmaceutical compositions and methods |
| AU2017239637A1 (en) | 2016-03-29 | 2018-11-15 | Obi Pharma, Inc. | Antibodies, pharmaceutical compositions and methods |
| BR112018071683A2 (pt) * | 2016-04-22 | 2019-02-19 | Obi Pharma, Inc. | método para tratar um câncer de mama, método para tratamento de um tumor em um paciente, método para tratar um indivíduo sofrendo com câncer por imunoterapia, método para induzir/melhorar uma resposta imune em um indivíduo, método para melhorar a vacina obi-822 induzida pela resposta imune em um indivíduo necessitando da mesma, método para identificar um paciente adequado para terapia do câncer e método para determinar o prognóstico do tratamento do câncer ou resposta do fármaco de um paciente |
| WO2018022933A1 (en) * | 2016-07-27 | 2018-02-01 | Obi Pharma, Inc. | Immunogenic/therapeutic glycan compositions and uses thereof |
| US11643456B2 (en) | 2016-07-29 | 2023-05-09 | Obi Pharma, Inc. | Human antibodies, pharmaceutical compositions and methods |
| WO2018094414A1 (en) | 2016-11-21 | 2018-05-24 | Obi Pharma, Inc. | Conjugated biological molecules, pharmaceutical compositions and methods |
| EP3775894B1 (en) * | 2018-05-11 | 2024-04-24 | OBI Pharma, Inc. | Method for predicting human immune response |
| TW202035444A (zh) | 2018-06-27 | 2020-10-01 | 台灣浩鼎生技股份有限公司 | 用於糖蛋白工程的糖苷合成酶變體及其使用方法 |
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|---|---|---|---|---|
| US20040208884A1 (en) * | 1999-08-20 | 2004-10-21 | Danishefsky Samuel J. | Clustered multi-antigenic carbohydrate constructs, methods for their preparation, and uses thereof |
| EP1527081A1 (en) * | 2002-07-31 | 2005-05-04 | Sloan-Kettering Institute For Cancer Research | Glyconjugates comprising carbohydrate epitopes, methods for theirsynthesis, and their use for the treatment or prophylaxis of cancer |
| US20100136042A1 (en) * | 2008-06-16 | 2010-06-03 | Chi-Huey Wong | Globo h and related anti-cancer vaccines with novel glycolipid adjuvants |
| CN102215862A (zh) * | 2009-06-16 | 2011-10-12 | 中央研究院 | Globo h及含新颖糖脂质佐剂的相关抗癌疫苗 |
| US20120237532A1 (en) * | 2011-03-15 | 2012-09-20 | Icon Genetics Gmbh | Pharmaceutical formulation containing immunoglobulin |
| WO2014107652A2 (en) * | 2013-01-04 | 2014-07-10 | Obi Pharma | Vaccines with higher carbohydrate antigen density and novel saponin adjuvant |
| TW201521766A (zh) * | 2013-09-17 | 2015-06-16 | Obi Pharma Inc | 碳水化合物疫苗之化合物及組成物以及其用途 |
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| CA2454853A1 (en) * | 2001-08-14 | 2003-02-27 | Biomira, Inc. | Imunogenic conjugate of carbohydrate haptens and aggregated protein carrier |
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| CA2961522A1 (en) | 2016-03-24 |
| IL251120B (en) | 2021-05-31 |
| TWI726850B (zh) | 2021-05-11 |
| SG11201702037SA (en) | 2017-04-27 |
| TW201628646A (zh) | 2016-08-16 |
| WO2016044326A9 (en) | 2017-05-11 |
| JP2017532310A (ja) | 2017-11-02 |
| EP3193919A4 (en) | 2018-04-18 |
| RU2017112982A (ru) | 2018-10-17 |
| BR112017005120A2 (pt) | 2018-01-23 |
| JP6774941B2 (ja) | 2020-10-28 |
| EP3193919B1 (en) | 2020-04-08 |
| RU2017112982A3 (ja) | 2019-04-24 |
| AU2015317889B2 (en) | 2021-06-03 |
| US20160339089A1 (en) | 2016-11-24 |
| IL251120A0 (en) | 2017-04-30 |
| CL2017000625A1 (es) | 2018-02-02 |
| BR112017005120B1 (pt) | 2021-01-05 |
| ES2797747T3 (es) | 2020-12-03 |
| KR20170090405A (ko) | 2017-08-07 |
| EP3193919A1 (en) | 2017-07-26 |
| PH12017500478A1 (en) | 2017-07-10 |
| MY188880A (en) | 2022-01-12 |
| AR101871A1 (es) | 2017-01-18 |
| AU2015317889A1 (en) | 2017-04-13 |
| KR20230109783A (ko) | 2023-07-20 |
| RU2720295C2 (ru) | 2020-04-28 |
| WO2016044326A1 (en) | 2016-03-24 |
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