CN107405278A8 - 序列为his‑d‑trp‑ala‑trp‑d‑phe‑lys‑nh2的肽用于减少或延缓细胞衰老的出现和皮肤老化的迹象的新型用途 - Google Patents
序列为his‑d‑trp‑ala‑trp‑d‑phe‑lys‑nh2的肽用于减少或延缓细胞衰老的出现和皮肤老化的迹象的新型用途 Download PDFInfo
- Publication number
- CN107405278A8 CN107405278A8 CN201680015792.7A CN201680015792A CN107405278A8 CN 107405278 A8 CN107405278 A8 CN 107405278A8 CN 201680015792 A CN201680015792 A CN 201680015792A CN 107405278 A8 CN107405278 A8 CN 107405278A8
- Authority
- CN
- China
- Prior art keywords
- trp
- aging
- sign
- appearance
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- WZHKXNSOCOQYQX-FUAFALNISA-N (2s)-6-amino-2-[[(2r)-2-[[(2s)-2-[[(2s)-2-[[(2r)-2-[[(2s)-2-amino-3-(1h-imidazol-5-yl)propanoyl]amino]-3-(1h-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1h-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide Chemical group C([C@H](N)C(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCCN)C(N)=O)C1=CN=CN1 WZHKXNSOCOQYQX-FUAFALNISA-N 0.000 title abstract 2
- 230000032677 cell aging Effects 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 230000009759 skin aging Effects 0.000 title abstract 2
- 239000002537 cosmetic Substances 0.000 abstract 2
- 230000003213 activating effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
本发明涉及在生理学上可接受的介质中包含作为活性剂的0.1至1μM的序列为His-D-Trp-Ala-Trp-D-Phe-Lys-NH2的合成肽或其盐之一的组合物用于减少或延缓细胞衰老的出现和皮肤老化的迹象的化妆品用途。本发明还涉及与这些新型用途相关的化妆品处理方法,其包括经至少2天的时段每天至少一次局部施用组合物的步骤。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1553139 | 2015-04-10 | ||
FR1553139A FR3034662B1 (fr) | 2015-04-10 | 2015-04-10 | Nouvelles utilisations du peptide de sequence his-d-trp-ala-trp-d-phe-lys-nh2 pour diminuer ou retarder l'apparition de la senescence cellulaire et des signes du vieillissement cutane |
PCT/EP2016/057813 WO2016162512A1 (fr) | 2015-04-10 | 2016-04-08 | Nouvelles utilisations du peptide de sequence his-d-trp-ala-trp-d-phe-lys-nh2 pour diminuer ou retarder l'apparition de la senescence cellulaire et des signes du vieillissement cutane |
Publications (3)
Publication Number | Publication Date |
---|---|
CN107405278A CN107405278A (zh) | 2017-11-28 |
CN107405278A8 true CN107405278A8 (zh) | 2018-01-12 |
CN107405278B CN107405278B (zh) | 2021-03-30 |
Family
ID=53200208
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201680015792.7A Active CN107405278B (zh) | 2015-04-10 | 2016-04-08 | 序列为his-d-trp-ala-trp-d-phe-lys-nh2的肽用于减少或延缓细胞衰老的出现和皮肤老化的迹象的用途 |
Country Status (7)
Country | Link |
---|---|
US (1) | US11628133B2 (zh) |
EP (1) | EP3280387B1 (zh) |
JP (1) | JP2018513148A (zh) |
KR (1) | KR20170132887A (zh) |
CN (1) | CN107405278B (zh) |
FR (1) | FR3034662B1 (zh) |
WO (1) | WO2016162512A1 (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR3088075A1 (fr) * | 2018-11-06 | 2020-05-08 | Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic | Procede pour evaluer la capacite d'une substance ou d'une composition a prevenir, ralentir ou eliminer les signes du vieillissement de la peau ou des levres |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7429391B2 (en) * | 2004-01-30 | 2008-09-30 | Access Business Group International Llc | Holistic composition and method for reducing skin pigmentation |
KR100962566B1 (ko) * | 2005-10-12 | 2010-06-11 | 주식회사 리제론 | 인간 성장호르몬을 유효성분으로 포함하는 피부 상태 개선용 조성물 |
KR100705981B1 (ko) * | 2005-10-12 | 2007-04-10 | 주식회사 리제론 | 인간 성장호르몬을 포함하는 탈모방지 또는 발모촉진용조성물 |
BRPI0618824A2 (pt) | 2005-11-21 | 2011-09-13 | Univ Miyazaki | agente terapêutico acelerador de recuperação dérmica contendo grelina e derivados desta ou substáncias que atuam sobre ghs-r1a como ingrediente ativo |
CU23592A1 (es) * | 2006-02-28 | 2010-11-11 | Ct Ingenieria Genetica Biotech | Método para prevenir y eliminar las fibrosis y otras formas de depósito patológico en los tejidos aplicando el péptido secretagogo ghrp-6 |
KR20090064743A (ko) * | 2007-12-17 | 2009-06-22 | (주)아모레퍼시픽 | 데아닌을 함유하는 프롤린 리사이클링 촉진용 피부 외용제또는 미용 식품 조성물 |
FR2926720B1 (fr) * | 2008-01-24 | 2011-09-09 | Jean Noel Thorel | Composition cosmetique destinee a bloquer la pigmentation de la peau induite par les rayonnements uv |
JP2010077046A (ja) * | 2008-09-25 | 2010-04-08 | Nikko Seiyaku Kk | エレクトロポレーション用化粧料 |
JP5960505B2 (ja) * | 2011-05-25 | 2016-08-02 | ロート製薬株式会社 | 外用組成物 |
KR101667383B1 (ko) * | 2012-03-28 | 2016-10-18 | 주식회사 인코스팜 | 비오틴이 결합된 hexapeptide-2 유도체 및 이의 용도 |
CN107530270B (zh) * | 2015-03-25 | 2021-08-27 | Gct有限公司 | 化妆品和用于制备该化妆品的浓缩物 |
-
2015
- 2015-04-10 FR FR1553139A patent/FR3034662B1/fr active Active
-
2016
- 2016-04-08 WO PCT/EP2016/057813 patent/WO2016162512A1/fr active Application Filing
- 2016-04-08 US US15/565,226 patent/US11628133B2/en active Active
- 2016-04-08 EP EP16715314.7A patent/EP3280387B1/fr active Active
- 2016-04-08 CN CN201680015792.7A patent/CN107405278B/zh active Active
- 2016-04-08 KR KR1020177032447A patent/KR20170132887A/ko not_active Application Discontinuation
- 2016-04-08 JP JP2017552892A patent/JP2018513148A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
FR3034662A1 (fr) | 2016-10-14 |
CN107405278A (zh) | 2017-11-28 |
US11628133B2 (en) | 2023-04-18 |
EP3280387B1 (fr) | 2019-07-03 |
EP3280387A1 (fr) | 2018-02-14 |
JP2018513148A (ja) | 2018-05-24 |
US20180078483A1 (en) | 2018-03-22 |
WO2016162512A1 (fr) | 2016-10-13 |
CN107405278B (zh) | 2021-03-30 |
KR20170132887A (ko) | 2017-12-04 |
FR3034662B1 (fr) | 2020-08-28 |
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