CN107375877A - A kind of medicine for treating motion sickness and preparation method thereof - Google Patents
A kind of medicine for treating motion sickness and preparation method thereof Download PDFInfo
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- CN107375877A CN107375877A CN201710656011.9A CN201710656011A CN107375877A CN 107375877 A CN107375877 A CN 107375877A CN 201710656011 A CN201710656011 A CN 201710656011A CN 107375877 A CN107375877 A CN 107375877A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/532—Agastache, e.g. giant hyssop
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
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Abstract
The invention discloses a kind of medicine for treating motion sickness.It is by peppermint, flos caryophylli, sweet wormwood, wrinkled giant hyssop, ginger；The auxiliary materials such as vaseline, beeswax are equipped with to be made, be it is a kind of it is curative for effect, have no side effect, technique simply prevents and treats the medicine of motion sickness, and clinical practice is safe and reliable, has no toxic side effect.
Description
Technical field
The present invention relates to the field of Chinese medicines, specifically a kind of medicine for treating motion sickness, the invention further relates to the medicine
Preparation method.
Background technology
Motion sickness is carsick, seasick, airsick and the system by waving, jolting, rotating, the factor associated diseases such as accelerate
Claim.Motion sickness has dizziness, and upper abdomen is uncomfortable, nauseous, cold sweat, or even the symptom such as vomiting；General get off take a momentary rest i.e.
Gradually it can mitigate or recover.This carsick symptom of somebody is also sustainable several days.
The people of motion sickness is susceptible to suffer from, its inner ear balance organ -- vestibular organ adapts to energy to the irregular position chanP such as rotation
Power is poor.Certainly, motion sickness also has other risk factors, such as high temperature, high humidity, improper ventilation, noise, bad gas
Taste, nervous, sleep insufficiency, fatigue, starvation or heavy meal, in poor health etc..
Existing preventing and treating motion sickness uses oral drugs more, predominantly calm antiemetic, such as dramamine, hyoscine, stabilizes
Deng, suppression central excitation, alleviation alimentary canal spasm.But these medicines have effect slowly more, the side effect such as dry, drowsiness, and treat
Imitate undesirable.
Have skin patch after a kind of ear in the prior art, be Anisodus luridus sustained release agent can transdermal flux absorb, but still can not
Eliminate the intrinsic side effect of the medicine.
The content of the invention
The purpose of the present invention is overcome the deficiencies in the prior art, there is provided it is a kind of it is curative for effect, have no side effect, technique it is simple
Prevent and treat medicine of motion sickness and preparation method thereof.
To reach above-mentioned technical purpose, a kind of medicine for treating motion sickness of the present invention, is by the raw material of following parts by weight
Medicine prepares：
40~80 parts of peppermint, 40~80 parts of flos caryophylli, 40~80 parts of sweet wormwood, 120~180 parts of wrinkled giant hyssop, ginger 120~180
Part；It is equipped with auxiliary material：216~360 parts of vaseline, 144~240 parts of beeswax.
Further, the medicine of above-mentioned treatment motion sickness is prepared by the bulk drug of following parts by weight：
60 parts of peppermint, 60 parts of flos caryophylli, 60 parts of sweet wormwood, 150 parts of wrinkled giant hyssop, 150 parts of ginger；It is equipped with auxiliary material：Vaseline 288
Part, 192 parts of beeswax.
The preparation method for the treatment of cinetosis disease drug described above, comprises the following steps：
A, peppermint, flos caryophylli, sweet wormwood, wrinkled giant hyssop, ginger are mixed according to the parts by weight, are ground into more than 100 mesh
Medicinal powder；
B, the vaseline of the parts by weight is melted at 38 DEG C~60 DEG C, adds the beeswax of the parts by weight, add
Temperature be completely melt to 62 DEG C~67 DEG C after, add step a made from medicinal powder, quickly stir, cool down and produce.
In prescription of the present invention, each raw material pharmacology is analyzed as follows：
Peppermint acrid flavour, it is cool in nature.Enter lung, Liver Channel.Dispelling wind and heat from the body, head clearing, relieving sore-throat promoting eruption, soothing the liver promoting the circulation of qi；Flos caryophylli property
It is pungent, taste temperature.Enter lung, spleen, stomach, kidney four to pass through.Effect：Middle benefit gas, warm kidney, drop are inverse.Cure mainly：Control hiccup, vomiting, gastric disorder causing nausea, dysentery, trusted subordinate
Crymodynia, Xuan addictions, hernia, ringworm；Sweet wormwood is bitter, pungent, trembles with fear.Return liver, gallbladder channel, three burnt, kidney channels.Clear abnormal heat, cool blood, which is removed, steams, relieving summer-heat,
Preventing malaria.Generated heat for summer-heat evil, fever due to yin deficiency, night fever abating at dawn, hectic fever due to yin labor heat, malaria fever and chills, jaundice with damp-heat pathogen；Wrinkled giant hyssop is pungent, tepor.Return
Spleen, stomach, lung channel.Driving away summer heat inducing diaphoresis is cured mainly, removing dampness to restore normal functioning of the stomach, is caught a cold for the summertime, fever and chills headache, chest gastral cavity ruffian, vomiting and diarrhea, gestation
Vomiting, nasosinusitis, hand, tinea pedis；The pungent and scattered temperature of ginger, Energy benefit taste, it is apt to middle benefit gas stopping nausea and vomiting by lowering the adverse flow of QI, dehumidify the ruffian that disappears, and cough-relieving apophlegmatic is inverse to drop
Preventing or arresting vomiting is length.All medicine compatibilities, sending down abnormally ascending and stomach, prevent and treat the significant effect of motion sickness.Also heatstroke can be prevented in summer.
Said medicine is made umbilica sticking plaster and used by the present invention, is had the characteristics that compared with prior art：
Beeswax has the effect of inducing astrigency, myogenic, analgesic, removing toxic substances, the great water proofing property of vaseline, is a kind of extraordinary Hydra
Product, for preparing the ointment of medicine and the raw material of skin sparing ointment.Its matrix (auxiliary material) used as umbilica sticking plaster, chemistry
Property it is stable, and the umbilica sticking plaster has the characteristics of main ingredient high volatility, and preparation technology is easy, is advantageous to umbilicus penetrates and absorb,
Especially to, without allergic reaction, more being had no toxic side effect at skin of umbilicus.In addition some oral drugs can be avoided to patient's liver kidney etc.
Produce the bad toxic side effect brought.
Relevant clinical data is as follows：
Case totally 150, male 78, women 72, year at age 7~70 (20.6 ± 2.2)；All it is diagnosed as motion sickness
Shape, previously there is cinetosis symptom history.It is randomly divided into three treatment groups.Three groups of data are poor without conspicuousness in sex, age etc.
Different (P ＞ 0.05), has comparativity.All equal references of case《Otology》In diagnostic criteria and《Tian Shi peaceful cream treatments of swooning are dizzy
92 clinical observations of dynamic disease》The effect of middle criterion is made a definite diagnosis.
Diagnostic criteria：1. the state of mind is normal before riding public transportation means.2. ride public transportation means, occur dizziness headache,
It is excessive saliva, Nausea and vomiting, pale complexion, cold sweat, tired, drowsiness, very then keep vomiting, be uncomfortable in chest, be nervous, cold limbs,
It is brothers' vibration, apathy, One's spirits are drooping.Nausea and vomiting is must have symptom.3. after leaving the vehicles, all diseases of the above alleviate
Or disappear.There is the similar medical history of recurrent exerbation when 4. the past rides public transportation means.
Treatment method：Three groups each 50, receive embodiment 1, embodiment 2, the navel patch clinical treatment of embodiment 3 respectively, carry
Previous hour is affixed on umbilical region.
Efficacy determination：It is effective：It is whole relatively comfortable, no dizziness, Nausea and vomiting symptom, there is obvious appetite；Or only feel gastral cavilty not
Relax, appetite slightly subtracts.Take a turn for the better：Whole process has nausea, but is reduced without vomiting or vomiting number, dizzy, weak, excessive saliva, face
The symptom mitigations such as color is pale, uncomfortable in chest, nervous.It is invalid：Cinetosis symptom is unchanged.
It is as follows to compare statistical result for curative effect after three groups of case treatments：
This medicine does not find toxic side effect through Long-term Clinical Observation, and clinical practice is safe and reliable.
Embodiment
With reference to embodiment, the present invention is further detailed explanation.Description is only used for explaining this hair below
It is bright, it is not intended to limit the present invention.
A kind of medicine for treating motion sickness of the present invention, is prepared by the bulk drug of following parts by weight：
40~80 parts of peppermint, 40~80 parts of flos caryophylli, 40~80 parts of sweet wormwood, 120~180 parts of wrinkled giant hyssop, ginger 120~180
Part；It is equipped with auxiliary material：216~360 parts of vaseline, 144~240 parts of beeswax.
Further, the medicine of above-mentioned treatment motion sickness is prepared by the bulk drug of following parts by weight：
60 parts of peppermint, 60 parts of flos caryophylli, 60 parts of sweet wormwood, 150 parts of wrinkled giant hyssop, 150 parts of ginger；It is equipped with auxiliary material：Vaseline 288
Part, 192 parts of beeswax.
The preparation method for the treatment of cinetosis disease drug described above, comprises the following steps：
A, peppermint, flos caryophylli, sweet wormwood, wrinkled giant hyssop, ginger are mixed according to the parts by weight, are ground into more than 100 mesh
Medicinal powder；
B, the vaseline of the parts by weight is melted at 38 DEG C~60 DEG C, adds the beeswax of the parts by weight, add
After temperature is completely melt to 62 DEG C~67 DEG C, medicinal powder made from addition step a, quickly stirs, cool down and produce.
Technical solution of the present invention is further explained below by section Example：
Embodiment 1：
60 grams of peppermint, 60 grams of flos caryophylli, 60 grams of sweet wormwood, 150 grams of wrinkled giant hyssop, 150 grams of ginger are taken, is mixed after being dried at 35 DEG C
Close, crushing and processing are into medicinal powder more than 100 mesh.
First 288 grams of vaseline are melted at 50 DEG C, add 192 grams of beeswaxs, be heated up to 63 DEG C be completely melt after, add medicine
Powder, quickly stir, cool down.
Umbilica sticking plaster after cooling is inserted in the inner ring of 6cm × 7cm (interior ring size 2cm) non-woven fabrics umbilica sticking plaster cloth pad,
3 grams of dose.The finished product processed is packed with 8cm × 12cm compound membrane bags, one bag of a patch.
Embodiment 2：
40 grams of peppermint, 80 grams of flos caryophylli, 40 grams of sweet wormwood, 180 grams of wrinkled giant hyssop, 120 grams of ginger are taken, is mixed after being dried at 67 DEG C
Close, crushing and processing are into medicinal powder more than 100 mesh.
First 216 grams of vaseline are melted at 60 DEG C, add 144 grams of beeswaxs, be heated up to 65 DEG C be completely melt after, add medicine
Powder, quickly stir, cool down.
Umbilica sticking plaster after cooling is inserted to the inner ring of 7cm × 8cm (interior ring size is 2.5cm) non-woven fabrics umbilica sticking plaster cloth pad
Interior, dose is 2.9 grams.The finished product processed is packed with 8cm × 12cm compound membrane bags, one bag of a patch.
Embodiment 3：
80 grams of peppermint, 40 grams of flos caryophylli, 80 grams of sweet wormwood, 120 grams of wrinkled giant hyssop, 180 grams of ginger are taken, is mixed after being dried at 50 DEG C
Close, crushing and processing are into medicinal powder more than 100 mesh.
First 360 grams of vaseline are melted at 38 DEG C, add 240 grams of beeswaxs, be heated up to 62 DEG C be completely melt after, add medicine
Powder, quickly stir, cool down.
Umbilica sticking plaster after cooling is inserted to the inner ring of 7cm × 8cm (interior ring size is 2.5cm) non-woven fabrics umbilica sticking plaster cloth pad
Interior, dose is 3.1 grams.The finished product processed is packed with 8cm × 12cm compound membrane bags, one bag of a patch.
Only with section Example, the present invention will be described above, does not form any limitation of the invention, all at this
Any modification, improvement and equivalent substitution made in the spirit and principle of invention etc., should be included in protection scope of the present invention
Within.
Claims (3)
1. a kind of medicine for treating motion sickness, it is characterised in that prepared by the bulk drug of following parts by weight：
40~80 parts of peppermint, 40~80 parts of flos caryophylli, 40~80 parts of sweet wormwood, 120~180 parts of wrinkled giant hyssop, 120~180 parts of ginger；Match somebody with somebody
With auxiliary material：216~360 parts of vaseline, 144~240 parts of beeswax.
2. the medicine of motion sickness is treated according to claim 1, it is characterised in that prepared by the bulk drug of following parts by weight
Obtain：
60 parts of peppermint, 60 parts of flos caryophylli, 60 parts of sweet wormwood, 150 parts of wrinkled giant hyssop, 150 parts of ginger；It is equipped with auxiliary material：288 parts of vaseline, honeybee
192 parts of wax.
3. the preparation method of cinetosis disease drug is treated according to claim 1, it is characterised in that comprise the following steps：
A, peppermint, flos caryophylli, sweet wormwood, wrinkled giant hyssop, ginger are mixed according to the parts by weight, the medicinal powder being ground into more than 100 mesh；
B, the vaseline of the parts by weight is melted at 38 DEG C~60 DEG C, adds the beeswax of the parts by weight, be heated up to
After 62 DEG C~67 DEG C are completely melt, medicinal powder made from addition step a, quickly stir, cool down and produce.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710656011.9A CN107375877A (en) | 2017-07-30 | 2017-07-30 | A kind of medicine for treating motion sickness and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710656011.9A CN107375877A (en) | 2017-07-30 | 2017-07-30 | A kind of medicine for treating motion sickness and preparation method thereof |
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| Publication Number | Publication Date |
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| CN107375877A true CN107375877A (en) | 2017-11-24 |
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| CN201710656011.9A Pending CN107375877A (en) | 2017-07-30 | 2017-07-30 | A kind of medicine for treating motion sickness and preparation method thereof |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102847107A (en) * | 2012-08-28 | 2013-01-02 | 赵爱良 | Navel-applied plaster for kinesia and preparation method thereof |
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2017
- 2017-07-30 CN CN201710656011.9A patent/CN107375877A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102847107A (en) * | 2012-08-28 | 2013-01-02 | 赵爱良 | Navel-applied plaster for kinesia and preparation method thereof |
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Application publication date: 20171124 |
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