CN108452261A - It is a kind of to rule the pharmaceutical composition and preparation method for treating cervical spondylosis by law based on hot salt - Google Patents

Abstract

The present invention provides a kind of ruled by law based on hot salt to treat the pharmaceutical composition of cervical spondylosis, including sea salt and traditional Chinese medicinal components, wherein the traditional Chinese medicinal components include the ingredient of following parts by weight：5 15 parts of Radix Angelicae Sinensis, 5 15 parts of safflower, 5 15 parts of Rhizoma Chuanxiong, 5 15 parts of Radix Paeoniae Alba, 5 15 parts of cassia twig, 5 15 parts of fructus viticis, 5 15 parts of Rhizoma Et Radix Notopterygii, 5 15 parts of Radix Angelicae Pubescentis, 5 15 parts of chrysanthemum, 5 15 parts of myrrh, windproof 5 15 parts, 5 15 parts of wilsonii, 5 15 parts of grass-leaved sweetflag, 5 15 parts of turmeric, 5 15 parts of menthol, 5 15 parts of borneol；The weight ratio of the sea salt and traditional Chinese medicinal components is 38:5.Pharmaceutical composition each component scientific compatibility of the present invention, interaction, can effective promoting blood circulation, promoting qi circulation and relieving pain, dispelling wind and eliminating dampness, strengthening the muscles and bones, reach treatment cervical spondylosis the effect of.

Description

It is a kind of to rule the pharmaceutical composition and preparation method for treating cervical spondylosis by law based on hot salt

Technical field

The invention belongs to Chinese medicine preparation technical fields, relate generally to a kind of pharmaceutical composition ruled by law based on hot salt and treat cervical spondylosis Object and preparation method.

Background technology

Cervical spondylosis is common clinical, and according to the literature, illness rate is up to 7%-10%.With the development of society, neck Ascendant trend, and morbidity crowd's rejuvenation, high recurrence rate year by year is presented in vertebra patient, causes to seriously affect to minimal invasive treatment, because This is more and more paid attention to by society and medical field.Cervical spondylosis is starting stage and the base state of cervical spondylosis, clinical table The pain increased now based on cervical pain, when incidence activity, is often accompanied by Wry Neck, checks that visible head is tilted to Ipsilateral When, cervical muscle is nervous and limitation of activity, while neck often has some apparent tender points.Treatment cervical spondylosis mainly has operation and No operation Two kinds of therapies, operative treatment is costly because its difficulty is big, and risk is high, and patient acceptance is low, and clinical application is less.At present more Praise highly non-operative treatment, wherein external treatment of traditional Chinese medicine treats cervical spondylosis safe operation, curative for effect, is increasingly believed by patient Rely.But the general administering mode of external treatment of traditional Chinese medicine is still traditional ointment plaster, and drug absorption infiltration is slow, takes effect slowly.Chinese medicine Package method, Gu claim medicine to press method,《The Yellow Emperor's Canon of Internal Medicine》In on the books, significant effect；It uses till today, which evolves into the thermotherapy of Chinese medicine Method, wherein especially with hot salt method it is easy to use, effect is good.

The patent application of publication number CN104623520A proposes a kind of salt packet and preparation method thereof for treating cervical spondylosis, institute It states and is filled in salt packet with crude salt, it is characterised in that：It is also equipped with the root of Dahurain angelica, Rhizoma Chuanxiong, the root of Chinese clematis, monkshood, radix aconiti agrestis, ginger in the salt packet Each equivalent of Huang, safflower, pueraria lobata.All medicines in formula are heated in salt packet together with salt, spreads at patients with cervical, has heat to cervical vertebra Treatment acts on.But the compounding between the Chinese medicine composition each component of the patent application is to the therapeutic effect unobvious of cervical spondylosis, and patient is not It can obtain the effective treatment.

Invention content

The present invention is directed to deficiencies of the prior art, overcomes the curative effect present in Chinese medicine composition in traditional salt packet Problem, provides a kind of quick, curative effect really, and pharmaceutical composition and its preparation side of cervical spondylosis are treated in the hot salt ruling by law of few side effects Method.

The present invention also provides a kind of salt packets for ruling treatment cervical spondylosis by law based on hot salt, including aforementioned pharmaceutical compositions, hot compress can Significantly alleviate cervical vertebra disease symptoms, it is easy to use.

Technical solution provided by the invention is as follows：

A kind of to rule the pharmaceutical composition for treating cervical spondylosis by law based on hot salt, described pharmaceutical composition includes sea salt and Chinese medicine group Point, wherein the traditional Chinese medicinal components include the ingredient of following parts by weight：

5-15 parts of Radix Angelicae Sinensis, 5-15 parts of safflower, 5-15 parts of Rhizoma Chuanxiong, 5-15 parts of Radix Paeoniae Alba, 5-15 parts of cassia twig, 5-15 parts of fructus viticis, 5-15 parts of Rhizoma Et Radix Notopterygii, 5-15 parts of Radix Angelicae Pubescentis, 5-15 parts of chrysanthemum, 5-15 parts of myrrh is 5-15 parts windproof, 5-15 parts of wilsonii, grass-leaved sweetflag 5- 15 parts, 5-15 parts of turmeric, 5-15 parts of menthol, 5-15 parts of borneol；

The weight ratio of the sea salt and traditional Chinese medicinal components is 3-8:5.

Preferably, the traditional Chinese medicinal components comprise the following components in parts by weight：

5-15 parts of Radix Angelicae Sinensis, 5-15 parts of safflower, 5-15 parts of Rhizoma Chuanxiong, 5-15 parts of Radix Paeoniae Alba, 5-15 parts of cassia twig, 5-15 parts of fructus viticis, 5-15 parts of Rhizoma Et Radix Notopterygii, 5-15 parts of Radix Angelicae Pubescentis, 5-15 parts of chrysanthemum, 5-15 parts of myrrh is 5-15 parts windproof, 5-15 parts of wilsonii, grass-leaved sweetflag 5- 15 parts, 5-15 parts of turmeric, 5-15 parts of menthol, 5-15 parts of borneol.

Preferably, the traditional Chinese medicinal components include the ingredient of following parts by weight：5-7 parts of Radix Angelicae Sinensis, 5-7 parts of safflower, Rhizoma Chuanxiong 5-7 Part, 5-7 parts of Radix Paeoniae Alba, 5-7 parts of cassia twig, 5-7 parts of fructus viticis, 5-7 parts of Rhizoma Et Radix Notopterygii, 5-7 parts of Radix Angelicae Pubescentis, 5-7 parts of chrysanthemum, 5-7 parts of myrrh, It is 5-7 parts windproof, 5-7 parts of wilsonii, 5-7 parts of grass-leaved sweetflag, 5-7 parts of turmeric, 5-7 parts of menthol, 5-7 parts of borneol；

The weight ratio of the sea salt and traditional Chinese medicinal components is 1:1.

Following basis《Chinese Pharmacopoeia》、《Dictionary of medicinal plant》And《Chinese draft》It introduces the nature and flavor of primary raw material medicine, return Through basic conditions such as, function and applications.

Radix Angelicae Sinensis：It is sweet in flavor, pungent, warm-natured, Return liver, the heart, the spleen channel；It enriches blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation.It is all for the deficiency of blood Card, irregular menstruation, Amenorrhea, dysmenorrhoea, abdominal mass knot are poly-, uterine bleeding, asthenia cold abdominalgia, Impotence numbness, numbness, intestines are dry and shit is difficult, weight after dysentery characterized by blood in the stool, Ulcer sores, injury from falling down.

Safflower：Acrid flavour, warm-natured, converge to heart and liver channels；Gas perfume (or spice) row dissipates, invigorate blood circulation, stasis-dispelling and pain-killing.For Amenorrhea, dysmenorrhoea is disliked Reveal not all right, abdominal mass lump in the abdomen, chest impediment and cardialgia, stasis of blood, chest side of body shouting pain, injury from falling down, sore swell and ache curative.

Rhizoma Chuanxiong：Acrid flavour, warm-natured, Return liver, courage, the heart channel of Hang-Shaoyin；Promote breath and open depression, method wind-dryness is wet, promoting blood circulation and stopping pain.It is revolved for air-cooled headache It is dizzy, hypochondriac pain abdomen pain, arthritis muscle contraction, Amenorrhea, difficult labour, postpartum stasis block pain, ulcer sores.

Radix Paeoniae Alba：Bitter, acid, cold nature, Return liver, the spleen channel；Nourishing blood for regulating menstruation, astringing YIN to stop sweating, soft liver analgesic, suppressing liver-YANG.With In irregular menstruation, dysmenorrhea, the diseases such as uterine bleeding and spontaneous perspiration, night sweat.

Cassia twig：Acrid flavour, sweet, warm-natured, return lung, the heart, bladder warp；Sweating expelling pathogenic factors from muscles and skin, warming meridian, helps yang transforming qi.For chill Flu, coldness and pain in the epigastrium, blood trembles with fear Amenorrhea, joint pain, phlegm and retained fluid, oedema, palpitaition, run quickly globefish.

Fructus viticis：Acrid flavour, hardship, cool in nature, Return liver, stomach, bladder warp；Dispelling wind and heat from the body, head clearing, joint at dehumidifying.For Exogenous headache, polarization intermittent headache, the mesh that swoons is dark, many tear of red eyes, pain, gingivitis, arthritis with fixed pain caused by dampness contraction in mesh eyeball.

Rhizoma Et Radix Notopterygii：Acrid flavour, hardship, it is warm-natured, return bladder, kidney channel；Relieving exterior syndrome and dispelling cold, expelling wind and eliminating dampness, analgesic.For anemofrigid cold, wind Cold-dampness numbness, item strengthening tendons are anxious, joint ache, geomantic omen edema, skin sore.

Radix Angelicae Pubescentis：Acrid flavour, hardship, slightly warm in nature return kidney, bladder warp；Dispelling wind and eliminating dampness, arthritis analgesic.For wind-cold-dampness arthralgia, pain is washed Bitterly, few the moon volt wind headache, chill hold wet headache under the arm.

Chrysanthemum：Bitter, sweet, cold nature, return lung, Liver Channel；Relieve heat heat-clearing, flat liver improving eyesight are clearing heat and detoxicating.For wind-heat sense It emits, dizziness of having a headache, red eye, swell pain, eyes is dim-sighted, sore and toxic.

Myrrh：Acrid flavour, hardship, mild-natured, the thoughts of returning home, liver, the spleen channel；Scattered stasis pain, detumescence and promoting granulation.For chest impediment and cardialgia, pain of gastric cavity Bitterly, dysmenorrhoea Amenorrhea, postpartum stasis , Disorder lump in the abdomen is suffered from abdominal pain, arthralgia pain due to rheumatism, traumatic injury, the treatment of the illnesss such as carbuncle swells sore.

It is windproof：Acrid flavour, sweet, slightly warm in nature, return bladder, lung, spleen, Liver Channel；It expels pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, relieving convulsion.For diseases caused by external factors Exterior syndrome, rubella itch, arthralgia pain due to rheumatism, lockjaw just, the insufficiency of the spleen with overabundance of dampness.

Wilsonii：Acrid flavour, slight bitter, warm-natured, returns spleen, kidney, the heart channel of Hang-Shaoyin；It replenishes qi to invigorate the spleen, tonifies the kidney to relieve mental strain.For the insufficiency of both the spleen and the kindey, body It is empty weak, loss of appetite, soreness of waist and knee joint, insomnia and dreamful sleep.

Grass-leaved sweetflag：Acrid flavour, it is warm-natured, return stomach, the heart channel of Hang-Shaoyin；Have one's ideas straightened out and allays excitement, removing dampness to restore normal functioning of the stomach.It is delirious for heart spirit confused by phlegm, Coma due to blocking of the respiratory system, forgetful, tinnitus, deaf, it is bored that chest and abdomen are swollen, a mouthful fulminant dysentery of keeping silent, wind-cold-dampness arthralgia.

Turmeric：Acrid flavour, hardship, warm-natured, returns spleen, Liver Channel；Blood-breaking, promoting the circulation of qi, promoting menstruation, analgesic.For trusted subordinate's feeling of fullness distending pain, arm Bitterly, abdominal mass, women's blood stasis, the postpartum stasis of blood stop abdominal pain, injury from falling down, carbuncle swells.

Menthol：Acrid flavour, cool in nature, return lung, Liver Channel；Dissipate wind-heat, refresh oneself, throat, promoting eruption, Xie Yu.For mesh of having a headache It is red, abscess of throat, measles without adequate eruption.

Borneol：Acrid flavour, hardship, cold nature, the thoughts of returning home, spleen, lung channel；Delicate fragrance a surname dissipate has inducing resuscitation of having one's ideas straightened out, heat-clearing dissipates poison, improving eyesight The effect of moving back screen.For high fever apoplexy coma due to blocking of the respiratory system shies epilepsy, apoplexy coma due to blocking of the respiratory system shies epilepsy, summer-heat and damp blinds clear key, throat deafness, aphtha tooth swells, sore carbuncle Infantile malnutrition due to digestive disturbances or intestinalparasites hemorrhoid, red eye, swell pain, pterygium.

Sea salt：Taste is salty, cold in nature, returns stomach, kidney, large intestine, small intestinl channel；Logical product of spitting, cool blood of relieving inflammation or internal heat, priming return kidney.

Preferably, the sea salt grain size is 1-2mm.

A method of preparing the pharmaceutical composition for ruling treatment cervical spondylosis by law based on hot salt, including following preparation step Suddenly：

S1. Radix Angelicae Sinensis is weighed by weight, safflower, Rhizoma Chuanxiong, Radix Paeoniae Alba, cassia twig, fructus viticis, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, chrysanthemum, myrrh prevents Wind, wilsonii, grass-leaved sweetflag, turmeric, menthol, borneol, and crushed, then sieve with 100 mesh sieve to obtain drug powder；

S2. drug powder obtained above and sea salt are uniformly mixed, is drying to obtain.

Further, the present invention also provides a kind of, and being ruled by law based on hot salt comprising aforementioned pharmaceutical compositions treats the salt of cervical spondylosis Packet.

It is compared with the prior art, beneficial effects of the present invention：

Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving；Safflower is promoting blood circulation and removing blood stasis, dissipate wet effect going to swell；Rhizoma Chuanxiong have blood and dissolving stasis, promote breath and open depression, Wind-expelling pain-stopping；Radix Paeoniae Alba has nourishing blood for regulating menstruation, astringing YIN to stop sweating, soft liver analgesic, suppressing liver-YANG and other effects；Cassia twig is to cure mainly interior cold to commonly use Drugs for dispelling internal cold, have complement sun, promoting blood circulation, warming spleen and stomach the effect of；Fructus viticis can ease pain, is anti-inflammatory；Rhizoma Et Radix Notopterygii dissipates exterior cold, wind-damp dispelling, Sharp joint, analgesic；Radix Angelicae Pubescentis expelling wind and eliminating dampness, eliminating cold to stop pain；Chrysanthemum have dispelling wind, soothing the liver work(, smell it, have auxiliary treatment work to pain With；Myrrh dissipates blood stasis eliminatings, detumescence ding-tong；It is windproof to expel pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, relieving convulsion；Wilsonii has bowl spares strengthening the essence, hard muscle The effect of bone, strong will；Grass-leaved sweetflag perfume (or spice) is had one's ideas straightened out, and is gone by phlegm turbid, has effects that calmness, stomach invigorating, analgesia；Turmeric promoting the circulation of qi is stagnant, relieve heat It invigorates blood circulation and eases pain；Menthol dispelling wind and heat from the body, it acts as anti-inflammatory, analgesia, stomach invigorating wind-dispelling, antipruritic；Borneol resuscitation with aromatics, heat dissipation stop Bitterly.

The present invention provides the combinations of above-mentioned Chinese medicine, Chinese medicine each component scientific compatibility, and interaction can be effective Promoting blood circulation and removing blood stasis, promoting qi circulation and relieving pain, dispelling wind and eliminating dampness, strengthening the muscles and bones, and accelerate drug locally to import by hot salt, promote local blood to follow Ring improves the permeability of cell, absorbs local swelling exudate, to play promoting blood circulation and removing blood stasis, anti-inflammatory analgetic, promote cell repair Effect, cervical spondylosis related symptoms can be effectively relieved.

Specific implementation mode

In order to make the purpose , technical scheme and advantage of the present invention be clearer, below in conjunction with specific embodiment, to this Invention be further described, but the present invention claims protection domain be not limited to embodiment.

Sea salt grain size used by following embodiment and comparative examples is 1-2mm.

Embodiment 1:Prepare the salt packet ruled by law based on hot salt and treat cervical spondylosis

Formula：Radix Angelicae Sinensis 5Kg, safflower 5Kg, Rhizoma Chuanxiong 5Kg, Radix Paeoniae Alba 5Kg, cassia twig 5Kg, fructus viticis 5Kg, Rhizoma Et Radix Notopterygii 5Kg, Radix Angelicae Pubescentis 5Kg, chrysanthemum 5Kg, myrrh 5Kg, windproof 5Kg, wilsonii 5Kg, grass-leaved sweetflag 5Kg, turmeric 5Kg, menthol 5Kg, borneol 5Kg.

Preparation method：S1. Radix Angelicae Sinensis, safflower, Rhizoma Chuanxiong, Radix Paeoniae Alba, cassia twig, fructus viticis, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, chrysanthemum are taken by above-mentioned weight Flower, myrrh is windproof, wilsonii, grass-leaved sweetflag, turmeric, menthol, ten Six-element pulverizing medicinal materials of borneol, and sieves with 100 mesh sieve to obtain drug powder End；S2. by drug powder obtained above and sea salt by weight 5:3 uniformly mixing, it is dry in vacuum desiccator, it prepares At powder；S3. powder is placed in pure cotton cloth bag, is packed.

Embodiment 2:Prepare the salt packet ruled by law based on hot salt and treat cervical spondylosis

Formula：Radix Angelicae Sinensis 9Kg, safflower 10Kg, Rhizoma Chuanxiong 7Kg, Radix Paeoniae Alba 12Kg, cassia twig 5Kg, fructus viticis 15Kg, Rhizoma Et Radix Notopterygii 8Kg, solely 8Kg living, chrysanthemum 9Kg, myrrh 11Kg, windproof 15Kg, wilsonii 6Kg, grass-leaved sweetflag 5Kg, turmeric 15Kg, menthol 5Kg, borneol 5Kg。

Preparation method：S1. Radix Angelicae Sinensis, safflower, Rhizoma Chuanxiong, Radix Paeoniae Alba, cassia twig, fructus viticis, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, chrysanthemum are taken by above-mentioned weight Flower, myrrh is windproof, wilsonii, grass-leaved sweetflag, turmeric, menthol, ten Six-element pulverizing medicinal materials of borneol, and sieves with 100 mesh sieve to obtain drug powder End；S2. by drug powder obtained above and sea salt by weight 5:4 uniformly mixing, it is dry in vacuum desiccator, it prepares At powder；S3. powder is placed in pure cotton cloth bag, is packed.

Embodiment 3:Prepare the salt packet ruled by law based on hot salt and treat cervical spondylosis

Formula：Radix Angelicae Sinensis 5Kg, safflower 5Kg, Rhizoma Chuanxiong 5Kg, Radix Paeoniae Alba 5Kg, cassia twig 5Kg, fructus viticis 5Kg, Rhizoma Et Radix Notopterygii 5Kg, Radix Angelicae Pubescentis 5Kg, chrysanthemum 5Kg, myrrh 5Kg, windproof 5Kg, wilsonii 5Kg, grass-leaved sweetflag 5Kg, turmeric 5Kg, menthol 5Kg, borneol 5Kg.

Preparation method：S1. Radix Angelicae Sinensis, safflower, Rhizoma Chuanxiong, Radix Paeoniae Alba, cassia twig, fructus viticis, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, chrysanthemum are taken by above-mentioned weight Flower, myrrh is windproof, wilsonii, grass-leaved sweetflag, turmeric, menthol, ten Six-element pulverizing medicinal materials of borneol, and sieves with 100 mesh sieve to obtain drug powder End；S2. by drug powder obtained above and sea salt by weight 1:1 uniformly mixing, it is dry in vacuum desiccator, it prepares At powder；S3. powder is placed in pure cotton cloth bag, is packed.

Embodiment 4:Prepare the salt packet ruled by law based on hot salt and treat cervical spondylosis

Formula：Radix Angelicae Sinensis 7Kg, safflower 5Kg, Rhizoma Chuanxiong 7Kg, Radix Paeoniae Alba 5Kg, cassia twig 7Kg, fructus viticis 5Kg, Rhizoma Et Radix Notopterygii 5Kg, Radix Angelicae Pubescentis 7Kg, chrysanthemum 7Kg, myrrh 5Kg, windproof 7Kg, wilsonii 5Kg, grass-leaved sweetflag 5Kg, turmeric 7Kg, menthol 5Kg, borneol 5Kg.

Preparation method：S1. Radix Angelicae Sinensis, safflower, Rhizoma Chuanxiong, Radix Paeoniae Alba, cassia twig, fructus viticis, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, chrysanthemum are taken by above-mentioned weight Flower, myrrh is windproof, wilsonii, grass-leaved sweetflag, turmeric, menthol, ten Six-element pulverizing medicinal materials of borneol, and sieves with 100 mesh sieve to obtain drug powder End；S2. by drug powder obtained above and sea salt by weight 5:8 uniformly mixing, it is dry in vacuum desiccator, it prepares At powder；S3. powder is placed in pure cotton cloth bag, is packed.

Comparative example 1:

Compared with Example 3, other conditions are identical, and only drug powder and sea salt are by weight 3:1.

Comparative example 2:

Compared with Example 3, other conditions are identical, and only drug powder and sea salt are by weight 5:12.

Comparative example 3:

Compared with Example 3, it is added without sea salt, other conditions are identical.

Comparative example 4:

Compared with Example 3, formula only has sea salt not have traditional Chinese medicinal components, other conditions identical.

Comparative example 5：

Compared with Example 3, formula is identical, and preparation method is as follows：

S1. Radix Angelicae Sinensis is taken by above-mentioned weight, safflower, Rhizoma Chuanxiong, Radix Paeoniae Alba, cassia twig, fructus viticis, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, chrysanthemum, myrrh prevents Wind, wilsonii, grass-leaved sweetflag, turmeric, menthol, ten Six-element pulverizing medicinal materials of borneol, and cross 40 mesh and sieve to obtain drug powder；It S2. will be upper The drug powder and sea salt stated are by weight 1:1 uniformly mixing, it is dry in vacuum desiccator, it is prepared into powder；S3. will Powder is placed in pure cotton cloth bag, is packed.

Clinical test case

Clinical test is carried out to 1-4 of the embodiment of the present invention and comparative example 1-5 the salt packet prepared, it is specific as follows：

One, experiment sample

Selecting 360 patients, 360 patients are in August, 2015~2016 year December medical cervical spondylosis patients, Diseased region is without skin injury, and x-ray penetrates piece and excludes bone lesion.Wherein man 190, female 170, age are 21 years old -57 Between year.It is divided into 9 groups each 40 by random digits table.

Above-mentioned patient meets following standard：1. meeting the diagnostic criteria -8J of cervical spondylosis, there is typical cervical spondylosis clinical Symptom, such as Chinese medicine qi depression to blood stasis or the clinical symptoms of kidney deficiency and liver；2. imaging diagnosis is corresponding with clinical manifestation；3. cervical vertebra Dysfunction, i.e. cervical functional impairment index (the neck disability index, NDI) score 20 points or more；4. year 18~60 years old age；5. subject is voluntary and signs informed consent form.Exclusion criteria：1. cervical trauma, fracture or history of operation, nerve Functional impairment, cervical vertebra, neck soft and other illness, congenital vertebra exception, systemic bone or joint disease person；2. 1 month It is inscribed to have received cervical spondylosis associated treatment person；3. suffering from other systems serious disease such as cardiovascular and cerebrovascular disease, diabetes, tumour, blood coagulation Functional disorder disease etc. and skin disease or skin have damaged person；4. gestation, women breast-feeding their children；5. cannot coordinate and/or nothing Legal principle solution therapeutic scheme person.

Age, gender, disease degree, the clinical manifestation etc. of above-mentioned 9 groups of patients is statistically analyzed, no significant difference meaning Justice (P>0.05) it, is comparable.

Two, experimental method

Reference《New Chinese medicine treatment cervical spondylosis faces art research guideline》, embodiment is as follows：

(1) patient takes end sitting position or prone position, neck natural relaxation fully to expose skin of neck, trouble is separated with treatment towel Person's clothing avoids pack when treatment from being infected with clothing；

(2) it is applied with：Sizeable pack is selected according to operating position, 60 DEG C is heated to, spreads on neck, the topical application of drug time is about It is 60~120 minutes, 2 times/day, 30 days as one therapeutic course.

Observation index：1. the evaluation of neck functional evaluates patient's neck functional using NDI.The scale includes 10 sides Face：Pain degree, personal nursing lift weight, reading, have a headache, focusing on, working, sleeping, driving and entertaining.Each For score value from 0 point (accessible) to 5 points (complete obstacles), total score is higher, indicates that cervical functional is poorer, highest is divided into 50 points.②VAS Evaluation：0 point painless, 10 points of severe pains.3. adverse reaction situation, such as skin scald.Observation experiment result such as table 1,2 institute of table Show.

Statistical method is for statistical analysis using 19.0 statistical softwares of SPSS.Normal distribution measurement data uses mean ± standard deviation carries out statistics description, and comparison among groups are examined using t.P<0.05 is statistically significant for difference.

The comparison of the pretherapy and post-treatment NDI scale scores of 1 five groups of patients of table

Note：P ＜ 0.05

Continued 1

Note：P ＜ 0.05

The comparison of the pretherapy and post-treatment VAS scorings of 2 five groups of patients of table

Note：P ＜ 0.05

Continued 2

Note：P ＜ 0.05

As shown in table 1, table 2, pretherapy and post-treatment NDI scorings are compared compares with VAS scorings, the treatment of 1-4 of the embodiment of the present invention It is with obvious effects to be better than comparative example 1-5.Comparative example 3,4 is respectively that traditional Chinese medicine ingredients are used alone and sea salt is used alone as drug to match Side, the existing traditional Chinese medicine ingredients that therapeutic effect is substantially less than embodiment 1-4 have the using effect of sea salt again；And in comparative example 1,2, For the mass ratio of traditional Chinese medicine ingredients and sea salt not in the ratio range of the present invention, therapeutic effect is also significantly lower than embodiment 1-4's Therapeutic effect.On the one hand, the content of sea salt is excessive in pharmaceutical composition, then traditional Chinese medicinal components content is very few, cannot effectively volatilize Go out functional component；On the other hand, the content of sea salt is very few in pharmaceutical composition, and heating effect and fever time reduce, together Sample influences traditional Chinese medicinal components and plays effect.Comparative example 5 changes the preparation method of traditional Chinese medicinal components, and traditional Chinese medicinal components grain size is too big, Chinese medicine Component can not effectively volatilize functional component, and therapeutic effect is also significantly lower than the therapeutic effect of embodiment 1-4.It is found that this hair Bright to be ruled by law based on hot salt in the pharmaceutical composition for treating cervical spondylosis, traditional Chinese medicinal components and sea salt scientific compatibility have promoting blood circulation and removing blood stasis, promoting the circulation of qi The effect of analgesic, dispelling wind and eliminating dampness, strengthening the muscles and bones, to alleviate disease symptoms significantly.

According to the disclosure and teachings of the above specification, those skilled in the art in the invention can also be to above-mentioned embodiment party Formula is changed and is changed.Therefore, the invention is not limited in specific implementation modes disclosed and described above, to the one of invention A little modifications and changes should also be as falling into the scope of the claims of the present invention.In addition, although being used in this specification Some specific terms, these terms are merely for convenience of description, does not limit the present invention in any way.

Claims (6)

1. a kind of ruling the pharmaceutical composition for treating cervical spondylosis by law based on hot salt, which is characterized in that described pharmaceutical composition includes sea salt And traditional Chinese medicinal components, wherein the traditional Chinese medicinal components include the ingredient of following parts by weight：

5-15 parts of Radix Angelicae Sinensis, 5-15 parts of safflower, 5-15 parts of Rhizoma Chuanxiong, 5-15 parts of Radix Paeoniae Alba, 5-15 parts of cassia twig, 5-15 parts of fructus viticis, Rhizoma Et Radix Notopterygii 5-15 parts, 5-15 parts of Radix Angelicae Pubescentis, 5-15 parts of chrysanthemum, 5-15 parts of myrrh is 5-15 parts windproof, 5-15 parts of wilsonii, 5-15 parts of grass-leaved sweetflag, 5-15 parts of turmeric, 5-15 parts of menthol, 5-15 parts of borneol；

The weight ratio of the sea salt and traditional Chinese medicinal components is 3-8:5.

2. ruling the pharmaceutical composition for treating cervical spondylosis by law based on hot salt according to claim 1, which is characterized in that the Chinese medicine group Ingredient of the subpackage containing following parts by weight：

5-7 parts of Radix Angelicae Sinensis, 5-7 parts of safflower, 5-7 parts of Rhizoma Chuanxiong, 5-7 parts of Radix Paeoniae Alba, 5-7 parts of cassia twig, 5-7 parts of fructus viticis, 5-7 parts of Rhizoma Et Radix Notopterygii, 5-7 parts of Radix Angelicae Pubescentis, 5-7 parts of chrysanthemum, 5-7 parts of myrrh is 5-7 parts windproof, 5-7 parts of wilsonii, 5-7 parts of grass-leaved sweetflag, and 5-7 parts of turmeric is thin 5-7 parts of lotus brain, 5-7 parts of borneol；

The weight ratio of the sea salt and traditional Chinese medicinal components is 1:1.

3. according to claim 1 or claim 2 rule the pharmaceutical composition for treating cervical spondylosis by law based on hot salt, which is characterized in that the sea Salt grain size is 1-2mm.

4. ruling the pharmaceutical composition for treating cervical spondylosis by law based on hot salt according to claim 1, which is characterized in that the Chinese medicine group Divide and comprises the following components in parts by weight：

5-15 parts of Radix Angelicae Sinensis, 5-15 parts of safflower, 5-15 parts of Rhizoma Chuanxiong, 5-15 parts of Radix Paeoniae Alba, 5-15 parts of cassia twig, 5-15 parts of fructus viticis, Rhizoma Et Radix Notopterygii 5-15 parts, 5-15 parts of Radix Angelicae Pubescentis, 5-15 parts of chrysanthemum, 5-15 parts of myrrh is 5-15 parts windproof, 5-15 parts of wilsonii, 5-15 parts of grass-leaved sweetflag, 5-15 parts of turmeric, 5-15 parts of menthol, 5-15 parts of borneol.

5. rule the preparation method for the pharmaceutical composition for treating cervical spondylosis described in a kind of any one of claim 1-4 by law based on hot salt, Including following preparation process：

S1. Radix Angelicae Sinensis is weighed by weight, safflower, Rhizoma Chuanxiong, Radix Paeoniae Alba, cassia twig, fructus viticis, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, chrysanthemum, myrrh is windproof, Wilsonii, grass-leaved sweetflag, turmeric, menthol, borneol, and crushed, then sieve with 100 mesh sieve to obtain drug powder；

S2. drug powder obtained above and sea salt are uniformly mixed, is drying to obtain.

6. a kind of ruling the salt packet for treating cervical spondylosis by law based on hot salt, which is characterized in that include medicine group as claimed in claim 1 or 2 Close object.