CN107375731A - Treat ointment of body odour and preparation method thereof - Google Patents
Treat ointment of body odour and preparation method thereof Download PDFInfo
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- CN107375731A CN107375731A CN201710548286.0A CN201710548286A CN107375731A CN 107375731 A CN107375731 A CN 107375731A CN 201710548286 A CN201710548286 A CN 201710548286A CN 107375731 A CN107375731 A CN 107375731A
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- ointment
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- body odour
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- 206010040904 Skin odour abnormal Diseases 0.000 title claims abstract description 47
- 239000002674 ointment Substances 0.000 title claims abstract description 42
- 238000002360 preparation method Methods 0.000 title claims abstract description 20
- 244000131316 Panax pseudoginseng Species 0.000 claims abstract description 34
- 244000131522 Citrus pyriformis Species 0.000 claims abstract description 33
- 244000111489 Gardenia augusta Species 0.000 claims abstract description 33
- 235000018958 Gardenia augusta Nutrition 0.000 claims abstract description 33
- 244000241872 Lycium chinense Species 0.000 claims abstract description 33
- 235000015468 Lycium chinense Nutrition 0.000 claims abstract description 33
- 244000124853 Perilla frutescens Species 0.000 claims abstract description 33
- 241001499733 Plantago asiatica Species 0.000 claims abstract description 33
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 33
- 240000004510 Agastache rugosa Species 0.000 claims abstract description 32
- 235000005979 Citrus limon Nutrition 0.000 claims abstract description 32
- 241000218176 Corydalis Species 0.000 claims abstract description 32
- 244000246386 Mentha pulegium Species 0.000 claims abstract description 32
- 235000016257 Mentha pulegium Nutrition 0.000 claims abstract description 32
- 235000004357 Mentha x piperita Nutrition 0.000 claims abstract description 32
- 235000003181 Panax pseudoginseng Nutrition 0.000 claims abstract description 32
- 235000001050 hortel pimenta Nutrition 0.000 claims abstract description 32
- 239000003814 drug Substances 0.000 claims abstract description 28
- 239000004577 thatch Substances 0.000 claims abstract description 26
- HTUMBQDCCIXGCV-UHFFFAOYSA-N lead oxide Chemical compound [O-2].[Pb+2] HTUMBQDCCIXGCV-UHFFFAOYSA-N 0.000 claims abstract description 24
- YEXPOXQUZXUXJW-UHFFFAOYSA-N lead(II) oxide Inorganic materials [Pb]=O YEXPOXQUZXUXJW-UHFFFAOYSA-N 0.000 claims abstract description 24
- 239000000706 filtrate Substances 0.000 claims description 40
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 37
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 22
- 239000000463 material Substances 0.000 claims description 18
- 239000002994 raw material Substances 0.000 claims description 15
- 235000013871 bee wax Nutrition 0.000 claims description 11
- 235000011187 glycerol Nutrition 0.000 claims description 11
- 238000003756 stirring Methods 0.000 claims description 10
- 235000010413 sodium alginate Nutrition 0.000 claims description 8
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 7
- 229940005550 sodium alginate Drugs 0.000 claims description 7
- 239000000661 sodium alginate Substances 0.000 claims description 7
- 239000012166 beeswax Substances 0.000 claims description 4
- 239000011505 plaster Substances 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 24
- 201000010099 disease Diseases 0.000 abstract description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 4
- 229940079593 drug Drugs 0.000 abstract description 4
- 239000000654 additive Substances 0.000 abstract description 3
- 230000000996 additive effect Effects 0.000 abstract description 3
- 239000000203 mixture Substances 0.000 abstract description 3
- 231100000331 toxic Toxicity 0.000 abstract description 3
- 230000002588 toxic effect Effects 0.000 abstract description 3
- 238000004332 deodorization Methods 0.000 abstract description 2
- 238000009472 formulation Methods 0.000 abstract description 2
- 102000004895 Lipoproteins Human genes 0.000 description 10
- 108090001030 Lipoproteins Proteins 0.000 description 10
- CKQVRZJOMJRTOY-UHFFFAOYSA-N octadecanoic acid;propane-1,2,3-triol Chemical compound OCC(O)CO.CCCCCCCCCCCCCCCCCC(O)=O CKQVRZJOMJRTOY-UHFFFAOYSA-N 0.000 description 10
- 241000202807 Glycyrrhiza Species 0.000 description 7
- 238000000034 method Methods 0.000 description 5
- 230000006870 function Effects 0.000 description 4
- 210000000056 organ Anatomy 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 241001530126 Scrophularia Species 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 230000037396 body weight Effects 0.000 description 3
- 231100001252 long-term toxicity Toxicity 0.000 description 3
- 235000019645 odor Nutrition 0.000 description 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 2
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 2
- 235000003140 Panax quinquefolius Nutrition 0.000 description 2
- 238000010171 animal model Methods 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 238000003304 gavage Methods 0.000 description 2
- 235000008434 ginseng Nutrition 0.000 description 2
- 208000002557 hidradenitis Diseases 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000001802 infusion Methods 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 208000026435 phlegm Diseases 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 210000004243 sweat Anatomy 0.000 description 2
- 244000189799 Asimina triloba Species 0.000 description 1
- 235000006264 Asimina triloba Nutrition 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 208000035985 Body Odor Diseases 0.000 description 1
- 206010055000 Bromhidrosis Diseases 0.000 description 1
- 235000009467 Carica papaya Nutrition 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 101000583175 Homo sapiens Prolactin-inducible protein Proteins 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 102100030350 Prolactin-inducible protein Human genes 0.000 description 1
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- 230000005856 abnormality Effects 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 150000004781 alginic acids Chemical class 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 238000002224 dissection Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000002489 hematologic effect Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 239000011812 mixed powder Substances 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 231100000956 nontoxicity Toxicity 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 238000009781 safety test method Methods 0.000 description 1
- 230000009967 tasteless effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000041 toxicology testing Toxicity 0.000 description 1
- 210000001364 upper extremity Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Classifications
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A61K33/24—Heavy metals; Compounds thereof
-
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/532—Agastache, e.g. giant hyssop
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- A61K36/534—Mentha (mint)
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- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
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- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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- A—HUMAN NECESSITIES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A61K36/8964—Anemarrhena
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
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- Medical Informatics (AREA)
- Botany (AREA)
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- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of ointment for treating body odour and preparation method thereof, the ointment includes the Asiatic plantain of 6~10 parts by weight, the lemon peel of 10~18 parts by weight, the fruit of Chinese wolfberry of 3~6 parts by weight, the cape jasmine of 4~7 parts by weight, the radix glycyrrhizae of 3~5 parts by weight, the litharge of 6~12 parts by weight, the radix scrophulariae of 2~4 parts by weight, the corydalis tuber of 6~10 parts by weight, the wind-weed of 2~4 parts by weight, the common perilla stem of 10~15 parts by weight, the wrinkled giant hyssop of 7~13 parts by weight, the pseudo-ginseng of 4~8 parts by weight, the peppermint of 7~15 parts by weight and the spot thatch of 1~2 parts by weight.Inventive formulation combination science, simple, each bulk drug synergy plays the effect of clearing heat and detoxicating qi-regulating deodorization, quick, treats both principal and secondary aspect of disease, has no toxic side effect.Any additive is free of in the formula of the present invention in addition, it is harmless, it is green.
Description
Technical field
The present invention relates to treatment body odour field, more particularly to a kind of plaster for treating body odour and preparation method thereof.
Background technology
Body odour is also known as underarm odor, is a kind of axillary bromidrosis, it is considered that, underarm odor relevant with the pathocrinia of apocrine sweat gland
Smelly mechanism is the hypersecretion sweat because patient's axillary apocrine is too abundant, just discharges the big sweat of skin surface in breast
White, it is sterile tasteless, decomposed soon by armpit humidity position bacterium, send typical acrid odors.
The mode of traditional treatment body odour is to use operation method, and armpit is had into the skin at armpit hair position together with apocrine sweat gland
Excision, the operation method effect is thorough, but operative incision is larger, and the activity of Post operation upper limbs can be somewhat limited；Strike off in addition
Method, suction scrape method, freezing, high-frequency electrical solving skill etc. all there is it is such or such the drawbacks of, it is impossible to thoroughly eradicate.
The content of the invention
In view of this, it is an object of the invention to provide a kind of ointment for treating body odour and preparation method thereof, therapeutic effect is good,
Cure rate is high, Small side effects.
To achieve these goals, the invention provides following technical scheme：
A kind of plaster for treating body odour, include the raw material of following parts by weight：
Preferably, the raw material of following parts by weight is included：
Preferably, in addition to auxiliary material, the parts by weight of the auxiliary material are 150~200 parts.
Preferably, the auxiliary material includes sodium alginate, glycerine, beeswax, single stearic acid glycerine lipoprotein.
Present invention also offers a kind of above-mentioned preparation method for the ointment for treating body odour, comprise the following steps：
By Asiatic plantain, lemon peel, the fruit of Chinese wolfberry, cape jasmine, radix glycyrrhizae, litharge, radix scrophulariae, corydalis tuber, the wind-weed, common perilla stem, wrinkled giant hyssop,
Pseudo-ginseng, peppermint, spot thatch add medicine decocting tank after crushing, and add water for the first time, after stirring, soak 3~5h；To the medicine decocting tank
In second plus water, boil rear slow fire and endure 3~5h, filter, obtain the first filtrate；Add for the third time into the filter residue being filtrated to get
Water, boil rear slow fire and endure 1~2h, filter, obtain the second filtrate；First filtrate and second filtrate are merged, concentration,
The ointment for the body odour that obtains medical treatment.
Preferably, in addition into the material after concentration auxiliary material is added.
Preferably, the first time adds the dosage of water to be the Asiatic plantain, the lemon peel, the fruit of Chinese wolfberry, the Cape jasmine
It is sub, described radix glycyrrhizae, the litharge, the radix scrophulariae, the corydalis tuber, the wind-weed, the common perilla stem, the wrinkled giant hyssop, described
Pseudo-ginseng, the peppermint, 2~3 times of the spot thatch total amount；It is described state second plus the dosage of water be the Asiatic plantain, the lemon
Lemon skin, the fruit of Chinese wolfberry, the cape jasmine, the radix glycyrrhizae, the litharge, the radix scrophulariae, the corydalis tuber, the wind-weed, institute
State common perilla stem, the wrinkled giant hyssop, the pseudo-ginseng, the peppermint, 4~6 times of the spot thatch total amount；The use for stating third time feedwater
Amount is the Asiatic plantain, the lemon peel, the fruit of Chinese wolfberry, the cape jasmine, the radix glycyrrhizae, the litharge, the radix scrophulariae, institute
State corydalis tuber, the wind-weed, the common perilla stem, the wrinkled giant hyssop, the pseudo-ginseng, the peppermint, 2~3 times of the spot thatch total amount.
A kind of ointment for treating body odour provided by the invention and preparation method thereof, the ointment includes 6~10 parts by weight
Asiatic plantain, the lemon peel of 10~18 parts by weight, the fruit of Chinese wolfberry of 3~6 parts by weight, the cape jasmine of 4~7 parts by weight, 3~5
The radix glycyrrhizae of parts by weight, the litharge of 6~12 parts by weight, the radix scrophulariae of 2~4 parts by weight, 6~10 parts by weight prolong recklessly
Rope, the wind-weed of 2~4 parts by weight, the common perilla stem of 10~15 parts by weight, the wrinkled giant hyssop of 7~13 parts by weight, 4~8 parts by weight
Pseudo-ginseng, the peppermint of 7~15 parts by weight and the spot thatch of 1~2 parts by weight.Inventive formulation combination science, simple, each raw material
Medicine, which acts synergistically, plays the effect of clearing heat and detoxicating qi-regulating deodorization, quick, treats both principal and secondary aspect of disease, has no toxic side effect.The other present invention's
Any additive is free of in formula, it is harmless, it is green.
Embodiment
In order to further appreciate that the present invention, the preferred embodiments of the invention are described with reference to embodiment, but
It is it should be appreciated that these descriptions are simply for further explanation the features and advantages of the present invention rather than to patent requirements of the present invention
Limitation.
The invention provides a kind of plaster for treating body odour, include the raw material of following parts by weight：
Formula combination science, simple in above-mentioned technical proposal, each bulk drug synergy plays clearing heat and detoxicating, qi-regulating and removed
Smelly effect, it is quick, treat both principal and secondary aspect of disease, have no toxic side effect.In addition the present invention formula in be free of any additive, to human body without
Evil, it is green.
Asiatic plantain has the effect of diuresis, heat-clearing, improving eyesight, eliminating the phlegm.In the present invention, the parts by weight of Asiatic plantain be 6~
10 parts；In an embodiment of the present invention, the parts by weight of Asiatic plantain are 7~9 parts；In other embodiments, the weight of Asiatic plantain
Number is 7.5~8.5 parts.
Lemon peel has bactericidal action.In the present invention, the parts by weight of lemon peel are 10~18 parts；In the reality of the present invention
Apply in example, the parts by weight of lemon peel are 12~16 parts；In other embodiments, the parts by weight of lemon peel are 13~15 parts.
The fruit of Chinese wolfberry has the effect of nourishing liver and kidney, benefiting shrewd head.In the present invention, the parts by weight of the fruit of Chinese wolfberry are 3~6
Part；In an embodiment of the present invention, the parts by weight of the fruit of Chinese wolfberry are 3.5~5.5 parts；In other embodiments, the weight of the fruit of Chinese wolfberry
It is 4~5 parts to measure number.
Cape jasmine has a heat-clearing, purging intense heat, the effect of cool blood.In the present invention, the parts by weight of cape jasmine are 4~7 parts；In this hair
In bright embodiment, the parts by weight of cape jasmine are 4.5~6.5 parts；In other embodiments, the parts by weight of cape jasmine are 5~6
Part.
Radix glycyrrhizae has the effect of clearing heat and detoxicating, expelling phlegm and arresting coughing, gastral cavity abdomen.In the present invention, the parts by weight of radix glycyrrhizae are 3~5
Part；In an embodiment of the present invention, the parts by weight of radix glycyrrhizae are 3.6~4.5 parts；In other embodiments, the parts by weight of radix glycyrrhizae
Number is 3.8~4.2 parts.
Litharge has eliminating dampness, desinsection, detoxifies, convergence, the effect of anti-corrosion.In the present invention, the parts by weight of litharge
For 6~12 parts；In an embodiment of the present invention, the parts by weight of litharge are 7.5~10.5 parts；In other embodiments, it is close
The parts by weight of top monk are 8~9 parts.
Radix scrophulariae has the effect of clearing heat and cooling blood, nourishing Yin and falling fire, detoxicating and resolving a mass.In the present invention, the parts by weight of radix scrophulariae are 2
~4 parts；In an embodiment of the present invention, the parts by weight of radix scrophulariae are 2.5~3.5 parts；In other embodiments, the weight of radix scrophulariae
Number is 2.8~3.2 parts.
Corydalis tuber has promoting blood circulation, promoting the circulation of qi, the effect of analgesic.In the present invention, the parts by weight of corydalis tuber are 6~10 parts；
In an embodiment of the present invention, the parts by weight of corydalis tuber are 7~9 parts；In other embodiments, the parts by weight of corydalis tuber are
7.5~8.5 parts.
The wind-weed has the effect of clearing heat-fire, nourishing Yin and moistening dryness.In the present invention, the parts by weight of the wind-weed are 2~4 parts；
In embodiments of the invention, the parts by weight of the wind-weed are 2.5~3.5 parts；In other embodiments, the parts by weight of the wind-weed are
2.8~3.2 parts.
Common perilla stem has pleasant the effect of helping digestion, relieving pain.In the present invention, the parts by weight of common perilla stem are 10~15 parts；
In an embodiment of the present invention, the parts by weight of common perilla stem are 11~14 parts；In other embodiments, the parts by weight of common perilla stem
For 12~13 parts.
Wrinkled giant hyssop, which has, eliminates dampness with aromatics, and middle preventing or arresting vomiting, delivers the function of relieving summer-heat.In the present invention, the parts by weight of wrinkled giant hyssop are 7
~13 parts；In an embodiment of the present invention, the parts by weight of wrinkled giant hyssop are 8~12 parts；In other embodiments, the parts by weight of wrinkled giant hyssop
Number is 9~11 parts.
Pseudo-ginseng has dissipate stasis of blood hemostasis, the function of detumescence ding-tong.In the present invention, the parts by weight of pseudo-ginseng are 4~8 parts；
In embodiments of the invention, the parts by weight of pseudo-ginseng are 5~7 parts；In other embodiments, the parts by weight of pseudo-ginseng be 5.5~
6.5 part.
Peppermint has dispelling wind and heat from the body, head clearing, relieving sore-throat promoting eruption, the function of soothing the liver promoting the circulation of qi.In the present invention, the weight of peppermint
It is 7~15 parts to measure number；In an embodiment of the present invention, the parts by weight of peppermint are 9~13 parts；In other embodiments, it is thin
The parts by weight of lotus are 10~12 parts.
Spot thatch has sensible Li Shui, the function that blood-breaking is stimulated the menstrual flow.In the present invention, the parts by weight of spot thatch are 1~2 part；
In embodiments of the invention, the parts by weight of spot thatch are 1.2~1.8 parts；In other embodiments, the parts by weight of spot thatch are
1.4~1.6 parts.
In an embodiment of the present invention, in addition to auxiliary material, the parts by weight of auxiliary material are 150~200 parts.
The addition of auxiliary material can give full play to the effect of each raw material, reach and treat both principal and secondary aspect of disease, the effect that the recurrence after healing can be avoided, and
Auxiliary material is nonirritant, and stability is unlikely to deteriorate well, is not easy to cause human body sensitive.
In an embodiment of the present invention, auxiliary material includes sodium alginate, glycerine, beeswax and single stearic acid glycerine lipoprotein；At it
In his embodiment, sodium alginate, glycerine, the mass ratio of beeswax and single stearic acid glycerine lipoprotein are (0.5~1)：(2~3)：(1.5~
3)：(0.4~0.7).
Present invention also offers a kind of above-mentioned preparation method for the ointment for treating body odour, comprise the following steps：
By Asiatic plantain, lemon peel, the fruit of Chinese wolfberry, cape jasmine, radix glycyrrhizae, litharge, radix scrophulariae, corydalis tuber, the wind-weed, common perilla stem, wrinkled giant hyssop,
Pseudo-ginseng, peppermint, spot thatch add medicine decocting tank after crushing, and add water for the first time, after stirring, soak 3~5h；To the medicine decocting tank
In second plus water, boil rear slow fire and endure 3~5h, filter, obtain the first filtrate；Add for the third time into the filter residue being filtrated to get
Water, boil rear slow fire and endure 1~2h, filter, obtain the second filtrate；First filtrate and second filtrate are merged, concentration,
The ointment for the body odour that obtains medical treatment.
Wherein, Asiatic plantain, lemon peel, the fruit of Chinese wolfberry, cape jasmine, radix glycyrrhizae, litharge, radix scrophulariae, corydalis tuber, the wind-weed, common perilla stem, the leaves of pulse plants
Perfume, pseudo-ginseng, peppermint, spot Mao Jun are same as above, will not be repeated here.
In above-mentioned technical proposal, first soak to be cooked by slow fire again and enable to the drug effect of medicine best, so as to effectively
Body odour is treated, and curative effect is stable, has no side effect, cure rate is high.
In an embodiment of the present invention, in addition into the material after concentration auxiliary material is added.It is same as above in this auxiliary material,
This is repeated no more.
In an embodiment of the present invention, for the first time plus water dosage be Asiatic plantain, lemon peel, the fruit of Chinese wolfberry, cape jasmine, radix glycyrrhizae,
Litharge, radix scrophulariae, corydalis tuber, the wind-weed, common perilla stem, wrinkled giant hyssop, pseudo-ginseng, peppermint, 2~3 times of spot thatch total amount；Second plus the use of water
Amount be Asiatic plantain, lemon peel, the fruit of Chinese wolfberry, cape jasmine, radix glycyrrhizae, litharge, radix scrophulariae, corydalis tuber, the wind-weed, common perilla stem, wrinkled giant hyssop, pseudo-ginseng,
Peppermint, 4~6 times of spot thatch total amount；The dosage of third time feedwater is Asiatic plantain, lemon peel, the fruit of Chinese wolfberry, cape jasmine, radix glycyrrhizae, close top
Monk, radix scrophulariae, corydalis tuber, the wind-weed, common perilla stem, wrinkled giant hyssop, pseudo-ginseng, peppermint, 2~3 times of spot thatch total amount.
In order to further illustrate the present invention, ointment and its system with reference to embodiment to treatment body odour provided by the invention
Preparation Method is described in detail, but they can not be interpreted as into limiting the scope of the present invention.
Raw material used is commercially available in following examples.
Embodiment 1
The ointment for the treatment of body odour includes the raw material of following parts by weight：
7.5 portions of Asiatic plantains, 13 parts of lemon peels, 5 portions of fruits of Chinese wolfberry, 4.5 portions of cape jasmines, 3.8 portions of radix glycyrrhizaes, 6 parts of litharges, 2 parts it is profound
Ginseng, 7.5 parts of corydalis tubers, 2.8 parts of wind-weeds, 12 parts of common perilla stems, 8 portions of wrinkled giant hyssops, 5.5 portions of pseudo-ginseng, 12 portions of peppermints, 1.4 parts of spot thatches,
18.31 parts of sodium alginates, 85.42 parts of glycerine, 54.92 parts of beeswaxs and 21.35 parts of single stearic acid glycerine lipoproteins.
The preparation method of the ointment of body odour is treated, is comprised the following steps：
By Asiatic plantain, lemon peel, the fruit of Chinese wolfberry, cape jasmine, radix glycyrrhizae, litharge, radix scrophulariae, corydalis tuber, the wind-weed, common perilla stem, wrinkled giant hyssop,
Pseudo-ginseng, peppermint, spot thatch add medicine decocting tank after crushing, and add 182 parts of water, after stirring, soak 4h；Into the medicine decocting tank
546 parts of water are added, rear slow fire is boiled and endures 4h, filters, obtains the first filtrate；Add 182 parts of water into the filter residue being filtrated to get, boil
Slow fire endures 1.5h afterwards, filtering, obtains the second filtrate；First filtrate and second filtrate are merged, concentration, obtained medical treatment
The ointment of body odour.
Embodiment 2
The ointment for the treatment of body odour includes the raw material of following parts by weight：
7 portions of Asiatic plantains, 15 parts of lemon peels, 4 portions of fruits of Chinese wolfberry, 5 portions of cape jasmines, 4.2 portions of radix glycyrrhizaes, 12 parts of litharges, 4 parts of radix scrophulariaes, 6
Part corydalis tuber, 2.5 parts of wind-weeds, 11 parts of common perilla stems, 12 portions of wrinkled giant hyssops, 4 portions of pseudo-ginseng, 10 portions of peppermints, 1.2 parts of spot thatches, 18.51 portions of marine algas
Sour sodium, 68.76 parts of glycerine, 55.54 parts of beeswaxs and 17.19 parts of single stearic acid glycerine lipoproteins.
The preparation method of the ointment of body odour is treated, is comprised the following steps：
By Asiatic plantain, lemon peel, the fruit of Chinese wolfberry, cape jasmine, radix glycyrrhizae, litharge, radix scrophulariae, corydalis tuber, the wind-weed, common perilla stem, wrinkled giant hyssop,
Pseudo-ginseng, peppermint, spot thatch add medicine decocting tank after crushing, and add 215.3 part of 8 water, after stirring, soak 5h；Boiled medicine to described
538.45 parts of water are added in tank, rear slow fire is boiled and endures 4h, filters, obtains the first filtrate；Add into the filter residue being filtrated to get
215.38 parts of water, boil rear slow fire and endure 1h, filter, obtain the second filtrate；First filtrate and second filtrate are merged,
Concentration, the ointment for the body odour that obtains medical treatment.
Embodiment 3
The ointment for the treatment of body odour includes the raw material of following parts by weight：
6 portions of Asiatic plantains, 12 parts of lemon peels, 3.5 portions of fruits of Chinese wolfberry, 6 portions of cape jasmines, 3.6 portions of radix glycyrrhizaes, 7.5 parts of litharges, 2.8 parts
Radix scrophulariae, 7 parts of corydalis tubers, 2 parts of wind-weeds, 15 parts of common perilla stems, 13 portions of wrinkled giant hyssops, 8 portions of pseudo-ginseng, 15 portions of peppermints, 1.8 parts of spot thatches, 25.08 parts
Sodium alginate, 61.31 parts of glycerine, 66.89 parts of beeswaxs and 16.72 parts of single stearic acid glycerine lipoproteins.
The preparation method of the ointment of body odour is treated, is comprised the following steps：
By Asiatic plantain, lemon peel, the fruit of Chinese wolfberry, cape jasmine, radix glycyrrhizae, litharge, radix scrophulariae, corydalis tuber, the wind-weed, common perilla stem, wrinkled giant hyssop,
Pseudo-ginseng, peppermint, spot thatch add medicine decocting tank after crushing, and add 247.68 parts of water, after stirring, soak 4h；Boiled medicine to described
412.8 parts of water are added in tank, rear slow fire is boiled and endures 4h, filters, obtains the first filtrate；Add 309.6 into the filter residue being filtrated to get
Part water, boils rear slow fire and endures 1.5h, filters, obtains the second filtrate；First filtrate and second filtrate are merged, be dense
Contracting, the ointment for the body odour that obtains medical treatment.
Embodiment 4
The ointment for the treatment of body odour includes the raw material of following parts by weight：
9 portions of Asiatic plantains, 16 parts of lemon peels, 5.5 portions of fruits of Chinese wolfberry, 6.5 portions of cape jasmines, 4.5 portions of radix glycyrrhizaes, 10.5 parts of litharges, 3.2
Part radix scrophulariae, 10 parts of corydalis tubers, 4 parts of wind-weeds, 14 parts of common perilla stems, 12 portions of wrinkled giant hyssops, 5 portions of pseudo-ginseng, 7 portions of peppermints, 1.6 parts of spot thatches, 13.64
Part sodium alginate, 81.81 parts of glycerine, 40.91 parts of beeswaxs and 13.64 parts of single stearic acid glycerine lipoproteins.
The preparation method of the ointment of body odour is treated, is comprised the following steps：
By Asiatic plantain, lemon peel, the fruit of Chinese wolfberry, cape jasmine, radix glycyrrhizae, litharge, radix scrophulariae, corydalis tuber, the wind-weed, common perilla stem, wrinkled giant hyssop,
Pseudo-ginseng, peppermint, spot thatch add medicine decocting tank after crushing, and add 282.88 parts of water, after stirring, soak 5h；Boiled medicine to described
489.6 parts of water are added in tank, rear slow fire is boiled and endures 3h, filters, obtains the first filtrate；Add 282.88 into the filter residue being filtrated to get
Part water, boils rear slow fire and endures 1h, filters, obtains the second filtrate；First filtrate and second filtrate are merged, concentration,
The ointment for the body odour that obtains medical treatment.
Embodiment 5
The ointment for the treatment of body odour includes the raw material of following parts by weight：
10 portions of Asiatic plantains, 10 parts of lemon peels, 3 portions of fruits of Chinese wolfberry, 4 portions of cape jasmines, 3 portions of radix glycyrrhizaes, 8 parts of litharges, 2.5 parts of radix scrophulariaes, 9
Part corydalis tuber, 3.5 parts of wind-weeds, 13 parts of common perilla stems, 7 portions of wrinkled giant hyssops, 7 portions of pseudo-ginseng, 13 portions of peppermints, 1 part of spot thatch, 31.01 parts of alginic acids
Sodium, 62.02 parts of glycerine, 93.02 parts of beeswaxs and 13.95 parts of single stearic acid glycerine lipoproteins.
The preparation method of the ointment of body odour is treated, is comprised the following steps：
By Asiatic plantain, lemon peel, the fruit of Chinese wolfberry, cape jasmine, radix glycyrrhizae, litharge, radix scrophulariae, corydalis tuber, the wind-weed, common perilla stem, wrinkled giant hyssop,
Pseudo-ginseng, peppermint, spot thatch add medicine decocting tank after crushing, and add 263.2 parts of water, after stirring, soak 4h；To the medicine decocting tank
394.8 parts of water of middle addition, boil rear slow fire and endure 5h, filter, obtain the first filtrate；Add 263.2 parts into the filter residue being filtrated to get
Water, boil rear slow fire and endure 2h, filter, obtain the second filtrate；First filtrate and second filtrate are merged, concentration, obtained
To the ointment for the treatment of body odour.
Embodiment 6
The ointment for the treatment of body odour includes the raw material of following parts by weight：
8.5 portions of Asiatic plantains, 18 parts of lemon peels, 6 portions of fruits of Chinese wolfberry, 7 portions of cape jasmines, 5 portions of radix glycyrrhizaes, 9 parts of litharges, 3.5 portions of radix scrophulariaes,
8.5 parts of corydalis tubers, 3.2 parts of wind-weeds, 10 parts of common perilla stems, 11 portions of wrinkled giant hyssops, 6.5 portions of pseudo-ginseng, 9 portions of peppermints, 2 parts of spot thatches, 24.13 parts of seas
Mosanom, 72.38 parts of glycerine, 81.43 parts of beeswaxs and 12.06 parts of single stearic acid glycerine lipoproteins.
The preparation method of the ointment of body odour is treated, is comprised the following steps：
By Asiatic plantain, lemon peel, the fruit of Chinese wolfberry, cape jasmine, radix glycyrrhizae, litharge, radix scrophulariae, corydalis tuber, the wind-weed, common perilla stem, wrinkled giant hyssop,
Pseudo-ginseng, peppermint, spot thatch add medicine decocting tank after crushing, and add 321.6 parts of water, after stirring, soak 3h；To the medicine decocting tank
611.04 parts of water of middle addition, boil rear slow fire and endure 5h, filter, obtain the first filtrate；Add 257.28 into the filter residue being filtrated to get
Part water, boils rear slow fire and endures 1h, filters, obtains the second filtrate；First filtrate and second filtrate are merged, concentration,
The ointment for the body odour that obtains medical treatment.
Embodiment 7
The ointment for the treatment of body odour includes the raw material of following parts by weight：
8 portions of Asiatic plantains, 14 parts of lemon peels, 4.5 portions of fruits of Chinese wolfberry, 5.5 portions of cape jasmines, 4 portions of radix glycyrrhizaes, 8.5 parts of litharges, 3 parts it is profound
Ginseng, 8 parts of corydalis tubers, 3 parts of wind-weeds, 12.5 parts of common perilla stems, 10 portions of wrinkled giant hyssops, 6 portions of pseudo-ginseng, 11 portions of peppermints, 1.5 parts of spot thatches, 21.69 parts
Sodium alginate, 72.32 parts of glycerine, 65.08 parts of beeswaxs and 15.91 parts of single stearic acid glycerine lipoproteins.
The preparation method of the ointment of body odour is treated, is comprised the following steps：
By Asiatic plantain, lemon peel, the fruit of Chinese wolfberry, cape jasmine, radix glycyrrhizae, litharge, radix scrophulariae, corydalis tuber, the wind-weed, common perilla stem, wrinkled giant hyssop,
Pseudo-ginseng, peppermint, spot thatch add medicine decocting tank after crushing, and add 248.75 parts of water, after stirring, soak 4h；Boiled medicine to described
497.5 parts of water are added in tank, rear slow fire is boiled and endures 4h, filters, obtains the first filtrate；Add 248.75 into the filter residue being filtrated to get
Part water, boils rear slow fire and endures 1.5h, filters, obtains the second filtrate；First filtrate and second filtrate are merged, be dense
Contracting, the ointment for the body odour that obtains medical treatment.
First, safety testing：
The product mix of Example 1~7, obtains hybrid medicine.
It is dynamic by experiment of the small white mouse of body weight 18-20g male and female half and half using the mixed powder of above-mentioned gained as trial drug
Thing, totally 210, be divided into 7 groups, respectively the medicine of gavage various concentrations, concentration be respectively 10mg/ml, 40mg/ml, 60mg/ml,
80mg/ml, 100mg/ml, administered volume are 40ml/kg, to gastric infusion in mouse one day 3 times, accumulate gastric infusion volume
For 100ml/kg.Observation 7 days, have no overt toxicity reaction and the reaction of pawpaw enteron aisle.Through visually observing after dissection, main organs
Non Apparent Abnormality.
The small white mouse of body weight 18-20g male and female half and half is experimental animal, totally 80, is divided into two groups, carries out long term toxicity examination
Test, one group of administration concentration is 60mg/ml, administered volume 40ml/kg；Another group is isometric distilled water, continuously gavages 3
Individual month, carry out long term toxicity test.Long term toxicity test result shows that the general behavior activity of experimental animal and body weight increase are just
Often, to hematological indices, the organ coefficient of hepatic and renal function and main organs is had no significant effect, and main organs are damaged without obvious pathology
Wound, show medicine nontoxicity.
2nd, the ointment for the treatment body odour for obtaining embodiment 1~7 carries out clinical test, as a result as follows：
1st, subject selects：Select the body odour patient in March, 2012~certain hospital accepts for medical treatment so far totally 400, wherein male
Patient 189, female patient 211.
2nd, packet design：All patients are randomly divided into 8 groups, respectively experimental group 1, experimental group 2, experimental group 3, experimental group 4,
Experimental group 5, experimental group 6, experimental group 7 and control group, each 50, eight groups of patients are at age, the state of an illness etc. without significant difference, tool
There is comparativity.Wherein experimental group 1~7 uses ointment made from embodiment 1~7 respectively.
3rd, instructions of taking：The ointment of experimental group 1~7 is coated at armpit, is smeared uniformly, twice in the morning and evening, is smeared 30 days.
Control group is coated at armpit, smeared uniformly, twice in the morning and evening, smeared 30 days using neat emerging hall Bromhidrosis treating paste.
4th, curative effect judging standard
Cure：Patient's body odour symptom disappears, and body surface recovers normal；
Effectively：Patient's body odour symptom gradually mitigates or symptom disappears；
It is invalid：Body odour symptom is without improvement；
Total effective rate=(curing number of cases+effective number of cases)/case load.
5th, result is as shown in table 1
The treatment results of the experimental group 1~7 of table 1 and control group
A kind of ointment for treating body odour provided by the invention and preparation method thereof is described in detail above, this
Apply specific case in text to be set forth the principle and embodiment of the present invention, the explanation of above example is only intended to
Help to understand method and its core concept of the invention, it is noted that for those skilled in the art,
Without departing from the principles of the invention, some improvement and modification can also be carried out to the present invention, these are improved and modification also falls
Enter in the protection domain of the claims in the present invention.
Claims (7)
1. a kind of plaster for treating body odour, it is characterised in that include the raw material of following parts by weight：
2. ointment as claimed in claim 1, it is characterised in that include the raw material of following parts by weight：
3. ointment as claimed in claim 1 or 2, it is characterised in that also including auxiliary material, the parts by weight of the auxiliary material are 150
~200 parts.
4. ointment as claimed in claim 3, it is characterised in that it is hard that the auxiliary material includes sodium alginate, glycerine, beeswax and list
Resin acid glyceride.
5. a kind of preparation method of the ointment for the treatment of body odour as claimed in claim 1, it is characterised in that comprise the following steps：
By Asiatic plantain, lemon peel, the fruit of Chinese wolfberry, cape jasmine, radix glycyrrhizae, litharge, radix scrophulariae, corydalis tuber, the wind-weed, common perilla stem, wrinkled giant hyssop, three
7th, peppermint, spot thatch add medicine decocting tank after crushing, and add water for the first time, after stirring, soak 3~5h；Into the medicine decocting tank
Second plus water, boil rear slow fire and endure 3~5h, filter, obtain the first filtrate；Add water for the third time into the filter residue being filtrated to get,
Boil rear slow fire and endure 1~2h, filter, obtain the second filtrate；First filtrate and second filtrate are merged, concentration, obtained
To the ointment for the treatment of body odour.
6. preparation method as claimed in claim 5, it is characterised in that also include adding auxiliary material into the material after concentration.
7. preparation method as claimed in claim 5, it is characterised in that the first time add the dosage of water be the Asiatic plantain,
The lemon peel, the fruit of Chinese wolfberry, the cape jasmine, the radix glycyrrhizae, the litharge, the radix scrophulariae, the corydalis tuber, described know
Female, described common perilla stem, the wrinkled giant hyssop, the pseudo-ginseng, the peppermint, 2~3 times of the spot thatch total amount；Described state adds for the second time
The dosage of water is the Asiatic plantain, the lemon peel, the fruit of Chinese wolfberry, the cape jasmine, the radix glycyrrhizae, the litharge, described
Radix scrophulariae, the corydalis tuber, the wind-weed, the common perilla stem, the wrinkled giant hyssop, the pseudo-ginseng, the peppermint, the spot thatch total amount
4~6 times；The dosage for stating third time feedwater is the Asiatic plantain, the lemon peel, the fruit of Chinese wolfberry, the cape jasmine, described
Radix glycyrrhizae, the litharge, the radix scrophulariae, the corydalis tuber, the wind-weed, the common perilla stem, the wrinkled giant hyssop, the pseudo-ginseng, institute
State peppermint, 2~3 times of the spot thatch total amount.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710548286.0A CN107375731A (en) | 2017-07-06 | 2017-07-06 | Treat ointment of body odour and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710548286.0A CN107375731A (en) | 2017-07-06 | 2017-07-06 | Treat ointment of body odour and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107375731A true CN107375731A (en) | 2017-11-24 |
Family
ID=60335629
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710548286.0A Pending CN107375731A (en) | 2017-07-06 | 2017-07-06 | Treat ointment of body odour and preparation method thereof |
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| Country | Link |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105311306A (en) * | 2014-08-02 | 2016-02-10 | 姜丹宁 | Medicine for treating severe body odor |
-
2017
- 2017-07-06 CN CN201710548286.0A patent/CN107375731A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105311306A (en) * | 2014-08-02 | 2016-02-10 | 姜丹宁 | Medicine for treating severe body odor |
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