CN106138740A - A kind of Chinese medicine decoction for treating Qi deficiency blood stasis type cerebral infarction - Google Patents

A kind of Chinese medicine decoction for treating Qi deficiency blood stasis type cerebral infarction Download PDF

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CN106138740A
CN106138740A CN201610760683.XA CN201610760683A CN106138740A CN 106138740 A CN106138740 A CN 106138740A CN 201610760683 A CN201610760683 A CN 201610760683A CN 106138740 A CN106138740 A CN 106138740A
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parts
grams
blood stasis
cerebral infarction
stasis type
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秦月霞
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Abstract

The invention discloses a kind of Chinese medicine decoction for treating Qi deficiency blood stasis type cerebral infarction, it is prepared from by the Chinese crude drug of following weight proportion: Semen Melo 7 parts, Folium Alstoniae Scholaris 6 parts, Indigofera stachyoides Lindl. 5 parts, Rhizoma Chuanxiong 10 parts, breaking cellular wall Pollen Pini 5 parts, 10 parts of white beeswax tree, Fructus Caricae 9 parts, Semen Nigellae 11 parts, gold scorpion 5 parts, beet root 5 parts, month laural cherry 5 parts, Rhizoma Polygonati 5 parts, 6 parts of rolling mountain pearl, Herba Murdanniae Divergentis 5 parts, Radix Salviae Miltiorrhizae 5 parts, 5 parts strictly according to the facts, Wen Shanghai 5 parts, Folium Ilicis Purpureae 5 parts, tragacanth 5 parts, Hirudo 12 parts, dry root of Anacyclus pyrethrum(L.)DC. 5 parts, Rhizoma Acori Graminei 5 parts, ove Notarchi 5 parts, blue 5 parts of two tip of a leaf lips, Samantabhadra dish 5 parts.Clinical trial certificate, the present invention reasonable compatibility by Chinese crude drug, contribute to treating Qi deficiency blood stasis type cerebral infarction, and can effectively reduce complication, reach integrally-regulated and long-term effect good effects.

Description

A kind of Chinese medicine decoction for treating Qi deficiency blood stasis type cerebral infarction
Technical field
The present invention relates to a kind of Chinese medicine decoction, be specifically related to a kind of Chinese medicine for treating Qi deficiency blood stasis type cerebral infarction Decoction.
Background technology
Cerebral infarction means because of cerebral tissue blood supply obstacle, the focal brain tissue ischemia that ischemia, anoxia cause Necrosis or softening, have sickness rate height, case fatality rate height, disability rate high, be the frequently-occurring disease in cerebrovascular disease.Deficiency of vital energy blood Stasis of blood type cerebral infarction symptom mostly is hemiplegia, crooked mouth and tongue, and speech is not smoothgoing puckery or in silence, feels to go down or disappear, pale complexion, Shortness of breath and fatigue, from sweating, dimly pale tongue, white and greasy fur or have indentation, deep-thready pulse.Conventional each doctor reducing phlegm merely, to invigorate blood circulation or Qi-restoratives Therapeutic Principle, only relies on several taste medicine and is difficult to look after comprehensively, and unsatisfactory curative effect, so must suitably be coordinated by multi-medicament, carries High curative effect or minimizing untoward reaction, to adapt to the treatment of the complicated state of an illness.In view of various Chinese crude drugs various active composition in vivo Interaction sufficiently complex, between the change of the aspects such as various medicines pharmacokinetics in vivo and pharmacodynamics can be to medicine Interaction produce various impacts, during drug combination, both may produce Synergistic drug effect, it is also possible to produce antagonism make With, and then causing Drug therapy declines or Endodontic failure, some drug combination also can make drug toxicity strengthen, and causes not Good reaction；Even if drug combination makes effect strengthen, but can exceed the tolerant energy of body when therapeutical effect excessively strengthens Power, it is possible to cause untoward reaction, or even harm patient.Part research is toward from intending Chinese medicinal formulae to treatment Qi deficiency blood stasis type ischemia Property apoplexy, the most easily problem appear to is that the compatibility of medicines in a prescription is unreasonable, may often be such that only from some single or polypharmaceutic indivedual merit Can cure mainly and remove to copy mechanically and apply indiscriminately Chinese medical theory with some pharmacodynamic index, prescription flavour of a drug are arbitrarily added and subtracted, and cause prescription unreasonable, with Chinese medical theory contradicts.
Summary of the invention
It is desirable to provide a kind of Chinese medicine decoction for treating Qi deficiency blood stasis type cerebral infarction, by Chinese crude drug Reasonable compatibility, contributes to treating Qi deficiency blood stasis type cerebral infarction, and can effectively reduce complication, reach integrally-regulated and at a specified future date The good effects of effect.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine decoction for treating Qi deficiency blood stasis type cerebral infarction, by the Chinese crude drug preparation of following weight proportion Become: Semen Melo 7 parts, Folium Alstoniae Scholaris 6 parts, Indigofera stachyoides Lindl. 5 parts, Rhizoma Chuanxiong 10 parts, breaking cellular wall Pollen Pini 5 parts, 10 parts of white beeswax tree, Fructus Caricae 9 parts, Semen Nigellae 11 parts, gold scorpion 5 parts, beet root 5 part, month laural cherry 5 parts, Rhizoma Polygonati 5 parts, 6 parts of rolling mountain pearl, Herba Murdanniae Divergentis 5 parts, red Join 5 parts, 5 parts strictly according to the facts, Wen Shanghai 5 parts, Folium Ilicis Purpureae 5 parts, tragacanth 5 parts, Hirudo 12 parts, dry root of Anacyclus pyrethrum(L.)DC. 5 parts, Rhizoma Acori Graminei 5 Part, ove Notarchi 5 parts, two tip of a leaf lips blue 5 parts, Samantabhadra dish 5 parts.
Preparation method is: above-mentioned pulverizing medicinal materials in addition to breaking cellular wall Pollen Pini is become coarse powder；Decoct twice, decoct for the first time Add water 8 times amount, soaks 2h, decocts 3h, filters；Second time decocts 6 times amount that add water, and decocts 2h, filters；Merge twice decocting liquid again Subpackage after mixing homogeneously with breaking cellular wall Pollen Pini.
Further, above-mentioned Chinese medicine decoction use in preparation treatment or prevention Qi deficiency blood stasis type cerebral infarction medicine On the way.
The pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
Semen Melo [source] is the dry mature seed of cucurbitaceous plant Fructus Melo.[nature and flavor] one-level heat two grades is wet, sweet in the mouth.[function Cure mainly] raw humidogene heat, to clear up kidney, bladder, intestinal, diuresis and expelling stone, open liver resistance, relieving cough and resolving phlegm, kidney tonifying, essence replenishing, speckle dispelling is raw Brightness.Curing mainly in cold or black gallbladder matter disease, such as urinary system calculus, urine retention constipation, liver inflammation swells, and parched throat larynx is done, and cough is glutinous Expectorant, oligospermia of suffering from a deficiency of the kidney, various black speck etc..
The dry leaves of Folium Alstoniae Scholaris [source] Apocynaceae Alstonia plant sugar gum.[nature and flavor] bitter in the mouth, micro-puckery, Cold.[function cures mainly] Qinghuo Jiedu, reducing swelling and alleviating pain, relieving cough and resolving phlegm.
Indigofera stachyoides Lindl. [source] pulse family Indigofera stachyoides Lindl., is used as medicine with root.[nature and flavor] micro-hardship, puckery, temperature.[function cures mainly] only invigorates blood circulation Bitterly, relaxing muscles and tendons and activating QI and blood in the collateral, enriching yin and nourishing kidney, hemostasis by invigorating QI.Cure mainly metrorrhagia, traumatic injury and rheumatism, liver cirrhosis, infantile malnutrition, dysentery；Ulcer with the passing of time QI and blood Two is empty.
The dry rhizome of Rhizoma Chuanxiong [source] samphire Rhizoma Chuanxiong.[nature and flavor] are pungent, temperature.[return through] returns liver, gallbladder, pericardium channel. [function cures mainly] blood-activating and qi-promoting, wind-expelling pain-stopping.
Breaking cellular wall Pollen Pini [source] medical material Ji Yuan: Pollen Pini is the spermatid of pinaster pistil, has another name called pine yellow, is to pick up from me Pure, the dry pollen of state indigenous tree pinaceae plant Pinus massoniana Lamb.[function cures mainly] is containing the whole activity battalion needed for life entity Forming part, including multiple proteins, aminoacid, mineral, enzyme and coenzyme, nucleic acid, monosaccharide, polysaccharide etc., total content reaches 200 Remaining kind.Additionally possibly together with nearly hundred kinds of enzymes, biotin, nucleic acid, cellulose, unsaturated fatty acid, Flavonoid substances, reeds in Pollen Pini Fourth isoreactivity material.
White beeswax tree [source] is the dry seed that Oleaceae plants point leaf Chinese ash etc. belongs to various plants together.[nature and flavor] two Level is xeothermic.[function cures mainly] raw dry heat, essence replenishing and yang invigorating, tonifying the kidney to consolidate the essence, to mend god and feel at ease, relieving cough and asthma, urination-promoting calculus-eliminating, cold relieving helps Pregnant.
Fructus Caricae [source] is fruit and root, the leaf of Caricaceae plant Fructus Caricae.[nature and flavor] taste is sweet, micro-puckery, cool in nature.Enter Water, wind, Tu Ta.[effect] stomach invigorating, venting QI-blood, relieve the pain pain.Cure mainly abdominal distention, anorexia, headache and dizziness, intractable Headache, arthralgia due to wind-cold-dampness disease, limbs joint aches, joint stuffiness.
Semen Nigellae [source] is the dry mature seed of ranunculaceae plant Semen Nigellae.[nature and flavor] sweet in the mouth, pungent, property Temperature.[function cures mainly] conditioning stomach-fire, aid digestion, teeth consolidating.Curing mainly dyspepsia, hepatalgia, liver function fails.
Gold scorpion [source] is the dry entirety of Buthidae animal East Asia mistake scorpion.[nature and flavor] sweet in the mouth, pungent, salty, property is put down.Poisonous. [effect] improving eyesight, town is conspicuous to be depended on, more the lung-pulse, cephalocathartic.Cure mainly visual deterioration, epilepsy.
Beet root [source] is the root of euphorbia plant Gekko Swinhonis wood.[nature and flavor] taste is sweet, cool in nature.Enter water, Tu Ta.[function master Control] Qinghuo Jiedu, reducing swelling and alleviating pain.Cure mainly laryngopharynx swelling and pain, laryngopharynx swelling and pain, cough a lot of phlegm, spitting of blood, scabies.
Moon laural cherry [source] is the fruit of barrier section plant Laurel.[nature and flavor] two grades are xeothermic, acrid in the mouth.[effect] cold removing Antiinflammatory, strengthens audition, calculus dissolving and excreting, removing toxic substances etc.；Control cold inflammation to swell, auditory dysesthesia, various calculus, various poisonings etc..Cure mainly wet Cold or lymphatic temperament disease, such as cold arthralgia, Minor articulus pain, sciatica, cough, asthma, urine retention, the enuresis, warp Close, moist paralysis, facial paralysis, tremor and white macula, freckle etc..
The dry rhizome of Rhizoma Polygonati [source] liliaceous plant P. kingianum.[nature and flavor] are sweet, flat.[return through] returns spleen, lung, kidney Warp.[function cures mainly] boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, the deficiency of the lung is dry Coughing, asthenia of essence and blood, interior-heat is quenched one's thirst.
Rolling mountain pearl [source] is the entirety of Glomeridae animal glomeris nipponica Kishida.[nature and flavor] acrid in the mouth, property heat.[function cures mainly] Dispelling wind and removing obstruction in the collateral, eliminating stasis to stop pain.Cure mainly rheumatic arthralgia, muscle arteries and veins contracture, traumatic injury.Fracture swells and ache.
Herba Murdanniae Divergentis [source] medical material Ji Yuan: for root or the Herb of Commelianaceae plant purple back of the body Herba Pyrolae.[nature and flavor] are sweet；Micro- Bitter；Flat.[function cures mainly] clearing away lung-heat to relieve cough；Invigorating the lung and the kidney；Regulating menstruation, hemostasis.Main cough due to lung-heat；The deficiency of vital energy is breathed with cough；Dizziness and tinnitus；Fracture； Spit blood.[pharmacology] its can effectively suppress the lipid peroxidation that chemical toxicant induces, therefore can treat in food, toadstool, medicine Poison.
Radix Salviae Miltiorrhizae [source] this product is the dry root and rhizome of labiate Radix Salviae Miltiorrhizae.[nature and flavor] are bitter, are slightly cold.[return through] GUIXIN, Liver Channel.[function cures mainly] stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen amasss Poly-, chest and abdomen twinge, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia；Hepatosplenomegaly, angina pectoris.
The 3 kinds of plants [originated] strictly according to the facts Anacardiaceae two genus (i.e. Anacardium and meat torr fruit belongs to): chicken Fructus anacardii, big mesophyll torr Really, the fruit of chicken loin torr fruit.[nature and flavor] are xeothermic.[function cures mainly] strong muscle is good for flesh, hard masses softening and resolving, dampness reducing urination, and red skin is raw to be created, Hypermnesis, cold relieving tonifying YANG.Cure mainly raw property and cat liquid matter disease, cutaneous horn too much property disease, such as paralysis, facial paralysis, tremble Disease, body, without feeling disease, knots, flat defect, incontinence of urine, skin speckle, white paralysis wind, hypomnesis, neurasthenia, tooth pine Move.
Wen Shanghai [source] is bulb or the herb of orchid Herba Murdanniae Divergentis.[nature and flavor] bitter in the mouth, micro-fiber crops, cool in nature.Enter four towers. [function cures mainly] is adjusted and is filled blood, Qinghuo Jiedu, dampness removing jaundice eliminating.Cure mainly asthenia of qi and blood in puerperal, headache and dizziness, unable, weak and sickly, food Thing is poisoned, vomiting and dirarrhea, and Light-headedness is fainted suddenly, tic of the limbs, spits out white foams, syncope, headache and dizziness, jaundice.
Folium Ilicis Purpureae [source] is the blade of holly plant Ilicis Purpureae.[chemical analysis] leaf contains two kinds of antipathogenic compositions, wherein One of be protocatechuic acid, separately containing volatile oil, flavonoid.[nature and flavor] are pained, cold.[function cures mainly] controls scald, and ulcer does not heals Close, thromboangiitis obliterans, acute and chronic bronchitis, pneumonia, urinary tract infection, bacillary dysentery, traumatic hemorrhage, freeze chilblain, chap.
Tragacanth [source] is leguminous plant Calculus Bovis from Northwest of China stilbene and belongs to him together and plant the glue fat of plant.[nature and flavor] are flat, the wettest, taste Light.[function cures mainly] corrects the evil of hundred tastes, raw moistening lung, cough-relieving, hemostasis, sore throat relieving profit larynx, tonneau urine, and antiinflammatory is healed skin ulcer.Cure mainly Dryness contains caused various diseases partially, and such as dryness of the lung dry cough, dry laryngopharynx, hoarseness, intestinal ulcer, urethra skin infection, urine is burnt Heat.
Hirudo [source] this product is Hirudinidae animal whitmania, Hirudo or the dry body of Folium Salicis Babylonicae Hirudo.[nature and flavor] are salty, bitter, flat； Slightly poisonous.[return through] returns Liver Channel.[function cures mainly] removing blood stasis, removing blood stasis, stimulates the menstrual flow.For lump in the abdomen mass in the abdomen, blood stasis amenorrhea, injury from falling down.
Dry root of Anacyclus pyrethrum(L.)DC. [source] is the root of feverfew Rome Pyrethrum.Peppery and the numb tongue of [nature and flavor] acrid in the mouth.[function cures mainly] The strong muscle of cold relieving, opens retardance, removes excess in brain, warm-up tonifying YANG, and tonneau is through water, controlling nocturnal emission with astringent drugs, wind-expelling pain-stopping, drying dampness to eliminate phlegm, nourishing Neural.Curing mainly raw property or open-minded liquid matter disease, such as paralysis, facial paralysis, of flaccid muscles, paralysis, vibration, skin ulcer is sick, and tongue weight, libido subtracts Moving back, seminal fluid is not solid, and amenorrhea is not smooth, headache toothache, and excessive phlegm is coughed, neurasthenia.
The rhizome of Rhizoma Acori Graminei [source] acorus gramineus araceae plant.[function cures mainly] removing dampness is whetted the appetite, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.The most hungry for gastral cavity painful abdominal mass, a mouthful dysentery of keeping silent, coma epilepsy, forgetful deafness.Regulate the flow of vital energy, invigorate blood circulation, dissipate wind, dry.Control epilepsy, syncope due to accumulation of phlegm, Calentura coma, forgetful, deafness with qi stagnation, ambition is unhappy, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury.
Ove Notarchi [source] medical material Ji Yuan: the ovum group for sea hare section animal Notarchus leachii cirrosus carries.[nature and flavor] sweet in the mouth；Salty； Cold in nature.[return through] returns lung；Kidney channel.[function cures mainly] clearing away heat and nourishing YIN；Softening the hard mass expectorant.The main dryness of the lung is breathed with cough；Epistaxis, goiter；Scrofula.
Blue [source] the orchid family Herba Platantherae Japonicae platymiscium two tip of a leaf lip of two tip of a leaf lips is blue, is used as medicine with tuber.[nature and flavor] are bitter, flat. [function cures mainly] tonifying the lung granulation promoting, removing stasis to stop bleeding.For pulmonary tuberculosis hemoptysis, haematemesis, epistaxis；Wound, carbuncle, burn due to hot liquid or fire are controlled in external.
The Samantabhadra dish of Samantabhadra dish [source] Cruciferae, with all herbal medicine.[nature and flavor] are sweet, flat.[function cures mainly] subsides a swelling, and mends Empty.Cure mainly asthenia internal injury, dizzy, fatigue and asthenia, red collapses, the disease such as leucorrhea.
Herba Polygoni Capitati [source] is the herb of polygonaceae plant Herba Polygoni Capitati.[nature and flavor] bitter in the mouth, pungent, property is cold.[function cures mainly] heat clearing away Removing toxic substances, inducing diuresis for treating stranguria syndrome, promoting blood circulation and stopping pain;Curing mainly wing moon bright scorching, dysentery, nephropyelitis, rheumatalgia, lithangiuria, tumbling down damages, skin infection Eczema, impetigo, stranguria caused by urinary stone.Edema.
Herba Veronicastri Sibirici [source] is root or the herb of ranunculaceae plant Radix Anemones Rivularis.[nature and flavor] bitter in the mouth, micro-pungent, slightly cool in nature;Have little Poison.[function cures mainly] heat-clearing and toxic substances removing, relaxing muscles and tendons to promote blood circulation, detumescence, pain relieving.Cure mainly laryngopharynx swelling and pain, ache the cheek, tuberculosis, carbuncle subcutaneous ulcer toxic swelling, malaria Disease, cough with copious phlegm, lymphadenitis, jaundice due to damp-heat, rheumatalgia, stomachache, toothache, tumbling down damage etc..
Sheep milk [source] is the band rhizome herb of Bignoniaceae plant Herba Melicae Scabrosae.[nature and flavor] bitter in the mouth, micro-pungent, property is cold.[function Cure mainly] invigorating spleen to remove dampness, promoting flow of QI and blood.Cure mainly and have loose bowels, dysentery, stomachache, hypochondriac pain, rheumatalgia.Menoxenia.Carbuncle, fracture.
Coloquintida [source] is the dry mature fruit of cucurbitaceous plant coloquintida.[nature and flavor] two grades are xeothermic, and acrid in the mouth is strong. [function cures mainly] is raw dry raw cold, removes abnormal lymphatic temperament, opens brain resistance, dissipate gas pain relieving, attack and rush down dampness, eliminate jaundice.Cure mainly wet Cold or lymphatic temperament disease, cold head disease, such as headache, migraine, feeling of fullness in the head, paralysis, epilepsy, toothache, otalgia, forgetful, Dizzy, it is that diligent happy venom flees to block in organs such as brain, stomach, intestinal in eye etc. and unnecessary pathogenic body fluid, various edema, habitual Constipation, jaundice.
The dry mature seed of Ou Zhen [source] Betulaceae Ou Zhen.[nature and flavor] one-level is xeothermic, sweet in the mouth.[function cures mainly] Raw dry heat, dampness supplementing the brain, hypermnesis, controlling nocturnal emission with astringent drugs replenishing essence, stomach warming tonifying YANG, the strong muscle of warming the meridian, relieving cough and asthma.Cure mainly raw property or kill Liquid matter, as moist brain is empty, forgetful, premature ejaculation, seminal emission, cold seminal fluid reduces, and sun expectorant of suffering from a deficiency of the kidney, muscles and bones is weak, cough and asthma.
Gold leaf tree [source] black apple University of Science and Technology band, is used as medicine with root, leaf.[meridian distribution of property and flavor] is sweet, puckery, temperature.[function cures mainly] Blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain.Cure mainly traumatic injury congestive edema, rheumatic arthritis, fracture-dislocation.
Ovum Gallus domesticus Flavus [source] is the egg yolk of Phasianidae animal man chicken.[nature and flavor] sweet in the mouth；Property flat.[return through] heart；Kidney；Spleen channel. [function cures mainly] is nourshing Yin and drynsessmoistening prescription；Nourishing blood to stop wind syndrome.Main vexed insomnia；Calentura convulsion is fainted；Viscerasthenia hemoptysis；Vomiting；Dysentery；Scald；Heat Skin ulcer；Hepatitis；Infantile dyspepsia.
The present invention compared with prior art, has the advantages that
1, the selected medicament composing prescription of the present invention, its drug component through dialectical compatibility, complements each other using, has synergism, Playing effect of kidney and spleen invigorating, benefiting QI for activating blood circulation, strengthening the body resistance altogether, the treatment to Qi deficiency blood stasis type cerebral infarction reaches specimen together Control.Prescription is particular about monarch, four natures and five flavors of drug lifting, and white beeswax tree, dry root of Anacyclus pyrethrum(L.)DC., Radix Salviae Miltiorrhizae, Rhizoma Polygonati etc. are monarch drug altogether, Compound recipe plays a leading role, treats disease by acting on major target class；Ove Notarchi, Rhizoma Acori Graminei, rolling mountain pearl, Folium Alstoniae Scholaris etc. are minister Medicine, strengthens the pharmacological action of monarch drug, thus reduces monarch drug required dosage by acting on the target spot identical with monarch drug；Rhizoma Chuanxiong, Hirudos etc. make for assistant altogether, to improve the bioavailability of monarch, ministerial drug, coordinate the activity of their each composition.Wherein, strictly according to the facts, in vain Wax tree, Rhizoma Polygonati, Radix Salviae Miltiorrhizae, Semen Nigellae are the most collaborative, take into account QI and blood warming and recuperating the kidney-YANG on the basis of the kidney invigorating, and Hirudo Hechuan rhizome of chuanxiong draws Medicine is up with except the stasis of blood of brain network, and Folium Ilicis Purpureae, Samantabhadra dish regulation coagulation function, reduction blood fat, free radical resisting damage are, and then improve god Through function, significantly improve clinical efficacy.Due to multiple location infarct, be admitted to hospital to morbidity manifesting of 14 days phlegm syndrome be cerebral infarction The risk factor of recurrence, therefore Semen Melo, dry root of Anacyclus pyrethrum(L.)DC., two tip of a leaf lip orchid threes are specially shared turbid to reduce phlegm by the present invention, subtract Light neurologic defect, thus effectively prevent recurrence, promote patient treatment effective percentage.Additionally, the ove Notarchi that is especially added with of the present invention and lamp After platform leaf compatibility, acting on the different target spots of body, synergism can produce the special effect improving human immunologic function, can have The effect regulation each function of body, improves body and resists the ability of external toxin puzzlement, the generation of complication prevention.Samantabhadra dish, Indigofera stachyoides Lindl., Fructus Caricae phase 5, the shortness of breath and fatigue symptom that notable alleviation Qi deficiency blood stasis type cerebral infarction is common.
2, the present invention is directed to Qi deficiency blood stasis type cerebral infarction pathogeny, launch to control from Mutiple Targets, too many levels, multipath Treat, have in clinical practice rapid-action, determined curative effect, patient compliance are good, safe without toxic side effect, can significantly improve patient Autoimmunity, treating both the principal and secondary aspects of a disease prevents recurrence, thus has wide potential applicability in clinical practice.
Detailed description of the invention
In order to be more fully understood that and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Weigh: Semen Melo 7 grams, Folium Alstoniae Scholaris 6 grams, Indigofera stachyoides Lindl. 5 grams, Rhizoma Chuanxiong 10 grams, breaking cellular wall Pollen Pini 5 grams, 10 grams of white beeswax tree, Fructus Caricae 9 grams, Semen Nigellae 11 grams, gold scorpion 5 grams, beet root 5 gram, month laural cherry 5 grams, Rhizoma Polygonati 5 grams, 6 grams of rolling mountain pearl, Herba Murdanniae Divergentis 5 grams, Radix Salviae Miltiorrhizae 5 grams, strictly according to the facts 5 grams, Wen Shanghai 5 grams, Folium Ilicis Purpureae 5 grams, tragacanth 5 grams, Hirudo 12 grams, dry root of Anacyclus pyrethrum(L.)DC. 5 grams, stone Rhizoma Acori Graminei 5 grams, ove Notarchi 5 grams, two tip of a leaf lips blue 5 grams, Samantabhadra dish 5 grams.
Preparation method is: above-mentioned pulverizing medicinal materials in addition to breaking cellular wall Pollen Pini is become coarse powder；Decoct twice, decoct for the first time Add water 8 times amount, soaks 2h, decocts 3h, filters；Second time decocts 6 times amount that add water, and decocts 2h, filters；Merge twice decocting liquid again Subpackage after mixing homogeneously with breaking cellular wall Pollen Pini.
Usage and dosage: oral, every day 2 times, the most each 1 time, each 100ml；Within 30 days, it is 1 course for the treatment of, takes 1 treatment continuously Journey.
Clinical data:
1, case selection:
In the Qi deficiency blood stasis type Ischemic Apoplexy Patients 40 example clinical observation of my institute's diagnosis and treatment since selecting 2013, clinical symptoms is equal Meet Qi deficiency blood stasis type cerebral infarction diagnosis and treatment standard.Patient is randomly divided into treatment group and matched group two groups, and treatment group 20 example is right According to organizing 20 examples.Treatment group and the course of disease of two groups of cases of matched group, degrees of symptoms are basically identical, and without significant difference, having can Compare property.
2, medicament selection:
Treatment group takes the Chinese medicine decoction obtained by the embodiment of the present invention 1, oral, every day 2 times, the most each 1 time, each 100ml； Within 30 days, it is 1 course for the treatment of, takes 1 course for the treatment of continuously.
Matched group gives western medicine routine treatment, and including anticoagulant, thrombolytic, to improve cerebral circulation, expansion of cerebral vascular and calcium ion short of money Anti-agents etc., the course for the treatment of is with treatment group.
1 course for the treatment of is treated in smelting continuously, contrasts two groups of curative effects.
3, efficacy determination:
(1) substantially curing: main physical signs and transference cure or significantly alleviate, function is recovered completely or substantially recovers, and takes care of oneself Person.
(2) take a turn for the better: main physical signs and symptom have alleviated, and function makes moderate progress.But the person of can't take care of oneself.
(3) do not heal: before and after treatment, main physical signs and symptom are without improving, and even increase the weight of.
4, result:
Selecting in the treatment group of the embodiment of the present invention 1 Chinese medicine decoction, basic healing 15 examples, take a turn for the better 6 examples, the most 1 example, untoward reaction 0 example, basic cure rate 75%, total effective rate 100%.Follow up a case by regular visits to 24 months curing patient's tracking, without 1 example recurrence.
Basic healing 9 examples in matched group, take a turn for the better 6 examples, the most 5 examples, untoward reaction 0 example, basic cure rate 45%, the most effectively Rate 75%.Follow up a case by regular visits to 24 months curing patient's tracking, without 1 example recurrence.
Result above shows, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Embodiment 2
Weigh: Semen Melo 7 grams, Folium Alstoniae Scholaris 6 grams, Indigofera stachyoides Lindl. 5 grams, Rhizoma Chuanxiong 10 grams, breaking cellular wall Pollen Pini 5 grams, Semen Nigellae 11 grams, Gold scorpion 5 grams, beet root 5 gram, month laural cherry 5 grams, Rhizoma Polygonati 5 grams, 6 grams of rolling mountain pearl, Herba Murdanniae Divergentis 5 grams, Radix Salviae Miltiorrhizae 5 grams, strictly according to the facts 5 grams, Wen Shanghai 5 grams, Folium Ilicis Purpureae 5 grams, tragacanth 5 grams, Hirudo 12 grams, dry root of Anacyclus pyrethrum(L.)DC. 5 grams, Rhizoma Acori Graminei 5 grams, ove Notarchi 5 grams, two tips of a leaf Lip blue 5 grams, Samantabhadra dish 5 grams.Preparation method is with embodiment 1.
10 Qi deficiency blood stasis type Ischemic Apoplexy Patients of the Chinese medicine decoction that the selection embodiment of the present invention 2 is made are controlled substantially More 7 examples, take a turn for the better 2 examples, the most 1 example, untoward reaction 0 example, basic cure rate 70%, total effective rate 90%.To cure patient follow the tracks of with Visit 24 months, without 1 example recurrence.
Embodiment 3
Weigh: Folium Alstoniae Scholaris 6 grams, Indigofera stachyoides Lindl. 5 grams, Rhizoma Chuanxiong 10 grams, breaking cellular wall Pollen Pini 5 grams, 10 grams of white beeswax tree, Fructus Caricae 9 grams, Semen Nigellae 11 grams, gold scorpion 5 grams, beet root 5 gram, month laural cherry 5 grams, Rhizoma Polygonati 5 grams, 6 grams of rolling mountain pearl, Herba Murdanniae Divergentis 5 grams, Radix Salviae Miltiorrhizae 5 Gram, 5 grams strictly according to the facts, Wen Shanghai 5 grams, Folium Ilicis Purpureae 5 grams, tragacanth 5 grams, Hirudo 12 grams, Rhizoma Acori Graminei 5 grams, ove Notarchi 5 grams, Samantabhadra Dish 5 grams.Preparation method is with embodiment 1.
In 10 Qi deficiency blood stasis type Ischemic Apoplexy Patients of the Chinese medicine decoction that the selection embodiment of the present invention 3 is made, substantially Curing 6 examples, take a turn for the better 2 examples, the most 2 examples, untoward reaction 0 example, basic cure rate 60%, total effective rate 80%.Follow the tracks of curing patient Follow up a case by regular visits to 24 months, 2 example recurrences.
Embodiment 4
Weigh: Semen Melo 7 grams, Folium Alstoniae Scholaris 6 grams, Indigofera stachyoides Lindl. 5 grams, Rhizoma Chuanxiong 10 grams, breaking cellular wall Pollen Pini 5 grams, 10 grams of white beeswax tree, Sheep milk 9 grams, Semen Nigellae 11 grams, Herba Veronicastri Sibirici 5 grams, beet root 5 gram, month laural cherry 5 grams, Rhizoma Polygonati 5 grams, 6 grams of rolling mountain pearl, Folium Bambusae Blue 5 grams, Radix Salviae Miltiorrhizae 5 grams, strictly according to the facts 5 grams, Herba Polygoni Capitati 5 grams, Folium Ilicis Purpureae 5 grams, tragacanth 5 grams, Hirudo 12 grams, dry root of Anacyclus pyrethrum(L.)DC. 5 grams, Rhizoma Acori Graminei 5 grams, ove Notarchi 5 grams, two tip of a leaf lips blue 5 grams, Samantabhadra dish 5 grams.Preparation method is with embodiment 1.
Embodiment 5
Weigh: 7 grams of gold leaf tree, Semen Melo 7 grams, Folium Alstoniae Scholaris 6 grams, Indigofera stachyoides Lindl. 5 grams, Rhizoma Chuanxiong 10 grams, breaking cellular wall Pollen Pini 5 grams, white Wax tree 10 grams, Fructus Caricae 9 grams, Semen Nigellae 11 grams, gold scorpion 5 grams, beet root 5 grams, Rhizoma Polygonati 5 grams, 6 grams of rolling mountain pearl, Herba Murdanniae Divergentis 5 Gram, Radix Salviae Miltiorrhizae 5 grams, strictly according to the facts 5 grams, Wen Shanghai 5 grams, Folium Ilicis Purpureae 5 grams, tragacanth 5 grams, Hirudo 12 grams, dry root of Anacyclus pyrethrum(L.)DC. 5 grams, stone Rhizoma Acori Graminei 5 grams, ove Notarchi 5 grams, two tip of a leaf lips blue 5 grams, Ovum Gallus domesticus Flavus 5 grams.Preparation method is with embodiment 1.
Embodiment 6
Weigh: coloquintida 7 grams, Semen Melo 7 grams, Folium Alstoniae Scholaris 6 grams, Indigofera stachyoides Lindl. 5 grams, Rhizoma Chuanxiong 10 grams, breaking cellular wall Pollen Pini 5 grams, white Wax tree 10 grams, Fructus Caricae 9 grams, Semen Nigellae 11 grams, gold scorpion 5 grams, beet root 5 grams, Rhizoma Polygonati 5 grams, 6 grams of rolling mountain pearl, Herba Murdanniae Divergentis 5 Gram, Radix Salviae Miltiorrhizae 5 grams, strictly according to the facts 5 grams, Samantabhadra dish 5 grams, Folium Ilicis Purpureae 5 grams, tragacanth 5 grams, Hirudo 12 grams, dry root of Anacyclus pyrethrum(L.)DC. 5 grams, stone Rhizoma Acori Graminei 5 grams, ove Notarchi 5 grams, two tip of a leaf lips blue 5 grams, Ovum Gallus domesticus Flavus 5 grams.Preparation method is with embodiment 1.
Embodiment 7
Weigh: Semen Melo 7 grams, Folium Alstoniae Scholaris 6 grams, Indigofera stachyoides Lindl. 5 grams, Rhizoma Chuanxiong 10 grams, Ou Zhen 5 grams, 10 grams of white beeswax tree, Fructus Caricae 9 grams, Semen Nigellae 11 grams, gold scorpion 5 grams, beet root 5 grams, 5 grams of gold leaf tree, Rhizoma Polygonati 5 grams, roll 6 grams of mountain pearl, Herba Murdanniae Divergentis 5 grams, Radix Salviae Miltiorrhizae 5 grams, strictly according to the facts 5 grams, Wen Shanghai 5 grams, Folium Ilicis Purpureae 5 grams, tragacanth 5 grams, Hirudo 12 grams, dry root of Anacyclus pyrethrum(L.)DC. 5 grams, Rhizoma Acori Graminei 5 grams, Ove Notarchi 5 grams, two tip of a leaf lips blue 5 grams, Samantabhadra dish 5 grams.Preparation method is with embodiment 1.
Embodiment 8
Weigh: 7 grams of gold leaf tree, Semen Melo 7 grams, Folium Alstoniae Scholaris 6 grams, Indigofera stachyoides Lindl. 5 grams, Rhizoma Chuanxiong 10 grams, Herba Polygoni Capitati 5 grams, Chinese ash Son 10 grams, Fructus Caricae 9 grams, Semen Nigellae 11 grams, gold scorpion 5 grams, beet root 5 grams, Rhizoma Polygonati 5 grams, 6 grams of rolling mountain pearl, Herba Murdanniae Divergentis 5 grams, Little Qin imperatoria 5 grams, strictly according to the facts 5 grams, coloquintida 5 grams, Folium Ilicis Purpureae 5 grams, tragacanth 5 grams, Hirudo 12 grams, dry root of Anacyclus pyrethrum(L.)DC. 5 grams, stone Rhizoma Acori Graminei 5 grams, Ou Zhen 5 grams, two tip of a leaf lips blue 5 grams, Ovum Gallus domesticus Flavus 5 grams.Preparation method is with embodiment 1.
Select the Chinese medicine decoction that embodiment of the present invention 4-8 is made, give 1 Qi deficiency blood stasis type Ischemic Apoplexy Patients clothes respectively With, oral, oral, every day 2 times, the most each 1 time, each 100ml, the most successfully cures.Wherein: take during embodiment 4 makes The patient of medicine decoction, the situation that after taking continuously 28 days, numb limbs and tense tendons is unable is improved the most obvious；Take during embodiment 5 makes The patient of medicine decoction, after taking continuously 22 days, limbs pain and numbness disappears；Take the patient of the Chinese medicine decoction that embodiment 6 is made, The situation that after taking continuously 20 days, numb limbs and tense tendons is unable is improved the most obvious；Take the patient of the Chinese medicine decoction that embodiment 7 is made, After taking continuously 18 days, limbs pain and numbness disappears；Take the patient of the Chinese medicine decoction that embodiment 8 is made, after taking 15 days continuously The unable situation of numb limbs and tense tendons is improved more obvious, can do simple housework, leave hospital after the 25th day.
Obviously, the above embodiment of the present invention is only for clearly demonstrating example of the present invention, and is not right The restriction of embodiments of the present invention, the such as present invention, in addition to making decoction agent, can also be used with common technology and make other oral agents Type.Relevant Chinese medicine and pharmacology thereof all can be obtained by existing open source literature and network, it is also possible to the medical material of close effect instead of Alternative.For those of ordinary skill in the field, other multi-form can also be made on the basis of the above description Change or variation.Here cannot all of embodiment be given exhaustive.Every technical scheme that belongs to is extended Go out obviously changes or changes the row still in protection scope of the present invention.

Claims (3)

1. the Chinese medicine decoction being used for treating Qi deficiency blood stasis type cerebral infarction, it is characterised in that by following weight proportion Chinese crude drug is prepared from: Semen Melo 7 parts, Folium Alstoniae Scholaris 6 parts, Indigofera stachyoides Lindl. 5 parts, Rhizoma Chuanxiong 10 parts, breaking cellular wall Pollen Pini 5 parts, Chinese ash Son 10 parts, Fructus Caricae 9 parts, Semen Nigellae 11 parts, gold scorpion 5 parts, beet root 5 part, month laural cherry 5 parts, Rhizoma Polygonati 5 parts, rolling mountain pearl 6 Part, Herba Murdanniae Divergentis 5 parts, Radix Salviae Miltiorrhizae 5 parts, strictly according to the facts 5 parts, Wen Shanghai 5 parts, Folium Ilicis Purpureae 5 parts, tragacanth 5 parts, Hirudo 12 parts, arna Its root 5 parts, Rhizoma Acori Graminei 5 parts, ove Notarchi 5 parts, two tip of a leaf lips blue 5 parts, Samantabhadra dish 5 parts.
The preparation side of a kind of Chinese medicine decoction for treating Qi deficiency blood stasis type cerebral infarction the most according to claim 1 Method, it is characterised in that above-mentioned pulverizing medicinal materials in addition to breaking cellular wall Pollen Pini is become coarse powder；Decoct twice, decoct for the first time and add water 8 Times amount, soaks 2h, decocts 3h, filters；Second time decocts 6 times amount that add water, and decocts 2h, filters；Merge twice decocting liquid again with breaking cellular wall Subpackage after Pollen Pini mix homogeneously.
Chinese medicine decoction the most according to claim 1 is in preparation treatment or prevention Qi deficiency blood stasis type cerebral infarction medicine Purposes.
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KR20200005907A (en) 2018-07-09 2020-01-17 숙명여자대학교산학협력단 Composition for neuroprotection containing extract or fraction of Prunus cerasoides as an effective component

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* Cited by examiner, † Cited by third party
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KR20200005907A (en) 2018-07-09 2020-01-17 숙명여자대학교산학협력단 Composition for neuroprotection containing extract or fraction of Prunus cerasoides as an effective component

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Application publication date: 20161123