CN107007528A - A kind of hair growth liquor and preparation method thereof - Google Patents
A kind of hair growth liquor and preparation method thereof Download PDFInfo
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- CN107007528A CN107007528A CN201710224465.9A CN201710224465A CN107007528A CN 107007528 A CN107007528 A CN 107007528A CN 201710224465 A CN201710224465 A CN 201710224465A CN 107007528 A CN107007528 A CN 107007528A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/24—Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
A kind of hair growth liquor, its raw material includes by weight：6 10 parts of Radix Angelicae Sinensis；7 11 parts of ginger；10 14 parts of the fleece-flower root；9 13 parts of safflower；59 parts of purslane；48 parts of dandelion；8 12 parts of ginkgo leaf；10 14 parts of mulberry root skin；48 parts of cacumen biotae；13 parts of lopseed；15 parts of white lilac；6 10 parts of peppermint；0.5 3 parts of feverfew；0.5 1.5 parts of ethanol, present invention simultaneously relates to the preparation method of hair growth liquor.Hair growth liquor that the present invention is provided and preparation method thereof, can effectively promote hair change blacking close, so that preferably protection hair portion health.
Description
Technical field
The present invention relates to cosmetic technical field, and in particular to a kind of hair growth liquor and preparation method thereof.
Background technology
Hair is the important component of human body, and it is grown in hair follicle, including the hair root inside hair follicle and is exposed at surface
Outer hair shaft.Hair can influence the overall image of people, and the people for possessing pitch-black dense hair often seems more healthy vigor.
The hair that normal person comes off daily is roughly the same with the quantity of new hair tonic, therefore will not be thinning.If alopecia quantity exceedes new life
The quantity of hair, and hair is than thinning as pathologic alopecia obvious in the past.If usually alopecia is few, but natural on-off cycles of hair growth delays very much
Slowly, hair is gradually dilute, falls within pathologic alopecia.
Causing the factor of pathologic alopecia has many, there is congenital or hereditary factors, also there is the sexual factor day after tomorrow；There is physiology
Property reason, also there is pathologic reason.Generally with acquired disposition, i.e. alopecia caused by some pathology sexual factors is most commonly seen, such as essence
Refreshing pressure is big, suffers from acute and chronic infectious disease, various skin diseases, endocrinopathy, chemical factors, neural factors, trophic factor etc.,
Alopecia can be caused.The method of hair growth is a lot.According to theory of traditional Chinese medical science, hair and liver kidney have a substantial connection, the main blood of kidney storing essence liver,
Its Hua Fa, then asthenia of essence and blood, the nutrition that hair follicle cannot be sufficient of liver kidney deficiency, a kind of situation is synthesis of melanin reduced capability,
There is white hair, then it is exactly hair follicle atrophy or necrosis to also have a kind of situation, causes alopecia.Conversely, liver kidney is strong, it is upper it is flourish in
Head, then hair is dense pitch-black.
It therefore, it can screen reasonable traditional Chinese medicinal components, design a kind of hair products for more effectively promoting hair change blacking close,
So as to which preferably protection hair portion is healthy.
The content of the invention
For defect of the prior art, present invention aims at a kind of hair growth liquor and preparation method thereof is provided, with effective
Promote hair tonic so that preferably protection hair portion health.
To achieve the above object, the technical scheme that provides of the present invention is：
A kind of hair growth liquor, its raw material includes by weight：
6-10 parts of Radix Angelicae Sinensis；
7-11 parts of ginger；
10-14 parts of the fleece-flower root；
9-13 parts of safflower；
5-9 parts of purslane；
4-8 parts of dandelion；
8-12 parts of ginkgo leaf；
10-14 parts of mulberry root skin；
4-8 parts of cacumen biotae；
1-3 parts of lopseed；
1-5 parts of white lilac；
6-10 parts of peppermint；
0.5-3 parts of feverfew；
0.5-1.5 parts of ethanol.
In the further embodiment of the present invention, appropriate water is also contained in the hair growth liquor.
In the further embodiment of the present invention, 0.1-0.3 parts of potassium sorbate is also contained in the hair growth liquor.
In the further embodiment of the present invention, its raw material includes by weight：
8 parts of Radix Angelicae Sinensis；
9 parts of ginger；
12 parts of the fleece-flower root；
11 parts of safflower；
7 parts of purslane；
6 parts of dandelion；
10 parts of ginkgo leaf；
12 parts of mulberry root skin；
6 parts of cacumen biotae；
2 parts of lopseed；
3 parts of white lilac；
8.8 parts of peppermint；
2 parts of feverfew；
0.2 part of potassium sorbate；
1 part of ethanol.
The hair growth liquor that the present invention is provided, mainly uses plurality of Chinese to be prepared as raw material, is below primary raw material
Abbreviated functional description：
Radix Angelicae Sinensis, nature and flavor are sweet, pungent, temperature, Return liver, the heart, the spleen channel, with replenishing and activating blood, and menstruction regulating and pain relieving relaxes bowel, can be very
Well along logical inside of human body, there is relatively good protective effect particularly with kidney, so as to play effect of hair tonic.
Ginger, it is pungent；It is warm-natured.Return lung, stomach, the spleen channel.It is warming channel and expelling cold, Back to Yang Tongmai, eliminating dampness dissolving phlegm.Blood medicine can be drawn and enter blood system,
Gas medicine enters qi leel, can go to dislike again and support new, has the meaning of Yin grows while yang is generating, the wherein main component of volatile oil contained by rhizome is zingiberol, ginger
Alkene, amphene, phellandium alkene, borneol, citral and by olein etc. promotes the blood circulation of scalp, improves the living environment of hair.
The fleece-flower root, containing nutritional ingredients such as lecithin, the work(with nourishing the blood to expel wind can adjust nerve and endocrine function,
Hairy root nourishing, promotes the generation of hair melanin, makes hair more black.Meanwhile, the fleece-flower root also contains Chrysophanol and much starch, forms sediment
After powder hydrolysis, glucose can be generated, is used with good profit breaking-out, is the optimal Chinese medicine material for preparing hair conditioner.
Safflower, nature and flavor：It is pungent, temperature.Channel tropism：Enter the heart, Liver Channel.With invigorate blood circulation, effect of stasis eliminatings analgesic.Controlling through closing, disease
Lump in the abdomen, difficult labour, stillborn foetus, disease that postpartum lochia can't go, hemostasis are had a pain, carbuncle swells, injury from falling down.In the present invention, work is cooperateed with other compositions
With the effect for play and conserve skin of head, aoxidizing hair growing hair follicle.
Purslane, containing abundant two oxyethylamines, malic acid, glucose, calcium, phosphorus, iron and vitamin E, carrotene,
The nutriments such as vitamin B, vitamin C.Nature and flavor acid, trembles with fear.With clearing heat and promoting diuresis, effect of removing pattogenic heat from the blood and toxic material from the body is used for this invention,
Play a part of suppressing pathogenic skin of head fungi.
Dandelion, it is bitter in taste, sweet, tremble with fear.Return liver, stomach.With clearing heat and detoxicating, dispersing swelling and dissipating binds, effect of inducing diuresis for treating strangurtia.Together
Sample, in the present invention, dandelion advances to heat-clearing, the effect of removing toxic substances to the growing environment of hair.
Contain Multiple components in ginkgo leaf, extract, mainly have flavonoids, terpene lactones, organic acid, organic alcohols,
Mineral matter, vitamin etc., wherein flavones are strong oxygen free radical scavengers, can protect Skin Cell not by oxygen radical mistake
Spend the influence of oxidation.Ginkgo biloba p.e is added in treatment can thoroughly remove pore depths dirt, in addition, ginkgo is extracted
Lactone thing in thing has broad-spectrum bactericidal action.
Mulberry root skin, nature and flavor slight bitter；It is cold in nature.Channel tropism Liver Channel.Major function heat-clearing is calmed the frightened；Dispelling wind and removing obstruction in the meridians.Main frightened epilepsy；Hot eyes；
Toothache；Arthralgia and myalgia.Inventor is had found, mulberry root skin is added in the present invention, can be acted synergistically with other compositions, play suppression
The effect of scalp fungi.
Cacumen biotae, it is bitter in taste, puckery, tremble with fear.Channel tropism return lung, liver, the spleen channel.Major function cooling blood and hemostasis, growing and blacking hair.For telling
Blood bleeding from five sense organs or subcutaneous tissue, spitting of blood, has blood in stool, metrostaxis, blood-head alopecia, poliosis.In the present invention, cacumen biotae plays the work(of growing and blacking hair
Effect.
Lopseed, nature and flavor leaf is pungent；It is warm-natured；It is poisonous.Channel tropism liver；Stomach.Major function dispelling wind and removing obstruction in the meridians；Analgesic；Stomach strengthening and digestion promoting；
Desinsection.Main arthralgia pain due to rheumatism；Indigestion；Vomiting；Cysticercosis；Eczema of scrotum；Sore and toxic.Its maintenance action to scalp exists
Synergistic application is able in the present invention.
Peppermint, nature and flavor are pungent, cool.Channel tropism return lung, Liver Channel.Major function dispelling wind-heat.Refresh oneself, promoting eruption.For wind-heat sense
Emit, wind-warm syndrome is from the beginning of headache, hot eyes, larynx numbness, aphtha, rubella, measles, Breast bilges frowsty about.
Feverfew, cold nature, sweet-bitter flavor.There is scattered wind heat-clearing, clear liver and improve vision and antiinflammation of detoxifying, volatile oil is contained in spending
0.13%th, chrysanthemum glucoside, adenine, choline, stachydrine and mcg vitamin A samples material, vitamin B, amino acid etc., strengthen blood capillary
Pipe resistance and bacteriostasis.
Potassium sorbate, as preservative, has no toxic side effect to human body.
The hair growth liquor that the present invention is provided, can effectively conserve skin of head and hair follicle, promote hair tonic so that hair becomes
Blacking is close, preferably protection hair portion health.
Second aspect, the invention provides the preparation method of hair growth liquor, comprises the following steps：
S1, the weighing fleece-flower root, cacumen biotae, and extracted respectively, obtain radix-polygoni multiflori extract and Cacumen Platycladi extract；
S2, by Radix Angelicae Sinensis, ginger, safflower, purslane, dandelion, ginkgo leaf, mulberry root skin, lopseed, white lilac, peppermint, little Bai
Chrysanthemum weighs corresponding parts by weight, is mixed, is ground into powder, powder is added to the water, while by radix-polygoni multiflori extract and side
CedarLeaves extract is sequentially added, and is then heated to 55~85 DEG C, is incubated 1~3 hour under agitation, then be cooled to normal temperature；
S3, the raw material after the cooling filtered, obtain filtrate；Potassium sorbate and second are added in the filtrate
Alcohol, is well mixed, and concentration is added as needed on appropriate water, vacuum preserves to obtain hair growth liquor.
The fleece-flower root uses following extracting method：Distilled water is added, solid-liquid ratio is 1：11-13, the refluxing extraction at 70 DEG C
1.5-3 hours, extract three times, merge extract solution, be concentrated under reduced pressure, obtain medicinal extract as radix-polygoni multiflori extract.
Cacumen biotae uses following extracting method：Cacumen biotae is weighed, the 27-30 times of distilled water measured is added, in immersion at 45 DEG C
45min, adds cellulase, pectase after cooling, and it is 5.0 to adjust pH value of solution, in water enzyme digestion 3 hours at 50 DEG C, enzymolysis
Regulation pH is neutrality afterwards, is extracted 2 times in constant temperature at 90 DEG C, is filtered, concentration, then using ethanol precipitation, small in standing 24 at 3 DEG C
When, centrifugation obtains sediment, as Cacumen Platycladi extract.
It is described to be ground into 30-50 mesh powders in step S2 in the further embodiment of the present invention.
In the further embodiment of the present invention, in step S2, the weight ratio of the powder and water is 1:1~1:3.
In the further embodiment of the present invention, in step S2, it is stirred with 60-80 revs/min of speed.
In the further embodiment of the present invention, in step S3, filtering uses 80~120 mesh sieves.
The present invention further embodiment in, in step S3, the concentration volume be concentrated into original volume 10~
30%.
The invention has the advantages that：
In the present invention, using cacumen biotae, the fleece-flower root as main ingredient, the direct effect of blackening and generating hair is played, remaining component plays logical
Through promoting blood circulation, the capillary of skin of head is expanded, accelerates blood circulation, nutrition hair follicle improves the growing environment of hair,
Furthermore it is also possible to play a part of the sterilization to scalp, sterilization, so as to improve the growing environment of hair, the effect of hair tonic is improved
Really.
The preparation method of the hair growth liquor provided using the present invention, is proposed for specific component, can be by each component
Active ingredient is fully extracted, and is played hair tonic, is conserved effect of scalp.
The additional aspect and advantage of the present invention will be set forth in part in the description, and will partly become from the following description
Obtain substantially, or recognized by the practice of the present invention.
Embodiment
The technical scheme in the embodiment of the present invention is clearly and completely described below, it is clear that described embodiment
Only a part of embodiment of the invention, rather than whole embodiments.Based on the embodiment in the present invention, the common skill in this area
The every other embodiment that art personnel are obtained under the premise of creative work is not made, belongs to the model that the present invention is protected
Enclose.
With reference to specific embodiment, the invention will be further described.
Embodiment 1
A kind of hair growth liquor, its raw material includes by weight：6 parts of Radix Angelicae Sinensis；7 parts of ginger；10 parts of the fleece-flower root；9 parts of safflower；Dent
5 parts of amaranth；4 parts of dandelion；8 parts of ginkgo leaf；10 parts of mulberry root skin；4 parts of cacumen biotae；1 part of lopseed；1 part of white lilac；6 parts of peppermint；It is small
0.5 part of feverfew；0.5 part of ethanol；Also contain 0.1 part of potassium sorbate in the hair growth liquor；In addition, also containing in right amount in hair growth liquor
Water carries out allotment concentration.
The preparation method of hair growth liquor, comprises the following steps：
S1, the weighing fleece-flower root, cacumen biotae, and extracted respectively, obtain radix-polygoni multiflori extract and Cacumen Platycladi extract；What
The tuber of multiflower knotweed uses following extracting method：Distilled water is added, solid-liquid ratio is 1：11, refluxing extraction 1.5 hours at 70 DEG C extract three
It is secondary, merge extract solution, be concentrated under reduced pressure, obtain medicinal extract as radix-polygoni multiflori extract；Cacumen biotae uses following extracting method：Weigh side
CedarLeaves, add the distilled water of 27 times of amounts, in soaking 45min at 45 DEG C, cellulase, pectase are added after cooling, and adjust molten
Liquid pH is 5.0, in water enzyme digestion 3 hours at 50 DEG C, and it is neutrality that pH is adjusted after enzymolysis, is extracted 2 times in constant temperature at 90 DEG C, filtering,
Concentration, then using ethanol precipitation, in standing 24 hours at 3 DEG C, centrifugation obtains sediment, as Cacumen Platycladi extract；
S2, by Radix Angelicae Sinensis, ginger, safflower, purslane, dandelion, ginkgo leaf, mulberry root skin, lopseed, white lilac, peppermint, little Bai
Chrysanthemum weighs corresponding parts by weight, is mixed, is ground into 30 mesh powders, powder is added to the water, while the fleece-flower root is extracted
Thing and Cacumen Platycladi extract are sequentially added, and are then heated to 55 DEG C, are incubated 1 hour under agitation, then be cooled to normal temperature；
S3, the raw material after the cooling filtered, filtering uses 80 mesh sieves, obtains filtrate；In the filtrate
Middle addition potassium sorbate and ethanol, are well mixed, are concentrated into the 10% of original volume, are added as needed on appropriate water, and vacuum is protected
Deposit to obtain hair growth liquor.
Embodiment 2
A kind of hair growth liquor, its raw material includes by weight：10 parts of Radix Angelicae Sinensis；11 parts of ginger；14 parts of the fleece-flower root；13 parts of safflower；
9 parts of purslane；8 parts of dandelion；12 parts of ginkgo leaf；14 parts of mulberry root skin；8 parts of cacumen biotae；3 parts of lopseed；5 parts of white lilac；Peppermint
10 parts；3 parts of feverfew；1.5 parts of ethanol；Also contain 0.3 part of potassium sorbate in the hair growth liquor；In addition, also containing in hair growth liquor
Appropriate water carries out allotment concentration.
The preparation method of hair growth liquor, comprises the following steps：
S1, the weighing fleece-flower root, cacumen biotae, and extracted respectively, obtain radix-polygoni multiflori extract and Cacumen Platycladi extract；What
The tuber of multiflower knotweed uses following extracting method：Distilled water is added, solid-liquid ratio is 1：13, refluxing extraction 3 hours at 70 DEG C are extracted three times,
Merge extract solution, be concentrated under reduced pressure, obtain medicinal extract as radix-polygoni multiflori extract；Cacumen biotae uses following extracting method：Weigh arbor-vitae
Leaf, adds the distilled water of 30 times of amounts, in soaking 45min at 45 DEG C, cellulase, pectase is added after cooling, and adjust solution
PH is 5.0, in water enzyme digestion 3 hours at 50 DEG C, and it is neutrality that pH is adjusted after enzymolysis, is extracted 2 times in constant temperature at 90 DEG C, and filtering is dense
Contracting, then using ethanol precipitation, in standing 24 hours at 3 DEG C, centrifugation obtains sediment, as Cacumen Platycladi extract；
S2, by Radix Angelicae Sinensis, ginger, safflower, purslane, dandelion, ginkgo leaf, mulberry root skin, lopseed, white lilac, peppermint, little Bai
Chrysanthemum weighs corresponding parts by weight, is mixed, is ground into 50 mesh powders, powder is added to the water, while the fleece-flower root is extracted
Thing and Cacumen Platycladi extract are sequentially added, and are then heated to 85 DEG C, are incubated 3 hours under agitation, then be cooled to normal temperature；
S3, the raw material after the cooling filtered, filtering uses 120 mesh sieves, obtains filtrate；In the filtrate
Middle addition potassium sorbate and ethanol, are well mixed, are concentrated into the 30% of original volume, are added as needed on appropriate water, and vacuum is protected
Deposit to obtain hair growth liquor.
Embodiment 3
A kind of hair growth liquor, its raw material includes by weight：8 parts of Radix Angelicae Sinensis；9 parts of ginger；12 parts of the fleece-flower root；11 parts of safflower；Horse
7 parts of bitterroot；6 parts of dandelion；10 parts of ginkgo leaf；12 parts of mulberry root skin；6 parts of cacumen biotae；2 parts of lopseed；3 parts of white lilac；Peppermint 8.8
Part；2 parts of feverfew；0.2 part of potassium sorbate；1 part of ethanol；Also allotment concentration is carried out in hair growth liquor containing appropriate water.
The preparation method of hair growth liquor, comprises the following steps：
S1, the weighing fleece-flower root, cacumen biotae, and extracted respectively, obtain radix-polygoni multiflori extract and Cacumen Platycladi extract；What
The tuber of multiflower knotweed uses following extracting method：Distilled water is added, solid-liquid ratio is 1：12, refluxing extraction 2 hours at 70 DEG C are extracted three times,
Merge extract solution, be concentrated under reduced pressure, obtain medicinal extract as radix-polygoni multiflori extract；Cacumen biotae uses following extracting method：Weigh arbor-vitae
Leaf, adds the distilled water of 28 times of amounts, in soaking 45min at 45 DEG C, cellulase, pectase is added after cooling, and adjust solution
PH is 5.0, in water enzyme digestion 3 hours at 50 DEG C, and it is neutrality that pH is adjusted after enzymolysis, is extracted 2 times in constant temperature at 90 DEG C, and filtering is dense
Contracting, then using ethanol precipitation, in standing 24 hours at 3 DEG C, centrifugation obtains sediment, as Cacumen Platycladi extract；
S2, by Radix Angelicae Sinensis, ginger, safflower, purslane, dandelion, ginkgo leaf, mulberry root skin, lopseed, white lilac, peppermint, little Bai
Chrysanthemum weighs corresponding parts by weight, is mixed, is ground into 40 mesh powders, powder is added to the water, while the fleece-flower root is extracted
Thing and Cacumen Platycladi extract are sequentially added, and are then heated to 70 DEG C, are incubated 2 hours under agitation, then be cooled to normal temperature；
S3, the raw material after the cooling filtered, filtering uses 100 mesh sieves, obtains filtrate；In the filtrate
Middle addition potassium sorbate and ethanol, are well mixed, are concentrated into the 20% of original volume, are added as needed on appropriate water, and vacuum is protected
Deposit to obtain hair growth liquor.
Embodiment 4
A kind of hair growth liquor, its raw material includes by weight：7 parts of Radix Angelicae Sinensis；8 parts of ginger；11 parts of the fleece-flower root；10 parts of safflower；Horse
6 parts of bitterroot；5 parts of dandelion；9 parts of ginkgo leaf；11 parts of mulberry root skin；5 parts of cacumen biotae；2 parts of lopseed；2 parts of white lilac；7 parts of peppermint；
0.8 part of feverfew；0.7 part of ethanol；Also contain 0.1 part of potassium sorbate in the hair growth liquor；In addition, also containing appropriate in hair growth liquor
Water carry out allotment concentration.
The preparation method of hair growth liquor, comprises the following steps：
S1, the weighing fleece-flower root, cacumen biotae, and extracted respectively, obtain radix-polygoni multiflori extract and Cacumen Platycladi extract；What
The tuber of multiflower knotweed uses following extracting method：Distilled water is added, solid-liquid ratio is 1：11, refluxing extraction 3 hours at 70 DEG C are extracted three times,
Merge extract solution, be concentrated under reduced pressure, obtain medicinal extract as radix-polygoni multiflori extract；Cacumen biotae uses following extracting method：Weigh arbor-vitae
Leaf, adds the distilled water of 28 times of amounts, in soaking 45min at 45 DEG C, cellulase, pectase is added after cooling, and adjust solution
PH is 5.0, in water enzyme digestion 3 hours at 50 DEG C, and it is neutrality that pH is adjusted after enzymolysis, is extracted 2 times in constant temperature at 90 DEG C, and filtering is dense
Contracting, then using ethanol precipitation, in standing 24 hours at 3 DEG C, centrifugation obtains sediment, as Cacumen Platycladi extract；
S2, by Radix Angelicae Sinensis, ginger, safflower, purslane, dandelion, ginkgo leaf, mulberry root skin, lopseed, white lilac, peppermint, little Bai
Chrysanthemum weighs corresponding parts by weight, is mixed, is ground into 35 mesh powders, powder is added to the water, while the fleece-flower root is extracted
Thing and Cacumen Platycladi extract are sequentially added, and are then heated to 60 DEG C, are incubated 1.5 hours under agitation, then be cooled to normal temperature；
S3, the raw material after the cooling filtered, filtering uses 90 mesh sieves, obtains filtrate；In the filtrate
Middle addition potassium sorbate and ethanol, are well mixed, are concentrated into the 15% of original volume, are added as needed on appropriate water, and vacuum is protected
Deposit to obtain hair growth liquor.
Embodiment 5
A kind of hair growth liquor, its raw material includes by weight：9 parts of Radix Angelicae Sinensis；10 parts of ginger；13 parts of the fleece-flower root；12 parts of safflower；Horse
8 parts of bitterroot；7 parts of dandelion；11 parts of ginkgo leaf；13 parts of mulberry root skin；7 parts of cacumen biotae；2.5 parts of lopseed；4 parts of white lilac；Peppermint 9
Part；2.5 parts of feverfew；1.2 parts of ethanol；Also contain 0.3 part of potassium sorbate in the hair growth liquor；In addition, also containing in hair growth liquor
Appropriate water carries out allotment concentration.
The preparation method of hair growth liquor, comprises the following steps：
S1, the weighing fleece-flower root, cacumen biotae, and extracted respectively, obtain radix-polygoni multiflori extract and Cacumen Platycladi extract；What
The tuber of multiflower knotweed uses following extracting method：Distilled water is added, solid-liquid ratio is 1：13, refluxing extraction 1.5 hours at 70 DEG C extract three
It is secondary, merge extract solution, be concentrated under reduced pressure, obtain medicinal extract as radix-polygoni multiflori extract；Cacumen biotae uses following extracting method：Weigh side
CedarLeaves, add the distilled water of 30 times of amounts, in soaking 45min at 45 DEG C, cellulase, pectase are added after cooling, and adjust molten
Liquid pH is 5.0, in water enzyme digestion 3 hours at 50 DEG C, and it is neutrality that pH is adjusted after enzymolysis, is extracted 2 times in constant temperature at 90 DEG C, filtering,
Concentration, then using ethanol precipitation, in standing 24 hours at 3 DEG C, centrifugation obtains sediment, as Cacumen Platycladi extract；
S2, by Radix Angelicae Sinensis, ginger, safflower, purslane, dandelion, ginkgo leaf, mulberry root skin, lopseed, white lilac, peppermint, little Bai
Chrysanthemum weighs corresponding parts by weight, is mixed, is ground into 45 mesh powders, powder is added to the water, while the fleece-flower root is extracted
Thing and Cacumen Platycladi extract are sequentially added, and are then heated to 80 DEG C, are incubated 2.5 hours under agitation, then be cooled to normal temperature；
S3, the raw material after the cooling filtered, filtering uses 120 mesh sieves, obtains filtrate；In the filtrate
Middle addition potassium sorbate and ethanol, are well mixed, are concentrated into the 25% of original volume, are added as needed on appropriate water, and vacuum is protected
Deposit to obtain hair growth liquor.
Hair growth liquor prepared by the embodiment of the present invention 1 to embodiment 5 carries out pharmacodynamic study, and with certain hair tonic on the market
Essence is control group, and specific method and result are as follows：
1st, to the influence of depilation mouse hair regeneration
Method：70 mouse back barium sulphides are lost hair or feathers, depilation area be 3cm × 3cm, be then randomly divided into A, B, C,
Seven groups of D, E, F, G, every group 10.The corresponding materials of 2ml are smeared in mouse back depilation skin predetermined region：A groups are smeared
The hair growth liquor that embodiment 1 is prepared, B groups smear the hair growth liquor that embodiment 2 is prepared, and C groups are smeared embodiment 3 and prepared
Hair growth liquor, D groups smear the hair growth liquor for preparing of embodiment 4, and E groups smear the hair growth liquor that embodiment 5 is prepared, the painting of F groups
Smearing certain hair tonic Essence on the market, as a control group, G groups smear water as a control group, and every mouse is smeared once for every two days.
As a result：In each mouse hair removal section after certain time, the quantity of new piliation is counted clearly, and removes 20 new lives at random
Hair, its length is surveyed with micrometer, is averaged under the microscope, compares each group hair growth difference.Concrete outcome such as table 1 below
It is shown：
Table 1 uses each group mouse hair growing state after Essence
It was found from result above, after the hair growth liquor using the present invention, the growth of each group mouse hair is preferable, and with making
With the growth of time, effect is more obvious.After continuous use 6 months, the mean elements of E groups can reach 90, and average length is
89.34 ± 12.86mm, the growing state than other groups is all good, particularly with the F using certain growing and blacking hair Essence on the market
Group, the mean elements of hair is only capable of reaching 55, and average length is only 60.87 ± 10.22mm.And contrasting A-E group results can
Know, hair growth liquor effect prepared by C groups (embodiment 3) is more preferable.Result above shows that hair growth liquor prepared by the present invention can be with trophonema
Capsule, promotes hair hyperplasia, effectively plays a part of generating and nourishing hair.
2nd, the influence sent out experimenter all living creatures
Subject's selection standard and packet：Hair sparse, the people of subject 280 of partial exfoliation are chosen, 14 groups are classified as,
It is respectively：Each 10 people of men and women of 30-40 Sui is A1 groups, and each 10 people of men and women of 30-40 Sui is B1 groups, the men and women each 10 of 30-40 Sui
Artificial C1 groups, each 10 people of men and women of 30-40 Sui is D1 groups, and each 10 people of men and women of 30-40 Sui is E1 groups, and the men and women of 30-40 Sui is each
10 people are F1 groups, and each 10 people of men and women of 30-40 Sui is G1 groups；Each 10 people of men and women of 40-50 Sui is A2 groups, the men and women of 40-50 Sui
Each 10 people is B2 groups, and each 10 people of men and women of 40-50 Sui is C2 groups, and each 10 people of men and women of 40-50 Sui is D2 groups, the man of 40-50 Sui
Each 10 people of female is E2 groups, and each 10 people of men and women of 40-50 Sui is F2 groups, and each 10 people of men and women of 40-50 Sui is G2 groups.
Test products and application method：Using a test products, and every time, consumption was identical in 3 days by all subjects, was
The corresponding products of 2ml：A groups smear the hair growth liquor that embodiment 1 is prepared, and B groups smear the hair growth liquor that embodiment 2 is prepared, C
Group smears the hair growth liquor that embodiment 3 is prepared, and D groups smear the hair growth liquor that embodiment 4 is prepared, and E groups are smeared embodiment 5 and made
Standby obtained hair growth liquor, F groups smear certain growing and blacking hair Essence on the market, and as a control group, G groups smear water as a control group, even
It is continuous to use 6 months.
As a result：Before subject's head is divided into, in, left and right, rear five regions, position respectively, respectively choose 1cm2Standard
Point takes hair radical average value as measurement position.After product, the hair number in the region is obtained flat as stated above
Average, will be subtracted using the hair radical average value before product using the hair radical average value after product, divided by using production
Hair radical average value before product, calculates the growth ratio of hair number, then calculates the growth of the hair number of all subjects of this group
Ratio average is recorded in following table, specific as shown in table 2：
Table 2 uses the growth ratio mean conditions of each group subject's hair number before and after hair growth liquor
It was found from result above, after the hair growth liquor using the present invention, the growth ratio of hair number is larger, continuously makes
After 6 months, for the subject of 30-40 Sui, the growth ratio of hair number is 152%-169%, and is used on the market
Certain hair tonic Essence, the growth ratio of hair number is only 93%；For the subject of 40-50 Sui, the growth ratio of hair number
Example is 133%-151%, and uses certain growing and blacking hair Essence on the market, and the growth ratio of hair number is only 82%.And it is right
Understood than A-E groups result, hair growth liquor effect prepared by embodiment 3 is more preferable.Result above shows that hair growth liquor prepared by the present invention can
To nourish hair follicle, promote hair hyperplasia, effectively play the effect of generating and nourishing hair.
Although embodiments of the invention have been shown and described above, it is to be understood that above-described embodiment is example
Property, it is impossible to limitation of the present invention is interpreted as, one of ordinary skill in the art within the scope of the invention can be to above-mentioned
Embodiment is changed, changed, replacing and modification, and the essence of appropriate technical solution is departed from various embodiments of the present invention skill
The scope of art scheme, it all should cover among the claim of the present invention and the scope of specification.
Claims (9)
1. a kind of hair growth liquor, it is characterised in that its raw material includes by weight：
6-10 parts of Radix Angelicae Sinensis；
7-11 parts of ginger；
10-14 parts of the fleece-flower root；
9-13 parts of safflower；
5-9 parts of purslane；
4-8 parts of dandelion；
8-12 parts of ginkgo leaf；
10-14 parts of mulberry root skin；
4-8 parts of cacumen biotae；
1-3 parts of lopseed；
1-5 parts of white lilac；
6-10 parts of peppermint；
0.5-3 parts of feverfew；
0.5-1.5 parts of ethanol.
2. a kind of hair growth liquor as claimed in claim 1, it is characterised in that also contain potassium sorbate 0.1- in the hair growth liquor
0.3 part.
3. a kind of hair growth liquor as claimed in claim 2, it is characterised in that its raw material includes by weight：
8 parts of Radix Angelicae Sinensis；
9 parts of ginger；
12 parts of the fleece-flower root；
11 parts of safflower；
7 parts of purslane；
6 parts of dandelion；
10 parts of ginkgo leaf；
12 parts of mulberry root skin；
6 parts of cacumen biotae；
2 parts of lopseed；
3 parts of white lilac；
8.8 parts of peppermint；
2 parts of feverfew；
0.2 part of potassium sorbate；
1 part of ethanol.
4. prepare the method for hair growth liquor as claimed in claim 2, it is characterised in that comprise the following steps：
S1, the weighing fleece-flower root, cacumen biotae, and extracted respectively, obtain radix-polygoni multiflori extract and Cacumen Platycladi extract；
S2, Radix Angelicae Sinensis, ginger, safflower, purslane, dandelion, ginkgo leaf, mulberry root skin, lopseed, white lilac, peppermint, feverfew claimed
Corresponding parts by weight are measured, are mixed, powder is ground into, powder is added to the water, while by radix-polygoni multiflori extract and cacumen biotae
Extract is sequentially added, and is then heated to 55~85 DEG C, is incubated 1~3 hour under agitation, then be cooled to normal temperature；
S3, the raw material after the cooling filtered, obtain filtrate；Potassium sorbate and ethanol are added in the filtrate, is mixed
Close uniform, concentration is added as needed on appropriate water, vacuum preserves to obtain hair growth liquor.
5. the preparation method of hair growth liquor as claimed in claim 4, it is characterised in that in step S2, described to be ground into 30-50 purposes
Powder.
6. the preparation method of hair growth liquor as claimed in claim 4, it is characterised in that in step S2, the weight of the powder and water
Than for 1:1~1:3.
7. the preparation method of hair growth liquor as claimed in claim 4, it is characterised in that in step S2, with 60-80 revs/min of speed
Rate is stirred.
8. the preparation method of hair growth liquor as claimed in claim 4, it is characterised in that in step S3, filtering uses 80~120
Mesh sieve.
9. the preparation method of hair growth liquor as claimed in claim 4, it is characterised in that in step S3, the concentration volume is concentration
To the 10~30% of original volume.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114983882A (en) * | 2022-05-05 | 2022-09-02 | 上海沁丝堂生物医药科技有限公司 | Hair nourishing liquid with alopecia preventing effect and preparation method thereof |
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|---|---|---|---|---|
| CN102218112A (en) * | 2010-04-15 | 2011-10-19 | 耿德华 | Formula of Chinese herbal medicine for lipsotrichia stopping and hair growth and preparation method thereof |
| CN103054776A (en) * | 2013-01-08 | 2013-04-24 | 李鹏 | Functional traditional Chinese medicinal stock shampoo and its preparation method |
| CN103479989A (en) * | 2013-09-29 | 2014-01-01 | 蔡铭成 | Natural composite anti-hair-loss hair-growing liquid for external use |
| CN104043066A (en) * | 2013-03-14 | 2014-09-17 | 纪廷璜 | Chinese herbal extract for promoting hair growth and hair blacking and improving dandruff and application thereof |
| CN105412854A (en) * | 2014-09-18 | 2016-03-23 | 重庆鼎升生物科技有限公司 | Hair growth liquid and preparation method thereof |
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2017
- 2017-04-07 CN CN201710224465.9A patent/CN107007528A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102218112A (en) * | 2010-04-15 | 2011-10-19 | 耿德华 | Formula of Chinese herbal medicine for lipsotrichia stopping and hair growth and preparation method thereof |
| CN103054776A (en) * | 2013-01-08 | 2013-04-24 | 李鹏 | Functional traditional Chinese medicinal stock shampoo and its preparation method |
| CN104043066A (en) * | 2013-03-14 | 2014-09-17 | 纪廷璜 | Chinese herbal extract for promoting hair growth and hair blacking and improving dandruff and application thereof |
| CN103479989A (en) * | 2013-09-29 | 2014-01-01 | 蔡铭成 | Natural composite anti-hair-loss hair-growing liquid for external use |
| CN105412854A (en) * | 2014-09-18 | 2016-03-23 | 重庆鼎升生物科技有限公司 | Hair growth liquid and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114983882A (en) * | 2022-05-05 | 2022-09-02 | 上海沁丝堂生物医药科技有限公司 | Hair nourishing liquid with alopecia preventing effect and preparation method thereof |
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Application publication date: 20170804 |