CN107375387A - A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of oriental wormwood - Google Patents
A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of oriental wormwood Download PDFInfo
- Publication number
- CN107375387A CN107375387A CN201710738826.1A CN201710738826A CN107375387A CN 107375387 A CN107375387 A CN 107375387A CN 201710738826 A CN201710738826 A CN 201710738826A CN 107375387 A CN107375387 A CN 107375387A
- Authority
- CN
- China
- Prior art keywords
- oriental wormwood
- squeezing
- vacuum drying
- fresh
- drying powder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of oriental wormwood.The technique is cleaned, eluted after the harvesting of oriental wormwood medicinal material, and takes advantage of fresh squeezing, leaching concoction.The dregs of a decoction add water stirring, filtering squeezing.Gained concoction is concentrated under reduced pressure after merging, and is dried in vacuo, is vacuum-packed after crushing.Virgate Wormwood Herb medicine materical crude slice prepared by this method, remains the polarity in medicinal material and nonpolar active ingredient to greatest extent.Medicine materical crude slice is beneficial to accumulating, and convenient to adjust, quality controllable, curative effect is reliable, to ensureing that tcm clinical curative effect has great importance.The promotion and implementation of this law, will there are significant social effect and economic benefit.
Description
Technical field
The invention belongs to Chinese medicine manufacture field, more particularly to the processing technology of Chinese medicine capillaris tablet.
Background technology
Chinese medicine oriental wormwood is feverfew Artemisia capillarisArtemisia capillarisThunb. seedling.All herbal medicine, can
Flu-prevention, control heatstroke, flu, headache body weight, stomachache, vomiting, fullness in chest, vapour lock food stagnation, infantile indigestion with food retention abdominal distension, diarrhoea,
Under menorrhalgia, uterine bleeding band, the disease such as skin itching and oedema.Function is delivered in its radiating, is better than peppermint especially.
The processing mode of conventional capillaris tablet is:After harvesting, impurity is removed, is dried, directly packing storage and transport.This
Dry oriental wormwood Hygienic Index can not be up to standard a bit, and medicinal material easily occurs and goes mouldy, so as to cause the decline of medical material quanlity and clinic
The reduction of curative effect.Such prepared herbal medicine in small pieces ready for decoction, it is bulky, easily occur it is rotten and contaminated, quality it is difficult to ensure that, be unfavorable for adjustment and match somebody with somebody
Just and ensure its clinical efficacy.
At present, in the market also has the manufactured granule pieces sale after extraction of oriental wormwood medicinal material.The preparation of granule pieces
Journey, extraction not only time consumption and energy consumption, and do solvent because commonly using substantial amounts of water, the nonpolar active ingredient in medicinal material is difficult to be extracted
Out.Further, since the oriental wormwood medicinal material of extraction is also to dry and by storage for a long time, therefore, the loss of active ingredient
It is and very big.In order to ensure the clinic of oriental wormwood medicinal material is effective, steady quality, a kind of new capillaris tablet and its preparation technology
Urgently develop.
The content of the invention
The invention discloses " a kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of oriental wormwood ".This technique can be maximum
The polarity and the nonpolar active ingredient that retain in oriental wormwood medicinal material of limit, avoid medicinal material from being processed and storage and transport process in existing medicine materical crude slice
In the loss of caused active ingredient and the decline of medical material quanlity, reduce medicinal material by mould etc. pollution, to ensuring capillaris tablet
Steady quality and clinical safety effectively have great importance.
To achieve these goals, the technical scheme is that:
Its herb is gathered in oriental wormwood picking time, is cleaned, after washing, takes advantage of fresh squeezing.In the dregs of a decoction after squeezing, 1 ~ 5 times of amount of addition
Water, 5 ~ 30min is stirred, juice is taken with plate and frame filter press press filtration.The remaining dregs of a decoction press extracting juice again.Merge concoction three times, with 40 ~ 120
Mesh screen, obtain oriental wormwood concoction.By obtained oriental wormwood concoction be concentrated under reduced pressure under the conditions of 40 ~ 75 DEG C relative density for 1.05 ~
1.30 medicinal extract, and 60 ~ 120 mesh sieves are crushed after it is dried in vacuo 4 ~ 8 hours in 40 ~ 70 DEG C, it is vacuum-packed, produces oriental wormwood
It is fresh to squeeze vacuum drying powder decoction pieces.
On the label of product packaging bags, the name of an article in printing, medicinal part, planting site, medicine materical crude slice manufacturer, the date of manufacture,
The information such as Contents of Main Components, meridian distribution of property and flavor, major function, usage and dosage, toxic side effect and contraindication.Oriental wormwood is enclosed in bag
Thin layer differentiates collection of illustrative plates and/or efficient liquid phase characteristic spectrum, " identity card " as product.In addition, in the packaging bag of product, print
There is Quick Response Code, former plant photo, medicinal material photo, medicine materical crude slice photo, character and the micro- mirror for obtaining product can be linked by scanning
The information such as other feature.
The present invention is advantageous in that:
The oriental wormwood medicinal material of fresh collection, clean and directly squeezed after washing, filter, be concentrated under reduced pressure, being dried in vacuo, resulting powder
Medicine materical crude slice, the active ingredient in medicinal material can be retained to greatest extent.This medicine materical crude slice volume compared to traditional medicine materical crude slice volume greatly
Reduce, vacuum packaging so that prepared slice quality is more stable, is adjusted beneficial to accumulating and clinic, has very significant social effect
And economic implications.
Embodiment
Embodiment 1
By the oriental wormwood medicinal material of fresh collection, clean, silt is washed with water, take advantage of using fresh herb squeezer pressure extracting juice.The gained dregs of a decoction add 3 times
The drinking water of amount, stir 20min, plate and frame filter press pressure extracting juice.The remaining dregs of a decoction press extracting juice with squeezer again.By above-mentioned 3
Secondary concoction merges, with 100 mesh sieve net filtrations.Filtrate decompression concentrates, and temperature is set as 65 DEG C.In medicinal extract relative density obtained by concentration
For 1.15 when, be transferred in vacuum drying chamber, in 60 DEG C dry 8 hours, low-temperature grinding, moisture be not higher than 12%.
Embodiment 2
By the oriental wormwood medicinal material of fresh collection, clean, silt is washed with water, take advantage of using fresh herb squeezer pressure extracting juice.The gained dregs of a decoction add 5 times
The drinking water of amount, stir 30min, plate and frame filter press pressure extracting juice.The remaining dregs of a decoction press extracting juice with squeezer again.By above-mentioned 3
Secondary concoction merges, with 80 mesh sieve net filtrations.Filtrate decompression concentrates, and temperature is set as 70 DEG C.In medicinal extract relative density obtained by concentration
For 1.10 when, be transferred in vacuum drying chamber, in 65 DEG C dry 6 hours, low-temperature grinding, moisture be not higher than 12%.
Above example, only illustrate the technological thought of this invention, it is impossible to it is all whereby to limit protection scope of the present invention
It is any change for being done on the basis of technical scheme according to technological thought proposed by the present invention, each falls within what the present invention protected
Within the scope of.
Claims (2)
- A kind of 1. fresh preparation technology for squeezing vacuum drying powder decoction pieces of oriental wormwood, it is characterised in that:It is complete that its is gathered in oriental wormwood picking time Grass, clean, after washing, take advantage of fresh squeezing, the dregs of a decoction add the water of 1 ~ 5 times of amount, stir 5 ~ 30min, and plate and frame filter press press filtration takes juice, institute The surplus dregs of a decoction press extracting juice again, merge concoction three times, 40 ~ 120 mesh screens, obtain oriental wormwood concoction.
- A kind of 2. fresh preparation technology for squeezing vacuum drying powder decoction pieces of oriental wormwood according to claim 1, it is characterised in that:Will Obtained oriental wormwood concoction is concentrated under reduced pressure into the medicinal extract that relative density is 1.05 ~ 1.30 under the conditions of 40 ~ 75 DEG C, and by its in 40 ~ 70 DEG C vacuum drying 4 ~ 8 hours after crushed 60 ~ 120 mesh sieves, be vacuum-packed, produce oriental wormwood it is fresh squeeze vacuum drying powder decoction pieces.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710738826.1A CN107375387A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of oriental wormwood |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710738826.1A CN107375387A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of oriental wormwood |
Publications (1)
Publication Number | Publication Date |
---|---|
CN107375387A true CN107375387A (en) | 2017-11-24 |
Family
ID=60346849
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710738826.1A Withdrawn CN107375387A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of oriental wormwood |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN107375387A (en) |
-
2017
- 2017-08-25 CN CN201710738826.1A patent/CN107375387A/en not_active Withdrawn
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PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WW01 | Invention patent application withdrawn after publication | ||
WW01 | Invention patent application withdrawn after publication |
Application publication date: 20171124 |