CN107375158A - A kind of NMF and its application - Google Patents
A kind of NMF and its application Download PDFInfo
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- CN107375158A CN107375158A CN201710478422.3A CN201710478422A CN107375158A CN 107375158 A CN107375158 A CN 107375158A CN 201710478422 A CN201710478422 A CN 201710478422A CN 107375158 A CN107375158 A CN 107375158A
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- slag
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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Abstract
The invention discloses a kind of NMF and its application, the NMF is made up of following mass percent component：Naked oat bran extracts slag 0.1 2.5%, cod skin extraction slag 0.3 3.2%, peanut coat extraction slag 0.2 2.1%.The NMF is applied in foundation emulsion, skin hyaluronic acid amount can be effectively increased, supplements the collagen in skin, strengthens the moistening effect of skin.
Description
Technical field
The present invention relates to cosmetic field, and in particular to a kind of NMF and its application.
Background technology
Foundation emulsion is the foundation cream of liquid, and foundation emulsion can obstruct dust in air etc. and enter skin, therefore plays protection and make
With, can also pin the moisture in skin, be moistened skin, be most show consideration for skin one layer of coat.Existing foundation emulsion
Moistening effect is undesirable, it is impossible to pins moisture well, skin cannot moisten so that skin is coarse, aging, or even produces wrinkle
Line.
Some commercially available foundation emulsions are coated onto airtight on the face, easily block pore, and easily dry, and therefore, it is a kind of to be badly in need of exploitation
Foundation emulsion with lasting moisturizing moisturizing effect.
The content of the invention
For prior art, it is an object of the invention to provide a kind of NMF and its application, and the NMF is applied to
In foundation emulsion, there is lasting moisturizing and other effects.
To achieve the above object, the present invention uses following scheme：
A kind of NMF extracts slag by Naked oat bran, cod skin extracts slag and peanut coat extraction slag forms.
Further, the mass percent of the Naked oat bran extraction slag, cod skin extraction slag and peanut coat extraction slag
It is as follows：Naked oat bran extracts slag 0.1-2.5%, cod skin extraction slag 0.3-3.2%, peanut coat extraction slag 0.2-2.1%.
Preferably, the mass percent of described Naked oat bran extraction slag, cod skin extraction slag and peanut coat extraction slag
It is as follows：Naked oat bran extracts slag 0.2-2.0%, cod skin extraction slag 0.5-2.5%, peanut coat extraction slag 0.5-1.6%.
Optimal, described Naked oat bran extraction slag, cod skin extraction slag and peanut coat extracts the mass percent of slag
It is as follows：Naked oat bran extracts slag 1.5%, cod skin extraction slag 1.2%, peanut coat extraction slag 1.1%.
A kind of preparation method of NMF is as follows：After collecting Naked oat bran, cod skin, the extracted utilization of peanut coat raw material
Residuum feedstocks, be then dried respectively, be respectively crushed into 10-15 mesh, finally mixed according to aforementioned proportion.
Further, the residue of described Naked oat bran, peanut coat raw material after extraction and application refers to naked oat bran
Skin and peanut coat raw material carry by one or more techniques in alcohol extracting, water extraction, oil immersion formulation, supercritical carbon dioxide extraction method
Take rear left residue；Residue after the extracted utilization of described cod skin refers to cod skin by hot-water process, alkaline process, salt
Left residue after one or more techniques extraction in method, enzymatic isolation method.
The present invention also provides a kind of application of NMF in cosmetics are prepared, and the cosmetics are foundation emulsion.
Further, described foundation emulsion includes the component of following mass percent：Above-mentioned NMF 0.5-7.8%,
Glycerine 8-13%, propane diols 6-12%, ring five dimethyl silicone polymer 4-10%, dimethyl silicone polymer 2-5%, bentonite
3.5-8.7%, isopropyl palmitate 3.2-6.5%, caprylic/capric triglyceride 2.5-6.4%, vaseline 3.4-6.5%, dioxy
Change titanium 4-7.8%, hyaluronic acid 0.1-0.3%, jojoba seed oil 0.3-1.0%, sodium chloride 0.01-0.03%, methyl hydroxybenzoate
0.06-0.1%, Nipasol 0.0.2-0.13%, essence 0.01-0.05%, deionized water surplus.
Several compositions in the plant residue composition used in the present invention are introduced below：
The oat of China's cultivation is based on naked grain type, referred to as naked oats.Naked oat bran is extracted rear remaining residue still
Remain its distinctive active component protein, beta glucan.Beta glucan is the main dietary fiber in oat bran, is had important
Physiological function.Oat beta-glucan has the function that enhancing is immune, by stimulating immunity of organism, can excite the immune system of skin
And make Skin Cell from the injury of ultraviolet, the generation of collagen between fibrocyte can be facilitated indirectly, so as to induce skin
Skin recombinates.With performance of keeping humidity, cell culture test shows, using 1% oat extract, can measure intracellular hyaluronic acid amount
Obvious increase, hyaluronic acid amount number can be used for judging the power of skin moisture-keeping ability.Oat protein hydrolysate contains abundant
Balanced amino acid, can effectively pin moisture, have significant moist, nutritive effect, particularly for Dry, and
And property is quite gentle, it is not easy to causes skin allergy or stimulation.Oat polypeptide has extremely excellent moisture-keeping efficacy, experiment
Determine its moisture-keeping function long stable effect；Contain substantial amounts of hydrophilic group in collagen molecules, can reach and make skin keep moist
Purpose.Two kinds of albumen collective effects have more permeability to skin, and with more the effect of supplement skin collagen, can strengthen
The Water-saving effect of skin, fundamentally the problem of improvement dry skin, balance skin.Oat polypeptide has good moistening effect,
Can assign skin moisten, smooth touch, and oat polypeptide can suppress the activity of collagen catabolic enzyme, increase in skin
The content of collagen, so as to safeguard that skin structure matter is complete, keep skin elasticity.
Cod skin is extracted rear remaining residue and also has its peculiar activity-collagen.Collagen has good
Moisturizing and skin-care effect, are in particular in the following aspects：(1) collagen contains hydrophilic NMF, and
The powerful pinning moisture of triple-helix structure energy, the skin moment is allowed to keep the tender state of moistening, water；(2) active collagen is to skin
Permeability it is strong, can pass through cuticula is combined with skin epithelial cell, participation and improvement Skin Cell metabolism, make in skin
Collagen activity is strengthened.It can keep the integrality of cuticula moisture and fibre structure, improve Skin Cell living environment and
Promote the metabolism of skin histology, strengthen blood circulation, reach the purpose of skin care；(3) the good water conservation of collagen
Ability makes skin water profit glossy, distributes the brilliance of health；(4) after collagen is absorbed by the skin, be filled in dermis of skin it
Between, increase skin tight ness rating, produce skin tension, reduce pore, make skin tight and high resilience.Plentiful collagen in corium
Albumin layer, Skin Cell is propped up, with reference to moisturizing and the effect of suppression wrinkle, reach the work(unfolded coarse groove, desalinate microgroove jointly
Effect；(5) when molecular mass is 300~500u, active collagen can directly penetrate into skin bottom, and affine with surrounding tissue
Property it is good, can helper cell manufacture collagen, promote Skin Cell normal growth；(6) active collagen also has disappear in itself
Scorching and renewal skin effect.
Peanut coat is the kind skin of legume peanut, sweet, slight bitter, mild-natured, there is styptic powder addiction, the work(of detumescence.It is modern
Pharmacological research shows there is anastalsis, and clinical report has obvious haemostatic effect to a variety of haemorrhages, but its hemostatic mechanism and has
It is unclear to imitate composition.It is reported that contain lipid in peanut coat, stay the horizontal matter of liquor-saturated, burnt property catechol-type and a small amount of Chu Piao fens and peanut
Military, leucocyanidin and leucodelphindin.Peanut coat extract shows that it can be indirect to the inhibitory action of hyaluronidase
Increase the content of skin hyaluronic acid.
Compared with prior art, it is the device have the advantages that as follows：(1) naked swallow is used in foundation cream liquid product of the present invention
Wheat bran skin extraction slag, cod skin extraction slag and peanut coat extract slag compounding use in specific proportions, by increasing skin hyalomitome
Acid amount, supplements the collagen in skin, strengthens the moistening effect of skin.(2) wherein naked oats extraction slag and peanut coat extract
Slag cooperative effect, increase skin hyaluronic acid contents, while cod skin extraction slag cooperates with work with the compound of naked oats extraction slag
With, permeability is had more to skin, with more supplement skin collagen effect, make in skin collagen activity strengthen.
Collagen can keep the integrality of cuticula moisture and fibre structure, improve Skin Cell living environment and promote skin histology
Metabolism, strengthen blood circulation, reach the purpose of skin care；After collagen is absorbed by the skin, skin is filled in
Between corium, increase skin tight ness rating, produce skin tension, reduce pore, make skin tight and high resilience.It is plentiful in corium
Collagen layer, Skin Cell is propped up, with reference to moisturizing and suppresses the effect of wrinkle, reaches that to unfold coarse groove, desalination thin jointly
The effect of line.(3) product of the present invention acts synergistically to reach mainly using also there being the distinctive active component of its raw material in residue
To the effect of moisturizing.These residues are effectively utilized, turns waste into wealth, reduces production cost, improve the utilization rate of plant material,
And preparation technology is simple.
Embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated：
All the components appeared in text are INCI (InternationalNomenclatureCosmeticIngredi
Ent), i.e., international cosmetic raw material is obviously said to its defined title.
The embodiment 1~5 of foundation emulsion of the present invention is formulated, and is shown in Table 1.
Table 1
The preparation method of NMF is as follows：
The residuum feedstocks after Naked oat bran, cod skin, the extracted utilization of peanut coat raw material are collected, are then done respectively
It is dry, 10-15 mesh is respectively crushed into, is finally mixed according to aforementioned proportion.
Comparative example 1：
Naked oat bran extraction slag is not added in difference with embodiment 3 only, remaining each material addition, preparation condition and work
Skill does not change.
Comparative example 2：
Cod skin extraction slag is not added in difference with embodiment 3 only, remaining each material addition, and conditions and technology of preparation is equal
Do not change.
Comparative example 3：
Peanut coat extraction slag is not added in difference with embodiment 3 only, remaining each material addition, and conditions and technology of preparation is equal
Do not change.
Comparative example 4：
Compared with Example 3, Naked oat bran extraction slag, cod skin extraction slag, peanut coat extraction slag do not add, remaining
Each material addition, conditions and technology of preparation do not change still.
Using effect is verified：
The people of volunteer 16 tested intentionally is recruited at random, and it is the women between 19~44, by continuous 2 time-of-week, often
8 points or so of its morning, each sentence on the inside of the right arm wrist 2mg/cm2 dosage uniformly smear and be formulated by embodiment 3 made of
Sample.In 6 points or so same every indexes of detection every afternoon.
Detection index method：Machine testing skin moisture and skin elasticity are tested using MC760 Multi-functional skins.
The data of the change of the moisture of the relevant skin of instrument test and elasticity are collected and handled.I.e.：It will survey
The data obtained are changed and calibrated through hundred-mark system, obtain data as shown in table 2.
Calibration equation：The difference of the data of the data of N days=same day right arm left arm same area+be not used before left arm number
According to
Table 2
| Foundation emulsion | Before experiment | 1 day | 3 days | 7 days | 14 days |
| Moisture | 42.4 | 44.3 | 48.1 | 49.3 | 50.5 |
| Water loss | 49.6 | 45.7 | 38.3 | 37.1 | 35.5 |
| Elasticity | 85.5 | 86.7 | 87.7 | 88.5 | 89.7 |
From table 2 it can be seen that the foundation emulsion sample that with the addition of the present composition can effectively supplement moisture of skin, water is reduced
Shunting is lost, and slowly strengthens skin elasticity.
Above example is merely to illustrate embodiment of the present invention, does not have any formal limit to the present invention
System；It is any to be engaged in professional and technical personnel, all have the ability using the technology contents having revealed that, some are made to it and changes or repaiies
Decorations, turn into the equivalent embodiment of equivalent variations.According to the technology of the present invention essence, simply modification, equivalent variations are carried out to the present invention
With modification, belong in the range of technical solution of the present invention.
Claims (9)
1. a kind of NMF, it is characterised in that described NMF extracts slag by Naked oat bran, cod skin extracts slag and peanut
Clothing extraction slag composition.
2. a kind of NMF according to claim 1, it is characterised in that the Naked oat bran extraction slag, cod skin carry
Take the mass percent of slag and peanut coat extraction slag as follows：
Naked oat bran extraction slag 0.1-2.5%
Cod skin extraction slag 0.3-3.2%
Peanut coat extraction slag 0.2-2.1%.
3. a kind of NMF according to claim 2, it is characterised in that described Naked oat bran extracts slag, cod skin
The mass percent for extracting slag and peanut coat extraction slag is as follows：
Naked oat bran extraction slag 0.2-2.0%
Cod skin extraction slag 0.5-2.5%
Peanut coat extraction slag 0.5-1.6%.
4. a kind of NMF according to claim 3, it is characterised in that described Naked oat bran extracts slag, cod skin
The mass percent for extracting slag and peanut coat extraction slag is as follows：
Naked oat bran extracts slag 1.5%
Cod skin extracts slag 1.2%
Peanut coat extracts slag 1.1%.
5. according to a kind of NMF described in claim any one of 1-4, it is characterised in that the preparation method of described NMF
It is as follows：The residuum feedstocks after Naked oat bran, cod skin, the extracted utilization of peanut coat raw material are collected, are then dried respectively,
10-15 mesh is respectively crushed into, is finally mixed according to aforementioned proportion.
6. a kind of NMF according to claim 5, it is characterised in that described Naked oat bran, peanut coat raw material warp
The residue crossed after extraction and application refers to Naked oat bran and peanut coat raw material by alcohol extracting, water extraction, oil immersion formulation, overcritical dioxy
Change residue left after one or more techniques in carbon extraction are extracted；Residue after the extracted utilization of described cod skin
Refer to cod skin residue left after one or more techniques extraction in hot-water process, alkaline process, salt method, enzymatic isolation method.
A kind of 7. application of the NMF according to claim any one of 1-6 in cosmetics are prepared.
8. application according to claim 7, it is characterised in that described cosmetics are foundation emulsion.
9. a kind of foundation emulsion of humidity-preserving type, it is characterised in that described foundation emulsion includes the component of following mass percent：Such as power
Profit requires NMF 3.8% described in 1, glycerine 8-13%, propane diols 6-12%, ring five dimethyl silicone polymer 4-10%, poly-
Dimethyl siloxane 2-5%, bentonite 3.5-8.7%, isopropyl palmitate 3.2-6.5%, caprylic/capric triglyceride 2.5-
6.4%th, vaseline 3.4-6.5%, titanium dioxide 4-7.8%, hyaluronic acid 0.1-0.3%, jojoba seed oil 0.3-1.0%, chlorine
Change sodium 0.01-0.03%, methyl hydroxybenzoate 0.06-0.1%, Nipasol 0.0.2-0.13%, essence 0.01-0.05%, go from
Sub- water surplus.
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| CN201710478422.3A CN107375158A (en) | 2017-06-21 | 2017-06-21 | A kind of NMF and its application |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710478422.3A CN107375158A (en) | 2017-06-21 | 2017-06-21 | A kind of NMF and its application |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107375166A (en) * | 2017-07-18 | 2017-11-24 | 佛山实瑞先导材料研究院（普通合伙） | A kind of NMF and its application |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107375166A (en) * | 2017-07-18 | 2017-11-24 | 佛山实瑞先导材料研究院（普通合伙） | A kind of NMF and its application |
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