CN107375135A - A kind of preparation method of Chinese herbal medicine whitening and spot eliminating cream - Google Patents
A kind of preparation method of Chinese herbal medicine whitening and spot eliminating cream Download PDFInfo
- Publication number
- CN107375135A CN107375135A CN201710631520.6A CN201710631520A CN107375135A CN 107375135 A CN107375135 A CN 107375135A CN 201710631520 A CN201710631520 A CN 201710631520A CN 107375135 A CN107375135 A CN 107375135A
- Authority
- CN
- China
- Prior art keywords
- parts
- herbal medicine
- chinese herbal
- homogeneous
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Abstract
The present invention relates to a kind of preparation method of Chinese herbal medicine whitening and spot eliminating cream, by extracts of Chinese herbal medicine or suspension extracts of Chinese herbal medicine, emulsifying agent, NMF, nourishing agent, thickener, pearling agent, essence and water be added in homogenizer it is at least homogeneous once, the homogeneous thing of gained is Chinese herbal medicine whitening and spot eliminating cream.The effect of present invention has whitening, sun-proof, moisturizing and nourishes skin.
Description
Technical field
The present invention relates to a kind of preparation method of Chinese herbal medicine whitening and spot eliminating cream.
Background technology
With the popularization of electrical equipment, we come into contacts with more and more with electrical equipment, and the electromagnetic wave discharged during electric operation is to human body
Skin lesion is very big, contacts for a long time and easily causes color spot, inflammation, accelerate skin aging, destroy human immune system, influences people
Body health.
The many whitening and spot eliminating creams of in the market are blent using chemokine class and formed, and effect is fine in the short time, but for a long time
Using easily causing the skin sex chromosome mosaicism such as acne, acne, troublesome.
Chinese herbal medicine whitening spot-removing has safe and effective advantage, increasingly obtains the attention of people.
The content of the invention
The technical problem to be solved by the invention is to provide a kind of preparation method of Chinese herbal medicine whitening and spot eliminating cream, has U.S.
In vain, nti-freckle and nourish skin the effect of.
In order to solve the above-mentioned technical problem, the present invention uses following technical scheme：
A kind of preparation method of Chinese herbal medicine whitening and spot eliminating cream, it is characterised in that：
By extracts of Chinese herbal medicine or suspension extracts of Chinese herbal medicine, emulsifying agent, NMF, nourishing agent, thickener, pearling agent,
Essence and water are according to mass ratio 5~95:2~90:0~60:0~60:0~10:0~50:0~5:0~93 is added to homogenizer
In, temperature be 50~80 DEG C, pressure be 2~45MPa under the conditions of at least it is homogeneous once, the homogeneous thing of gained is Chinese herbal medicine whitening
Content in freckle cream；
The emulsifying agent is polyglyceryl fatty acid ester, lauric monoglyceride, methyl glycol fatty acid ester, sorbitol anhydride list palm fibre
Glycerin monostearate, stearoyl lactate, diacetyl tartarate monoglyceride, NPE, polyoxyethylene oleic acid ester, tristearin
Sour polyoxyethylene ester, sorbitan fatty acid ester, two polyglycereol, diisooctyl Succinate sodium sulfonate and aliphatic acid polyoxy second
One or any ratio in alkene fat it is two or more；
The NMF is glycerine, fructose, propane diols, sorbierite, polyglutamic acid, niacinamide, polyethylene glycol and xylitol
In one or any ratio it is two or more；
The nourishing agent is honey, sodium salicylate, superoxide dismutase, Alphalin, beta glucan, vitamin e, bad ammonia
One or any ratio in sour sodium and vitamin E it is two or more；
The pearling agent be pearl powder, stearic acid diethylene glycol dilaurate, one kind in ethylene glycol double stearic acid and mica powder or
Person's arbitrary proportion it is two or more；
The thickener is one kind in sodium chloride, sodium carboxymethylcellulose, gelatin, sodium alginate and casein or appointed
Meaning ratio it is two or more；
The extracts of Chinese herbal medicine, is followed the steps below：
1) herbal composite is prepared：5~20 parts of the bletilla striata, 5~20 parts of the bighead atractylodes rhizome, the root of Dahurain angelica 5~20 are weighed according to parts by weight
2~10 parts of part, 5~20 parts of PORIA ALBA, 5~20 parts of radix ampelopsis, Amomum cardamomum 5~20,5~20 parts of rhizoma typhonii and centella, in obtaining
Herbal-composition；
2) product A is prepared：Herbal composite is added in juice extractor and squeezed the juice, gained juice is product A；
3) product B is prepared：The residue for having squeezed juice is added in stirred tank, and adds solvent, the quality of residue and solvent
Than for 1:2~15, it is 60~100 DEG C in temperature, under the conditions of pressure is 0~5MPa, stirring decocts 20~120min, obtains product
B；
4) products C is prepared：Merge product A and B, and sterilized, obtain products C；
5) extracts of Chinese herbal medicine is prepared：Products C is added in homogenizer, under the conditions of temperature is 50~80 DEG C, at least
It is homogeneous once, it is homogeneous after gained suspension be suspension herbal medicine extract solution；Or products C is filtered, gained filtrate is
Extracts of Chinese herbal medicine；
The solvent is the two or more of one kind in water, ethanol, sorbierite, Span-80 and glycerine or arbitrary proportion.
Homogeneous all for twice in the homogenizer, wherein first time homogeneous pressure be 15~35MPa, the homogeneous time for 10~
60min；Second of homogeneous pressure is 2~8PMa, and the homogeneous time is 10~60min.
Chinese herbal medicine plucking time described in step 1) is plucked for early morning summer；The fresh bletilla striata 10 is weighed according to parts by weight
4 parts of part, 7 parts of the bighead atractylodes rhizome, 6 parts of the root of Dahurain angelica, 12 parts of PORIA ALBA, 6 parts of radix ampelopsis, 7 parts of Amomum cardamomum, 7 parts of rhizoma typhonii and centella.
Step 3) the solvent is water and ethanol according to mass ratio 4:1 composition；The mass ratio of residue and solvent is 1:
5, decocted 40 minutes at 85 DEG C.
Step 4) the sterilising conditions are 70~120 DEG C, 0~10MPa of pressure, 20~60min of sterilization time of temperature.
The emulsifying agent is polyglyceryl fatty acid ester, lauric monoglyceride and sorbitol anhydride monopalmitate according to quality
Than 3:2:2 composition；The NMF is glycerine, fructose and polyglutamic acid according to mass ratio 1:2:2 composition；The taste
Tonic is honey, superoxide dismutase and vitamin E according to mass ratio 2:1:1 composition；The pearling agent is pearl powder
With stearic acid diethylene glycol dilaurate according to mass ratio 5:1 composition；The thickener is sodium chloride；Extracts of Chinese herbal medicine, emulsification
Agent, NMF, nourishing agent, thickener, pearling agent, the mass ratio of essence and water are 50:5:10:15:0.5:9:0.5:10.
The bletilla striata, (scientific name：Bletilla striata) also known as Lian Jicao, Gan Gen, give free of charge, indocalamus orchid, Zhu Lan, purple blue, purple a species of orchid,
Hundred large bamboo hats with a conical crown and broad brim, Pseudobulbus Bletillae (Rhizoma Bletillae), Cold boiled chicken baby, Bai Gen, YANGJIAOQI.Major function：Astringing to arrest bleeding, detumescence and promoting granulation.Spitted blood for hemoptysis, wound goes out
Blood, sore swollen toxin, chapped skin；Pulmonary tuberculosis hemoptysis, ulcer haemorrhage.
The bighead atractylodes rhizome, Classification system Atractylodes macrocephala.Alias small wooden raft Ji, Yu Shu, the winter bighead atractylodes rhizome, wash rice art, poplar
Small wooden raft, Wu Shu, piece art, rhizoma atractylodis etc., belong to composite family, [WTBX herbaceos perennial.With strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis,
The effect of antiabortive.
The root of Dahurain angelica (Latin literary fame：Angelica dahurica(Fisch.ex Hoffm.)Benth.et Hook.f.ex
Franch.et Sav), perennial tall and big draft, high 1-2.5 rice, root is cylindrical, and 2-5 centimetres of basal part of stem footpath, basal leaf one returns plumage
Shape divides, universal umbel basidixed or side life, fruit Long Circle to oval.Get rid of illness dehumidifying, apocenosis myogenic, promoting blood circulation and stopping pain etc.
Effect.
PORIA ALBA (scientific name：Smilax china), also known as：Buddha's warrior attendant pocket, scabrousstem greenbrier rhizome etc., belong to Liliales.With internal heat anticance,
The effect of sharp aquation drink, strengthening the spleen and reducing phlegm, antitoxic heart-soothing and sedative.
Radix ampelopsis, also known as mountain region melon, wild sweet potato, V. amurensis seedling, Bai Gen, five pawl rattans etc., it is the drying of vitaceae radix ampelopsis
Root tuber.With clearing heat and detoxicating；Eliminating stagnation to stop pain；The effect of myogenic sore.
Amomum cardamomum is zingiberaceous plant, also known as boniness, and shell is cool, White Chloe, and hundred kowtow, and kowtow benevolence, has dampness elimination promoting the circulation of qi；Warming middle energizer to arrest vomiting；
The effect of appetite-stimulating indigestion-relieving.Pharmacological action：1. bacteriostasis：The shell decoction flat board trench method of product 100%, has suppression to shigella dysenteriae
Make and use.2. antiasthmatic effect：α-terpineol contained by the product, antiasthmatic effect is stronger, to guinea pig tracheal smooth muscle 0.05ml/kg agent
During amount, effect is better than Blumea oil.3. the fragrant stomach invigorating of tool, wind dispelling effect：Cardamom oil is very unstable, even if storage is fine, also Chang Yi
Its peculiar fragrance is lost, can typically be made fragrant tincture or spirit.Seed can should ground before use, have good fragrance to be good for
Stomach acts on, and can promote gastric secretion, excited intestinal motility, drive away enteral pneumatosis, and suppress enteral abnormal fermentation.4. suppress to make
With：Amomum cardamomum decoction is excited to guinea pig in vitro intestinal tube low concentration；Higher than 1% and volatile oil saturated aqueous solution is in inhibitory action.
5. other are acted on：Its volatile oil can strengthen the effect of low dose of streptomysin to guinea pig experimental tuberculosis.
Rhizoma typhonii, also known as Typhonium giganteum, milk are attached in vain.With wind-dispelling phlegm, arresting convulsion is jerked, detoxicating and resolving a mass, the effect of analgesic.Accumulated snow
Careless (scientific name：Centella asiatica (L.) Urban), also known as copper coin grass, membranaceous marshmarigold herb, money tooth grass etc..All herbal medicine, heat-clearing
Dampness removing, subdhing swelling and detoxicating, control acute diseases such as cholera and sunstroke xenon stomachache, heat rushes down, the leaching of dysentery, jaundice with damp-heat pathogen, sand, blood strangury, tell, blood, hemoptysis, hot eyes, larynx are swollen, wind
Rash, mange, malignant boil carbuncle swells poison, traumatic injury etc..The long-lived medicine of Asians, can beneficial brain refresh oneself.Research shows to have nourishing, disappeared
Inflammation, healing of wound, diuresis defaecation and calm effect.It is also effective in cure to leprosy, ulcer, there is activation to blood purification and immunity
Effect, because it can stimulate the replacement of deep skin cell.It is neural nourishing agent, can improve memory, mitigates mental fatigue；Also
Can hypotensive, treatment hepatopathy etc..
Invention has following advantageous effects：
1st, the fresh Chinese herbal medicine of the present invention preferably early morning summer harvesting is extract.Plant daytime based on photosynthesis,
Assimilation is carried out, at night based on respiration, dissimilation is carried out, organic macromolecule is converted into small molecule.Namely
Say, early morning harvesting, the small molecule in plant is most, and activity is best, it is easier to extracts, and is more beneficial for absorbing.Spring medium-height grass
Medicine is just sprouted, and the efficacy of a drug is inadequate, and fiber increases in autumn Chinese herbal medicine, extract relative difficulty, summer it is best.
2nd, the present invention combines extraction using squeezing and boiling two ways, is not added with any chemical composition, protects to greatest extent
Demonstrate,prove the natural sex of extract.
3rd, the present invention using homogenizer to extract carry out it is homogeneous, make effect suspension stabilization, will not precipitate, and it is homogeneous after
Chinese herbal medicine residue particles it is small, easily cleaning.
4th, the present invention uses eight kinds of combined Chinese herbs, and whitening spot-removing effect protrudes, and has no side effect.
5th, the present invention adds centella, and centella can stimulate the replacement of deep skin cell, special to whitening spot-removing effect
It is good.
Embodiment
The present invention is further illustrated with reference to instantiation.
Embodiment 1
By extracts of Chinese herbal medicine, emulsifying agent, NMF, nourishing agent, thickener, pearling agent, essence and water according to mass ratio
50:5:10:15:0.5:9:0.5:10 are added in homogenizer, and homogeneous under the conditions of being 55 DEG C in temperature is twice, wherein for the first time
Homogeneous pressure is 25MPa, and the homogeneous time is 25min；Second of homogeneous pressure is 4PMa, and the homogeneous time is 20min, and gained is homogeneous
Thing is Chinese herbal medicine whitening and spot eliminating cream.
The preparation technology of extracts of Chinese herbal medicine, is followed the steps below：
1) herbal composite is prepared：Fresh 10 parts of bletilla striata stem tuber, 7 parts of bighead atractylodes rhizome rhizome, the root of Dahurain angelica are weighed according to parts by weight
4 parts of 6 parts of rhizome, 12 parts of PORIA ALBA rhizome, 6 parts of radix ampelopsis rhizome, 7 parts of Amomum cardamomum, 7 parts of rhizoma typhonii stem tuber and centella, in obtaining
Herbal-composition.
2) product A is prepared：Herbal composite is added in juice extractor and squeezed the juice, gained juice is product A；
3) product B is prepared：The residue for having squeezed juice is added in stirred tank, and adds water and 95% industrial alcohol, it is residual
The mass ratio of slag, water and 95% industrial alcohol is 1:4:1,40min is decocted in 85 DEG C of stirrings, obtains product B；
4) products C is prepared：Merge product A and B, sterilize 30min at 80 DEG C, obtains products C；
5) extracts of Chinese herbal medicine is prepared：Products C is filtered, gained filtrate is extracts of Chinese herbal medicine.
Embodiment 2
By suspension extracts of Chinese herbal medicine, emulsifying agent, NMF, nourishing agent, thickener, pearling agent, essence and water according to matter
Measure ratio 20:15:10:20:0.5:3:0.2:41.3 are added in homogenizer, homogeneous for twice under the conditions of being 55 DEG C in temperature, its
Middle first time homogeneous pressure is 25MPa, and the homogeneous time is 25min；Second of homogeneous pressure is 4PMa, and the homogeneous time is 20min,
The homogeneous thing of gained is Chinese herbal medicine whitening and spot eliminating cream.
The preparation technology of suspension extracts of Chinese herbal medicine, is followed the steps below：
1) herbal composite is prepared：Fresh 6 parts of bletilla striata stem tuber, 9 parts of bighead atractylodes rhizome rhizome, root of Dahurain angelica root are weighed according to parts by weight
5 parts of 10 parts of stem, 7 parts of PORIA ALBA rhizome, 9 parts of radix ampelopsis rhizome, 10 parts of Amomum cardamomum, 8 parts of rhizoma typhonii stem tuber and centella, obtain medium-height grass
Drug composition.
2) product A is prepared：Herbal composite is added in juice extractor and squeezed the juice, gained juice is product A；
3) product B is prepared：The residue for having squeezed juice is added in stirred tank, and adds water, the mass ratio of residue and water is
1:4, at 85 DEG C, stirring decoction 40min, obtains product B under the conditions of 1MPa；
4) products C is prepared：Merge product A and B, at 80 DEG C, under the conditions of 2MPa, sterilize 30min, obtains products C；
5) suspension extracts of Chinese herbal medicine is prepared：Products C is added in homogenizer, it is homogeneous under the conditions of temperature is 65 DEG C
Secondary, wherein first time homogeneous pressure is 22MPa, and the homogeneous time is 20min；Second of homogeneous pressure is 4PMa, the homogeneous time
For 20min, homogeneous rear gained suspension is suspension extracts of Chinese herbal medicine.
Embodiment 3
By extracts of Chinese herbal medicine, emulsifying agent, NMF, nourishing agent, thickener, pearling agent, essence and water according to mass ratio
30:7:8:15:1:3:0.5:35.5 are added in homogenizer, temperature be 55 DEG C under the conditions of it is homogeneous once, homogeneous pressure is
25MPa, homogeneous time are 25min, and the homogeneous thing of gained is Chinese herbal medicine whitening and spot eliminating cream.
The preparation technology of extracts of Chinese herbal medicine, is followed the steps below：
1) herbal composite is prepared：Fresh 10 parts of bletilla striata stem tuber, 7 parts of bighead atractylodes rhizome rhizome, the root of Dahurain angelica are weighed according to parts by weight
4 parts of 6 parts of rhizome, 12 parts of PORIA ALBA rhizome, 6 parts of radix ampelopsis rhizome, 15 parts of Amomum cardamomum, 7 parts of rhizoma typhonii stem tuber and centella, in obtaining
Herbal-composition.
2) product A is prepared：Herbal composite is added in juice extractor and squeezed the juice, gained juice is product A；
3) product B is prepared：The residue for having squeezed juice is added in stirred tank, and adds water and 95% industrial alcohol, it is residual
The mass ratio of slag, water and 95% industrial alcohol is 1:3:1,40min is decocted in 85 DEG C of stirrings, obtains product B；
4) products C is prepared：Merge product A and B, sterilize 30min at 90 DEG C, obtains products C；
5) extracts of Chinese herbal medicine is prepared：Products C is filtered, gained filtrate is extracts of Chinese herbal medicine.
Embodiment 4
By suspension extracts of Chinese herbal medicine and emulsifying agent according to mass ratio 85:15 are added in homogenizer, are 55 DEG C in temperature
Under the conditions of it is homogeneous for twice, wherein first time homogeneous pressure is 25MPa, and the homogeneous time is 25min；Second of homogeneous pressure be
4PMa, homogeneous time are 20min, and the homogeneous thing of gained is Chinese herbal medicine whitening and spot eliminating cream.
The preparation technology of suspension extracts of Chinese herbal medicine, is followed the steps below：
1) herbal composite is prepared：Fresh 10 parts of bletilla striata stem tuber, 7 parts of bighead atractylodes rhizome rhizome, the root of Dahurain angelica are weighed according to parts by weight
4 parts of 6 parts of rhizome, 12 parts of PORIA ALBA rhizome, 6 parts of radix ampelopsis rhizome, 18 parts of Amomum cardamomum, 7 parts of rhizoma typhonii stem tuber and centella, in obtaining
Herbal-composition.
2) product A is prepared：Herbal composite is added in juice extractor and squeezed the juice, gained juice is product A；
3) product B is prepared：The residue for having squeezed juice is added in stirred tank, and adds water and 95% industrial alcohol, it is residual
The mass ratio of slag, water and 95% industrial alcohol is 1:4:1,40min is decocted in 85 DEG C of stirrings, obtains product B；
4) products C is prepared：Merge product A and B, sterilize 30min at 80 DEG C, obtains products C；
5) suspension extracts of Chinese herbal medicine is prepared：Products C is added in homogenizer, it is homogeneous under the conditions of temperature is 65 DEG C
Once, homogeneous pressure 30MPa, homogeneous time are 20min, and homogeneous rear gained suspension is suspension extracts of Chinese herbal medicine.
Embodiment 5
By extracts of Chinese herbal medicine, emulsifying agent, NMF, nourishing agent, thickener, pearling agent, essence and water according to mass ratio
50:5:10:15:0.5:9:0.5:10 are added in homogenizer, and homogeneous under the conditions of being 55 DEG C in temperature is twice, wherein for the first time
Homogeneous pressure is 25MPa, and the homogeneous time is 25min；Second of homogeneous pressure is 4PMa, and the homogeneous time is 20min, and gained is homogeneous
Thing is Chinese herbal medicine whitening and spot eliminating cream.
The preparation technology of extracts of Chinese herbal medicine, is followed the steps below：
1) herbal composite is prepared：According to parts by weight weigh 7 parts of 10 parts of bletilla striata stem tuber, bighead atractylodes rhizome rhizome after drying,
4 parts of 6 parts of root of Dahurain angelica rhizome, 12 parts of PORIA ALBA rhizome, 6 parts of radix ampelopsis rhizome, 7 parts of Amomum cardamomum, 7 parts of rhizoma typhonii stem tuber and centella, obtain
To herbal composite.
2) product A is prepared：Herbal composite is ground, gained powder is product A；
3) product B is prepared：Powder after grinding is added in stirred tank, and adds water and 95% industrial alcohol, powder
The mass ratio at end, water and 95% industrial alcohol is 1:4:1,40min is decocted in 85 DEG C of stirrings, obtains product B；
4) extracts of Chinese herbal medicine is prepared：Product B is filtered, gained filtrate is extracts of Chinese herbal medicine.
In embodiment 1 to 5, the emulsifying agent is polyglyceryl fatty acid ester, lauric monoglyceride and sorbitol anhydride list palm fibre
Glycerin monostearate is according to mass ratio 3:2:2 composition；The NMF is glycerine, fructose and polyglutamic acid according to mass ratio 1:2:2
Composition；The nourishing agent is honey, superoxide dismutase and vitamin E according to mass ratio 2:1:1 composition；It is described
Pearling agent is pearl powder and stearic acid diethylene glycol dilaurate according to mass ratio 5:1 composition；The thickener is sodium chloride.
Beneficial effects of the present invention are further illustrated with reference to experimental data：
First, test in laboratory：
1st, experimental method：Using tyrosine as substrate, using Dopachrome assay, common skin care item are determined at 490nm (except not
Add extracts of Chinese herbal medicine outside, other preparation methods are consistent with embodiment 1), embodiment 1, embodiment 2, embodiment 3, embodiment 4
Inhibitory action with embodiment 5 to tyrosinase activity.
2nd, experimental result：Common skin care item (in addition to extracts of Chinese herbal medicine is not added, other preparation methods and embodiment 1 one
Cause), embodiment 1, embodiment 2, embodiment 3, embodiment 4 and embodiment 5 be respectively with respect to the inhibiting rate of tyrosinase
52.32%th, 96.34%, 72.28%, 88.45%, 90.12% and 87.32%.
What melanin had generated main influence is tyrosinase, sees that the present invention is suppressing junket ammonia by above-mentioned experimental result
Mill run is substantially better than in terms of sour enzyme, the wherein inhibition of embodiment 1 is optimal.
2nd, actual experiment
1st, general information
Inventor selects 600 volunteers use product of the present invention between in July, 2015~2016 year July, wherein male
Property, each 300 of women, the range of age be 22~40 years old.Universal symptom is intensely dark skin, foxiness or blackspot.By this
600 experimenters are divided into 4 groups immediately, every group of 150 people, test respectively common skin care item (in addition to extracts of Chinese herbal medicine is not added, its
Its preparation method is consistent with embodiment 1), experiment 1 (in extracts of Chinese herbal medicine in addition to centella is not added, other preparation methods with
Embodiment 1 is consistent), embodiment 5 and embodiment 1.
2nd, test method
Sooner or later respectively smear once, use 4 months in face.
3rd, judgment criteria and evaluation result
3.1 judgment criteria
Evaluated using Lab colorimeter systems, be divided into recovery from illness：Foxiness or blackspot disappear, whiteness of skin；Take a turn for the better：Foxiness or
Blackspot is thin out, whiteness of skin；It is invalid：Foxiness or blackspot are unchanged, and skin is unchanged.
3.2 evaluation results statistics such as table 1.
13 groups of Comparison of therapeutic of table
| Group | Fully recover (example) | Take a turn for the better (example) | Invalid (example) | Total effective rate (%) | Adverse reaction |
| Common skin care item | 29 | 72 | 49 | 67.3 | Have |
| Experiment 1 | 34 | 77 | 39 | 74 | Nothing |
| Embodiment 1 | 79 | 63 | 8 | 94.7 | Nothing |
| Embodiment 5 | 37 | 86 | 27 | 82 | Nothing |
It can be seen that the present invention is significantly better than common skin care item in terms of beautifying whitening by the data of table 1, addition is using fresh
The effect of embodiment 1 of extract solution for preparing of Chinese herbal medicine be better than the embodiment 5 of extract solution prepared by the Chinese herbal medicine that dries of addition, product
The addition of snow grass can be obviously improved whitening spot-removing effect.
Claims (6)
- A kind of 1. preparation method of Chinese herbal medicine whitening and spot eliminating cream, it is characterised in that：By extracts of Chinese herbal medicine or suspension extracts of Chinese herbal medicine, emulsifying agent, NMF, nourishing agent, thickener, pearling agent, essence With water according to mass ratio 5~95:2~90:0~60:0~60:0~10:0~50:0~5:0~93 is added in homogenizer, Temperature be 50~80 DEG C, pressure be 2~45MPa under the conditions of at least it is homogeneous once, the homogeneous thing of gained is Chinese herbal medicine whitening spot-removing Frost；The emulsifying agent is polyglyceryl fatty acid ester, lauric monoglyceride, methyl glycol fatty acid ester, sorbitol anhydride list palmitic acid Ester, stearoyl lactate, diacetyl tartarate monoglyceride, NPE, polyoxyethylene oleic acid ester, stearic acid gather Oxygen vinyl acetate, sorbitan fatty acid ester, two polyglycereol, diisooctyl Succinate sodium sulfonate and aliphatic acid polyethenoxy fat In one or any ratio it is two or more；The NMF is in glycerine, fructose, propane diols, sorbierite, polyglutamic acid, niacinamide, polyethylene glycol and xylitol One or any ratio it is two or more；The nourishing agent is honey, sodium salicylate, superoxide dismutase, Alphalin, beta glucan, vitamin e, Sodium lysinate It is two or more with the one or any ratio in vitamin E；The pearling agent is pearl powder, stearic acid diethylene glycol dilaurate, one kind in ethylene glycol double stearic acid and mica powder or appointed Meaning ratio it is two or more；The thickener is the one or any ratio in sodium chloride, sodium carboxymethylcellulose, gelatin, sodium alginate and casein Example it is two or more；The extracts of Chinese herbal medicine, is followed the steps below：1）Prepare herbal composite：5~20 parts of the bletilla striata, 5~20 parts of the bighead atractylodes rhizome, 5~20 parts of the root of Dahurain angelica, white is weighed according to parts by weight 2~10 parts of 5~20 parts of Poria cocos, 5~20 parts of radix ampelopsis, Amomum cardamomum 5~20,5~20 parts of rhizoma typhonii and centella, obtain Chinese herbal medicine group Compound；2）Prepare product A：Herbal composite is added in juice extractor and squeezed the juice, gained juice is product A；3）Prepare product B：The residue for having squeezed juice is added in stirred tank, and adds solvent, the mass ratio of residue and solvent is 1:2~15, it is 60~100 DEG C in temperature, under the conditions of pressure is 0~5MPa, stirring decocts 20~120min, obtains product B；4）Prepare products C：Merge product A and B, and sterilized, obtain products C；5）Prepare extracts of Chinese herbal medicine：Products C is added in homogenizer, it is at least homogeneous under the conditions of temperature is 50~80 DEG C Once, homogeneous rear gained suspension is suspension herbal medicine extract solution；Or products C is filtered, gained filtrate is medium-height grass Medicament extracting solution；The solvent is the two or more of one kind in water, ethanol, sorbierite, Span-80 and glycerine or arbitrary proportion.
- 2. the preparation method of Chinese herbal medicine whitening and spot eliminating cream as claimed in claim 1, it is characterised in that：It is homogeneous in the homogenizer All for twice, wherein first time homogeneous pressure is 15~35MPa, and the homogeneous time is 10~60min；Second of homogeneous pressure is 2 ~8PMa, homogeneous time are 10~60min.
- 3. the preparation method of Chinese herbal medicine whitening and spot eliminating cream as claimed in claim 1, it is characterised in that：Step 1）Described in medium-height grass Medicine plucking time is plucked for early morning summer；Fresh 10 parts of the bletilla striata, 7 parts of the bighead atractylodes rhizome, 6 parts of the root of Dahurain angelica, PORIA ALBA are weighed according to parts by weight 4 parts of 12 parts, 6 parts of radix ampelopsis, 7 parts of Amomum cardamomum, 7 parts of rhizoma typhonii and centella.
- 4. the preparation method of Chinese herbal medicine whitening and spot eliminating cream as claimed in claim 1, it is characterised in that：Step 3）The solvent is Water and ethanol are according to mass ratio 4:1 composition；The mass ratio of residue and solvent is 1:5, decocted 40 minutes at 85 DEG C.
- 5. the preparation method of Chinese herbal medicine whitening and spot eliminating cream as claimed in claim 1, it is characterised in that：Step 4）The sterilizing bar Part is 70~120 DEG C, 0~10MPa of pressure, 20~60min of sterilization time of temperature.
- 6. the preparation method of Chinese herbal medicine whitening and spot eliminating cream as claimed in claim 1, it is characterised in that：The emulsifying agent is poly- sweet Oil and fat acid esters, lauric monoglyceride and sorbitol anhydride monopalmitate are according to mass ratio 3:2:2 composition；The moisturizing Agent is glycerine, fructose and polyglutamic acid according to mass ratio 1:2:2 composition；The nourishing agent is honey, superoxide dismutase Enzyme and vitamin E are according to mass ratio 2:1:1 composition；The pearling agent be pearl powder and stearic acid diethylene glycol dilaurate according to Mass ratio 5:1 composition；The thickener is sodium chloride；Extracts of Chinese herbal medicine, emulsifying agent, NMF, nourishing agent, thickening Agent, pearling agent, the mass ratio of essence and water are 50:5:10:15:0.5:9:0.5:10.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710631520.6A CN107375135A (en) | 2017-07-28 | 2017-07-28 | A kind of preparation method of Chinese herbal medicine whitening and spot eliminating cream |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710631520.6A CN107375135A (en) | 2017-07-28 | 2017-07-28 | A kind of preparation method of Chinese herbal medicine whitening and spot eliminating cream |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107375135A true CN107375135A (en) | 2017-11-24 |
Family
ID=60341398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710631520.6A Withdrawn CN107375135A (en) | 2017-07-28 | 2017-07-28 | A kind of preparation method of Chinese herbal medicine whitening and spot eliminating cream |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107375135A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108309874A (en) * | 2018-05-07 | 2018-07-24 | 杨恒智 | Skin whitening, moisturizing face cream |
| CN108498433A (en) * | 2018-03-26 | 2018-09-07 | 刘莹艳 | A kind of cosmetics and preparation method thereof |
| CN111643407A (en) * | 2019-12-30 | 2020-09-11 | 沈定 | Facial mask composition containing Chinese herbal medicines, preparation method thereof and method for removing freckles and yellow spots on face |
| CN111686061A (en) * | 2020-07-31 | 2020-09-22 | 中科瑞晟芳香产业研究院(湖北)有限公司 | Composition with skin whitening and moisturizing effects and using method |
-
2017
- 2017-07-28 CN CN201710631520.6A patent/CN107375135A/en not_active Withdrawn
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108498433A (en) * | 2018-03-26 | 2018-09-07 | 刘莹艳 | A kind of cosmetics and preparation method thereof |
| CN108309874A (en) * | 2018-05-07 | 2018-07-24 | 杨恒智 | Skin whitening, moisturizing face cream |
| CN108309874B (en) * | 2018-05-07 | 2021-03-05 | 广州丽彦妆生物科技有限公司 | Whitening and moisturizing face cream |
| CN111643407A (en) * | 2019-12-30 | 2020-09-11 | 沈定 | Facial mask composition containing Chinese herbal medicines, preparation method thereof and method for removing freckles and yellow spots on face |
| CN111686061A (en) * | 2020-07-31 | 2020-09-22 | 中科瑞晟芳香产业研究院(湖北)有限公司 | Composition with skin whitening and moisturizing effects and using method |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104957298B (en) | Health jasmine tea | |
| CN107184495A (en) | A kind of preparation method of facial masks for whitening faces and removing spots | |
| CN107375135A (en) | A kind of preparation method of Chinese herbal medicine whitening and spot eliminating cream | |
| CN103053953A (en) | Functional bean sprouts prepared from Chinese herbal medicines used as both food and medicine and method for preparing functional bean sprouts | |
| CN102885186A (en) | Sea-buckthorn herbal tea and preparation technology thereof | |
| CN105997827A (en) | Compound camellia oil moisturizer and preparation method thereof | |
| CN107281041A (en) | A kind of preparation method of Chinese herbal medicine ferment facial mask | |
| CN107027915A (en) | A kind of Radix Mussaendae clearing away summerheat tea and preparation method thereof | |
| KR101053177B1 (en) | The healthy and funtional foods | |
| CN106754154A (en) | Mulberry health care wine and preparation method thereof | |
| CN106473995A (en) | The extracting method of Herba Bidentis Bipinnatae effective ingredient and its purposes preparing facial film | |
| CN106107100A (en) | Sheep body laying on meat feed additive and preparation method thereof | |
| CN106165750A (en) | A kind of preparation method of the sea-buckthorn tea that ferments | |
| CN105012769A (en) | Traditional Chinese medicine composition for treating diabetes and preparation method of traditional Chinese medicine composition | |
| CN109497388A (en) | A kind of prevention of cardiovascular and cerebrovascular disease and the drug of auxiliary | |
| CN108815015A (en) | A kind of eye mask and its production technology | |
| KR101206009B1 (en) | Method for producing composition for preventing hair loss or promoting hair generation | |
| CN108815391A (en) | A kind of preparation process of double Herba Dendrobii extracts of liver damage protection function | |
| CN103893381B (en) | Composition with lead-expelling function and its preparation method and application | |
| CN105925447B (en) | Compound health wine containing abelmoschus manihot and preparation method and application thereof | |
| CN111973667A (en) | Medicinal tea formula for reducing alpha-fetoprotein | |
| CN105995711A (en) | Fructus phyllanthi compound preparation and preparation method thereof | |
| CN105567515A (en) | Dried orange peel health-preserving yellow wine, and preparation method and application thereof | |
| CN104664195A (en) | Immunity-enhancing syrup and preparation method thereof | |
| CN108815082A (en) | A kind of facial mask and its production technology |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20171124 |
|
| WW01 | Invention patent application withdrawn after publication |