CN107361244A - It is a kind of to prevent scorching Chinese herbal feed additive of the bacillary gill of golden trout and application thereof - Google Patents
It is a kind of to prevent scorching Chinese herbal feed additive of the bacillary gill of golden trout and application thereof Download PDFInfo
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- CN107361244A CN107361244A CN201710596353.6A CN201710596353A CN107361244A CN 107361244 A CN107361244 A CN 107361244A CN 201710596353 A CN201710596353 A CN 201710596353A CN 107361244 A CN107361244 A CN 107361244A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
- Y02A40/818—Alternative feeds for fish, e.g. in aquacultures
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Abstract
Prevent scorching Chinese herbal feed additive of the bacillary gill of golden trout and application thereof the invention discloses a kind of, the composition and its parts by weight of additive are：15 22 parts of the fruit of Chinese magnoliavine, 18 23 parts of scouring rush, 18 24 parts of honeysuckle, 12 15 parts of the Radix Astragali, 12 17 parts of purple perilla, 13 17 parts of radix bupleuri, 58 parts of hairyvein agrimony, 8 12 parts of desmodium, 59 parts of Radix Isatidis.Have the beneficial effect that：The present invention is using Chinese herbal feed additive ingredient origin made from ultramicro grinding in the healthy and beneficial harmless natural plants of humans and animals, belong to renewable resource, it is good " green " medicated premix, there is clearing heat and detoxicating, sterilization antibacterial, the scorching purpose of the bacillary gill of prevention golden trout can be reached with the infringement of microorganism outside defense cell and its toxin to body；Ultramicro grinding can improve the bioavailability of medicine, reduce the dosage of Chinese medicine, improve drug effect.
Description
Technical field
The present invention relates to aquaculture feeds additive processing technique field, prevents the bacillary gill of golden trout more particularly to one kind
Scorching Chinese herbal feed additive and application thereof.
Background technology
Golden trout, salmon shape mesh salmonidae Pacific Ocean salmon category, belong to cold water fishes, meat flavour is delicious, nutritious, and the few meat of thorn is more, food
It is high with value, it is to integrate view and admire, swim fishing, the improved seeds of cuisines.A kind of fish occur in golden trout breeding process
Common disease --- the bacillary gill is scorching.Bacillary gill inflammation is one of alevin stage Major Diseases, body weight about 3g or so susceptible diseases.During morbidity
The bleeding of gill portion, mucus increase, gill filament swelling, and thalline covers the whole gill surface when serious, and cartilage is exposed, gill cover blank.Cause
This, it is necessary to a kind of feed addictive that can be improved lifting golden trout immunity, prevent bacillary gill inflammation is provided, so as to avoid
Due to economic loss caused by the scorching generation of the bacillary gill in golden trout breeding process.At present, it is also no both at home and abroad to disclose any pass
In with the relevant report for improving the scorching Chinese herbal feed additive of golden trout immunity, the bacillary gill of prevention and its application.
Chinese herbal medicine has increasingly been attracted attention as a kind of natural Substitutes For Antibiotic, and fish production practice is also demonstrate,proved
Bright, Chinese herbal medicine as mixed feeding agent or feed addictive while aquatic livestock production performance and feed efficiency is improved, fill by and can
The health of code insurance witness's body, have the double action of the property of medicine and trophism concurrently, be that traditional chemical synthesis feed addictive is not comparable
Intend, intensive, large-scale production the needs for the current culture fishery that is particularly suitable for use in.Therefore, antibiosis is substituted with Chinese herbal medicine
The additive of element will have been to be concerned by more and more people, and its application prospect also can be more extensive.But current Chinese medicine fodder addition
The research level of agent is relatively low, and manufacture craft simple coarse, the technological element of a product is relatively low, and quality is not sufficiently stable, such problem
The serious popularization and application that govern Chinese medicine fodder addition.
Prior art such as Authorization Notice No. is the B of CN 101828643 Chinese invention patent, discloses raising lefteye flounder and is immunized
The Chinese herbal feed additive of power, the weight ratio of each component are the Radix Astragali 50, the bighead atractylodes rhizome 15, the windproof 15, tuber of stemona 15, hairyvein agrimony 30, soil
Poria cocos 30.The additive cost is cheap, addition is small, Chinese herbal feed additive easy to use, can improving immunity of paralichthys olivaceus,
But the feed addictive simply carries out raw material simple mixing and crushing, fails the active ingredient of each raw material to discharge
Come, the drug effect unobvious for improving immunity, also there is certain room for promotion in terms of the effect of fish immunity power is improved.
The content of the invention
It is extensive, green, environmentally friendly it is an object of the invention to provide a kind of raw material sources, the bacillary gill of golden trout can be prevented
Inflammation, improves absorbing for golden trout, effect of drugs significantly prevent the scorching Chinese herbal feed additive of the bacillary gill of golden trout and its
Purposes.
The present invention is directed to the problem of being mentioned in above-mentioned technology, and the technical scheme taken is：One kind prevention bacillary gill of golden trout
Scorching Chinese herbal feed additive, composition and its parts by weight are：Fruit of Chinese magnoliavine 15-22 parts, scouring rush 18-23 parts, honeysuckle 18-24
Part, Radix Astragali 12-15 parts, purple perilla 12-17 parts, radix bupleuri 13-17 parts, hairyvein agrimony 5-8 parts, desmodium 8-12 parts, Radix Isatidis 5-9 parts.
Above-mentioned additive component derives from harmless natural plants healthy and beneficial to humans and animals, belongs to renewable resource, is good
" green " medicated premix, there is clearing heat and detoxicating, sterilization antibacterial, can be with microorganism outside defense cell and its toxin to machine
The infringement of body, reach the scorching purpose of the bacillary gill of prevention golden trout, and the immunity of golden trout can be improved, and promote antibody tormation.
A kind of preparation method for preventing the scorching Chinese herbal feed additive of the bacillary gill of golden trout, including raw material prepares, first powder
Broken and ultramicro grinding, preparation method specifically include following steps：
Raw material prepares：The fruit of Chinese magnoliavine, scouring rush, honeysuckle, the Radix Astragali, purple perilla, radix bupleuri, hairyvein agrimony, desmodium, Radix Isatidis are existed respectively
40-50 DEG C of dry 6-8h, standby, the step uses the continuous drying technique of low temperature, can reduce waving for active ingredient in Chinese herbal medicine
Hair rate, loss is reduced, improve the drug effect content of Chinese herb feed additive；
Just crush：Herbal raw material obtains coarse granule through pulverizer preliminary crushing to 20-50 mesh respectively, standby, by just crushing energy
The raw material of certain fineness is enough provided for ultramicro grinding, makes ultramicro grinding be more prone to carry out, improves the operating efficiency of ultramicro grinding,
The dosage of auxiliary agent is reduced, saves energy consumption and cost；
Ultramicro grinding：Each raw material coarse granule is measured by formula, is well mixed, by Chinese herbal medicine coarse granule using weight ratio as 1:1.5-2
Ratio add auxiliary agent, 40-50min is crushed in micronizer, control and crushes temperature as 20-30 DEG C, be spray-dried and produce
To the superfines that average grain diameter is 6-10 μm, as Chinese herbal feed additive, standby, ultramicro grinding can be broken in the step
Bad Chinese herbal medicine cell membrane, cell-wall breaking ratio are not less than 95%, intracellular effective drug ingedient is fully exposed, improve
The bioavailability of medicine, the dosage for reducing Chinese medicine, medium-height grass the effective elements of the medicine can be released effectively rapidly in golden trout enteron aisle
To put, golden trout intestines and stomach can be absorbed effectively, improve drug effect, and improve the uniformity of particle to a certain extent,
Chinese herbal feed additive is set to be easier to be dispersed in feed.
Preferably, auxiliary agent is the mixture of decentralized medium and active peptides in ultramicro grinding, and its ratio is 1:0.00002-
0.00003, decentralized medium is water or ethanol or isopropanol or glycerine or polyethylene glycol, the amino acid sequence of active peptides are
HSHACACRCLRCRVLHPGCVNCYRCSR, the active peptides may act on the coarse grained cell membrane of Chinese herbal medicine, formed on film
The ion channel of cross-film, the integrality of cell membrane is destroyed, come out intracellular active drug composition quick release, carry significantly
Superb fine sporoderm-broken rate, and the activity of active ingredient is not influenceed；It is coarse grained that the addition of the auxiliary agent can improve Chinese herbal medicine
Dispersiveness, the mobility of material is improved, avoid the generation of agglomeration, improve the operating efficiency and ultramicro grinding of ultramicro grinding
Effect, while the sporoderm-broken rate of ultramicro grinding can be improved, the drug effect and utilization rate of Chinese herbal medicine are improved, reduces addition, saves raising
Cost.
A kind of purposes for preventing the scorching Chinese herbal feed additive of the bacillary gill of golden trout：Chinese herbal feed is added in feed
Fed, addition is the 0.2-0.3% of golden trout feed relative, on the one hand the feed has the work of clearing heat and detoxicating sterilization antibacterial
With, it can eliminate, into the pathogen in golden trout body and parasite, to reach and prevent the scorching purpose of the bacillary gill, on the other hand addition
The addition of agent can be effectively facilitated digestibility and utilization of the feed nutrition material in golden trout enteron aisle, improve the immunocompetence of golden trout itself
And resistance against diseases, improve the cultivation survival rate of golden trout.
Compared with prior art, the advantage of the invention is that：
1. the ingredient origin of the Chinese herbal feed additive of the present invention is in the healthy and beneficial harmless natural plants of humans and animals, category
It is good " green " medicated premix in renewable resource, there is clearing heat and detoxicating, sterilization antibacterial, can defend thin
The infringement of extracellular microorganism and its toxin to body, reach the scorching purpose of the bacillary gill of prevention golden trout, and exempting from for golden trout can be improved
Epidemic disease power, and promote antibody tormation.
2. the present invention can destroy Chinese herbal medicine cell membrane using ultramicro grinding, make intracellular effective drug ingedient fully sudden and violent
Expose, improve the bioavailability of medicine, reduce the dosage of Chinese medicine, improve drug effect, and improve to a certain extent
The uniformity of particle, Chinese herbal feed additive is set to be easier to be dispersed in feed.
3. Chinese herbal feed additive of the present invention is added in feed so that feed, which has, prevents the scorching work of the bacillary gill
With, and digestibility and utilization of the feed nutrition material in golden trout enteron aisle can be effectively facilitated, improve golden trout itself immunocompetence and
Resistance against diseases, improve the cultivation survival rate of golden trout.
Specific embodiment
The present invention program is described further below by embodiment：
Embodiment 1：
A kind of to prevent the scorching Chinese herbal feed additive of the bacillary gill of golden trout, composition and its parts by weight are：19 parts of the fruit of Chinese magnoliavine, scouring rush
21 parts, 21 parts of honeysuckle, 14 parts of the Radix Astragali, 15 parts of purple perilla, 15 parts of radix bupleuri, 6 parts of hairyvein agrimony, 10 parts of desmodium, 7 parts of Radix Isatidis.
A kind of preparation method for preventing the scorching Chinese herbal feed additive of the bacillary gill of golden trout, including raw material prepares, first powder
Broken and ultramicro grinding, preparation method specifically include following steps：
1）Raw material prepares：The fruit of Chinese magnoliavine, scouring rush, honeysuckle, the Radix Astragali, purple perilla, radix bupleuri, hairyvein agrimony, desmodium, Radix Isatidis are existed respectively
45 DEG C of dry 7h, standby, the step uses the continuous drying technique of low temperature, can reduce the volatility of active ingredient in Chinese herbal medicine,
Loss is reduced, improves the drug effect content of Chinese herb feed additive；
2）Just crush：By herbal raw material respectively through pulverizer preliminary crushing, cross 40 mesh and obtain coarse granule, it is standby, by just crushing
The raw material of certain fineness can be provided for ultramicro grinding, make ultramicro grinding be more prone to carry out, improve the work effect of ultramicro grinding
Rate, the dosage of auxiliary agent is reduced, save energy consumption and cost；
3）Ultramicro grinding：Each raw material coarse granule is measured by formula, is well mixed, by Chinese herbal medicine coarse granule using weight ratio as 1:1.8
Ratio add auxiliary agent, 42min is crushed in micronizer, control crush temperature be 20-30 DEG C, spray drying be put down
The superfines that equal particle diameter is 6-10 μm, as Chinese herbal feed additive, it is standby, during ultramicro grinding can be destroyed in the step
Herbal medicine cell membrane, cell-wall breaking ratio are not less than 95%, intracellular effective drug ingedient is fully exposed, improve medicine
Bioavailability, reduce the dosage of Chinese medicine, medium-height grass the effective elements of the medicine can effectively discharge rapidly in golden trout enteron aisle, gold
Trout intestines and stomach can be absorbed effectively, improve drug effect, and improve the uniformity of particle to a certain extent, make medium-height grass
Medicine feed addictive is easier to be dispersed in feed.
Auxiliary agent is the mixture of decentralized medium and active peptides in above-mentioned ultramicro grinding, and its ratio is 1:0.000025, point
Dispersion media is polyethylene glycol, and the amino acid sequences of active peptides is HSHACACRCLRCRVLHPGCVNCYRCSR, the active peptides
The coarse grained cell membrane of Chinese herbal medicine is may act on, the ion channel of cross-film is formed on film, the integrality of cell membrane is destroyed, makes
Intracellular active drug composition quick release comes out, and greatly improves the sporoderm-broken rate of ultramicro grinding, and do not influence active ingredient
Activity；The addition of the auxiliary agent can improve the coarse grained dispersiveness of Chinese herbal medicine, improve the mobility of material, avoid agglomeration
Occur, improve the operating efficiency of ultramicro grinding and the effect of ultramicro grinding, while the sporoderm-broken rate of ultramicro grinding can be improved, in raising
The drug effect and utilization rate of herbal medicine, addition is reduced, save feeding cost.
A kind of purposes for preventing the scorching Chinese herbal feed additive of the bacillary gill of golden trout：Chinese herbal feed is added in feed
Being fed, addition is the 0.25% of golden trout feed relative, on the one hand the feed has the function that clearing heat and detoxicating, sterilization antibacterial,
It can eliminate, into the pathogen in golden trout body and parasite, to reach and prevent the scorching purpose of the bacillary gill, another aspect additive
Addition can be effectively facilitated digestibility and utilization of the feed nutrition material in golden trout enteron aisle, improve golden trout itself immunocompetence and
Resistance against diseases, improve the cultivation survival rate of golden trout.
Embodiment 2：
A kind of to prevent the scorching Chinese herbal feed additive of the bacillary gill of golden trout, composition and its parts by weight are：20 parts of the fruit of Chinese magnoliavine, scouring rush
21 parts, 23 parts of honeysuckle, 14 parts of the Radix Astragali, 14 parts of purple perilla, 16 parts of radix bupleuri, 6 parts of hairyvein agrimony, 8 parts of desmodium, 7 parts of Radix Isatidis.
A kind of preparation method for preventing the scorching Chinese herbal feed additive of the bacillary gill of golden trout, specifically includes following steps：
1）By the fruit of Chinese magnoliavine, scouring rush, honeysuckle, the Radix Astragali, purple perilla, radix bupleuri, hairyvein agrimony, desmodium, Radix Isatidis respectively in 50 DEG C of dryings
6h, standby, the step uses the continuous drying technique of low temperature, can reduce the volatility of active ingredient in Chinese herbal medicine, reduces loss,
Improve the drug effect content of Chinese herb feed additive；
2）Herbal raw material is crushed to 50 mesh through pulverizer and obtains Chinese herbal medicine coarse granule, it is standby, can be ultra micro by just crushing
The raw material that certain fineness is provided is crushed, makes ultramicro grinding be more prone to carry out, improves the operating efficiency of ultramicro grinding, reduces auxiliary agent
Dosage, save energy consumption and cost；
3）Each raw material coarse granule is measured by formula, is well mixed, by Chinese herbal medicine coarse granule using weight ratio as 1:2 ratio adds
Auxiliary agent, auxiliary agent are the mixture of ethanol and active peptides, and its ratio is 1:0.00003,40min is crushed in micronizer,
It is 20-30 DEG C to control and crush temperature, and spray drying obtains the superfines that average grain diameter is 6-10 μm, as Chinese herbal feed
Additive, standby, ultramicro grinding can destroy Chinese herbal medicine cell membrane in the step, and cell-wall breaking ratio is not less than 95%, make intracellular
Effective drug ingedient is fully exposed, and improves the bioavailability of medicine, reduces the dosage of Chinese medicine, Chinese herbal medicine it is effective
Composition can effectively be discharged rapidly in golden trout enteron aisle, and golden trout intestines and stomach can be absorbed effectively, improve drug effect, and
The uniformity of particle is improved to a certain extent, makes Chinese herbal feed additive be easier to be dispersed in feed.
A kind of purposes for preventing the scorching Chinese herbal feed additive of the bacillary gill of golden trout：Chinese herbal feed is added in feed
Being fed, addition is the 0.22% of golden trout feed relative, on the one hand the feed has the function that clearing heat and detoxicating, sterilization antibacterial,
It can eliminate, into the pathogen in golden trout body and parasite, to reach and prevent the scorching purpose of the bacillary gill, another aspect additive
Addition can be effectively facilitated digestibility and utilization of the feed nutrition material in golden trout enteron aisle, improve golden trout itself immunocompetence and
Resistance against diseases, improve the cultivation survival rate of golden trout.
Embodiment 3：
A kind of to prevent the scorching Chinese herbal feed additive of the bacillary gill of golden trout, composition and its parts by weight are：19 parts of the fruit of Chinese magnoliavine, scouring rush
22 parts, 23 parts of honeysuckle, 14 parts of the Radix Astragali, 17 parts of purple perilla, 13 parts of radix bupleuri, 7 parts of hairyvein agrimony, 11 parts of desmodium, 9 parts of Radix Isatidis.
A kind of preparation method for preventing the scorching Chinese herbal feed additive of the bacillary gill of golden trout, is concretely comprised the following steps：To respectively it match somebody with somebody
Material, in 40 DEG C of dry 8h, then crushes through pulverizer, obtains the Chinese herbal medicine coarse granule of 30 mesh；Each raw material coarse granule is measured by formula,
It is well mixed, by Chinese herbal medicine coarse granule using weight ratio as 1:2 ratio adds the mixture of water and active peptides, and water and activity are more
The ratio of peptide is 1:0.00002,40min is crushed in micronizer, it is 20-30 DEG C to control and crush temperature, and spray drying is
Obtain the superfines that average grain diameter is 6-10 μm, as Chinese herbal feed additive.
A kind of purposes for preventing the scorching Chinese herbal feed additive of the bacillary gill of golden trout：Chinese herbal feed is added in feed
Fed, addition is the 0.3% of golden trout feed relative.
Routine operation in the operating procedure of the present invention is well known to those skilled in the art, herein without repeating.
Technical scheme is described in detail embodiment described above, it should be understood that it is described above only
For the specific embodiment of the present invention, it is not intended to limit the invention, all any modifications made in the spirit of the present invention,
Supplement or similar fashion replacement etc., should be included in the scope of the protection.
SEQUENCE LISTING
<110>Tonghua Teachers College
<120>It is a kind of to prevent scorching Chinese herbal feed additive of the bacillary gill of golden trout and application thereof
<130> 1
<160> 1
<170> PatentIn version 3.5
<210> 1
<211> 27
<212> PRT
<213>It is artificial synthesized
<400> 1
His Ser His Ala Cys Ala Cys Arg Cys Leu Arg Cys Arg Val Leu His
1 5 10 15
Pro Gly Cys Val Asn Cys Tyr Arg Cys Ser Arg
20 25
Claims (10)
1. a kind of prevent the scorching Chinese herbal feed additive of the bacillary gill of golden trout, it is characterised in that：The composition of described additive
And its parts by weight are：Fruit of Chinese magnoliavine 15-22 parts, scouring rush 18-23 parts, honeysuckle 18-24 parts, Radix Astragali 12-15 parts, purple perilla 12-17 parts,
Radix bupleuri 13-17 parts, hairyvein agrimony 5-8 parts, desmodium 8-12 parts, Radix Isatidis 5-9 parts.
A kind of 2. Chinese herbal feed additive for preventing the bacillary gill inflammation of golden trout according to claim 1, it is characterised in that：
The preparation method of described additive includes raw material preparation, just crushing and ultramicro grinding.
3. a kind of preparation method for preventing the scorching Chinese herbal feed additive of the bacillary gill of golden trout according to claim 2,
It is characterized in that：Auxiliary agent is the mixture of decentralized medium and active peptides in ultramicro grinding in described ultramicro grinding, its ratio
For 1:0.00002-0.00003.
4. a kind of preparation method for preventing the scorching Chinese herbal feed additive of the bacillary gill of golden trout according to claim 3,
It is characterized in that：Decentralized medium is water or ethanol or isopropanol or glycerine or polyethylene glycol in described ultramicro grinding.
5. a kind of preparation method for preventing the scorching Chinese herbal feed additive of the bacillary gill of golden trout according to claim 3,
It is characterized in that：The amino acid sequence of active peptides is HSHACACRCLRCRVLHPGCVNCYRCSR in described ultramicro grinding.
6. a kind of preparation method for preventing the scorching Chinese herbal feed additive of the bacillary gill of golden trout according to claim 2,
It is characterized in that：The weight of Chinese herbal medicine coarse granule and auxiliary agent ratio is 1 in described ultramicro grinding:1.5-2.
7. a kind of preparation method for preventing the scorching Chinese herbal feed additive of the bacillary gill of golden trout according to claim 2,
It is characterized in that：40-50min is crushed in described ultramicro grinding, it is 20-30 DEG C to crush temperature.
8. a kind of preparation method for preventing the scorching Chinese herbal feed additive of the bacillary gill of golden trout according to claim 2,
It is characterized in that：The average grain diameter of superfines is 6-10 μm in described ultramicro grinding.
9. a kind of preparation method for preventing the scorching Chinese herbal feed additive of the bacillary gill of golden trout according to claim 2,
It is characterized in that：The temperature of low temperature drying is 40-50 DEG C during described raw material prepares, time 6-8h.
A kind of 10. purposes for preventing the scorching Chinese herbal feed additive of the bacillary gill of golden trout, it is characterised in that：Described Chinese herbal medicine
Feed addition is fed in feed, and addition is the 0.2-0.3% of golden trout feed relative.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113133507A (en) * | 2020-01-19 | 2021-07-20 | 安琪酵母股份有限公司 | Compound animal protection product for preventing and treating black gill disease of crucian carp and preparation and application thereof |
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|---|---|---|---|---|
| CN101152391A (en) * | 2007-09-30 | 2008-04-02 | 北京凯瑞创新医药科技有限公司 | Pharmaceutical formulations for treating traumatic injury, preparing method and quality control method thereof |
| CN101185658A (en) * | 2007-09-30 | 2008-05-28 | 北京凯瑞创新医药科技有限公司 | Intermediate compound of a liquid state traditional Chinese medicinal preparation and preparation method and application thereof |
| CN104435596A (en) * | 2014-11-06 | 2015-03-25 | 占水秀 | Oral administration medicine for treating parotitis of soft-shelled turtles |
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2017
- 2017-07-20 CN CN201710596353.6A patent/CN107361244A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101152391A (en) * | 2007-09-30 | 2008-04-02 | 北京凯瑞创新医药科技有限公司 | Pharmaceutical formulations for treating traumatic injury, preparing method and quality control method thereof |
| CN101185658A (en) * | 2007-09-30 | 2008-05-28 | 北京凯瑞创新医药科技有限公司 | Intermediate compound of a liquid state traditional Chinese medicinal preparation and preparation method and application thereof |
| CN104435596A (en) * | 2014-11-06 | 2015-03-25 | 占水秀 | Oral administration medicine for treating parotitis of soft-shelled turtles |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113133507A (en) * | 2020-01-19 | 2021-07-20 | 安琪酵母股份有限公司 | Compound animal protection product for preventing and treating black gill disease of crucian carp and preparation and application thereof |
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