CN107348483A - A kind of pregnant and lying-in women's full function nutritious supplementary pharmaceutical - Google Patents
A kind of pregnant and lying-in women's full function nutritious supplementary pharmaceutical Download PDFInfo
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- CN107348483A CN107348483A CN201710543693.2A CN201710543693A CN107348483A CN 107348483 A CN107348483 A CN 107348483A CN 201710543693 A CN201710543693 A CN 201710543693A CN 107348483 A CN107348483 A CN 107348483A
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- Prior art keywords
- pregnant
- women
- lying
- vitamin
- nutritious supplementary
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- 235000008935 nutritious Nutrition 0.000 title claims abstract description 44
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims abstract description 38
- 239000000843 powder Substances 0.000 claims abstract description 35
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims abstract description 32
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims abstract description 31
- 235000016709 nutrition Nutrition 0.000 claims abstract description 27
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims abstract description 24
- 239000011575 calcium Substances 0.000 claims abstract description 24
- 229910052791 calcium Inorganic materials 0.000 claims abstract description 24
- 235000001465 calcium Nutrition 0.000 claims abstract description 24
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims abstract description 23
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 21
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 20
- DLRVVLDZNNYCBX-UHFFFAOYSA-N Polydextrose Polymers OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(O)O1 DLRVVLDZNNYCBX-UHFFFAOYSA-N 0.000 claims abstract description 20
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims abstract description 19
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- RMRCNWBMXRMIRW-BYFNXCQMSA-M cyanocobalamin Chemical compound N#C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O RMRCNWBMXRMIRW-BYFNXCQMSA-M 0.000 claims abstract description 18
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims abstract description 16
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- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims abstract description 14
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- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims abstract description 12
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- WIGIZIANZCJQQY-UHFFFAOYSA-N 4-ethyl-3-methyl-N-[2-[4-[[[(4-methylcyclohexyl)amino]-oxomethyl]sulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide Chemical compound O=C1C(CC)=C(C)CN1C(=O)NCCC1=CC=C(S(=O)(=O)NC(=O)NC2CCC(C)CC2)C=C1 WIGIZIANZCJQQY-UHFFFAOYSA-N 0.000 claims abstract description 10
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- 235000013336 milk Nutrition 0.000 claims abstract description 10
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- 210000004080 milk Anatomy 0.000 claims abstract description 10
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- 235000013856 polydextrose Nutrition 0.000 claims abstract description 10
- 235000020183 skimmed milk Nutrition 0.000 claims abstract description 10
- WHMDKBIGKVEYHS-IYEMJOQQSA-L Zinc gluconate Chemical compound [Zn+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O WHMDKBIGKVEYHS-IYEMJOQQSA-L 0.000 claims abstract description 9
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- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims abstract description 9
- PPASLZSBLFJQEF-RXSVEWSESA-M sodium-L-ascorbate Chemical compound [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RXSVEWSESA-M 0.000 claims abstract description 9
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- JVXHQHGWBAHSSF-UHFFFAOYSA-L 2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate;hydron;iron(2+) Chemical compound [H+].[H+].[Fe+2].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O JVXHQHGWBAHSSF-UHFFFAOYSA-L 0.000 claims description 6
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims description 6
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- 239000004615 ingredient Substances 0.000 claims description 6
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- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A23L33/155—Vitamins A or D
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The present invention relates to medicine and nutritional supplement arts, more particularly to a kind of pregnant and lying-in women's full function nutritious supplementary pharmaceutical.Pregnant and lying-in women's full function nutritious supplementary pharmaceutical of the present invention is by polydextrose, skimmed milk powder, whole-fat milk powder, lactalbumin, galactooligosaccharide, FOS, oligoisomaltose, lactose, yam flour, jujube powder, DHA algal oil, corn syrup solid, sodium ascorbate, casein sodium, sodium citrate, phosphatide, L ascorbic acid, bata-carotene, nicotinic acid, riboflavin, axerophtholum aceticum, D calcium pantothenates, folic acid, tocopherol, puridoxine hydrochloride, thiamine hydrochloride, cyanocobalamin, vitamine D3, taurine, newborn mineral salt, magnesium sulfate, zinc gluconate, made of sodium iron ethylene diamine tetra acetate and CPP, it is preferred that electuary and chewable tablet.Nutritional supplementation agent prescription of the present invention is reasonable, effect is comprehensive, edible safety, and through experiment, science takes nutritious supplementary pharmaceutical of the present invention and is remarkably improved pregnant and lying-in women's immunity.
Description
Technical field
The present invention relates to medicine and nutritional supplement arts, more particularly to a kind of pregnant and lying-in women's full function nutritious supplementary pharmaceutical.
Background technology
Nutritious supplementary pharmaceutical, also known as dietary supplements, refer to the amino for containing some specific nutritions element, supplementing needed by human body
The nutritional agents of acid, trace element, vitamin, mineral matter etc..A kind of supplementary means of the nutritious supplementary pharmaceutical as diet, makes up
Possible insufficiency of intake in mankind's normal meals, while be nutrient necessary to human body again, and finally realize regulation human normal
The purpose of physiological activity.
All ages and classes, sex, the crowd of body condition are due to the difference of its physiological condition, the species sum of required nutrient
Amount is often obvious different, and therefore, the nutritious supplementary pharmaceutical of special formulation composition is developed for specific crowd turns into medicine food row
The widespread consensus of industry.
At present, researcher have developed some nutritional supplement products specifically for pregnant and lying-in women.For example, patent Shen
A kind of maternal nutritional reinforcing please be disclosed in CN2015102135883 " a kind of maternal nutritional fortified compositions and preparation method thereof "
Composition, by yeast beta-dextran, ferric pyrophosphate, tricalcium phosphate, inulin, trehalose, WPC, red date powder and soybean
Separated protein powder is made.Patent application CN2015106186649 " a kind of maternal nutritional premix and includes maternal nutritional premix
Food " in disclose a kind of maternal nutritional premix, including following nutrient:Vitamin A, vitamin D, vitamin E, dimension life
Plain K, vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin C, nicotinic acid etc..Patent of invention
Disclosed in CN2012105859417 " be used for strengthen maternal nutritional and the preparation of brain health care of children " it is a kind of be used for maternal nutritional and
The preparation of brain health care of children, it is made by marine alga DHA, taurine, soybean lecithin and lactalbumin.Patent application
CN201110460853X discloses a kind of addition DHA and is adapted in " a kind of addition DHA is adapted to the red jujube thick syrup that pregnant woman wet nurse eats "
The red jujube thick syrup that pregnant woman wet nurse eats, by DHA, AA, phytosterol, oligoisomaltose, phosphatide, vitamin A, vitamin B3,
Vitamin C, vitamine D3, folic acid, taurine, calcium, iron, zinc etc. are made.
The present invention, by proportioning test repeatedly, further optimizes pregnant and lying-in women's nutrition benefit on the basis of the said goods
The formula composition and component content proportioning of agent are filled, a kind of full function nutrition for being extremely suitable for pregnant and lying-in women and eating finally has been made
Replenishers, nutritional supplementation agent prescription of the present invention rationally, effect comprehensively, edible safety, science, which is taken, to be remarkably improved pregnant and lying-in women and exempts from
Epidemic disease power, auxiliary fetal brain and body development, prevention pregnant and lying-in women and fetus anaemia.
The content of the invention
The invention provides a kind of pregnant and lying-in women's full function nutritious supplementary pharmaceutical, it is characterised in that it is by following weight parts
Made of raw material:
Polydextrose 12-30;Skimmed milk powder 3.9-5.4;Whole-fat milk powder 6.4-6.7;Lactalbumin 3.2-3.5;Oligomeric half
Lactose 4.1-5.2;FOS 4.65-5.80;Oligoisomaltose 3.03-3.25;Lactose 7.2-7.5;Yam flour 3.6-
4.0;Jujube powder 3.0-3.2;DHA algal oil 1.65-1.72;Corn syrup solid 20-28;Sodium ascorbate 0.037-0.049;Junket
Protein acid sodium 0.65-0.82;Sodium citrate 0.93-1.49;Phosphatidase 2 .52-2.70;L-AA 0.16-0.20;β-carrot
Plain 0.85-1.45;Nicotinic acid 0.005-0.035;Riboflavin 0.001-0.006;Axerophtholum aceticum 0.0009-0.0042;D-VB5
Calcium 0.002-0.075;Folic acid 0.0002-0.0009;Tocopherol 0.009-0.024;Puridoxine hydrochloride 0.001-0.006;Hydrochloric acid
Thiamine 0.001-0.006;Cyanocobalamin 0.000001-0.000012;Vitamine D3 0.000001-0.000013;Taurine
0.08-0.15;Newborn mineral salt 1.6-2.7;Magnesium sulfate 0.26-0.70;Zinc gluconate 0.052-0.126;Ethylenediamine tetra-acetic acid
Ferrisodium 0.105-0.625;CPP 0.23-0.26.
The parts by weight of above-mentioned raw materials are preferred:
Polydextrose 20;Skimmed milk powder 4.4;Whole-fat milk powder 6.5;Lactalbumin 3.3;Galactooligosaccharide 4.5;FOS
4.95;Oligoisomaltose 3.15;Lactose 7.3;Yam flour 3.8;Jujube powder 3.2;DHA algal oil 1.69;Corn syrup solid 24;
Sodium ascorbate 0.039;Casein sodium 0.72;Sodium citrate 1.21;Phosphatidase 2 .60;L-AA 0.18;Beta carotene
1.05;Nicotinic acid 0.015;Riboflavin 0.002;Axerophtholum aceticum 0.0022;D-VB5 calcium 0.015;Folic acid 0.0004;Tocopherol
0.012;Puridoxine hydrochloride 0.002;Thiamine hydrochloride 0.003;Cyanocobalamin 0.000003;Vitamine D3 0.000003;Taurine
0.12;Newborn mineral salt 1.9;Magnesium sulfate 0.46;Zinc gluconate 0.082;Sodium iron ethylene diamine tetra acetate 0.175;Casein phosphoric acid
Peptide 0.24.
Further, the nutritional ingredient of following weight is contained per 100g pregnant and lying-in women's full function nutritious supplementary pharmaceuticals of the present invention:
Protein 9.5-10.2g;Fatty 5.2-5.4g;Carbohydrate 50.5-53.0g;Dietary fiber 22.5-24.0g;
Sodium 108-112mg;Vitamin A 1350-1365 μ g;Vitamin D 1.8-2.0 μ g;Vitamin E 14.85-15.05mg;Dimension life
Plain B1 1.65-1.72mg;Vitamin B2 1.66-1.70mg;Vitamin B6 1.66-1.70mg;Vitamin B12 4.64-
4.70μg;Vitamin C 185.0-185.6mg;Nicotinic acid 20.60-20.75mg;Folic acid 368-378 μ g;Pantothenic acid 5.45-5.55mg;
Magnesium 136-141mg;Calcium 990-1020mg;Iron 18.4-18.7mg;Zinc 13.79-13.82mg;Taurine 119-123mg.
Preferably, the nutritional ingredient containing following weight in every 100g pregnant and lying-in women's full function nutritious supplementary pharmaceuticals of the present invention:
Protein 9.8g;Fatty 5.3g;Carbohydrate 52.0g;Dietary fiber 23.5g;Sodium 110mg;Vitamin A
1360μg;The μ g of vitamin D 1.9;Vitamin E 15.00mg;Vitamin B1 1.68mg;Vitamin B2 1.68mg;Vitamin B6
1.68mg;The μ g of vitamin B12 4.67;Vitamin C 185.4mg;Nicotinic acid 20.70mg;The μ g of folic acid 376;Pantothenic acid 5.49mg;Magnesium
140mg;Calcium 1000mg;Iron 18.6mg;Zinc 13.80mg;Taurine 120mg.
We have discovered that there is mutually interdependent during absorbing and acting on performance between different classes of nutrient
Deposit, condition each other, synergistic relation.If carrying out the nutritional supplementation of single kind, internal nutrition on the one hand can be destroyed
Environment, cause nutrient imbalance, on the other hand, its absorption also tends to unsatisfactory with action effect.Such as:
(1) according to investigations, having quite a few in the pregnant and lying-in women and children of China's hypoferric anemia is replenished the calcium caused by excess,
Reason is that calcium belongs to divalent ion together with iron, and excessive calcium can hinder the absorption of iron.Therefore our formula adds while replenishing the calcium
The iron of specified quantitative is added, it is offset inhibition caused by the absorption of normal ferro element of verifying of replenishing the calcium just.
(2) there is no vitamin D cooperation in calcium supplementing product, effect of supplemented calcium is poor.
(3) single benefit iron, without ascorbic participation, the assimilation effect of iron is very undesirable.
(4) DHA is used merely, cerebrum tonifying effect is very limited.Itself and lecithin, taurine are used cooperatively by we, make it
The effect of brain development is promoted to be remarkably reinforced.
Further, the raw material of pregnant and lying-in women's full function nutritious supplementary pharmaceutical of the present invention, which is made, also includes following weight parts:
Garlic P.E 1.05-1.20.
Preferably, the garlic P.E is made by following methods:Fresh garlic is taken to be squeezed the juice after removing the peel, gained squeezeding juice
Ultrafiltration is carried out using the milipore filter that molecular weight is 500-600 that dams through centrifuged supernatant, after gained filtrate is freeze-dried i.e.
Obtain garlic P.E.
It is well known that garlic P.E has the function that strengthen immunity, but the garlic extraction prepared using conventional method
Thing can produce certain stimulation to pregnant and lying-in women's intestines and stomach, therefore excessive from being not added with conventional pregnant and lying-in women's nutritious supplementary pharmaceutical
Garlic extract, through experiment, it has been found that it is immune that garlic juice freeze-dried powder made from adding freeze-drying is remarkably improved product enhancing
The effect of power, and the adverse reaction in any stimulating gastrointestinal road will not be produced.
As a preferred embodiment, pregnant and lying-in women's full function nutritious supplementary pharmaceutical of the present invention is made up of the raw material of following weight parts
's:
Polydextrose 20;Skimmed milk powder 4.4;Whole-fat milk powder 6.5;Lactalbumin 3.3;Galactooligosaccharide 4.5;FOS
4.95;Oligoisomaltose 3.15;Lactose 7.3;Yam flour 3.8;Jujube powder 3.2;DHA algal oil 1.69;Corn syrup solid 24;
Sodium ascorbate 0.039;Casein sodium 0.72;Sodium citrate 1.21;Phosphatidase 2 .60;L-AA 0.18;Beta carotene
1.05;Nicotinic acid 0.015;Riboflavin 0.002;Axerophtholum aceticum 0.0022;D-VB5 calcium 0.015;Folic acid 0.0004;Tocopherol
0.012;Puridoxine hydrochloride 0.002;Thiamine hydrochloride 0.003;Cyanocobalamin 0.000003;Vitamine D3 0.000003;Taurine
0.12;Newborn mineral salt 1.9;Magnesium sulfate 0.46;Zinc gluconate 0.082;Sodium iron ethylene diamine tetra acetate 0.175;Casein phosphoric acid
Peptide 0.24;Garlic P.E 1.15.
Further, pregnant and lying-in women's full function nutritious supplementary pharmaceutical is prepared into electuary or chewable tablets by this area routine
The method of agent, pregnant and lying-in women's full function nutritious supplementary pharmaceutical electuary or chewable tablet of the present invention is made.
A kind of moreover, it relates to pregnant and lying-in women's full function nutritious supplementary pharmaceutical answering in pregnant and lying-in women's food is prepared
With.
A kind of moreover, it relates to pregnant and lying-in women's full function nutritious supplementary pharmaceutical answering in health care for pregnant and puerperal women product are prepared
With.
To sum up, pregnant and lying-in women's full function nutritious supplementary pharmaceutical of the present invention has following features:
(1) nutritional ingredient most easily lacked comprising pregnant and lying-in women and wet nurse:Calcium, magnesium, zinc, vitamin E, vitamin B1, dimension life
Plain B2, vitamin B6, nicotinic acid, pantothenic acid, vitamin C etc.;
(2) nutritional ingredient additionally supplemented especially is needed comprising pregnant and lying-in women and wet nurse:It is crystal diabetin, lactalbumin, full-cream
Milk powder, skimmed milk powder, oligoisomaltose, polydextrose, galactooligosaccharide, jujube powder, phosphatide, yam flour, beta carotene,
Taurine, CPP etc.;
(3) DHA, phosphatide, taurine are used in combination according to a certain ratio, hence it is evident that improve the effect for promoting fetal brain development
Fruit, the brain development of people completes more than 30% in foetal period, therefore foetal period cerebrum tonifying is just particularly important;
(4) vitamin B is the indispensable micronutrient of body metabolism, but its ratio was not at that time, and absorptivity is very poor, this
B1, B2, B6 use special ratios in invention formula, improve assimilation effect;
(5) pregnant woman anemia is prevented, the incidence of anaemia is very high in China pregnant and lying-in women, and anaemia is strong to pregnant and lying-in women itself
Health, serious harm can all be produced to development of fetus, in order to effectively prevent pregnant woman anemia, we used in formula three groups it is pre-
The prescription of anti-anaemia:1. iron+VC prevents hypoferric anemia;2. folic acid+B12 prevents megaloblastic anemia;3. jujube+Chinese yam carries
Take thing, rich in nutrition;
(6) barrier action of placenta is strengthened, placenta is the nutrition storehouse of fetus, excretion channel, and bacterial virus is completely cut off
Barrier, healthy placenta is most important to fetal well-being, when placenta is infected by virulence factor, will lose barrier action,
Foetus health is injured, in order to improve pregnant and lying-in women's immunity, strengthens the barrier action of placenta, we are especially added with formula
The composition of the strengthen immunities such as VE, folic acid, beta carotene, garlic P.E;
(7) vitamin C can not only be by ferric iron back into ferrous iron, and can be chelated with iron and to form soluble small molecule network
Compound, be advantageous to iron absorption, iron is applied in combination with vitamin C according to specific proportioning in inventive formulation, improves iron absorptivity
3-6 times;
(8) pregnant and lying-in women's full function nutritious supplementary pharmaceutical effect general equilibrium of the present invention, includes the following effects factor:
1. the basic factor (milk powder, lactalbumin combination), establishes essential amino acid basis;
2. the cerebrum tonifying factor (DHA, phosphatide, taurine combination), preferentially ensures fetal brain development;
3. metabolic factor (4 big B family vitamin), ensureing pregnant and lying-in women's metabolic demand, promote embryo growth and development;
4. growth factor (calcium, iron, zinc), bioavilability is improved, meets embryo growth and development demand;
5. the prebiotic factor (galactooligosaccharide, FOS, polydextrose), promote proliferation of probiotics;
6. immune factor (VA, VC, calcium, iron, beta carotene, garlic P.E), improve immunity;
7. developing the factor (VA, beta carotene, DHA), the demand of fetus visual acuity is ensured.
Full function nutritional supplementation agent prescription of the present invention is reasonable, effect is comprehensive, edible safety, and through experiment, science takes this
Invention pregnant and lying-in women's full function nutritious supplementary pharmaceutical can promote pregnant and lying-in women to take in, and nutrition is balanced, significantly improves pregnant and lying-in women's immunity, promotees
Enter fetal brain and body development, prevention pregnant woman anemia and pregnancy syndrome.
Embodiment
Illustrate embodiments of the present invention below by way of specific instantiation, those skilled in the art can be by this specification
Disclosed content understands other advantages and effect of the present invention easily.The present invention can also pass through specific realities different in addition
The mode of applying is embodied or practiced, the various details in this specification can also be based on different viewpoints with application, without departing from
Various modifications or alterations are carried out under the spirit of the present invention.
Before the specific embodiment of the invention is further described, it should be appreciated that protection scope of the present invention is not limited to down
State specific specific embodiment;It is also understood that the term used in the embodiment of the present invention is specific specific in order to describe
Embodiment, the protection domain being not intended to be limiting of the invention.
When embodiment provides number range, it should be appreciated that except non-invention is otherwise noted, two ends of each number range
Any one numerical value can be selected between point and two end points.Unless otherwise defined, in the present invention all technologies for using and
Scientific terminology is identical with the meaning that those skilled in the art of the present technique are generally understood that.Except used in embodiment specific method, equipment,
Outside material, according to grasp of the those skilled in the art to prior art and the record of the present invention, it can also use and this
Any method, equipment and the material of the similar or equivalent prior art of method, equipment described in inventive embodiments, material come real
The existing present invention.
Embodiment 1
A kind of pregnant and lying-in women's full function nutritious supplementary pharmaceutical, it is made of the raw material of following weight parts:
Polydextrose 20;Skimmed milk powder 4.4;Whole-fat milk powder 6.5;Lactalbumin 3.3;Galactooligosaccharide 4.5;FOS
4.95;Oligoisomaltose 3.15;Lactose 7.3;Yam flour 3.8;Jujube powder 3.2;DHA algal oil 1.69;Corn syrup solid 24;
Sodium ascorbate 0.039;Casein sodium 0.72;Sodium citrate 1.21;Phosphatidase 2 .60;L-AA 0.18;Beta carotene
1.05;Nicotinic acid 0.015;Riboflavin 0.002;Axerophtholum aceticum 0.0022;D-VB5 calcium 0.015;Folic acid 0.0004;Tocopherol
0.012;Puridoxine hydrochloride 0.002;Thiamine hydrochloride 0.003;Cyanocobalamin 0.000003;Vitamine D3 0.000003;Taurine
0.12;Newborn mineral salt 1.9;Magnesium sulfate 0.46;Zinc gluconate 0.082;Sodium iron ethylene diamine tetra acetate 0.175;Casein phosphoric acid
Peptide 0.24.
Embodiment 2
A kind of pregnant and lying-in women's full function nutritious supplementary pharmaceutical, it is made of the raw material of following weight parts:
Polydextrose 20;Skimmed milk powder 4.4;Whole-fat milk powder 6.5;Lactalbumin 3.3;Galactooligosaccharide 4.5;FOS
4.95;Oligoisomaltose 3.15;Lactose 7.3;Yam flour 3.8;Jujube powder 3.2;DHA algal oil 1.69;Corn syrup solid 24;
Sodium ascorbate 0.039;Casein sodium 0.72;Sodium citrate 1.21;Phosphatidase 2 .60;L-AA 0.18;Beta carotene
1.05;Nicotinic acid 0.015;Riboflavin 0.002;Axerophtholum aceticum 0.0022;D-VB5 calcium 0.015;Folic acid 0.0004;Tocopherol
0.012;Puridoxine hydrochloride 0.002;Thiamine hydrochloride 0.003;Cyanocobalamin 0.000003;Vitamine D3 0.000003;Taurine
0.12;Newborn mineral salt 1.9;Magnesium sulfate 0.46;Zinc gluconate 0.082;Sodium iron ethylene diamine tetra acetate 0.175;Casein phosphoric acid
Peptide 0.24;Garlic P.E 1.15.
Pharmacodynamic experiment (one)
1. experiment purpose
Observe influence of the pregnant and lying-in women's full function nutritious supplementary pharmaceutical of the present invention to mouse immunity.
2. experiment material
2.1 given the test agent
Embodiment 1-2 pregnant and lying-in women's full function nutritious supplementary pharmaceutical.
Compound method:It is configured to suspension of the concentration as 100.0mg/ml respectively using water.
2.2 experimental animal
BALB/c mouse, 18-22g, female.
3. experiment packet and given the test agent give the time
Test and set four groups, respectively 1 group of embodiment, 2 groups of embodiment, commercial samples group and blank control group altogether, every group
10 mouse.
It is 45 days that each group sample, which gives the time,.
4. experimental method
4.1 principle
Mother cell breeder reaction occurs after T lymphocyte receptors ConA is stimulated, the line in living cells particularly proliferative cell
MTh (a kind of flaxen azoles nitrogen salt) can be decomposed into blue purple crystal by plastochondria hydrolase, and its OD value can reflect cell
Proliferative conditions.
4.2 instruments and material
RPMI1640 cell culture fluids, calf serum, 2 mercapto ethanol, penicillin, streptomysin, concanavalin A (ConA),
Hydrochloric acid, isopropanol, MTT, Hank, s liquid, PBS (PH7.2-7.4);
Gauze or 200 eye mesh screens, 24 well culture plates, 96 well culture plates (flat), operating theater instruments, CO2gas incubator,
ELIASA, 721 spectrophotometers, superclean bench, autoclave, sterile filters.
4.3 experimental procedure
4.3.1 preparation of reagents
Complete culture solution:RPMI1640 cell culture fluid filtration sterilizations, with 10% calf serum of preceding addition, 1% glutamy
Amine (200mmol/L), penicillin (100U/ml), streptomysin (100 μ g/L) and 5 × 10-5Mol/L 2 mercapto ethanol, use are sterile
1mol/L HCl or 1mol/L NaOH regulation PH to 7.0-7.2, that is, obtain complete culture solution.
ConA liquid:100 μ g/ml solution, filtration sterilization, in (- 20 DEG C) preservations of low temperature refrigerator are configured to distilled water.
Sterile Hank ' s liquid:With preceding with 3.5% sterile NaHCO3Adjust PH to 7.2-7.4.
MTT liquid:5mg MTT are dissolved in 1ml PH7.2 PBS, it is now with the current.
Acid isopropyl alcoholic solution:4ml 1mol/L HCl, prepared before use are added in 96ml isopropanols.
4.3.2 prepared by splenocyte suspension
It is sterile to take spleen, it is placed in and fills appropriate sterile Hank, in s liquid plates, gently ground spleen with tweezers, is made single thin
Born of the same parents' suspension.Spleen is ground through 200 mesh sieve net filtrations, or with 4 layers of gauze, is washed 2 times with Hank ' s liquid, centrifuges 10min every time
(1000r/min).Then cell is suspended in 1ml complete culture solution, (should be with platform phenol orchid dyeing counting viable count
More than 95%) it is 3 × 10, to adjust cell concentration6Individual/ml.
4.3.3 lymphproliferation response
Holes will be divided to add in 24 well culture plates per a splenocyte suspension, per hole 1ml, wherein a hole adds 75 μ lConA liquid
(equivalent to 7.5 μ g/ml), another hole are placed in 5%CO as control2, 72h is cultivated in 37 DEG C of incubators.Culture terminates preceding 4h, often
Hole gently sucks supernatant 0.7ml, adds 0.7ml and is free of the RPMI1640 nutrient solutions of calf serum, while adds MTT (5mg/
Ml) 50 μ l/ holes, continue to cultivate 4h.After culture terminates, 1ml acid isopropyl alcohol is added per hole, piping and druming mixes, and makes purple crystal complete
Fully dissolved.Then it is dispensed into 96 well culture plates, 3 parallel holes are made in each hole, and optical density is determined with 570nm wavelength with ELIASA
Value.Also lysate can be directly moved into 2ml cuvettes, OD values is determined in wavelength 570nm on 721 spectrophotometers.
4.3.4 result judgement
The propagation energy of lymphocyte is represented with adding the OD value of ConA fluid apertures to subtract to be not added with the OD value of ConA fluid apertures
Power, the optical density difference of test sample group are significantly higher than the optical density difference of control group, can determine that this experimental result positive.
5. experimental result
Living animal observation index
General clinical observation:Including but not limited to death condition, the state of mind, behavioral activity, morbidity, breathing, secretion,
Excrement and diet and drinking-water situation etc..
Detailed clinical is observed:The including but not limited to state of mind, behavioral activity, skin, hair, eyes, ear, nose, abdomen
Portion, external genital organs, anus, four limbs, foot and breathing.
Body weight:All animals after the receipt, before packet and dying preceding measure body weight.
Each experimental group optical density difference (with plus the OD value of ConA fluid apertures subtract and be not added with the OD value of ConA fluid apertures,
Take the difference average value of 10 mouse of each group) it is as shown in table 1 below:
Each experimental group optical density difference of table 1
Packet | n | Optical density difference |
Blank control group | 10 | 0.165±0.046 |
Commercial samples group | 10 | 0.444±0.151* |
1 group of embodiment | 10 | 0.793±0.123** |
2 groups of embodiment | 10 | 1.045±0.228** |
Note:Compared with blank control group:*P≤0.01;**P≤0.001.
From table 1 it follows that compared with blank control group, remaining each group optical density difference substantially increases, and prompts each group
The lymphopoiesis ability of mouse has strengthened.Comparatively, pregnant and lying-in women's full function nutritious supplementary pharmaceutical of the present invention (is implemented
Example 1 and commercially available nutritional supplement product 2) will be substantially better than to the improvement of mouse lymphocyte multiplication capacity.It is especially needed
, it is noted that embodiment 2 contains garlic P.E in being formulated, it improves immunity effect and protruded the most, adds so as to confirm
It is of great advantage to enter improvement of the garlic juice freeze-dried powder to pregnant and lying-in women's immunity, while turn avoid traditional garlic extract to intestines and stomach
Strong impulse acts on.
Pharmacodynamic experiment (two)
1. experiment purpose
Observe influence of the pregnant and lying-in women's full function nutritious supplementary pharmaceutical of the present invention to learning and memory in rats acquired disturbance.
2. experiment material
2.1 given the test agent
Embodiment 1-2 pregnant and lying-in women's full function nutritious supplementary pharmaceutical.
Compound method:It is configured to suspension of the concentration as 100.0mg/ml respectively using water.
2.2 experimental animal
SD rats, 5 week old, 120-140g, male and female half and half.
Experimental rat rearing conditions:22-27 DEG C of temperature, relative humidity 40-70%, freely intakes, feed, during daily illumination
Between be 8h, carry out adaptability raise one week.
3. experiment packet and given the test agent give the time
Test and set four groups, respectively 1 group of embodiment, 2 groups of embodiment, commercial samples group and blank control group altogether, every group
10 rats.
It is 45 days that each group sample, which gives the time,.
4. experimental method
4.1 modeling method
Experimental rat is allowed to drink 0.5g/L lead acetate water solution modeling daily, after continuing two weeks, high lead rat model is made
Mould success.
4.2 experimental method
With influence of the Shuttle box test given the test agent to resulted from chemical medicine learning and memory in rats Disorder Model.
5. experimental result
Living animal observation index
General clinical observation:Including but not limited to death condition, the state of mind, behavioral activity, morbidity, breathing, secretion,
Excrement and diet and drinking-water situation etc..
Detailed clinical is observed:The including but not limited to state of mind, behavioral activity, skin, hair, eyes, ear, nose, abdomen
Portion, external genital organs, anus, four limbs, foot and breathing.
Body weight:All animals after the receipt, before packet and dying preceding measure body weight.
Each experimental group rat active avoidance number and active avoidance time (taking 10 rat average values of each group) are such as table 2 below institute
Show:
Each experimental group rat active avoidance number of table 2 and active avoidance time
Packet | n | Active avoidance number | The active avoidance time (S) |
Blank control group | 10 | 8.6±3.7 | 133.5±51.0 |
Commercial samples group | 10 | 9.4±5.3 | 136.4±70.6 |
1 group of embodiment | 10 | 17.1±5.8* | 65.9±20.4* |
2 groups of embodiment | 10 | 17.6±4.2* | 63.5±22.8* |
Note:Compared with blank control group:*P≤0.05.
From Table 2, it can be seen that compared with blank control group, the commercially available nutritional supplement product group rat active avoidance time
With the basic indifference of active avoidance number, pregnant and lying-in women's full function nutritious supplementary pharmaceutical (Examples 1 and 2) group rat of the present invention is actively
Avoid number increase, the active avoidance time is reduced, and is shown that nutritious supplementary pharmaceutical of the present invention has and is promoted brain development, improves memory
Effect.
The preferred embodiments of the disclosure and embodiment are explained in detail above, but the present invention is not limited to
The above-described embodiment and examples, in those skilled in the art's possessed knowledge, the present invention can also not departed from
Various changes can be made on the premise of design.
Claims (10)
1. a kind of pregnant and lying-in women's full function nutritious supplementary pharmaceutical, it is characterised in that it is made of the raw material of following weight parts:It is poly-
Glucose 12-30;Skimmed milk powder 3.9-5.4;Whole-fat milk powder 6.4-6.7;Lactalbumin 3.2-3.5;Galactooligosaccharide 4.1-
5.2;FOS 4.65-5.80;Oligoisomaltose 3.03-3.25;Lactose 7.2-7.5;Yam flour 3.6-4.0;Jujube powder
3.0-3.2;DHA algal oil 1.65-1.72;Corn syrup solid 20-28;Sodium ascorbate 0.037-0.049;Casein sodium
0.65-0.82;Sodium citrate 0.93-1.49;Phosphatidase 2 .52-2.70;L-AA 0.16-0.20;Beta carotene 0.85-
1.45;Nicotinic acid 0.005-0.035;Riboflavin 0.001-0.006;Axerophtholum aceticum 0.0009-0.0042;D-VB5 calcium
0.002-0.075;Folic acid 0.0002-0.0009;Tocopherol 0.009-0.024;Puridoxine hydrochloride 0.001-0.006;Hydrochloric acid sulphur
Amine element 0.001-0.006;Cyanocobalamin 0.000001-0.000012;Vitamine D3 0.000001-0.000013;Taurine
0.08-0.15;Newborn mineral salt 1.6-2.7;Magnesium sulfate 0.26-0.70;Zinc gluconate 0.052-0.126;Ethylenediamine tetra-acetic acid
Ferrisodium 0.105-0.625;CPP 0.23-0.26.
2. pregnant and lying-in women's full function nutritious supplementary pharmaceutical as claimed in claim 1, wherein the parts by weight of each raw material are:Polydextrose
20;Skimmed milk powder 4.4;Whole-fat milk powder 6.5;Lactalbumin 3.3;Galactooligosaccharide 4.5;FOS 4.95;Oligomeric different malt
Sugar 3.15;Lactose 7.3;Yam flour 3.8;Jujube powder 3.2;DHA algal oil 1.69;Corn syrup solid 24;Sodium ascorbate
0.039;Casein sodium 0.72;Sodium citrate 1.21;Phosphatidase 2 .60;L-AA 0.18;Beta carotene 1.05;Nicotinic acid
0.015;Riboflavin 0.002;Axerophtholum aceticum 0.0022;D-VB5 calcium 0.015;Folic acid 0.0004;Tocopherol 0.012;Salt
Sour pyridoxol 0.002;Thiamine hydrochloride 0.003;Cyanocobalamin 0.000003;Vitamine D3 0.000003;Taurine 0.12;Breast
Mineral salt 1.9;Magnesium sulfate 0.46;Zinc gluconate 0.082;Sodium iron ethylene diamine tetra acetate 0.175;CPP 0.24.
3. pregnant and lying-in women's full function nutritious supplementary pharmaceutical as claimed in claim 1, it is characterised in that nutritional supplementation described in per 100g
Nutritional ingredient containing following weight in agent:
Protein 9.5-10.2g;Fatty 5.2-5.4g;Carbohydrate 50.5-53.0g;Dietary fiber 22.5-24.0g;
Sodium 108-112mg;Vitamin A 1350-1365 μ g;Vitamin D 1.8-2.0 μ g;Vitamin E 14.85-15.05mg;Dimension life
Plain B1 1.65-1.72mg;Vitamin B2 1.66-1.70mg;Vitamin B6 1.66-1.70mg;Vitamin B12 4.64-
4.70μg;Vitamin C 185.0-185.6mg;Nicotinic acid 20.60-20.75mg;Folic acid 368-378 μ g;Pantothenic acid 5.45-
5.55mg;Magnesium 136-141mg;Calcium 990-1020mg;Iron 18.4-18.7mg;Zinc 13.79-13.82mg;Taurine 119-
123mg。
4. pregnant and lying-in women's full function nutritious supplementary pharmaceutical as claimed in claim 3, under often containing in nutritious supplementary pharmaceutical described in 100g
State the nutritional ingredient of weight:
Protein 9.8g;Fatty 5.3g;Carbohydrate 52.0g;Dietary fiber 23.5g;Sodium 110mg;Vitamin A
1360μg;The μ g of vitamin D 1.9;Vitamin E 15.00mg;Vitamin B1 1.68mg;Vitamin B2 1.68mg;Vitamin B6
1.68mg;The μ g of vitamin B12 4.67;Vitamin C 185.4mg;Nicotinic acid 20.70mg;The μ g of folic acid 376;Pantothenic acid 5.49mg;
Magnesium 140mg;Calcium 1000mg;Iron 18.6mg;Zinc 13.80mg;Taurine 120mg.
5. pregnant and lying-in women's full function nutritious supplementary pharmaceutical as claimed in claim 1, pregnant and lying-in women's full function nutrition is made and mends
Filling the raw material of agent also includes following weight parts:Garlic P.E 1.05-1.20.
6. pregnant and lying-in women's full function nutritious supplementary pharmaceutical as claimed in claim 5, the garlic P.E pass through following method systems
:Fresh garlic is taken to be squeezed the juice after removing the peel, gained squeezeding juice utilizes the ultrafiltration that molecular weight is 500-600 of damming through centrifuged supernatant
Film carries out ultrafiltration, and garlic P.E is obtained after gained filtrate is freeze-dried.
7. pregnant and lying-in women's full function nutritious supplementary pharmaceutical as claimed in claim 6, wherein the parts by weight of each raw material are:Polydextrose
20;Skimmed milk powder 4.4;Whole-fat milk powder 6.5;Lactalbumin 3.3;Galactooligosaccharide 4.5;FOS 4.95;Oligomeric different malt
Sugar 3.15;Lactose 7.3;Yam flour 3.8;Jujube powder 3.2;DHA algal oil 1.69;Corn syrup solid 24;Sodium ascorbate
0.039;Casein sodium 0.72;Sodium citrate 1.21;Phosphatidase 2 .60;L-AA 0.18;Beta carotene 1.05;Nicotinic acid
0.015;Riboflavin 0.002;Axerophtholum aceticum 0.0022;D-VB5 calcium 0.015;Folic acid 0.0004;Tocopherol 0.012;Salt
Sour pyridoxol 0.002;Thiamine hydrochloride 0.003;Cyanocobalamin 0.000003;Vitamine D3 0.000003;Taurine 0.12;Breast
Mineral salt 1.9;Magnesium sulfate 0.46;Zinc gluconate 0.082;Sodium iron ethylene diamine tetra acetate 0.175;CPP 0.24;
Garlic P.E 1.15.
8. pregnant and lying-in women's full function nutritious supplementary pharmaceutical as described in claim any one of 1-7, it is characterised in that the pregnant and lying-in women
It is complete that this pregnant and lying-in women is further made by the conventional method for preparing electuary or chewable tablet in this area in full function nutritious supplementary pharmaceutical
Functional form nutritious supplementary pharmaceutical electuary or chewable tablet.
9. the answering in pregnant and lying-in women's food is prepared of pregnant and lying-in women's full function nutritious supplementary pharmaceutical as described in claim any one of 1-7
With.
10. pregnant and lying-in women's full function nutritious supplementary pharmaceutical as described in claim any one of 1-7 is in health care for pregnant and puerperal women product are prepared
Application.
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CN109691606A (en) * | 2017-11-24 | 2019-04-30 | 上海冬泽特医食品有限公司 | A kind of beverage taken when the production for puerpera |
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CN110771869A (en) * | 2019-09-29 | 2020-02-11 | 亨美久健康科技(广东)有限公司 | Third-stage full-nutrition breakfast for pregnant women and preparation method thereof |
CN110771870A (en) * | 2019-09-29 | 2020-02-11 | 亨美久健康科技(广东)有限公司 | Second-stage full-nutrition breakfast for pregnant women and preparation method thereof |
CN110720632A (en) * | 2019-12-03 | 2020-01-24 | 吉林省红五味生物技术有限公司 | Nutrient composition for late pregnancy and preparation method and application thereof |
CN111602719A (en) * | 2020-05-11 | 2020-09-01 | 呼伦贝尔双娃乳业有限公司 | Organic formula milk powder for pregnant and lying-in women |
CN117122054A (en) * | 2023-09-05 | 2023-11-28 | 广西金品燕庄食品有限责任公司 | Instant bird's nest product formula suitable for pregnant women |
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