CN107691838A - Pet sterilization sustained release cream and preparation method thereof - Google Patents
Pet sterilization sustained release cream and preparation method thereof Download PDFInfo
- Publication number
- CN107691838A CN107691838A CN201710852254.XA CN201710852254A CN107691838A CN 107691838 A CN107691838 A CN 107691838A CN 201710852254 A CN201710852254 A CN 201710852254A CN 107691838 A CN107691838 A CN 107691838A
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- Prior art keywords
- vitamin
- cream
- sterilization
- extract
- sustained release
- Prior art date
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- Granted
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Classifications
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- A—HUMAN NECESSITIES
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-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
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Abstract
The invention discloses a kind of pet sterilization sustained release cream and preparation method thereof is provided, its component includes by mass percentage：0.1% 3% Astragalus Root P.Es, 0.1% 3% aloe extracts, 0.1% 2% ginseng extracts, 0.1% 2% ophiopogon japonicus extracts, 0.1% 2% Schisandra chinens P.Es, 5% 15% milk powder, 2% 10% chicken liver meals, 2% 10% fish meal, 0.5% 3% lecithin, 5% 15% white sugar, 1% 10% maltose, 0.5% 3% FOSs, 0.5% 3% sodium carboxymethylcelluloses, 10% 18% Ns of hydrolysis cream, 10% 18% fish oil, 0.1% 0.35% sodium benzoates, 0.001% vitamin A, 0.02% vitamin B1, 0.02% vitamin B2, 0.5% vitamin C, 0.2% vitamin E, 0.5% zinc sulfate, surplus is water.Thus, the sterilization in the present invention is sustained the component of effect and can be efficiently absorbed, and can alleviate pet negative emotions after sterilization operation, accelerates wound healing, and enhancing is immune.
Description
Technical field
The present invention relates to pet care product field, more particularly to pet sterilization sustained release cream and preparation method thereof.
Background technology
Sterilization can control the Population of dog cat, especially for the quantity of control wandering dog cat；Bitch or mother can be avoided
Cat suffers from a series of relevant diseases, such as reduces the risk that bitch (cat) suffers from breast cancer, and the diseases such as the risk of pyrometra are suffered from elimination；Drop
Probability of hyperplasia of prostate and infection etc. occurs for low public dog or tom.Deepen with the main understanding to dog cat sterilization necessity is doted on,
More and more dote on it is main dog cat can be helped to carry out sterilization operation, but wound healing occurs in many dog cats after sterilization operation is finished
Slowly, immunocompromised, it is depressed situations such as, but at present on the market without alleviation dog cat sterilization after negative effect product.
The content of the invention
In order to solve the one or more of problem above, there is provided a kind of pet sterilization sustained release cream and preparation method thereof.
According to an aspect of the present invention, there is provided a kind of pet sterilization is sustained cream, and its component includes by mass percentage：
0.1%-3% Astragalus Root P.Es, 0.1%-3% aloe extracts, 0.1%-2% ginseng extracts, the 0.1%-2% tubers of dwarf lilyturf extract
Thing, 0.1%-2% Schisandra chinens P.Es, 5%-15% milk powder, 2%-10% chicken liver meals, 2%-10% fish meal, 0.5%-3% ovum
Phosphatide, 5%-15% white sugar, 1%-10% maltose, 0.5%-3% FOSs, 0.5%-3% sodium carboxymethylcelluloses,
10%-18% oxen hydrolyze cream, 10%-18% fish oil, 0.1%-0.35% sodium benzoates, 0.001% vitamin A, 0.02% dimension
Raw plain B1,0.02% vitamin B2,0.5% vitamin C, 0.2% vitamin E, 0.5% zinc sulfate, surplus is water.
In some embodiments, Astragalus Root P.E 0.8%, aloe extract 0.8%, ginseng extract 0.5%, the tuber of dwarf lilyturf
Extract 0.5%, Schisandra chinens P.E 0.5%, milk powder 9.5%, chicken liver meal 5.5%, fish meal 5.5%, lecithin 1.5%, in vain
Sugar 10%, maltose 3%, FOS 1%, sodium carboxymethylcellulose 2%, ox hydrolysis cream 13%, fish oil 13%, sodium benzoate
0.15%, water 31.509%.
According to another aspect of the present invention, a kind of method for preparing foregoing pet sterilization sustained release cream is additionally provided, its
It is characterised by, comprises the following steps,
(1) Astragalus Root P.E, aloe extract, ginseng extract, ophiopogon japonicus extract, Schisandra chinens P.E, milk powder, chicken gizzard
Powder, fish meal, lecithin, white sugar, maltose, FOS, ox hydrolysis cream, fish oil are weighed in input material-compound tank by formula rate, pressed
Formula rate adds water homogenisation and stirs into slurry；Then sodium carboxymethylcellulose is weighed by formula rate again and adds material-compound tank；
(2) that opens material-compound tank enters vapour switch, when step (1) products therefrom is heated into 70~80 DEG C while stirring；
(3) by step (2) products therefrom stirring boil after sequentially add by formula rate weigh gained vitamins and
Sodium benzoate continues to boil and keeps fluidized state 20~30 minutes into material-compound tank；
(4) mixture of step (3) is cooled down into obtain final product.
In some embodiments, material-compound tank is steamed ingredients tank.
In some embodiments, the steam pressure in the material-compound tank in step (2) and (3) is 0.2-0.4MPa.
The present invention compared with prior art, has the advantages that：After the quickening dog cat sterilization operation of sterilization sustained release cream
Wound healing, alleviate the active ingredient of postoperative negative emotions in sterilization release sustaining component, such as Astragalus Root P.E, aloe extraction
Thing, ginseng extract, ophiopogon japonicus extract, Schisandra chinens P.E etc., its specific active component content are as follows：
Astragalus Root P.E：Contain astragalus polyose in Astragalus Root P.E, non-specific immune function and body fluid can be significantly increased
Immunologic function, cellular immune function is low after can correcting wound, has antibacterial, antiviral, anti-oxidation function.
Aloe extract：Heat-clearing cool liver, invigorating the spleen, lead to intestines；Anthracene ketone compounds in aloe have mostly sterilization, it is antibacterial,
Anti-inflammatory, removing toxic substances, promote the effect such as wound healing, skin can be repaired, improve scar.
Ginseng extract：The active component ginsenoside contained in ginseng extract can strengthen immunity of organisms, quick extensive
The effect of complex matter；The healing of post-operative wound and the recovery of muscle power can be strengthened.
Ophiopogon japonicus extract：Modern pharmacological research also indicates that, the tuber of dwarf lilyturf mainly glycosides containing dwarf lilyturf, steroid saponin, alkaloid, paddy steroid
Alcohol, glucose, amino acid, vitamin etc., there is antifatigue, removing free radical, improve cellular immune function.
Schisandra chinens P.E：With restraining astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, the effect of kidney calming；Clinical efficacy shows, the fruit of Chinese magnoliavine
Can effective fatigue-relieving.
Lecithin：Improve the power of regeneration of the metabolic capability of human body, self-healing ability and antibody tissue.
FOS：Utilized by beneficial bacteriums such as Bifidobacteriums, suppress external source pathogenic bacteria and the intrinsic putrefactivebacteria of enteral such as sand
The growth and breedings such as door Salmonella, reduce the growth and accumulation of enteral corrupt substance, promote intestines peristalsis, prevent constipation and diarrhoea, can
Strengthen immunity of organisms, promote the absorption of the absorption of nutrition, especially calcium, enhancing development and prevent osteoporosis, together
When may additionally facilitate the self-assembling formation of vitamin B1, B2, B3, B6, B12 and folic acid, so as to improve human metabolism's level, improve
Immunity and premunition.
Vitamin A：Safeguard the health of Epithelial cell and promote the synthesis of immunoglobulin, help to protect epidermis,
Mucous membrane is not by bacterial infestation, healthy skin.
Vitamin B1：Promote enterogastric peristalsis, increase appetite.
Vitamin B2：Promote development and the regeneration of cell, prevention is with eliminating scytitis reaction.
Vitamin C：Antioxidant, protection body prevent melanin from being formed from the threat of free radical.
Vitamin E：Antioxidation activity can be strengthened, protect the skin from the injury of ultraviolet and pollution, reduce scar and color
The deposition of element, accelerates the healing of wound.
Zinc sulfate：Zinc is advantageous to the merisis of epidermal cell, accelerates the formation of wound new granulation tissue, strengthens muscle
The ability of collagenous fibres is produced, cicatrizes a wound faster, more preferably so as to improve the concentration of Zn in serum, while also help sense
The prevention and control of dye, promote the healing of wound and wound.
Above-mentioned dispensing is coordinated by special ratios to be added sterilization and is sustained in cream, and there is sterilization to be sustained the component of effect can be by
Effectively absorb, pet negative emotions after sterilization operation can be alleviated, accelerate wound healing, enhancing is immune.
Embodiment
First, prepared by sterilization sustained release cream
Embodiment 1：
Raw material has been weighed respectively, raw material total amount is 100 kilograms, wherein, 0.1 kilogram of Astragalus Root P.E, aloe extract 0.1
Kilogram, 0.1 kilogram of ginseng extract, 0.1 kilogram of ophiopogon japonicus extract, 0.1 kilogram of Schisandra chinens P.E, 15 kilograms of milk powder, chicken gizzard
2 kilograms of powder, 10 kilograms of fish meal, 3 kilograms of lecithin, 15 kilograms of white sugar, 1 kilogram of maltose, 3 kilograms of FOS, carboxymethyl cellulose
Plain 0.5 kilogram of sodium, ox 18 kilograms of cream of hydrolysis, 10 kilograms of fish oil, 0.15 kilogram of sodium benzoate, 0.001 kilogram of vitamin A, dimension life
Plain 0.02 kilogram of B1,0.02 kilogram of vitamin B2,0.5 kilogram of vitamin C, 0.2 kilogram of vitamin E, zinc sulfate 0.5 are public
Jin, 20.609 kilograms of water.
Specific preparation technology is as follows：
(1) Astragalus Root P.E, aloe extract, ginseng extract, ophiopogon japonicus extract, Schisandra chinens P.E, milk powder, chicken gizzard
Powder, fish meal, lecithin, white sugar, maltose, FOS, ox hydrolysis cream, fish oil are weighed in input material-compound tank by formula rate, pressed
Formula rate adds water homogenisation and stirs into slurry；Sodium carboxymethylcellulose is weighed by formula rate and adds steamed ingredients
Tank；
(2) that opens steamed ingredients tank enters vapour switch, and step (1) products therefrom is heated into 70~80 while stirring
DEG C when, the steam pressure in steamed ingredients tank is 0.2-0.4MPa；
(3) sequentially added after the stirring of step (2) products therefrom is boiled and weigh gained, vitamin A, dimension by formula rate
Raw plain B1, vitamin B2, vitamin C kilogram, vitamin E and sodium benzoate continue to boil 20-30 into steamed ingredients tank
Minute.
(4) mixture of step (3) is cooled down into obtain final product.
Embodiment 2：
Raw material total amount is 100 kilograms, wherein, 0.8 kilogram of Astragalus Root P.E, 0.8 kilogram of aloe extract, ginseng extract
0.5 kilogram, 0.5 kilogram of ophiopogon japonicus extract, 0.5 kilogram of Schisandra chinens P.E, 9.5 kilograms of milk powder, 5.5 kilograms of chicken liver meal, fish meal
5.5 kilograms, 1.5 kilograms of lecithin, 10 kilograms of white sugar, 3 kilograms of maltose, 1 kilogram of FOS, 2 kilograms of sodium carboxymethylcellulose,
Ox hydrolyzes 13 kilograms of cream, 13 kilograms of fish oil, 0.15 kilogram of sodium benzoate, 0.001 kilogram of vitamin A, the public affairs of vitamin B1 0.02
Jin, 0.02 kilogram of vitamin B2,0.5 kilogram of vitamin C, 0.2 kilogram of vitamin E, 0.5 kilogram of zinc sulfate, water 31.509 are public
Jin.
Preparation technology is the same as embodiment 1.
Embodiment 3：
Raw material total amount is 100 kilograms, wherein, 3 kilograms of Astragalus Root P.E, 3 kilograms of aloe extract, the public affairs of ginseng extract 2
Jin, 2 kilograms of ophiopogon japonicus extract, 2 kilograms of Schisandra chinens P.E, 5 kilograms of milk powder, 10 kilograms of chicken liver meal, 2 kilograms of fish meal, lecithin
0.5 kilogram, 5 kilograms of white sugar, 10 kilograms of maltose, 0.5 kilogram of FOS, 3 kilograms of sodium carboxymethylcellulose, the public affairs of ox hydrolysis cream 10
Jin, 18 kilograms of fish oil, 0.15 kilogram of sodium benzoate, 0.001 kilogram of vitamin A, 0.02 kilogram of vitamin B1, vitamin B2
0.02 kilogram, 0.5 kilogram of vitamin C, 0.2 kilogram of vitamin E, 0.5 kilogram of zinc sulfate, 22.609 kilograms of water.
Preparation technology is the same as embodiment 1.
The component being related in above example 1 to embodiment 3 is all commercially available and obtains, fish oil be extract therefrom it is full
And aliphatic acid, there is the absorption for promoting liposoluble vitamin.
The acceptance criteria of wherein Astragalus Root P.E is that astragalus polyose content is 30%, and the acceptance criteria of ginseng extract is people
It is 30% to join saponin content, and aloe extract is aloe xeraphium, and the withdrawal ratio of ophiopogon japonicus extract and Schisandra chinens P.E is
10:1, above extract provides by Beijing Sheng Meikang bio tech ltd.
2nd, sterilization sustained release cream clinical effectiveness experiment
Sterilization sustained release cream can effectively facilitate the operation of the reproductive systems such as dog cat sterilization, the wound healing of abdominal postoperative, alleviate
The function nutriment of postoperative pet negative emotions.This experiment chooses the postoperative sterilization female cat of health as experimental study object, than
Compared with the clinical efficacy of analysis sterilization sustained release cream.
(1) experimental animal：The healthy female cat (August age~2 year old) 80 of sterilization operation need to be carried out by choosing, and avoid oestrus
Carry out basic operation identical sterilization operation (using tangent, extracing whole uterus, the suture of art mouth tubercle).
(2) test sample：Embodiment 1.2.3 according to sterilization sustained release paste formulation is made respectively, forms three kinds of edible cream
Body is standby.
(3) it is grouped：Female cat of random selection sterilization is grouped, and is provided with control group i.e. postoperative sterilization and is not raised
Feed sterilization sustained release cream group 20；Test group is postoperative sterilization feeding sterilization sustained release cream test group 60, is divided into three scheme groups, in detail
It is shown in Table 1.It is postoperative to carry out identical basic nursing, free choice feeding (cat food of same manufacturer production) and drinking-water.Each group is until 1
After week take out stitches disinfecting.
The experiment packet of table 1
(4) effect assessment
(1) poor healing rate situation：Taken out stitches after one week and wound is checked when handling, wound infection (suppurating, ulceration), wound are hard
Knot, the reaction of obvious scar are poor healing.Poor healing rate %=poor healings number of cases/total number of cases × 100
(2) observation of wound healing time：Record every sterilization cat of each group art mouth healing time, wound healing standard with
Surface of a wound area is less than the 5% of the gross area, or healing area is more than 95% for healing completely.
(3) negative emotions are reacted：It is possible that the mood such as anxiety, fear, depression, pays attention to observing and remembering after female cat sterilization
There is the quantity of such situation in record, and feeding re-records once after one week.
(5) result
(1) poor wound healing situation when taking out stitches
Compare between each group, the poor wound healing rate of each experimental group is below control group, it can be seen that, sterilization sustained release cream pair
The tool for reducing poor wound healing incidence has certain effect, and the effect of embodiment 2 is better than embodiment 1 and embodiment 3, in detail
It is shown in Table 2.
The poor healing rate (example, %) of table each group after 2 one weeks
(2) observation of wound healing time
One group of scheme, two groups, three groups of wound healing time compared with control group, having significant difference, (variance is neat, P
＜ 0.05), it can be seen that, sterilization sustained release cream can promote wound to heal early, and the effect of embodiment 2 is better than embodiment 1 and in fact
Example 3 is applied, refers to table 3.
The comparison (n=20, day/d) of each group wound healing time of table 3
Note：* P ＜ 0.05 are represented, compared with control group, there is significant difference.
(3) negative emotions situation
Compare between each group, the negative emotions remission rate of each experimental group, be above control group, it can be seen that, sterilization sustained release cream
There is certain mitigation to the negative emotions after female cat sterilization, and the effect of embodiment 2 is better than embodiment 1 and embodiment 3,
Refer to table 4.
The each group negative condition of table 4 alleviates situation (example, %)
In summary, sterilization sustained release cream can reduce the poor wound healing incidence of sterilization stepmother cat, shorten its wound
Healing time, alleviate postoperative negative emotions, and embodiment 2 is to reach the scheme of optimum efficiency.
Above-described is only some embodiments of the present invention.For the person of ordinary skill of the art, not
On the premise of departing from the invention design, various modifications and improvements can be made, these belong to the protection model of the present invention
Enclose.
Claims (5)
1. pet sterilization is sustained cream, it is characterised in that its component includes by mass percentage：
0.1%-3% Astragalus Root P.Es, 0.1%-3% aloe extracts, 0.1%-2% ginseng extracts, the 0.1%-2% tubers of dwarf lilyturf
Extract, 0.1%-2% Schisandra chinens P.Es, 5%-15% milk powder, 2%-10% chicken liver meals, 2%-10% fish meal, 0.5%-
3% lecithin, 5%-15% white sugar, 1%-10% maltose, 0.5%-3% FOSs, 0.5%-3% carboxymethyl celluloses
Sodium, 10%-18% oxen hydrolysis cream, 10%-18% fish oil, 0.1%-0.35% sodium benzoates, 0.001% vitamin A, 0.02%
Vitamin B1,0.02% vitamin B2,0.5% vitamin C, 0.2% vitamin E, 0.5% zinc sulfate, surplus are water.
2. pet sterilization according to claim 1 is sustained cream, it is characterised in that the Astragalus Root P.E 0.8%, aloe carries
Take thing 0.8%, ginseng extract 0.5%, ophiopogon japonicus extract 0.5%, Schisandra chinens P.E 0.5%, milk powder 9.5%, chicken liver meal
5.5%, fish meal 5.5%, lecithin 1.5%, white sugar 10%, maltose 3%, FOS 1%, sodium carboxymethylcellulose 2%, ox
Hydrolyze cream 13%, fish oil 13%, sodium benzoate 0.15%, water 31.509%.
3. it is a kind of prepare described in any one of claims 1 to 3 pet sterilization sustained release cream method, it is characterised in that including with
Lower step,
(1) Astragalus Root P.E, aloe extract, ginseng extract, ophiopogon japonicus extract, Schisandra chinens P.E, milk powder, chicken liver meal,
Fish meal, lecithin, white sugar, maltose, FOS, ox hydrolysis cream, fish oil is weighed in input material-compound tank by formula rate, by formula
Ratio adds water homogenisation and stirs into slurry；Then sodium carboxymethylcellulose is weighed by formula rate again and adds material-compound tank；
(2) that opens material-compound tank enters vapour switch, when step (1) products therefrom is heated into 70~80 DEG C while stirring；
(3) vitamins and benzene first that gained is weighed by formula rate are sequentially added after the stirring of step (2) products therefrom is boiled
Sour sodium continues to boil and keeps fluidized state 20~30 minutes into material-compound tank；
(4) mixture of step (3) is cooled down into obtain final product.
4. the preparation method of pet sterilization sustained release cream according to claim 4, it is characterised in that the material-compound tank is steam
Warm ingredients tank.
5. the preparation method of pet sterilization sustained release cream according to claim 4, it is characterised in that the step (2) and (3)
In material-compound tank in steam pressure be 0.2-0.4MPa.
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| CN109331113A (en) * | 2018-09-21 | 2019-02-15 | 深圳市红瑞生物科技有限公司 | Assist in the treatment of the prescription cream and preparation method thereof of pet diabetes |
| CN110720552A (en) * | 2019-11-07 | 2020-01-24 | 辽宁中医药大学 | Pet Chinese herbal medicine cat food for health care of adult sterile female pet cats and preparation method thereof |
| CN111357870A (en) * | 2020-03-23 | 2020-07-03 | 上海信元宠物食品有限公司 | Recovery period pet diet for wound healing |
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