CN107340400A - A kind of sample injection method and device for blood sample detection - Google Patents

A kind of sample injection method and device for blood sample detection Download PDF

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Publication number
CN107340400A
CN107340400A CN201610281615.5A CN201610281615A CN107340400A CN 107340400 A CN107340400 A CN 107340400A CN 201610281615 A CN201610281615 A CN 201610281615A CN 107340400 A CN107340400 A CN 107340400A
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CN
China
Prior art keywords
sample
slideway
pipe support
longitudinal
horizontal transfer
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CN201610281615.5A
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Chinese (zh)
Inventor
陈生
贠立新
肖继昌
谢凡
郭树林
邱焕波
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Shandong Talentine Medical Technology Co Ltd
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Shandong Talentine Medical Technology Co Ltd
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Priority to CN201610281615.5A priority Critical patent/CN107340400A/en
Publication of CN107340400A publication Critical patent/CN107340400A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1081Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
    • G01N35/109Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with two horizontal degrees of freedom
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1002Reagent dispensers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065Multiple transfer devices
    • G01N35/1074Multiple transfer devices arranged in a two-dimensional array
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027General features of the devices
    • G01N2035/1048General features of the devices using the transfer device for another function
    • G01N2035/1058General features of the devices using the transfer device for another function for mixing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065Multiple transfer devices
    • G01N2035/1076Multiple transfer devices plurality or independently movable heads

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The present invention relates to a kind of sample injection method and device for blood sample detection, using full-automatic sampling device, including laterally input slideway, horizontal transfer slideway, longitudinal sample introduction slideway, longitudinal direction allotment slideway, sample tube identifier, sample tube mark scan device and sample-adding needle device;Operating procedure is:Sample pipe support is transported to laterally input slideway or horizontal transfer slideway by longitudinal direction allotment slideway, is recorded sample pipe support number and sample pore number and is stored;Laterally sample pipe support is transported to longitudinal sample introduction slideway scanned samples pipe mark and sample drawn by input slideway;Horizontal transfer slideway collects the sample pipe support sampled and is transported to longitudinal direction allotment slideway, and longitudinal direction allocates slideway and the sample pipe support sampled is transported into export section.The present invention is allocated to sample pipe support using Computer Control Technology according to the positional information of sample pipe support, ensures that sample pipe support is orderly, efficiently conveys sample introduction, avoid operator from directly being contacted with blood sample and influence the accuracy of detection.

Description

A kind of sample injection method and device for blood sample detection
Technical field
The present invention relates to the conveying of blood sample, and in particular to a kind of sample injection method and dress for blood sample detection Put.
Background technology
Chinese patent 200920172819.0 discloses a kind of full-automatic measure blood viscosity, the equipment of blood pressure, there is one Support, the support be provided with stirring needle device, sample-adding needle device, type capillary viscosity measurement device, based on computer installation from Dynamic control circuit and matcher;The side of testing stand sets sample pipe support input slideway, and opposite side sets sample pipe support defeated Go out slideway;The outlet of the sample pipe support input slideway connects with the entrance of a sample pipe support stepping slideway;The testboard Rotary blood flow measurement device, cleaning slot device are set gradually on face, two-dimensional movement work is set above the testing stand Make device, the two-dimensional movement equipment includes transverse moving mechanism, vertically to travel mechanism, the stirring needle device and sample-adding Needle device is arranged on the two-dimensional movement equipment;The first test position of the sample pipe support stepping slideway sets hematocrit to scan Determine device.The full-automatic detection mode of the equipment, improve the test speed and accuracy of clinical examination.But this sets Standby to carry out full-automatic allotment to high-volume sample pipe support, sample introduction efficiency is not high.
The content of the invention
It is an object of the invention to provide a kind of sample injection method and device for blood sample detection, full-automatic sampling device Including laterally input slideway, horizontal transfer slideway, longitudinal sample introduction slideway, longitudinal direction allotment slideway, sample tube identifier, sample tube mark Remember scanning means, sample-adding needle device and automatic control circuit;The full-automatic input mode of the present invention is based on Computer Control Technology, Automatic identification and allotment can be carried out to the sample pipe support being continuously introduced into, ensure the progress of sample introduction rational and orderly, improve blood sample The efficiency of this detection.
It is an object of the invention to what is realized by following technical proposals:It is a kind of to enter sample prescription for blood sample detection Method, using a kind of full-automatic sampling device, the full-automatic sampling device includes one and laterally inputs slideway, a plurality of horizontal transfer Slideway, a longitudinal sample introduction slideway, a longitudinal direction allotment slideway, pipe support is set on longitudinal sample introduction slideway to be loaded into mouth and multiple Pipe support diffluence pass, the longitudinal direction allotment installation of slide track import section, export section, pipe support allotment mouth and pipe support dispensing opening;It is described Sample tube identifier is set on longitudinal direction allotment slideway, along the longitudinal sample introduction slideway order set sample tube mark scan device and It is loaded needle device;Operating procedure is:
Sample pipe support is sequentially placed into the importing section of longitudinal direction allotment slideway, full-automatic sampling device starts, and order is vertical A, Rear port to allotment slideway by sample pipe support sequentially-fed to the horizontal input port or horizontal transfer slideway for inputting slideway, sample This pipe identifier records the sample pipe support number of each sample tube and sample pore number and stored;
B, when sample pipe support reaches the laterally input port of input slideway, laterally input slideway and start, sample pipe support is suitable Sequence is collected into laterally in input slideway;Then pipe support that sample pipe support is transported to longitudinal sample introduction slideway is loaded into mouth;
When being laterally fully loaded with sample pipe support in input slideway, horizontal transfer slideway starts, by follow-up sample pipe support order It is collected into horizontal transfer slideway;When being fully loaded with sample pipe support in first horizontal transfer slideway, Article 2 transverse direction transfer slideway Start, follow-up sample pipe support order is collected into Article 2 transverse direction transfer slideway;
C, when the pipe support that sample pipe support reaches longitudinal sample introduction slideway is loaded into mouth, longitudinal sample introduction slideway is ordered by sample pipe support To mark scan position, sample tube mark scan device starts sequentially-fed, each according to the sample pore journal Label information and storage in sample tube;
D, after the completion of mark scan, longitudinal sample introduction slideway is ordered by sample pipe support sequentially-fed to sample position, sample needle Device starts, and the blood sample in each sample tube is extracted according to the sample pore order;
E, after the completion of sampling, longitudinal sample introduction slideway is ordered by the sample pipe support sequentially-fed sampled to horizontal transfer slideway Front port;
F, when the sample pipe support sampled reaches the front port of horizontal transfer slideway, horizontal transfer slideway starts, by The sample pipe support order of sampling is collected into horizontal transfer slideway, then by the sample pipe support sequentially-fed in horizontal transfer slideway Pipe support to longitudinal direction allotment slideway allocates mouth;
When being fully loaded with the sample pipe support sampled in Article 2 transverse direction transfer slideway, first horizontal transfer slideway starts, The follow-up sample pipe support sampled order is collected into first horizontal transfer slideway;
G, when the pipe support that sample pipe support reaches longitudinal direction allotment slideway allocates mouth, order longitudinal direction allotment slideway will be to be sampled Sample pipe support sequentially-fed slides the sample pipe support sequentially-fed sampled to longitudinal direction allotment to the input port of laterally input slideway The export section in road or the laterally input port of input slideway;
When longitudinally allotment slideway export section in be fully loaded with sample pipe support when, laterally input slideway start, by it is follow-up The sample pipe support order of sampling is collected into laterally in input slideway.
Another object of the present invention is realized by following technical proposals:A kind of full-automatic sampling device, there is a machine , automatic control circuit is installed, the right part of the support sets a laterally input slideway, the support on the support Left part sets a plurality of horizontal transfer slideway;The anterior of the support sets a longitudinal sample introduction slideway, on longitudinal sample introduction slideway A pipe support is set to be loaded into mouth and multiple pipe support diffluence pass;The rear portion of the support sets a longitudinal direction allotment slideway, the longitudinal direction Allocate slideway one end and importing section is set, its other end sets export section, and its middle part sets multiple pipe supports to allocate mouths and one Pipe support dispensing opening;The delivery outlet of the laterally input slideway is loaded into mouth with the pipe support of longitudinal sample introduction slideway and is connected, described Laterally the input port of input slideway is connected with the pipe support dispensing opening of the longitudinal direction allotment slideway;Before the horizontal transfer slideway Port is connected with the pipe support diffluence pass of longitudinal sample introduction slideway, and the rear port of the horizontal transfer slideway is adjusted with the longitudinal direction Pipe support allotment mouth with slideway is connected;The importing section installation sample tube identifier of the longitudinal direction allotment slideway;In the pipe Frame is loaded between mouth and the pipe support diffluence pass, is set sample tube mark scan device along longitudinal sample introduction slideway order, is added Sample needle device;The bottom setting conveying belt device of the laterally input slideway, the bottom setting of the horizontal transfer slideway are defeated Send belt dressing.
The present invention has the following advantages that compared with prior art:
1st, the present invention is scanned and identified to each sample pipe support, and the positional information of auto selecting swatches pipe support is as tune Foundation with sample pipe support, the Loading sequence of sample pipe support is reasonably controlled by Computer Control Technology, improve pattern detection Efficiency.
2nd, the present invention is by the use of horizontal transfer slideway as the buffering area for importing sample pipe support, by laterally input slideway and transverse direction Buffering area of the transfer slideway as output sample pipe support, takes full advantage of limited space, reduces the volume of sampling device.
3rd, full-automatic input mode of the invention, avoids operator from directly contacting and be contaminated with sample, greatly protection The health of operator, while it also avoid operator the accuracy of detection is influenceed on the pollution of sample.
The present invention is described in detail below in conjunction with the drawings and specific embodiments.
Brief description of the drawings
Fig. 1 is the structural representation of the full-automatic sampling device of the present invention;
Fig. 2 is Fig. 1 A-A sectional views;
Fig. 3 is the schematic diagram of the conveying belt device of the present invention;
Fig. 4 is the cross-sectional view of the horizontal input slideway of the present invention;
Fig. 5 is the schematic diagram of the Qian shape chute of the present invention;
Fig. 6 is the delivery device schematic diagram of the present invention;
Fig. 7 is the overlooking structure figure of sample pipe support;
Fig. 8 is the sample tube bit correction structure drawing of device of the present invention;
Fig. 9 is sample tube bit correction device overlooking structure figure;
Figure 10 is the distribution map of position sensor;
Figure 11 is the sample evenly mixing device structure chart of the present invention;
Figure 12 is the sample evenly mixing device overlooking structure figure of the present invention;
Figure 13 is the rollover states figure of sample evenly mixing device.
Embodiment
Embodiment one:
The sample injection method for being used for blood sample detection of the present invention, it is described full-automatic using a kind of full-automatic sampling device Sampling device includes one, and laterally input slideway, two horizontal transfer slideways, a longitudinal sample introduction slideway, a longitudinal direction allotment are slided Road, sets on longitudinal sample introduction slideway pipe support to be loaded into mouth and two pipe support diffluence pass, and the longitudinal direction allotment installation of slide track imports Section, export section, pipe support allotment mouth and pipe support dispensing opening;Sample tube identifier is set on the longitudinal direction allotment slideway, along institute State longitudinal sample introduction slideway order and sample tube mark scan device and sample-adding needle device are set;The detailed construction of full-automatic sampling device The disclosure of embodiment two is may refer to, operating procedure is:
Sample pipe support is sequentially placed into the importing section of longitudinal direction allotment slideway, full-automatic sampling device starts, and order is vertical A, Rear port to allotment slideway by sample pipe support sequentially-fed to the horizontal input port or horizontal transfer slideway for inputting slideway, sample This pipe identifier records the sample pipe support number of each sample tube and sample pore number and stored;
In the present embodiment, the importing section of the longitudinal direction allotment slideway is once put into 1 sample pipe support, and sample pipe support is pressed It is put into according to the sequencing of sampling;When detecting in the importing section there is sample pipe support, order longitudinal direction allotment slideway should at once The sample pipe support imported in section is sent out, with can be put into the 2nd sample pipe support.In the present embodiment, once can be continuous 31 sample pipe supports are put into, wherein, 10 sample pipe supports can be accommodated by laterally inputting in slideway, and two horizontal transfer slideways can be with 20 sample pipe supports are accommodated, 1 sample pipe support can be accommodated by importing in section.Allotment slideway conveying sample pipe support in longitudinal direction passes through sample During this pipe identifier, each sample tube on sample tube identifier scanned samples pipe support, sample pipe support number and sample pore are recorded Number send to computer installation store.Specifically, sample pipe support number is put into order for sample pipe support, from 1 to 31;Each sample Pipe support is provided with 6 sample pores, and the sample pore number of No. 1 sample pipe support is for the sample pore number of 1 to 6, No. 2 sample pipe supports 7 to 12;By that analogy.The position of each sample tube can be recorded by sample pipe support number and sample pore number.
B, when sample pipe support reaches the laterally input port of input slideway, laterally input slideway and start, sample pipe support is suitable Sequence is collected into laterally in input slideway;Then pipe support that sample pipe support is transported to longitudinal sample introduction slideway is loaded into mouth;In this implementation In example, the input port order of sample pipe support from laterally input slideway enters, and is laterally being promoted in a stepwise manner in input slideway.
When being laterally fully loaded with sample pipe support in input slideway, horizontal transfer slideway starts, by follow-up sample pipe support order It is collected into horizontal transfer slideway;When being fully loaded with sample pipe support in first horizontal transfer slideway, Article 2 transverse direction transfer slideway Start, follow-up sample pipe support order is collected into Article 2 transverse direction transfer slideway;
In the present embodiment, sample pipe support enters from the rear port order of horizontal transfer slideway, in horizontal transfer slideway Promote in a stepwise manner.Rear port of the sample pipe support being first put into away from horizontal transfer slideway, after the sample pipe support that is put into it is close The rear port of horizontal transfer slideway.Horizontal transfer slideway is to be counted from left to right, first horizontal transfer slideway and longitudinal direction It is adjacent to allocate the importing section of slideway, Article 2 transverse direction transfer slideway is adjacent with laterally input slideway.
C, when the pipe support that sample pipe support reaches longitudinal sample introduction slideway is loaded into mouth, longitudinal sample introduction slideway is ordered by sample pipe support To mark scan position, sample tube mark scan device starts sequentially-fed, each according to the sample pore journal Label information and storage in sample tube;Label information can be patient information, detection project information, detection ordering information etc., The label information of storage is used to provide examining report.
D, after the completion of mark scan, longitudinal sample introduction slideway is ordered by sample pipe support sequentially-fed to sample position, sample needle Device starts, and the blood sample in each sample tube is extracted according to the sample pore order;
In the present embodiment, sample tube is not stuck with sample pipe support sometimes, such as:Only in first sample of sample pipe support Sample tube is inserted with this pore and the 5th sample pore, then the sample pore number of computer installation storage is 1,5, sample needle dress Put after having extracted sample in first sample tube, order longitudinal sample introduction slideway that sample pipe support is pushed ahead into four step-lengths, directly The sample extracted in next sample tube is connect, improves sample introduction efficiency.
Sample-adding needle device is controlled by computer installation, and the sample of detection dosage is extracted from sample tube, is loaded needle device A sample is often extracted, carries out a cleaning operation.
E, after the completion of sampling, longitudinal sample introduction slideway is ordered by the sample pipe support sequentially-fed sampled to horizontal transfer slideway Front port;
F, when the sample pipe support sampled reaches the front port of horizontal transfer slideway, horizontal transfer slideway starts, by The sample pipe support order of sampling is collected into horizontal transfer slideway, then by the sample pipe support sequentially-fed in horizontal transfer slideway Pipe support to longitudinal direction allotment slideway allocates mouth;In the present embodiment, the sample pipe support exported out of horizontal transfer slideway is from transverse direction The front port of transfer slideway enters, and is promoted in a stepwise manner in horizontal transfer slideway.
When being fully loaded with the sample pipe support sampled in Article 2 transverse direction transfer slideway, first horizontal transfer slideway starts, The follow-up sample pipe support sampled order is collected into first horizontal transfer slideway;
In the present embodiment, always preferentially from longitudinal direction, allotment slideway collects sample pipe support to first horizontal transfer slideway, the Two horizontal transfer slideways always preferentially collect sample pipe support from longitudinal sample introduction slideway.
G, when the pipe support that sample pipe support reaches longitudinal direction allotment slideway allocates mouth, order longitudinal direction allotment slideway will be to be sampled Sample pipe support sequentially-fed slides the sample pipe support sequentially-fed sampled to longitudinal direction allotment to the input port of laterally input slideway The export section in road or the laterally input port of input slideway;
When longitudinally allotment slideway export section in be fully loaded with sample pipe support when, laterally input slideway start, by it is follow-up The sample pipe support order of sampling is collected into laterally in input slideway.
In the present embodiment, during the sample pipe support not being put into newly in the importing section of longitudinal direction allotment slideway, longitudinal direction allotment The unsampled sample pipe support that slideway collects horizontal transfer slideway is conveyed to laterally input slideway.
In the present embodiment, the sample pipe support sampled imports from the front port of horizontal transfer slideway, sample to be sampled Pipe support imports from the rear port of horizontal transfer slideway, and sample pipe support had both been probably to treat derived from the rear port of horizontal transfer slideway The sample pipe support of sampling, it is also possible to the sample pipe support sampled.
In the present embodiment, the export section once stores a sample pipe support, when the sample pipe support quilt of export section After taking away, slideway is allocated in longitudinal direction can just convey next sample pipe support sampled to export section.
The method of the present invention is controlled by the automatic control circuit provided with computer installation, by the position of sample pipe support And foundation of the status information as allotment sample pipe support, the automatic governing of sample pipe support sample introduction is realized, greatly improves clinic The test speed of inspection;Operating personnel is avoided because directly being contacted and contaminated risk with blood sample of patient, while also avoid Operator influences on the pollution of blood sample the accuracy of detection.
In the present embodiment, some detection projects need to carry out mixing processing to blood sample in advance, if blood sample Do not carried out mixing processing in sampling, or due to conveying the overlong time of sample pipe support, then need to be mixed before sampling Even processing, in the step C of aforesaid operations step, when the pipe support that sample pipe support reaches longitudinal sample introduction slideway is loaded into mouth, sample Evenly mixing device first starts, and mixes the blood sample in sample tube;Then, then order longitudinal sample introduction slideway that sample pipe support order is defeated Mark scan position is sent to, sample tube mark scan device starts, according to each sample tube of sample pore journal On label information and storage.
Embodiment two:
Referring to Fig. 1, Fig. 2, full-automatic sampling device of the invention, there is a support 1, automatic control is installed on the support Circuit processed, the right part of the support set a laterally input slideway 2, and the left part of the support sets two horizontal transfer slideways 3;The anterior of the support sets a longitudinal sample introduction slideway 4, sets a pipe support to be loaded into the He of mouth 41 on longitudinal sample introduction slideway Two pipe support diffluence pass 42,43;The rear portion of the support sets a longitudinal direction allotment slideway 5, and longitudinal direction allotment slideway left end is set Put and import section 51, right-hand member sets export section 52, and its middle part sets two pipe supports to allocate mouth 53,54 and a pipe support dispensing opening 55;The delivery outlet 22 of the laterally input slideway is loaded into mouth 41 with the pipe support of longitudinal sample introduction slideway and is connected, the transverse direction The input port 21 for inputting slideway is connected with the pipe support dispensing opening 55 of the longitudinal direction allotment slideway;Before the horizontal transfer slideway Port 31,32 is connected with the pipe support diffluence pass 42,43 of longitudinal sample introduction slideway, the rear port of the horizontal transfer slideway 33rd, 34 are connected with the pipe support allotment mouth 53,54 of the longitudinal direction allotment slideway;The importing section installation of the longitudinal direction allotment slideway Sample tube identifier 6;It is loaded into the pipe support between mouth 41 and the pipe support diffluence pass 42, along longitudinal sample introduction slideway order Sample tube mark scan device 7, sample-adding needle device 8 are set;The bottom of the laterally input slideway sets conveying belt device 26, The bottom of the horizontal transfer slideway sets conveying belt device 35.
Referring to Fig. 1, in the present embodiment, laterally input slideway 2 and longitudinal direction and allocate 5 orthogonal linking of slideway, sample pipe support from While opening dispensing opening 55, the input port 21 is directly entered;Laterally input slideway 2 and longitudinal 4 orthogonal rank of sample introduction slideway Connect, while sample pipe support leaves delivery outlet 22, be directly entered the pipe support and be loaded into mouth 41;Horizontal transfer slideway 3 is with indulging To the 4 orthogonal linking of sample introduction slideway, while sample pipe support leaves diffluence pass 42,43, be directly entered the front port 31, 32;Horizontal transfer slideway 3 allocates 5 orthogonal linking of slideway with longitudinal direction, while sample pipe support leaves rear port 33,34, directly Tap into the allotment mouth 53,54.
Referring to Fig. 4, Fig. 7, in the present embodiment, sample pipe support 10 is the plastic processing frame in in-line, sets six samples thereon This pore 101 and two hanging holes 102, the sample tube 11 of regular size is may be inserted into sample pore, each sample pore is just Face sets a scanning window 103, and sample tube mark scan device is through scanning window scanned samples pipe mark (such as bar code mark Note form, spraying mark etc. in sample tube).Sample pipe support both sides set chute 104, and the chute is with laterally inputting on slideway Horizontal slide rail coordinates.The bottom of sample pipe support sets three guiding grooves 105, the input port 21 of the guiding groove and laterally input slideway It is correspondingly arranged with three bootstrap blocks 23 of delivery outlet 22.
Referring to Fig. 1, Fig. 4, in the present embodiment, laterally input the both sides of slideway 2 and rib 24 is set, rib upper end is prolonged to inner side Stretching has horizontal slide rail 25, and the horizontal slide rail 25 matches with the chute 104 on sample pipe support, prevents sample pipe support from transversely inputting Slideway is toppled over when conveying.
Referring to Fig. 1, Fig. 3, in the present embodiment, the bottom for laterally inputting slideway 2 sets conveying belt device 26, the conveying Belt dressing includes the main synchronizing wheel of two stepper motors 262, two of conveyer belt 261, one 263, four from synchronizing wheel 264, institute The both ends for stating stepper motor are respectively provided with an output shaft, and two main synchronizing wheels are fixed on the output shaft of the stepper motor On, stepper motor and it is fixed on respectively by support on support from synchronizing wheel.Sample pipe support 10 is directly located in conveyer belt 261 On, in driving stepper motor lower conveyor belt conveying sample pipe support, transversely slide rail 25 is moved, and sample pipe support is sent into longitudinal sample introduction Slideway.Conveying belt device after a period of time is run, conveyer belt can loose skidding, by set tensioning wheel 265 regulation transmission The elasticity of band.
In the present embodiment, horizontal transfer slideway is identical with the structure of laterally input slideway, the structure of horizontal transfer slideway It refer to the structure description of laterally input slideway.
Referring to Fig. 1, Fig. 5, Fig. 6, in the present embodiment, slideway 5 is allocated in longitudinal direction includes a Qian shape chute 56, prevents sample Pipe support is toppled over when being conveyed along longitudinal direction allotment slideway.The side of longitudinal direction allotment slideway 5 sets delivery device, and delivery device is included laterally Guide rail mechanism, timing belt haulage gear, push support body 501, cross slide way mechanism is two guide pillars 502 be arrangeding in parallel, and this is led Post is arranged on support 1 by supporting plate 503, and push support body is provided with two slide openings, is slidably connected by the slide opening with guide pillar. Timing belt haulage gear by synchronous cog belt 504, stepper motor 505, main synchronizing wheel 506, form from synchronizing wheel 507, it is described to push away Send the afterbody of support body that elastic towing hook 508 is set.Stepper motor is fixed on support, and its output shaft is connected with main synchronizing wheel, main same Step wheel with being arranged on from synchronizing wheel by supporting plate 509 on support 1, with the synchronous cog belt fix by push support body bottom.Bullet Property towing hook afterbody be hinged with push support body, the middle part of elastic towing hook is connected by spring with pushing support body.Stepper motor can be with Driving push support body is moved back and forth along guide pillar, and sample pipe support is conveyed to the right by elastic towing hook.
In the present embodiment, longitudinal sample introduction slideway is identical with the structure of longitudinal direction allotment slideway, the side of longitudinal sample introduction slideway Identical delivery device also is provided with, the delivery device of longitudinal sample introduction slideway conveys sample pipe support to the left by elastic towing hook.
In the present embodiment, sample tube identifier is reflection optical coupler, and it is same as the prior art to be loaded the structure of needle device, can With with reference to the sample-adding needle device in Chinese patent 200920172819.0.Automatic control circuit includes computer installation, computer Installation matcher, automatic control circuit belong to routine techniques content, are not described in detail inside device.It is related in the present embodiment The position sensor of detection sample tube rack position belongs to routine techniques content, is not described in detail.
Referring to Figure 10, in the present embodiment, the importing section 51 that slideway is allocated in longitudinal direction sets first position sensor 57, horizontal Second place sensor 27 is set to the input port 21 of input slideway, the delivery outlet 22 for laterally inputting slideway sets the 3rd position to pass Sensor 28, the rear port 31,32 of horizontal transfer slideway set the 4th position sensor 36 and the 5th position sensor 37, in transverse direction The front port 33,34 for turning slideway sets the 6th position sensor 38 and the 7th position sensor 39, and the export of slideway is allocated in longitudinal direction Section 52 sets 8 positions sensor 58.Position sensor is used for the positional information of collecting sample pipe support, and position sensor will The positional information of sample pipe support is sent to computer installation, and computer installation is using the positional information of sample pipe support as allotment sample The foundation of pipe support, the state of sample pipe support can be determined according to the positional information of sample pipe support, laterally inputted in slideway and transverse direction Turn the quantity of sample pipe support in slideway, the state of sample pipe support, which is divided into, not to be sampled and sampled.
Referring to Fig. 1, in the present embodiment, sample tube mark scan device 7 can be conventional bar code scanner, It can be two-dimensional code scanning device.Mark letter in the sample tube that sample tube mark scan device is read through scanning window 103 Breath sends computer installation to, replaces corresponding sample pore number storage.When being scanned to sample tube mark, sample tube mark Note needs to be directed at scanning window, and sample pipe support is given a shock in course of conveying sometimes makes sample tube rotate, sample tube mark Note deviates scanning window.To solve this problem, in the indexing for being provided opposite to sample tube of the sample tube mark scan device Drive device 12, sample tube bit correction device can rotate sample tube one week, ensure that sample tube mark is scanned through window, also subtract Change operation of the operating personnel when inserting sample tube.
Referring to Fig. 1, Fig. 8, Fig. 9, in the present embodiment, described position shifter driving device 12 includes stepper motor 121, indexing Driving wheel, friction plate 123, the bottom surface of the support 1 are provided with two lower carriage plates, the shell of the stepper motor by bearing pin with Described two lower carriage plates are hinged, and the top of the indexable driving wheel is provided with wheel disc 122, and the bottom of the indexable driving wheel is provided with Wheel hub 124, the indexable driving wheel are fixedly mounted by the output shaft of the wheel hub and the stepper motor, the friction plate and institute Wheel hub friction is stated to set.
In the present embodiment, the lower carriage plate is provided with axis hole, and the both sides of the shell of stepper motor 121 are respectively provided with one Individual bearing pin, the bearing pin of stepper motor shell are inserted into the axis hole of lower carriage, and stepper motor can be swung around bearing pin.Indexing driving The wheel disc 122 of wheel is horizontally disposed, and wheel disc and the wheel hub of indexable driving wheel are integrally formed, using nylon or elastomeric material processing Into.
Referring to Fig. 8, in the present embodiment, the support is provided with bearing, and right-hand member and the bearing of the friction plate 123 are cut with scissors Connect, the left end of the friction plate is connected by spring 125 with the support 1.Cylindrical spring seat, spring one end set are set on support On the cylindrical spring seat, the other end is enclosed on the connecting hole of wearing piece.Wearing piece 123 can be with adjust automatically by spring 125 With the friction size on the surface of wheel hub 124, avoid stepper motor overload operation and damage.
In the present embodiment, wear rib is set between the friction plate and the wheel hub, and the wear rib is polytetrafluoroethyl-ne One kind in alkene wear rib, polyurethane wear resistant bar, rubber wear-resisting bar.Wear rib is fixed on the inside of wearing piece, and wear rib can subtract Slow abrasion of the wearing piece to wheel hub.
Referring to Fig. 8, Fig. 9, described position shifter driving device is arranged on support 1 with sample tube mark scan device 7, middle Longitudinal sample introduction slideway is set, and sample pipe support conveys along longitudinal sample introduction slideway, and multiple sample tubes 11 are inserted into the base of sample pipe support It is interior.Stepper motor 121 drives indexable driving wheel to rotate clockwise, and in the presence of wearing piece 123, promotes indexable driving wheel and step Stepper motor is overall to be deflected forward (in figure to the right) around bearing pin, and the wheel rim of wheel disc 122 is pressed in sample tube, and sample tube is in sample pipe support Base in rotate counterclockwise one week, sample tube mark is towards sample tube mark scan device, sample tube mark scan device note Record sample information.
Referring to Fig. 4, stepper motor 121 drives indexable driving wheel to rotate counterclockwise, and in the presence of wearing piece 123, promotes Indexable driving wheel deflects (in figure to the left) backward with stepper motor entirety around bearing pin, and sample pipe support pushes ahead a pipe position, weight Multiple above-mentioned steps, rotate next sample tube.
In the present embodiment, stepper motor is connected with an automatic control circuit, and automatic control circuit can be according to sample The signal enabling position shifter driving device that pipe mark scan device is sent.
Referring to Fig. 1, Figure 11, Figure 12, Figure 13, in the present embodiment, if the quantity of sample introduction sample is a lot, cause from sampling To the overlong time of sampling, sample needs mixing to be used to detect after handling.On described sample tube mark scan device 7 Trip, along described longitudinal sample introduction installation of slide track sample evenly mixing device 13.The sample evenly mixing device includes fulcrum bearing 131, described Fulcrum bearing is provided with axis hole, has a rotary shaft 133 to be arranged in the axis hole, and a rollover stand 132 is provided with the inside of the fulcrum bearing, The rear portion of the rollover stand is hinged with the rotary shaft;Pipe support hoisting mechanism, the pipe support elevator are set on the rollover stand Structure is made up of lifting frame body 134, synchronous cog belt 135, duplex belt pulley, driven pulley 137, upright guide rail 141, the lifting Support body is fixed with synchronous cog belt, and the duplex belt pulley is fixedly connected with the rotary shaft, big in the duplex belt pulley Gear 138 is connected with motor, and the little gear 136 in the duplex belt pulley is connected with the driven pulley, described The front portion of lifting frame body is provided with hook 142, and cover plate 140 is fixed with the top of the rollover stand.
In the present embodiment, the pipe support hoisting mechanism by lifting frame body 134, synchronous cog belt 135, duplex belt pulley, Two driven pulleys 137, upright guide rail 141 form.Upright guide rail is fixed on the both sides of rollover stand, and lifting frame body is slidably mounted on On upright guide rail.The duplex belt pulley is fixed in the rotary shaft, and duplex belt pulley is provided with gear wheel 138 and little gear 136, two driven pulleys are separately mounted to the front upper part and front lower portion of rollover stand, synchronous cog belt be centered around little gear with it is driven Between belt wheel, the shape of right angled triangle is formed.A motor, the power output belt of the motor are fixed in the fulcrum bearing bottom Wheel 139 is connected by belt and gear wheel.The driven pulley is gear, and power-take-off pulley is gear, and motor is Stepper motor.
Referring to Figure 11 to Figure 13, in the present embodiment, sample pipe support 10 is transported to sample and mixes dress by longitudinal sample introduction slideway The position put, driving stepper motor lifting frame body 134 move upwards along upright guide rail, right on the insertion sample of hook 142 pipe support 10 In the hanging hole 102 answered, lifting sample pipe support lives the mouth of pipe of sample tube 11 until cover plate for sealing, prevents blood sample from overflowing, at this moment Lifting frame body is integrally fixed with rollover stand and turned over around rotary shaft 133.Driving stepper motor lifting frame body is along upright guide rail Move downward, rollover stand overturns forward reset, and so on overturns and several times afterwards mixes the blood sample in sample tube, stepping electricity Machine driving lifting frame body moves downward along upright guide rail, links up with the hole exited on sample pipe support or groove, and release sample pipe support is to indulging To on sample introduction slideway.
In the present embodiment, stepper motor is connected with an automatic control circuit, and automatic control circuit is according to programme-control The rotation direction and stride of stepper motor.
In the present embodiment, it is necessary to which the blood sample mixed and the blood sample that need not be mixed use different types of sample This pipe dispenses, and the type classification of sample tube can be height difference or the color difference of pipe cap etc., and sample tube identifier will identify Data be supplied to automatic control circuit, automatic control circuit is handled the data of identification, is compared with material database, really Random sample this tubing type, only when the pipe support that the sample pipe support for needing to mix reaches longitudinal sample introduction slideway is loaded into mouth, start sample and mix Even device.

Claims (6)

  1. A kind of 1. sample injection method for blood sample detection, it is characterised in that:It is described complete using a kind of full-automatic sampling device Automatic sampling apparatus includes one and laterally inputs slideway, a plurality of horizontal transfer slideway, a longitudinal sample introduction slideway, a longitudinal direction tune Pipe support is set to be loaded into mouth and multiple pipe support diffluence pass, the longitudinal direction allotment installation of slide track with slideway, on longitudinal sample introduction slideway Import section, export section, pipe support allotment mouth and pipe support dispensing opening;Sample tube identifier is set on the longitudinal direction allotment slideway, Along longitudinal sample introduction slideway order, sample tube mark scan device and sample-adding needle device are set;Operating procedure is:
    Sample pipe support is sequentially placed into the importing section of longitudinal direction allotment slideway, full-automatic sampling device starts, and orders longitudinal direction to be adjusted A, Rear port with slideway by sample pipe support sequentially-fed to the horizontal input port or horizontal transfer slideway for inputting slideway, sample tube Identifier records the sample pipe support number of each sample tube and sample pore number and stored;
    B, when sample pipe support reaches the laterally input port of input slideway, laterally input slideway and start, sample pipe support order is received Collect laterally in input slideway;Then pipe support that sample pipe support is transported to longitudinal sample introduction slideway is loaded into mouth;
    When being laterally fully loaded with sample pipe support in input slideway, horizontal transfer slideway starts, and follow-up sample pipe support order is collected Into horizontal transfer slideway;When being fully loaded with sample pipe support in first horizontal transfer slideway, Article 2 transverse direction transfer slideway starts, Follow-up sample pipe support order is collected into Article 2 transverse direction transfer slideway;
    C, when the pipe support that sample pipe support reaches longitudinal sample introduction slideway is loaded into mouth, longitudinal sample introduction slideway is ordered by sample pipe support order Mark scan position is transported to, sample tube mark scan device starts, according to each sample of sample pore journal Label information and storage on pipe;
    D, after the completion of mark scan, longitudinal sample introduction slideway is ordered by sample pipe support sequentially-fed to sample position, sample-adding needle device Start, the blood sample in each sample tube is extracted according to the sample pore order;
    E, after the completion of sampling, longitudinal sample introduction slideway is ordered by before the sample pipe support sequentially-fed sampled to horizontal transfer slideway Port;
    F, when the sample pipe support sampled reaches the front port of horizontal transfer slideway, horizontal transfer slideway starts, and will sample Sample pipe support order be collected into horizontal transfer slideway, then by the sample pipe support sequentially-fed in horizontal transfer slideway to indulge Mouth is allocated to the pipe support of allotment slideway;
    When being fully loaded with the sample pipe support sampled in Article 2 transverse direction transfer slideway, first horizontal transfer slideway starts, by after The continuous sample pipe support sampled order is collected into first horizontal transfer slideway;
    G, when the pipe support that sample pipe support reaches longitudinal direction allotment slideway allocates mouth, longitudinal direction allotment slideway is ordered by sample to be sampled The sample pipe support sequentially-fed sampled is allocated slideway by pipe support sequentially-fed to the input port of laterally input slideway to longitudinal direction Export section or the laterally input port of input slideway;
    When being longitudinally fully loaded with sample pipe support in the export section of allotment slideway, laterally input slideway and start, by follow-up sampling Sample pipe support order be collected into laterally input slideway in.
  2. 2. sample injection method according to claim 1, it is characterised in that:In the step C of described operating procedure, work as sample When the pipe support that pipe support reaches longitudinal sample introduction slideway is loaded into mouth, sample evenly mixing device starts, and mixes the blood sample in sample tube;So Afterwards, longitudinal sample introduction slideway is ordered to start sample pipe support sequentially-fed to mark scan position, sample tube mark scan device, root According to the label information in each sample tube of sample pore journal and storage.
  3. 3. a kind of full-automatic sampling device, there is a support, automatic control circuit be installed on the support, it is characterised in that: The right part of the support sets a laterally input slideway, and the left part of the support sets a plurality of horizontal transfer slideway;The machine The anterior of seat sets a longitudinal sample introduction slideway, sets a pipe support to be loaded into mouth and the shunting of multiple pipe supports on longitudinal sample introduction slideway Mouthful;The rear portion of the support sets a longitudinal direction allotment slideway, and the longitudinal direction allotment slideway one end, which is set, imports section, its other end Export section is set, and its middle part sets multiple pipe support allotment mouths and a pipe support dispensing opening;The output of the laterally input slideway Mouth is connected with the pipe support loading mouth of longitudinal sample introduction slideway, input port and the longitudinal allotment of the laterally input slideway The pipe support dispensing opening of slideway is connected;The pipe support diffluence pass of the front port of the horizontal transfer slideway and longitudinal sample introduction slideway It is connected, the rear port of the horizontal transfer slideway is connected with the pipe support allotment mouth of the longitudinal direction allotment slideway;The longitudinal direction Allocate the importing section installation sample tube identifier of slideway;It is loaded into the pipe support between mouth and the pipe support diffluence pass, along institute State longitudinal sample introduction slideway order and sample tube mark scan device, sample-adding needle device are set;The bottom of the laterally input slideway is set Conveying belt device is put, the bottom of the horizontal transfer slideway sets conveying belt device.
  4. 4. full-automatic sampling device according to claim 3, it is characterised in that:On the sample tube mark scan device Trip, along described longitudinal sample introduction installation of slide track sample evenly mixing device.
  5. 5. full-automatic sampling device according to claim 4, it is characterised in that:The sample evenly mixing device includes supporting Seat, the fulcrum bearing are provided with axis hole, have a rotary shaft to be arranged in the axis hole, and a upset is provided with the inside of the fulcrum bearing Frame, the rear portion of the rollover stand are hinged with the rotary shaft;Pipe support hoisting mechanism, the pipe support lifting are set on the rollover stand Mechanism is made up of lifting frame body, synchronous cog belt, duplex belt pulley, driven pulley, upright guide rail, the lifting frame body with it is synchronous Cog belt is fixed, and the duplex belt pulley is fixedly connected with the rotary shaft, gear wheel and motor in the duplex belt pulley It is connected, the little gear in the duplex belt pulley is connected with the driven pulley, and the front portion of the lifting frame body is set There is hook, cover plate is fixed with the top of the rollover stand.
  6. 6. full-automatic sampling device according to claim 5, it is characterised in that:Pair of the sample tube mark scan device Face sets the position shifter driving device of sample tube, and described position shifter driving device includes stepper motor, indexable driving wheel, friction plate, The bottom surface of the support is provided with two lower carriage plates, and the shell of the stepper motor is cut with scissors by bearing pin and described two lower carriage plates Connect, the top of the indexable driving wheel is provided with wheel disc, and the bottom of the indexable driving wheel is provided with wheel hub, and the indexable driving wheel leads to The output shaft for crossing the wheel hub and the stepper motor is fixedly mounted, and the friction plate is set with wheel hub friction.
CN201610281615.5A 2016-05-03 2016-05-03 A kind of sample injection method and device for blood sample detection Pending CN107340400A (en)

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Application publication date: 20171110