CN107303248A - A kind of compound Artemisia rupestris sterilizes gargle - Google Patents
A kind of compound Artemisia rupestris sterilizes gargle Download PDFInfo
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- CN107303248A CN107303248A CN201610248294.9A CN201610248294A CN107303248A CN 107303248 A CN107303248 A CN 107303248A CN 201610248294 A CN201610248294 A CN 201610248294A CN 107303248 A CN107303248 A CN 107303248A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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Abstract
Gargle is sterilized the invention discloses a kind of compound Artemisia rupestris, it is a kind of effect type Chinese herbal medicine sterilization gargle, the gargle, which has, to be killed oral bacteria, removes halitosis, anti-treating dental ulcer and the effect having sore throat, the characteristics of with without essence, pigment, it can be also used for artificial tooth immersion and sterilizing.Refrigerant tasty and refreshing of the present invention, natural Chinese medicinal herb plant fragrance taste is left using rear breath freshening, aftertaste.The present invention is to the addition of the Chinese herbal medicine extract with efficacy active component in the liquid-based for prepare gargle to include：The careless extract of Herba Achilleae extract, agastache extract, Notogineng Extract, Folium Et Cacumen Murrayae extract, Herba Scutellariae Barbatae extract, phoenix neck, gargle is made in this six kinds of Chinese herbal medicine extracts and gargle liquid-based reasonable compatibility, it is to nurse one of tooth and the preferable ancillary drug gargle of mouth disease, even more very popular product.
Description
Technical field
A kind of compound Artemisia rupestris sterilization gargle of the present invention, is to belong to daily-use chemical industry oral-cavity article field, is related to a kind of plant fragrance type Chinese herbal medicine gargle.The gargle is included by efficacy active component Chinese herbal medicine extract：The careless extract of Herba Achilleae extract, agastache extract, Notogineng Extract, Folium Et Cacumen Murrayae extract, Herba Scutellariae Barbatae extract, phoenix neck, this six kinds of Chinese herbal medicine extracts are formed with gargle liquid-based and deionized water mixed preparing.This six kinds there is efficacy active component Chinese herbal medicine extract to be added in gargle liquid-based by the present invention first, it can reach the effect of prevention or treatment tooth and mouth disease, with anti-inflammation hemostasia, swelling and pain relieving, sterilization of relieving inflammation or internal heat, dispel halitosis, anti-treating dental ulcer and the effect having sore throat, the characteristics of with without essence pigment, it is the innovative product in oral-cavity article field, is effect type Chinese herbal medicine sterilization gargle.
Background technology
With the continuous development of scientific technology with the continuous improvement of living standards of the people, the yield and sales volume of various gargles are only second to toothpaste, and second, the gargle number in the majority of wherein fluoride are accounted in dental care product.A kind of compound Artemisia rupestris sterilization gargle of the present invention is effect type Chinese herbal medicine gargle, is included containing six kinds of Chinese herbal medicine extracts：This six kinds of Chinese herbal medicine extracts of the careless extract of Herba Achilleae extract, agastache extract, Notogineng Extract, Folium Et Cacumen Murrayae extract, Herba Scutellariae Barbatae extract, phoenix neck.Recorded according to traditional Chinese medical science pharmacopeia：Alpine yallow herb has clearing heat and detoxicating, anti-inflammatory analgetic effect；Wrinkled giant hyssop, which has, eliminates dampness with aromatics and middle preventing or arresting vomiting, delivers relieving summer-heat, sterilization, the effect except halitosis；Pseudo-ginseng has hemostasis, dissipates the stasis of blood, the effect of detumescence ding-tong；Kamuning has analgesic, detumescence, the effect for the treatment of toothache；Sculellaria barbata has heat-clearing, dissipates the stasis of blood, hemostasis, analgesic therapy, controls and has sore throat；Phoenix neck grass has clearing heat and detoxicating, invigorating circulation of blood to dissipate blood stasis and reducing swelling and relieving pain, controls diphtheria, noma.The present invention is according to theory of traditional Chinese medical science, reasonable compatibility, this six kinds of Chinese herbal medicine extracts are applied in formula of liquid of gargling first gargle is made, anti-inflammatory analgetic, detumescence hemostasis, sterilization of relieving inflammation or internal heat can be played a part of, halitosis, anti-treating dental ulcer is dispelled and have sore throat, it can also prevent or treat odontopathy, be effect type Chinese herbal medicine gargle that consumer expects.Because gargle is liquid, it need not be brushed teeth when gargling, therefore, the injury in the absence of rubbing agent or toothbrush to periodontal, the crowd for being inconvenient to brush teeth for the children and adolescents in the period of growing, pregnant woman, old man, out of town trip person, field worker etc. is more applicable.
The content of the invention
Gargle is sterilized the invention discloses a kind of compound Artemisia rupestris, the gargle is by Herba Achilleae extract, agastache extract, Notogineng Extract, Folium Et Cacumen Murrayae extract, Herba Scutellariae Barbatae extract, the careless extract of phoenix neck, this six kinds of Chinese herbal medicine extracts are added in gargle liquid-based and deionized water mixed preparing is formed, it is used conveniently and safely, bactericidal effect is notable.
A kind of compound Artemisia rupestris sterilization gargle of the present invention, the Herba Achilleae extract is the xeraphium of alpine yallow herb ethanol extract, agastache extract is the xeraphium of wrinkled giant hyssop ethanol extract, Notogineng Extract is the xeraphium of pseudo-ginseng ethanol extract, Folium Et Cacumen Murrayae extract is the xeraphium of kamuning ethanol extract, Herba Scutellariae Barbatae extract is the xeraphium of Sculellaria barbata ethanol extract, and phoenix neck grass extract is the xeraphium of the careless ethanol extract of phoenix neck.
A kind of compound Artemisia rupestris sterilization gargle of the present invention, the Herba Achilleae extract, agastache extract, Notogineng Extract, Folium Et Cacumen Murrayae extract, Herba Scutellariae Barbatae extract, phoenix neck grass extract, this six kinds of Chinese herbal medicine extracts are not limited to such as the xeraphium of alpine yallow herb ethanol extract, it also can use supercritical extract, ultrasonic extraction thing, extract solution, medicinal extract extract, crushed material, existing commercially available Chinese medical extract can also be used, if be applied to other forms such as extract solution or medicinal extract in gargle, addition in formula should be converted to disclosed in this invention formula in extract addition.
Liquid-based in a kind of compound Artemisia rupestris sterilization gargle of the present invention includes.
Efficacy active component Chinese herbal medicine extract includes：Herba Achilleae extract, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 30%；Agastache extract, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 20%；Notogineng Extract, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 20%；Folium Et Cacumen Murrayae extract, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 20%；Herba Scutellariae Barbatae extract, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 20%；Phoenix neck grass extract, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 20%.
Edible ethanol, the percentage by weight accounted in gargle liquid-based is 5% ~ 25%.
NMF, the percentage by weight accounted in gargle liquid-based is 5% ~ 35%, can select one kind or and combinations thereof in glycerine, propane diols, sorbierite.
Aromatic, the percentage by weight accounted in gargle liquid-based is 0.5% ~ 2%, can select one kind or and combinations thereof in spearmint oil, peppermint oil, caryophyllus oil, fennel oil, cinnamon oil, orange oil, Lavender, Pogostemon cablin essential.
Surfactant, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 2%, can select laruyl alcohol sodium sulfovinate, sodium N-lauroyl sarcosinate.
Sweetener, the percentage by weight accounted in gargle liquid-based is 0.01% ~ 2%, can select one kind or and combinations thereof in saccharin sodium, Aspartame, honey element.
Solubilizer, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 2%, can select Tween-20, Tween-80, one kind in PEG-40 rilanit specials or and combinations thereof.
Preservative, the percentage by weight accounted in gargle liquid-based is 0.05% ~ 0.5%, can select one kind or and combinations thereof in methyl hydroxybenzoate, ethylparaben, propylben, sodium benzoate.
Stabilizer, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 0.5%, can select one kind or combinations thereof in sodium dihydrogen phosphate, tetrasodium pyrophosphate.
Surplus is deionized water.
The characteristics of a kind of compound Artemisia rupestris sterilization gargle of the present invention has without essence, pigment, with natural Chinese medicinal herb stoste true qualities and the characteristics of natural plants fragranced, this product refrigerant tasty and refreshing, using rear breath freshening and the fragranceds of natural plants is left, be a kind of natural plants effect type Chinese herbal medicine sterilization gargle.
Embodiment.
The present invention is described in further detail below by specific embodiment, following examples are descriptive, is not limited, it is impossible to which protection scope of the present invention is limited with this.
A kind of compound Artemisia rupestris sterilization gargle of the present invention, preparation technology is to add aromatic in edible ethanol to dissolve to obtain A liquid, Chinese herbal medicine extract is added and is uniformly dissolved in deionized water, NMF, solubilizer is sequentially added to stir to abundant dissolving, add sweetener, preservative, stabilizer, surfactant and B liquid is mixed evenly to obtain, while A liquid is slowly added to fully to dissolve in B liquid, stand, filtering, produces compound Artemisia rupestris sterilization gargle after the assay was approved.
A kind of compound Artemisia rupestris sterilization gargle constitutive material is weight percent content in 1-3 examples below.
Example 1：
Formula：Edible ethanol 5, glycerine 10, PEG-40 rilanit specials 1.5, saccharin sodium 0.1, Herba Achilleae extract 1, agastache extract 0.2, Notogineng Extract 0.2, Folium Et Cacumen Murrayae extract 0.2, the careless extract 0.2 of Herba Scutellariae Barbatae extract 0.2, phoenix neck, sodium benzoate 0.05, menthol 0.5, sodium dihydrogen phosphate 0.1, deionized water（Surplus）Composition；
Preparation method：Menthol is added in edible ethanol by the content and component and dissolves to obtain A liquid, said herbal medicine extract is added and is uniformly dissolved in deionized water, glycerine, PEG-40 rilanit specials is sequentially added to stir to abundant dissolving, add saccharin sodium, sodium benzoate, sodium dihydrogen phosphate and B liquid is mixed evenly to obtain, simultaneously A liquid is slowly added to fully to dissolve in B liquid, stand, filtering, compound Artemisia rupestris sterilization gargle is produced after the assay was approved.
Example 2：
Formula：Edible ethanol 10, sorbierite 20, PEG-40 rilanit specials 0.8, saccharin sodium 0.01, Herba Achilleae extract 2, agastache extract 2, Notogineng Extract 0.5, Folium Et Cacumen Murrayae extract 1, the careless extract 1.5 of Herba Scutellariae Barbatae extract 1, phoenix neck, ethylparaben 0.15, menthol 0.6, tetrasodium pyrophosphate 0.15, deionized water（Surplus）Composition；
Preparation method：Menthol is added in edible ethanol by the content and component and dissolves to obtain A liquid, said herbal medicine extract is added and is uniformly dissolved in deionized water, sorbierite, PEG-40 rilanit specials is sequentially added to stir to abundant dissolving, add saccharin sodium, ethylparaben, tetrasodium pyrophosphate and B liquid is mixed evenly to obtain, simultaneously A liquid is slowly added to fully to dissolve in B liquid, stand, filtering, compound Artemisia rupestris sterilization gargle is produced after the assay was approved.
Example 3：
Formula：Edible ethanol 15, sorbierite 10, glycerine 5, tween -80 2, saccharin sodium 0.05, Herba Achilleae extract 5, agastache extract 3, Notogineng Extract 1, Folium Et Cacumen Murrayae extract 2, the careless extract 2 of Herba Scutellariae Barbatae extract 3, phoenix neck, methyl hydroxybenzoate 0.1, menthol 0.5, tetrasodium pyrophosphate 0.1, laruyl alcohol sodium sulfovinate 0.1, deionized water（Surplus）Composition；
Preparation method：Menthol is added in edible ethanol by the content and component and dissolves to obtain A liquid, said herbal medicine extract is added and is uniformly dissolved in deionized water, the stirring of sorbierite, glycerine, tween -80 is sequentially added to abundant dissolving, add saccharin sodium, methyl hydroxybenzoate, tetrasodium pyrophosphate, laruyl alcohol sodium sulfovinate and B liquid is mixed evenly to obtain, simultaneously A liquid is slowly added to fully to dissolve in B liquid, stand, filtering, compound Artemisia rupestris sterilization gargle is produced after the assay was approved.
The invention is not limited in above-mentioned embodiment; anyone should learn the dosage or formula made under the enlightenment of the present invention; be also that those skilled in the art obviously change, it is every with it is of the invention have it is same or similar as technical scheme formula, belong in protection scope of the present invention.
Claims (5)
1. a kind of compound Artemisia rupestris sterilizes gargle, the gargle is included by efficacy active component Chinese herbal medicine extract：The careless extract of Herba Achilleae extract, agastache extract, Notogineng Extract, Folium Et Cacumen Murrayae extract, Herba Scutellariae Barbatae extract, phoenix neck, edible ethanol, NMF, aromatic, surfactant, sweetener, solubilizer, preservative, stabilizer and deionized water composition.
2. a kind of compound Artemisia rupestris of the invention sterilizes gargle according to claim 1, it is characterised in that：The Herba Achilleae extract is the xeraphium of alpine yallow herb ethanol extract, agastache extract is the xeraphium of wrinkled giant hyssop ethanol extract, Notogineng Extract is the xeraphium of pseudo-ginseng ethanol extract, Folium Et Cacumen Murrayae extract is the xeraphium of kamuning ethanol extract, Herba Scutellariae Barbatae extract is the xeraphium of Sculellaria barbata ethanol extract, phoenix neck grass extract is the xeraphium of the careless ethanol extract of phoenix neck, this six kinds of Chinese herbal medicine extracts have anti-inflammatory analgetic, detumescence hemostasis, sterilization, dispel halitosis, anti- treating dental ulcer and the effect having sore throat, the characteristics of with refrigerant tasty and refreshing, add it in gargle, it is safely and effectively effect type Chinese herbal medicine sterilization gargle.
3. a kind of compound Artemisia rupestris of the invention sterilizes gargle according to claim 1, it is characterised in that：The gargle liquid-based includes：
Efficacy active component Chinese herbal medicine extract includes：Herba Achilleae extract, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 30%；Agastache extract, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 20%；Notogineng Extract, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 20%；Folium Et Cacumen Murrayae extract, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 20%；Herba Scutellariae Barbatae extract, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 20%；Phoenix neck grass extract, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 20%；
Edible ethanol, the percentage by weight accounted in gargle liquid-based is 5% ~ 25%；
NMF, the percentage by weight accounted in gargle liquid-based is 5% ~ 35%, can select one kind or and combinations thereof in glycerine, propane diols, sorbierite；
Aromatic, the percentage by weight accounted in gargle liquid-based is 0.5% ~ 2%, can select one kind or and combinations thereof in spearmint oil, peppermint oil, caryophyllus oil, fennel oil, cinnamon oil, orange oil, Lavender, Pogostemon cablin essential；
Surfactant, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 2%, be can select from laruyl alcohol sodium sulfovinate, sodium N-lauroyl sarcosinate；
Sweetener, the percentage by weight accounted in gargle liquid-based is 0.01% ~ 2%, can select one kind or and combinations thereof in saccharin sodium, Aspartame, honey element；
Solubilizer, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 2%, can select Tween-20, Tween-80, one kind in PEG-40 rilanit specials or and combinations thereof；
Preservative, the percentage by weight accounted in gargle liquid-based is 0.05% ~ 0.5%, can select one kind or and combinations thereof in methyl hydroxybenzoate, ethylparaben, propylben, sodium benzoate；
Stabilizer, the percentage by weight accounted in gargle liquid-based is 0.1% ~ 0.5%, can select one kind or combinations thereof in sodium dihydrogen phosphate, tetrasodium pyrophosphate；
Surplus is deionized water.
4. a kind of compound Artemisia rupestris of the invention sterilizes gargle according to claim 1, it is characterised in that：The careless extract of the Herba Achilleae extract, agastache extract, Notogineng Extract, Folium Et Cacumen Murrayae extract, Herba Scutellariae Barbatae extract, phoenix neck, this six kinds of Chinese herbal medicine extracts are not limited to such as the xeraphium of alpine yallow herb ethanol extract, it also can use supercritical extract, ultrasonic extraction thing, extract solution, medicinal extract extract, crushed material, existing commercially available Chinese medical extract can also be used, if be applied to other forms such as extract solution or medicinal extract in gargle, the addition in formula should be converted to disclosed in this invention formula in extract addition.
5. a kind of compound Artemisia rupestris of the invention sterilizes gargle according to claim 1, it is characterised in that：Without essence, pigment in gargle, this product compound Artemisia rupestris sterilization gargle has natural plants fragranced and taste of traditional Chinese medicine, and the stoste true qualities with natural Chinese medicinal herb have no side effect, and is natural plants effect type Chinese herbal medicine sterilization gargle.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111096936A (en) * | 2019-12-30 | 2020-05-05 | 柳州两面针股份有限公司 | Application of sculellaria barbata extract in preparation of oral care products |
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| CN103655301A (en) * | 2013-11-26 | 2014-03-26 | 乌鲁木齐一枝好生物科技有限公司 | Tooth paste containing artemisia rupestris extract and preparation method thereof |
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2016
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1927160A (en) * | 2006-08-25 | 2007-03-14 | 青岛大学医学院附属医院 | Gargle and its preparing process |
| EP2262821A2 (en) * | 2008-04-11 | 2010-12-22 | Institut de Recherche pour le Développement ( IRD) | Process for the extraction of mangiferin and isomangiferin |
| CN103263375A (en) * | 2013-05-30 | 2013-08-28 | 云南七丹药业股份有限公司 | Mouthrinse containing extract and preparation method of mouthrinse |
| CN103655301A (en) * | 2013-11-26 | 2014-03-26 | 乌鲁木齐一枝好生物科技有限公司 | Tooth paste containing artemisia rupestris extract and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111096936A (en) * | 2019-12-30 | 2020-05-05 | 柳州两面针股份有限公司 | Application of sculellaria barbata extract in preparation of oral care products |
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Application publication date: 20171031 |