CN104473822A - Mouthwash tablet containing plant extract and preparation method of mouthwash tablet - Google Patents
Mouthwash tablet containing plant extract and preparation method of mouthwash tablet Download PDFInfo
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- CN104473822A CN104473822A CN201410716890.6A CN201410716890A CN104473822A CN 104473822 A CN104473822 A CN 104473822A CN 201410716890 A CN201410716890 A CN 201410716890A CN 104473822 A CN104473822 A CN 104473822A
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Abstract
The invention provides a mouthwash tablet containing a plant extract. In term of the dry weight of a finished product, the mouthwash tablet consists of the following components in percentage by weight: 8-15% of a natural plant extract, 20-40% of a film forming agent, 10-25% of an abrasive agent, 4-16% of edible essence, 5-10% of an emulsifying agent, 2-10% of a foaming cleanser, 15-25% of a thickening agent, 1-3% of a bacteriostat and 1-3% of a sweetening agent. The preparation method of the mouthwash tablet comprises the following steps: mixing and stirring the components so as to obtain gel, preparing the gel into a thin film and slicing the thin film to obtain the mouthwash tablet; the mouthwash tablet can be rapidly dissolved in water to form mouthwash liquid, and the mouthwash liquid can be directly used for washing mouth so as to clean and care the oral cavity and to achieve the effects of cleaning teeth, freshening breath and killing bacteria; and meanwhile, the mouthwash tablet can be used as an article for daily oral cavity cleaning and caring.
Description
Technical field
The present invention relates to oral care implement field, be specifically related to a kind of containing plant extract gargle tablet and preparation method thereof.
Background technology
The tooth of the beautiful brilliant white of a bite can add much beauty to for personal image, but odontopathy also annoyings many people, particularly dental caries has had a strong impact on the image of people, social activity and healthy.
Multiple help user is had now to carry out the product of oral cavity health on the market, common are the products such as toothpaste, chewing gum, collutory, flavorants, can cleaning teeth be passed through, eliminate the mode such as implication, kill bacteria, positive treatment and health-care effect are played to oral cavity health.
But above product also has certain defect, toothpaste be a kind of use the most extensive, the tooth cleaning product that cleaning efficiency is best, but its to there is volume excessive, carry the problem of inconvenience; Chewing gum energy cleaning teeth eliminates implication cleaning teeth, but its to tooth antibacterial without killing effect; Flavorants has antibacterial type and non-antibacterial type, can clean implication, but cannot carry out effective cleaning to tooth; Collutory is easy to carry, can cleaning teeth, eliminate implication, kill bacteria, use extensively, but the collutory of liquid state is once leak and may soak other important items, causes irretrievable loss.
In view of this, have producer start to research and develop and produce gargle tablet on the market, its cleaning teeth, eliminate implication, kill the function carefully possessed, and be convenient for carrying, solid, shaped avoids the possibility of leaking and soaking other article.
CN200710032657 provides a kind of gargle tablet and preparation method thereof, in solid sheet, it is entrance decentralized oral care product, it contains film former, freshener, emulsifying agent, foam cleaners and abrasivus, this solid gargle tablet can provide antibacterial simultaneously, cleaning oral cavity, removal implication, the effects such as caries prevention, and easy to carry, use easily.But the occupation mode of the gargle tablet of this inlet type dispersibility is gargled containing clear water into gargle tablet by containing again, this gargle tablet contains more foam cleaners, film former, they can absorb rapidly the moisture in oral cavity, it can be that oral cavity becomes dry the short time, even destroy the mucosa in oral cavity, plasticizer too much in addition also can cause the Liver and kidney of people, reproductive function causes damage, has mutagenesis and carcinogenecity.
CN201010220670 provides one containing nysfungin mouthwash formulation, and it can make the preparation of the forms such as gargle tablet, effervescent tablet, dispersible tablet, granule, buccal tablet, and the nysfungin composition contained is for prevention and treatment buccal cavity fungal infection.The nysfungin that said preparation adopts is a kind of broad-spectrum antifungal medicine, and its product function is mainly as pharmaceutical products, makes for buccal cavity fungal infection, and daily life-time service can make flora in oral cavity unbalance, not can be used as common oral cleaning-nursing and uses.
CN200810103364 provides one to have synergistic nysfungin menthol compositions, its most preferably mode making dosage form is gargle tablet, the nysfungin composition contained, for prevention and treatment buccal cavity fungal infection, can obtain good synergistic therapeutic effect with configuring in proportion of menthol.But same, the major function of said preparation is as pharmaceutical products, and broad-spectrum antifungal medicine nysfungin makes these product not be suitable for common oral cleaning-nursing.
CN200580048793 provides a kind of extract of magnolia that uses and reduces the method for oral tissue inflammation, utilizes the natural anti-inflammatory active ingredient of Drymotaenium miyoshianum (Mak.) Mak. to reduce one or more checking mediators and the inflammation that reduces in oral cavity tissue.The natural anti-inflammatory active ingredient safety of extract of magnolia, effectively and nonirritant.Said composition can produce the forms such as toothpaste, gel, powder, lozenge, but does not provide the method specifically making portability cleaning oral cavity product.
CN95104632.2 provides a kind of gargle made of sarcandra glabra, by prefabricated Herba Pileae Scriptae extracting solution, after again natural menthence, tween 80,95% edible ethanol, medicinal glycerin being mixed containing part by weight, add Herba Pileae Scriptae extracting solution, additives and distilled water and stir obtained collutory.This product is liquid condition and not portable equally.
Summary of the invention
The invention provides a kind of containing plant extract gargle tablet and preparation method thereof, dissolve rapidly by steeping after in water, form collutory, then directly carry out with this collutory the cleaning-nursing gargling to obtain oral cavity, reach cleaning teeth, eliminate the effect of implication, kill bacteria, this gargle tablet can use as common oral cleaning nursing article simultaneously.
For achieving the above object, the present invention adopts following technological means, and concrete steps are as follows:
Containing plant extract gargle tablet, its form is chip solid, is to turn to collutory by being dissolved in the water to use.As follows by the percentage by weight of each component of finished product dry weight:
Natural plant extracts 8-15%
Film former 20-40%
Abrasivus 10-25%
Edible essence 4-16%
Emulsifying agent 5-10%
Foam cleaners 2-10%
Thickening agent 15-25%
Antibacterial 1 ~ 3%
Sweeting agent 1 ~ 3%
Described natural plant extracts is that pulverous Herba Pileae Scriptae extract and pulverous extract of magnolia mix in the ratio of 5 ~ 10:3 ~ 5;
Preferably, in Herba Pileae Scriptae extract, sterling content is 25 ~ 50%, and in extract of magnolia, sterling content is 25 ~ 50%.
Described film former can be one or more and chitosan in carboxymethyl cellulose, hydroxyethyl-cellulose, hydroxypropyl cellulose, one or more in sodium alginate, modified starch, Pullulan, maltodextrin, guar gum, konjaku powder are mixed.
Preferably, film former selects that carboxymethyl cellulose, hydroxyethyl-cellulose, hydroxypropyl cellulose take weight ratio as 1:2:3 and chitosan, one or more in sodium alginate, modified starch, Pullulan, maltodextrin, guar gum, konjaku powder are mixed.
Preferred, membrane selects carboxymethyl cellulose, hydroxyethyl-cellulose, hydroxypropyl cellulose to take weight ratio as 1:2:3 and chitosan, Pullulan, maltodextrin with weight ratio to be the ratio mixing of 1:1:1 obtained.
Described abrasivus is that the mixing of 1:5:4 ratio is obtained with weight ratio by silicon dioxide, calcium bicarbonate and calcium carbonate.
Described edible essence is bamboo essence and can menthol, is that the ratio mixing of 2:1 is obtained by bamboo essence and menthol with weight ratio.
The ratio mixing that described emulsifying agent is crosslinked carboxylic first first Starch Sodium, poloxamer, glyceryl stearate take weight ratio as 1:2:2 is obtained.
Described foam cleaners can select one or more mixing in lauryl triethanolamine sodium sulfate, sodium lauroyl sarcosine, sodium lauryl sulphate, laurylglutamic sodium obtained.
Preferably, described foam cleaners selection lauryl triethanolamine sodium sulfate, sodium lauryl sulphate, laurylglutamic sodium are that the ratio mixing of 1:3:2 is obtained with weight ratio.
The form mixing of described thickening agent to be cyclodextrin and betacyclodextrin with weight ratio be 1:3 is obtained.
Described antibacterial is chlorhexidine acetate, benzalkonium bromide, 2,4, and one or more in 4 '-trichlorine, 2 '-dihydroxy diphenyl ether, first nitre file, cetylpyridinium chloride are mixed.
Preferably, the chlorhexidine acetate selected, 2,4 of described antibacterial, 4 '-trichlorine, 2 '-dihydroxy diphenyl ether and cetylpyridinium chloride mix with the ratio of 1:1:1.
Described sweeting agent is obtained with the mixing of the ratio of 3:1 by xylitol and sucralose.
Present invention also offers a kind of containing plant extract gargle tablet and preparation method thereof, made by following steps:
Step 1: film former is joined in deionized water, both weight ratios are 1:3, heat while stirring, and limit adds above-mentioned abrasivus, emulsifying agent, foam cleaners, thickening agent, mixing speed is set to 500r/min, when above mixture heat up 65 DEG C time add edible essence, antibacterial, sweeting agent, continue to keep this heating-up temperature, regulate mixing speed to be that 800r/min stirs 0.5h, then add natural plant extracts after being cooled to 45 DEG C, stir and form rubber cement after 0.5 hour;
Step 2: the rubber cement of gained in step 1 is made thin film, and ensure that it is by certain thickness;
Step 3: by the thin film evaporate to dryness film forming of gained in step 2, ensures that its moisture is 15% ~ 18%, after cooling section obtain described in containing plant extract gargle tablet.
Preferably, cooled thin film is cut into the section of 50mm × 40mm × 0.2mm.
Usefulness of the present invention is, natural plant extracts is added in gargle tablet, anti-inflammatory analgesic, antibacterial, pure white effect is possessed in the function of the heat-clearing and toxic substances removing utilizing Herba Pileae Scriptae extract to possess, reducing swelling and alleviating pain, anti-inflammation and extract of magnolia, the antibacterial of other synthetic relative, analgesic composition, whitening agent, have higher safety, employing natural plant extracts can reduce the stimulation to oral cavity simultaneously.
Select do not cover the bamboo essence of natural plant extracts abnormal smells from the patient and the menthol of clean mouthfeel can be provided simultaneously, and add xylitol and the sucralose of the palatability improving this product, make product provide nature, salubrious mouthfeel.
Adding described foam cleaners can be to form abundant foam gargling, can emulsifying and the spot removed in oral cavity, strengthens the cleaning capacity of this product.
Detailed description of the invention
The invention discloses a kind of containing plant extract gargle tablet and preparation method thereof, those skilled in the art can use for reference present disclosure, and appropriate reconstruction technological parameter realizes the making of this product.Special needs to be pointed out is, all similar replacements and change apparent to those skilled in the art, they are deemed to be included in the present invention.Of the present inventionly have passed through preferred embodiment containing plant extract gargle tablet and preparation method thereof and be described, related personnel obviously can not depart from content of the present invention, spirit and scope methods and applications as herein described are changed or suitably change with combination, realize and apply the technology of the present invention.
If no special instructions, the test material related in a specific embodiment all freely can be buied from market.
Embodiment 1
Containing plant extract gargle tablet, as follows by the percentage by weight of each component of finished product dry weight:
Natural plant extracts 12%
Film former 40%
Abrasivus 10%
Edible essence 8%
Emulsifying agent 5%
Foam cleaners 2%
Thickening agent 20%
Antibacterial 1%
Sweeting agent 2%
Described natural plant extracts is that pulverous Herba Pileae Scriptae extract and pulverous extract of magnolia mix in the ratio of 5:3, and wherein the sterling content of Herba Pileae Scriptae extract is 38%, and the sterling content of extract of magnolia is 38%.
Described film former is in carboxymethyl cellulose and chitosan, sodium alginate, modified starch, Pullulan, maltodextrin, guar gum, one or more in konjaku powder are mixed.
Described abrasivus is that the mixing of 1:5:4 ratio is obtained with weight ratio by silicon dioxide, calcium bicarbonate and calcium carbonate.
Described edible essence is bamboo essence and can menthol, is that the ratio mixing of 2:1 is obtained by bamboo essence and menthol with weight ratio.
The ratio mixing that described emulsifying agent is crosslinked carboxylic first first Starch Sodium, poloxamer, glyceryl stearate take weight ratio as 1:2:2 is obtained.
Described foam cleaners can select one or more mixing in lauryl triethanolamine sodium sulfate, sodium lauroyl sarcosine, sodium lauryl sulphate, laurylglutamic sodium obtained.
The form mixing of described thickening agent to be cyclodextrin and betacyclodextrin with weight ratio be 1:3 is obtained.
Described antibacterial is 2,4, and 4 '-trichlorine, 2 '-dihydroxy diphenyl ether, first nitre file, cetylpyridinium chloride are mixed.
Described sweeting agent is obtained with the mixing of the ratio of 3:1 by xylitol and sucralose.
Present invention also offers a kind of containing plant extract gargle tablet and preparation method thereof, made by following steps:
Step 1: film former is joined in deionized water, both weight ratios are 1:3, heat while stirring, and limit adds above-mentioned abrasivus, emulsifying agent, foam cleaners, thickening agent, mixing speed is set to 500r/min, when above mixture heat up 65 DEG C time add edible essence, antibacterial, sweeting agent, continue to keep this heating-up temperature, regulate mixing speed to be that 800r/min stirs 0.5h, then add natural plant extracts after being cooled to 45 DEG C, stir and form rubber cement after 0.5 hour;
Step 2: the rubber cement of gained in step 1 is made thin film, and ensure that it is by certain thickness;
Step 3: by the thin film evaporate to dryness film forming of gained in step 2, ensures that its moisture is 15%, after cooling section obtain described in containing plant extract gargle tablet.
Embodiment 2
Containing plant extract gargle tablet, as follows by the percentage by weight of each component of finished product dry weight:
Natural plant extracts 8%
Film former 30%
Abrasivus 13%
Edible essence 4%
Emulsifying agent 6%
Foam cleaners 10%
Thickening agent 25%
Antibacterial 3%
Sweeting agent 1%
Described natural plant extracts is that pulverous Herba Pileae Scriptae extract and pulverous extract of magnolia mix in the ratio of 8:4;
Preferably, in Herba Pileae Scriptae extract, sterling content is 25%, and in extract of magnolia, sterling content is 25%.
Described film former is in hydroxyethyl-cellulose and chitosan, sodium alginate, modified starch, Pullulan, maltodextrin, guar gum, one or more in konjaku powder are mixed.
Described abrasivus is that the mixing of 1:5:4 ratio is obtained with weight ratio by silicon dioxide, calcium bicarbonate and calcium carbonate.
Described edible essence is bamboo essence and can menthol, is that the ratio mixing of 2:1 is obtained by bamboo essence and menthol with weight ratio.
The ratio mixing that described emulsifying agent is crosslinked carboxylic first first Starch Sodium, poloxamer, glyceryl stearate take weight ratio as 1:2:2 is obtained.
Described foam cleaners can select one or more mixing in lauryl triethanolamine sodium sulfate, sodium lauroyl sarcosine, sodium lauryl sulphate, laurylglutamic sodium obtained.
The form mixing of described thickening agent to be cyclodextrin and betacyclodextrin with weight ratio be 1:3 is obtained.
Described foam cleaners selection lauryl triethanolamine sodium sulfate, sodium lauryl sulphate, laurylglutamic sodium are that the ratio mixing of 1:3:2 is obtained with weight ratio.
Described sweeting agent is obtained with the mixing of the ratio of 3:1 by xylitol and sucralose.
Present invention also offers a kind of containing plant extract gargle tablet and preparation method thereof, made by following steps:
Step 1: film former is joined in deionized water, both weight ratios are 1:3, heat while stirring, and limit adds above-mentioned abrasivus, emulsifying agent, foam cleaners, thickening agent, mixing speed is set to 500r/min, when above mixture heat up 65 DEG C time add edible essence, antibacterial, sweeting agent, continue to keep this heating-up temperature, regulate mixing speed to be that 800r/min stirs 0.5h, then add natural plant extracts after being cooled to 45 DEG C, stir and form rubber cement after 0.5 hour;
Step 2: the rubber cement of gained in step 1 is made thin film, and ensure that it is by certain thickness;
Step 3: by the thin film evaporate to dryness film forming of gained in step 2, ensures that its moisture is 15%, after cooling section obtain described in containing plant extract gargle tablet.
Embodiment 3
Containing plant extract gargle tablet, as follows by the percentage by weight of each component of finished product dry weight:
Natural plant extracts 15%
Film former 20%
Abrasivus 15%
Edible essence 14%
Emulsifying agent 10%
Foam cleaners 6%
Thickening agent 15%
Antibacterial 2%
Sweeting agent 3%
Described natural plant extracts is that pulverous Herba Pileae Scriptae extract and pulverous extract of magnolia mix in the ratio of 10:5;
Preferably, in Herba Pileae Scriptae extract, sterling content is 40%, and in extract of magnolia, sterling content is 40%.
Described film former use in hydroxypropyl cellulose and chitosan, sodium alginate, modified starch, Pullulan, maltodextrin, guar gum, konjaku powder one or more be mixed.
Described abrasivus is that the mixing of 1:5:4 ratio is obtained with weight ratio by silicon dioxide, calcium bicarbonate and calcium carbonate.
Described edible essence is bamboo essence and can menthol, is that the ratio mixing of 2:1 is obtained by bamboo essence and menthol with weight ratio.
The ratio mixing that described emulsifying agent is crosslinked carboxylic first first Starch Sodium, poloxamer, glyceryl stearate take weight ratio as 1:2:2 is obtained.
Described foam cleaners selection lauryl triethanolamine sodium sulfate, sodium lauryl sulphate, laurylglutamic sodium are that the ratio mixing of 1:3:2 is obtained with weight ratio.
The form mixing of described thickening agent to be cyclodextrin and betacyclodextrin with weight ratio be 1:3 is obtained.
Described antibacterial is chlorhexidine acetate, 2,4, and 4 '-trichlorine, 2 '-dihydroxy diphenyl ether, cetylpyridinium chloride are mixed.
Described sweeting agent is obtained with the mixing of the ratio of 3:1 by xylitol and sucralose.
Present invention also offers a kind of containing plant extract gargle tablet and preparation method thereof, made by following steps:
Step 1: film former is joined in deionized water, both weight ratios are 1:3, heat while stirring, and limit adds above-mentioned abrasivus, emulsifying agent, foam cleaners, thickening agent, mixing speed is set to 500r/min, when above mixture heat up 65 DEG C time add edible essence, antibacterial, sweeting agent, continue to keep this heating-up temperature, regulate mixing speed to be that 800r/min stirs 0.5h, then add natural plant extracts after being cooled to 45 DEG C, stir and form rubber cement after 0.5 hour;
Step 2: the rubber cement of gained in step 1 is made thin film, and ensure that it is by certain thickness;
Step 3: by the thin film evaporate to dryness film forming of gained in step 2, ensures that its moisture is 18%, after cooling section obtain described in containing plant extract gargle tablet.
Preferably, cooled thin film is cut into the section of 50mm × 40mm × 0.2mm.
Embodiment 4
Containing plant extract gargle tablet, as follows by the percentage by weight of each component of finished product dry weight:
Natural plant extracts 9%
Film former 20%
Abrasivus 25%
Edible essence 16%
Emulsifying agent 7%
Foam cleaners 5%
Thickening agent 15%
Antibacterial 1%
Sweeting agent 2%
Described natural plant extracts is that pulverous Herba Pileae Scriptae extract and pulverous extract of magnolia mix in the ratio of 10:5;
Preferably, in Herba Pileae Scriptae extract, sterling content is 50%, and in extract of magnolia, sterling content is 50%.
Described film former selects that carboxymethyl cellulose, hydroxyethyl-cellulose, hydroxypropyl cellulose take weight ratio as 1:2:3 and chitosan, one or more in sodium alginate, modified starch, Pullulan, maltodextrin, guar gum, konjaku powder are mixed.
Described abrasivus is that the mixing of 1:5:4 ratio is obtained with weight ratio by silicon dioxide, calcium bicarbonate and calcium carbonate.
Described edible essence is bamboo essence and can menthol, is that the ratio mixing of 2:1 is obtained by bamboo essence and menthol with weight ratio.
The ratio mixing that described emulsifying agent is crosslinked carboxylic first first Starch Sodium, poloxamer, glyceryl stearate take weight ratio as 1:2:2 is obtained.
Described foam cleaners selection lauryl triethanolamine sodium sulfate, sodium lauryl sulphate, laurylglutamic sodium are that the ratio mixing of 1:3:2 is obtained with weight ratio.
The form mixing of described thickening agent to be cyclodextrin and betacyclodextrin with weight ratio be 1:3 is obtained.
Described antibacterial is chlorhexidine acetate, 2,4, and 4 '-trichlorine, 2 '-dihydroxy diphenyl ether, cetylpyridinium chloride are by weight proportion for 1:1:14 is mixed.
Described sweeting agent is obtained with the mixing of the ratio of 3:1 by xylitol and sucralose.
Present invention also offers a kind of containing plant extract gargle tablet and preparation method thereof, made by following steps:
Step 1: film former is joined in deionized water, both weight ratios are 1:3, heat while stirring, and limit adds above-mentioned abrasivus, emulsifying agent, foam cleaners, thickening agent, mixing speed is set to 500r/min, when above mixture heat up 65 DEG C time add edible essence, antibacterial, sweeting agent, continue to keep this heating-up temperature, regulate mixing speed to be that 800r/min stirs 0.5h, then add natural plant extracts after being cooled to 45 DEG C, stir and form rubber cement after 0.5 hour;
Step 2: the rubber cement of gained in step 1 is made thin film, and ensure that it is by certain thickness;
Step 3: by the thin film evaporate to dryness film forming of gained in step 2, ensures that its moisture is 18%, after cooling section obtain described in containing plant extract gargle tablet.
Preferably, cooled thin film is cut into the section of 50mm × 40mm × 0.2mm.
Embodiment 5
Containing plant extract gargle tablet, as follows by the percentage by weight of each component of finished product dry weight:
Natural plant extracts 9%
Film former 20%
Abrasivus 25%
Edible essence 16%
Emulsifying agent 7%
Foam cleaners 5%
Thickening agent 15%
Antibacterial 1%
Sweeting agent 2%
Described natural plant extracts is that pulverous Herba Pileae Scriptae extract and pulverous extract of magnolia mix in the ratio of 10:5;
Preferably, in Herba Pileae Scriptae extract, sterling content is 50%, and in extract of magnolia, sterling content is 50%.
The ratio mixing of described film former is carboxymethyl cellulose, hydroxyethyl-cellulose, hydroxypropyl cellulose to take weight ratio as 1:2:3 and chitosan, Pullulan, maltodextrin with weight ratio be 1:1:1 is obtained.
Described abrasivus is that the mixing of 1:5:4 ratio is obtained with weight ratio by silicon dioxide, calcium bicarbonate and calcium carbonate.
Described edible essence is bamboo essence and can menthol, is that the ratio mixing of 2:1 is obtained by bamboo essence and menthol with weight ratio.
The ratio mixing that described emulsifying agent is crosslinked carboxylic first first Starch Sodium, poloxamer, glyceryl stearate take weight ratio as 1:2:2 is obtained.
Described foam cleaners selection lauryl triethanolamine sodium sulfate, sodium lauryl sulphate, laurylglutamic sodium are that the ratio mixing of 1:3:2 is obtained with weight ratio.
The form mixing of described thickening agent to be cyclodextrin and betacyclodextrin with weight ratio be 1:3 is obtained.
Described antibacterial is chlorhexidine acetate, 2,4, and 4 '-trichlorine, 2 '-dihydroxy diphenyl ether, cetylpyridinium chloride are by weight proportion for 1:1:1 is mixed.
Described sweeting agent is obtained with the mixing of the ratio of 3:1 by xylitol and sucralose.
Present invention also offers a kind of containing plant extract gargle tablet and preparation method thereof, made by following steps:
Step 1: film former is joined in deionized water, both weight ratios are 1:3, heat while stirring, and limit adds above-mentioned abrasivus, emulsifying agent, foam cleaners, thickening agent, mixing speed is set to 500r/min, when above mixture heat up 65 DEG C time add edible essence, antibacterial, sweeting agent, continue to keep this heating-up temperature, regulate mixing speed to be that 800r/min stirs 0.5h, then add natural plant extracts after being cooled to 45 DEG C, stir and form rubber cement after 0.5 hour;
Step 2: the rubber cement of gained in step 1 is made thin film, and ensure that it is by certain thickness;
Step 3: by the thin film evaporate to dryness film forming of gained in step 2, ensures that its moisture is 18%, after cooling section obtain described in containing plant extract gargle tablet.
Preferably, cooled thin film is cut into the section of 50mm × 40mm × 0.2mm.
Claims (9)
1., containing a plant extract gargle tablet, it is characterized in that: as follows by the percentage by weight of each component of finished product dry weight:
Natural plant extracts 8-15%
Film former 20-40%
Abrasivus 10-25%
Edible essence 4-16%
Emulsifying agent 5-10%
Foam cleaners 2-10%
Thickening agent 15-25%
Antibacterial 1 ~ 3%
Sweeting agent 1 ~ 3%
Described natural plant extracts is that pulverous Herba Pileae Scriptae extract and pulverous extract of magnolia mix in the ratio of 5 ~ 10:3 ~ 5;
Described film former can be one or more and chitosan in carboxymethyl cellulose, hydroxyethyl-cellulose, hydroxypropyl cellulose, one or more in sodium alginate, modified starch, Pullulan, maltodextrin, guar gum, konjaku powder are mixed;
Described abrasivus is that the mixing of 1:5:4 ratio is obtained with weight ratio by silicon dioxide, calcium bicarbonate and calcium carbonate;
Described edible essence is bamboo essence and can menthol, is that the ratio mixing of 2:1 is obtained by bamboo essence and menthol with weight ratio;
The ratio mixing that described emulsifying agent is crosslinked carboxylic first first Starch Sodium, poloxamer, glyceryl stearate take weight ratio as 1:2:2 is obtained;
Described foam cleaners can select one or more mixing in lauryl triethanolamine sodium sulfate, sodium lauroyl sarcosine, sodium lauryl sulphate, laurylglutamic sodium obtained;
The form mixing of described thickening agent to be cyclodextrin and betacyclodextrin with weight ratio be 1:3 is obtained;
described antibacterial is chlorhexidine acetate, benzalkonium bromide, 2,4, and one or more in 4 '-trichlorine, 2 '-dihydroxy diphenyl ether, first nitre file, cetylpyridinium chloride are mixed;
Described sweeting agent is obtained with the mixing of the ratio of 3:1 by xylitol and sucralose.
2. as claimed in claim 1 a kind of containing plant extract gargle tablet, it is characterized in that: in described Herba Pileae Scriptae extract, sterling content is 25 ~ 50%.
3. as claimed in claim 1 a kind of containing plant extract gargle tablet, it is characterized in that: in described extract of magnolia, sterling content is 25 ~ 50%.
4. as claimed in claim 1 a kind of containing plant extract gargle tablet, it is characterized in that: described film former selects that carboxymethyl cellulose, hydroxyethyl-cellulose, hydroxypropyl cellulose take weight ratio as 1:2:3 and chitosan, one or more in sodium alginate, modified starch, Pullulan, maltodextrin, guar gum, konjaku powder are mixed.
5. as claimed in claim 4 a kind of containing plant extract gargle tablet, it is characterized in that: described film former selects carboxymethyl cellulose, hydroxyethyl-cellulose, hydroxypropyl cellulose to take weight ratio as 1:2:3 and chitosan, Pullulan, maltodextrin with weight ratio to be the ratio mixing of 1:1:1 obtained.
6. as claimed in claim 1 a kind of containing plant extract gargle tablet, it is characterized in that: described foam cleaners selection lauryl triethanolamine sodium sulfate, sodium lauryl sulphate, laurylglutamic sodium are that the ratio mixing of 1:3:2 is obtained with weight ratio.
7. as claimed in claim 1 a kind of containing plant extract gargle tablet, it is characterized in that: the chlorhexidine acetate selected, 2,4 of described antibacterial, 4 '-trichlorine, 2 '-dihydroxy diphenyl ether and cetylpyridinium chloride mix with the ratio of 1:1:1.
8. a kind of manufacture method containing plant extract gargle tablet as claimed in claim 1, is characterized in that following steps:
Step 1: film former is joined in deionized water, both weight ratios are 1:3, heat while stirring, and limit adds above-mentioned abrasivus, emulsifying agent, foam cleaners, thickening agent, mixing speed is set to 500r/min, when above mixture heat up 65 DEG C time add edible essence, antibacterial, sweeting agent, continue to keep this heating-up temperature, regulate mixing speed to be that 800r/min stirs 0.5h, then add natural plant extracts after being cooled to 45 DEG C, stir and form rubber cement after 0.5 hour;
Step 2: the rubber cement of gained in step 1 is made thin film, and ensure that it is by certain thickness;
Step 3: by the thin film evaporate to dryness film forming of gained in step 2, ensures that its moisture is 15% ~ 18%, after cooling section obtain described in containing plant extract gargle tablet.
9. a kind of manufacture method containing plant extract gargle tablet as claimed in claim 1, is characterized in that: the section cooled thin film being cut into 50mm × 40mm × 0.2mm.
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| CN201410716890.6A CN104473822A (en) | 2014-12-02 | 2014-12-02 | Mouthwash tablet containing plant extract and preparation method of mouthwash tablet |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105410913A (en) * | 2015-12-01 | 2016-03-23 | 辽宁三合酒业有限公司 | Preparation method of chitosan oligosaccharide mouth cleaning buccal tablets |
| CN106344428A (en) * | 2016-07-27 | 2017-01-25 | 青岛琛蓝海洋生物工程有限公司 | Marine polysaccharide-based dry mouth symptom relieving mouthwash and preparation method thereof |
| US11319566B2 (en) | 2017-04-14 | 2022-05-03 | Capsugel Belgium Nv | Process for making pullulan |
| CN115282076A (en) * | 2022-07-28 | 2022-11-04 | 广州洁生日化有限公司 | Oral care cleaning tablet and preparation method and use method thereof |
| US11576870B2 (en) | 2017-04-14 | 2023-02-14 | Capsugel Belgium Nv | Pullulan capsules |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105410913A (en) * | 2015-12-01 | 2016-03-23 | 辽宁三合酒业有限公司 | Preparation method of chitosan oligosaccharide mouth cleaning buccal tablets |
| CN106344428A (en) * | 2016-07-27 | 2017-01-25 | 青岛琛蓝海洋生物工程有限公司 | Marine polysaccharide-based dry mouth symptom relieving mouthwash and preparation method thereof |
| US11319566B2 (en) | 2017-04-14 | 2022-05-03 | Capsugel Belgium Nv | Process for making pullulan |
| US11576870B2 (en) | 2017-04-14 | 2023-02-14 | Capsugel Belgium Nv | Pullulan capsules |
| US11878079B2 (en) | 2017-04-14 | 2024-01-23 | Capsugel Belgium Nv | Pullulan capsules |
| CN115282076A (en) * | 2022-07-28 | 2022-11-04 | 广州洁生日化有限公司 | Oral care cleaning tablet and preparation method and use method thereof |
| CN115282076B (en) * | 2022-07-28 | 2023-06-27 | 广州洁生日化有限公司 | Oral care cleaning sheet and preparation method and application method thereof |
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