CN107243043A - A kind of Chinese medicine treated diabetes and control its complication to occur - Google Patents

A kind of Chinese medicine treated diabetes and control its complication to occur Download PDF

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Publication number
CN107243043A
CN107243043A CN201710704155.7A CN201710704155A CN107243043A CN 107243043 A CN107243043 A CN 107243043A CN 201710704155 A CN201710704155 A CN 201710704155A CN 107243043 A CN107243043 A CN 107243043A
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chinese medicine
medicine
complication
diabetes
control
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刘明州
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention discloses a kind of Chinese medicine treated diabetes and control its complication to occur, it is related to a kind of Chinese medicine, and in particular to a kind of Chinese medicine for treating diabetes.Include the raw material of following ratio of weight and number:American Ginseng 33 37;The Radix Astragali 142 158;Chinese yam 95 105;Dark plum 76 84;Gorgon fruit 67 73;Sea-buckthorn 100 110;The fruit of Chinese magnoliavine 52 58;Spina date seed 33 37;Pumpkin powder 95 105;The root of kudzu vine 71 79;Radix glycyrrhizae 33 37;Chromium gluconate 0.12 0.124.The composition that the present invention solves existing treatment Chinese medicine for treating diabetes is more, is not suitable for being used for a long time.The problem of above-mentioned patent controls the DeGrain of diabetic complication in addition.

Description

A kind of Chinese medicine treated diabetes and control its complication to occur
Technical field
The present invention relates to a kind of Chinese medicine, and in particular to a kind of Chinese medicine for treating diabetes.
Background technology
Diabetes are one group of metabolic diseases being characterized with hyperglycaemia.Hyperglycaemia be due to then defect of insulin secretion or Its biological agent is damaged, or both have concurrently and cause.Long-standing hyperglycaemia during diabetes, cause various tissues, particularly eye, Kidney, heart, blood vessel, the chronic lesion of nerve, dysfunction.The cause of disease of diabetes is complicated, and final conclusion is there is no so far, is led to Often think with inherent cause and environmental factor and interaction complicated therebetween is relevant.Diabetes classification is insulin Dependent diabetes (I type) and Non-Insulin Dependent Diabetes Mellitus (II type).
The chronic complicating diseases treatment of diabetes is also major issue, because traditional treating diabetes lay stress on blood On sugar, the change of blood pressure, therefore diabetic complication never has and is controlled effectively.The pathology of the complication of diabetes is former Cause, actual is all the blood vessel scleratheroma lesion of correspondence organ, and simply kidney, eye, pedopathy are brain, heart based on tiny blood vessels Disease is that based on medium vessels, but its pathologic basis is all atherosclerosis.And cause the immediate cause of artery sclerosis not lie in The height of blood glucose, and the number of blood fat, especially HDL HDL be(Hereinafter referred to as HDL)Number and oxidation Low-density lipoprotein Ox-LDL(Hereinafter referred to as Ox-LDL)Situation.Long-term blood glucose increases, and big blood vessel, capilary are damaged and jeopardized The heart, brain, kidney, peripheral nerve, eyes, foot etc..
Chinese patent literature CN103495020B discloses a kind of Chinese medicine for treating diabetes, and it is by following weight proportion Material medicine component composition:Dried rhizome of rehmannia 15-20g, radix scrophulariae 20-30g, wind-weed 10-15g, root of kudzu vine 20-30g, pollen 10-15g, Asparagus fern 15-20g, tuber of dwarf lilyturf 15-20g, Radix Astragali 20-30g, Chinese yam 10-15g, coptis 6-9g, ginseng 6-9g, rhizoma atractylodis 10-15g, radix glycyrrhizae 6-9g.The invention Chinese medicine has the advantages that good effect, cure rate are high, had no toxic side effect.
Chinese patent literature CN102274471B discloses a kind of pharmaceutical composition for treating diabetes.The invention includes: 16 parts of lucid asparagus;30 parts of radix scutellariae;16 parts of radix scrophulariae;30 parts of the Radix Astragali;16 parts of American Ginseng;30 parts of root of Chinese trichosanthes;16 parts of the fruit of Chinese magnoliavine; 12 parts of Radix Angelicae Sinensis;30 parts of Semen Cuscutae;See that blood is blue or green 10 parts;45 parts of sealwort;16 parts of cloves;30 parts of Chinese yam;16 parts of the root bark of tree peony;In vain 16 parts of art;30 parts of the dried rhizome of rehmannia;20 parts of radix pseudostellariae;30 parts of the tuber of dwarf lilyturf;20 parts of the wind-weed;16 parts of Poria cocos;16 parts of the fruit of Chinese wolfberry;Dogwood fruit 30 parts;35 parts of Ramulus euonymi;30 parts of gypsum;20 parts of rhizoma alismatis;15 parts of mast;30 parts of Radix Codonopsis;20 parts of turmeric;Caulis lonicerae 30 parts;30 parts of pipewort;30 parts of the coptis;9 parts of honey-fried licorice root;12 parts of rheum officinale;30 parts of radix polygonati officinalis;30 parts of the root of kudzu vine;Ligusticum wallichii 16 Part;Wherein, radix scutellariae, radix scrophulariae, the root bark of tree peony, the dried rhizome of rehmannia, the wind-weed, Radix Codonopsis and the coptis are externally applied drug, and remaining is medicine for oral administration.The drug regimen Thing can effectively treat I-IV patients with type Ⅰ DM and its complication and hypertension, high fat of blood, hyperglycaemia.
Above-mentioned two patent Chinese medicinal ingredients are more, are not suitable for being used for a long time.Above-mentioned patent controls diabetic complication in addition DeGrain.
The content of the invention
The present invention provides a kind of Chinese medicine treated diabetes and control its complication to occur, and the present invention solves existing treatment The composition of Chinese medicine for treating diabetes is more, is not suitable for being used for a long time;And the DeGrain of above-mentioned patent control diabetic complication Problem.
To solve the above problems, the present invention is adopted the following technical scheme that:One kind treats diabetes and controls its complication hair Raw Chinese medicine, includes the raw material of following ratio of weight and number:American Ginseng 33-37;Radix Astragali 142-158;Chinese yam 95-105;Dark plum 76- 84;Gorgon fruit 67-73;Sea-buckthorn 100-110;Fruit of Chinese magnoliavine 52-58;Spina date seed 33-37;Pumpkin powder 95-105;Root of kudzu vine 71-79;Radix glycyrrhizae 33-37;Chromium gluconate 0.12-0.124.
Its preparation process is:(One)By said medicine broken wall;(Two)Heat filling is carried out to medicine and extracts concentration;(Three)Will be dense Medicine, which is dried, after contracting dusts.
Its preparation process(One), medicine broken wall uses wall-breaking machine rotating speed for 40000-45000 revs/min;Wall-breaking machine is each The medicine of 0.4-1 kilograms of processing, broken time is 0.1-2 minutes.
Its preparation process(Two)Medicine carries out heat filling extraction concentration process:
(1)Medicinal material is put into extractor, the water of 5-10 times of Chinese medicine weight is added;
(2)After extract solution is heated into boiling 20--30 minutes, concentration tank is pumped into by 1/3rd extract solution;Make inspissated juice Temperature is maintained at 80 DEG C or so, and vacuum is maintained at -0.05 and arrives -0.08MPA, is concentrated to paste.
Its preparation process(Three)Dry to dust and use vacuum rake dryer, pharmaceutical drying heating-up temperature is 80-99 DEG C.
The Chinese medicine preparation of the present invention is using the Radix Astragali, Chinese yam as monarch:Wherein the Radix Astragali is sweet, slightly warm in nature, can tonifying middle-Jiao and Qi.Chinese yam taste It is sweet mild-natured, can kidney tonifying Yiyang, and can strengthening spleen, tonifying kidney;Using American Ginseng as ministerial drug, monarch drug in a prescription can be strengthened and reinforce the kidney taste by being shared with pumpkin powder The moon, the work(invigorated the spleen and benefited qi;Sea-buckthorn can improve lipids contents and ratio, alleviate sugar metabolism levels;Spina date seed convergence gas is cloudy;The fruit of Chinese magnoliavine Mitigate beta Cell of islet damage, increase its number;Dark plum energy insulin secretion accelerating, it is hypoglycemic, stimulate circulation, improve glycosuria Sick pruritis;Gorgon fruit and radix glycyrrhizae can promote to absorb.It is altogether adjuvant collectively for diabetes patient's glucose -lipid metabolism disorder mechanism. Above all medicines share, plays mediation the five internal organs altogether, and kidney tonifying enriching yin, strengthening the spleen and replenishing qi, the work(promoted the production of body fluid to quench thirst cures mainly spleen kidney deficiency, gas the moon two Empty quenches one's thirst.
Present invention treatment diabetes and the Chinese medicine for controlling its complication to occur are broken by Chinese medicine using modern biotechnology Wall, circumfluence distillation concentration, finally drying are dusted, so that the active component in pharmaceutical formulation is retained very well, improved Therapeutic effect.Present invention treatment diabetes and the Chinese medicine for controlling its complication to occur can be free from side effects with long-term taking, be treated Diabetes and complication work well, and cure rate is high.
Embodiment
The present invention is described in detail with optimal embodiment below.
A kind of Chinese medicine treated diabetes and control its complication to occur, includes the raw material of following ratio of weight and number:The West Join 33-37;Radix Astragali 142-158;Chinese yam 95-105;Dark plum 76-84;Gorgon fruit 67-73;Sea-buckthorn 100-110;Fruit of Chinese magnoliavine 52-58;Acid Jujube kernel 33-37;Pumpkin powder 95-105;Root of kudzu vine 71-79;Radix glycyrrhizae 33-37;Chromium gluconate 0.12-0.124.
Its preparation process is:(One)By said medicine broken wall;(Two)Heat filling is carried out to medicine and extracts concentration;(Three)Will be dense Medicine, which is dried, after contracting dusts.
Its preparation process(One), medicine broken wall uses wall-breaking machine rotating speed for 40000-45000 revs/min;Wall-breaking machine is each The medicine of 0.4-1 kilograms of processing, broken time is 0.5-5 minutes.
Its preparation process(Two)Medicine carries out heat filling extraction concentration process:
(1)Medicinal material is put into extractor, the water of 5-10 times of Chinese medicine weight is added;
(2)After extract solution is heated into boiling 20--30 minutes, concentration tank is pumped into by 1/3rd extract solution;Make inspissated juice Temperature is maintained at 80 DEG C or so, and vacuum is maintained at -0.05 and arrives -0.08MPA, and the indirect steam produced during concentration passes through condenser With cooler become condensate liquid be back to extractor do novel solvent add medicine in, novel solvent from top to bottom pass through medicinal material layer to extraction Soluble component in pot bottom, medicinal material is dissolved in extractor internal solvent, and extract solution is pumped into concentration tank through suction filtering tube, and concentration is produced Indirect steam deliver to extractor again and do novel solvent, novel solvent refluxing extraction is formed, until complete dissolution (extracting liquid colourless) is dense Contracting proceeds, until being condensed into the proportion ointment of needs;Colourless liquid in extractor can be multiplexed next time, if organic solvent Extract, then first add suitable quantity of water, open straight system and chuck hot water, recycling design.
Its preparation process(Three)Dry to dust and use vacuum rake dryer, medicine is added from middle above housing, Under the stirring of the rake teeth constantly rotated, when material is contacted with housing wall, surface is constantly updated, and is dried medicine heating-up temperature and is 80-99 DEG C, medicine is by steam(Or hot water, conduction oil)Indirectly heat, and the moisture of Chinese medicine is vaporized, the moisture of vaporization is by true Empty pump is taken away in time.
Dried material is by the indirectly heat of heat carrier, and breaking-wall cell is a kind of superfine powder process technology.If Chinese medicine Crushed using usual manner, its single particle is often made up of several or dozens of cell, and the sporoderm-broken rate of cell is extremely low.Chinese medicine Breaking-wall cell ultramicro grinding process technology can fully discharge medicinal material active ingredient.After breaking-wall cell, intracellular water Part oil content is moved out, and particulate surface is showed semi-moist state, stable particle cluster can be formed between particle and particle, each Particle cluster all includes the traditional Chinese medicine ingredients of same ratio.The physical arrangement of the particle cluster is with each composition HLB value in component(It is hydrophilic, parent Oily equilibrium valve), ductility, brokenness, various combination and the different interactions such as proportion and it is different.This structure is conducive to people Absorption and utilization of the body to Chinese medicine.The fat-soluble enhancing of Chinese medicine, readily passes through adipose membrane, and the blood concentration in human body can be put forward rapidly, Reach the purpose for curing disease.
The present invention Chinese medicine instructions of taking be:Every pair of 30-40 grams of dose, divides 3 times and is taken with warm water by daily 1 pair, the early, noon Before meals, late one after each meal.It is within 1 month a small course for the treatment of, is within 3 months a big course for the treatment of.
Share 30 people and take this medicine, wherein 15 people are IDDM, complication is:Dry, four limbs are aching and limp, heart and brain blood Pipe disease, gastrointestinal disease;15 people are type II diabetes, and complication is:Kidney trouble, DPN, illness in eye etc..
The people of first stage 30 takes the small course for the treatment of of medicine one of the present invention respectively:30 people's drys, the constitutional symptom such as four limbs are aching and limp is bright Aobvious to improve, blood glucose, glucose in urine start to fall after rise;The four limbs of type i diabetes people are aching and limp, and cardiovascular and cerebrovascular disease, gastrointestinal disease all take a turn for the better; Type II diabetes, complication is:Kidney trouble, DPN, Ocular indications have 14 people improvement, and 1 people does not have effect.This stage takes Obvious effective rate is 96.7% after medicine.
Above-mentioned 30 people of second stage continues to take the big course for the treatment of of medicine one of the present invention:30 people's blood glucose, glucose in urine are decreased obviously, many Urine, hunger and insomnia are clearly better, and the people of syndrome 30 all mitigates;
Phase III above-mentioned 30 people continues to take the big course for the treatment of of medicine one of the present invention:Blood glucose, glucose in urine tend to be normal, mild complications It is clearly better, tuberculosis, Peripheral neuropathy and skin infection, urinary tract infections are improved in varying degrees;
Above-mentioned 30 people of fourth stage continues to take the big course for the treatment of of medicine one of the present invention:Blood glucose, glucose in urine keep normal condition, and severe is simultaneously Send out disease such as cardiovascular disease, nephrosis, PVR etc. and good favourable turn occur.Last entirety obtains control close to normally.
By the contrast in aforementioned four stage, Chinese medicine of the present invention is mainly for blood glucose is unstable, diabetes complication(The heart Cranial vascular disease, kidney trouble, gastrointestinal disease, DPN, illness in eye etc.), take this formula one month, above symptom can be obtained To preferable improvement, adhere to taking, blood glucose can obtain stabilization, and no longer fluctuated, complication can disappear.Effective percentage reaches 96.7%.This product patient of 3 years is taken, the generation without any diabetic complication is not only high without the patient taken Blood glucose is fluctuated, and has complication more.
Finally it should be noted that:Obviously, above-described embodiment is only intended to clearly illustrate example of the present invention, and simultaneously The non-restriction to embodiment.For those of ordinary skill in the field, it can also do on the basis of the above description Go out other various forms of changes or variation.There is no necessity and possibility to exhaust all the enbodiments.And thus drawn Among the obvious changes or variations that Shen goes out is still in protection scope of the present invention.

Claims (5)

1. a kind of Chinese medicine treated diabetes and control its complication to occur, it is characterised in that including following ratio of weight and number Raw material:American Ginseng 33-37;Radix Astragali 142-158;Chinese yam 95-105;Dark plum 76-84;Gorgon fruit 67-73;Sea-buckthorn 100-110;The five tastes Sub- 52-58;Spina date seed 33-37;Pumpkin powder 95-105;Root of kudzu vine 71-79;Radix glycyrrhizae 33-37;Chromium gluconate 0.12-0.124.
2. a kind of as claimed in claim 1 treat diabetes and the Chinese medicine of control its complication generation, it is characterised in that it is prepared Step is:(One)By said medicine broken wall;(Two)Heat filling is carried out to medicine and extracts concentration;(Three)Medicine is done after concentrating It is dry to dust.
3. a kind of as claimed in claim 2 treat diabetes and the Chinese medicine of control its complication generation, it is characterised in that it is prepared Step(One), medicine broken wall uses wall-breaking machine rotating speed for 40000-45000 revs/min;Wall-breaking machine processes 0.4-1 kilograms every time Medicine, broken time is 0.1-2 minutes.
4. a kind of as claimed in claim 2 treat diabetes and the Chinese medicine of control its complication generation, it is characterised in that it is prepared Step(Two)Medicine carries out heat filling extraction concentration process:
(1)Medicinal material is put into extractor, the water of 5-10 times of Chinese medicine weight is added;
(2)After extract solution is heated into boiling 20--30 minutes, concentration tank is pumped into by 1/3rd extract solution;Make inspissated juice Temperature is maintained at 80 DEG C or so, and vacuum is maintained at -0.05 and arrives -0.08MPA, is concentrated to paste.
5. a kind of as claimed in claim 2 treat diabetes and the Chinese medicine of control its complication generation, it is characterised in that it is prepared Step(Three)Dry to dust and use vacuum rake dryer, pharmaceutical drying heating-up temperature is 80-99 DEG C.
CN201710704155.7A 2017-08-17 2017-08-17 A kind of Chinese medicine treated diabetes and control its complication to occur Pending CN107243043A (en)

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CN110613771A (en) * 2019-11-05 2019-12-27 任国旺 Manufacturing process of eye patch for relieving dry eyes, unsmooth eyes and asthenopia
CN113384644A (en) * 2021-07-29 2021-09-14 吴洪宇 A Chinese medicinal composition and its preparation method

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