CN108392583A - A kind of Chinese medicine preparation for treating diabetic nephropathy - Google Patents

A kind of Chinese medicine preparation for treating diabetic nephropathy Download PDF

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Publication number
CN108392583A
CN108392583A CN201810411479.6A CN201810411479A CN108392583A CN 108392583 A CN108392583 A CN 108392583A CN 201810411479 A CN201810411479 A CN 201810411479A CN 108392583 A CN108392583 A CN 108392583A
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radix
chinese medicine
chinese
diabetic nephropathy
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南一
袁玲
毛熊杰
牛阳
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Ningxia Medical University
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Ningxia Medical University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/066Clavicipitaceae
    • A61K36/068Cordyceps
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/746Morinda
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888Pinellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964Anemarrhena
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
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Abstract

The invention discloses a kind of Chinese medicine preparations for treating diabetic nephropathy, are made of corn stigma, Morinda officinalis, rhizoma imperatae, monkshood, pueraria lobata, Chinese cassia tree, silkworm chrysalis, Radix Ophiopogonis, radix scrophulariae, root of Chinese trichosanthes, Radix Angelicae Sinensis, Radix Rehmanniae, the tuber of pinellia, rhizoma anemarrhenae, Poria cocos, radix achyranthis bidentatae, radix cyathulae, Cordceps militaris, peach kernel, Agricus blazei.Compared with prior art, the present invention uses natural traditional Chinese medicine for raw material, without side-effects, no dependence, utilize the comprehensive function of each drug component, blood glucose, good treatment diabetes can be reduced, while also there is certain therapeutic effect to nephrosis, and can improve the immunity of the human body, it has the value of popularization and application.

Description

A kind of Chinese medicine preparation for treating diabetic nephropathy
Technical field
The present invention relates to a kind of Chinese medicine more particularly to a kind of Chinese medicine preparations for treating diabetic nephropathy.
Background technology
Diabetes are one group of metabolic diseases characterized by hyperglycemia.Hyperglycemia be then due to defect of insulin secretion or Its biological effect is impaired, or both have concurrently and cause.Long-standing hyperglycemia when diabetes, cause various tissues, especially eye, Kidney, heart, blood vessel, the chronic lesion of nerve, dysfunction.In the prior art, diabetes are always the doctor that medicine is difficult to capture Problem is learned, and in line with the spirit for improving therapeutic effect, it needs constantly to improve and innovation.
Invention content
The purpose of the present invention is that solve the above-mentioned problems and provides a kind of Chinese medicine preparation for treating diabetic nephropathy.
The present invention is achieved through the following technical solutions above-mentioned purpose:
The present invention is by corn stigma, Morinda officinalis, rhizoma imperatae, monkshood, pueraria lobata, Chinese cassia tree, silkworm chrysalis, Radix Ophiopogonis, radix scrophulariae, root of Chinese trichosanthes, Radix Angelicae Sinensis, life Ground, the tuber of pinellia, rhizoma anemarrhenae, Poria cocos, radix achyranthis bidentatae, radix cyathulae, Cordceps militaris, peach kernel, Agricus blazei composition.
Preferably, by weight, the corn stigma accounts for 2-5%, the Morinda officinalis accounts for 2-5%, the rhizoma imperatae accounts for 4-8%, institute State that monkshood accounts for 3-6%, the pueraria lobata accounts for 1-2%, the Chinese cassia tree accounts for 1-3%, the silkworm chrysalis accounts for 1-3%, the Radix Ophiopogonis accounts for 1-2%, described Radix scrophulariae accounts for 2-4%, the root of Chinese trichosanthes accounts for 3-5%, the Radix Angelicae Sinensis accounts for 3-5%, the Radix Rehmanniae accounts for 1-2%, the tuber of pinellia accounts for 3-5%, described Rhizoma anemarrhenae accounts for 1-2%, the Poria cocos accounts for 1-3%, the radix achyranthis bidentatae accounts for 5-8%, the radix cyathulae accounts for 5-8%, the Cordceps militaris accounts for 20- 25%, the peach kernel accounts for 8-10%, the Agricus blazei accounts for 8-15%.
Preferably, by weight, per 100g containing the corn stigma 3g, the Morinda officinalis 3g, the rhizoma imperatae 5g, described attached Sub- 5g, the pueraria lobata 1.5g, the Chinese cassia tree 2.5g, the silkworm chrysalis 3g, the Radix Ophiopogonis 1.5g, the radix scrophulariae 3.5g, the smallpox Powder 5g, the Radix Angelicae Sinensis 4g, the Radix Rehmanniae 1.5g, the tuber of pinellia 3.5g, the rhizoma anemarrhenae 1.5g, the Poria cocos 2.5g, the bosom ox Knee 8g, the radix cyathulae 8g, the Cordceps militaris 20g, the peach kernel 8g, the Agricus blazei 10g.
Further, after all medicament mixing of each component, 3 times of medicine gross weight is added water to, 50min are impregnated, in 90-100 DEG C heating 10min, then reduces temperature to 50-60 DEG C, keeps the temperature 10min, then increase temperature to 90-100 DEG C, continue to heat 5min is cooled to 50-60 DEG C again, keeps the temperature 5min, cooling, and filtering removes slag, oral solution is made after packaging and forms, moreover it is possible to Enough that the oral solution heating evaporation is condensed into paste medicinal extract, dries pulverizing, tablet or pill is made in pelletizing press sheet.It can also Granule is made in the medicinal extract dries pulverizing.
The beneficial effects of the present invention are:
The present invention is a kind of Chinese medicine preparation for treating diabetic nephropathy, compared with prior art, the present invention use natural traditional Chinese medicine for Raw material, without side-effects, no dependence can reduce blood glucose, good treatment glycosuria using the comprehensive function of each drug component Disease, while also there is certain therapeutic effect to nephrosis, and can improve the immunity of the human body, it has the value of popularization and application.
Specific implementation mode
The invention will be further described below:
The present invention is by corn stigma, Morinda officinalis, rhizoma imperatae, monkshood, pueraria lobata, Chinese cassia tree, silkworm chrysalis, Radix Ophiopogonis, radix scrophulariae, root of Chinese trichosanthes, Radix Angelicae Sinensis, life Ground, the tuber of pinellia, rhizoma anemarrhenae, Poria cocos, radix achyranthis bidentatae, radix cyathulae, Cordceps militaris, peach kernel, Agricus blazei composition.
Preferably, by weight, the corn stigma accounts for 2-5%, the Morinda officinalis accounts for 2-5%, the rhizoma imperatae accounts for 4-8%, institute State that monkshood accounts for 3-6%, the pueraria lobata accounts for 1-2%, the Chinese cassia tree accounts for 1-3%, the silkworm chrysalis accounts for 1-3%, the Radix Ophiopogonis accounts for 1-2%, described Radix scrophulariae accounts for 2-4%, the root of Chinese trichosanthes accounts for 3-5%, the Radix Angelicae Sinensis accounts for 3-5%, the Radix Rehmanniae accounts for 1-2%, the tuber of pinellia accounts for 3-5%, described Rhizoma anemarrhenae accounts for 1-2%, the Poria cocos accounts for 1-3%, the radix achyranthis bidentatae accounts for 5-8%, the radix cyathulae accounts for 5-8%, the Cordceps militaris accounts for 20- 25%, the peach kernel accounts for 8-10%, the Agricus blazei accounts for 8-15%.
Preferably, by weight, per 100g containing the corn stigma 3g, the Morinda officinalis 3g, the rhizoma imperatae 5g, described attached Sub- 5g, the pueraria lobata 1.5g, the Chinese cassia tree 2.5g, the silkworm chrysalis 3g, the Radix Ophiopogonis 1.5g, the radix scrophulariae 3.5g, the smallpox Powder 5g, the Radix Angelicae Sinensis 4g, the Radix Rehmanniae 1.5g, the tuber of pinellia 3.5g, the rhizoma anemarrhenae 1.5g, the Poria cocos 2.5g, the bosom ox Knee 8g, the radix cyathulae 8g, the Cordceps militaris 20g, the peach kernel 8g, the Agricus blazei 10g.
Further, after all medicament mixing of each component, 3 times of medicine gross weight is added water to, 50min are impregnated, in 90-100 DEG C heating 10min, then reduces temperature to 50-60 DEG C, keeps the temperature 10min, then increase temperature to 90-100 DEG C, continue to heat 5min is cooled to 50-60 DEG C again, keeps the temperature 5min, cooling, and filtering removes slag, oral solution is made after packaging and forms, moreover it is possible to Enough that the oral solution heating evaporation is condensed into paste medicinal extract, dries pulverizing, tablet or pill is made in pelletizing press sheet.It can also Granule is made in the medicinal extract dries pulverizing.
The basic principles and main features and advantages of the present invention of the present invention have been shown and described above.The technology of the industry Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this The principle of invention, without departing from the spirit and scope of the present invention, various changes and improvements may be made to the invention, these changes Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its Equivalent thereof.

Claims (6)

1. a kind of Chinese medicine preparation for treating diabetic nephropathy, it is characterised in that:By corn stigma, Morinda officinalis, rhizoma imperatae, monkshood, Pueraria lobota Root, Chinese cassia tree, silkworm chrysalis, Radix Ophiopogonis, radix scrophulariae, root of Chinese trichosanthes, Radix Angelicae Sinensis, Radix Rehmanniae, the tuber of pinellia, rhizoma anemarrhenae, Poria cocos, radix achyranthis bidentatae, radix cyathulae, Cordceps militaris, Peach kernel, Agricus blazei composition.
2. the Chinese medicine preparation for the treatment of diabetic nephropathy according to claim 1, it is characterised in that:By weight, the jade Rice must account for 2-5%, the Morinda officinalis accounts for 2-5%, the rhizoma imperatae accounts for 4-8%, the monkshood accounts for 3-6%, the pueraria lobata accounts for 1-2%, institute State that Chinese cassia tree accounts for 1-3%, the silkworm chrysalis accounts for 1-3%, the Radix Ophiopogonis accounts for 1-2%, the radix scrophulariae accounts for 2-4%, the root of Chinese trichosanthes accounts for 3-5%, institute State that Radix Angelicae Sinensis accounts for 3-5%, the Radix Rehmanniae accounts for 1-2%, the tuber of pinellia accounts for 3-5%, the rhizoma anemarrhenae accounts for 1-2%, the Poria cocos accounts for 1-3%, described Radix achyranthis bidentatae accounts for 5-8%, the radix cyathulae accounts for 5-8%, the Cordceps militaris accounts for 20-25%, the peach kernel accounts for 8-10%, the Agricus blazei accounts for 8-15%。
3. the Chinese medicine preparation for the treatment of diabetic nephropathy according to claim 1, it is characterised in that:By weight, per 100g Containing the corn stigma 3g, the Morinda officinalis 3g, the rhizoma imperatae 5g, the monkshood 5g, the pueraria lobata 1.5g, the Chinese cassia tree 2.5g, the silkworm chrysalis 3g, the Radix Ophiopogonis 1.5g, the radix scrophulariae 3.5g, the root of Chinese trichosanthes 5g, the Radix Angelicae Sinensis 4g, the Radix Rehmanniae 1.5g, the tuber of pinellia 3.5g, the rhizoma anemarrhenae 1.5g, the Poria cocos 2.5g, the radix achyranthis bidentatae 8g, the radix cyathulae 8g, the north Cordyceps sinensis 20g, the peach kernel 8g, the Agricus blazei 10g.
4. the Chinese medicine preparation for the treatment of diabetic nephropathy according to claim 1, it is characterised in that:All medicaments of each component are mixed After conjunction, 3 times of medicine gross weight are added water to, impregnate 50min, 10min is heated at 90-100 DEG C, then reduce temperature to 50-60 DEG C, 10min is kept the temperature, then increase temperature to 90-100 DEG C, continue to heat 5min, be cooled to 50-60 DEG C again, keeps the temperature 5min, it is cold But, it filters, removes slag, oral solution is made after packaging and forms.
5. the Chinese medicine preparation for the treatment of diabetic nephropathy according to claim 4, it is characterised in that:The oral solution heating is steamed Hair is condensed into paste medicinal extract, dries pulverizing, and tablet or pill is made in pelletizing press sheet.
6. the Chinese medicine preparation for the treatment of diabetic nephropathy according to claim 5, it is characterised in that:The medicinal extract dries pulverizing Granule is made.
CN201810411479.6A 2018-05-02 2018-05-02 A kind of Chinese medicine preparation for treating diabetic nephropathy Pending CN108392583A (en)

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Publication number Priority date Publication date Assignee Title
CN109091631A (en) * 2018-09-06 2018-12-28 郑州大学第附属医院 The Radix Angelicae Sinensis Astragalus in Treating reagent and preparation method for treating early diabetic nephropathy

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CN104510949A (en) * 2013-10-07 2015-04-15 青岛联合创新技术服务平台有限公司 Traditional Chinese medicine formula treating diabetic nephropathy
CN107865950A (en) * 2016-09-27 2018-04-03 青岛大嘴网络技术有限公司 A kind of cordyceps sinensis composition for controlling diabetes

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CN104510949A (en) * 2013-10-07 2015-04-15 青岛联合创新技术服务平台有限公司 Traditional Chinese medicine formula treating diabetic nephropathy
CN107865950A (en) * 2016-09-27 2018-04-03 青岛大嘴网络技术有限公司 A kind of cordyceps sinensis composition for controlling diabetes

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Title
孙步策: "中西医结合治疗糖尿病肾病10例", 《内蒙古中医药》 *
张莹雯: "复方糖肾平安汤辨证加减治疗糖尿病肾病56例", 《四川中医》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109091631A (en) * 2018-09-06 2018-12-28 郑州大学第附属医院 The Radix Angelicae Sinensis Astragalus in Treating reagent and preparation method for treating early diabetic nephropathy

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Application publication date: 20180814