CN107242994B - Body wash capable of relieving ache and preparation method thereof - Google Patents
Body wash capable of relieving ache and preparation method thereof Download PDFInfo
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Abstract
The invention relates to the field of daily chemical articles, and provides a body wash capable of relieving ache and a preparation method thereof. The bath lotion comprises the following components in parts by weight: 5-10 parts of cocamide betaine, 4-6 parts of sodium lauryl glutamate, 5-10 parts of ache relieving microemulsion, 4-6 parts of saponin, 1-5 parts of plant essential oil, 0.5-1.5 parts of camphorwood particles, 1-3 parts of an antibacterial agent, 0-10 parts of a pH regulator, 5-10 parts of glycerol and 55-65 parts of water. The bath cream contains the ache relieving microemulsion which can relieve ache, and is easy to be absorbed by skin, thereby having quick effect. In addition, the shower cream also contains an antibacterial agent with high antibacterial activity and good mildness, and can not cause excessive damage to cells.
Description
Technical Field
The invention relates to the field of daily chemical articles, in particular to a body wash capable of relieving ache and a preparation method thereof.
Background
In order to meet the requirements of consumers and avoid product homogenization, various functional body lotions, such as antibacterial, fragrance, mosquito-proof, toxin expelling, skin moistening and the like, are sold on the market at present.
Patent CN201210351635.7 discloses a pulling-resistant body wash, which is prepared from sodium dodecyl benzene sulfonate, isopropanol, trimethanolamine, sodium lauryl sulfate, fatty alcohol-polyoxyethylene ether and deionized water, wherein the weight parts of the components are as follows: 12-15 parts of sodium dodecyl benzene sulfonate; isopropyl alcohol: 18-20 parts; trimethanolamine: 10-15 parts; sodium lauryl sulfate: 8-10 parts; fatty alcohol polyoxyethylene ether: 18-22 parts; deionized water: 30-40 parts.
The anti-pulling shower gel is convenient to use, can effectively remove dirt on a body, and has the effect of relieving pain on a pulled part. But the disadvantages are: for some actives that can relieve pain, the skin does not absorb it as well.
Patent CN201010220126.1 discloses an environment-friendly antibacterial shower gel, which is composed of the following components in parts by weight: 6-10 parts of cocamidopropyl betaine; sorbitan laurate PEG-806-10 parts; 76-10 parts of polyquaternium; 8-10 parts of sodium dodecyl sulfate; 1-2 parts of polyvinyl alcohol; 0.2-1 part of diethanolamine; 0.5-1.5 parts of glycerol; 0.01-0.03 part of Yujiexin; 0.01-0.03 part of benzisothiazolinone; 50-75 parts of water.
In the invention, polyquaternium, triclosan, benzisothiazolinone and other substances are added into the shower gel, and although the shower gel has excellent antibacterial property, the substances are chemically synthesized into the antibacterial property and have side effects on human bodies. There are also many body lotions containing natural antibacterial ingredients, which, although they are substantially harmless to the skin, have the disadvantage of having a poor antibacterial activity compared to chemical antibacterial agents. But has certain side effect on skin cells if the chemical antibacterial agent is directly added.
Disclosure of Invention
In order to solve the technical problems, the invention provides a body wash capable of relieving ache and a preparation method thereof. The bath cream contains the ache relieving microemulsion which can relieve ache, and is easy to be absorbed by skin, thereby having quick effect. In addition, the shower cream also contains an antibacterial agent with high antibacterial activity and good mildness, and can not cause excessive damage to cells.
In order to achieve the aim, the invention provides a body wash for relieving ache, which comprises the following components in parts by weight:
5-10 parts of cocoamido betaine,
4-6 parts of sodium lauryl glutamate,
5-10 parts of a pain relieving microemulsion,
4-6 parts of saponin, namely,
1-5 parts of plant essential oil
0.5 to 1.5 portions of camphorwood particles,
1-3 parts of an antibacterial agent,
0-10 parts of a pH regulator,
5-10 parts of glycerol, namely,
55-65 parts of water.
In the formula of the invention, besides the common basic formula of the bath cream, the acid pain relieving microemulsion is also contained and coated with the substance with the function of relieving pain. The saponin has strong surface activity, strong detergency, and anti-inflammatory and analgesic effects. The plant essential oil can relieve mental stress. The camphorwood particles have fragrance and have refreshing effect. The granular camphorwood particles rub the skin when bathing, so that the effects of decontaminating and removing cutin are achieved; on the other hand, the massage device can also play a role in massaging the skin, and relieve pain physically. Meanwhile, the formula of the invention also comprises an antibacterial agent, which can sterilize the wound part of the skin and prevent the secondary infection of the wound.
Preferably, the plant essential oil is at least one selected from rose essential oil, mint essential oil, tea tree essential oil, lavender essential oil and camphor essential oil.
Preferably, the camphorwood particles are pretreated by: adding water into the camphorwood particles, then performing pressure cooking for 3-5h, filtering and drying to obtain the finished product.
The structure of the camphorwood particles subjected to pressure cooking is loosened, the texture becomes softer, the skin is less damaged in the friction process, and the texture liquid becomes looser due to the loosening, so that the camphorwood particles have better adsorbability and can absorb sweat, impurities and the like.
Preferably, the particle size of the camphorwood particles is in the micron order.
Preferably, the sore pain relieving microemulsion is an aqueous-in-oil-in-water microemulsion comprising ginger extract and hyaluronic acid.
The rhizoma Zingiberis recens extract and hyaluronic acid can be absorbed for relieving pain.
Preferably, the preparation method of the ache relieving microemulsion comprises the following steps:
dissolving rhizoma Zingiberis recens extract and hyaluronic acid in water, adding surfactant, and stirring to obtain water phase solution; adding the aqueous solution into tea tree oil containing rhizoma Zingiberis recens extract, hyaluronic acid and surfactant, and stirring to obtain water-in-oil granule; and finally adding the water-in-oil particles into water containing ginger extract, hyaluronic acid and surfactant, fully stirring and separating to obtain the water-in-oil-in-water ache relieving microemulsion.
The ache-relieving microemulsion prepared by the method has a water phase-oil phase and-water phase three-layer coating structure, and each layer of water/oil phase contains active substances (ginger extract, hyaluronic acid), so that the ache-relieving microemulsion has the advantages that a plurality of hydrophilic substances (cell sap, cytoplasm and the like) and lipophilic substances (cell membranes and the like) in skin cells can permeate into the skin cells layer by layer when in use, and the water phase layer substances are dissolved in the hydrophilic substances when in water, so that the active substances are released; when encountering lipophilic substances, the oil phase layer substances thereof dissolve therein, also releasing the active substances. Therefore, it can sufficiently and rapidly permeate into skin cells, promote absorption and take effect. In addition, the tea tree oil is selected as the oil phase material, and the tea tree oil also has good antioxidant and antibacterial effects.
Preferably, the surfactant is sodium dodecylbenzene sulfonate or ammonium lauryl sulfate.
Preferably, the antimicrobial agent is a triblock copolymer of hydroxyl-terminated polycaprolactone, itaconic acid, and 2- (dimethylamino) ethyl methacrylate.
Preferably, the preparation method of the triblock copolymer of polycaprolactone containing hydroxyl at the terminal, itaconic acid and 2- (dimethylamino) ethyl methacrylate comprises the following steps:
dissolving 8-10 parts by weight of polycaprolactone containing hydroxyl at a terminal group in chloroform, dropwise adding 0.2-0.4 part by weight of bromoisobutyryl bromide under the condition of nitrogen atmosphere and 0-5 ℃, reacting for 16-20h, and adding a reaction product into anhydrous methanol for precipitation to obtain modified polycaprolactone; dissolving modified polycaprolactone in dimethyl sulfoxide, adding 0.2-0.4 part by weight of cuprous bromide, adding 8-12 parts by weight of itaconic acid in nitrogen atmosphere, carrying out polymerization reaction at 75-85 ℃ for 8-12h, then adding 10-15 parts by weight of 2- (dimethylamino) ethyl methacrylate, carrying out thermal insulation polymerization reaction for 4-6h, and precipitating and filtering a reaction product to obtain the triblock copolymer.
When a wound on the skin is infected with bacteria, the infected cells secrete acidic substances such as lactic acid, so that the wound is weakly acidic. When the skin is not infected or the infected area heals, it returns to its original neutral state. According to this characteristic, the present inventors have produced the above-mentioned antibacterial agent. The antibacterial agent is obtained by copolymerizing three monomers (polycaprolactone with hydroxyl at the terminal group, itaconic acid and 2- (dimethylamino) ethyl methacrylate), wherein the 2- (dimethylamino) ethyl methacrylate has antibacterial property due to the quaternary ammonium salt functional group. The above copolymer had the following characteristics: under a weak acid environment, the chain segment of the itaconic acid is neutral, the polycaprolactone and 2- (dimethylamino) ethyl methacrylate) chain segments at the two ends of the itaconic acid are stretched, the whole copolymer is positive, and at the moment, the copolymer has antibacterial property. In a neutral environment, the middle chain segment of the itaconic acid is negatively charged, and the polycaprolactone and 2- (dimethylamino) ethyl methacrylate) chain segments at the two ends of the itaconic acid are positively charged, so that the antibacterial property is greatly reduced under the electrostatic action. Compared with other cosmetology antibacterial agents, the antibacterial agent of the invention can show better antibacterial property only after the wound is infected with weak acid, and has no antibacterial property to the skin which is not infected or after the infection is cleared. Because the antibacterial agent can also cause damage to human cells while resisting bacteria, the antibacterial agent of the invention can rapidly avoid antibacterial action after bacteria are killed, and can not cause excessive damage to human cells.
Preferably, the antimicrobial agent is a nano-sized particle.
A preparation method of the bath lotion for relieving ache comprises the following steps:
1) preparing a pain relieving microemulsion;
2) adding camphorwood particles into plant essential oil for soaking;
3) adding cocoamido betaine, sodium lauryl glutamate, ache relieving microemulsion, saponin and an antibacterial agent into a mixed solution of glycerol and water, stirring uniformly, adding a mixture of plant essential oil and camphorwood particles, and stirring uniformly to obtain a semi-finished product;
4) adding pH regulator to regulate pH value of the semi-finished product to 7-8 to obtain the final product.
In the step 2), the camphorwood particles are firstly soaked in the plant essential oil, and because the camphorwood particles are subjected to pressure cooking and defibering treatment, the camphorwood particles have better adsorbability, and can adsorb the essential oil by soaking in the plant essential oil, thereby playing a role of slow release.
The invention has the following beneficial effects: the bath cream contains the ache relieving microemulsion which can relieve ache, and is easy to be absorbed by skin, thereby having quick effect. In addition, the shower cream also contains an antibacterial agent with high antibacterial activity and good mildness, and can not cause excessive damage to cells.
Detailed Description
The following is a detailed description of embodiments of the invention, but the invention can be implemented in many different ways, as defined and covered by the claims.
Example 1
The bath lotion for relieving ache comprises the following components in parts by weight:
8 parts of coco amido betaine,
5 parts of sodium lauryl glutamate (DON),
7 parts of a microemulsion for relieving ache and 7 parts of,
5 parts of saponin, namely 5 parts of saponin,
3 parts of plant essential oil (rose essential oil)
1 part of micron-sized camphorwood particles,
2 parts of nano-scale antibacterial agent,
a proper amount of pH regulator is added,
7 parts of glycerol, namely adding 7 parts of glycerol,
60 parts of water.
Wherein, the camphorwood particles are pretreated: adding water into the camphorwood particles, then performing pressure cooking for 4 hours, filtering and drying to obtain the finished product.
The ache relieving microemulsion is an aqueous-in-oil-in-aqueous microemulsion containing ginger extract and hyaluronic acid, and the preparation method comprises the following steps: dissolving rhizoma Zingiberis recens extract and hyaluronic acid in water, adding surfactant (sodium dodecyl benzene sulfonate), and stirring to obtain water phase solution; adding the aqueous solution into tea tree oil containing rhizoma Zingiberis recens extract, hyaluronic acid and surfactant (sodium dodecylbenzenesulfonate), and stirring to obtain water-in-oil granule; and finally adding the water-in-oil particles into water containing ginger extract, hyaluronic acid and a surfactant (sodium dodecyl benzene sulfonate), fully stirring and separating to obtain the water-in-oil-in-water ache relieving microemulsion.
The nano-scale antibacterial agent particles are triblock copolymers of polycaprolactone with hydroxyl at the terminal, itaconic acid and 2- (dimethylamino) ethyl methacrylate, and the preparation method comprises the following steps: dissolving 9 parts by weight of polycaprolactone containing hydroxyl at a terminal group in chloroform, dropwise adding 0.3 part by weight of bromoisobutyryl bromide into the chloroform at 2 ℃ in a nitrogen atmosphere, reacting for 18 hours, and adding a reaction product into anhydrous methanol for precipitation to obtain modified polycaprolactone; dissolving modified polycaprolactone in dimethyl sulfoxide, adding 0.3 part by weight of cuprous bromide, adding 10 parts by weight of itaconic acid in nitrogen atmosphere, carrying out polymerization reaction for 10 hours at 80 ℃, then adding 12 parts by weight of 2- (dimethylamino) ethyl methacrylate, carrying out thermal polymerization reaction for 5 hours, and precipitating and filtering a reaction product to obtain the triblock copolymer.
The preparation method of the body wash for relieving ache comprises the following steps:
1) the ache relieving microemulsion is prepared.
2) Adding the camphorwood particles into the plant essential oil for soaking.
3) Adding cocoamido betaine, sodium lauryl glutamate, ache relieving microemulsion, saponin and an antibacterial agent into a mixed solution of glycerol and water, stirring uniformly, adding a mixture of plant essential oil and camphorwood particles, and stirring uniformly to obtain a semi-finished product.
4) Adding pH regulator to regulate pH value of the semi-finished product to 7 to obtain the final product.
Example 2
The bath lotion for relieving ache comprises the following components in parts by weight:
5 parts of coco amido betaine,
4 parts of sodium lauryl glutamate (DOG),
5 parts of a microemulsion for relieving ache and 5 parts of a microemulsion,
4 parts of saponin, namely 4 parts of saponin,
plant essential oil (peppermint essential oil) 1 part
0.5 part of micron-sized camphorwood particles,
1 part of nano-scale antibacterial agent, namely,
a proper amount of pH regulator is added,
5 parts of glycerol, namely adding 5 parts of glycerol,
55 parts of water.
Wherein, the camphorwood particles are pretreated: adding water into the camphorwood particles, then performing pressure cooking for 3 hours, filtering and drying to obtain the finished product.
The ache relieving microemulsion is an aqueous-in-oil-in-aqueous microemulsion containing ginger extract and hyaluronic acid, and the preparation method comprises the following steps: dissolving rhizoma Zingiberis recens extract and hyaluronic acid in water, adding surfactant (ammonium laurylsulfate), and stirring to obtain water phase solution; adding the aqueous solution into tea tree oil containing rhizoma Zingiberis recens extract, hyaluronic acid and surfactant (ammonium laurylsulfate), and stirring to obtain water-in-oil granule; and finally adding the water-in-oil particles into water containing ginger extract, hyaluronic acid and a surfactant (ammonium dodecyl sulfate), fully stirring and separating to obtain the water-in-oil-in-water ache relieving microemulsion.
The nano-scale antibacterial agent particles are triblock copolymers of polycaprolactone with hydroxyl at the terminal, itaconic acid and 2- (dimethylamino) ethyl methacrylate, and the preparation method comprises the following steps: dissolving 8 parts by weight of polycaprolactone containing hydroxyl at the terminal group in chloroform, dropwise adding 0.2 part by weight of bromoisobutyryl bromide into the chloroform at 0 ℃ in a nitrogen atmosphere, reacting for 16 hours, and adding a reaction product into anhydrous methanol for precipitation to obtain modified polycaprolactone; dissolving modified polycaprolactone in dimethyl sulfoxide, adding 0.2 part by weight of cuprous bromide, adding 8 parts by weight of itaconic acid in a nitrogen atmosphere, carrying out polymerization reaction for 12 hours at 75 ℃, then adding 10 parts by weight of 2- (dimethylamino) ethyl methacrylate, carrying out thermal polymerization for 6 hours, and precipitating and filtering a reaction product to obtain the triblock copolymer.
The preparation method of the body wash for relieving ache comprises the following steps:
1) the ache relieving microemulsion is prepared.
2) Adding the camphorwood particles into the plant essential oil for soaking.
3) Adding cocoamido betaine, sodium lauryl glutamate, ache relieving microemulsion, saponin and an antibacterial agent into a mixed solution of glycerol and water, stirring uniformly, adding a mixture of plant essential oil and camphorwood particles, and stirring uniformly to obtain a semi-finished product.
4) Adding pH regulator to regulate pH value of the semi-finished product to 8 to obtain the final product.
Example 3
The bath lotion for relieving ache comprises the following components in parts by weight:
10 parts of coco amido betaine,
6 parts of sodium lauryl glutamate (DOG),
10 parts of microemulsion for relieving ache and 10 parts of,
6 parts of saponin, namely 6 parts of saponin,
5 parts of plant essential oil (tea tree essential oil)
1.5 parts of micron-sized camphorwood particles,
3 parts of nano-scale antibacterial agent, namely,
a proper amount of pH regulator is added,
10 parts of glycerol, namely 10 parts of glycerol,
and 65 parts of water.
Wherein, the camphorwood particles are pretreated: adding water into the camphorwood particles, then performing pressure cooking for 5 hours, filtering and drying to obtain the finished product.
The ache relieving microemulsion is an aqueous-in-oil-in-aqueous microemulsion containing ginger extract and hyaluronic acid, and the preparation method comprises the following steps: dissolving rhizoma Zingiberis recens extract and hyaluronic acid in water, adding surfactant (sodium dodecyl benzene sulfonate), and stirring to obtain water phase solution; adding the aqueous solution into tea tree oil containing rhizoma Zingiberis recens extract, hyaluronic acid and surfactant (sodium dodecylbenzenesulfonate), and stirring to obtain water-in-oil granule; and finally adding the water-in-oil particles into water containing ginger extract, hyaluronic acid and a surfactant (sodium dodecyl benzene sulfonate), fully stirring and separating to obtain the water-in-oil-in-water ache relieving microemulsion.
The nano-scale antibacterial agent particles are triblock copolymers of polycaprolactone with hydroxyl at the terminal, itaconic acid and 2- (dimethylamino) ethyl methacrylate, and the preparation method comprises the following steps: dissolving 10 parts by weight of polycaprolactone containing hydroxyl at a terminal group in chloroform, dropwise adding 0.4 part by weight of bromoisobutyryl bromide into the chloroform at 5 ℃ in a nitrogen atmosphere, reacting for 20 hours, and adding a reaction product into anhydrous methanol for precipitation to obtain modified polycaprolactone; dissolving modified polycaprolactone in dimethyl sulfoxide, adding 0.4 part by weight of cuprous bromide, adding 12 parts by weight of itaconic acid in nitrogen atmosphere, carrying out polymerization reaction for 8 hours at 85 ℃, then adding 15 parts by weight of 2- (dimethylamino) ethyl methacrylate, carrying out thermal polymerization reaction for 6 hours, and precipitating and filtering a reaction product to obtain the triblock copolymer.
The preparation method of the body wash for relieving ache comprises the following steps:
1) the ache relieving microemulsion is prepared.
2) Adding the camphorwood particles into the plant essential oil for soaking.
3) Adding cocoamido betaine, sodium lauryl glutamate, ache relieving microemulsion, saponin and an antibacterial agent into a mixed solution of glycerol and water, stirring uniformly, adding a mixture of plant essential oil and camphorwood particles, and stirring uniformly to obtain a semi-finished product.
4) Adding pH regulator to regulate pH value of the semi-finished product to 7.5 to obtain the final product.
Example 4
The bath lotion for relieving ache comprises the following components in parts by weight:
6 parts of coco amido betaine,
5 parts of sodium lauryl glutamate (DON),
8 parts of a microemulsion for relieving ache and 8 parts of,
4 parts of saponin, namely 4 parts of saponin,
2 parts of plant essential oil (lavender essential oil)
1 part of micron-sized camphorwood particles,
2 parts of nano-scale antibacterial agent,
a proper amount of pH regulator is added,
6 parts of glycerol, namely 6 parts of glycerol,
58 parts of water.
Wherein, the camphorwood particles are pretreated: adding water into the camphorwood particles, then performing pressure cooking for 3.5 hours, filtering and drying to obtain the finished product.
The ache relieving microemulsion is an aqueous-in-oil-in-aqueous microemulsion containing ginger extract and hyaluronic acid, and the preparation method comprises the following steps: dissolving rhizoma Zingiberis recens extract and hyaluronic acid in water, adding surfactant (sodium dodecyl benzene sulfonate), and stirring to obtain water phase solution; adding the aqueous solution into tea tree oil containing rhizoma Zingiberis recens extract, hyaluronic acid and surfactant (sodium dodecylbenzenesulfonate), and stirring to obtain water-in-oil granule; and finally adding the water-in-oil particles into water containing ginger extract, hyaluronic acid and a surfactant (sodium dodecyl benzene sulfonate), fully stirring and separating to obtain the water-in-oil-in-water ache relieving microemulsion.
The nano-scale antibacterial agent particles are triblock copolymers of polycaprolactone with hydroxyl at the terminal, itaconic acid and 2- (dimethylamino) ethyl methacrylate, and the preparation method comprises the following steps: dissolving 8 parts by weight of polycaprolactone containing hydroxyl at the terminal group in chloroform, dropwise adding 0.3 part by weight of bromoisobutyryl bromide into the chloroform at 0 ℃ in a nitrogen atmosphere, reacting for 18 hours, and adding a reaction product into anhydrous methanol for precipitation to obtain modified polycaprolactone; dissolving modified polycaprolactone in dimethyl sulfoxide, adding 0.3 part by weight of cuprous bromide, adding 8-12 parts by weight of itaconic acid in nitrogen atmosphere, carrying out polymerization reaction at 80 ℃ for 9 hours, then adding 14 parts by weight of 2- (dimethylamino) ethyl methacrylate, carrying out thermal polymerization reaction for 5.5 hours, and precipitating and filtering a reaction product to obtain the triblock copolymer.
The preparation method of the body wash for relieving ache comprises the following steps:
1) the ache relieving microemulsion is prepared.
2) Adding the camphorwood particles into the plant essential oil for soaking.
3) Adding cocoamido betaine, sodium lauryl glutamate, ache relieving microemulsion, saponin and an antibacterial agent into a mixed solution of glycerol and water, stirring uniformly, adding a mixture of plant essential oil and camphorwood particles, and stirring uniformly to obtain a semi-finished product.
4) Adding pH regulator to regulate pH value of the semi-finished product to 7.5 to obtain the final product.
Example 5
The bath lotion for relieving ache comprises the following components in parts by weight:
8 parts of coco amido betaine,
4 parts of sodium lauryl glutamate (DOG),
6 parts of a microemulsion for relieving ache and 6 parts of,
6 parts of saponin, namely 6 parts of saponin,
2 parts of plant essential oil (camphor essential oil)
1 part of micron-sized camphorwood particles,
3 parts of nano-scale antibacterial agent, namely,
a proper amount of pH regulator is added,
8 parts of glycerol, namely 8 parts of glycerol,
60 parts of water.
Wherein, the camphorwood particles are pretreated: adding water into the camphorwood particles, then performing pressure cooking for 4.5 hours, filtering and drying to obtain the finished product.
The ache relieving microemulsion is an aqueous-in-oil-in-aqueous microemulsion containing ginger extract and hyaluronic acid, and the preparation method comprises the following steps: dissolving rhizoma Zingiberis recens extract and hyaluronic acid in water, adding surfactant (ammonium laurylsulfate), and stirring to obtain water phase solution; adding the aqueous solution into tea tree oil containing rhizoma Zingiberis recens extract, hyaluronic acid and surfactant (ammonium laurylsulfate), and stirring to obtain water-in-oil granule; and finally adding the water-in-oil particles into water containing ginger extract, hyaluronic acid and a surfactant (ammonium dodecyl sulfate), fully stirring and separating to obtain the water-in-oil-in-water ache relieving microemulsion.
The nano-scale antibacterial agent particles are triblock copolymers of polycaprolactone with hydroxyl at the terminal, itaconic acid and 2- (dimethylamino) ethyl methacrylate, and the preparation method comprises the following steps: dissolving 8 parts by weight of polycaprolactone containing hydroxyl at a terminal group in chloroform, dropwise adding 0.2 part by weight of bromoisobutyryl bromide into the chloroform at 1 ℃ in a nitrogen atmosphere, reacting for 16 hours, and adding a reaction product into anhydrous methanol for precipitation to obtain modified polycaprolactone; dissolving modified polycaprolactone in dimethyl sulfoxide, adding 0.2 part by weight of cuprous bromide, adding 8 parts by weight of itaconic acid in nitrogen atmosphere, carrying out polymerization reaction at 80 ℃ for 9 hours, then adding 12 parts by weight of 2- (dimethylamino) ethyl methacrylate, carrying out thermal polymerization reaction for 4.5 hours, and precipitating and filtering a reaction product to obtain the triblock copolymer.
The preparation method of the body wash for relieving ache comprises the following steps:
1) the ache relieving microemulsion is prepared.
2) Adding the camphorwood particles into the plant essential oil for soaking.
3) Adding cocoamido betaine, sodium lauryl glutamate, ache relieving microemulsion, saponin and an antibacterial agent into a mixed solution of glycerol and water, stirring uniformly, adding a mixture of plant essential oil and camphorwood particles, and stirring uniformly to obtain a semi-finished product.
4) Adding pH regulator to regulate pH value of the semi-finished product to 7 to obtain the final product.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (7)
1. The body wash capable of relieving ache is characterized by comprising the following components in parts by weight:
5-10 parts of cocoamido betaine,
4-6 parts of sodium lauryl glutamate,
5-10 parts of a pain relieving microemulsion,
4-6 parts of saponin, namely,
1-5 parts of plant essential oil
0.5 to 1.5 portions of camphorwood particles,
1-3 parts of an antibacterial agent,
0-10 parts of a pH regulator,
5-10 parts of glycerol, namely,
55-65 parts of water;
the camphorwood particles are pretreated: adding water into camphorwood particles, then performing pressure cooking for 3-5h, filtering and drying to obtain a finished product;
the ache relieving microemulsion is an aqueous-in-oil-in-water microemulsion containing ginger extract and hyaluronic acid; the preparation method of the ache relieving microemulsion comprises the following steps: dissolving rhizoma Zingiberis recens extract and hyaluronic acid in water, adding surfactant, and stirring to obtain water phase solution; adding the aqueous solution into tea tree oil containing rhizoma Zingiberis recens extract, hyaluronic acid and surfactant, and stirring to obtain water-in-oil granule; and finally adding the water-in-oil particles into water containing ginger extract, hyaluronic acid and surfactant, fully stirring and separating to obtain the water-in-oil-in-water ache relieving microemulsion.
2. The body wash for relieving soreness according to claim 1, wherein the plant essential oil is at least one selected from rose essential oil, mint essential oil, tea tree essential oil, lavender essential oil, and camphor essential oil.
3. The acid pain relieving body wash of claim 1, wherein the camphorwood particles have a micron size.
4. The body wash for relieving soreness of claim 1, wherein the surfactant is sodium dodecylbenzene sulfonate or ammonium dodecylsulfate.
5. A soothing souring bath lotion as claimed in claim 1 wherein said antimicrobial agent is a triblock copolymer of hydroxyl terminated polycaprolactone, itaconic acid and 2- (dimethylamino) ethyl methacrylate.
6. A soothing souring bath lotion as claimed in claim 5 wherein said triblock copolymer of hydroxy terminated polycaprolactone, itaconic acid and 2- (dimethylamino) ethyl methacrylate is prepared by:
dissolving 8-10 parts by weight of polycaprolactone containing hydroxyl at a terminal group in chloroform, dropwise adding 0.2-0.4 part by weight of bromoisobutyryl bromide under the condition of nitrogen atmosphere and 0-5 ℃, reacting for 16-20h, and adding a reaction product into anhydrous methanol for precipitation to obtain modified polycaprolactone; dissolving modified polycaprolactone in dimethyl sulfoxide, adding 0.2-0.4 part by weight of cuprous bromide, adding 8-12 parts by weight of itaconic acid in nitrogen atmosphere, carrying out polymerization reaction at 75-85 ℃ for 8-12h, then adding 10-15 parts by weight of 2- (dimethylamino) ethyl methacrylate, carrying out thermal insulation polymerization reaction for 4-6h, and precipitating and filtering a reaction product to obtain the triblock copolymer.
7. A process for preparing a soothing soul according to any one of claims 1 to 6, characterized in that it comprises the following steps:
1) preparing a pain relieving microemulsion;
2) adding camphorwood particles into plant essential oil for soaking;
3) adding cocoamido betaine, sodium lauryl glutamate, ache relieving microemulsion, saponin and an antibacterial agent into a mixed solution of glycerol and water, stirring uniformly, adding a mixture of plant essential oil and camphorwood particles, and stirring uniformly to obtain a semi-finished product;
4) adding pH regulator to regulate pH value of the semi-finished product to 7-8 to obtain the final product.
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| CN103230348B (en) * | 2013-03-13 | 2014-10-08 | 李慧娟 | Yao drug bath lotion and preparation method thereof |
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