CN107233418A - A kind of composition, preparation method and its application method for being used to prevent and treat porcine hyperthermia - Google Patents
A kind of composition, preparation method and its application method for being used to prevent and treat porcine hyperthermia Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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Abstract
The invention belongs to livestock and poultry cultivation technical field, there is provided a kind of composition, preparation method and its application method for being used to prevent and treat porcine hyperthermia, including following components:13~30 parts of radix bupleuri, 10~27 parts of sweet wormwood, 12~32 parts of gypsum, 10~30 parts of golden cypress, 6~17 parts of amylase, 5~18 parts of plant lactic acid.The raw material that composition provided in an embodiment of the present invention is used is cheap and easy to get and stable storing is high, porcine hyperthermia is prevented and treated by the way of Chinese medicine combination amylase and the mixing of vegetalitas lactic acid bacteria, with while porcine hyperthermia is prevented and treated, improve the immunity of its body, the incidence of porcine hyperthermia can be reduced and the recovery of pig can be promoted to cure, and do not produce drug resistance and drug-fast advantage.
Description
Technical field
The invention belongs to livestock and poultry cultivation technical field, more particularly to a kind of it be used to prevent and treat the composition of porcine hyperthermia, prepare
Method and its application method.
Background technology
Porcine hyperthermia is swine high fever syndrome, is a kind of morbidity and mortality higher disease, and sick pig is clinical main
Body temperature rise, depressed spirit, poor appetite or useless exhausted are shown as, has difficulty in breathing, breathe, part pig is with rubefaction purpling etc.
Symptom, a small number of pores have blutpunkte.Cause of disease is mainly a variety of viruses and bacterium, the mixed infection and scabies secondary infection of parasite, bag
Include CSFV (HCV), porcine reproductive and respiratory syndrome virus (PRRSV), swine influenza virus (SIV), pseudorabies virus
(ADV), porcine circovirus 2 type (PCV-II) and actinobacillus pleuropneumoniae (APP), Streptococcus suis belong to 2 types (SS-II), pair
Haemophilus suis disease (HP), pasteurella multocida (PM), porcine mycoplasmal pneumonia (MH), toxoplasm, eperythrozoon, hog cholera
The mixed infection of the bacteriums such as salmonella (SC).
Because the cause of disease is complicated, the mixed infection of generally many cause of diseases, clinically more difficult control, prevention effect is often not
Ideal, causes swinery slow-growing or stagnates, invalid pig and dead pig are increased, feed efficiency, the speed of growth and swinery are whole
The uniformity reduction of body, cost accounting increase makes Swine Production suffer serious loss.
In the prior art, generally using preventing and treating porcine hyperthermia such as antibiotics, but antibiotic preventing and treating is easily
The homeostasis of pig is destroyed, and the effect of preventing and treating is not good, and also long-term use antibiotic easily produces drug resistance.
The content of the invention
The embodiment of the present invention provides a kind of composition for being used to prevent and treat porcine hyperthermia, it is intended to solve antibiotic in the prior art
Preventing and treating is easily destroyed the homeostasis of pig, and the effect of preventing and treating is not good, and long-term use antibiotic easily produces drug resistance
The problem of.
The embodiment of the present invention is achieved in that a kind of composition for being used to prevent and treat porcine hyperthermia, by weight, the combination
Thing includes:5~30 parts of radix bupleuri, 3~25 parts of sweet wormwood, 8~35 parts of gypsum, 6~30 parts of golden cypress, 4~20 parts of amylase, vegetalitas breast
Sour 5~20 parts of bacterium.
The embodiment of the present invention additionally provides the above-mentioned preparation method for being used to prevent and treat the composition of porcine hyperthermia, and this method includes
Following steps:
By radix bupleuri, sweet wormwood, gypsum, golden cypress, amylase and the mixing of vegetalitas lactic acid bacteria are placed in closed fermenter;
Water vapour is passed through toward the closed fermenter, and reaches the relative humidity in the closed fermenter
More than 80%;
It is under conditions of 30 DEG C~45 DEG C after aerobic fermentation 40~55 hours in temperature, then to carry out anaerobic fermentation 72~85 small
Shi Hou;
Composition after the anaerobic fermentation is dried.
The embodiment of the present invention additionally provides the above-mentioned application method for being used to prevent and treat the composition of porcine hyperthermia, by the combination
Thing is 1 by weight with feed:(400~600), which are added in feed, to be used.
The source of various raw materials in above-mentioned composition, effect and composition are described as follows:
Radix bupleuri, be《Chinese Pharmacopoeia》The herbal medicine included, medicinal part is the drying of umbelliferae bupleurum or radix bupleuri scorzoneraefolii
Root, is conventional diaphoretic medicine.It is bitter in taste, be slightly cold, Return liver, gallbladder channel;With antipyretic, calm, analgesia, anti-inflammatory, antipathogen, reconciliation
It is soothing the liver in table, the effects such as rising Yang;It is mainly used in cold, fever, fevers and chills alternate, distending pain in the chest and hypochondrium, irregular menstruation, sub-official prolapses take off
Anus etc..
Sweet wormwood, Chinese medicine sweet wormwood is the dry aerial parts of feverfew sweet wormwood.Nature and flavor bitter;Micro-pungent;It is cold in nature, return liver warp,
Gallbladder channel;With antimalarial, antibacterial, anti parasitic is antipyretic, the effects such as being immunized;It is mainly used in heat-clearing;Relieving summer-heat;Except steaming;Preventing malaria.Main heat
Heat;Summer-heat and damp;Damp-warm syndrome;Fever due to yin deficiency;Malaria;Jaundice etc..
Gypsum, is monoclinic system mineral, is the hydrate that main chemical compositions are calcium sulfate.Nature and flavor are sweet, pungent, Great Cold, return
Lung, stomach;With antipyretic, anti-inflammatory, convergence is antiviral, the effects such as being immunized;Be mainly used in clearing heat-fire, relieving restlessness quench the thirst, outer sensible heat
Disease, hyperpyrexia polydipsia, dyspnea and cough due to lung-heat, stomach fire is high to contain, headache, toothache etc..Gypsum to normal body temperature without cooling effect, and to artificial
Heating animal has certain refrigeration function.
Golden cypress, is the dry bark of rutaceae wampee, bitter in taste, cold, returns kidney, bladder warp;With antibacterial (antibacterial
Active ingredient be jamaicin), antimycotic, antibechic, decompression, anti-trichomonal, anti-hepatitis, antiulcer, be immunized the effects such as;It is mainly used in
Heat-clearing and damp-drying drug, purging intense heat and detonicating, damp-heat dysentery, jaundice, with lower pruritus vulvae, puckery pain of heat gonorrhea, tinea pedis impotence is knitted, hectic fever due to yin labor heat, night sweat,
Seminal emission, sore swollen toxin, eczema wet sore etc..Stir-baked CORTEX PHELLODENDRI with salt solution nourishing Yin and falling fire, for fire excess from yin deficiency, night sweat hectic fever due to yin etc..
Amylase, is hydrolysis starch and the enzyme general name of glycogen, general action is in soluble starch, amylose, glycogen
Deng mainly hydrolyzing α-Isosorbide-5-Nitrae-glycosidic bond therein, α -1,6- glycosidic bonds.
Vegetalitas lactic acid bacteria:It is that separation screening comes out from traditional vegetalitas fermented food such as pickles, salted vegetables, thick broad-bean sauce
A class lactic acid bacteria.The lactobacillus products such as the Yoghourt that current people eat are mostly animality lactobacillus-fermenteds;But
Vegetalitas lactic acid bacteria is compared with animality lactic acid bacteria, and acidproof and bile tolerance ability is stronger, and can be in the uneven adverse circumstances of nutrition
Lower existence, so higher into human body intestinal canal survival rate, colonization ability is stronger.Therefore vegetalitas lactobacillus product is improving enteron aisle ring
In terms of border, raising body immunity advantageously.
The raw material that composition provided in an embodiment of the present invention is used is cheap and easy to get and stable storing is high, is combined using Chinese medicine
Amylase and the mode of vegetalitas lactic acid bacteria mixing prevent and treat porcine hyperthermia, with while porcine hyperthermia is prevented and treated, improve its machine
The immunity of body, it is possible to decrease the incidence of porcine hyperthermia simultaneously can promote the recovery of pig to cure, and do not produce drug resistance and the resistance to the action of a drug
Advantage.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments to the present invention
It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to
Limit the present invention.
The raw material that composition provided in an embodiment of the present invention is used is cheap and easy to get and stable storing is high, is combined using Chinese medicine
Amylase and the mode of vegetalitas lactic acid bacteria mixing prevent and treat porcine hyperthermia, with while porcine hyperthermia is prevented and treated, improve its machine
The immunity of body, it is possible to decrease the incidence of porcine hyperthermia simultaneously can promote the recovery of pig to cure, and do not produce drug resistance and the resistance to the action of a drug
Advantage.Meanwhile, the rational proportion of a variety of Chinese herbal medicines is more suitable for the taste of pig, can improve the appetite of pig.
The composition provided in an embodiment of the present invention for being used to prevent and treat porcine hyperthermia, by weight, said composition includes:Radix bupleuri
13~30 parts, 10~27 parts of sweet wormwood, 12~32 parts of gypsum, 10~30 parts of golden cypress, 6~17 parts of amylase, vegetalitas lactic acid bacteria 5~
18 parts.
It is preferred that, by weight, said composition includes:13~25 parts of radix bupleuri, 10~22 parts of sweet wormwood, 12~26 parts of gypsum,
10~25 parts of golden cypress, 6~13 parts of amylase, 5~14 parts of vegetalitas lactic acid bacteria.
It is preferred that, by weight, said composition includes:18~25 parts of radix bupleuri, 15~22 parts of sweet wormwood, 22~26 parts of gypsum,
18~25 parts of golden cypress, 6~11 parts of amylase, 9~14 parts of vegetalitas lactic acid bacteria.
It is preferred that, plant lactobacillus can be Lactobacillus plantarum.
It is preferred that, amylase can be alpha-amylase, beta amylase, carbohydrase and the one of which of isoamylase or its group
Close.
The above-mentioned preparation method for being used to prevent and treat the composition of porcine hyperthermia, its step is as follows:
(1) by radix bupleuri, sweet wormwood, gypsum, golden cypress, amylase and the mixing of vegetalitas lactic acid bacteria are placed in closed fermenter
In;
(2) toward water vapour is passed through in the closed fermenter, reach the relative humidity in the closed fermenter
More than 80%;
(3) be under conditions of 30 DEG C~45 DEG C after aerobic fermentation 40~55 hours in temperature, then carry out anaerobic fermentation 72~
After 85 hours;
(4) composition after the anaerobic fermentation is dried.
Before above-mentioned step (1), in order to fully fermentation, it can also include radix bupleuri, sweet wormwood, gypsum, golden cypress, form sediment
The step of powder enzyme and vegetalitas lactic acid bacteria are crushed respectively.
In above-mentioned step (2), it can be stirred when being passed through water vapour to closed fermenter, so that composition thing
The humidity of matter is uniform.
, can be by the way that closed fermenter be positioned over into the thermostatic chamber that temperature is 30 DEG C~45 DEG C in above-mentioned step (3)
The interior temperature to control closed fermenter, it is of course also possible to meet temperature requirement by other temperature controlled modes.30
DEG C~45 DEG C under conditions of aerobic fermentation after 40~55 hours, composition can be transferred to other environment for being adapted to anaerobic fermentations
Middle carry out anaerobic fermentation, but the loss of material is caused in order to avoid metastatic composition, can be by closed fermenter
Continue anaerobic fermentation under conditions of starvation.
In above-mentioned steps (4), drying operation can be carried out by hot-water heating dryer.Wherein, can be with during aerobic fermentation
By gas valve toward being passed through the oxygen or air by sterilizing in fermentation tank and being stirred, so that oxygen or air can
To be thoroughly mixed among composition, to ensure the abundant complete of aerobic fermentation.It is of course also possible to regulate and control by other means
Oxygen/air content in fermentation tank, to ensure the oxygen/air that abundance can be provided in the aerobic fermentation stage.
Preferably, in order that pig more preferably digests and assimilates the active ingredient in composition and facilitates composition to be mixed with feed
Close, can also comprise the following steps after step (4):Composition powder after drying is broken to 100~300 mesh.
Above-mentioned preparation method, prepares composition, technique is simple and can keep various Chinese herbal medicines by the way of fermentation
Medical value so that composition for preventing and controlling effect is good.
It by said composition and feed is 1 by weight that the application method of the above-mentioned composition for preventing and treating porcine hyperthermia, which is,:
(400~600), which are added in feed, to be used.
Technical scheme and technique effect are described further below by way of specific embodiment.
In embodiment 1~5, preparation method is:First by radix bupleuri, sweet wormwood, gypsum, golden cypress, amylase, vegetalitas lactic acid
Bacterium mixing is placed in closed fermenter, is then passed through water vapour to the closed fermenter, is made in closed fermenter
Relative humidity reach after requirement, aerobic fermentation, then carry out anaerobic fermentation;Finally the composition after anaerobic fermentation is dried
It is dry.Wherein, the component for being used to prevent and treat the composition of porcine hyperthermia in embodiment 1~5 is as shown in table 1, the preparation condition such as institute of table 2
Show:
Table 1
Component | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 |
Radix bupleuri (gram) | 1800 | 2050 | 1300 | 2500 | 3000 |
Sweet wormwood (gram) | 2700 | 2200 | 1500 | 1950 | 1000 |
Gypsum (gram) | 2200 | 3200 | 1200 | 1900 | 2600 |
Golden cypress (gram) | 1800 | 1000 | 2500 | 3000 | 2200 |
Amylase (gram) | 600 | 1100 | 1400 | 1700 | 850 |
Vegetalitas lactic acid bacteria (gram) | 1800 | 1000 | 1400 | 500 | 900 |
Table 2
Preparation condition | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 |
Relative humidity (%) | 80 | 85 | 90 | 95 | 90 |
Aerobic fermentation temperature (DEG C) | 30 | 37 | 40 | 45 | 42 |
The aerobic fermentation time (hour) | 40 | 45 | 42 | 45 | 55 |
The anaerobic fermentation time (hour) | 72 | 76 | 80 | 85 | 80 |
Grinding particle size (mesh) | 100 | 150 | 200 | 250 | 300 |
The vegetalitas lactic acid bacteria of above-described embodiment 1~3 is newborn to provide plant for Cangzhou Zhongxin Biological Technology Co., Ltd.
Bacillus, the Lactobacillus plantarum that the vegetalitas lactic acid bacteria of embodiment 4~5 provides for Shandong sunflower bio tech ltd.On
State the alpha-amylase that amylase used in embodiment 1~3 provides for the taste bio tech ltd of Hebei hundred, embodiment 4~5
The carbohydrase that used amylase provides for Shandong Su Kehan bioengineering limited company.
In order to further illustrate that a kind of composition for being used to prevent and treat porcine hyperthermia that the present invention is provided is prevented porcine hyperthermia
Effect is controlled, clinical observation on the therapeutic effect experiment has been carried out to the composition of the present invention, the present invention is expanded on further below by way of test example
The beneficial effect of composition:
Experiment 1:The toxicological test of the Chinese medicine composition of the present invention:
ICR mouse 60 are selected, male and female half and half, body weight is randomly divided into 6 groups, every group 10, is respectively in (25 ± 5) gram
Blank control group and test group 1~5, blank control group feeding basal feed, feeding with the addition of embodiment 1 to test group 1~5 respectively
The feed of~5 composition, the i.e. feeding of test group 1 with the addition of the feed of the composition of embodiment 1, and the feeding of test group 2 with the addition of
The feed of the composition of embodiment 2, the feeding of test group 3 with the addition of the feed of the composition of embodiment 3, the addition of the feeding of test group 4
The feed of the composition of embodiment 4, the feeding of test group 5 with the addition of the feed of the composition of embodiment 5.Group in each test group
It is 1 to close by the weight ratio of composition and feed:50 are added in feed.Wherein, the forage volume that each group is fed is identical, feeds daily
Food 2 times, after 6 hours.Continuously feed and observe after 15 days, as a result all mouse are strong deposits, its daily routines, hair, body weight,
Food ration, excreta are showed no exception.4 are randomly selected from each group mouse, male and female half and half check that blood and blood biochemical refer to
Mark, takes dissection after blood to carry out pathological examination.
Checked more than, the Index for examination of each group mouse is in normal range (NR), and test group 1~5 and blank control group
Phase less notable difference.Toxicological test proves that the medicine no toxic effects and adverse reaction, clinical practice are safe and reliable.
Experiment 2:
The growing and fattening pigs 350 in certain pig farm are selected, this batch of growing and fattening pigs body temperature occur and are increased to 40 DEG C~42.5 DEG C, adopt
Appetite declines, spiritual depressed, rubefaction, edge cyanosis in one's ear after ear, expiratory dyspnea, the symptom such as constipation, is diagnosed as pig hyperpyrexia
Disease.It is random that this batch of pig is divided into 7 groups, every group 50, and every group of pig isolation is housed in condition identical pigsty and using same
The management mode of sample.Wherein, group 1 is blank control group, is only fed with basal feed;Group 2~groups 7 are test group, and group 2 is to add
The forage feed of composition in embodiment 1, group 3 is with the addition of the forage feed of composition in embodiment 2, and group 4 is to add
Added the forage feed of the composition in embodiment 3, group 5 with the addition of the forage feed of the composition in embodiment 4, group 6 with
It with the addition of the forage feed of the composition in embodiment 5, group 7 is to the addition of the forage feed of antibiotic.Combination in group 2~3
Thing addition is:The weight ratio of composition and feed is 1:400, group 4~6 in composition addition be:Composition and feed
Weight ratio be 1:600, organize the usage and dosage regulation of antibiotic addition to specifications in 7.Give each pig respectively every time
Circle delivers the pig feed of identical weight, and 3 times a day, every time after 4 hours, pig free choice feeding is regularly observed and records pig daily
Situation.After continuous nursing 25 days, each group is fed 5 days using basal feed, experiment is completed totally after 30 days, by the data of gained
Data statistics is carried out, 3 are specifically the results are shown in Table.
Wherein, in this process of the test, the standard of curative effect is:The body temperature of sick pig, body colour, essence after the completion of healing finger to finger test
Refreshing state, feed intake etc. are recovered normally, and are not recurred after drug withdrawal;Body temperature body colour, the spirit of sick pig after the completion of effective finger to finger test
State, feed intake etc. are obviously improved or recover normal;The symptom of sick pig is not obviously improved or dead after the completion of invalid finger to finger test.
Table 3
Sick pig number (head) | Invalid (head) | Effectively (head) | Cure (head) | |
Group 1 | 50 | 50 | 0 | 0 |
Group 2 | 50 | 9 | 41 | 32 |
Group 3 | 50 | 10 | 40 | 30 |
Group 4 | 50 | 5 | 45 | 36 |
Group 5 | 50 | 8 | 42 | 33 |
Group 6 | 50 | 9 | 41 | 31 |
Group 7 | 50 | 28 | 22 | 15 |
By the result of experiment 2, the composition in the embodiment of the present invention can prevent and treat porcine hyperthermia and curative effect is better than
The effect of antibiotic preventing and treating.
Experiment 3:
The sodium selenite 240 that certain pig farm has just been born is selected, and this batch of piglet is raised 1 month under identical condition
This batch of piglet is divided into 6 groups at random afterwards, every group 40, every group of piglet is housed in condition identical pigsty respectively, using phase
Same management mode management.Wherein, group 1 is blank control group, is only fed with basal feed;Group 2 is attacks malicious control group, with basis
After forage feed 1 month, it is not administered after attacking PRRS virus strain, and continues to feed 15 days with basal feed;Group 3~groups 6
For test group, wherein, after forage feed 1 month of the group 3 with the addition of the composition in embodiment 1, attack PRRS virus poison
Change after strain and fed 15 days with basal feed;After forage feed 1 month of the group 4 with the addition of the composition in embodiment 3, pig is attacked blue
Change after otopathy virus stain and fed 15 days with basal feed;Group 5 is to the addition of the forage feed 1 of the composition in embodiment 5
After month, attack to change after PRRS virus strain and fed 15 days with basal feed;Group 6 is to the addition of the forage feed 1 of antibiotic
After month, attack to change after PRRS virus strain and fed 15 days with basal feed.Group 2~5 in composition addition be:Composition
Weight ratio with feed is 1:500, organize the usage and dosage regulation of antibiotic addition to specifications in 6.Give respectively every time
Each pigsty delivers the pig feed of identical weight, 3 times a day, every time after 4 hours, pig free choice feeding, and timing observation daily is simultaneously
Record the situation of pig.The data of gained are subjected to data statistics after off-test, 4 are specifically the results are shown in Table.
Wherein, in this process of the test, after the completion of morbidity finger to finger test, pig appearance spirit is depressed, (body temperature is raised to 40 degree for heating
More than), the symptom such as skin is blue, feed intake declines, expiratory dyspnea;Death refers in process of the test, and pig is dead.
Table 4
Total pig number (only) | Morbidity is (only) | Dead (only) | |
Group 1 | 40 | 0 | 0 |
Group 2 | 40 | 40 | 23 |
Group 3 | 40 | 13 | 0 |
Group 4 | 40 | 10 | 0 |
Group 5 | 40 | 11 | 0 |
Group 6 | 40 | 29 | 0 |
By the result of experiment 3, the composition in the embodiment of the present invention has the effect of preventing swine high fever, and in advance
Anti- effect is better than the effect of antibiotic prophylaxis.And found during experiment, the average daily consumption of feed of group 1 is 25kg,
The average daily consumption of feed of group 2 is 8kg, and the average daily consumption of feed of group 3~groups 5 is 18kg, and the average daily consumption of feed of group 6 is
12kg.As can be seen here, the composition in the embodiment of the present invention is more suitable for the taste of pig compared to antibiotic, can improve the food of pig
It is intended to.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
Any modifications, equivalent substitutions and improvements made within refreshing and principle etc., should be included in the scope of the protection.
Claims (7)
1. a kind of composition for being used to prevent and treat porcine hyperthermia, it is characterised in that by weight, the composition includes:Radix bupleuri 13
~30 parts, 10~27 parts of sweet wormwood, 12~32 parts of gypsum, 10~30 parts of golden cypress, 6~17 parts of amylase, vegetalitas lactic acid bacteria 5~18
Part.
2. the composition as claimed in claim 1 for being used to prevent and treat porcine hyperthermia, it is characterised in that by weight, the combination
Thing includes:13~25 parts of radix bupleuri, 10~22 parts of sweet wormwood, 12~26 parts of gypsum, 10~25 parts of golden cypress, 6~13 parts of amylase, plant
5~14 parts of lactic acid bacteria of property.
3. the composition as claimed in claim 1 for being used to prevent and treat porcine hyperthermia, it is characterised in that by weight, the combination
Thing includes:18~25 parts of radix bupleuri, 15~22 parts of sweet wormwood, 22~26 parts of gypsum, 18~25 parts of golden cypress, 6~11 parts of amylase, plant
9~14 parts of lactic acid bacteria of property.
4. a kind of method for being used to prevent and treat the composition of porcine hyperthermia prepared as described in any one of 1~3 claim, its feature
It is, the described method comprises the following steps:
By radix bupleuri, sweet wormwood, gypsum, golden cypress, amylase and the mixing of vegetalitas lactic acid bacteria are placed in closed fermenter;
Be passed through water vapour in toward the closed fermenter, make the relative humidity in the closed fermenter reach 80% with
On;
After aerobic fermentation under conditions of temperature is 30 DEG C~45 DEG C 40~55 hours, then carry out anaerobic fermentation 72~85 hours
Afterwards;
Composition after the anaerobic fermentation is dried.
5. preparation method as claimed in claim 4, it is characterised in that described by radix bupleuri, sweet wormwood, gypsum, golden cypress, amylase and
The step that the mixing of vegetalitas lactic acid bacteria is placed in closed fermenter also includes:
By radix bupleuri, sweet wormwood, gypsum, golden cypress, amylase and vegetalitas lactic acid bacteria are crushed respectively.
6. preparation method as claimed in claim 4, it is characterised in that the composition by after the anaerobic fermentation is dried
Also include after dry step:
The composition powder is broken into 100~300 mesh.
7. a kind of being used for as described in any one of 1~3 claim prevents and treats the application method of the composition of porcine hyperthermia, its feature
It is, is 1 by weight by the composition and feed:(400~600), which are added in feed, to be used.
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CN108578590A (en) * | 2018-05-28 | 2018-09-28 | 泗县根叶鸿养殖有限公司 | It is a kind of to treat high fever syndrome of pigs bacterium solution and its preparation method and application |
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