CN107233393A - A kind of pharmaceutical composition for treating gout - Google Patents

A kind of pharmaceutical composition for treating gout Download PDF

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Publication number
CN107233393A
CN107233393A CN201710301253.6A CN201710301253A CN107233393A CN 107233393 A CN107233393 A CN 107233393A CN 201710301253 A CN201710301253 A CN 201710301253A CN 107233393 A CN107233393 A CN 107233393A
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China
Prior art keywords
parts
pharmaceutical composition
gout
root
chinese medicine
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CN201710301253.6A
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Chinese (zh)
Inventor
蔡哲宇
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Guangzhou Wisdom Biotechnology Co Ltd
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Guangzhou Wisdom Biotechnology Co Ltd
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Priority to CN201710301253.6A priority Critical patent/CN107233393A/en
Publication of CN107233393A publication Critical patent/CN107233393A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486Millettia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/68Plantaginaceae (Plantain Family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of pharmaceutical composition for treating gout, the Chinese medicine matched by following parts by weight is constituted:10 ~ 30 parts of radix semiaquilegiae, 15 ~ 25 parts of Sargent gloryvine, 20 ~ 40 parts of Canton love-pea vine, 20 ~ 30 parts of the root of bidentate achyranthes, 20 ~ 40 parts of plantain seed.Present invention treatment gout effect is good, and clinical test is proved, with obvious therapeutic effect.

Description

A kind of pharmaceutical composition for treating gout
Technical field
The present invention relates to pharmaceutical composition, and in particular to a kind of pharmaceutical composition for treating gout.
Background technology
Gout is by monosodium urate salt(MSU)Deposition caused by crystal correlation arthropathy, with purine metabolic disturbance and (Or)Hyperuricemia caused by underexcretion is directly related, refers in particular to acute characteristic arthritis and chronic gout stone disease Disease, mainly includes acute attack arthritis, tophus formation, tophaceous chornic arthritis, urate nephropathy and uric acid Lithangiuria, severe one may occur in which joint deformity and renal insufficiency.
In recent years, number of patients substantially increased.At present to this sick treatment still based on Western medicine, conventional has colchicum Alkali, allopurinol, foregoing medicine, mostly abirritant, it is difficult to effect a radical cure, and all with obvious toxic side effect, such as stomach and intestine not Hemorrhagic enteritis can occur for suitable, severe patient, and blood middle leukocytes are reduced, severe patient can cause aplastic anemia, alopecia, flesh Disease, hepatic disorder, depression etc..Before this, there are 25-component sophora flower ball, vast stretch of wooded country chinkuning for treating the Chinese medicine of gout Etc. a small amount of patent medicine, but cure rate is not also high, and part sufferer curative effect is not obvious.
The content of the invention
To overcome existing technological deficiency, the invention provides a kind of medicine of the treatment gout good for goat curative effect Composition.
To realize the purpose of the present invention, it is achieved using following technical scheme:
A kind of pharmaceutical composition for treating gout, the Chinese medicine matched by following parts by weight is constituted:10 ~ 30 parts of radix semiaquilegiae is red 15 ~ 25 parts of rattan, 20 ~ 40 parts of Canton love-pea vine, 20 ~ 30 parts of the root of bidentate achyranthes, 20 ~ 40 parts of plantain seed.
Radix semiaquilegiae is sweet, hardship, cold in nature, Return liver, stomach, with clearing heat and detoxicating, the effect of dispersing swelling and dissipating binds.Sargent gloryvine is Lardizabalaceae The rattan of plant sargentodoxa cuneata, bitter is mild-natured, returns large intestine, Liver Channel, has removing toxicity for eliminating carbuncles, promoting blood circulation and stopping pain, dispelling wind and eliminating dampness, disinsection efficiency. Canton love-pea vine is sweet, slight bitter, cool, there is removing dampness through diuresis and removing jaundice, clearing heat and detoxicating, the effect of dispersing the depressed liver-qi and alleviating pain.Root of bidentate achyranthes bitter, sweet, acid, put down, Return liver, Kidney channel, with dispelling stasis of blood and stimulating the menstrual flow, filling liver kidney, strengthening the bones and muscles, inducing diuresis for treating strangurtia, the effect ensuringd proper downward flow of the blood.Plantain seed is sweet in flavor and cold in property, enter kidney, Bladder, liver, lung channel, function promoting diuresis for stranguria, excreting dampness antidiarrheal, clear liver and improve vision, clearing heat and eliminating phlegm.Pharmaceutical formulation of the present invention is scientific and reasonable, Acted synergistically between each component, can promoting blood circulation and removing obstruction in channels, regulating qi-flowing for relieving pain, righting method heresy, regulation internal system, to gout with preferable Therapeutic effect.
Further, the Chinese medicine that aforementioned pharmaceutical compositions are matched by following parts by weight is constituted:15 ~ 25 parts of radix semiaquilegiae, 18 ~ 22 parts of Sargent gloryvine, 25 ~ 30 parts of Canton love-pea vine, 22 ~ 28 parts of the root of bidentate achyranthes, 25 ~ 35 parts of plantain seed.
Further, the Chinese medicine that aforementioned pharmaceutical compositions are matched by following parts by weight is constituted:20 parts of radix semiaquilegiae, Sargent gloryvine 20 parts, 26 parts of Canton love-pea vine, 24 parts of the root of bidentate achyranthes, 30 parts of plantain seed.
Compared with the prior art, present invention treatment gout effect is good, and clinical test is proved, with obvious therapeutic effect.
Embodiment
To make the object, technical solutions and advantages of the present invention clearer, further is made to embodiment of the present invention below Explain.
Embodiment 1
A kind of pharmaceutical composition for treating gout, the Chinese medicine matched by following parts by weight is constituted:10 parts of radix semiaquilegiae, Sargent gloryvine 15 Part, 20 parts of Canton love-pea vine, 20 parts of the root of bidentate achyranthes, 20 parts of plantain seed.
Each group in this formula is divided into 1 dose of dose, to be decocted in water for oral dose, daily 1 dose, is taken for 2 times per natural gift.
Embodiment 2
A kind of pharmaceutical composition for treating gout, the Chinese medicine matched by following parts by weight is constituted:30 parts of radix semiaquilegiae, Sargent gloryvine 25 Part, 40 parts of Canton love-pea vine, 30 parts of the root of bidentate achyranthes, 40 parts of plantain seed.
Each group in this formula is divided into 1 dose of dose, to be decocted in water for oral dose, daily 1 dose, is taken for 2 times per natural gift.
Embodiment 3
A kind of pharmaceutical composition for treating gout, the Chinese medicine matched by following parts by weight is constituted:20 parts of radix semiaquilegiae, Sargent gloryvine 20 Part, 26 parts of Canton love-pea vine, 24 parts of the root of bidentate achyranthes, 30 parts of plantain seed.
Each group in this formula is divided into 1 dose of dose, to be decocted in water for oral dose, daily 1 dose, is taken for 2 times per natural gift.
Embodiment 4
Summarized using the clinical efficacy of embodiment 1:
First, clinical data:100 patient with gout of clinical treatment, patient checks through joint x ray photograph, blood uric acid, urine uric acid etc. Make a definite diagnosis.
2nd, treatment method:Each group in this formula is divided into 1 dose of dose, to be decocted in water for oral dose, daily 1 dose, per 2 clothes of natural gift With, continuously take one month observation curative effect.
3rd, therapeutic evaluation:
Cure:Symptom disappears, laboratory examination is normal.
Take a turn for the better:Arthroncus is disappeared, and pain relief, laboratory examination makes moderate progress.
It is invalid:Symptom and laboratory examination are unchanged.
4th, therapeutic effect:Using present invention treatment 100,74 are as a result cured, is taken a turn for the better 20, invalid 6.
5th, model case
1. case 1, Mr. Wang, man, 45 years old, toe, ankle-joint, knee joint were red and swollen, heat pain, knee articulation inconvenience, blood urine 432 μm of ol/L of acid, are diagnosed as goat.After drug therapy made from embodiment 1 one month, symptom mitigation is controlled after two months More, follow-up 2 years is without recurrence.
2. case 2, Zhang, female, 52 years old, wrist joint, elbow joint were red and swollen, heat pain, exercising elbow joint inconvenience, blood uric acid 245 μm of ol/L, are diagnosed as goat.After drug therapy made from embodiment 1 one month, symptom mitigation is controlled after two months More, freely, follow-up 2 years is without recurrence for wrist joint and exercising elbow joint.
3. case 3, Zhang, man, 61 years old, the swelling of left foot toe, stiff, pain, 371 μm of ol/L of blood uric acid were diagnosed as Goat.After drug therapy made from embodiment 1 one month, symptom mitigation is cured after two months, wrist joint and elbow joint Freely, follow-up 2 years is without recurrence for activity.
Embodiment 5
Summarized using the clinical efficacy of embodiment 2:Patient on medication's formula is the formula of embodiment 2, and other are constant.
Therapeutic effect:Using present invention treatment 100,76 are as a result cured, is taken a turn for the better 19, invalid 5.
Embodiment 6
Summarized using the clinical efficacy of embodiment 3:Patient on medication's formula is the formula of embodiment 3, and other are constant.
Therapeutic effect:Using present invention treatment 100,80 are as a result cured, is taken a turn for the better 17, invalid 3.

Claims (3)

1. a kind of pharmaceutical composition for treating gout, it is characterised in that the Chinese medicine matched by following parts by weight is constituted:Semiaquilegia adoxoides 10 ~ 30 parts of son, 15 ~ 25 parts of Sargent gloryvine, 20 ~ 40 parts of Canton love-pea vine, 20 ~ 30 parts of the root of bidentate achyranthes, 20 ~ 40 parts of plantain seed.
2. the pharmaceutical composition for the treatment of gout according to claim 1, it is characterised in that matched by following parts by weight Chinese medicine is constituted:15 ~ 25 parts of radix semiaquilegiae, 18 ~ 22 parts of Sargent gloryvine, 25 ~ 30 parts of Canton love-pea vine, 22 ~ 28 parts of the root of bidentate achyranthes, 25 ~ 35 parts of plantain seed.
3. the pharmaceutical composition for the treatment of gout according to claim 2, it is characterised in that matched by following parts by weight Chinese medicine is constituted:20 parts of radix semiaquilegiae, 20 parts of Sargent gloryvine, 26 parts of Canton love-pea vine, 24 parts of the root of bidentate achyranthes, 30 parts of plantain seed.
CN201710301253.6A 2017-05-02 2017-05-02 A kind of pharmaceutical composition for treating gout Withdrawn CN107233393A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710301253.6A CN107233393A (en) 2017-05-02 2017-05-02 A kind of pharmaceutical composition for treating gout

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710301253.6A CN107233393A (en) 2017-05-02 2017-05-02 A kind of pharmaceutical composition for treating gout

Publications (1)

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CN107233393A true CN107233393A (en) 2017-10-10

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CN201710301253.6A Withdrawn CN107233393A (en) 2017-05-02 2017-05-02 A kind of pharmaceutical composition for treating gout

Country Status (1)

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CN (1) CN107233393A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107929601A (en) * 2017-12-25 2018-04-20 广西壮要方医院有限公司 A kind of medicine for treating gout

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107929601A (en) * 2017-12-25 2018-04-20 广西壮要方医院有限公司 A kind of medicine for treating gout

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Application publication date: 20171010