CN107233379A - It is a kind of to treat Chinese medicine preparation of rheumatic arthritis and preparation method thereof - Google Patents
It is a kind of to treat Chinese medicine preparation of rheumatic arthritis and preparation method thereof Download PDFInfo
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- CN107233379A CN107233379A CN201710502381.7A CN201710502381A CN107233379A CN 107233379 A CN107233379 A CN 107233379A CN 201710502381 A CN201710502381 A CN 201710502381A CN 107233379 A CN107233379 A CN 107233379A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The invention discloses a kind of Chinese medicine preparation for treating rheumatic arthritis and preparation method thereof, wherein the Chinese medicine preparation is made up of the Chinese medicine of following parts by weight：25 ~ 35 parts of sargentodoxa cuneata, 15 ~ 25 parts of the bark of eucommia, 10 ~ 20 parts of bush, 25 ~ 30 parts of Canton love-pea vine.It is provided by the present invention treatment rheumatic arthritis Chinese medicine preparation have scientific formula, rationally, determined curative effect is convenient to take, treat rheumatic arthritis determined curative effect advantage, can effectively treat rheumatic arthritis, alleviate rheumatic arthritis symptom.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for treating rheumatic arthritis and preparation method thereof.
Background technology
Rheumatic arthritis is a kind of one of common joint diseases of clinic, and it is the autoimmunity based on arthropathy
Property disease.From 1930s recognizes this disease, the whole world has millions of patients to go to a doctor every year.Provided according to current statistics
Material display, the incidence of disease of the rheumatic arthritis in crowd is up to 9%, also in the trend risen year by year.The whole nation now there are about more than 100,000,000
People suffers from rheumatic arthritis, the person between twenty and fifty of sick multiple 20-45 Sui.Abstract investigation in 2001, more than 35 years old person in middle and old age's incidence of disease
For 17%, this is originally the susceptible disease of person in middle and old age, but with the continuous improvement of material conditions, air-conditioning enters more families, made
More people have suffered from the disease of arthralgia, that is, " air conditioner disease " said now, no matter and age, children and adolescents
Patient is also more and more.When wherein thering are many people to start morbidity unconsciously, asymptomatic, but with advancing age, arthritis
The symptom of pain is more and more severe.
The content of the invention
To overcome existing technological deficiency, rheumatic arthritis Chinese medicine system evident in efficacy is treated the invention provides a kind of
Agent and preparation method thereof.
To realize the purpose of the present invention, it is achieved using following technical scheme：
A kind of Chinese medicine preparation for treating rheumatic arthritis, is made up of the Chinese medicine of following parts by weight：25 ~ 35 parts of sargentodoxa cuneata, Du
Secondary 15 ~ 25 parts, 10 ~ 20 parts of bush, 25 ~ 30 parts of Canton love-pea vine.
Sargentodoxa cuneata is mild-natured in the present invention, bitter, returns large intestine channel, Liver Channel, the work(with clearing heat and detoxicating, promoting blood circulation by removing wind, analgesic
Effect, belongs to blood-activating analgesic.The bark of eucommia is warm-natured, sweet, return liver warp, kidney channel, with filling liver kidney, controls spinal column ache, foot and knee flaccidity, urine
The heeltap, hypertension, antiabortive effect.Bush is mild-natured, sweet, salty, thoughts of returning home warp, Liver Channel, the spleen channel, and with promoting circulation of blood dissolving stasis, detumescence stops
Effect of pain.Canton love-pea vine is sweet, slight bitter, cool in nature, Return liver, stomach, has effects that removing dampness through diuresis and removing jaundice, clearing heat and detoxicating, dispersing the depressed liver-qi and alleviating pain.
Above-mentioned Chinese medicine is simultaneously dehumidified with common tool removing toxic substances, and clearing heat and cooling blood is easing joint movement, strengthening the bones and muscles, goes the effects such as wind dehumidifying；Thus to rheumatism
Property arthritis or rheumatoid arthritis have therapeutic effect.
Further, above-mentioned Chinese medicine preparation is made up of the Chinese medicine of following parts by weight：33 parts of sargentodoxa cuneata, 22 parts of the bark of eucommia, Soviet Union
15 parts of wood, 27 parts of Canton love-pea vine.
The preparation method of above-mentioned Chinese medicine preparation comprises the following steps：
S1：Sargentodoxa cuneata, the bark of eucommia, bush and Canton love-pea vine are taken by bulk drug proportioning, the decocting that quality is 5 ~ 10 times of material quality is added
Boil 2 ~ 3 hours, secondary, decocting liquid filtering is decocted altogether, secondary filtrate is merged, heating is concentrated into solution density for 2 g/ml, adds
Ethanol, makes ethanol mass fraction up to 80%, stands 12 ~ 16 hours, and filtering reclaims ethanol, obtains water decoction-alcohol sedimentation thing；Alcohol hypostasis is true
Sky is dried and crushed into medicinal extract fine powder；
S2：Medicinal extract fine powder, maltodextrin or starch are mixed by weight 5: 1~2 ratio, are conventionally made various
Formulation.
Wherein, the various formulations include granule, capsule, tablet.
The Chinese medicine preparation for the treatment of rheumatic arthritis provided by the present invention has scientific formula, reasonable, determined curative effect, clothes
With convenient, the advantage of rheumatic arthritis determined curative effect is treated, rheumatic arthritis can be effectively treated, alleviate rheumatic arthritis
Symptom.The all pure Chinese medicines of this composition component, no obvious adverse reaction, safe, patient compliance is preferable.
Embodiment
To make the object, technical solutions and advantages of the present invention clearer, further is made to embodiment of the present invention below
Explain.
Embodiment 1
A kind of Chinese medicine preparation for treating rheumatic arthritis, is made up of the Chinese medicine of following parts by weight：33 parts of sargentodoxa cuneata, the bark of eucommia 22
Part, 15 parts of bush, 27 parts of Canton love-pea vine.
The preparation method of above-mentioned Chinese medicine preparation comprises the following steps：
S1：Sargentodoxa cuneata, the bark of eucommia, bush and Canton love-pea vine are taken by above-mentioned raw materials medicine proportioning, the decocting that quality is 6 times of material quality is added
Boil 2.5 hours, secondary, decocting liquid filtering is decocted altogether, secondary filtrate is merged, heating is concentrated into solution density for 2 g/ml, adds
Ethanol, makes ethanol mass fraction up to 80%, stands 15 hours, and filtering reclaims ethanol, obtains water decoction-alcohol sedimentation thing；Alcohol hypostasis vacuum is done
It is dry to be ground into medicinal extract fine powder；
S2：Medicinal extract fine powder, maltodextrin or starch are mixed by weight 10: 3 ratio, instant is conventionally made
The g of granula pastille 4.
Usage：One bag of granulated quickly dissolving is poured into cup, 150 ml hot water is added and directly reconstitutes, on behalf of the tea.Daily 2 ~ 3
It is secondary.
Clinical observation：Treating rheumatic arthritis 150 is tried, 126 will be taken medicine in afternoon to 3 days, and 11 in after medication 5
My god, arthralgia mitigates, and arthroncus starts to disappear, and then joint function starts to recover, and erythema nodosa disappears, and body temperature gradually drops.
After being treated through 2 ~ 5 weeks, 124 healings, 16 significantly improve.
Embodiment 2
A kind of Chinese medicine preparation for treating rheumatic arthritis, is made up of the Chinese medicine of following parts by weight：25 parts of sargentodoxa cuneata, the bark of eucommia 15
Part, 10 parts of bush, 25 parts of Canton love-pea vine.
The preparation method of above-mentioned Chinese medicine preparation comprises the following steps：
S1：Sargentodoxa cuneata, the bark of eucommia, bush and Canton love-pea vine are taken by bulk drug proportioning, quality is added and boils 2 for the decocting of 5 times of material quality
Hour, secondary, decocting liquid filtering is decocted altogether, secondary filtrate is merged, and heating is concentrated into solution density for 2 g/ml, adds ethanol,
Make ethanol mass fraction up to 80%, stand 12 hours, filtering reclaims ethanol, obtains water decoction-alcohol sedimentation thing；Alcohol hypostasis is dried in vacuo powder
It is broken into medicinal extract fine powder；
S2：Medicinal extract fine powder, maltodextrin or starch are mixed by weight 5: 1 ratio, capsule is conventionally made,
Every 0.8 g.
Usage：5 every time, daily 2 ~ 3 times.
Clinical observation：Treating rheumatic arthritis 150 is tried, 124 will be taken medicine in afternoon to 3 days, and 15 in after medication 5
My god, arthralgia mitigates, and arthroncus starts to disappear, and then joint function starts to recover, and erythema nodosa disappears, and body temperature gradually drops.
After being treated through 2 ~ 5 weeks, 120 healings, 18 significantly improve.
Embodiment 3
A kind of Chinese medicine preparation for treating rheumatic arthritis, is made up of the Chinese medicine of following parts by weight：35 parts of sargentodoxa cuneata, the bark of eucommia 25
Part, 20 parts of bush, 30 parts of Canton love-pea vine.
The preparation method of above-mentioned Chinese medicine preparation comprises the following steps：
S1：Sargentodoxa cuneata, the bark of eucommia, bush and Canton love-pea vine are taken by bulk drug proportioning, quality is added and boils 3 for the decocting of 10 times of material quality
Hour, secondary, decocting liquid filtering is decocted altogether, secondary filtrate is merged, and heating is concentrated into solution density for 2 g/ml, adds ethanol,
Make ethanol mass fraction up to 80%, stand 16 hours, filtering reclaims ethanol, obtains water decoction-alcohol sedimentation thing；Alcohol hypostasis is dried in vacuo powder
It is broken into medicinal extract fine powder；
S2：Medicinal extract fine powder, maltodextrin or starch are mixed by weight 5: 2 ratio, tablet is conventionally made, often
Piece weighs 0.8 g.
Usage：5 tablets once, daily 2 ~ 3 times.
Clinical observation：Treating rheumatic arthritis 150 is tried, 118 will be taken medicine in afternoon to 3 days, and 18 in after medication 5
My god, arthralgia mitigates, and arthroncus starts to disappear, and then joint function starts to recover, and erythema nodosa disappears, and body temperature gradually drops.
After being treated through 2 ~ 5 weeks, 116 healings, 21 significantly improve.
Claims (4)
1. a kind of Chinese medicine preparation for treating rheumatic arthritis, it is characterised in that be made up of the Chinese medicine of following parts by weight：Big blood
25 ~ 35 parts of rattan, 15 ~ 25 parts of the bark of eucommia, 10 ~ 20 parts of bush, 25 ~ 30 parts of Canton love-pea vine.
2. the Chinese medicine preparation for the treatment of rheumatic arthritis according to claim 1, it is characterised in that by following parts by weight
Chinese medicine be made：33 parts of sargentodoxa cuneata, 22 parts of the bark of eucommia, 15 parts of bush, 27 parts of Canton love-pea vine.
3. the preparation method of Chinese medicine preparation according to claim 1 or 2, it is characterised in that comprise the following steps：
S1：Sargentodoxa cuneata, the bark of eucommia, bush and Canton love-pea vine are taken by bulk drug proportioning, the decocting that quality is 5 ~ 10 times of material quality is added
Boil 2 ~ 3 hours, secondary, decocting liquid filtering is decocted altogether, secondary filtrate is merged, heating is concentrated into solution density for 2 g/ml, adds
Ethanol, makes ethanol mass fraction up to 80%, stands 12 ~ 16 hours, and filtering reclaims ethanol, obtains water decoction-alcohol sedimentation thing；Alcohol hypostasis is true
Sky is dried and crushed into medicinal extract fine powder；
S2：Medicinal extract fine powder, maltodextrin or starch are mixed by weight 5: 1~2 ratio, are conventionally made various
Formulation.
4. the preparation method of Chinese medicine preparation according to claim 3, it is characterised in that the various formulations be granule or
Capsule or tablet.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710502381.7A CN107233379A (en) | 2017-06-27 | 2017-06-27 | It is a kind of to treat Chinese medicine preparation of rheumatic arthritis and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710502381.7A CN107233379A (en) | 2017-06-27 | 2017-06-27 | It is a kind of to treat Chinese medicine preparation of rheumatic arthritis and preparation method thereof |
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| CN107233379A true CN107233379A (en) | 2017-10-10 |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20020066242A (en) * | 2001-02-09 | 2002-08-14 | 이수찬 | A herb medicine for treating an arthritis |
| CN101926926A (en) * | 2010-09-17 | 2010-12-29 | 湖南湘泉制药有限公司 | Traditional Chinese medicinal preparation for treating rheumatic arthritis and chronic infectious arthritis |
| CN104257908A (en) * | 2014-10-04 | 2015-01-07 | 孙玉杰 | Traditional Chinese medicine preparation for treating rheumatic arthritis and preparation method, |
-
2017
- 2017-06-27 CN CN201710502381.7A patent/CN107233379A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20020066242A (en) * | 2001-02-09 | 2002-08-14 | 이수찬 | A herb medicine for treating an arthritis |
| CN101926926A (en) * | 2010-09-17 | 2010-12-29 | 湖南湘泉制药有限公司 | Traditional Chinese medicinal preparation for treating rheumatic arthritis and chronic infectious arthritis |
| CN104257908A (en) * | 2014-10-04 | 2015-01-07 | 孙玉杰 | Traditional Chinese medicine preparation for treating rheumatic arthritis and preparation method, |
Non-Patent Citations (2)
| Title |
|---|
| 程云柱: "风湿类风湿关节炎的中医综合治疗", 《中国民间疗法》 * |
| 陈志鹏等: "《袖珍中草药彩色图谱》", 31 October 2016, 湖南科学技术出版社 * |
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Application publication date: 20171010 |