CN107223249B - 用于实验设计和分析的方法和系统 - Google Patents

用于实验设计和分析的方法和系统 Download PDF

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Publication number
CN107223249B
CN107223249B CN201680009017.0A CN201680009017A CN107223249B CN 107223249 B CN107223249 B CN 107223249B CN 201680009017 A CN201680009017 A CN 201680009017A CN 107223249 B CN107223249 B CN 107223249B
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amplification
amplification curves
list
curves
view
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CN107223249A (zh
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S·里克斯
L·S·刘
K·S·泰欧
Z·W·楚
L·S·卢
V·冯
M·乌伊
D·浩德
S·齐默尔曼
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Life Technologies Corp
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Life Technologies Corp
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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B45/00—ICT specially adapted for bioinformatics-related data visualisation, e.g. displaying of maps or networks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T11/00—Two-dimensional [2D] image generation
    • G06T11/20—Drawing from basic elements
    • G06T11/26—Drawing of charts or graphs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F3/00—Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
    • G06F3/01—Input arrangements or combined input and output arrangements for interaction between user and computer
    • G06F3/048—Interaction techniques based on graphical user interfaces [GUI]
    • G06F3/0481—Interaction techniques based on graphical user interfaces [GUI] based on specific properties of the displayed interaction object or a metaphor-based environment, e.g. interaction with desktop elements like windows or icons, or assisted by a cursor's changing behaviour or appearance
    • G06F3/0482—Interaction with lists of selectable items, e.g. menus
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F3/00—Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
    • G06F3/01—Input arrangements or combined input and output arrangements for interaction between user and computer
    • G06F3/048—Interaction techniques based on graphical user interfaces [GUI]
    • G06F3/0484—Interaction techniques based on graphical user interfaces [GUI] for the control of specific functions or operations, e.g. selecting or manipulating an object, an image or a displayed text element, setting a parameter value or selecting a range
    • G06F3/04842—Selection of displayed objects or displayed text elements
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F3/00—Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
    • G06F3/01—Input arrangements or combined input and output arrangements for interaction between user and computer
    • G06F3/048—Interaction techniques based on graphical user interfaces [GUI]
    • G06F3/0484—Interaction techniques based on graphical user interfaces [GUI] for the control of specific functions or operations, e.g. selecting or manipulating an object, an image or a displayed text element, setting a parameter value or selecting a range
    • G06F3/0485—Scrolling or panning
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F3/00—Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
    • G06F3/01—Input arrangements or combined input and output arrangements for interaction between user and computer
    • G06F3/048—Interaction techniques based on graphical user interfaces [GUI]
    • G06F3/0487—Interaction techniques based on graphical user interfaces [GUI] using specific features provided by the input device, e.g. functions controlled by the rotation of a mouse with dual sensing arrangements, or of the nature of the input device, e.g. tap gestures based on pressure sensed by a digitiser
    • G06F3/0488—Interaction techniques based on graphical user interfaces [GUI] using specific features provided by the input device, e.g. functions controlled by the rotation of a mouse with dual sensing arrangements, or of the nature of the input device, e.g. tap gestures based on pressure sensed by a digitiser using a touch-screen or digitiser, e.g. input of commands through traced gestures
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T3/00—Geometric image transformations in the plane of the image
    • G06T3/40—Scaling of whole images or parts thereof, e.g. expanding or contracting
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging

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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Human Computer Interaction (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Data Mining & Analysis (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • User Interface Of Digital Computer (AREA)
CN201680009017.0A 2015-02-06 2016-02-05 用于实验设计和分析的方法和系统 Active CN107223249B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562113006P 2015-02-06 2015-02-06
US62/113,006 2015-02-06
PCT/US2016/016827 WO2016127086A1 (en) 2015-02-06 2016-02-05 Methods and systems for experiment design and analysis

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CN107223249A CN107223249A (zh) 2017-09-29
CN107223249B true CN107223249B (zh) 2021-06-18

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US (1) US10102653B2 (enExample)
EP (1) EP3254086B1 (enExample)
JP (1) JP6496417B2 (enExample)
KR (1) KR102541746B1 (enExample)
CN (1) CN107223249B (enExample)
BR (1) BR112017016932B1 (enExample)
RU (1) RU2719346C2 (enExample)
SG (2) SG10202006588UA (enExample)
WO (1) WO2016127086A1 (enExample)

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Publication number Priority date Publication date Assignee Title
EP3746225B1 (en) * 2018-01-29 2024-10-30 Gen-Probe Incorporated Analytical systems and methods
USD872109S1 (en) 2018-08-07 2020-01-07 Caterpillar Inc. Display screen or portion thereof with graphical user interface
USD1089275S1 (en) 2021-11-03 2025-08-19 Caterpillar Inc. Display screen or portion thereof with graphical user interface

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WO2003029924A2 (en) * 2001-10-02 2003-04-10 Stratagene Adaptive baseline algorithm for quantitative pcr
US20110025717A1 (en) * 2009-07-31 2011-02-03 Oracle International Corporation Graphical interface with data presence indicators
US20120231458A1 (en) * 2011-03-09 2012-09-13 Samsung Techwin Co., Ltd. Method of acquiring standard curve in real-time pcr
CN104093853A (zh) * 2011-09-30 2014-10-08 生命技术公司 用于可视化和评估数据的方法和系统

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WO2001007896A1 (en) * 1999-07-21 2001-02-01 Tropix, Inc. Luminescence detection workstation
EP1404878A4 (en) * 2001-07-11 2006-12-06 Applera Corp INTERNAL CALIBRATION STANDARDS FOR ELECTROPHORETIC ANALYZES
US7315376B2 (en) * 2005-01-07 2008-01-01 Advanced Molecular Systems, Llc Fluorescence detection system
US7630849B2 (en) * 2005-09-01 2009-12-08 Applied Biosystems, Llc Method of automated calibration and diagnosis of laboratory instruments
US8473216B2 (en) * 2006-11-30 2013-06-25 Fluidigm Corporation Method and program for performing baseline correction of amplification curves in a PCR experiment
BRPI1006682B1 (pt) * 2009-04-16 2020-04-22 Koninl Philips Electronics Nv método para a quantificação relativa de no mínimo um ácido nucleico alvo em uma amostra, método para a quantificação absoluta de no mínimo um ácido nucleico alvo em uma amostra, meios legíveis por máquina e equipamento para a análise das amostras de ácido nucleico
SG184483A1 (en) * 2010-04-08 2012-11-29 Life Technologies Corp Systems and methods for genotyping by angle configuration search
US8572506B2 (en) * 2010-04-09 2013-10-29 Life Technologies Corporation Visualization tool for qPCR genotyping data
JP5848750B2 (ja) * 2010-04-11 2016-01-27 ライフ テクノロジーズ コーポレーション モデルベースのｑＰＣＲのためのシステムおよび方法
WO2012024500A1 (en) * 2010-08-18 2012-02-23 Life Technologies Corporation Chemical coating of microwell for electrochemical detection device
JP5684921B2 (ja) * 2010-12-15 2015-03-18 アクゾ ノーベル ケミカルズ インターナショナル ベスローテン フエンノートシャップＡｋｚｏ Ｎｏｂｅｌ Ｃｈｅｍｉｃａｌｓ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｂ．Ｖ． 紙に塗布するための水性のデンプン含有ポリマー分散液
WO2012106481A1 (en) * 2011-02-01 2012-08-09 Life Technologies Coporation Systems and methods for the analysis of protein melt curve data
WO2013049702A2 (en) * 2011-09-30 2013-04-04 Life Technologies Corporation Systems and methods for biological analysis

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WO2003029924A2 (en) * 2001-10-02 2003-04-10 Stratagene Adaptive baseline algorithm for quantitative pcr
US20110025717A1 (en) * 2009-07-31 2011-02-03 Oracle International Corporation Graphical interface with data presence indicators
US20120231458A1 (en) * 2011-03-09 2012-09-13 Samsung Techwin Co., Ltd. Method of acquiring standard curve in real-time pcr
CN104093853A (zh) * 2011-09-30 2014-10-08 生命技术公司 用于可视化和评估数据的方法和系统

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Publication number Publication date
JP2018506974A (ja) 2018-03-15
SG11201706356XA (en) 2017-09-28
KR102541746B1 (ko) 2023-06-09
RU2719346C2 (ru) 2020-04-17
RU2017131044A (ru) 2019-03-06
RU2017131044A3 (enExample) 2019-07-17
BR112017016932A2 (en) 2018-04-03
US20160239990A1 (en) 2016-08-18
KR20170135832A (ko) 2017-12-08
EP3254086A1 (en) 2017-12-13
JP6496417B2 (ja) 2019-04-03
CN107223249A (zh) 2017-09-29
SG10202006588UA (en) 2020-08-28
US10102653B2 (en) 2018-10-16
EP3254086B1 (en) 2020-08-05
WO2016127086A1 (en) 2016-08-11
BR112017016932B1 (pt) 2021-04-20

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