CN107217051A - 识别热量限制标记物和热量限制模拟物 - Google Patents

识别热量限制标记物和热量限制模拟物 Download PDF

Info

Publication number
CN107217051A
CN107217051A CN201710383186.7A CN201710383186A CN107217051A CN 107217051 A CN107217051 A CN 107217051A CN 201710383186 A CN201710383186 A CN 201710383186A CN 107217051 A CN107217051 A CN 107217051A
Authority
CN
China
Prior art keywords
tissue
genes
gene
expression
amplification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710383186.7A
Other languages
English (en)
Chinese (zh)
Inventor
A·玛斯塔咯迪斯
S·伍德
T·A·波拉
J·L·巴杰
R·温德鲁奇
J·昌
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NSE Products Inc
Original Assignee
NSE Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NSE Products Inc filed Critical NSE Products Inc
Publication of CN107217051A publication Critical patent/CN107217051A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
CN201710383186.7A 2011-06-15 2012-06-15 识别热量限制标记物和热量限制模拟物 Pending CN107217051A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161497476P 2011-06-15 2011-06-15
US61/497,476 2011-06-15
CN201280039802.2A CN103732745A (zh) 2011-06-15 2012-06-15 识别热量限制标记物和热量限制模拟物

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201280039802.2A Division CN103732745A (zh) 2011-06-15 2012-06-15 识别热量限制标记物和热量限制模拟物

Publications (1)

Publication Number Publication Date
CN107217051A true CN107217051A (zh) 2017-09-29

Family

ID=47357787

Family Applications (4)

Application Number Title Priority Date Filing Date
CN201710383186.7A Pending CN107217051A (zh) 2011-06-15 2012-06-15 识别热量限制标记物和热量限制模拟物
CN202511512713.0A Pending CN121271860A (zh) 2011-06-15 2012-06-15 识别热量限制标记物和热量限制模拟物
CN201280039802.2A Pending CN103732745A (zh) 2011-06-15 2012-06-15 识别热量限制标记物和热量限制模拟物
CN202110890757.2A Pending CN113801878A (zh) 2011-06-15 2012-06-15 识别热量限制标记物和热量限制模拟物

Family Applications After (3)

Application Number Title Priority Date Filing Date
CN202511512713.0A Pending CN121271860A (zh) 2011-06-15 2012-06-15 识别热量限制标记物和热量限制模拟物
CN201280039802.2A Pending CN103732745A (zh) 2011-06-15 2012-06-15 识别热量限制标记物和热量限制模拟物
CN202110890757.2A Pending CN113801878A (zh) 2011-06-15 2012-06-15 识别热量限制标记物和热量限制模拟物

Country Status (6)

Country Link
US (4) US20130178379A1 (https=)
EP (1) EP2721155A4 (https=)
JP (5) JP2014518071A (https=)
KR (1) KR20140041710A (https=)
CN (4) CN107217051A (https=)
WO (1) WO2012174484A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11345963B2 (en) 2018-05-07 2022-05-31 Ebay Inc. Nucleic acid taggants
CN113712121B (zh) * 2021-08-31 2023-08-15 河南牧业经济学院 尼克酰胺在改善泌乳期奶山羊乳成分中的应用
CN119700977B (zh) * 2024-12-11 2025-08-22 山东省妇幼保健院 Psmg4基因在制备心脏疾病治疗药物及相关诊断产品中的应用

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004081537A2 (en) * 2003-03-12 2004-09-23 The Regents Of The University Of California Methods of evaluating caloric restriction and identifying caloric restriction mimetics
WO2006066244A2 (en) * 2004-12-17 2006-06-22 Cash Alan B Method for extending lifespan and delaying the onset of age-related disease
EP1956096A1 (en) * 2007-02-12 2008-08-13 Université Catholique de Louvain Method, device and kit for determining conditions related to a dysfunction of the renal proximal tubule
WO2009135093A2 (en) * 2008-04-30 2009-11-05 Integrated Dna Technologies, Inc. Rnase-h-based assays utilizing modified rna monomers
WO2010005533A2 (en) * 2008-06-30 2010-01-14 The Johns Hopkins University Compositions and methods for the treatment of ocular oxidative stress and retinitis pigmentosa
WO2010104573A1 (en) * 2009-03-11 2010-09-16 Nestec S.A. Tissue-specific aging biomarkers

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6309853B1 (en) * 1994-08-17 2001-10-30 The Rockfeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
PL363426A1 (en) * 2001-03-09 2004-11-15 Societe Des Produits Nestle S.A. Composition improving age-related physiological deficits and increasing longevity
CA2450126A1 (en) * 2001-06-26 2003-01-09 Wisconsin Alumni Research Foundation Gene expression alterations underlying the retardation of aging by caloric restriction in mammals
CA2477911A1 (en) * 2002-03-15 2003-09-25 Max F. Rothschild Novel hmga alleles and use of the same as genetic markers for growth, fatness, meat quality and feed efficiency traits
US7737158B2 (en) * 2005-10-11 2010-06-15 Washington University Processes for regulating blood glucose in a mammal
WO2007088046A2 (en) * 2006-02-01 2007-08-09 Nestec S.A. Nutritional system and methods for increasing longevity
WO2007109102A2 (en) * 2006-03-16 2007-09-27 Biomarker Pharmaceutical Methods for interventions and testing for caloric restriction (cr) mimetics
US20120094300A1 (en) * 2009-04-24 2012-04-19 Robin Shaw Bin1 as a Prognostic Marker in Cardiovascular Disease
JP2012115374A (ja) * 2010-11-30 2012-06-21 Kao Corp Ａｃａｃａ発現抑制方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004081537A2 (en) * 2003-03-12 2004-09-23 The Regents Of The University Of California Methods of evaluating caloric restriction and identifying caloric restriction mimetics
WO2006066244A2 (en) * 2004-12-17 2006-06-22 Cash Alan B Method for extending lifespan and delaying the onset of age-related disease
EP1956096A1 (en) * 2007-02-12 2008-08-13 Université Catholique de Louvain Method, device and kit for determining conditions related to a dysfunction of the renal proximal tubule
WO2009135093A2 (en) * 2008-04-30 2009-11-05 Integrated Dna Technologies, Inc. Rnase-h-based assays utilizing modified rna monomers
WO2010005533A2 (en) * 2008-06-30 2010-01-14 The Johns Hopkins University Compositions and methods for the treatment of ocular oxidative stress and retinitis pigmentosa
WO2010104573A1 (en) * 2009-03-11 2010-09-16 Nestec S.A. Tissue-specific aging biomarkers

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
HARMIT S. RANHOTRA: "Up-regulation of orphan nuclear estrogen-related receptor alpha expression during long-term caloric restriction in mice", 《MOL CELL BIOCHEM》 *
JACEK TURYN等: "Up-regulation of stearoyl-CoA desaturase 1 and elongase 6 genes expression in rat lipogenic tissues by chronic food restriction and chronic food restriction/refeeding", 《MOL CELL BIOCHEM》 *
JEREMY W. CHOPEK等: "Life-long caloric restriction: Effect on age-related changes in motoneuron numbers, sizes and apoptotic markers", 《MECHANISMS OF AGEING AND DEVELOPMENT》 *
RICHARD WEINDRUCH等: "Microarray Profiling of Gene Expression in Aging and Its Alteration by Caloric Restriction in Mice", 《J. NUTR.》 *
WILLIAM R. SWINDELL: "COMPARATIVE ANALYSIS OF MICROARRAY DATA IDENTIFIES COMMON RESPONSES TO CALORIC RESTRICTION AMONG MOUSE TISSUES", 《MECH AGEING DEV》 *
YOSHIKAZU HIGAMI等: "Adipose tissue energy metabolism: altered gene expression profile of mice subjected to long-term caloric restriction", 《THE FASEB JOURNAL》 *

Also Published As

Publication number Publication date
JP6904676B2 (ja) 2021-07-21
WO2012174484A2 (en) 2012-12-20
JP2019037240A (ja) 2019-03-14
JP2021052803A (ja) 2021-04-08
EP2721155A4 (en) 2014-12-31
JP7355766B2 (ja) 2023-10-03
WO2012174484A3 (en) 2013-04-11
JP2016195613A (ja) 2016-11-24
US20160257996A1 (en) 2016-09-08
US20160186257A1 (en) 2016-06-30
JP2022113834A (ja) 2022-08-04
JP2014518071A (ja) 2014-07-28
CN113801878A (zh) 2021-12-17
US20130178379A1 (en) 2013-07-11
CN103732745A (zh) 2014-04-16
EP2721155A2 (en) 2014-04-23
CN121271860A (zh) 2026-01-06
KR20140041710A (ko) 2014-04-04
US20160208330A1 (en) 2016-07-21

Similar Documents

Publication Publication Date Title
US9469875B2 (en) Methods for detection of depressive disorders
JP2022113834A (ja) カロリー制限およびカロリー制限模倣物の同定用マーカー
US20180030539A1 (en) Biomarkers predictive of predisposition to depression and response to treatment
CN106222243B (zh) 一种用于精神分裂症诊断的circRNA标志物、试剂盒及基因芯片
US9732387B2 (en) Biomarker associated with irritable bowel syndrome and Crohn's disease
KR20160127126A (ko) 우울증 및 주요 우울증을 치료하기 위한 방법
CN104946735A (zh) 试剂盒及确定待测dna样本预定snp位点的基因型的方法
JP5427352B2 (ja) ヒト体脂肪量と関連する遺伝子多型に基づく肥満発症リスクの判定方法
US10233501B2 (en) Biomarkers predictive of predisposition to depression and response to treatment
CN104830961B (zh) 用于活体外测定致肥胖风险的方法
US10731219B1 (en) Method for preventing progression to metabolic syndrome
US20190078161A1 (en) Method for identifying clinical trial responders from a placebo group in major depression
WO2004088274A2 (en) Psychoactive compound associated markers and method of use thereof
KR101402919B1 (ko) 중풍 분류용 뉴로펩타이드 ｙ 유전자 다형성 마커 및 이의 용도
CN114350781A (zh) 检测coqr2基因多态性位点snp分型的引物探针组合、试剂盒及其应用
TW201625799A (zh) 治療憂鬱症和重度憂鬱症之方法

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination