CN107213296A - A kind of concocting method of rhizoma arisaematis - Google Patents

A kind of concocting method of rhizoma arisaematis Download PDF

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Publication number
CN107213296A
CN107213296A CN201710489245.9A CN201710489245A CN107213296A CN 107213296 A CN107213296 A CN 107213296A CN 201710489245 A CN201710489245 A CN 201710489245A CN 107213296 A CN107213296 A CN 107213296A
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China
Prior art keywords
rhizoma arisaematis
water
alum
concocting method
ginger
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CN201710489245.9A
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Chinese (zh)
Inventor
朱清山
朱改莲
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Henan Qingshan Pharmaceutical Co Ltd
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Henan Qingshan Pharmaceutical Co Ltd
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Priority to CN201710489245.9A priority Critical patent/CN107213296A/en
Publication of CN107213296A publication Critical patent/CN107213296A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884Arisaema, e.g. Jack in the pulpit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/17Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger

Abstract

A kind of concocting method of rhizoma arisaematis, comprises the following steps:Unprocessed Arisaema erubescens are sieved, cleaning in medicine-washing machine is inserted after stepping, is inserted after cleaning in clean container, obtains net rhizoma arisaematis;Net rhizoma arisaematis is inserted and is soaked in water 26 days in bubble medicine pond, water is changed daily 23 times, a foam is such as played, changed after water plus alum, to cutting opening taste it is micro- have to take out during numb feeling in the tongue put clean container;Ginger slice, alum are put in digester plus after suitable quantity of water boils, the rhizoma arisaematis poured into after immersion takes out when boiling altogether to without the dry heart, removes ginger splices, dry in the air to four to sixty percent dry, put clean container;Rhizoma arisaematis after drying is thinly sliced on medicine cutter, yellow or light brown sheet rhizoma arisaematis is obtained;Rhizoma arisaematis is cut into slices in being dried 57 hours in the stainless steel pallet of 60 80 DEG C of heated-air circulation ovens, water content is less than 12.0% after drying, and cools sieving.The rhizoma arisaematis of processing reduces its toxicity, relaxes its dry strong property, has played the synergy of ginger, alum, the purpose of Synergy and attenuation.

Description

A kind of concocting method of rhizoma arisaematis
Technical field
The invention belongs to technical field of traditional Chinese medicine preparation, and in particular to a kind of concocting method of rhizoma arisaematis.
Background technology
Arisaema Araeceae, Arisaema, also known as tuber of pinellia essence, pinellia pedatisecta Schott, letterwood etc., it is that perennial herb is planted Thing, underground stem tuber is spherical in shape, flat, yellowish-brown, removes fibrous root and crust, is used as medicine with bulb, Arisaema plant tuber is mostly Containing triterpenoid saponin, PEARLITOL 25C, benzoic acid, starch etc., cyanogen glycosides composition, i.e. Triglochin martimum glycosides are still contained in aroid (Triglochinin), rhizoma arisaematis and Arisaema heterophyllum Blume are containing a variety of inorganic members such as amino acid, cupreol and calcium, phosphorus, aluminium, zinc Plain , Gui Amorphophalus rivieris contain saponin, and fruit contains similar coniine(Coniine)Material, Chinese medicine rhizoma arisaematis medicinal history is long, and its name is most Early see the Tang Dynasty Chen Cangqi《Bencao Shiyi》, the effect of with eliminating dampness and eliminating phlegm, expelling wind and relieving convulsion, mass dissipating and swelling eliminating, cure mainly stupid productive cough Cough, facial paralysis, hemiplegia, numb in every limb, epilepsy infantile convulsion, lockjaw, traumatic injury and venomous snake bite etc..
The content of the invention
The invention aims to provide a kind of concocting method of rhizoma arisaematis, reduce its toxicity, its dry property relaxed, with this To strengthen the application in the field of Chinese medicines of rhizoma arisaematis.
A kind of concocting method of rhizoma arisaematis, it is characterised in that comprise the following steps:
Step 1: unprocessed Arisaema erubescens are sieved, cleaned according to being inserted after size stepping in medicine-washing machine, clean container is inserted after cleaning It is interior, net rhizoma arisaematis is obtained, it is standby;
It is soaked in water 2-6 days in bubble medicine pond Step 2: the net rhizoma arisaematis in step one is inserted, water is changed daily 2-3 times, is such as risen white Foam, is changed after water plus alum, to cutting opening taste it is micro- have to take out during numb feeling in the tongue put clean container, it is standby;
Step 3: ginger slice, alum are put in digester plus after suitable quantity of water boils, the rhizoma arisaematis poured into after being soaked in step 2 is total to Taken out when boiling to without the dry heart, remove ginger splices, dried in the air to four to sixty percent dry, put clean container, it is standby;
Step 4: the rhizoma arisaematis after being dried in step 3 is thinly sliced on medicine cutter, yellow or light brown sheet day are obtained Southern Star, it is standby;
Step 5: it is small in drying 5-7 in the stainless steel pallet of 60-80 DEG C of heated-air circulation oven that rhizoma arisaematis in step 4 is cut into slices When, water content is less than 12.0% after drying, and cools sieving.
Stepping is divided into large, medium and small three shelves in further optimization, the step one, and diameter dimension is respectively 4.5- 6.5cm、3-4.5cm、1.5-3cm。
Further optimization, the step one storage temperature into step 4 is 10~30 DEG C, and relative humidity is 45~75%,
Net container in further optimization, the step one is plastic box or stainless steel cask.
Rhizoma arisaematis summer soaks 2-3 days in further optimization, the step 2, and winter soaks 5-6 days
The consumption of alum is per 100kg rhizoma arisaematis, plus alum 2kg in further optimization, the step 2.
In further optimization, the step 3 during boiling, ginger 12.5kg, alum 10.5kg are added per 100kg rhizoma arisaematis.
Rhizoma arisaematis slice thickness is 1-2mm in further optimization, the step 4.
Rhizoma arisaematis is 1.5-2.5cm in the feeding thickness of stainless steel pallet in further optimization, the step 5.
The beneficial effects of the invention are as follows:
First, rhizoma arisaematis is by the synergy that can detoxify after alum, ginger processing, and its detoxification mechanism is absorption poisonous substance, changes the reason of poisonous substance Change property, physiologically active and enhancing body detoxification ability, prolonged water process can significantly decrease rhizoma arisaematis water leachable and The amount of lead acetate sediment in alcohol leachable;
2nd, the method for Rhizoma Arisaematis (processed) continues to use clear water immersion, plus the well-done heart of ginger, alum, the technique of chip drying, long-time mostly Water immersion and boil, toxicity can be no doubt removed, but therefore also result in the loss of active ingredient, therefore, big gun of adopting new technology Rhizoma Arisaematis (processed) piece, i.e., only soaked with clear water, rise foam when, plus alum processing, to mouth taste it is micro- have numb feeling in the tongue when take out, dry, cut into slices, Toxicity not only can be effectively removed, active ingredient loss is decreased;
3rd, the rhizoma arisaematis before processing contains a large amount of noxious materials, and calcium oxalate therein is main pungent toxic component, and alum is not Only it is the crucial auxiliary material of reduction or elimination rhizoma arisaematis toxic side effect, the numb bitter taste of rhizoma arisaematis can also be removed, ginger can be made Acted synergistically for removing toxic substances material with alum;
In summary, the rhizoma arisaematis of processing reduces its toxicity, relaxes its dry strong property, has played the synergy of ginger, alum, The purpose of Synergy and attenuation.
Embodiment
Embodiment 1
A kind of concocting method of rhizoma arisaematis, it is characterised in that comprise the following steps:
Step 1: taking 1kg unprocessed Arisaema erubescens to sieve, cleaned according to being put into after large, medium and small third gear stepping in medicine-washing machine, after cleaning Rhizoma arisaematis insert in clean container, obtain net rhizoma arisaematis, it is standby;
It is soaked in water Step 2: the net rhizoma arisaematis in step one is inserted in bubble medicine pond, summer soak time is 2 days, winter leaching The bubble time is 5 days, in order to prevent rhizoma arisaematis from rotting, it is mouldy etc. influence its drug effect, water is changed daily 2 times, such as plays a foam, change water Afterwards plus alum 0.02kg, to cutting opening taste it is micro- have to take out during numb feeling in the tongue put clean container, it is standby;
Step 3: 0.125kg ginger slices, 0.105kg alums are put in digester plus after suitable quantity of water boils, pour into step 2 and soak Rhizoma arisaematis after bubble takes out when boiling altogether to without the dry heart, removes ginger splices, dries in the air to four to sixty percent dry, puts clean container, standby;
Step 4: the rhizoma arisaematis after being dried in step 3 is cut into thickness on medicine cutter for 1mm thin slices, yellow is obtained or light brown Color chips shape rhizoma arisaematis, it is standby;
Step 5: rhizoma arisaematis in step 4 is cut into slices in drying 5 hours in the stainless steel pallet of 60 DEG C of heated-air circulation ovens, in order to The feeding thickness for reaching rhizoma arisaematis in uniformly dry effect, pallet is 1.5cm, and its water content is measured after drying less than 12.0%, Cool sieving.
Further optimization, stepping is divided into large, medium and small three shelves in the step one, diameter dimension be respectively 4.5cm, 3cm、1.5cm。
Further optimization, the step one storage temperature into step 4 is 10 DEG C, and relative humidity is 45%,
Net container in further optimization, the step one is plastic box or stainless steel cask.
Embodiment 2
A kind of concocting method of rhizoma arisaematis, it is characterised in that comprise the following steps:
Step 1: taking 1kg unprocessed Arisaema erubescens to sieve, cleaned according to being put into after large, medium and small third gear stepping in medicine-washing machine, after cleaning Rhizoma arisaematis insert in clean container, obtain net rhizoma arisaematis, it is standby;
It is soaked in water Step 2: the net rhizoma arisaematis in step one is inserted in bubble medicine pond, summer soak time is 2.5 days, winter Soak time is 5.5 days, in order to prevent rhizoma arisaematis from rotting, it is mouldy etc. influence its drug effect, need to change water 2 daily during soaking It is secondary, such as play a foam, change after water plus alum 0.02kg, to cutting opening taste it is micro- have to take out during numb feeling in the tongue put clean container, it is standby;
Step 3: 0.125kg ginger slices, 0.105kg alums are put in digester plus after suitable quantity of water boils, pour into step 2 and soak Rhizoma arisaematis after bubble takes out when boiling altogether to without the dry heart, removes ginger splices, dries in the air to four to sixty percent dry, puts clean container, standby;
Step 4: the rhizoma arisaematis after being dried in step 3 is cut into thickness on medicine cutter for 1.5mm thin slices, yellow is obtained or light Brown sheet rhizoma arisaematis, it is standby;
Step 5: rhizoma arisaematis in step 4 is cut into slices in drying 6 hours in the stainless steel pallet of 70 DEG C of heated-air circulation ovens, in order to The feeding thickness for reaching rhizoma arisaematis in uniformly dry effect, pallet is 2cm, and its water content is measured after drying less than 12.0%, is put Cool sieving.
Further optimization, stepping is divided into large, medium and small three shelves in the step one, diameter dimension be respectively 5.5cm, 4cm、2.5cm。
Further optimization, the step one storage temperature into step 4 is 20 DEG C, and relative humidity is 60%.
Net container in further optimization, the step one is plastic box or stainless steel cask.
Embodiment 3
A kind of concocting method of rhizoma arisaematis, it is characterised in that comprise the following steps:
Step 1: taking 1kg unprocessed Arisaema erubescens to sieve, cleaned according to being put into after large, medium and small third gear stepping in medicine-washing machine, after cleaning Rhizoma arisaematis insert in clean container, obtain net rhizoma arisaematis, it is standby;
It is soaked in water Step 2: the net rhizoma arisaematis in step one is inserted in bubble medicine pond, summer soak time is 3 days, winter leaching The bubble time is 6 days, in order to prevent rhizoma arisaematis from rotting, it is mouldy etc. influence its drug effect, water is changed daily 3 times, such as plays a foam, change water Afterwards plus alum 0.02kg, to cutting opening taste it is micro- have to take out during numb feeling in the tongue put clean container, it is standby;
Step 3: 0.125kg ginger slices, 0.105kg alums are put in digester plus after suitable quantity of water boils, pour into step 2 and soak Rhizoma arisaematis after bubble takes out when boiling altogether to without the dry heart, removes ginger splices, dries in the air to four to sixty percent dry, puts clean container, standby;
Step 4: the rhizoma arisaematis after being dried in step 3 is cut into thickness on medicine cutter for 2mm thin slices, yellow is obtained or light brown Color chips shape rhizoma arisaematis, it is standby;
Step 5: rhizoma arisaematis in step 4 is cut into slices in drying 7 hours in the stainless steel pallet of 80 DEG C of heated-air circulation ovens, in order to The feeding thickness for reaching rhizoma arisaematis in uniformly dry effect, pallet is 2.5cm, and its water content is measured after drying less than 12.0%, Cool sieving.
Further optimization, stepping is divided into large, medium and small three shelves in the step one, diameter dimension be respectively 6.5cm, 4.5cm、3cm。
Further optimization, the step one storage temperature into step 4 is 30 DEG C, and relative humidity is 75%,
Net container in further optimization, the step one is plastic box or stainless steel cask.
Embodiment 4
Summer soak time is 4 days in step 2, and winter soak time is 7 days, remaining step of preparation process and the phase of embodiment 3 Together.
Embodiment 5
Summer soak time is 5 days in step 2, and winter soak time is 8 days, remaining step of preparation process and the phase of embodiment 3 Together.
Embodiment 6
Alum, the ginger consumption of step 3 in embodiment 3 are removed, remaining step of preparation process is identical.
Rhizoma arisaematis before processing contains a large amount of noxious materials, and calcium oxalate therein is main pungent toxic component, alum It is the crucial auxiliary material of reduction or elimination rhizoma arisaematis toxic side effect, ginger acts not only as removing toxic substances material and acted synergistically with alum, The bitter taste of rhizoma arisaematis can also be removed, in addition, the content of calcium oxalate also there are much relations with soak time, below according to mouth Sense and needle-like calcium oxalate crystal content are compared.
Needle-like calcium oxalate crystal content after the processing of the rhizoma arisaematis of table 1
It can be observed from table 1 that the content of the rhizoma arisaematis needle-like calcium oxalate crystal after being processed using alum, ginger is substantially reduced, implement The needle-like calcium oxalate crystal content of example 6 is twice or so of embodiment 1-5, because alum plays master with ginger during processing The disinfective action wanted;Embodiment 4-5 needle-like calcium oxalate crystal content is raised on a small quantity compared with embodiment 3, be because long soaking time, from And cause the needle-like calcium oxalate crystal not destroyed on a small quantity to be relapsed by rhizoma arisaematis.
Principal character, application method, general principle and the advantages of the present invention of the present invention has been shown and described above.This Industry technology personnel it should be appreciated that the present invention is not limited to the above embodiments, described in above-described embodiment and invention book only It is the principle of the present invention, without departing from the spirit and scope of the present invention, the present invention can also have various according to actual conditions Changes and improvements, these changes and improvements all fall within the protetion scope of the claimed invention.The claimed scope of the invention is by institute Attached claims and its equivalent thereof.

Claims (9)

1. a kind of concocting method of rhizoma arisaematis, it is characterised in that comprise the following steps:
Step 1: unprocessed Arisaema erubescens are sieved, cleaned according to being inserted after size stepping in medicine-washing machine, clean container is inserted after cleaning It is interior, net rhizoma arisaematis is obtained, it is standby;
It is soaked in water 2-6 days in bubble medicine pond Step 2: the net rhizoma arisaematis in step one is inserted, water is changed daily 2-3 times, is such as risen white Foam, is changed after water plus alum, to cutting opening taste it is micro- have to take out during numb feeling in the tongue put clean container, it is standby;
Step 3: ginger slice, alum are put in digester plus after suitable quantity of water boils, the rhizoma arisaematis poured into after being soaked in step 2 is total to Taken out when boiling to without the dry heart, remove ginger splices, dried in the air to four to sixty percent dry, put clean container, it is standby;
Step 4: the rhizoma arisaematis after being dried in step 3 is thinly sliced on medicine cutter, yellow or light brown sheet day are obtained Southern Star, it is standby;
Step 5: it is small in drying 5-7 in the stainless steel pallet of 60-80 DEG C of heated-air circulation oven that rhizoma arisaematis in step 4 is cut into slices When, water content is less than 12.0% after drying, and cools sieving.
2. a kind of concocting method of rhizoma arisaematis according to claim 1, it is characterised in that stepping is divided into the step one Large, medium and small three shelves, size is respectively to be more than 5cm, 3-5cm, 0-3cm.
3. a kind of concocting method of rhizoma arisaematis according to claim 1, it is characterised in that the step one is stored up into step 4 It is 10~30 DEG C to deposit temperature, and relative humidity is 45~75%.
4. a kind of concocting method of rhizoma arisaematis according to claim 1, it is characterised in that the net container in the step one is Plastic box or stainless steel cask.
5. a kind of concocting method of rhizoma arisaematis according to claim 1, it is characterised in that rhizoma arisaematis summer in the step 2 Immersion 2-3 days, winter soaks 5-6 days.
6. a kind of concocting method of rhizoma arisaematis according to claim 1, it is characterised in that the consumption of alum in the step 2 For every 100kg rhizoma arisaematis, plus alum 2kg.
7. a kind of concocting method of rhizoma arisaematis according to claim 1, it is characterised in that in the step 3 during boiling, often 100kg rhizoma arisaematis adds ginger 12.5kg, alum 10.5kg.
8. a kind of concocting method of rhizoma arisaematis according to claim 1, it is characterised in that rhizoma arisaematis is cut into slices in the step 4 Thickness is 1-2mm.
9. a kind of concocting method of rhizoma arisaematis according to claim 1, it is characterised in that rhizoma arisaematis is not in the step 5 The feeding thickness of rust steel tray is 1.5-2.5cm.
CN201710489245.9A 2017-06-24 2017-06-24 A kind of concocting method of rhizoma arisaematis Pending CN107213296A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107596040A (en) * 2017-10-13 2018-01-19 河南省三禾药业有限公司 A kind of rhizoma arisaematis processed product and its concocting method
CN108926647A (en) * 2018-08-15 2018-12-04 康美滕王阁(四川)制药有限公司 A kind of rhizoma arisaematis processing procedure and products thereof
CN110477046A (en) * 2019-07-08 2019-11-22 亳州中量万峰生物科技有限公司 A kind of Pesticide with Chinese medicinal material and preparation method thereof
CN111388581A (en) * 2019-11-29 2020-07-10 浙江桐君堂中药饮片有限公司 Preparation method of processed rhizoma arisaematis
CN111407833A (en) * 2019-11-29 2020-07-14 浙江桐君堂中药饮片有限公司 Preparation method of arisaema cum bile
CN114617926A (en) * 2022-02-28 2022-06-14 四川香雪制药有限公司 Processing method of rhizoma arisaematis

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107596040A (en) * 2017-10-13 2018-01-19 河南省三禾药业有限公司 A kind of rhizoma arisaematis processed product and its concocting method
CN108926647A (en) * 2018-08-15 2018-12-04 康美滕王阁(四川)制药有限公司 A kind of rhizoma arisaematis processing procedure and products thereof
CN110477046A (en) * 2019-07-08 2019-11-22 亳州中量万峰生物科技有限公司 A kind of Pesticide with Chinese medicinal material and preparation method thereof
CN111388581A (en) * 2019-11-29 2020-07-10 浙江桐君堂中药饮片有限公司 Preparation method of processed rhizoma arisaematis
CN111407833A (en) * 2019-11-29 2020-07-14 浙江桐君堂中药饮片有限公司 Preparation method of arisaema cum bile
CN111407833B (en) * 2019-11-29 2021-11-16 浙江桐君堂中药饮片有限公司 Preparation method of arisaema cum bile
CN114617926A (en) * 2022-02-28 2022-06-14 四川香雪制药有限公司 Processing method of rhizoma arisaematis

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Application publication date: 20170929