CN107184663A - A kind of Chinese medicine composition for treating renal failure - Google Patents
A kind of Chinese medicine composition for treating renal failure Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract
A kind of Chinese medicine composition for treating renal failure disclosed by the invention, is related to technical field of Chinese medicine, is prepared from by following raw material by weight：Chinese cassia tree 5 15, the bark of eucommia 5 15, Semen Cuscutae 10 20, the rhizome of davallia 5 15, the Radix Astragali 15 25, Lasiosphaera fenzlii 0.5 2, Asiatic plantain 5 15, Caulis Perillae 5 15, ganoderma lucidum 5 15, radix pseudostellariae 15, juglandis,semen 5 15, cordyceps sinensis 0.2 1, cynomorium songaricum 5 15, spongilla 0.5 2, Chinese parasol tree seed 38.With mends fire supporing yang, tonify the liver and kidney, invigorating qi for strengthening superficies, diuretic and maintain drug, removing heat from the lung and relieving sorethroat, reducing fever and causing diuresis, excreting dampness antidiarrheal, pleasant and stomach, reinforcing spleen to promote digestion, help spleen and lung, nourishing generate fluid, the strong kidney of moistening lung, invigorate the lung and the kidney the effects such as, there is good therapeutic effect to all diseases of renal failure, be suitable for treating the renal failure symptom in each stage.
Description
Art
The present invention relates to technical field of Chinese medicine, particularly a kind of Chinese medicine composition for treating renal failure.
Background technology
Chronic renal failure (chronic renal failure, CRF) refers to slowly enter caused by various kidney troubles
Row kidney function damage, finally results in uremia and renal function completely loses, and causes a series of clinical symptoms and biochemical, endocrine
The clinical syndrome constituted Deng metabolic disorder.Since protopathy onset to renal insufficiency, interval time can arrive for the several years
More than ten years.Chronic renal failure is divided into by 4 phases according to the degree of kidney function damage：1. kidney Reserved function declines, and patient is without disease
Shape；2. compensatory stage of renal insufficiency；3. renal function Decompensated stage (azotemia phase), patient has weak, poor appetite and anaemia；
4. uremic phase, there is symptoms of uremia.
At present, the medicine for the treatment of renal failure is more, such as：" NIAODUQING KELI " that Kang Chen medicine companies are produced, Chinese medicinal material industry of reviving
" Huang Kui capsule " produced, " Yinhua Miyanling tablet " that magnificent health medicine company is produced, " shenyankangfu tablet " that Tongrentang produces, Beijing ten thousand
" α keto acid compound " that crude drug industry is produced, " Hai Kun Sheng Xi Capsule " that Huinan long queue biochemistry medicine company is produced, deer king pharmacy is produced
" ephritis relax piece " etc..
Chinese patent " a kind of to treat Chinese medicine composition of kidney failure diseases and preparation method thereof " (patent No. application
For：200910309173.0), mainly it is made up of following bulk drug:The fruit of Chinese wolfberry, American Ginseng, Radix Codonopsis, the raw Radix Astragali, pilose antler, Chinese yam,
Hippocampus, Morinda officinalis, cordyceps sinensis, ganoderma lucidum, Semen Cuscutae, Gorgon fruit, the bark of eucommia, prepared rhizome of rehmannia, Radix Angelicae Sinensis, the root of herbaceous peony, lucid asparagus, the fruit of glossy privet, Huang
Cypress, Poria cocos, cape jasmine, plantain seed, desmodium, talcum, rhizoma alismatis.
(number of patent application is for another Chinese patent " one kind treats uremic Chinese medicine composition "：
201310555236.7), it is made up of following weight part ratio component：15 parts of Poria cocos, 12 parts of the root of herbaceous peony, 4.5 parts of the coptis, 9 parts of perilla leaf,
15 parts of umbellate pore furgus, 15 parts of rhizoma alismatis, 12 parts of ginger, 15 parts of RADIX ACONITI LATERALIS PREPARATA, 30 parts of motherwort, 15 parts of the bighead atractylodes rhizome, 15 parts of radix pseudostellariae, the Radix Astragali 15
Part, 15 parts of the red sage root, 15 parts of Radix Achyranthis Bidentatae, 15 parts of stringy stonecrop, 15 parts of Chinese violet, 15 parts of rhizoma imperatae, 12 parts of the bark of eucommia, rhubarb 15
Part, 6 parts of cordyceps.
The content of the invention
The technical problems to be solved by the invention be to provide it is a kind of have mends fire supporing yang, tonify the liver and kidney, invigorating qi for strengthening superficies, diuresis
Eliminating toxic, removing heat from the lung and relieving sorethroat, reducing fever and causing diuresis, excreting dampness antidiarrheal, pleasant and stomach, reinforcing spleen to promote digestion, help spleen and lung, nourishing generate fluid, the strong kidney of moistening lung,
The effects such as invigorating the lung and the kidney, the Chinese medicine for having good therapeutic effect to all diseases of renal failure.
Treated in order to solve the above technical problems, the technical solution used in the present invention invention is a kind of in renal failure
Drug composition, is prepared from by following raw material by weight：
Its technical scheme one optimized is prepared from by following raw material by weight：
Its technical scheme two optimized is prepared from by following raw material by weight：
Its technical scheme three optimized is prepared from by following raw material by weight：
At the same time, a kind of preparation method for the Chinese medicine composition for treating renal failure is also provided, its preparation process is such as
Under：
A, get the raw materials ready：According to above-mentioned weight, choose Chinese cassia tree, the bark of eucommia, Semen Cuscutae, the rhizome of davallia, the Radix Astragali, horse respectively
Suddenly, Asiatic plantain, Caulis Perillae, ganoderma lucidum, cynomorium songaricum, spongilla, Chinese parasol tree seed, radix pseudostellariae, juglandis,semen, cordyceps sinensis, standby；
B, decoction are extracted：First by Chinese cassia tree, the bark of eucommia, Semen Cuscutae, the rhizome of davallia, the Radix Astragali, Lasiosphaera fenzlii, Asiatic plantain, Caulis Perillae, ganoderma lucidum,
Cynomorium songaricum, spongilla, Chinese parasol tree seed are placed in container, are added the clear water of 1-3 times of weight, are decocted into the decoction of 0.5-1 times of weight, such two
It is secondary, merge decoction twice, it is standby as decoction is extracted；
C, medicinal powder are produced：Radix pseudostellariae, juglandis,semen, cordyceps sinensis are respectively crushed into the medicinal powder of 100-150 mesh, it is standby；
D, mixing：By medicinal powder be added to extraction decoction in, be well mixed, treatment renal failure Chinese medicine composition
(decoction).
Further, treatment is made by concentrating in the Chinese medicine composition of well mixed treatment renal failure
The traditional Chinese medicine particle electuary or extract of renal failure filling into capsule or are pressed into tablet.
Theory of traditional Chinese medical science thinks：The pathogenesis of renal failure is lost for this with spleen renal failure, causes lung, spleen, the dirty function of kidney three disorderly
Disorderly, performance strength, blood, the deficiency of yin, yang, while having wet turbid, the damp and hot, complexity such as poison, aqueous vapor, hemostasis, liver wind, wind-dryness of drowning concurrently
Real example is marked to wait.The rules for the treatment of：Clearing heat and promoting diuresis, tonifying speen and tonifying kidney, harmonizing stomach and lowering adverse Qi.
The Chinese medicine composition of the treatment renal failure of the present invention, the Chinese medicine of use mainly have Chinese cassia tree, the bark of eucommia, Semen Cuscutae,
The rhizome of davallia, the Radix Astragali, Lasiosphaera fenzlii, Asiatic plantain, Caulis Perillae, ganoderma lucidum, cynomorium songaricum, spongilla, Chinese parasol tree seed, radix pseudostellariae, juglandis,semen, worm summer in winter
Grass.
Chinese cassia tree [Cinnamomum cassia Presl] is pungent, sweet, big heat, returns kidney, spleen, the heart, Liver Channel, with mends fire supporing yang,
The effect of let the fire back to its origin, eliminating cold to stop pain, invigorate blood circulation, for impotence, Gong Leng, waist and knee crymodynia, deficiency of the kidney and dyspnea, dizziness due to yang deficiency, mesh
Red pharyngalgia, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea, cold hernia, run quickly globefish, Amenorrhea, the disease such as dysmenorrhoea.
It is sweet, warm-natured for the bark of eucommia [Eucommia ulmoides Oliver].Tonify the liver and kidney, strengthen muscles and bones, nursing one's health punching
Appoint, effect of strengthen meridian and miscarriage prevention.
Semen Cuscutae [Cuscuta chinensis Lam.] smell is pungent, sweet, puts down, nontoxic.Tonifying kidney and benefiting sperm, nourishes the liver to improve visual acuity.
The rhizome of davallia [Drynariafortunei (Kze.) J.Sm.] is bitter, temperature.Return kidney, Liver Channel.The strong bone of kidney tonifying, continues and hinders pain relieving.
For lumbago due to the kidney deficiency, kidney deficiency chronic diarrhea, Hiccough and deaf, tooth mobility, falling winks frustrates, injured bone.
The Radix Astragali [Astragalus membranaceus (Fisch.) or Astragalus membranaceus (Fisch.)
Bge.var.mongholicus (Bge.) Hsiao] sweet, tepor.Return lung, spleen, liver and kidney channel.With invigorating qi for strengthening superficies, diuretic and maintain drug,
Apocenosis, effect of expelling pus and promoting granulation.For treatment deficiency of vital energy weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency from
Sweat, ulcer is difficult to burst, burst for a long time and does not holds back, blood deficiency chlorosis, Heat Diabetes.
Lasiosphaera fenzlii [LASIOSPHAERA SEU CALVATIA] is pungent, flat, nontoxic.Removing heat from the lung and relieving sorethroat, removing toxic substances hemostasis.Main throat swells
Bitterly, cough with aphonia, hematemesis and epistaxis, all sores are not held back.
Asiatic plantain [Plantago asiatica] is sweet, light, cold nature.Return lung is passed through, Liver Channel, kidney channel, bladder warp.Function：Clearly
Hot diuresis, excreting dampness antidiarrheal, improving eyesight, eliminating the phlegm.Cure mainly：Under main difficult urination, stranguria with turbid discharge band, oedema turgor, summer-heat and damp rush down dysentery, hot eyes barrier
Screen, the hot cough and asthma of phlegm.
Caulis Perillae [Perilla frutescens (L.) Britton.] Xin Gan, tepor is nontoxic, enters spleen, stomach, the warp of lung three.
Function is cured mainly：It is soothing the liver, sharp lung, qi-regulating, and blood, Xie Yu, analgesic, cough surely, it is antiabortive.
Ganoderma lucidum [Ganoderma Lucidum Karst] is sweet mild-natured, enters the heart channel of Hang-Shaoyin, major function is had no peace of mind, and has a sleepless night, and shies
Throb with fear.Can control insufficiency of vital energy and blood, the mind lose support it is caused have no peace of mind, have a sleepless night, palpitating with fear, dreaminess, the disease such as the tired tired, deficiency of food of god of forgetful, body.
Cynomorium songaricum [Cynomorium songaricum Rupr.] is sweet, temperature, nontoxic.Big tonifying yin gas, benefiting essence-blood, profit stool.Energy
Kidney tonifying, strengthening the essence, moisturize, cure mainly impotence and seminal emission, soreness and weakness of waist and knees, dry constipation of intestines, sexual performance is weak certain to paralysing and improving
Effect.
Spongilla [Spongilla fragilis Lecidy or Ephydatia muelleri var.japonica
(Hilgendorf)] sweet, temperature is nontoxic.Kidney tonifying, strengthening the essence is supporing yang.
Chinese parasol tree seed [Firmiana platanifolia (L.f.) Marsili [F.simplex (L.) W.F.Wight] bitter
It is pungent, it is warm-natured, it is nontoxic.The thoughts of returning home, lung, stomach.Effect is pleasant and stomach；Reinforcing spleen to promote digestion；Hemostasis.
Radix pseudostellariae [Pseudostellaria heterophylla (Miq.) Pax ex Pax et Hoffm.] is sweet, micro-
Hardship, puts down.Enter the heart, spleen, the warp of lung three.Effect：Help spleen and lung, nourishing generate fluid.
Juglandis,semen [Juglans regia L.] nature and flavor are sweet, temperature.Return kidney, lung, large intestine channel.With the strong kidney of moistening lung, reduction blood
The effect of fat, prevention coronary heart disease, for soreness and weakness of waist and knees, impotence and seminal emission, the cold of insufficiency type, which is breathed heavily, coughs, constipation.
Cordyceps sinensis [Ophiocordyceps sinensis] nature and flavor are sweet, temperature.Function is invigorated the lung and the kidney, preventing phlegm from forming and stopping coughing.According to grinding
Study carefully：Cordyceps sinensis mainly contains the compositions such as Cordycepin, cordyceps sinensis cordyceps sinensis acid, adenosine and polysaccharide；Cordycepin can press down
The growth of the germs such as streptococcus processed, Actinobacillus mallei bacillus anthracis, is the active material of anticancer again, to the internal system of human body and
The adjustment effect that nervous system has had；Cordycepic acid can change microcirculation in human body, with obvious reducing blood lipid and Antitussive and Expectorant Effect；
Cordyceps sinensis polysaccharide is immunomodulator, can strengthen body to virus and the resistance of parasite.
Above-mentioned all medicines share so that the Chinese medicine composition for the treatment of renal failure of the invention, with mends fire supporing yang, help
Liver kidney, invigorating qi for strengthening superficies, diuretic and maintain drug, removing heat from the lung and relieving sorethroat, reducing fever and causing diuresis, excreting dampness antidiarrheal, pleasant and stomach, reinforcing spleen to promote digestion, help spleen and lung,
Nourishing generate fluid, the strong kidney of moistening lung, the effects such as invigorate the lung and the kidney, can clearing heat and promoting diuresis, tonifying speen and tonifying kidney, harmonizing stomach and lowering adverse Qi, thus, to renal function
The all diseases of exhaustion have good therapeutic effect.
The Chinese medicine composition of the treatment renal failure of the present invention, once did therapeutic test to all diseases of renal failure：
(i), testing crew general information
The patients with renal failure 150 made a definite diagnosis through hospital is selected, wherein：Male 80, women 70；Age 11~63
Year.
(ii), test method
(1), take orally：Using the present invention treatment renal failure Chinese medicine composition (i.e.：Extract and mixed medicine
Liquid), twice daily, early, supper half an hour after is 150ml each taking consumption.
(2), the course for the treatment of：It is within every 90 days to be counted after course for the treatment of, 8 courses for the treatment of.
(3), points for attention：During medication, fasting beans, fresh-water fishes, spiral shell, shrimps and marine product group food.
(iii), curative effect determinate standard：
(1), cure：The edema of the face, edema of limbs are wholly absent, and diet is normal, and spirit is shaken greatly, the retention of urine, creatinine, albumen
Urinate indices completely normal.Index for examination keeps normal after half a year, and sign improves completely, and patient is without any bad sensation.
(2), take a turn for the better：The edema of the face, edema of limbs improve, and diet is normal, and spirit is shaken greatly, and the retention of urine, creatinine, albuminuria are each
Item index is improved in varying degrees.
(3) it is, invalid：Sign changes without any, and sumptom is the same as before, and indices are unchanged or without obvious change.
Cure and take a turn for the better and be included in effective statistics.
(iv), result of the test
By the experiment of 8 courses for the treatment of, statistics see the table below：
Healing 102 is can be seen that from upper table data, is taken a turn for the better 41, invalid 7, its effective percentage is 95.3%, it is seen then that
The Chinese medicine composition of the treatment renal failure of the present invention has preferable curative effect to each stage of renal failure.
Embodiment
With reference to embodiments, the present invention is further illustrated.Following explanation is but this hair in the way of enumerating
Bright protection domain is not limited thereto.
Embodiment one：
The Chinese medicine composition of the treatment renal failure of the present invention, its preparation process is as follows：
A, get the raw materials ready：Take respectively by weight 5 parts of Chinese cassia tree, 15 parts of the bark of eucommia, 10 parts of Semen Cuscutae, 5 parts of the rhizome of davallia, 25 parts of the Radix Astragali,
0.5 part of Lasiosphaera fenzlii, 5 parts of Asiatic plantain, 15 parts of Caulis Perillae, 15 parts of ganoderma lucidum, 5 parts of radix pseudostellariae, 5 parts of juglandis,semen, 0.2 part of cordyceps sinensis, lock
15 parts of sun, 0.5 part of spongilla, 3 parts of Chinese parasol tree seed, it is standby；
B, decoction are extracted：By Chinese cassia tree, the bark of eucommia, Semen Cuscutae, the rhizome of davallia, the Radix Astragali, Lasiosphaera fenzlii, Asiatic plantain, Caulis Perillae, ganoderma lucidum, lock
Sun, spongilla, Chinese parasol tree seed are placed in container, are added the clear water of 2 times of weight, are decocted into the decoction of 0.8 times of weight, so twice, are closed
And decoction twice, it is standby as decoction is extracted；
C, medicinal powder are produced：Radix pseudostellariae, juglandis,semen, cordyceps sinensis are respectively crushed into the medicinal powder of 120 mesh, it is standby；
D, mixing：By medicinal powder be added to extraction decoction in, be well mixed, treatment renal failure Chinese traditional medicine composition
Thing.
Its treatment method is identical with experiment above method.
Embodiment two：
Take 15 parts of Chinese cassia tree, 5 parts of the bark of eucommia, 20 parts of Semen Cuscutae, 15 parts of the rhizome of davallia, 15 parts of the Radix Astragali, Lasiosphaera fenzlii 2 respectively by weight
Part, 15 parts of Asiatic plantain, 5 parts of Caulis Perillae, 5 parts of ganoderma lucidum, 1 part of radix pseudostellariae, 15 parts of juglandis,semen, 1 part of cordyceps sinensis, 5 parts of cynomorium songaricum, purple clouds
2 parts, 8 parts of Chinese parasol tree seed are spent, it is other identical with embodiment one.
Embodiment three：
Take 10 parts of Chinese cassia tree, 10 parts of the bark of eucommia, 15 parts of Semen Cuscutae, 10 parts of the rhizome of davallia, 20 parts of the Radix Astragali, Lasiosphaera fenzlii 1 respectively by weight
Part, 10 parts of Asiatic plantain, 10 parts of Caulis Perillae, 10 parts of ganoderma lucidum, 3 parts of radix pseudostellariae, 10 parts of juglandis,semen, 0.5 part of cordyceps sinensis, cynomorium songaricum 10
Part, 1 part of spongilla, 5 parts of Chinese parasol tree seed are other identical with embodiment one.
The Chinese medicine composition of the treatment renal failure of the present invention, is suitable for treating the renal failure in each stage
Shape.
Claims (6)
1. a kind of Chinese medicine composition for treating renal failure, it is characterised in that be prepared by following raw material by weight and
Into：
2. according to claim 1 treat renal failure Chinese medicine composition, it is characterised in that be by it is following by weight
Raw material be prepared from：
3. according to claim 1 treat renal failure Chinese medicine composition, it is characterised in that be by it is following by weight
Raw material be prepared from：
4. according to claim 1 treat renal failure Chinese medicine composition, it is characterised in that be by it is following by weight
Raw material be prepared from：
5. a kind of preparation method for the Chinese medicine composition that renal failure is treated as any one of claim 1-4, it is special
Levy and be that preparation process is as follows：
A, get the raw materials ready：According to above-mentioned weight, choose Chinese cassia tree, the bark of eucommia, Semen Cuscutae, the rhizome of davallia, the Radix Astragali, Lasiosphaera fenzlii, car respectively
Preceding grass, Caulis Perillae, ganoderma lucidum, cynomorium songaricum, spongilla, Chinese parasol tree seed, radix pseudostellariae, juglandis,semen, cordyceps sinensis, it is standby；
B, decoction are extracted：First by Chinese cassia tree, the bark of eucommia, Semen Cuscutae, the rhizome of davallia, the Radix Astragali, Lasiosphaera fenzlii, Asiatic plantain, Caulis Perillae, ganoderma lucidum, cynomorium songaricum,
Spongilla, Chinese parasol tree seed are placed in container, are added the clear water of 1-3 times of weight, are decocted into the decoction of 0.5-1 times of weight, so twice, are closed
And decoction twice, it is standby as decoction is extracted；
C, medicinal powder are produced：Radix pseudostellariae, juglandis,semen, cordyceps sinensis are respectively crushed into the medicinal powder of 100-150 mesh, it is standby；
D, mixing：By medicinal powder be added to extraction decoction in, be well mixed, treatment renal failure Chinese medicine composition.
6. the preparation method of the Chinese medicine composition of renal failure is treated according to claim 5, it is characterised in that：Will mixing
The Chinese medicine composition for the treatment of renal failure is made by concentration in the Chinese medicine composition for the treatment of renal failure uniformly
Grain electuary or extract filling into capsule or are pressed into tablet.
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105125814A (en) * | 2015-10-19 | 2015-12-09 | 管遵信 | Traditional Chinese medicine composite for treating chronic renal failure III and IV stages |
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- 2017-05-24 CN CN201710375474.8A patent/CN107184663A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105125814A (en) * | 2015-10-19 | 2015-12-09 | 管遵信 | Traditional Chinese medicine composite for treating chronic renal failure III and IV stages |
Non-Patent Citations (1)
| Title |
|---|
| 曾宇晖: "综合治疗慢性肾功能衰竭20例总结", 《湖南中医杂志》 * |
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Inventor after: Chen Guoqing Inventor after: Chen Xiwang Inventor after: Peng Shuangyun Inventor before: Chen Guoqing Inventor before: Chen Xiwang |
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Application publication date: 20170922 |