CN107174639A - Treat the Chinese medicine composition of cardiovascular disease - Google Patents
Treat the Chinese medicine composition of cardiovascular disease Download PDFInfo
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- CN107174639A CN107174639A CN201710543426.5A CN201710543426A CN107174639A CN 107174639 A CN107174639 A CN 107174639A CN 201710543426 A CN201710543426 A CN 201710543426A CN 107174639 A CN107174639 A CN 107174639A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/41—Crassulaceae (Stonecrop family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8967—Lilium, e.g. tiger lily or Easter lily
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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Abstract
The invention discloses a kind of Chinese medicine composition for treating cardiovascular disease, it is characterised in that by weight, is made up of following raw material：12 15 parts of rhodiola root, 12 15 parts of the red sage root, 58 parts of garlic, 15 18 parts of lily, 15 18 parts of corn stigma, 35 parts of radix glycyrrhizae.The present invention is advantageous in that：This product has effects that coronary artery dilator/arteriole, improves myocardial ischemia situation, adjusts blood pressure, with all worries set aside, qi and activate blood circulation of calming the nerves, anti-cerebral anoxia, antifatigue, strengthening by means of tonics, inducing diuresis for removing edema, to cardiovascular disease, especially coronary heart disease, chronic heart failure have good therapeutic effect, and instant effect, effect are notable, Small side effects.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, and in particular to a kind of Chinese medicine composition for treating cardiovascular disease, in belonging to
Medicine technical field.
Background technology
Coronary heart disease, chronic heart failure are most common disease of cardiovascular systems, and the cause of death is accounted in European and American developed countries
First place, account for the 3rd of the cause of death according to statistics in China, be only second to accident death and tumour, and morbidity has and increased year by year
Plus trend.The Chinese medicine preparation for the treatment of coronary heart disease and heart failure has immediate effect pills for curing heart disease, Diaoxinxue Kang, compound danshen dripping pills etc., west
Medicine has nitroglycerin, calcium antagonist (such as：Verapamil, isosorbide dinitrate), beta-blocker (such as：Inderal) etc..
Although these above-mentioned medicines all have preferable curative effect, in the market is for new efficient treatment coronary heart disease, the heart
The medicine declined remains vigorous demand.
The content of the invention
It is an object of the invention to provide one kind it is new, efficiently treat cardiovascular disease, especially coronary heart disease, chronic heart failure
The Chinese medicine composition exhausted.
In order to realize above-mentioned target, the present invention is adopted the following technical scheme that：
A kind of Chinese medicine composition for treating cardiovascular disease, it is characterised in that by weight, is made up of following raw material：
12-15 parts of rhodiola root, 12-15 parts of the red sage root, 5-8 parts of garlic, 15-18 parts of lily, 15-18 parts of corn stigma, radix glycyrrhizae 3-5
Part.
The Chinese medicine composition of foregoing treatment cardiovascular disease, it is characterised in that by weight, is made up of following raw material：
12 parts of rhodiola root, 12 parts of the red sage root, 8 parts of garlic, 16 parts of lily, 16 parts of corn stigma, 5 parts of radix glycyrrhizae；
Or, 12 parts of rhodiola root, 12 parts of the red sage root, 5 parts of garlic, 15 parts of lily, 15 parts of corn stigma, 5 parts of radix glycyrrhizae；
Or, 15 parts of rhodiola root, 15 parts of the red sage root, 8 parts of garlic, 18 parts of lily, 18 parts of corn stigma, 3 parts of radix glycyrrhizae.
The Chinese medicine composition of foregoing treatment cardiovascular disease, it is characterised in that preparation method is：
By the first alcohol extracting water extraction again of rhodiola root, the red sage root, garlic, lily, corn stigma and radix glycyrrhizae, with Aqueous extracts after alcohol extract concentration
Merge, oral liquid is made.
Effect of prescription is introduced with effect：
Rhodiola root：Qi and activate blood circulation, promotes blood circulation and relievings asthma can improve sleep, anti-cerebral anoxia, antifatigue, have to immunologic function and help
The effect just consolidated, strengthening by means of tonics, the effect to coronary heart disease, senile heart failure with auxiliary treatment.
The red sage root：Promoting blood circulation, cool blood detumescence, expansible coronary artery, improvement myocardial ischemia situation reduce blood pressure, calmed the nerves
It is with all worries set aside.
Garlic：The fat deposition in cardiovascular and cerebrovascular can be prevented, cholesterol is reduced, plasma concentration is reduced, increase arteriole
Expansion ratio, promotes vasodilation, adjusts blood pressure.
Lily：Have effects that to relieve inflammation or internal heat, moistening lung, calm the nerves, can treat that the heart is insufficiency of the spleen, dysphoria and insomnia disease caused by insufficiency of heart yin,
The people of eak after being ill is highly profitable.
Corn stigma：There is expel the heat-evil treating stranguria, soothing the liver cholagogic, inducing diuresis for removing edema, diuresis substantially, can increase chloride
Discharge rate, has preferable curative effect to oedema caused by a variety of causes.
Radix glycyrrhizae：Needle warming moxibustion, dispelling dampness and promoting diuresis, removing toxic substances, coordinating the drug actions of a prescription.
In side the red sage root and garlic be coronary artery dilator/arteriole, improve myocardial ischemia situation, adjust blood pressure, calm the nerves it is quiet
The panacea of the heart, is monarch, main to support life, takes long term usage more and does not hurt sb.'s feelings；Rhodiola root is qi and activate blood circulation, promotes blood circulation and relievings asthma, anti-cerebral anoxia, anti-tired
The superb work of labor, strengthening by means of tonics, lily be relieve inflammation or internal heat, moistening lung, strange agent of calming the nerves, be minister, master nourish one's nature, qi-restoratives of curing the disease；Corn stigma Li Shui disappears
It is swollen, radix glycyrrhizae dispelling dampness and promoting diuresis, removing toxic substances, coordinating the drug actions of a prescription；This Six-element compatibility, Xiang Jiye.
The present invention is advantageous in that：This product has coronary artery dilator/arteriole, improves myocardial ischemia situation, adjusts
Blood pressure, with all worries set aside, qi and activate blood circulation of calming the nerves, anti-cerebral anoxia, antifatigue, strengthening by means of tonics, effect of inducing diuresis for removing edema are saved, to cardiovascular disease,
Especially coronary heart disease, chronic heart failure have good therapeutic effect, and instant effect, effect are notable, Small side effects.
Embodiment
Make specific introduce to the present invention below in conjunction with specific embodiment.
First, prescription is prepared
The formula table of the prescription of table 1
| Formula 1 | Formula 2 | Formula 3 | |
| Rhodiola root | 12g | 12g | 15g |
| The red sage root | 12g | 12g | 15g |
| Garlic | 5g | 8g | 8g |
| Lily | 15g | 16g | 18g |
| Corn stigma | 15g | 16g | 18g |
| Radix glycyrrhizae | 5g | 5g | 3g |
2nd, oral liquid is made
Each raw material is weighed by formula, is then mixed, first alcohol extracting water extraction again is concentrated to alcohol extract, afterwards and Aqueous extracts
Merge, oral liquid is made.
3rd, usage and dosage
Above-mentioned oral liquid is the consumption of 3 days, oral per natural gift 3 times (early, middle and late).
15 days are a course for the treatment of, continuously take the 2-4 course for the treatment of.
4th, clinical observation
By WHO diagnostic criteria for coronary heart disease in 1976, we, which have selected 30 patients and take the Chinese medicine composition of the present invention, (controlled
Treatment group), 30 patients are have selected again takes isosorbide dinitrate (control group).
Treatment group：Man 17, female 13,51~77 years old age, the course of disease 1~10 year, wherein stable angina cordis 20, no
Stable angina cordis 10, complicated hypertension 5, diabetes 4.
Control group：Man 16, female 14,53~75 years old age, the course of disease 1~9 year, wherein stable angina cordis 22, no
Stable angina cordis 8, complicated hypertension 4, diabetes 4.
Test method：The Chinese medicine composition of the oral present invention for the treatment of group, per natural gift 3 times (early, middle and late)；Control group is oral
1 10mg of isosorbide dinitrate, 3 times a day.Two groups of courses for the treatment of are respectively 4 weeks.Hypertension, diabetic continue to take depressor and antidiabetic drug
Treatment.Hypertension, diabetic continue to take depressor and antidiabetic drug treatment.In before treatment, treatment during and treatment end
Afterwards, record angina pectoris attacks number of times, pain condition, number of times containing nitroglycerin, detection blood glucose, liver function, BUN and electrocardiogram, blood
Pressure, and record the adverse reaction after medication.
Curative effect determinate standard：
(1) angina pectoris symptom
It is effective：Angina pectoris disappears substantially, without nitroglycerin；
Effectively：Angina pectoris attacks number of times and nitroglycerin consumption halve；
It is invalid：Angina pectoris does not mitigate substantially or attack times are reduced less than half；
Aggravate：Angina pectoris attacks number of times and nitroglycerin consumption increase.
(2) electrocardiogram
It is effective：Tranquillization ischemic electrocardiographic recovers normal or substantially normal after treatment；
Effectively：S-T segment rise 0.05mv or so, T ripples, which are inverted, to be shoaled up to more than 50% or is switched to uprightly by flat；
It is invalid；S-T segment, the change of T ripples are without improvement；
Aggravate：S-T segment, the change of T ripples are aggravated.
Treatment results：
(1) treatment angina pectoris symptom total effective rate (effective added with effect)
Treatment group is 83.33%, and control group is 80%, and examining two groups of curative effect P values through X2, there was no significant difference.
(2) person's tranquillization ischemic electrocardiographic improves total effective rate (effective added with effect)
Treatment group is 60%, and control group is 56.67%, examines two groups of curative effect P ＞ 0.05 through X2, there was no significant difference.Two
Heart rate, liver function before and after group treatment, BUN are normal, on blood pressure, blood glucose without influence.Treatment group is during treating without any bad
Reaction occurs.
2 30 Treating Patients of Angina Pectoris symptoms and therapeutic effects of table
The tranquillization ischemic electrocardiographic efficacy analysis of table 3
As can be seen here, Chinese medicine composition of the invention has good to cardiovascular disease, especially coronary heart disease, chronic heart failure
Good therapeutic effect, instant effect, effect are notable.
It should be noted that the invention is not limited in any way for above-described embodiment, all use equivalent substitutions or equivalent change
The technical scheme that the mode changed is obtained, all falls within protection scope of the present invention.
Claims (5)
1. a kind of Chinese medicine composition for treating cardiovascular disease, it is characterised in that by weight, is made up of following raw material：
12-15 parts of rhodiola root, 12-15 parts of the red sage root, 5-8 parts of garlic, 15-18 parts of lily, 15-18 parts of corn stigma, 3-5 parts of radix glycyrrhizae.
2. it is according to claim 1 treatment cardiovascular disease Chinese medicine composition, it is characterised in that by weight, by with
Lower raw material composition：
12 parts of rhodiola root, 12 parts of the red sage root, 8 parts of garlic, 16 parts of lily, 16 parts of corn stigma, 5 parts of radix glycyrrhizae.
3. it is according to claim 1 treatment cardiovascular disease Chinese medicine composition, it is characterised in that by weight, by with
Lower raw material composition：
12 parts of rhodiola root, 12 parts of the red sage root, 5 parts of garlic, 15 parts of lily, 15 parts of corn stigma, 5 parts of radix glycyrrhizae.
4. it is according to claim 1 treatment cardiovascular disease Chinese medicine composition, it is characterised in that by weight, by with
Lower raw material composition：
15 parts of rhodiola root, 15 parts of the red sage root, 8 parts of garlic, 18 parts of lily, 18 parts of corn stigma, 3 parts of radix glycyrrhizae.
5. the Chinese medicine composition for the treatment of cardiovascular disease according to claim 1, it is characterised in that preparation method is：
By the first alcohol extracting water extraction again of rhodiola root, the red sage root, garlic, lily, corn stigma and radix glycyrrhizae, closed after alcohol extract concentration with Aqueous extracts
And, oral liquid is made.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710543426.5A CN107174639A (en) | 2017-07-05 | 2017-07-05 | Treat the Chinese medicine composition of cardiovascular disease |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710543426.5A CN107174639A (en) | 2017-07-05 | 2017-07-05 | Treat the Chinese medicine composition of cardiovascular disease |
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| Publication Number | Publication Date |
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| CN107174639A true CN107174639A (en) | 2017-09-19 |
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ID=59844661
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710543426.5A Pending CN107174639A (en) | 2017-07-05 | 2017-07-05 | Treat the Chinese medicine composition of cardiovascular disease |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060083798A1 (en) * | 2004-10-14 | 2006-04-20 | Jeffrey Young | Composition of natural herb extract for treating cardiovascular disease and its method of preparation thereof |
| CN1778337A (en) * | 2004-11-26 | 2006-05-31 | 天津天士力制药股份有限公司 | Preparation of compound Danshen Root tablet |
| CN101972353A (en) * | 2010-10-15 | 2011-02-16 | 彭军 | Medicine composition for preventing and treating heart cerebrovascular diseases |
-
2017
- 2017-07-05 CN CN201710543426.5A patent/CN107174639A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060083798A1 (en) * | 2004-10-14 | 2006-04-20 | Jeffrey Young | Composition of natural herb extract for treating cardiovascular disease and its method of preparation thereof |
| CN1778337A (en) * | 2004-11-26 | 2006-05-31 | 天津天士力制药股份有限公司 | Preparation of compound Danshen Root tablet |
| CN101972353A (en) * | 2010-10-15 | 2011-02-16 | 彭军 | Medicine composition for preventing and treating heart cerebrovascular diseases |
Non-Patent Citations (1)
| Title |
|---|
| 吴复苍等: "《常见病遣方用药规律》", 31 October 2015, 北京军医出版社 * |
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