CN1354003A - Medicine for curing angiocardiopathy and cerebrovascular disease and its preparing method - Google Patents

Medicine for curing angiocardiopathy and cerebrovascular disease and its preparing method Download PDF

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CN1354003A
CN1354003A CN 00132763 CN00132763A CN1354003A CN 1354003 A CN1354003 A CN 1354003A CN 00132763 CN00132763 CN 00132763 CN 00132763 A CN00132763 A CN 00132763A CN 1354003 A CN1354003 A CN 1354003A
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radix
grams
medicine
semen
cinnabaris
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CN1199659C (en
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王松彪
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Abstract

The Chinese patent medicine oral preparation for curing angiocardiopathy and cerebrovascular disease with the functions of obviously improving symptom and restoring normal function of heart is made up by using 20-odd Chinese medicinal materials of borneol, carthemus flower, cooked jujube kernel and water buffalo horn, etc. through a certain preparation process. Said invention does not produce drug dependence and does not produce recurrence. Said invention also discloses its preparation method

Description

A kind of medicine for the treatment of cardiovascular and cerebrovascular disease and preparation method thereof
The present invention relates to a kind of medicine for the treatment of cardiovascular and cerebrovascular disease and preparation method thereof
Cardiovascular and cerebrovascular disease is the higher a kind of disease of blood circulation sickness rate, and is in the majority with middle-older patient, and teenager also has morbidity by chance, and this sick its this asexuality and regional difference are brought endless misery to the patient, bring white elephant for family and society.At present, also do not have a kind of perfect medicine to treat this disease both at home and abroad, most medicines can only play to be alleviated and the effect of control, and exists the drawback that certain dependency and short-term drug withdrawal can be recurred.
The purpose of this invention is to provide a kind of medicine for the treatment of cardiovascular and cerebrovascular disease, take this medicine symptom is obviously improved and last complete obiteration, cardiac function can recover normally, to the medicine no dependence, is difficult for recurrence.
The present invention also provides the method for preparing above-mentioned this medicine.
Purpose of the present invention can be solved by following scheme; The treatment cardiovascular and cerebrovascular disease medicine, wherein be by following raw material by weight unit " gram " (except as otherwise herein provided) than making:
Rhizoma Chuanxiong 10~15 Flos Carthamis 10~15 Radix Paeoniae Rubra 8~12 Radix Angelicae Sinensis 12~18
Lignum Dalbergiae Odoriferae 10~15 Radix Salviae Miltiorrhizaes 8~18 ripe Semen Ziziphi Spinosae 10~15 Semen Platycladis 12~16
Radix Polygalae 12~16 Radix Et Rhizoma Rhei 8~12 Pericarpium Citri tangerinaes 10~15 Poria 12~15
Radix Curcumae 10~12 Spica Prunellaes 15~20 Cornu Bubalis 15~20 Os Draconis 20~25
Cinnabaris 7~12 succinums 7~12 Radix Glycyrrhizaes 10~15 Fructus Gardeniaes 5~10
Borneolum Syntheticum 2~4 Semen Cassiae seeds 6~10 Fructus Hordei Germinatus 20~25 Radixs Astragali 10~15
260~400 milliliters of the Radix Aucklandiae 10~15 Mel.
The method for preparing above-mentioned described medicine is:
At first to Rhizoma Chuanxiong, Flos Carthami, Radix Paeoniae Rubra, Radix Angelicae Sinensis, Lignum Dalbergiae Odoriferae, Radix Salviae Miltiorrhizae, ripe Semen Ziziphi Spinosae, Semen Platycladi, Radix Polygalae, Radix Et Rhizoma Rhei, Pericarpium Citri tangerinae, Poria, Radix Curcumae, Spica Prunellae, Cornu Bubali, Os Draconis, Cinnabaris, succinum, Radix Glycyrrhizae, the Fructus Gardeniae Borneolum Syntheticum, the Semen Cassiae seed, Fructus Hordei Germinatus, the Radix Astragali, the Radix Aucklandiae screens, and to removing Borneolum Syntheticum, succinum, the outer other medicines of Cinnabaris carry out rinsing, oven dry then, make water content less than 18%, be total to the porphyrize foam after again said medicine all being mixed and cross 140 mesh sieves, through sterilization steps, sterilization can be adopted 120 fens master slave modes of ultraviolet radiation, again the Mel heating is endured out 90~100 ℃, treat when the Mel temperature is reduced to 25~35 ℃ with sterilization after medicinal mixture fully mix stirring, make required dosage form at last.Can make 45~65 equal portions balls, heavily about 11~15 grams of every ball seal standby.
The present invention has these characteristics of ischemic according to cardiovascular and cerebrovascular disease more, at first adopted a large amount of can blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain again can coronary artery dilator, and the Rhizoma Chuanxiong, Flos Carthami, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Radix Et Rhizoma Rhei etc. that strengthen coronary artery blood flow are principal agent.Again in line with qi being the governor of blood, this theory of Chinese medical science that the capable then blood of gas is capable is equipped with awakening consciousness simultaneously, and medicines such as the Borneolum Syntheticum of regulating QI to relieve pain, the Radix Aucklandiae, Lignum Dalbergiae Odoriferae, Pericarpium Citri tangerinae, Radix Curcumae are to strengthen the dynamics of blood-activating and qi-promoting, blood stasis removing pain relieving.Because of the many symptoms of cardiovascular and cerebrovascular disease with headache, dizziness, insomnia, cerebral neurastheria such as forgetful, Cinnabaris, succinum, Os Draconis, Radix Polygalae, Semen Platycladi, ripe Semen Ziziphi Spinosae etc. have been reused in the prescription, tranquilizing mind, the medicine of mind calming Fructus Alpiniae Oxyphyllae, therefore the class medicine belongs to heart channel more, not only can improve the overall efficacy that perfect square centering is calmed the nerves again, also have the neck medicine and go into the heart, through sick effect.
In addition, the course of disease of cardiovascular and cerebrovascular disease is longer, and lead to prolong and do not heal, in long ill process, be easy to influence the function of spleen kidney, thereby anorexia appears, weak, breathe hard, the symptom of insufficiency of the spleen deficiency of the kidney such as hyperhidrosis, at this point, added Fructus Hordei Germinatus in the side, Radix Glycyrrhizae, Poria, the Radixs Astragali etc. play spleen invigorating, help digestion, during QI invigorating is transferred, the effect of kidney tonifying consolidating superficial resistance, because the course of disease time of primary disease is longer, most patients exist feelings intelligence benefit and become silted up, fever of the body is vexed, phenomenons such as yang hyperactivity constipation, thereby use Fructus Gardeniae again in the side, Cornu Bubali and Spica Prunellae Semen Cassiae seed are compatible, to reach clearing heart fire, shallow positive relieving constipation, liver heat removing and eyesight improving, adjust blood pressure, the purpose of cholesterol reducing.
Medicines such as the Radix Angelicae Sinensis in the side of having, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, the Radix Astragali, Poria, Radix Glycyrrhizae are compatible, except that having foregoing effect, the function of qi and blood tonifying, strengthening vital QI to eliminate pathogenic factors arranged also simultaneously.Many see full side, that invigorating middle warmer has is diffusing, can receive and can live, can feel relieved calm the nerves, promoting flow of QI and blood, but spleen invigorating is set upright again, the adjust blood pressure pathogenic fire reducing is to treat the optimal Chinese patent medicine for oral administration of cardiovascular and cerebrovascular disease.
Function: centering is calmed the nerves, vital energy regualting and blood circulation-promoting, spleen invigorating are set upright, the adjust blood pressure pathogenic fire reducing.
Cure mainly: angina pectoris, cardiac-cerebral ischemia, arrhythmia, atrial fibrillation premature beat, sensation of oppression over the chest with shortness of breath, nervous insomnia, dreaminess is forgetful, hyperhidrosis is weak, and symptoms such as anorexia constipation, unstable blood pressure.
Usage and consumption: early respectively take once before ante cibum, the supper every day, each 11~15 grams, and warm water delivery service, 25 days is a course of treatment.
Points for attention;
1, food such as peppery and wine of diet raw meat.
2, congenital heart disease and not being taken by pregnant women.
3, avoid environmental stimulis such as scaring, flu, anger as far as possible.
Provide embodiment and case below and describe curative effect of the present invention.
Embodiment 1
Form: Rhizoma Chuanxiong 12 grams, Flos Carthami 14 grams, Radix Paeoniae Rubra 10 grams, Lignum Dalbergiae Odoriferae 12 grams, Radix Salviae Miltiorrhizae 15 grams, ripe Semen Ziziphi Spinosae 12 grams, Semen Platycladi 15 grams, Radix Polygalae 15 grams, Radix Et Rhizoma Rhei 8 grams, Pericarpium Citri tangerinae 12 grams, Poria 12 grams, Radix Curcumae 10 grams, Spica Prunellae 18 grams, Cornu Bubali 18 grams, Os Draconis 25 grams, Cinnabaris 10 grams, succinum 12 grams, Radix Glycyrrhizae 10, Fructus Gardeniae 8 grams, Borneolum Syntheticum 3 grams, Semen Cassiae seed 8 grams, Fructus Hordei Germinatus 20 grams, Radix Angelicae Sinensis 15 grams, the Radix Astragali 15 grams, the Radix Aucklandiae 10 grams.
Preparation method: at first above-mentioned raw material is screened, other medicines carry out rinsing and dry then except that Borneolum Syntheticum, succinum, Cinnabaris, be total to the porphyrize foam at the mixture of will adding medicine to and cross 140 mesh sieves, through ultraviolet radiation after 120 minutes, again 350 milliliters of Mel are heated to 90~100 ℃ with the physical heating method, treat when the Mel temperature is reduced to 25~35 ℃ with sterilization after powder fully stir, make 55~60 equal portions balls, heavily about 11~12 grams of every ball.Seal standby.
Take for case 1 patient with the medicine that embodiment 1 makes.
Case 1
Name: the beautiful precious sex of punishment: woman's age: 55 years old
Identification card number: 222423450901498
Examine in June, 1994, readme 1989 is because after the overexcitement, and the sense pareordia has a dull ache, coloured silk behaviour and Electrocardioscopy through how tame hospital are diagnosed as coronary heart disease, angina pectoris, and with dreaminess, amnesia, the patient is always with medicine maintenance treatments such as propranolol, Radix Salviae Miltiorrhizae Tabellae, nitric acid liver oil sheets for many years, the i.e. outbreak repeatedly of symptom at this disease, is taken medicine of the present invention and is treated after the drug withdrawal.
Usage: use warm water delivery service 1 ball before early sleeping in ante cibum, evening every day.
Annotate: period in a medicine should be avoided environmental stimulis such as anger, scaring as far as possible, simultaneously the peppery food that waits of diet raw meat.
Using this medicine was a course of treatment in per 25 days.15 days state of an illness of medication begin to take a turn for the better, dreaminess after the course of treatment, symptom such as forgetful disappear substantially, and the angina pectoris attacks number of times also obviously reduces, and continue second course of treatment of medication, the equal complete obiteration of above-mentioned symptom, the patient can manage household affairs, for consolidating curative effect, has taken a course of treatment again, after the no abnormal change of Electrocardioscopy, followed up a case by regular visits to 5 years, and had after anger the slight sensation uncomfortable in chest, other symptom is not seen recurrence.
Embodiment 2
Form: Rhizoma Chuanxiong 15 grams, Flos Carthami 12 grams, Radix Paeoniae Rubra 10 grams, Lignum Dalbergiae Odoriferae 15 grams, Radix Salviae Miltiorrhizae 15 grams, ripe Semen Ziziphi Spinosae 10 grams, Semen Platycladi 15 grams, Radix Polygalae 12 grams, Radix Et Rhizoma Rhei 8 grams, Pericarpium Citri tangerinae 15 grams, Poria 15 grams, Radix Curcumae 10 grams, Spica Prunellae 20 grams, Cornu Bubali 15 grams, Os Draconis 20 grams, Cinnabaris 8 grams, succinum 12 grams, Radix Glycyrrhizae 10, Fructus Gardeniae 8 grams, Borneolum Syntheticum 3 grams, Semen Cassiae seed 10 grams, Fructus Hordei Germinatus 25 grams, Radix Angelicae Sinensis 15 grams, the Radix Astragali 15 grams, the Radix Aucklandiae 10 grams.
Preparation method is with embodiment 1.
Take for case 2 patients with the medicine that embodiment 2 makes.
Case 2
Name: Zhao Yunlong sex: man's age: 65 years old
Identification card number: 222403436360714251
Examine in November, 1997, readme 1985 is after excessive excessive drinking, and conscious have shapes such as nervous, uncomfortable in chest, hyperhidrosis, dizziness, anorexia, constipation, coloured silk behaviour through the Yan Bian the People's Hospital checks, be diagnosed as myocardial ischemia, and with cerebral arteriosclerosis, hypertension complication such as (115-175 millimetress of mercury).The patient takes medicine such as the long NAOXINTONG of blood pressure lowering stype always and keeps symptom for many years, need obey SUXIAO JIUXIN WAN when serious can alleviate, and over nearly 5 years, not only state of an illness improvement, the trend that increases the weight of day by day in addition.At this disease, take this medicine to the patient and treat.
Usage: use warm water delivery service 1 ball before early sleeping in ante cibum, evening every day.
Annotate; Period in a medicine should be avoided environmental stimulis such as anger, scaring as far as possible, simultaneously the peppery food that waits of diet raw meat.
Using this medicine was a course of treatment in per 25 days.After medication course of treatment, symptoms such as nervous, uncomfortable in chest, dizzy, constipation all have clear improvement, blood pressure also is stabilized in about the 90-145 millimetres of mercury, continues second course of treatment of medication, and nervous, uncomfortable in chest, hyperhidrosis, all stop using by complete obiteration depressor, SUXIAO JIUXIN WAN for weak symptom, the back is with the equal complete obiteration of medication all symptoms one course of treatment, appetite is showed increased also, can orthobiosis, after color behaviour checks, substantially, normal, follow up a case by regular visits to and do not see recurrence in 2 years.
Embodiment 3
Form: Rhizoma Chuanxiong 12 grams, Flos Carthami 12 grams, Radix Paeoniae Rubra 10 grams, Lignum Dalbergiae Odoriferae 12 grams, Radix Salviae Miltiorrhizae 15 grams, Semen Ziziphi Spinosae 12 grams, Semen Platycladi 15 grams, Radix Polygalae 15 grams, Radix Et Rhizoma Rhei 8 grams, Pericarpium Citri tangerinae 12 grams, Poria 12 grams, Radix Curcumae 10 grams, Spica Prunellae 18 grams, Cornu Bubali 18 grams, Os Draconis 25 grams, Cinnabaris 10 grams, succinum 12 grams, Radix Glycyrrhizae 10 grams, Fructus Gardeniae 8 grams, Borneolum Syntheticum 3 grams, Semen Cassiae seed 8 grams, Fructus Hordei Germinatus 20 grams, Radix Angelicae Sinensis 15 grams, the Radix Astragali 15 grams, the Radix Aucklandiae 10 gram.
Preparation method is with embodiment 1.
Take for case 3 patients with the medicine that embodiment 3 makes.
Case 3
Name: old eastern women is other: woman's age: 48 years old
Identification card number: 222423521112496
Patient's readme 1987 when a gallbladder resection operation, symptom such as because of scaring suffers from a heart complaint, that their early stage has only is uncomfortable in chest, breathe hard, insomnia.The patient does not add attention, through the time in about 1 year, the state of an illness begins to increase the weight of gradually, angina pectoris has appearred to nineteen ninety, heart stops, headache, condition of illness such as anorexia, the patient is cisco unity malfunction, checks through electrocardiogram and color behaviour, finds to have suffered from serious coronary atherosclerosis, phenomenons such as arrhythmia, take DIAOXINXUE KANG, heart treasured and vitamin medicaments treatment, symptom does not all have obvious improvement, and since nineteen ninety-five, the angina pectoris number of times reaches more than 3 times every day, and attack times is frequent gradually, behind angry or scaring, dizzy fan is also taken place sometimes, serious symptoms such as shock, the patient need obey 3-5 SUXIAO JIUXIN WAN every day and come mitigate the disease, can not orthobiosis, when examined in July, 1998, the patient need assist walking in, rhythm of the heart per minute about 100 times, blood pressure is on the low side (50-80 millimetres of mercury), and with anorexia, symptoms such as constipation.At this disease, take medicine of the present invention to the patient and treat.
Usage: use warm water delivery service 1 ball before early sleeping in ante cibum, evening every day.
Annotate: period in a medicine should be avoided environmental stimulis such as anger, scaring as far as possible, simultaneously the peppery food that waits of diet raw meat.
Using this medicine was a course of treatment in per 25 days.After medication course of treatment, phenomenon such as uncomfortable in chest, as to breathe hard begins to take a turn for the better, anginal attack times also obviously reduces, the patient only need obey pills for curing heart disease once in a while to be alleviated, continue second course of treatment of medication, blood pressure is also near normal level (80-120 millimetres of mercury), and the rhythm of the heart is also reduced to per minute about 80 times, and SUXIAO JIUXIN WAN can be withdrawn fully.Continue the 3rd course of treatment of medication, the equal complete obiterations of symptom such as all stupors, shock, but patient's operate as normal and life are taken medicine again and were promptly discontinued medication in 15 days for consolidating curative effect, follow up a case by regular visits to and do not see recurrence in 2 years.

Claims (2)

1, a kind of medicine for the treatment of cardiovascular and cerebrovascular disease, wherein be by following raw material by weight unit " gram " (except as otherwise herein provided) than making:
Rhizoma Chuanxiong 10~15 Flos Carthamis 10~15 Radix Paeoniae Rubra 8~12 Radix Angelicae Sinensis 12~18
Lignum Dalbergiae Odoriferae 10~15 Radix Salviae Miltiorrhizaes 8~18 ripe Semen Ziziphi Spinosae 10~15 Semen Platycladis 12~16
Radix Polygalae 12~16 Radix Et Rhizoma Rhei 8~12 Pericarpium Citri tangerinaes 10~15 Poria 12~15
Radix Curcumae 10~12 Spica Prunellaes 15~20 Cornu Bubalis 15~20 Os Draconis 20~25
Cinnabaris 7~12 succinums 7~12 Radix Glycyrrhizaes 10~15 Fructus Gardeniaes 5~10
Borneolum Syntheticum 2~4 Semen Cassiae seeds 6~10 Fructus Hordei Germinatus 20~25 Radixs Astragali 10~15
260~400 milliliters of the Radix Aucklandiae 10~15 Mel.
2, prepare the method for the described medicine of claim 1, it is characterized in that:
At first Rhizoma Chuanxiong, Flos Carthami, Radix Paeoniae Rubra, Radix Angelicae Sinensis, Lignum Dalbergiae Odoriferae, Radix Salviae Miltiorrhizae, ripe Semen Ziziphi Spinosae, Semen Platycladi, Radix Polygalae, Radix Et Rhizoma Rhei, Pericarpium Citri tangerinae, Poria, Radix Curcumae, Spica Prunellae, Cornu Bubali, Os Draconis, Cinnabaris, succinum, Radix Glycyrrhizae, Fructus Gardeniae, Borneolum Syntheticum, Semen Cassiae seed, Fructus Hordei Germinatus, the Radix Astragali, the Radix Aucklandiae are screened, and other medicines except that Borneolum Syntheticum, succinum, Cinnabaris are carried out rinsing, oven dry then.Again said medicine is all mixed the back altogether the porphyrize foam cross 140 mesh sieves, behind sterilization process, again the Mel heating is endured out 90~100 ℃, treat when the Mel temperature is reduced to 25~35 ℃ with sterilize after medicinal mixture fully mix stirring, make required dosage form at last.
CN 00132763 2000-11-17 2000-11-17 Medicine for curing angiocardiopathy and cerebrovascular disease and its preparing method Expired - Fee Related CN1199659C (en)

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100509009C (en) * 2005-04-25 2009-07-08 云南生物谷灯盏花药业有限公司 A traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases and ischemic stroke and its preparation method
CN100509010C (en) * 2005-04-25 2009-07-08 云南生物谷灯盏花药业有限公司 A traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases and its preparation method
CN1931260B (en) * 2006-09-23 2010-09-08 孟平安 Hyperlipemia treating oral liquid
CN102614460A (en) * 2012-03-31 2012-08-01 陈欣 Traditional Chinese medicine composition for treating myocardial infarction and preparation method thereof
CN103142941A (en) * 2012-03-31 2013-06-12 陈欣 Traditional Chinese medicine composition capsule for treating myocardial infarction and preparation method thereof
CN103142942A (en) * 2012-03-31 2013-06-12 陈欣 Traditional Chinese medicine composition tablet for treating myocardial infarction and preparation method thereof
CN105232646A (en) * 2015-11-16 2016-01-13 杨全江 Traditional Chinese medicine acupuncture point external medicine bag for treating cardiovascular and cerebrovascular diseases and preparation method thereof
CN105250657A (en) * 2015-11-12 2016-01-20 济南大学 Medicine composition for treating atherosclerosis and preparation method thereof
CN111184841A (en) * 2019-08-12 2020-05-22 郭春海 Medicine for treating cardiovascular and cerebrovascular diseases and preparation method thereof

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100509009C (en) * 2005-04-25 2009-07-08 云南生物谷灯盏花药业有限公司 A traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases and ischemic stroke and its preparation method
CN100509010C (en) * 2005-04-25 2009-07-08 云南生物谷灯盏花药业有限公司 A traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases and its preparation method
CN1931260B (en) * 2006-09-23 2010-09-08 孟平安 Hyperlipemia treating oral liquid
CN102614460B (en) * 2012-03-31 2013-10-30 陈欣 Traditional Chinese medicine composition for treating myocardial infarction and preparation method thereof
CN103142941A (en) * 2012-03-31 2013-06-12 陈欣 Traditional Chinese medicine composition capsule for treating myocardial infarction and preparation method thereof
CN103142942A (en) * 2012-03-31 2013-06-12 陈欣 Traditional Chinese medicine composition tablet for treating myocardial infarction and preparation method thereof
CN102614460A (en) * 2012-03-31 2012-08-01 陈欣 Traditional Chinese medicine composition for treating myocardial infarction and preparation method thereof
CN103142942B (en) * 2012-03-31 2014-07-02 孔庆来 Traditional Chinese medicine composition tablet for treating myocardial infarction and preparation method thereof
CN103142941B (en) * 2012-03-31 2014-07-23 陈欣 Traditional Chinese medicine composition capsule for treating myocardial infarction and preparation method thereof
CN105250657A (en) * 2015-11-12 2016-01-20 济南大学 Medicine composition for treating atherosclerosis and preparation method thereof
CN105232646A (en) * 2015-11-16 2016-01-13 杨全江 Traditional Chinese medicine acupuncture point external medicine bag for treating cardiovascular and cerebrovascular diseases and preparation method thereof
CN105232646B (en) * 2015-11-16 2019-02-26 杨全江 A kind of traditional Chinese medicine acupoint external application pack that treating cardiovascular and cerebrovascular disease and preparation method
CN111184841A (en) * 2019-08-12 2020-05-22 郭春海 Medicine for treating cardiovascular and cerebrovascular diseases and preparation method thereof

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