CN105535553A - Formula for regulating blood sugar of human body - Google Patents

Formula for regulating blood sugar of human body Download PDF

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Publication number
CN105535553A
CN105535553A CN201610135980.5A CN201610135980A CN105535553A CN 105535553 A CN105535553 A CN 105535553A CN 201610135980 A CN201610135980 A CN 201610135980A CN 105535553 A CN105535553 A CN 105535553A
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China
Prior art keywords
formula
blood sugar
human body
regulate
weight
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CN201610135980.5A
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Chinese (zh)
Inventor
卢志斌
沈秋阳
林文亮
卢绍基
潘大仁
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XIAMEN TASMAN BIO-TECH Co Ltd
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XIAMEN TASMAN BIO-TECH Co Ltd
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Priority to CN201610135980.5A priority Critical patent/CN105535553A/en
Publication of CN105535553A publication Critical patent/CN105535553A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8984Dendrobium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/52Juglandaceae (Walnut family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention discloses a formula for regulating blood sugar of a human body. The formula is prepared from 20%-40% by weight of dendrobium officinale, 5%-15% by weight of American ginseng powder, 5%-15% by weight of radix notoginseng powder, 5%-15% by weight of fructus lycii, 10%-30% by weight of pueraria starch, 5%-15% by weight of moringa seeds and 5%-15% by weight of cyclocarya paliurus. Lozenges and capsules can be prepared according to the formula. According to the formula, treatment is performed aiming at different paths causing hyperglycemia through interaction of the raw materials, the blood sugar value is reduced, and a blood pressure reduction effect is enhanced.

Description

A kind of formula regulating blood sugar for human body
Technical field
The present invention relates to Chinese medicine health-care field, particularly relate to a kind of formula regulating blood sugar for human body.
Background technology
Current people are fast playing under the life with high pressure, physical condition declines day by day, in recent years, the M & M of the major diseases such as China's malignant tumor, diabetes is just presenting and is continuing to rise and rejuvenation trend, becomes the key factor threatening people's life health.Correlation report show, China's diabetes prevalence also from 0.67% in 1980 soar to 2008 within 9.7%, 2013, then rise to 11.6%.When not getting enough athletic exercise, how the adjustment human body blood sugar level of science, becomes the problem that people are concerned about.
Summary of the invention
The object of the present invention is to provide a kind of for regulating the formula of blood sugar for human body.
For achieving the above object, the invention provides a kind of formula regulating blood sugar for human body, it is characterized in that, prepared by each composition of following percentage by weight,
Herba Dendrobii 20-40%;
Amylum Puerariae Radicis 10-30%;
Radix Panacis Quinquefolii 5-15%;
Radix Notoginseng 5-15%;
Fructus Lycii 5-15%;
Moringa seeds 5-15%;
Money willow 5-15%.
Further, prepared by each composition of following percentage by weight,
Herba Dendrobii 30-40%;
Amylum Puerariae Radicis 20-30%;
Radix Panacis Quinquefolii 5-10%;
Radix Notoginseng 5-10%;
Fructus Lycii 5-15%;
Moringa seeds 5-10%;
Money willow 5-10%.
Further, prepared by each composition of following percentage by weight,
Herba Dendrobii 30%;
Amylum Puerariae Radicis 20%;
The West Ginseng 10%;
Radix Notoginseng 10%;
Fructus Lycii 10%;
Moringa seeds 10%;
Money willow 10%.
Further, described each composition is 80-100 object powder.
The formula of adjustment blood sugar for human body of the present invention, can be prepared into buccal tablet or capsule.
The present invention also provides the purposes of formula for reducing blood sugar in diabetic patients of described adjustment blood sugar for human body.
The present invention also provides the formula of described adjustment blood sugar for human body for strengthening the purposes of diabetics body constitution.
The present invention also provides the formula of described adjustment blood sugar for human body smooth and easy for making diabetics breathe, the purposes that diarrhoea constipation symptom disappears.
The purposes that the present invention also provides the formula of described adjustment blood sugar for human body to be clearly better for making diabetic complication nephrotic renal function;
Optional, for making diabetic complication hyperpietic blood pressure obviously decline, the purposes that health status takes a turn for the better;
Optional, for making diabetic complication cardiovascular and cerebrovascular disease patients symptomatic significantly alleviate, the purposes that health status takes a turn for the better.
Herba Dendrobii of the present invention has the function that replenishing YIN and removing heat is moisturized, and is exactly the medicine dedicated for the treatment of diabetes since ancient times.Clinical research shows, Herba Dendrobii not only can strengthen insulin active, significantly can reduce blood sugar level simultaneously, make blood normal; Circulation, blood vessel dilating, reduction cholesterolemia and triglyceride can be promoted.When the Herba Dendrobii content in formula of the present invention exceedes protection domain, during the consumption of Herba Dendrobii more than 40%, convulsions can be caused.Lower than the amount of 20%, then can not play the effect reducing blood sugar level, reduce cholesterolemia and triglyceride very well.
Radix Panacis Quinquefolii of the present invention can reduce blood glucose, regulates insulin secretion, promote carbohydrate metabolism and lipid metabolism, has certain assosting effect to treatment diabetes.When the Radix Panacis Quinquefolii content in formula of the present invention exceedes protection domain, when the consumption of Radix Panacis Quinquefolii is more than 15, the symptoms such as mood excited, irritated worry, insomnia, headache can be brought to people; When weight lower than 5%, well can not play and reduce blood glucose, regulate insulin secretion, promote carbohydrate metabolism and lipometabolic effect.
Radix Notoginseng of the present invention has dissipating blood stasis hemostasis, effect of subduing swelling and relieving pain.When the Radix Notoginseng content in formula of the present invention exceedes protection domain, when the consumption of Radix Notoginseng is more than 15%, easily thirsty, there is excitation; When weight lower than 5%, dissipating blood stasis hemostasis well can not be played, effect of subduing swelling and relieving pain.
Fructus Lycii of the present invention can prevent and treat diabetes.When the Fructus Lycii content in formula of the present invention exceedes protection domain, when the consumption of Fructus Lycii is more than 15%, eyes can be caused red swollen uncomfortable, the side effect such as blurred vision; When weight lower than 5%, can not well and other compositions mutually work in coordination with, for preventing and treating diabetes.
Amylum Puerariae Radicis of the present invention, containing trace element and the several amino acids such as zinc, ferrum, calcium, vitamin B1, B2 of needed by human, is the wholefood that nutritive value is very high.There is blood fat reducing function.When the Amylum Puerariae Radicis content in formula of the present invention exceedes protection domain, when the consumption of Amylum Puerariae Radicis is more than 30%, schoolgirl's menoxenia can be caused, long speckle; When consumption lower than 10% time, can not with other compositions work in coordination with, better reduce blood fat.
Moringa seeds of the present invention contains abundant nutritional labeling.At reduction blood fat, blood pressure, weight-reducing, regulates the intestines and stomach, hepatoprotective alleviating alcohol addiction, strengthens body immunity aspect and has significant curative effect.When the moringa seeds content in formula of the present invention exceedes protection domain, when the consumption of moringa seeds is more than 15%, hepatic disfunction can be caused; When consumption lower than 5% time, can not with other compositions work in coordination with, better reduce blood fat.
Money willow of the present invention can control the cardiovascular and cerebrovascular disease such as arteriosclerosis, diabetes, has good curative effect.Each composition of the present invention is 80-100 object powder.
Buccal tablet:
Pulverize: Herba Dendrobii, Radix Panacis Quinquefolii, Radix Notoginseng, Fructus Lycii, Radix Puerariae, moringa seeds, money willow are crushed to 80-100 order respectively;
Mixing: get dendrobium officinale powder by weight, Radix Panacis Quinquefolii powder, Radix Notoginseng powder, Fructus Lycii powder, powder of Radix Puerariae, moringa seeds powder, money willow powder add trough-type mixture machine mixing 30-50min.
Soft material processed: powder adds appropriate wetting agent ethanol and makes soft material after mixing, and its humidity is agglomerating with what hold, that touches is namely loosely as the criterion;
Granulate: the soft material that will make is put comminutor and made wet granular;
Dry: wet granular to be put baking oven and carry out drying, require baking temperature 70 ~ 80 DEG C, 3 hours time, make material moisture≤1.5%;
Granulate: dried material carries out granulate, requires uniform particles;
Tabletting: granule is placed in rotary tablet machine and carries out tabletting.0.5g/ sheet
Sterilizing, packaging.
Capsule:
Pulverize: Herba Dendrobii, Radix Panacis Quinquefolii, Radix Notoginseng, Fructus Lycii, Radix Puerariae, moringa seeds, money willow are crushed to 80-100 order respectively;
Mixing: get dendrobium officinale powder by weight, Radix Panacis Quinquefolii powder, Radix Notoginseng powder, Fructus Lycii powder, powder of Radix Puerariae, moringa seeds powder, money willow powder add trough-type mixture machine mixing 30-50min.
Fill 0.4g/ grain, sterilizing, packaging.
Regulate the formula gained capsule of blood sugar for human body according to the present invention, after taking 20 days (one day three times, each four) to 20 diabetes muscle power and the obvious person of weight loss symptom, body constitution strengthens, and health status is clearly better.
Regulate the formula gained capsule of blood sugar for human body according to the present invention, take 20 days (one day three times, each four) to 20 diabetes palpitation and short breaths, the obvious person of diarrhoea constipation symptom, breathe smooth and easy, diarrhoea constipation symptom disappears, and health status takes a turn for the better.
Regulate the formula gained buccal tablet of blood sugar for human body according to the present invention, after taking 20 days (one day three times, each four) to 20 diabetic complication nephrotics, renal function is clearly better.
Regulate the formula gained buccal tablet of blood sugar for human body according to the present invention, after taking 20 days (one day three times, each four) to 20 diabetic complication hyperpietics, blood pressure obviously declines, and health status takes a turn for the better.
Regulate the formula gained buccal tablet of blood sugar for human body according to the present invention, after taking 20 days (one day three times, each four) to 20 diabetic complication cardiovascular and cerebrovascular vessel patients, symptom significantly alleviates, and health status takes a turn for the better.
Detailed description of the invention
Be described below in detail embodiments of the invention, the example of described embodiment is intended to for explaining the present invention, and can not be interpreted as limitation of the present invention.Unreceipted concrete technology or condition person in embodiment, according to the technology described by the document in this area or condition or carry out according to product description.Agents useful for same or the unreceipted production firm person of instrument, being can by the conventional products of commercial acquisition.
Embodiment 1: the preparation regulating the formula of blood sugar for human body
Raw material is in table 1;
The raw materials used table of each embodiment of table 1 (percentage by weight)
Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4
Herba Dendrobii 20 30 40 35
Powder of Radix Puerariae 30 20 10 25
The West Ginseng powder 15 10 8 5
Radix Notoginseng powder 15 10 7 5
Fructus Lycii 10 10 5 15
Moringa seeds 5 10 15 9
Money willow 5 10 15 6
Preparation method:
Buccal tablet:
Pulverize: Herba Dendrobii, Radix Panacis Quinquefolii, Radix Notoginseng, Fructus Lycii, Radix Puerariae, moringa seeds, money willow are crushed to 80-100 order respectively;
Mixing: get dendrobium officinale powder by weight, Radix Panacis Quinquefolii powder, Radix Notoginseng powder, Fructus Lycii powder, powder of Radix Puerariae, moringa seeds powder, money willow powder add trough-type mixture machine mixing 30-50min.
Soft material processed: powder adds appropriate wetting agent ethanol and makes soft material after mixing, and its humidity is agglomerating with what hold, that touches is namely loosely as the criterion;
Granulate: the soft material that will make is put comminutor and made wet granular;
Dry: wet granular to be put baking oven and carry out drying, require baking temperature 70 ~ 80 DEG C, 3 hours time, make material moisture≤1.5%;
Granulate: dried material carries out granulate, requires uniform particles;
Tabletting: granule is placed in rotary tablet machine and carries out tabletting.0.5g/ sheet
Sterilizing, packaging.
Capsule:
Pulverize: Herba Dendrobii, Radix Panacis Quinquefolii, Radix Notoginseng, Fructus Lycii, Radix Puerariae, moringa seeds, money willow are crushed to 80-100 order respectively;
Mixing: get dendrobium officinale powder by weight, Radix Panacis Quinquefolii powder, Radix Notoginseng powder, Fructus Lycii powder, powder of Radix Puerariae, moringa seeds powder, money willow powder add trough-type mixture machine mixing 30-50min.
Fill 0.4g/ grain, sterilizing, packaging.
Embodiment 2:
Raw material is in table 1;
Preparation method is with embodiment 1.
Embodiment 3:
Raw material is in table 1;
Preparation method is with embodiment 1.
Embodiment 4:
Raw material is in table 1;
Preparation method is with embodiment 1.
Embodiment 5: animal demonstration test
Streptozotocin, Sigma Products; Glucose estimation kit, Sen Beijia bio tech ltd, Nanjing; Ultraviolet-uisible spectrophotometer, Shanghai spectral element Instrument Ltd.; Electronic weighing balance, Shanghai Hengping Science Instrument Co., Ltd..
Laboratory animal: Kunming mouse (20 ± 2g), experiment before natural lighting, freely drink water, routine raising.The administration of mice fasting 18-24h, streptozotocin 50mg/Kg tail vein injection, observe after typical " three-many-one-little " (polydipsia, polyphagia, polyuria, lose weight) diabetic symptom appears in mice, blood is got in docking.Measure mice fasting blood sugar with glucose oxidase-peroxidase terminal colorimetric analysis, get the selected experiment of blood glucose value >=10.0mmol/L.
The mice being defined as diabetes is divided into 12 groups at random, often organizes 10; Each group of all conventional raising, natural lighting, freely drinks water.Each group of processing mode sees the following form 2.
Continuous process 4 weeks, docking gets blood, with determination of glucose oxidase mice fasting blood sugar.With the blood glucose value of gavage normal saline for matched group, compare officinal Dendrobium stem capsule that officinal Dendrobium stem capsule raw material and different proportion make to the blood sugar decreasing effect of diabetic mice.Result is also in table 2.
Table 2 respectively organizes processing mode and the result of the test table of mice
From table 2 result, matched group average blood sugar value reaches 14.69mmol/L, presents the typical hyperglycemic symptoms of diabetes.The average blood sugar value of group 1-group 7 (Herba Dendrobii powder, Radix Puerariae powder, American Ginseng powder, Notoginseng Root, Fructus Lycii powder, moringa seeds powder, money willow powder) is respectively 7.73,10.25,12.02,9.28,9.84,8.15,8.58; The average blood sugar value of group 8-11 (embodiment 1 gained, embodiment 2 gained, embodiment 3 gained, embodiment 4 gained) is respectively: 5.50,4.80,6.88,5.72mmol/L.Experimental data is had to obtain, though independent raw material has hypoglycemic effect, but DeGrain.Ratio is too high or too low all can lower its effect.It causes the path of hyperglycemia to carry out treating the effect that reduction blood glucose value reaches its blood pressure lowering of enhancing by raw-material interaction for difference.
Although illustrate and describe embodiments of the invention above, be understandable that, above-described embodiment is exemplary, can not be interpreted as limitation of the present invention, those of ordinary skill in the art can change above-described embodiment within the scope of the invention when not departing from principle of the present invention and aim, revising, replacing and modification.

Claims (9)

1. regulate a formula for blood sugar for human body, it is characterized in that, prepared by each composition of following percentage by weight,
Herba Dendrobii 20-40%;
Amylum Puerariae Radicis 10-30%;
Radix Panacis Quinquefolii 5-15%;
Radix Notoginseng 5-15%;
Fructus Lycii 5-15%;
Moringa seeds 5-15%;
Money willow 5-15%.
2. regulate the formula of blood sugar for human body according to claim 1, it is characterized in that, prepared by each composition of following percentage by weight,
Herba Dendrobii 30-40%;
Amylum Puerariae Radicis 20-30%;
Radix Panacis Quinquefolii 5-10%;
Radix Notoginseng 5-10%;
Fructus Lycii 5-15%;
Moringa seeds 5-10%;
Money willow 5-10%.
3. regulate the formula of blood sugar for human body according to claim 1, it is characterized in that, prepared by each composition of following percentage by weight,
Herba Dendrobii 30%;
Amylum Puerariae Radicis 20%;
The West Ginseng 10%;
Radix Notoginseng 10%;
Fructus Lycii 10%;
Moringa seeds 10%;
Money willow 10%.
4. regulate the formula of blood sugar for human body described in any one of claim 1-3, it is characterized in that, described each composition is 80-100 object powder.
5. regulate the formula of blood sugar for human body described in any one of claim 1-3, it is characterized in that, be prepared into buccal tablet or capsule.
6. described in any one of claim 1-3, regulate the purposes of formula for reducing blood sugar in diabetic patients of blood sugar for human body.
7. described in any one of claim 1-3, regulate the formula of blood sugar for human body for strengthening the purposes of diabetics body constitution.
8. regulate the formula of blood sugar for human body to be used for that diabetics is breathed described in any one of claim 1-3 smooth and easy, the purposes that diarrhoea constipation symptom disappears.
9. described in any one of claim 1-3, regulate the purposes that the formula of blood sugar for human body is clearly better for making diabetic complication nephrotic renal function;
Optional, for making diabetic complication hyperpietic blood pressure obviously decline, the purposes that health status takes a turn for the better;
Optional, for making diabetic complication cardiovascular and cerebrovascular disease patients symptomatic significantly alleviate, the purposes that health status takes a turn for the better.
CN201610135980.5A 2016-03-10 2016-03-10 Formula for regulating blood sugar of human body Pending CN105535553A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107648596A (en) * 2017-10-26 2018-02-02 叶宁 A kind of fruit stem cell drugs and preparation method thereof
CN113142572A (en) * 2021-05-12 2021-07-23 李国峰 Fruit and vegetable type nutritious food and preparation method thereof

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107648596A (en) * 2017-10-26 2018-02-02 叶宁 A kind of fruit stem cell drugs and preparation method thereof
CN113142572A (en) * 2021-05-12 2021-07-23 李国峰 Fruit and vegetable type nutritious food and preparation method thereof

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Application publication date: 20160504