CN107158297B - 一种治疗骨科疼痛的中药膏及其制备方法 - Google Patents
一种治疗骨科疼痛的中药膏及其制备方法 Download PDFInfo
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Abstract
本发明涉及治疗骨科疼痛的中药膏及其制备方法,可有效解决骨科疼痛的用药问题,解决的技术方案是,该中药膏是由以下重量份数计的原料制成:麻黄15‑25份、羌活25‑35份、白芷25‑35份、防风25‑35份、威灵仙25‑35份、木瓜25‑35份、寻骨风25‑35份、海风藤25‑35份、虎杖25‑35份、山柰15‑25份、独活15‑25份、当归15‑25份、川牛膝15‑25份、杜仲25‑35份、续断25‑35份、生川乌25‑35份、生草乌25‑35份、天南星15‑25份、马钱子25‑35份、三七15‑25份、血竭15‑25份、蜈蚣10‑20份、全蝎10‑20份、猪牙皂25‑35份、丁香25‑35份、花椒25‑35份、乳香20‑35份、没药20‑35份、土鳖虫25‑35份、冰片25‑35份、医用压敏胶80‑120份、氮酮4‑6份,本发明原料易得,原料配比科学合理,制备方法简单,且能达到标本兼治的效果,是治疗骨科疼痛药物上的创新。
Description
技术领域
本发明涉及医药领域,特别是一种治疗骨科疼痛的中药膏及其制备方法。
背景技术
近年来,在临床中颈腰椎病、肩周炎、骨性关节病、风湿性关节病、滑膜炎、足跟痛、跌打损伤及骨折等骨科疼痛疾病发病率逐年上升,尤其是颈肩腰腿疼疾病向年轻化发展。目前对该类疾病治疗方法多元化,以药物镇痛、物理治疗、传统理疗以及中医中药的治疗为主。而中医中药的治疗标本兼治,无毒副作用,深受广大患者的接受。基于对治疗效果的追求,发明一种疗效更好,更确切,治愈率高的中药势在必行。
发明内容
针对上述情况,为解决现有技术之缺陷,本发明之目的就是提供一种治疗骨科疼痛的中药膏及其制备方法,可有效解决骨科疼痛的用药问题。
本发明解决的技术方案是,该中药膏是由以下重量份数计的原料制成:麻黄15-25份、羌活25-35份、白芷25-35份、防风25-35份、威灵仙25-35份、木瓜25-35份、寻骨风25-35份、海风藤25-35份、虎杖25-35份、山柰15-25份、独活15-25份、当归15-25份、川牛膝15-25份、杜仲25-35份、续断25-35份、生川乌25-35份、生草乌25-35份、天南星15-25份、马钱子25-35份、三七15-25份、血竭15-25份、蜈蚣10-20份、全蝎10-20份、猪牙皂25-35份、丁香25-35份、花椒25-35份、乳香20-35份、没药20-35份、土鳖虫25-35份、冰片25-35份、医用压敏胶80-120份、氮酮4-6份。
中药膏制备方法如下:
首先将麻黄、羌活、白芷、防风、威灵仙、木瓜、寻骨风、海风藤、虎杖、山柰、独活、当归、川牛膝、杜仲、续断、生川乌、生草乌、天南星、马钱子粉碎成细末,加等量灭菌用水,浓缩至原重量的80%,制成水煮浸膏,备用;再将三七、血竭、蜈蚣、全蝎、猪牙皂、丁香、花椒、乳香、没药、土鳖虫、冰片粉碎成细末,加入等量体积浓度为95%的医用酒精,浸泡1周,制成乙醇浸膏,备用;最后将水煮浸膏:乙醇浸膏按原料药重量比为2:1混合,加热干燥成混合药粉,将医用压敏胶加热融化,加入混合药粉,再加入氮酮,比例为医用压敏胶:混合药粉:氮酮=20:15:1,搅拌均匀成膏,在医用膏药空白贴布上摊制成型,即得。
本发明选料讲究,原料易得,原料配比科学合理,制备方法简单,对于颈腰椎病、肩周炎、骨性关节病、风湿性关节病、滑膜炎、足跟痛、跌打损伤及骨折等骨科疼痛疾病的治疗效果好,无任何毒作用,并且能达到标本兼治的效果,是治疗骨科疼痛药物上的创新。
具体实施方式
以下结合实施例对本发明的具体实施方式作进一步详细说明。
实施例1
本发明在具体实施时,可由以下重量份数计的原料制成:麻黄16份、羌活34份、白芷26份、防风34份、威灵仙26份、木瓜34份、寻骨风26份、海风藤34份、虎杖26份、山柰24份、独活16份、当归24份、川牛膝16份、杜仲34份、续断26份、生川乌34份、生草乌26份、天南星24份、马钱子26份、三七24份、血竭16份、蜈蚣19份、全蝎11份、猪牙皂34份、丁香26份、花椒34份、乳香21份、没药34份、土鳖虫26份、冰片34份、医用压敏胶120份、氮酮6份。
实施例2
本发明在具体实施时,还可由以下重量份数计的原料制成:麻黄20份、羌活30份、白芷30份、防风30份、威灵仙30份、木瓜30份、寻骨风30份、海风藤30份、虎杖30份、山柰20份、独活20份、当归20份、川牛膝20份、杜仲30份、续断30份、生川乌30份、生草乌30份、天南星20份、马钱子30份、三七20份、血竭20份、蜈蚣15份、全蝎15份、猪牙皂30份、丁香30份、花椒30份、乳香25份、没药25份、土鳖虫30份、冰片30份、医用压敏胶100份、氮酮5份。
本发明组分中:
麻黄:发汗解表,宣肺平喘,利水消肿,兼有散寒通滞作用,用治风寒痹症。
羌活:散寒祛风,胜湿止痛。用于风寒湿痹,肩臂疼痛。
白芷:解表散风,通窍,止痛,燥湿止带,消肿排脓。可用于风寒湿痹,腰背疼痛。
防风:发表散风,胜湿止痛,止痉,止泻。用于风寒湿痹,肢节疼痛,筋脉挛急。
威灵仙:祛风湿,通经络,消骨鲠。用于风湿痹痛,为风湿痹痛要药。
木瓜:舒筋活络,除湿和胃。用于风湿痹痛,筋脉拘挛,脚气肿痛。为久风顽痹筋脉拘急之要药。
寻骨风:祛风湿,通络止痛。用于风湿痹痛,肢体麻木,及跌打损伤。
海风藤:祛风除湿,通经活络。用于风湿痹痛,关节不利,筋脉拘挛,及跌打损伤疼痛。
独活:祛风湿,止痹痛,解表。用于风寒湿痹痛。
虎杖:利胆退黄,清热解毒。活血祛瘀,祛痰止咳。可用于血瘀经闭,跌打损伤。
山柰:温中化湿,行气止痛。可用于胸腹冷痛,跌打损伤,
当归:补血,活血,调经,止痛,润肠。用于血虚血滞兼有寒凝,以及跌打损伤,风湿痹阻的疼痛证。
川牛膝:活血通经,补肝肾,强筋骨,利水通淋,引火下行。用于治疗跌打损伤,腰膝瘀痛等
杜仲:补肝肾,强筋骨,安胎。用于肝肾不足的腰膝酸痛,下肢痿软等症。
续断:补肝肾强筋骨,止血安胎,疗伤续折。用于肝肾不足,腰痛脚弱,风湿痹痛,及跌扑损伤骨折,肿痛等。
生川乌:祛风除湿,散寒止痛。用于风寒湿痹,诸寒疼痛,跌打损伤,麻醉止痛等。
生草乌:祛风除湿,温经止痛。用于风寒湿痹,关节疼痛,心腹冷痛,寒疝疼痛,跌打损伤疼痛,有麻醉止痛作用。
天南星:燥湿化痰祛风解痉;外用消肿止痛。
马钱子:散结消肿,通络止痛。用于跌打损伤,痈疽肿痛,风湿顽痹,麻木瘫痪等,有较强的开通经络,通达关节而止痛的作用。
三七:化瘀止血,活血定痛。用于跌打损伤,瘀滞疼痛,能活血化瘀而消肿止痛,为伤科要药。
血竭:活血疗伤,止血生肌。用于跌打损伤及其他瘀滞心腹疼痛。入血分而散瘀止痛,为伤科要药。
蜈蚣:清热息风,通络,平喘,利尿。用于痹症,风湿热痹及风寒湿痹均可用。
全蝎:熄风止痉,攻毒散结,通络止痛。治顽痹,对风寒湿痹久治不愈,筋脉拘挛,关节变形之顽痹,作用颇佳。
猪牙皂:祛顽痰,通窍开闭,祛风杀虫。辛散走窜之力极强,外用有散结消肿之效。
丁香:温中降逆,温肾助阳。所含挥发油丁香油酚有局部麻醉止痛作用。
花椒:温中止痛,杀虫,止痒。本品挥发油有麻醉止痛作用。
乳香:活血行气止痛,消肿生肌。用于伤科跌打损伤,疮疡痈肿及瘀血阻滞诸痛者。
没药:活血止痛,消肿生肌。
土鳖虫:破血逐瘀,接骨续筋,用于跌打损伤筋伤骨折,瘀肿疼痛。
冰片:开窍醒神,清热止痛。
上述组份科学、合理配伍,互相支持,有效用于治疗骨科疼痛,疗效好,用药安全,并经临床资料得到了充分证明,有关临床资料如下:
1骨科疼痛症的入选标准
选择骨科疼痛的患者100例,其中颈椎病15例、腰椎间盘突出症30例、肩周炎15例、膝骨性关节病20例、髋关节滑膜炎10例、跌打损伤10例。
疗效评定标准
疗效评定:“治愈”临床症状消失,功能活动恢复正常,“显效”临床症状基本或大部分消失,“有效”临床症状明显好转或好转,“无效”临床症状体征无改变。
治疗方案
本发明中药膏的使用方法:患处清洁处理,将药膏贴于患处,药膏贴规格160×120mm,有效成分5g,1贴3天,3贴1疗程。过敏体质慎用,孕妇慎用。
统计学处理
骨科疼痛的患者100例,1-5贴膏药治愈32例,显效40例,有效25例,无效3例;总有效率97%,表明该发明中药膏治疗骨科疼痛效果显著,达到了临床治疗目的,并且在治疗过程中,未见明显不良反应。
为了更详细的说明治疗情况,以下给出典型病例及治疗的疗效情况:
病例1,张XX,男,35岁,银行柜员,间断性颈肩部疼痛、活动受限2年,颈椎曲度变直,部分椎间孔狭窄,颈椎骨质增生,诊断为混合型颈椎病。症状:颈肩部疼痛,颈椎活动受限,右上肢疼痛麻木。使用本膏药4贴,12天症状消失,恢复正常工作,3个月后回访无复发。
病例2,李XX,男,36岁,快递员,间断性腰骶部疼痛2年,腰4/5椎间盘膨出、腰5/骶1椎间盘中央型突出,诊断为腰椎间盘突出症。症状:腰骶部疼痛,腰椎活动受限,休息后稍减轻,久坐劳累后反复发作。使用本膏药5贴,15天症状消失,恢复正常工作,3个月后回访无复发。
病例3,吴XX,女,65岁,退休,双髋关节疼痛,双髋关节关节腔内积液,诊断为髋关节滑膜炎,使用本膏药3贴,9天症状基本消失,正常行走,3个月后回访无复发。
病例4,赵XX,女,30岁,自由职业,不慎扭伤致踝关节疼痛肿胀,活动受限,骨质无异常,周围轻度肿胀,使用本膏药2贴,6天症状基本消失,正常行走,1个月后回访无复发。
病例5,许XX,女,55岁,务农,双膝关节疼痛肿胀,功能活动受限,双膝关节骨质增生,髌上囊少量积液,使用本膏药4贴,12天症状基本消失,正常行走,3个月后回访无复发。
结论
上述临床试验证明,本发明是治疗骨科疼痛的有效药物,配伍精当,疗效显著,无毒无副作用,治愈率高达97%,且材料简单易得,制作工艺简单,耗费成本低,主要用于颈腰椎病、肩周炎、骨性关节病、风湿性关节病、滑膜炎、足跟痛、跌打损伤及骨折等骨科疼痛疾病,具有实际的临床意义和良好的推广应用价值。
Claims (4)
1.一种治疗骨科疼痛的中药膏,其特征在于,该中药膏是由以下重量份数计的原料制成:麻黄15-25份、羌活25-35份、白芷25-35份、防风25-35份、威灵仙25-35份、木瓜25-35份、寻骨风25-35份、海风藤25-35份、虎杖25-35份、山柰15-25份、独活15-25份、当归15-25份、川牛膝15-25份、杜仲25-35份、续断25-35份、生川乌25-35份、生草乌25-35份、天南星15-25份、马钱子25-35份、三七15-25份、血竭15-25份、蜈蚣10-20份、全蝎10-20份、猪牙皂25-35份、丁香25-35份、花椒25-35份、乳香20-35份、没药20-35份、土鳖虫25-35份、冰片25-35份、医用压敏胶80-120份、氮酮4-6份。
2.根据权利要求1所述的治疗骨科疼痛的中药膏,其特征在于,该中药膏是由以下重量份数计的原料制成:麻黄16份、羌活34份、白芷26份、防风34份、威灵仙26份、木瓜34份、寻骨风26份、海风藤34份、虎杖26份、山柰24份、独活16份、当归24份、川牛膝16份、杜仲34份、续断26份、生川乌34份、生草乌26份、天南星24份、马钱子26份、三七24份、血竭16份、蜈蚣19份、全蝎11份、猪牙皂34份、丁香26份、花椒34份、乳香21份、没药34份、土鳖虫26份、冰片34份、医用压敏胶120份、氮酮6份。
3.根据权利要求1所述的治疗骨科疼痛的中药膏,其特征在于,该中药膏是由以下重量份数计的原料制成:麻黄20份、羌活30份、白芷30份、防风30份、威灵仙30份、木瓜30份、寻骨风30份、海风藤30份、虎杖30份、山柰20份、独活20份、当归20份、川牛膝20份、杜仲30份、续断30份、生川乌30份、生草乌30份、天南星20份、马钱子30份、三七20份、血竭20份、蜈蚣15份、全蝎15份、猪牙皂30份、丁香30份、花椒30份、乳香25份、没药25份、土鳖虫30份、冰片30份、医用压敏胶100份、氮酮5份。
4.权利要求1或2-3任一项所述的治疗骨科疼痛的中药膏的制备方法,其特征在于,首先将麻黄、羌活、白芷、防风、威灵仙、木瓜、寻骨风、海风藤、虎杖、山柰、独活、当归、川牛膝、杜仲、续断、生川乌、生草乌、天南星、马钱子粉碎成细末,加等量灭菌用水,浓缩至原重量的80%,制成水煮浸膏,备用;再将三七、血竭、蜈蚣、全蝎、猪牙皂、丁香、花椒、乳香、没药、土鳖虫、冰片粉碎成细末,加入等量体积浓度为95%的医用酒精,浸泡1周,制成乙醇浸膏,备用;最后将水煮浸膏:乙醇浸膏按原料药重量比为2:1混合,加热干燥成混合药粉,将医用压敏胶加热融化,加入混合药粉,再加入氮酮,比例为医用压敏胶:混合药粉:氮酮=20:15:1,搅拌均匀成膏,在医用膏药空白贴布上摊制成型,即得。
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