CN109966451A - 一种正骨止痛的中药组合物 - Google Patents

一种正骨止痛的中药组合物 Download PDF

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CN109966451A
CN109966451A CN201910359889.5A CN201910359889A CN109966451A CN 109966451 A CN109966451 A CN 109966451A CN 201910359889 A CN201910359889 A CN 201910359889A CN 109966451 A CN109966451 A CN 109966451A
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bone
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谢晓龙
王海亮
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Meishan Traditional Chinese Medicine Hospital (meishan Dongpo District People's Hospital)
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Meishan Traditional Chinese Medicine Hospital (meishan Dongpo District People's Hospital)
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Abstract

一种正骨止痛的中药组合物，包括茜草8‑15份、苏木10‑20份、儿茶4‑10份、制乳香5‑10份、制没药5‑10份、大血藤10‑20份、三棱5‑15份、莪术5‑15份、枳壳10‑20份、地鳖8‑12份、生大黄12‑18份、白芷10‑15份、姜黄6‑15份、合欢皮6‑15份、泽兰10‑18份、当归5‑15份、川芎5‑15份、制川乌4‑8份、制草乌4‑8份、蜈蚣3‑8份、藿香6‑10份、骨碎补8‑12份、马钱子3‑8份、茯苓皮6‑10份、天花粉8‑12份等，具有化瘀消肿、接骨续筋、祛风除湿、舒筋通络、解毒散寒之效，正骨效果好。

Description

一种正骨止痛的中药组合物
技术领域
本发明属于中药技术领域，具体涉及一种正骨止痛的中药组合物。
背景技术
正骨，中医指用推、拽、按、捺等手法治疗骨折、脱臼等筋骨损伤疾病。正骨对象主要是外力作用所致的骨、关节和软组织的损伤，但也包括同类原因引致的体内脏器损伤，常规的治疗方法是整复、固定和功能锻炼，整复使移位的骨折端正确地复位并治疗软组织损伤的一种疗术，往往给患者造成极大的痛苦，由于使受伤部位气血受阻，增加了患者的痛苦，同时也延长了愈合时间，加重了后期功能锻炼的负担。筋骨损伤还可通过内服药物治疗和外贴膏药治疗，服药物治疗多针对肌肉扭伤病人，一般采用跌打丸、大活络丸、花红片等，但内服药物存在对病灶的治疗效果不显著，服药时间长，易对人体产生副作用，外贴膏药治疗主要是将药物的药效通过皮肤表面，由表及里对病灶处进行直接治疗，但是对皮肤刺激性大，易造成过敏，加重淤血红肿。
发明内容
本发明的目的在于：针对上述现有筋骨损伤采用外贴膏药治疗易刺激皮肤、造成过敏的问题，本发明提供一种正骨止痛的中药组合物，该中药组合物敷于患处，药物成分由表及里，保证气血通畅，具有化瘀消肿、接骨续筋、祛风除湿、舒筋通络、解毒散寒之效，正骨效果好。
本发明采用的技术方案如下：
一种正骨止痛的中药组合物，包括以下重量份数的原料：茜草8-15份、苏木10-20份、儿茶4-10份、制乳香5-10份、制没药5-10份、大血藤10-20份、三棱5-15份、莪术5-15份、枳壳10-20份、地鳖8-12份、生大黄12-18份、白芷10-15份、姜黄6-15份、合欢皮6-15份、泽兰10-18份、当归5-15份、川芎5-15份、制川乌4-8份、制草乌4-8份、蜈蚣3-8份、藿香6-10份、骨碎补8-12份、马钱子3-8份、茯苓皮6-10份、天花粉8-12份、王不留行3-9份、王加皮5-15份、白芥子5-15份、紫荆皮5-15份、月石10-20份、寒水石10-20份。
一种正骨止痛的中药组合物，包括以下重量份数的原料：茜草8-13份、苏木12-18份、儿茶4-8份、制乳香6-9份、制没药7-9份、大血藤13-17份、三棱8-12份、莪术8-12份、枳壳14-16份、地鳖9-11份、生大黄14-16份、白芷11-13份、姜黄8-12份、合欢皮8-13份、泽兰12-18份、当归8-12份、川芎8-12份、制川乌5-7份、制草乌5-7份、蜈蚣3-6份、藿香7-9份、骨碎补9-11份、马钱子4-7份、茯苓皮7-9份、天花粉9-11份、王不留行4-8份、王加皮8-12份、白芥子8-12份、紫荆皮8-12份、月石14-16份、寒水石14-16份。
一种正骨止痛的中药组合物，包括以下重量份数的原料：茜草10份、苏木15份、儿茶6份、制乳香8份、制没药8份、大血藤15份、三棱10份、莪术10份、枳壳15份、地鳖10份、生大黄15份、白芷12份、姜黄10份、合欢皮10份、泽兰15份、当归10份、川芎10份、制川乌6份、制草乌6份、蜈蚣5份、藿香8份、骨碎补10份、马钱子6份、茯苓皮8份、天花粉10份、王不留行6份、王加皮10份、白芥子10份、紫荆皮10份、月石15份、寒水石15份。
本发明药理作用如下：
茜草：苦，寒，归肝经；凉血化瘀止血，通经；
苏木：甘、咸、辛，平，归心、肝经；活血疗伤，祛瘀通经；
儿茶：苦、涩，凉，归心、肺经；活血疗伤，止血生肌，收湿敛疮，清肺化痰；
制乳香：辛、苦，温。归心、肝、脾经；活血行气止痛，消肿生肌：具有镇痛、消炎作用，能促进多核白血球增加，以吞噬死亡的血球及细胞，改善新陈代谢；
制没药：辛、苦，平，归心、肝、脾经；活血止痛，消肿生肌；
大血藤：苦，平，归大肠、肝经；清热解毒，活血，祛风，止痛；
三棱：辛、苦，平，归肝、脾经；破血行气，消积止痛；
莪术：辛、苦，温，归肝、脾经；破血行气，消积止痛；
枳壳：苦、辛、酸，温，归脾、胃、大肠经；破气消积，化痰除痞；
地鳖：咸，寒，有小毒，归肝经；破血逐瘀，续筋接骨；
生大黄：苦，寒，归脾、胃、大肠、肝、心包经；泻下攻积，清热泻火，凉血解毒，逐瘀通经；
白芷：辛，温，归肺、胃、大肠经；解表散寒，祛风止痛，通鼻窍，燥湿止带，消肿排脓；
姜黄：辛、苦，温，归肝、脾经；活血行气，通经止痛；
合欢皮：甘，平，归心、肝、肺经；解郁安神，活血消肿；
泽兰：苦、辛，微温，归肝、脾经；活血调经，利水消肿；
当归：甘、辛，温，归肝、心、脾经；补血调经，活血止痛，润肠通便；
川芎：辛，温，归肝、胆、心包经；活血行气，祛风止痛；
制川乌：辛、苦，热，有大毒，归心、肝、肾、脾经；祛风湿，温经止痛；
制草乌：辛、苦，热，有大毒，归心、肝、肾、脾经；祛风湿，温经止痛；
蜈蚣：辛，温，有毒，归肝经；息风止痉、通络止痛、解毒散结；可治疗骨髓炎，提高免疫功能；
藿香：辛，微温，归脾、胃、肺经；化湿，止呕，解暑；
骨碎补：苦，温，归肝、肾经；活血续伤，补肾强骨；
马钱子：苦、寒，有大毒，归肝、脾经；散结消肿，通络止痛；
茯苓皮：甘、淡，平，归心、脾、肾经；利水消肿，健脾，宁心；
天花粉：甘、微苦，微寒，归肺、胃经；补肺，清热泻火，生津止渴，消肿排脓；
王不留行：苦，平，归肝、胃经；活血通经，下乳消痈，利尿通淋；
王加皮：辛、苦，温，归肝、肾经；祛风湿，补肝肾，强筋骨，利水；具有抗菌消炎、镇痛、增强免疫的功效；
白芥子：辛，温，归脾、胃经；温肺化痰，利气散结，通络止痛；
紫荆皮：苦，平，归肝经；活血，通淋，解毒；
月石：甘、咸，凉，归肺、胃经；清热消痰；解毒防腐；
寒水石：辛、咸，寒，归心、胃肾经；凉血止血、散瘀消肿，清热泻火。
现有外贴膏药一般以添加接骨木、续断等接骨续筋为主，活血化瘀、消肿止痛为辅，但是，筋骨损伤时本身就气血受阻，气血受阻则阻碍药物成分运行，难以抵达筋骨损伤处，接骨续筋疗效差。本发明以苏木、儿茶、制乳香、制没药、大血藤、泽兰等活血，三棱、莪术破血，辅以行气止痛之效，以枳壳破气消积、化痰除痞，白芥子、月石等化痰，促进气血通畅，肺主气，主一身五脏六腑之气，中焦脾胃受纳水谷，脾气健运，气血得以化生，故气虚多与肺、脾二脏相关，本发明以白芥子温肺、天花粉补肺、茯苓皮健脾、王加皮补肝肾，治气虚，则血液运行有力，本发明还以白芷解表散寒、王加皮祛风湿，茜草、寒水石、生大黄凉血、清热，缓解血寒及血热造成的血液运行不畅，上述各成分合理配伍，协同作用，快速达到气血通畅之效，然后再以地鳖、骨碎补、王加皮接骨续筋，正骨效果好，此外，蜈蚣可治疗骨髓炎，王加皮、制乳香等均具有抗炎作用。
综上所述，由于采用了上述技术方案，本发明的有益效果是：以具有活血、破血、行气之效的成分为主，保证筋骨损伤处气血通畅，再以地鳖、骨碎补、王加皮等接骨续筋为辅，制乳香、制没药等消肿生肌，蜈蚣、马钱子、白芥子等通络止痛，共为佐，达到化瘀消肿、接骨续筋、祛风除湿、舒筋通络、解毒散寒之效，正骨效果好。
具体实施方式
本说明书中公开的所有特征，除了互相排斥的特征和/或步骤以外，均可以以任何方式组合。
实施例1
一种正骨止痛的中药组合物，包括以下重量份数的原料：茜草8份、苏木10份、儿茶4.5份、制乳香5份、制没药5.2份、大血藤11份、三棱5份、莪术5份、枳壳10份、地鳖8份、生大黄13份、白芷10份、姜黄6份、合欢皮6份、泽兰10份、当归5份、川芎5份、制川乌4份、制草乌4份、蜈蚣3份、藿香6份、骨碎补8份、马钱子3份、茯苓皮6份、天花粉8份、王不留行3份、王加皮5份、白芥子5份、紫荆皮5份、月石11份、寒水石12份。
实施例2
本实施例与实施例1的区别仅在于：一种正骨止痛的中药组合物，包括以下重量份数的原料：茜草8.5份、苏木12份、儿茶5份、制乳香6份、制没药7份、大血藤13份、三棱8份、莪术8份、枳壳14份、地鳖9份、生大黄14份、白芷11份、姜黄8份、合欢皮8份、泽兰12份、当归8份、川芎8份、制川乌5份、制草乌5份、蜈蚣3份、藿香7份、骨碎补9份、马钱子4份、茯苓皮7份、天花粉9份、王不留行4份、王加皮8份、白芥子8份、紫荆皮8份、月石14份、寒水石14份。
实施例3
本实施例与实施例1的区别仅在于：一种正骨止痛的中药组合物，包括以下重量份数的原料：茜草10份、苏木15份、儿茶6份、制乳香8份、制没药8份、大血藤15份、三棱10份、莪术10份、枳壳15份、地鳖10份、生大黄15份、白芷12份、姜黄10份、合欢皮10份、泽兰15份、当归10份、川芎10份、制川乌6份、制草乌6份、蜈蚣5份、藿香8份、骨碎补10份、马钱子6份、茯苓皮8份、天花粉10份、王不留行6份、王加皮10份、白芥子10份、紫荆皮10份、月石15份、寒水石15份。
实施例4
本实施例与实施例1的区别仅在于：一种正骨止痛的中药组合物，包括以下重量份数的原料：茜草13份、苏木18份、儿茶8份、制乳香9份、制没药9份、大血藤17份、三棱12份、莪术12份、枳壳16份、地鳖11份、生大黄16份、白芷13份、姜黄12份、合欢皮13份、泽兰18份、当归12份、川芎12份、制川乌7份、制草乌7份、蜈蚣5.5份、藿香9份、骨碎补11份、马钱子7份、茯苓皮9份、天花粉11份、王不留行8份、王加皮12份、白芥子12份、紫荆皮12份、月石16份、寒水石16份。
实施例5
本实施例与实施例1的区别仅在于：一种正骨止痛的中药组合物，包括以下重量份数的原料：茜草15份、苏木20份、儿茶10份、制乳香10份、制没药10份、大血藤20份、三棱15份、莪术15份、枳壳20份、地鳖12份、生大黄18份、白芷15份、姜黄15份、合欢皮15份、泽兰18份、当归15份、川芎15份、制川乌8份、制草乌8份、蜈蚣6.8份、藿香10份、骨碎补12份、马钱子8份、茯苓皮10份、天花粉12份、王不留行9份、王加皮15份、白芥子15份、紫荆皮15份、月石20份、寒水石20份。
实施例6
按照实施例4的配方，将各成分打成100目细粉，将细粉混合后装入容器中，使用时取出50g加入适量沸水调敷，将调制好的细粉均匀涂于纱布上，纱布尺寸为10*8cm，再用一张同样大小的纱布覆盖，将适量的紫草油涂于上层纱布上，将制备好的药膏敷于患处，绷带固定，每日更换。
临床资料
1、一般资料均选自我院近5年收治的踝关节扭伤的门诊患者，病例随机分为治疗组40例和对照组40例，治疗组男18例，女22例，年龄20-30岁，病程1-5天，对照组男15例，女25例，年龄为22-30岁，病程1-5天。治疗组和对照组在性别、年龄、病程方面经统计学处理差异无显著性(P＞0.05)，具有可比性。
2、诊断标准：
(1)临床症状：踝关节肿胀，屈伸活动受限，局部青紫瘀斑；(2)特点：均有明显扭伤史，关节活动受限，无法正常站立及行走；(3)排除骨折等，辅助检查提示仅为踝关节扭伤。
3、治疗方法：
治疗组使用本发明所述正骨止痛散，敷于患处，每日一次；对照组口服塞来昔布胶囊，每天0.2g。治疗组和对照组均15天为1个疗程，两组均连续进行两个疗程。
4、疗效标准
治愈：关节胀痛消失，屈伸功能活动恢复正常，能正常活动；
显效：关节胀痛明显减轻，屈伸功能基本恢复，适当负重；
有效：关节胀痛有所减轻，屈伸功能基本恢复或好转，无法负重；
无效：和治疗前相比，各方面均无好转。
5、治疗结果
治疗组40例，其中治愈20例，显效10例，有效8例，无效2例，总有效率95％；对照组40例，其中治愈8例，显效12例，有效10例，无效10例，总有效率75％。治疗组治愈率、总有效率明显优于对照组。
如上所述即为本发明的实施例。本发明不局限于上述实施方式，任何人应该得知在本发明的启示下做出的结构变化，凡是与本发明具有相同或相近的技术方案，均落入本发明的保护范围之内。

Claims (3)

1.一种正骨止痛的中药组合物，其特征在于，包括以下重量份数的原料：茜草8-15份、苏木10-20份、儿茶4-10份、制乳香5-10份、制没药5-10份、大血藤10-20份、三棱5-15份、莪术5-15份、枳壳10-20份、地鳖8-12份、生大黄12-18份、白芷10-15份、姜黄6-15份、合欢皮6-15份、泽兰10-18份、当归5-15份、川芎5-15份、制川乌4-8份、制草乌4-8份、蜈蚣3-8份、藿香6-10份、骨碎补8-12份、马钱子3-8份、茯苓皮6-10份、天花粉8-12份、王不留行3-9份、王加皮5-15份、白芥子5-15份、紫荆皮5-15份、月石10-20份、寒水石10-20份。
2.根据权利要求1所述的一种正骨止痛的中药组合物，其特征在于，包括以下重量份数的原料：茜草8-13份、苏木12-18份、儿茶4-8份、制乳香6-9份、制没药7-9份、大血藤13-17份、三棱8-12份、莪术8-12份、枳壳14-16份、地鳖9-11份、生大黄14-16份、白芷11-13份、姜黄8-12份、合欢皮8-13份、泽兰12-18份、当归8-12份、川芎8-12份、制川乌5-7份、制草乌5-7份、蜈蚣3-6份、藿香7-9份、骨碎补9-11份、马钱子4-7份、茯苓皮7-9份、天花粉9-11份、王不留行4-8份、王加皮8-12份、白芥子8-12份、紫荆皮8-12份、月石14-16份、寒水石14-16份。
3.根据权利要求1或2所述的一种正骨止痛的中药组合物，其特征在于，包括以下重量份数的原料：茜草10份、苏木15份、儿茶6份、制乳香8份、制没药8份、大血藤15份、三棱10份、莪术10份、枳壳15份、地鳖10份、生大黄15份、白芷12份、姜黄10份、合欢皮10份、泽兰15份、当归10份、川芎10份、制川乌6份、制草乌6份、蜈蚣5份、藿香8份、骨碎补10份、马钱子6份、茯苓皮8份、天花粉10份、王不留行6份、王加皮10份、白芥子10份、紫荆皮10份、月石15份、寒水石15份。
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