CN107157991A - 用于缓解尿频的延长释放制剂及其使用方法 - Google Patents

用于缓解尿频的延长释放制剂及其使用方法 Download PDF

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Publication number
CN107157991A
CN107157991A CN201710373440.5A CN201710373440A CN107157991A CN 107157991 A CN107157991 A CN 107157991A CN 201710373440 A CN201710373440 A CN 201710373440A CN 107157991 A CN107157991 A CN 107157991A
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China
Prior art keywords
release
pharmaceutical composition
analgesic
hours
analgesics
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CN201710373440.5A
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English (en)
Chinese (zh)
Inventor
大卫·A·迪尔
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Wellesley Pharmaceuticals LLC
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Wellesley Pharmaceuticals LLC
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Filing date
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Priority claimed from US13/424,000 external-priority patent/US8236857B2/en
Priority claimed from US13/487,348 external-priority patent/US20120244221A1/en
Application filed by Wellesley Pharmaceuticals LLC filed Critical Wellesley Pharmaceuticals LLC
Publication of CN107157991A publication Critical patent/CN107157991A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
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    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
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    • A61P13/10—Drugs for disorders of the urinary system of the bladder
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
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    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201710373440.5A 2012-03-19 2013-03-13 用于缓解尿频的延长释放制剂及其使用方法 Pending CN107157991A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US13/424,000 US8236857B2 (en) 2010-07-08 2012-03-19 Extended-release formulation for reducing the frequency of urination and method of use thereof
US13/424,000 2012-03-19
US13/487,348 US20120244221A1 (en) 2010-07-08 2012-06-04 Extended-release formulation for reducing the frequency of urination and method of use thereof
US13/487,348 2012-06-04
CN201380015062.3A CN104302284A (zh) 2012-03-19 2013-03-13 用于缓解尿频的延长释放制剂及其使用方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201380015062.3A Division CN104302284A (zh) 2012-03-19 2013-03-13 用于缓解尿频的延长释放制剂及其使用方法

Publications (1)

Publication Number Publication Date
CN107157991A true CN107157991A (zh) 2017-09-15

Family

ID=49223209

Family Applications (4)

Application Number Title Priority Date Filing Date
CN201710373440.5A Pending CN107157991A (zh) 2012-03-19 2013-03-13 用于缓解尿频的延长释放制剂及其使用方法
CN201380015062.3A Pending CN104302284A (zh) 2012-03-19 2013-03-13 用于缓解尿频的延长释放制剂及其使用方法
CN201380015025.2A Pending CN104321056A (zh) 2012-03-19 2013-03-14 用于缓解尿频的延长释放制剂及其使用方法
CN201711086139.2A Pending CN107789626A (zh) 2012-03-19 2013-03-14 用于缓解尿频的延长释放制剂及其使用方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
CN201380015062.3A Pending CN104302284A (zh) 2012-03-19 2013-03-13 用于缓解尿频的延长释放制剂及其使用方法
CN201380015025.2A Pending CN104321056A (zh) 2012-03-19 2013-03-14 用于缓解尿频的延长释放制剂及其使用方法
CN201711086139.2A Pending CN107789626A (zh) 2012-03-19 2013-03-14 用于缓解尿频的延长释放制剂及其使用方法

Country Status (15)

Country Link
EP (2) EP2827852A4 (enrdf_load_stackoverflow)
JP (5) JP2015510928A (enrdf_load_stackoverflow)
KR (4) KR20140134333A (enrdf_load_stackoverflow)
CN (4) CN107157991A (enrdf_load_stackoverflow)
AU (4) AU2013235518B2 (enrdf_load_stackoverflow)
BR (2) BR112014020271A8 (enrdf_load_stackoverflow)
CA (2) CA2866853A1 (enrdf_load_stackoverflow)
HK (3) HK1204553A1 (enrdf_load_stackoverflow)
MX (3) MX2014011128A (enrdf_load_stackoverflow)
MY (2) MY174090A (enrdf_load_stackoverflow)
NZ (6) NZ718163A (enrdf_load_stackoverflow)
RU (3) RU2669565C2 (enrdf_load_stackoverflow)
SG (2) SG11201500408VA (enrdf_load_stackoverflow)
WO (2) WO2013142197A1 (enrdf_load_stackoverflow)
ZA (2) ZA201405862B (enrdf_load_stackoverflow)

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RU2016152226A (ru) * 2014-06-06 2018-07-09 УЭЛЛСЛИ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи Фармацевтический состав для уменьшения частоты мочеиспускания и способ его применения
KR101809908B1 (ko) * 2014-07-21 2018-01-25 주식회사 종근당 5-알파환원효소억제제를 포함하는 조성물
AU2015349811B2 (en) * 2014-11-20 2021-05-06 Acerus Pharmaceuticals USA, LLC Methods and compositions comprising desmopressin in combination with an alpha-adrenergic receptor antagonist
AU2016331871A1 (en) * 2015-09-30 2018-05-17 Wellesley Pharmaceuticals, Llc Composition for reducing the frequency of urination, method of making and use thereof
CN108430465A (zh) * 2015-09-30 2018-08-21 韦尔斯利医药有限公司 用于缓解尿频的组合物、其制造方法和用途
CN105238124B (zh) * 2015-11-16 2018-02-09 太仓东能环保设备有限公司 一种抗菌腻子粉
JP6294924B2 (ja) 2016-09-05 2018-03-14 株式会社Ｓｕｂａｒｕ 車両の走行制御装置
JP2019031556A (ja) * 2018-10-31 2019-02-28 ウェルズリー ファーマスーティカルズ、エルエルシー 排尿頻度を減少させるための医薬製剤およびその使用の方法

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JP2015510936A (ja) 2015-04-13
SG11201500408VA (en) 2015-03-30
BR112014020271A2 (enrdf_load_stackoverflow) 2017-06-20
EP2827852A4 (en) 2016-03-02
MX2019008817A (es) 2019-09-26
KR20190003840A (ko) 2019-01-09
JP2015510928A (ja) 2015-04-13
EP2827851A4 (en) 2015-10-14
MY175764A (en) 2020-07-08
KR20140134333A (ko) 2014-11-21
CN107789626A (zh) 2018-03-13
NZ714662A (en) 2016-08-26
RU2599017C2 (ru) 2016-10-10
CA2866853A1 (en) 2013-07-26
AU2013235507B2 (en) 2017-03-23
MY174090A (en) 2020-03-09
CA2866755A1 (en) 2013-09-26
CN104321056A (zh) 2015-01-28
AU2017203139A1 (en) 2017-06-01
AU2017203246A1 (en) 2017-06-08
NZ630471A (en) 2016-04-29
AU2017203246B2 (en) 2018-10-18
JP2018024693A (ja) 2018-02-15
BR112014020113A8 (pt) 2017-07-11
NZ628079A (en) 2016-05-27
EP2827852A1 (en) 2015-01-28
RU2669565C2 (ru) 2018-10-12
RU2016133305A3 (enrdf_load_stackoverflow) 2018-12-10
BR112014020271A8 (pt) 2017-07-11
RU2014142025A (ru) 2016-05-10
NZ714288A (en) 2016-12-23
HK1251469A1 (zh) 2019-02-01
AU2013235507A1 (en) 2014-08-21
WO2013142197A1 (en) 2013-09-26
JP2018138602A (ja) 2018-09-06
HK1204553A1 (en) 2015-11-27
AU2013235518A2 (en) 2014-10-09
AU2017203139B2 (en) 2018-07-19
NZ712594A (en) 2016-09-30
EP2827851A1 (en) 2015-01-28
NZ718163A (en) 2017-09-29
AU2013235518B2 (en) 2017-03-02
WO2013142274A1 (en) 2013-09-26
ZA201405862B (en) 2016-08-31
KR20140134284A (ko) 2014-11-21
HK1243921A1 (zh) 2018-07-27
MX2014011128A (es) 2015-08-10
MX2014011129A (es) 2015-08-10
CN104302284A (zh) 2015-01-21
ZA201406146B (en) 2016-08-31
JP2016172752A (ja) 2016-09-29
SG11201500409SA (en) 2015-03-30
KR20170015537A (ko) 2017-02-08
AU2013235518A1 (en) 2014-09-25
BR112014020113A2 (enrdf_load_stackoverflow) 2017-06-20
RU2016133305A (ru) 2018-12-10
RU2014142066A (ru) 2016-05-10

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