CN107137751A - A kind of medical dressing of the globulin containing wheat germ - Google Patents

A kind of medical dressing of the globulin containing wheat germ Download PDF

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Publication number
CN107137751A
CN107137751A CN201710360219.6A CN201710360219A CN107137751A CN 107137751 A CN107137751 A CN 107137751A CN 201710360219 A CN201710360219 A CN 201710360219A CN 107137751 A CN107137751 A CN 107137751A
Authority
CN
China
Prior art keywords
parts
wheat germ
globulin
medical dressing
wound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710360219.6A
Other languages
Chinese (zh)
Inventor
黄继红
张相生
吴丽
巴欣毅
张荣生
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henan Biological Technology Co Ltd
Original Assignee
Henan Biological Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henan Biological Technology Co Ltd filed Critical Henan Biological Technology Co Ltd
Priority to CN201710360219.6A priority Critical patent/CN107137751A/en
Publication of CN107137751A publication Critical patent/CN107137751A/en
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A61L2300/104—Silver, e.g. silver sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents

Abstract

The present invention relates to a kind of medical dressing of globulin containing wheat germ, belong to medical supplies technical field, wherein the parts by weight of feed components are 1~10 part of calcium alginate, 20 ~ 30 parts of sodium alginate, 1 ~ 10 part of chitosan, 3 ~ 8 parts of glycerine, 1 ~ 6 part of wheat germ globulin, 0.0001 ~ 0.0005 part of Nano Silver, 180 ~ 220 parts of deionized water；The medical dressing utilizes the wheat germ globulin with immune effect, with good anti-inflammatory, antibacterial and promotion new granulation tissue and epithelial cell growth, can greatly promote the healing effect of wound, the deeper situation of the wound that is particularly suitable for use in.

Description

A kind of medical dressing of the globulin containing wheat germ
Technical field
The present invention relates to a kind of medical dressing of globulin containing wheat germ, belong to medical supplies technical field.
Background technology
Medical dressing, is the articles for use of bag wound, the medical material to cover sore, wound or other infringements.With to the surface of a wound The physiopathologic further investigation of agglutination, understanding of the people to wound is also more and more deep, so as to result in Medical wounded surface dressing is updated and developed.Today, new surface of a wound nursing dressing has occurred and that for early stage Revolutionary change, and the medical dressing of a variety of different performances is available for clinical nursing staff to select.
Novel medical dressing is divided into film class, Hydrogels, alginic acid salt, foam class, hydrocolloid class, medicinal class dressing. Wherein new alginic acid salt dressing main component is derived from the algae in seawater, it be utilize algae in like fibrous element can not be molten The dressing that the polysaccharide alginate of solution is made.Alginate dressing can absorb wound exudate formation gel, form soft on the surface of a wound The semi-solid material of similar gels, a moist environment is provided for the surface of a wound, improves the power of regeneration of epidermal cell, accelerates epidermis thin Born of the same parents move.Chitosan is extracted from crab shell, dried small shrimp or the film of fungi and through a kind of poly osamine formed by de- second phthalein, right Body is nontoxic, has good compatibility with organism, it is easy to chemical modification, and has preferable antibacterial to make to many bacteriums and fungi With, also good biodegradability, it has hemostasis to make wound fluid good water absorption, good permeability to wound oozing of blood With, and can wound healing, and can as medicine slow release vehicle.
Alginate and chitosan composite usage can improve the single poor adhesion caused by, comply with medical dressing Property and it is elastic poor the shortcomings of, therefore to this using both exploitation dressing it is also more.CN201010106134.3 discloses one The medical dressing of novel antibacterial is planted, by chitosan, chitosan oligosaccharide and enhancing macromolecule composition, wherein chitosan, chitosan oligosaccharide account for total matter More than the 85-95% of amount, wherein, enhancing macromolecule is selected from：Sodium alginate, or glucan, or hyaluronic acid macromolecule, or collagen One or more in albumen；A kind of novel skin regrown material disclosed in CN201410182975.0, wherein gel layer by Include alginate and chitosan, and grease microcapsule powder, Nano Silver etc., with the protection surface of a wound, relieve pain, stop blooding, disappear Scorching, promotion new granulation tissue and epithelial cell growth, accelerate wound healing etc., anti-microbial property is good, and biological safety is good etc. Advantage.
Although dressing alginate and chitosan composite usage are good in the advantage of medical dressing, especially in anti-microbial property side Face, but when some wounds are deep, dressing only by alginate and chitosan and is compounded some other conventional Composition, effect is also preferable not to the utmost.
The content of the invention
There is provided a kind of medical dressing of globulin containing wheat germ, the Medical coating for the problem of present invention exists for prior art Material is using the wheat germ globulin with immune effect, with good anti-inflammatory, antibacterial and promotion new granulation tissue and epithelium Cell growth, can greatly promote the healing effect of wound, the deeper situation of the wound that is particularly suitable for use in.
In order to solve the above problems, the technical solution adopted in the present invention is：A kind of medical dressing of the globulin containing wheat germ, The parts by weight of feed components are：1~10 part of calcium alginate, 20 ~ 30 parts of sodium alginate, 1 ~ 10 part of chitosan, glycerine 3 ~ 8 Part, 1 ~ 6 part of wheat germ globulin, 0.0001 ~ 0.0005 part of Nano Silver, 180 ~ 220 parts of deionized water.
The beneficial effects of the invention are as follows：The medical dressing for a kind of globulin containing wheat germ that the present invention is provided, in antibacterial effect Preferably, on the basis of using the medical dressing of more universal alginate and chitosan, it make use of the wheat germ with immune effect Globulin so that final products have good anti-inflammatory, antibacterial and promote new granulation tissue and epithelial cell growth, can be big The healing effect of big lifting wound, the deeper situation of the wound that is particularly suitable for use in.Further, since using the working condition of original dressing With equipment, therefore the production cost advantageously reduced, suitable for industrial production application.
Embodiment
The present invention is described in further details below by embodiment, these embodiments are only used for illustrating the present invention, and Do not limit the scope of the invention.
Embodiment 1：
A kind of medical dressing of globulin containing wheat germ, the parts by weight of feed components are：
1 part of calcium alginate, 20 parts of sodium alginate, 1 part of chitosan, 3 parts of glycerine, 1 part of wheat germ globulin, Nano Silver 0.0001 Part, 180 parts of deionized water.
Embodiment 2：
10 parts of calcium alginate, 30 parts of sodium alginate, 10 parts of chitosan, 8 parts of glycerine, 6 parts of wheat germ globulin, Nano Silver 0.0005 Part, 220 parts of deionized water.
Embodiment 3：
5 parts of calcium alginate, 25 parts of sodium alginate, 5 parts of chitosan, 6 parts of glycerine, 4 parts of wheat germ globulin, Nano Silver 0.0003 Part, 200 parts of deionized water.
Embodiment 4：
3 parts of calcium alginate, 22 parts of sodium alginate, 2.5 parts of chitosan, 5 parts of glycerine, 3 parts of wheat germ globulin, Nano Silver 0.0002 Part, 190 parts of deionized water.
Embodiment 5：
9 parts of calcium alginate, 27 parts of sodium alginate, 8 parts of chitosan, 7 parts of glycerine, 5.5 parts of wheat germ globulin, Nano Silver 0.0004 Part, 210 parts of deionized water.

Claims (1)

1. a kind of medical dressing of globulin containing wheat germ, it is characterised in that：The parts by weight of feed components are：Calcium alginate 1~ 10 parts, 20 ~ 30 parts of sodium alginate, 1 ~ 10 part of chitosan, 3 ~ 8 parts of glycerine, 1 ~ 6 part of wheat germ globulin, Nano Silver 0.0001 ~ 0.0005 part, 180 ~ 220 parts of deionized water.
CN201710360219.6A 2017-05-20 2017-05-20 A kind of medical dressing of the globulin containing wheat germ Pending CN107137751A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710360219.6A CN107137751A (en) 2017-05-20 2017-05-20 A kind of medical dressing of the globulin containing wheat germ

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710360219.6A CN107137751A (en) 2017-05-20 2017-05-20 A kind of medical dressing of the globulin containing wheat germ

Publications (1)

Publication Number Publication Date
CN107137751A true CN107137751A (en) 2017-09-08

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710360219.6A Pending CN107137751A (en) 2017-05-20 2017-05-20 A kind of medical dressing of the globulin containing wheat germ

Country Status (1)

Country Link
CN (1) CN107137751A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110075347A (en) * 2019-05-19 2019-08-02 青岛海之林生物科技开发有限公司 A kind of water-soluble seaweed calcium activated-chitosan oligosaccharide-polypeptide hydrogel and preparation method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103656730A (en) * 2013-12-10 2014-03-26 徐花 Medical chitosan dressing
CN104288826A (en) * 2014-09-26 2015-01-21 张明 Medical rapid chitosan haemostatic wound dressing
CN104324411A (en) * 2014-09-28 2015-02-04 张亚峰 Medical natural marine organism dressing
CN106390178A (en) * 2016-11-27 2017-02-15 威海蓝印海洋生物科技有限公司 Medical natural marine biological dressing
CN106427179A (en) * 2016-09-22 2017-02-22 河南工业大学 Preparation method of wheat germ protein hemostatic bandage

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103656730A (en) * 2013-12-10 2014-03-26 徐花 Medical chitosan dressing
CN104288826A (en) * 2014-09-26 2015-01-21 张明 Medical rapid chitosan haemostatic wound dressing
CN104324411A (en) * 2014-09-28 2015-02-04 张亚峰 Medical natural marine organism dressing
CN106427179A (en) * 2016-09-22 2017-02-22 河南工业大学 Preparation method of wheat germ protein hemostatic bandage
CN106390178A (en) * 2016-11-27 2017-02-15 威海蓝印海洋生物科技有限公司 Medical natural marine biological dressing

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
毕振原等: "麦胚球蛋白的体外抗炎活性研究", 《河南工业大学学报（自然科学版）》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110075347A (en) * 2019-05-19 2019-08-02 青岛海之林生物科技开发有限公司 A kind of water-soluble seaweed calcium activated-chitosan oligosaccharide-polypeptide hydrogel and preparation method thereof
CN110075347B (en) * 2019-05-19 2021-12-03 青岛海之林生物科技开发有限公司 Water-soluble seaweed active calcium-chitosan oligosaccharide-polypeptide hydrogel and preparation method thereof

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Application publication date: 20170908