CN105616296B - A kind of poplar Chinese holly flower itching-relieve skin-care mud - Google Patents
A kind of poplar Chinese holly flower itching-relieve skin-care mud Download PDFInfo
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- CN105616296B CN105616296B CN201610089142.9A CN201610089142A CN105616296B CN 105616296 B CN105616296 B CN 105616296B CN 201610089142 A CN201610089142 A CN 201610089142A CN 105616296 B CN105616296 B CN 105616296B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/733—Alginic acid; Salts thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- Animal Behavior & Ethology (AREA)
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Abstract
The invention discloses a kind of poplar Chinese holly flower itching-relieve skin-care mud, are made of raw material from the following weight：Poplar Chinese holly spends 12~20 parts, 1~3 part of sodium alginate, 1~3 part of chitosan.Poplar Chinese holly flower itching-relieve skin-care mud modulates, the pureed mixture of texture lubrication fine and smooth in feel after stirring with warm water, directly smear it is clean after itch skin, antipruritic, antibacterial, anti-inflammatory and the multi-efficiency of skin care can be played.Raw material sources of the present invention are extensive, low in cost, prepare strong operability, processing easy to produce.Product is sealed for storing for a long time in dry fine-powdered, is convenient for carrying and uses, have broad application prospects.
Description
Technical field
The invention belongs to cosmetic technical fields, and in particular to a kind of poplar Chinese holly flower itching-relieve skin-care mud.
Background technique
Pruitus is most painful in a kind of symptom and skin disease of most of skin diseases and certain systemic diseases
One of symptom.Especially with the growth at age, many elderly's sebaceous glands are degenerated, moisture-retaining capacity decline, in autumn and winter
It is had dry skin when arrival, will lead to serious pruitus.If excessively scratching for a long time, can cause affected part scratch innumerable, blood
Mark is in blocks, the coarse plump, pigmentation of sepage incrustation, with the passing of time illing skin, serious to lead to skin infection, fester, seriously
Influence health and normal life.
External use anti pruritic cosmetics mainly have floral water, menthol etc. at present, and itching-relieving action is mainly by being coated in skin
On make one generate cooling feeling, benumb cerebral cortex come what is realized, the itching-relieving action time is short and ineffective；External use anti pruritic drug is then
In the majority with hormone product, dependence is stronger, and side effect is big.
Poplar Chinese holly flower, i.e., Chinese white poplar male inflorescence, main active are flavone compounds, have antibacterial, anti-inflammatory, disease-resistant
Poison and other effects.Chinese white poplar is widely distributed, but poplar Chinese holly flower is not yet received as a kind of natural cheap, resourceful Chinese herbal medicine and fills
The utilization divided.Although there is document report poplar Chinese holly flower to have the effect for the treatment of pruitus and nettle rash, its user is not indicated
Formula.And document and relevant report in relation to poplar Chinese holly flower Anti-itch Products are also had no at present.
Summary of the invention
In view of the drawbacks of the prior art and insufficient, the present invention is using poplar Chinese holly flower and part moisturizing, antibacterial biological active matter
Matter is configured to itching-relieve skin-care mud, and itch skin is applied to after cleaning skin, can reach to the antipruritic of skin, antibacterial, disappear
Scorching and maintenance effect, and it is easy to use.
Specifically, the present invention relates to following technical schemes：
Firstly, being made of raw material from the following weight the invention discloses a kind of composition antipruritic for skin：Poplar Chinese holly
Spend 12~20 parts, 1~3 part of sodium alginate, 1~3 part of chitosan.
Preferably, the present composition is made of raw material from the following weight：Poplar Chinese holly spends 15 parts, and 1 part of sodium alginate, shell
1 part of glycan.
Secondly, the invention also discloses above-mentioned compositions to be used to prepare itching-relieve skin-care mud.
The preparation method of the itching-relieve skin-care mud, includes the following steps：
(1) dry Natural Poplar Chinese holly flower is chosen, pulverizer is put into and grinds, cross 80 meshes, obtain thin poplar Chinese holly pollen.
(2) chitosan and sodium alginate are added into the thin poplar Chinese holly pollen as obtained in step (1), three are mixed equal
It is even.
(3) mixed raw material is put into closed container, closed container is put into vertical pressure steam sterilizer sterilizing, is taken
It is cooled to room temperature after out.
(4) material vacuum after sterilization is packed, 6.8g raw material is put into each bag, every 10 bags are a box, pay attention to sealing
Kept dry.
In addition, the invention also discloses the application methods of above-mentioned itching-relieve skin-care mud.
Specifically, itching-relieve skin-care mud application method is as follows：
It (1) is 17 according to the mass ratio of itching-relieve skin-care mud and water:30g warm water is added in 75 ratio, each bag of raw material, sufficiently
Stir into the pureed mixture of fine uniform；
(2) skin especially to that the skin at itch occurs to clean with warm water, skin is may advantageously facilitate and preferably absorbs poplar
The antipruritic ingredient of Chinese holly flower antipruritic skin care preparation；
(3) the pureed mixture that step (1) obtains is applied to the itch skin after cleaning, to promote poplar Chinese holly to spend antipruritic shield
The antipruritic ingredient of skin mud penetrates into epidermal tissue, and release active material is to reach antipruritic, antibacterial, the effect of anti-inflammatory；
(4) after smearing uniformly, 10~15min better effect is moderately massaged with finger, finishes and is cleaned with clear water.
Pureed mixture after use can secondary use.Pureed mixture after smearing is collected, it is cooling after thermophilic digestion
Can be secondary for cleaning at pruitus to heating when thermophilic use, 2~5 parts of gleanings can also directly be poured into hot water, be used
In maniluvium, lavipeditum and whole body bathing.
Further, the invention also discloses the applications that above-mentioned composition is used to prepare antipruritic cosmetics.
Each raw material mechanism of action of the present invention：
Poplar Chinese holly flower, i.e. Chinese white poplar male inflorescence, main active are flavone compounds, including pinocembrin, Chrysin,
Pinostrobin etc. has antibacterial, anti-inflammatory, antiviral and other effects, is recorded in Chinese Pharmacopoeia in 1977.Flavone compound is a kind of
Low molecule plant component, be plant polyphenol metabolite, have anti-oxidant, antiallergy, remove free radical, blood pressure lowering, anti-inflammatory,
A variety of physiological activity effects such as antibacterial, spasmolysis, it is nontoxic, for staphylococcus aureus, Escherichia coli and withered grass bar
The inhibiting effect of bacterium is obvious.It is civil to commonly use its water decoction treatment chordapsus, bacillary dysentery etc..
Chitosan is the deacetylation product of chitin, is a kind of unique basic natural polysaccharides also known as chitosan, de- second
Acyl chitin is a kind of widely used bio-medical material.Chitosan has broad spectrum antibacterial, for Escherichia coli, withered grass
The common strain such as bacillus, staphylococcus aureus, Bacillus acidi lactici has apparent inhibiting effect, especially high deacetylized
Chitosan has stronger antibacterial action.Chitosan has the function of promoting blood clotting, anti-inflammatory, and can releive wound pain.Shell
Glycan can play the role of refrigerant and comfortable moisturizing when contacting wound skin, thus can be used as hemostasis and corium festers etc. outside
The adjuvant therapy medicaments of wound.In addition, chitosan can be also used for Wound filling substance, there is sterilization, promote wound healing, absorb
Wound exudate, be not easy syneresis and reduce scar generation the effects of.Chitosan has stronger water-retaining property and gel
The effect of change, also frequently as a kind of medicinal slow release agent.
Sodium alginate is a kind of polysaccharide carbohydrate extracted from the kelp or sargassum of brown algae, sodium alginate with
Its good biological degradability and biocompatibility are widely used in the fields such as chemistry, biology, medicine, food.Sodium alginate
Aqueous solution viscosity with higher, be usually used in thickener, stabilizer, emulsifier；Addition sodium alginate can be prevented in the product
Only occur the case where viscosity decline during high-temperature sterilization, while storage period can also be extended；Sodium alginate is a kind of natural
Vegetalitas wound repair material can be used to protect the surface of a wound with gel diaphragm or sponge material that it makes；Sodium alginate is a kind of
Auxiliary material with control-release function, is added sodium alginate in drug, since viscosity increases, can extend the release time of drug,
Absorption can also be slowed down, extend curative effect, mitigate side reaction.
The present invention achieves following beneficial effect：
(1) poplar Chinese holly of the invention flower itching-relieve skin-care mud, with, the pureed of texture lubrication fine and smooth in feel after warm water modulation stirring
Mixture.Directly smear it is clean after itch skin, poplar Chinese holly flower effective component can directly contact epidermis and play a role,
Skin at smearing is set to obtain antipruritic effect, affected part is refrigerant comfortable after smearing is cleaned, uncomfortable can alleviate because of itch at once caused by.
(2) when using poplar Chinese holly flower itching-relieve skin-care mud of the invention, the pureed mixture being modulated into warm water is conducive to promote
Into the dissolution of chitosan, the function that chitosan repairs wound is played, accelerates the healing of skin wound, while reaching antibacterial anti-inflammatory
Effect prevents scratching itch skin infection and causing from festering and other illnesss.Meanwhile the chitosan as auxiliary material, be conducive to original
The bonding of material is conducive to the fixed bonding of functional raw material poplar Chinese holly flower fine powder so that product generates lubrication, gentle texture one
It rises, concentrates and play antipruritic, antibacterial effect.In addition, water-retaining property effect of chitosan also has booster action for preserving moisture and protecting skin, apply
Water profit, soft and smooth, high resilience can be kept within a certain period of time with skin after the product.
(3) sodium alginate is safe and non-toxic non-stimulated as a kind of natural plant wound repair material, protects because of scratching
The surface of a wound of generation, while skin care mud viscosity is further improved, so that raw material poplar Chinese holly flower active constituent can slowly be released at smearing
It puts, interior for a long time after cleaning can have drug effect.Poplar Chinese holly flower itching-relieve skin-care mud of the invention is used for a long time, it can be achieved that apparent
Itching-relieving efficacies, duration of efficacy is long, and repairing effect is good.
(4) the skin care mud after use secondary can use after thermophilic digestion, so that raw material drug effect is fully used, economy side
Just.
(5) poplar Chinese holly of the invention flower itching-relieve skin-care mud raw material sources are extensive, low in cost, prepare strong operability, are convenient for
Production and processing.Product is sealed for storing for a long time in dry fine-powdered, is convenient for carrying and uses.
To sum up, the present invention is allowed to reasonably combined by the various composition of allotment above-mentioned composition, synergistic, so that this
The effect of invention gives full play to antipruritic, anti-inflammatory, antibacterial, restoration care skin.
Specific embodiment
Embodiment 1
(1) dry Natural Poplar Chinese holly flower 900g is chosen, pulverizer is put into and grinds, cross 80 meshes, obtain thin poplar Chinese holly pollen.
(2) chitosan 60g and sodium alginate 60g is added into the thin poplar Chinese holly pollen as obtained in step (1), and three is mixed
It closes uniform.
(3) mixed raw material is put into closed container, closed container is put into vertical pressure steam sterilizer sterilizing 15
~20min is cooled to room temperature after taking-up.
(4) material vacuum after sterilization is packed, 6.8g raw material is put into each bag, every 10 bags are a box, pay attention to sealing
Kept dry.
Embodiment 2
(1) dry Natural Poplar Chinese holly flower 600g is chosen, pulverizer is put into and grinds, cross 80 meshes, obtain thin poplar Chinese holly pollen.
(2) chitosan 50g and sodium alginate 50g is added into the thin poplar Chinese holly pollen as obtained in step (1), and three is mixed
It closes uniform.
(3) mixed raw material is put into closed container, closed container is put into vertical pressure steam sterilizer sterilizing 15
~20min is cooled to room temperature after taking-up.
(4) material vacuum after sterilization is packed, 6.8g raw material is put into each bag, every 10 bags are a box, pay attention to sealing
Kept dry.
Embodiment 3
(1) dry Natural Poplar Chinese holly flower 1000g is chosen, pulverizer is put into and grinds, cross 80 meshes, obtain thin poplar Chinese holly pollen.
(2) chitosan 150g and sodium alginate 150g is added into the thin poplar Chinese holly pollen as obtained in step (1), by three
It is uniformly mixed.
(3) mixed raw material is put into closed container, closed container is put into vertical pressure steam sterilizer sterilizing 15
~20min is cooled to room temperature after taking-up.
(4) material vacuum after sterilization is packed, 6.8g raw material is put into each bag, every 10 bags are a box, pay attention to sealing
Kept dry.
Embodiment 4
(1) according to mixed powder：Water quality ratio is 17:75 ratio, each bag of raw material are added 30g warm water, are sufficiently stirred into
The pureed mixture of fine uniform；
(2) skin especially to that the skin at itch occurs to clean with warm water, skin is may advantageously facilitate and preferably absorbs poplar
The antipruritic ingredient of Chinese holly flower antipruritic skin care preparation；
(3) the pureed mixture that step (1) obtains is applied to the itch skin after cleaning, to promote poplar Chinese holly to spend antipruritic shield
The antipruritic ingredient of skin mud penetrates into epidermal tissue, and release active material is to reach antipruritic, antibacterial, the effect of anti-inflammatory.
(4) after smearing uniformly, 10~15min is moderately massaged with finger, finishes and is cleaned with clear water.
Embodiment 5
Pureed mixture after smearing is collected, thermophilic digestion appropriate time, it can be secondary for cleaning skin after natural cooling
At skin itch.
Embodiment 6
Pureed mixture after smearing is collected, thermophilic digestion appropriate time, natural cooling.By the straight of 2~5 parts of gleanings
It connects and pours into hot water, be used for maniluvium, lavipeditum and whole body bathing.
Comparative example 1
(1) dry Natural Poplar Chinese holly flower 900g is chosen, pulverizer is put into and grinds, cross 80 meshes, obtain thin poplar Chinese holly pollen.
(2) chitin 60g and sodium alginate 60g is added into the thin poplar Chinese holly pollen as obtained in step (1), and three is mixed
It closes uniform.
(3) mixed raw material is put into closed container, closed container is put into vertical pressure steam sterilizer sterilizing 15
~20min is cooled to room temperature after taking-up.
(4) material vacuum after sterilization is packed, 6.8g raw material is put into each bag, every 10 bags are a box, pay attention to sealing
Kept dry.
By experimental verification, comparative example 1 replaces chitosan using chitin, and product moisture pick-up properties is deteriorated, influence effectively at
The performance divided, effect difference more of the present invention.
Comparative example 2
(1) dry Natural Poplar Chinese holly flower 900g is chosen, pulverizer is put into and grinds, cross 80 meshes, obtain thin poplar Chinese holly pollen.
(2) chitosan 60g and xanthan gum 60g is added into the thin poplar Chinese holly pollen as obtained in step (1), and three is mixed
Uniformly.
(3) mixed raw material is put into closed container, closed container is put into vertical pressure steam sterilizer sterilizing 15
~20min is cooled to room temperature after taking-up.
(4) material vacuum after sterilization is packed, 6.8g raw material is put into each bag, every 10 bags are a box, pay attention to sealing
Kept dry.
By experimental verification, comparative example 2 adds water since xanthan gum hydrophily is stronger using xanthan gum replacement sodium alginate
Skin care mud water absorbent surface expands to form micelle when use, influences the performance of effective component, and effect is good not as good as the present invention.
Experimental example
(1) general information
There are patient totally 30 of pruitus problem, wherein male 13, female 17, the ratio between men and women is 13:17, the age 20~
30 years old 12,31~50 years old 2,51 years old or more 16.
(2) judgment criteria
Reflection has pruitus problem.
(3) application method
It carries out by 4 mode of embodiment using 30 people are randomly divided into 3 groups, and every group of each 10 people is used continuously 2 weeks.
(4) effective evaluation standard
It is effective：Itch is substantially reduced or disappears, and secondary skin lesion subsides substantially, has clear improvement at itch skin；
Effectively：Itch mitigates, and secondary skin lesion makes moderate progress；
In vain：Itch does not mitigate without improvement, secondary skin lesion, and itch skin does not improve.
(5) result
In 30 test example effects, effective 20 people, effective 10 people, invalid 0 people.
The experimental example absolutely proves that the present invention has the effect for the treatment of and maintenance pruitus, and from starting to be applied to eventually not
See any adverse reaction.
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment
Limitation, those skilled in the art should understand that, based on the technical solutions of the present invention, those skilled in the art do not need
The various modifications or changes that can be made are made the creative labor still in protection scope of the present invention.
Claims (2)
1. a kind of itching-relieve skin-care mud, characterized in that be made of raw material from the following weight：Poplar Chinese holly spends 15 parts, and 1 part of sodium alginate,
1 part of chitosan；
Preparation method includes the following steps：
(1) dry Natural Poplar Chinese holly flower is chosen, pulverizer is put into and grinds, be sieved, obtain poplar Chinese holly pollen；
(2) chitosan and sodium alginate are added into the thin poplar Chinese holly pollen as obtained in step (1), and three is uniformly mixed；
(3) mixed raw material is put into closed container, closed container is put into vertical pressure steam sterilizer sterilizing, after taking-up
It is cooled to room temperature；
(4) material vacuum after sterilization is packed, pack；
In step (1), sieving sieve mesh number is 80 mesh.
2. itching-relieve skin-care mud as described in claim 1, characterized in that in step (4), it is put into 6.8g raw material in each bag, every 10
Bag is a box.
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| CN201610089142.9A CN105616296B (en) | 2016-02-17 | 2016-02-17 | A kind of poplar Chinese holly flower itching-relieve skin-care mud |
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| CN201610089142.9A CN105616296B (en) | 2016-02-17 | 2016-02-17 | A kind of poplar Chinese holly flower itching-relieve skin-care mud |
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| CN105616296B true CN105616296B (en) | 2018-11-20 |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106038399B (en) * | 2016-06-30 | 2018-11-13 | 山东师范大学 | A kind of foot film and preparation method thereof of the anti-chap deodorization of anti-inflammatory |
| CN106074258B (en) * | 2016-06-30 | 2018-09-11 | 山东师范大学 | A kind of anti-inflammatory anti-itch clean skin massage jelly |
| CN105997692B (en) * | 2016-06-30 | 2018-10-23 | 山东师范大学 | A kind of foot film of antipruritic anti-inflammatory moisturizing deodorization |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1823976A (en) * | 2005-12-16 | 2006-08-30 | 谢华 | External use medicine for relieving itch |
| CN1846666A (en) * | 2006-02-22 | 2006-10-18 | 黎秋萍 | Production process of fresh flower-algae bath agent |
| CN104306275A (en) * | 2014-09-04 | 2015-01-28 | 杨珍 | Cooling itch-relieving alga mint skin nourishing powder |
-
2016
- 2016-02-17 CN CN201610089142.9A patent/CN105616296B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1823976A (en) * | 2005-12-16 | 2006-08-30 | 谢华 | External use medicine for relieving itch |
| CN1846666A (en) * | 2006-02-22 | 2006-10-18 | 黎秋萍 | Production process of fresh flower-algae bath agent |
| CN104306275A (en) * | 2014-09-04 | 2015-01-28 | 杨珍 | Cooling itch-relieving alga mint skin nourishing powder |
Non-Patent Citations (1)
| Title |
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| 杨树花挥发性成分的GC/MS分析;何方奕等;《辽宁大学学报》;20000830;第27卷(第3期);第233-235页 * |
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