CN105616296A - Populus tomentosa itch-stopping skin-protecting paste - Google Patents
Populus tomentosa itch-stopping skin-protecting paste Download PDFInfo
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- CN105616296A CN105616296A CN201610089142.9A CN201610089142A CN105616296A CN 105616296 A CN105616296 A CN 105616296A CN 201610089142 A CN201610089142 A CN 201610089142A CN 105616296 A CN105616296 A CN 105616296A
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- skin
- chinese holly
- raw material
- itching
- poplar chinese
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/733—Alginic acid; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Abstract
The invention discloses Populus tomentosa itch-stopping skin-protecting paste. The paste is prepared from, by weight, 12-20 parts of Populus tomentosa, 1-3 parts of sodium alginate and 1-3 parts of chitosan. The paste is a pasty mixture which is exquisite in touch and smooth in texture after being mixed and stirred with warm water, and can play multiple roles in stopping itch, resisting bacteria, diminishing inflammation and protecting skin after being directly coated on itching skin after being cleaned. The paste is extensive in raw material source, low in cost, high in preparation operability, convenient to produce and process, is dry fine powder, can be stored for a long time after being sealed, is convenient to carry and use and has wide application prospect.
Description
Technical field
The invention belongs to cosmetic technical field, be specifically related to a kind of poplar Chinese holly flower itching-relieve skin-care mud.
Background technology
Skin pruritus is a kind of symptom of most of dermatosis and some systemic disease, is also one of symptom the most painful in dermatosis. Especially with the growth at age, many old people's sebaceous gland are degenerated, and moisture-retaining capacity declines, and the xerosis cutis when autumn and winter season arrives can cause serious skin pruritus. If excessively scratching for a long time, can causing affected part scratch innumerable, bloodstain is in blocks, and sepage is formed a scab, with the passing of time the coarse plumpness of illing skin, pigmentation, serious cause skin infection, fester, have a strong impact on healthy and orthobiosis.
Current external use anti pruritic cosmetics mainly have floral water, Mentholum etc., and its itching-relieving action produces cooling feeling mainly by being coated on skin to make people, and paralysis cerebral cortex realizes, and the itching-relieving action time is short and poor effect; External use anti pruritic medicine is then in the majority with hormones product, and dependency is relatively strong, and side effect is big.
Poplar Chinese holly flower, i.e. Cortex Populi Tomentosae staminate inflorescence, its main active is flavone compound, has the effects such as antibacterial, antiinflammatory, antiviral. Cortex Populi Tomentosae is widely distributed, but poplar Chinese holly flower is not yet fully utilized as a kind of natural Chinese herbal medicine cheap, resourceful. Although there being bibliographical information poplar Chinese holly flower to have the effect for the treatment of skin pruritus and urticaria, but do not indicate its occupation mode. And currently also have no the document about poplar Chinese holly flower Anti-itch Products and relevant report.
Summary of the invention
Defect and deficiency for prior art, the present invention adopts poplar Chinese holly flower and part moisturizing, antibacterial bioactive substance to be configured to itching-relieve skin-care mud, pruritus skin it is applied in, it is possible to reach antipruritic, antibacterial, the antiinflammatory to skin and maintenance effect after cleaning skin, and easy to use.
Concrete, the present invention relates to techniques below scheme:
First, the invention discloses a kind of compositions antipruritic for skin, be made up of the raw material of following weight portion: poplar Chinese holly spends 12��20 parts, sodium alginate 1��3 part, chitosan 1��3 part.
Preferably, the present composition, it is made up of the raw material of following weight portion: poplar Chinese holly spends 15 parts, sodium alginate 1 part, chitosan 1 part.
Secondly, the invention also discloses above-mentioned composition for preparing itching-relieve skin-care mud.
The preparation method of described itching-relieve skin-care mud, comprises the following steps:
(1) choose dry Natural Poplar Chinese holly flower, put into pulverizer and grind, cross 80 mesh sieves, obtain thin poplar Chinese holly pollen.
(2) to by the thin poplar Chinese holly pollen obtained in step (1) adds chitosan and sodium alginate, by three's mix homogeneously.
(3) mixed raw material is put into hermetic container, hermetic container is put into vertical pressure steam sterilizer sterilizing, after taking-up, be cooled to room temperature.
(4) by the material vacuum packaging after sterilization, putting into 6.8g raw material in each bag, every 10 bags is a box, notices that hermetically drying preserves.
Additionally, the invention also discloses the using method of above-mentioned itching-relieve skin-care mud.
Concrete, itching-relieve skin-care mud using method is as follows:
(1) according to the ratio that mass ratio is 17:75 of itching-relieve skin-care mud Yu water, each bag of raw material adds 30g warm water, is sufficiently stirred for into the pureed mixture of fine uniform;
(2) especially occur the skin at pruritus place to clean skin with warm water, may advantageously facilitate skin and better absorb the antipruritic composition of poplar Chinese holly flower antipruritic skin care preparation;
(3) the pureed mixture that step (1) obtains is applied in the pruritus skin after cleaning, and to promote that the antipruritic composition of poplar Chinese holly flower itching-relieve skin-care mud penetrates into epidermal tissue, release active substance is antipruritic to reach, antibacterial, the effect of antiinflammatory;
(4) smearing after uniformly, massage 10��15min effect more preferably by finger appropriateness, complete clear water is cleaned.
Pureed mixture after using can utilize by secondary. Pureed mixture after smearing is collected, be cooled to after high temperature steaming when thermophilic uses heating can secondary for cleaning skin pruritus place, it is possible to 2��5 parts of gleanings are directly poured in hot water, for maniluvium, foot bath and whole body bathing.
Further, the invention also discloses above-mentioned composition for preparing the application of antipruritic cosmetics.
The each raw material mechanism of action of the present invention:
Poplar Chinese holly flower, i.e. Cortex Populi Tomentosae staminate inflorescence, its main active is flavone compound, including pinocembrin, chrysin, pinostrobin etc., has the effects such as antibacterial, antiinflammatory, antiviral, is recorded in Chinese Pharmacopoeia in 1977. Flavone compound is a class low molecule plant component, for plant Polyphenols metabolite, there is the multiple physiologically active effects such as antioxidation, antiallergic, scavenging free radicals, blood pressure lowering, antiinflammatory, antibacterial, spasmolytic, nontoxic, the inhibitory action for staphylococcus aureus, Escherichia coli and bacillus subtilis is obvious. Conventional its water decoction treatment acute enteritis, bacillary dysentery etc. among the people.
Chitosan is the deacetylation product of chitin, is a kind of unique basic natural polysaccharides, has another name called chitosan, chitosan, be a kind of widely used bio-medical material. Chitosan has broad spectrum antibacterial, has obvious inhibitory action for common strains such as escherichia coli, bacillus subtilis, staphylococcus aureus, lactobacilluss, and especially high deacetylized chitosan has higher antibacterial action. Chitosan has the effect promoting blood coagulation, antiinflammatory, wound pain of can releiving. Refrigerant and comfortable skin moistening effect can be played during chitosan contact wound skin, thus can be used as hemostasis and corium such as festers at the adjuvant therapy medicaments of wound. Additionally, chitosan can be also used for Wound filling material, there is sterilization, promote that the generation etc. of wound healing, absorption Wound exudate, not easily syneresis and minimizing cicatrix acts on. Chitosan has the effect of stronger water-retaining property and gelation, also frequently as a kind of medicinal slow release agent.
Sodium alginate is a kind of polysaccharide carbohydrate extracted the Thallus Laminariae (Thallus Eckloniae) from Brown algae or Alga Sgrgassi Enerves, and sodium alginate, with its good biological degradability and biocompatibility, is widely used in the fields such as chemistry, biology, medicine, food. The aqueous solution of sodium alginate has higher viscosity, is usually used in thickening agent, stabilizer, emulsifying agent; Add the situation that sodium alginate is prevented from occurring viscosity degradation in high-temperature sterilization process in the product, storage period can also be extended simultaneously; Sodium alginate is a kind of natural plant repair in trauma material, with the gel diaphragm of its making or sponge material, can be used to protect wound surface; Sodium alginate is a kind of adjuvant with control-release function, adds sodium alginate in medicine, owing to viscosity increases, it is possible to extend the release time of medicine, absorption of also can slowing down, extends curative effect, alleviates side reaction.
The present invention achieves following beneficial effect:
(1) the poplar Chinese holly flower itching-relieve skin-care mud of the present invention, with fine and smooth in feel after warm water modulation stirring, the pureed mixture of texture lubrication. Directly smear cleaning clean after pruritus skin, poplar Chinese holly flower effective ingredient can directly contact epidermis and play a role, and makes the place of smearing skin obtain antipruritic effect, smears that to clean rear affected part refrigerant comfortable, can alleviate the discomfort because pruritus causes at once.
(2) when using the poplar Chinese holly flower itching-relieve skin-care mud of the present invention, the pureed mixture being modulated into warm water, may advantageously facilitate the dissolving of chitosan, play chitosan and repair the function of wound, accelerate the healing of skin wound, reach effect of anti-inflammation, it is prevented that scratch pruritus skin infection and cause and fester and other diseases simultaneously. Meanwhile, as the chitosan of adjuvant, be conducive to the bonding of raw material so that product produces lubrication, gentle texture, be conducive to sticking together fixing for functional raw material poplar Chinese holly flower fine powder, concentrate and play antipruritic, antibacterial effect. It addition, water-retaining property effect of chitosan also has assosting effect for preserving moisture and protecting skin, after this product of application, skin can keep water profit, soft and smooth, high resilience within a certain period of time.
(3) sodium alginate is as a kind of natural plant repair in trauma material; safety non-toxic is non-stimulated; protect because of the wound surface produced of scratching; further increase skin protection mud viscosity simultaneously; make raw material poplar Chinese holly flower active component can smear place's slow releasing, it is possible in long-time after cleaning, to have drug effect. The poplar Chinese holly flower itching-relieve skin-care mud of the life-time service present invention, it may be achieved significantly itching-relieving efficacies, duration of efficacy is long, and repairing effect is good.
(4) the skin protection mud after using can use by secondary after high temperature steaming, makes raw material drug effect be fully used, economical convenient.
(5) the poplar Chinese holly flower itching-relieve skin-care mud raw material sources of the present invention are extensive, with low cost, prepare workable, it is simple to production and processing. Product, in dry fine-powdered, seals preservation and is available for long storage periods, be convenient for carrying and use.
To sum up, the present invention is by allocating the various compositions of above-mentioned composition, so as to reasonably combined, and Synergistic so that the present invention gives full play to effect of antipruritic, antiinflammatory, antibacterial, restoration care skin.
Detailed description of the invention
Embodiment 1
(1) choose dry Natural Poplar Chinese holly flower 900g, put into pulverizer and grind, cross 80 mesh sieves, obtain thin poplar Chinese holly pollen.
(2) to by the thin poplar Chinese holly pollen obtained in step (1) adds chitosan 60g and sodium alginate 60g, by three's mix homogeneously.
(3) mixed raw material is put into hermetic container, hermetic container is put into vertical pressure steam sterilizer sterilizing 15��20min, after taking-up, is cooled to room temperature.
(4) by the material vacuum packaging after sterilization, putting into 6.8g raw material in each bag, every 10 bags is a box, notices that hermetically drying preserves.
Embodiment 2
(1) choose dry Natural Poplar Chinese holly flower 600g, put into pulverizer and grind, cross 80 mesh sieves, obtain thin poplar Chinese holly pollen.
(2) to by the thin poplar Chinese holly pollen obtained in step (1) adds chitosan 50g and sodium alginate 50g, by three's mix homogeneously.
(3) mixed raw material is put into hermetic container, hermetic container is put into vertical pressure steam sterilizer sterilizing 15��20min, after taking-up, is cooled to room temperature.
(4) by the material vacuum packaging after sterilization, putting into 6.8g raw material in each bag, every 10 bags is a box, notices that hermetically drying preserves.
Embodiment 3
(1) choose dry Natural Poplar Chinese holly flower 1000g, put into pulverizer and grind, cross 80 mesh sieves, obtain thin poplar Chinese holly pollen.
(2) to by the thin poplar Chinese holly pollen obtained in step (1) adds chitosan 150g and sodium alginate 150g, by three's mix homogeneously.
(3) mixed raw material is put into hermetic container, hermetic container is put into vertical pressure steam sterilizer sterilizing 15��20min, after taking-up, is cooled to room temperature.
(4) by the material vacuum packaging after sterilization, putting into 6.8g raw material in each bag, every 10 bags is a box, notices that hermetically drying preserves.
Embodiment 4
(1) according to mixed powder: water quality is than the ratio for 17:75, and each bag of raw material adds 30g warm water, is sufficiently stirred for into the pureed mixture of fine uniform;
(2) especially occur the skin at pruritus place to clean skin with warm water, may advantageously facilitate skin and better absorb the antipruritic composition of poplar Chinese holly flower antipruritic skin care preparation;
(3) the pureed mixture that step (1) obtains is applied in the pruritus skin after cleaning, and to promote that the antipruritic composition of poplar Chinese holly flower itching-relieve skin-care mud penetrates into epidermal tissue, release active substance is antipruritic to reach, antibacterial, the effect of antiinflammatory.
(4) smearing after uniformly, massage 10��15min by finger appropriateness, complete clear water is cleaned.
Embodiment 5
Pureed mixture after smearing is collected, high temperature steaming appropriate time, can be used for cleaning skin pruritus place by secondary after natural cooling.
Embodiment 6
Pureed mixture after smearing is collected, high temperature steaming appropriate time, natural cooling. 2��5 parts of gleanings are directly poured in hot water, for maniluvium, foot bath and whole body bathing.
Comparative example 1
(1) choose dry Natural Poplar Chinese holly flower 900g, put into pulverizer and grind, cross 80 mesh sieves, obtain thin poplar Chinese holly pollen.
(2) to by the thin poplar Chinese holly pollen obtained in step (1) adds chitin 60g and sodium alginate 60g, by three's mix homogeneously.
(3) mixed raw material is put into hermetic container, hermetic container is put into vertical pressure steam sterilizer sterilizing 15��20min, after taking-up, is cooled to room temperature.
(4) by the material vacuum packaging after sterilization, putting into 6.8g raw material in each bag, every 10 bags is a box, notices that hermetically drying preserves.
Through experimental verification, comparative example 1 adopts chitin to replace chitosan, and product moisture pick-up properties is deteriorated, and affects the performance of effective ingredient, and the relatively present invention is poor for effect.
Comparative example 2
(1) choose dry Natural Poplar Chinese holly flower 900g, put into pulverizer and grind, cross 80 mesh sieves, obtain thin poplar Chinese holly pollen.
(2) to by the thin poplar Chinese holly pollen obtained in step (1) adds chitosan 60g and xanthan gum 60g, by three's mix homogeneously.
(3) mixed raw material is put into hermetic container, hermetic container is put into vertical pressure steam sterilizer sterilizing 15��20min, after taking-up, is cooled to room temperature.
(4) by the material vacuum packaging after sterilization, putting into 6.8g raw material in each bag, every 10 bags is a box, notices that hermetically drying preserves.
Through experimental verification, comparative example 2 adopts xanthan gum to replace sodium alginate, and owing to xanthan gum hydrophilic is relatively strong, skin protection mud water absorbent surface when using that adds water expands and forms micelle, affects the performance of effective ingredient, and effect is good not as the present invention.
Experimental example
(1) physical data
Having patient's totally 30 example of skin pruritus problem, wherein male 13 examples, female 17 example, the ratio of men and women is 13:17,20��30 years old age, 12 examples, 31��50 years old 2 example, more than 51 years old 16 examples.
(2) criterion
All reflection has skin pruritus problem.
(3) using method
Using by embodiment 4 mode, 30 people are randomly divided into 3 groups, often organize each 10 people, use 2 weeks continuously.
(4) effective evaluation standard
Effective: pruritus substantially alleviates or disappears, secondary skin lesion disappears substantially, and pruritus skin place has clear improvement;
Effective: pruritus alleviates, secondary skin lesion makes moderate progress;
Invalid: pruritus is without improvement, and secondary skin lesion does not alleviate, and pruritus skin does not improve.
(5) result
In 30 example test example effects, effective 20 people, effective 10 people, invalid 0 people.
This experimental example absolutely proves that the present invention possesses effect for the treatment of and maintenance skin pruritus, and has no any untoward reaction eventually from starting to be applied to.
Above-described embodiment is the present invention preferably embodiment; but embodiments of the present invention are also not restricted to the described embodiments; one of ordinary skill in the art should be understood that; on the basis of technical scheme, those skilled in the art need not pay various amendments or deformation that creative work can make still in protection scope of the present invention.
Claims (10)
1. one kind is used for the compositions that skin is antipruritic, it is characterised in that be made up of the raw material of following weight portion: poplar Chinese holly spends 12��20 parts, sodium alginate 1��3 part, chitosan 1��3 part.
2. a kind of compositions antipruritic for skin as claimed in claim 1, is characterized in that, be made up of the raw material of following weight portion: poplar Chinese holly spends 15 parts, sodium alginate 1 part, chitosan 1 part.
3. an itching-relieve skin-care mud, is characterized in that, adopts compositions described in any one of claim 1-2 to prepare.
4. the preparation method of itching-relieve skin-care mud as claimed in claim 3, is characterized in that, comprise the following steps:
(1) choose dry Natural Poplar Chinese holly flower, put into pulverizer and grind, sieve, obtain poplar Chinese holly pollen;
(2) to by the thin poplar Chinese holly pollen obtained in step (1) adds chitosan and sodium alginate, by three's mix homogeneously;
(3) mixed raw material is put into hermetic container, hermetic container is put into vertical pressure steam sterilizer sterilizing, after taking-up, be cooled to room temperature;
(4) by the material vacuum packaging after sterilization, pack.
5. preparation method as claimed in claim 4, is characterized in that, in step (1), sieve number of sieving is 80 orders.
6. preparation method as claimed in claim 4, is characterized in that, in step (4), putting into 6.8g raw material in each bag, every 10 bags is a box.
7. the using method of itching-relieve skin-care mud as claimed in claim 3, is characterized in that, comprise the following steps:
(1) in itching-relieve skin-care mud: the mass ratio of water is the ratio of 17:75, it is sufficiently stirred for into the pureed mixture of fine uniform;
(2) skin at pruritus place is especially occurred to clean skin with warm water;
(3) the pureed mixture that step (1) obtains is applied in the pruritus skin after cleaning;
(4) smear after uniformly, press...with one's finger and rub, clean with clear water.
8. the using method described in claim 7, is characterized in that, is warm water with water described in step (1).
9. the using method described in claim 7, is characterized in that, step (4) is smeared after uniformly, and press...with one's finger the 10��15min that rubs.
10. the compositions described in any one of claim 1-2 is preparing the application of antipruritic cosmetics.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610089142.9A CN105616296B (en) | 2016-02-17 | 2016-02-17 | A kind of poplar Chinese holly flower itching-relieve skin-care mud |
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| CN201610089142.9A CN105616296B (en) | 2016-02-17 | 2016-02-17 | A kind of poplar Chinese holly flower itching-relieve skin-care mud |
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| CN105616296B CN105616296B (en) | 2018-11-20 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105997692A (en) * | 2016-06-30 | 2016-10-12 | 山东师范大学 | Foot mask capable of relieving itching, diminishing inflammation, preserving moisture and removing odour |
| CN106038399A (en) * | 2016-06-30 | 2016-10-26 | 山东师范大学 | Foot mask for diminishing inflammation, preventing chap and removing odor and preparation method thereof |
| CN106074258A (en) * | 2016-06-30 | 2016-11-09 | 山东师范大学 | A kind of anti-inflammatory anti-itch clean skin massage is frozen |
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| CN1846666A (en) * | 2006-02-22 | 2006-10-18 | 黎秋萍 | Production process of fresh flower-algae bath agent |
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| CN1823976A (en) * | 2005-12-16 | 2006-08-30 | 谢华 | External use medicine for relieving itch |
| CN1846666A (en) * | 2006-02-22 | 2006-10-18 | 黎秋萍 | Production process of fresh flower-algae bath agent |
| CN104306275A (en) * | 2014-09-04 | 2015-01-28 | 杨珍 | Cooling itch-relieving alga mint skin nourishing powder |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105997692A (en) * | 2016-06-30 | 2016-10-12 | 山东师范大学 | Foot mask capable of relieving itching, diminishing inflammation, preserving moisture and removing odour |
| CN106038399A (en) * | 2016-06-30 | 2016-10-26 | 山东师范大学 | Foot mask for diminishing inflammation, preventing chap and removing odor and preparation method thereof |
| CN106074258A (en) * | 2016-06-30 | 2016-11-09 | 山东师范大学 | A kind of anti-inflammatory anti-itch clean skin massage is frozen |
| CN106074258B (en) * | 2016-06-30 | 2018-09-11 | 山东师范大学 | A kind of anti-inflammatory anti-itch clean skin massage jelly |
| CN105997692B (en) * | 2016-06-30 | 2018-10-23 | 山东师范大学 | A kind of foot film of antipruritic anti-inflammatory moisturizing deodorization |
| CN106038399B (en) * | 2016-06-30 | 2018-11-13 | 山东师范大学 | A kind of foot film and preparation method thereof of the anti-chap deodorization of anti-inflammatory |
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| Publication number | Publication date |
|---|---|
| CN105616296B (en) | 2018-11-20 |
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