CN107137682A - A kind of Chinese medicine composition for treating apoplexy and application - Google Patents

A kind of Chinese medicine composition for treating apoplexy and application Download PDF

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Publication number
CN107137682A
CN107137682A CN201710360144.1A CN201710360144A CN107137682A CN 107137682 A CN107137682 A CN 107137682A CN 201710360144 A CN201710360144 A CN 201710360144A CN 107137682 A CN107137682 A CN 107137682A
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CN
China
Prior art keywords
medicine
apoplexy
parts
angelicae sinensis
jute
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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CN201710360144.1A
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Chinese (zh)
Inventor
谢雪玲
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Foshan Lingzhuo Technology Co Ltd
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Foshan Lingzhuo Technology Co Ltd
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Priority to CN201710360144.1A priority Critical patent/CN107137682A/en
Publication of CN107137682A publication Critical patent/CN107137682A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of Chinese medicine composition for treating apoplexy and its application, described pharmaceutical composition with following raw materials by being made:Jute, gypsum, osmanthus heart, rhizoma zingiberis, Ligusticum wallichii, Radix Angelicae Sinensis, radix scutellariae, almond.The present invention specify that the formula and preparation method of medicine, overcome the deficiency of existing treatment apoplexy medicine, and function admirable, the therapeutic effect of Patients with Apoplexy After is good.

Description

A kind of Chinese medicine composition for treating apoplexy and application
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of important drug composition for treating apoplexy and application.
Background technology
Apoplexy is the common refractory disease for seriously endangering human health and life security, usually brings three inclined symptoms: Hemiplegia (side myodynamia decline, activity it is unfavorable or completely it is stiff), hemidysesthesia (it is cold and hot do not know, pain not Feel), hemianopsia (defect of visual field, blurred vision), and with dysphonia or motor aphasia.In a big way or after multiple relapse Spirit and dysnoesia (personality change, One's spirits are drooping, emotional, dementia) can be left by losing the symptom of disease.Therefore to the pre- of apoplexy The anti-research with treatment causes the very big concern of people always.
Chinese invention patent 101843851B is related to the preparation of anti-hypertension apoplexy medicine, it is desirable to provide a kind of anti-hypertension Dendrobium officinale nimodipine combination medicine of apoplexy and preparation method thereof.The dendrobium candidum Nimodipine of the anti-hypertension apoplexy is closed With medicine, effective component includes the mass ratio of dendrobium officinale aqueous extract and Nimodipine, dendrobium officinale aqueous extract and Nimodipine For 1.0~4.0: 0.12~0.24.The invention is additionally provided in the medicinal extract based on the medicine, granule, tablet, capsule, medicine Mesosome and preparation method thereof.The invention, which discloses the use of combination with medication and dendrobium candidum or the independent of Nimodipine any one, to be made With comparing, not only can be faster reduce blood pressure is better able to the reduction death rate, extension life span.Such as spy The medicine for determining purposes is used, and can relax lasting reduction hyperpietic's blood pressure, delays hypertensive cerebral vascular infringement progress, To mankind's preventing hypertension apoplexy, the disabling of reduction high blood pressure, fatal rate are significant.
Chinese invention patent 102614234B discloses a kind of Aggrenox compositions and tablet and preparation method thereof.Side Method:Crude drug Ligusticum wallichii and Radix Angelicae Sinensis are added into 10 times of 70% ethanol of amount for the first time, extractor is placed in, keeps 70-100 DEG C of extraction 2 small When, extract solution is filtered out, the first extract solution is obtained, solid filter residue is stand-by.8 times of 70% ethanol of amount are added in solid filter residue, are placed in Extractor, is kept for 70-100 DEG C extract 1.5 hours, filters out extract solution, filter out extract solution, obtains the second extract solution and solid filter Slag.Mixed extract, under the conditions of temperature is 60-70 DEG C, no alcohol taste is concentrated under reduced pressure into mixed liquor, obtains extracting concentration Thing, the relative density of concentrate is 1.10~1.30, and its Midst density is measured at 60 DEG C;Add what is crushed in extraction concentrat Natural borneol dissolves, and produces Pharmaceutical composition;The weight proportion of medicinal material used is:10~50 parts of Ligusticum wallichii, Radix Angelicae Sinensis 50~10 part, day Right 1~10 part of borneol.Obtained composition has obvious repair to apoplexy, the impaired of cranial nerve function.
Chinese invention patent 104435318B discloses a kind of extraction for treating hemorrhagic stroke Chinese medical extract components group Method and its application.Rheum officinale, the root bark of tree peony, the radix paeoniae rubrathe, the dried rhizome of rehmannia, pseudo-ginseng add water to cook extraction, extract solution according to a certain weight ratio, after crushing After being extracted with dichloromethane, water layer uses extracting n-butyl alcohol again, is Chinese medical extract components group after butanol extraction liquid recovery is dry.Should Chinese medical extract is analyzed by Chinese herbaceous peony glycoside, tannin class, Paeonol glycoside, Anthraquinones, stilbene class, saponins and cyclenes with HPLC-MS 33 composition compositions of ether terpene glycoside, can significantly reduce male spontaneously hypertensive rat neuronspecific enolase, S- 100 β albumen, IL-1, TNF-α, plasma fibrinogen level, available for the purposes for preparing treatment hemorrhagic stroke medicine.
However, the effect of the medicine of Current therapeutic apoplexy is not good.According to statistics, the annual disease for occurring headstroke of China People is just up to 2,000,000.Existing survival stroke patient 7,000,000, wherein the different degrees of disability of 4,500,000 patients and life be unable to from Reason, disability rate is up to 75%.Chinese annual stroke patient dead 1,200,000.
The content of the invention
Goal of the invention:In order to improve the therapeutic effect of stroke patient, the invention provides a kind of Chinese medicine group for treating apoplexy Compound.
To achieve the above object, by a large amount of practices of inventor, medicine of the invention is made up of following raw materials:
Jute, gypsum, osmanthus heart, rhizoma zingiberis, Ligusticum wallichii, Radix Angelicae Sinensis, radix scutellariae, almond.
Preferably, to being limited below the work by weight ratio of each component:
1 part of Radix Angelicae Sinensis, 1 ~ 1.5 part of radix scutellariae, osmanthus heart, rhizoma zingiberis, 2 ~ 3 parts of Ligusticum wallichii, gypsum, 3 ~ 4 parts of almond, 6 ~ 7 parts of jute.
Further preferably, medicine of the invention is made up by weight of following raw materials according:
Radix Angelicae Sinensis, 1 part of radix scutellariae, osmanthus heart, rhizoma zingiberis, 2 parts of Ligusticum wallichii, gypsum, 3 parts of almond, 6 parts of jute.
The formulation of pharmaceutical composition of the present invention can be the medical science such as decoction, pill, powder, tablet, capsule, granule Upper acceptable formulation, preparation is processed by existing common process.
Present invention additionally comprises said medicine for treating the application in apoplexy.
The pharmaceutical formulation of the present invention, for the pathogenesis of apoplexy, has the effect of replenishing and activating blood from Radix Angelicae Sinensis;Ligusticum wallichii has There are promoting qi circulation and relieving pain, warming kidney and enhancing yang, the broken product effect of stagnation resolvation;Rhizoma zingiberis has warming spleen and stomach for dispelling cold, Back to Yang Tongmai, the effect of Wenfei of drink;It is yellow A kind of reed mentioned in ancient books has the effect of heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, hypotensive;Zhu Fang is shared, and can reach the purpose treated both principal and secondary aspect of disease, right The symptoms such as miocardial infarction, cerebral infarction, apoplexy, heart rhythm disorders, acute cerebral hemorrhage disease have good curative effect.
Embodiment
The present invention is further illustrated with reference to embodiment.
Radix Angelicae Sinensis, 100 grams of radix scutellariae, osmanthus heart, rhizoma zingiberis, 200 grams of Ligusticum wallichii, gypsum, 300 grams of almond, 600 grams of jute are taken, it is standby;Will Jute is put into 4 liters of water, is boiled, filtering, is added other all medicinal materials, is boiled, obtain decoction.

Claims (5)

1. a kind of medicine, it is characterised in that the medicine is by jute, gypsum, osmanthus heart, rhizoma zingiberis, Ligusticum wallichii, Radix Angelicae Sinensis, radix scutellariae, almond group Into.
2. a kind of medicine according to claim 1, it is characterised in that each component of described medicine example in mass ratio is matched It is as follows:1 part of Radix Angelicae Sinensis, 1 ~ 1.5 part of radix scutellariae, osmanthus heart, rhizoma zingiberis, each 2 ~ 3 parts of Ligusticum wallichii, gypsum, each 3 ~ 4 parts of almond, 6 ~ 7 parts of jute.
3. a kind of medicine according to claim 2, it is characterised in that each component of described medicine example in mass ratio is matched It is as follows:Radix Angelicae Sinensis, 1 part of radix scutellariae, osmanthus heart, rhizoma zingiberis, each 2 parts of Ligusticum wallichii, gypsum, each 3 parts of almond, 6 parts of jute.
4. a kind of medicine according to claim 1, it is characterised in that the formulation of described medicine can be decoction, pill, The medically acceptable formulation such as powder, tablet, capsule, granule.
5. a kind of medicine according to claim 1-4, it is characterised in that described medicinal application is in treatment apoplexy.
CN201710360144.1A 2017-05-20 2017-05-20 A kind of Chinese medicine composition for treating apoplexy and application Pending CN107137682A (en)

Priority Applications (1)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108187018A (en) * 2018-03-15 2018-06-22 天津白大夫健康管理有限公司 One kind prolongs raw granular recipe

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102895632A (en) * 2011-07-29 2013-01-30 苏州知微堂生物科技有限公司 Preparation technology and production method for integrated new formulation of life-prolonging decotion

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102895632A (en) * 2011-07-29 2013-01-30 苏州知微堂生物科技有限公司 Preparation technology and production method for integrated new formulation of life-prolonging decotion

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
吴积海: "脑中风从肺论治", 《河南中医学院学报》 *
周艳艳: "《产科病方剂证治》", 28 February 2014 *
王红: "用大麻治疗中风", 《药物与人》 *
陈立峰: "续命汤颗粒剂治疗中风31例临床观察", 《湖南中医杂志》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108187018A (en) * 2018-03-15 2018-06-22 天津白大夫健康管理有限公司 One kind prolongs raw granular recipe

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Application publication date: 20170908

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