CN101618131A - Chinese medicinal compound preparation for treating coronary heart disease and angina - Google Patents
Chinese medicinal compound preparation for treating coronary heart disease and angina Download PDFInfo
- Publication number
- CN101618131A CN101618131A CN 200810115978 CN200810115978A CN101618131A CN 101618131 A CN101618131 A CN 101618131A CN 200810115978 CN200810115978 CN 200810115978 CN 200810115978 A CN200810115978 A CN 200810115978A CN 101618131 A CN101618131 A CN 101618131A
- Authority
- CN
- China
- Prior art keywords
- radix
- rhizoma
- parts
- chinese medicinal
- heart disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses Chinese medicinal compound preparation for treating coronary heart disease and angina. The Chinese medicinal compound preparation is granular formulation, capsule formulation and tablet formulation which are prepared from the following 12 kinds of Chinese medicinal materials in certain proportion by weight: danshen root, golden thread, membranous milkvetch root, kudzuvine root, szechuan lovage rhizome, rhodiola rosea, yanhusuo, ginkgo leaf, Chinese honeylocust spine, safflower, nutgrass galingale rhizome and red paeony root. The compound preparation has effects of activating blood circulation to dissipate blood stasis, tonifying qi, relieving pain and nourishing kidney-Yin, and can be used for treating the coronary heart disease, the angina and symptoms of chest distress, chest pain, cardiopalmus, dizziness, insomnia, tinnitus, lassitude in the loin and knees and the like. In addition, the medicament of the compound preparation has the characteristics of high bioavailability and obvious curative effect.
Description
Technical field
The invention belongs to the Chinese medicine preparation technical field, relate to a kind of compound Chinese medicinal preparation, be specifically related to a kind of treatment coronary heart disease, anginal compound Chinese medicinal preparation, and its preparation method has been done correlational study.
Technical background
Coronary heart disease is a kind of myocardial ischemia-anoxemia that is caused by coronary artery organic stenosis or obstruction or the heart disease of myocardial necrosis, also claims ischemic heart desease.Our the coronary heart disease majority said is that tremulous pulse organic stenosis or obstruction cause at ordinary times, and the shape atherosclerotic heart disease wins again.Due to its coronary stricture polyphyly fatty material was piled up along blood vessel, this process was called arteriosclerosis.Arteriosclerosis develops into to a certain degree, and coronary stricture increases the weight of gradually, and restriction flows into the blood flow of cardiac muscle.Heart can not get enough oxygen and supplies with, and the chest discomfort will take place, i.e. angina pectoris.The angina pectoris attacks performance of different people differs.Majority describe that it is " pressure in chest ", " vexed bloated sense " " sense of feeling oppressed ", and part patient's sensation is diffused to bilateral shoulder, back, cervical region, bottleneck throat, has a rest or the alleviation of buccal nitroglycerin.
Angina pectoris shows as retrosternal squeezing sense, and tangible anxiety is followed in vexed bloated sense, continue 3～5 minutes, often diffuse to the left side arm, shoulder, lower jaw, bottleneck throat, the back also can emit to right arm. and can involve these positions sometimes and do not influence the breastbone back zone. firmly, excited, catch cold, that shows effect under the increase myocardial oxygen consumption situations such as heavy meal is called effort angina, has a rest and containing nitroglycerin is alleviated.Angina pectoris sometimes is not true to type, and it is tight to show as gas, faint, and weakness, belch is especially the old people.The frequency and the order of severity according to outbreak are divided into stable type and unstable angina pectoris.Stable angina pectoris refers to outbreak above effort angina in January, its position of showing effect, and frequency, the order of severity, the persistent period, labour's size of luring outbreak into, the lenitive nitroglycerin consumption of energy is basicly stable.Unstable angina pectoris refers to makes original stable angina pectoris seizure frequency, and the persistent period, the order of severity increases, the angina pectoris that shows effect during the perhaps effort angina of new outbreak, or tranquillization.Unstable angina pectoris is the omen of acute myocardial infarction, so in case find medication immediately or go to see a doctor.
Coronary heart disease is the commonly encountered diseases and the frequently-occurring disease of middle-aged and elderly people, is in the people of this age level, in daily life, if following situation will in time be sought medical advice, finds coronary heart disease as early as possible.
Summary of the invention
The object of the invention is to provide a kind of treatment coronary heart disease, anginal compound Chinese medicinal preparation, comprises its prescription and preparation method.
Be achieved through the following technical solutions order of the present invention:
1, the present invention is made by the following weight proportion raw material:
Radix Salviae Miltiorrhizae 30-90 part Rhizoma Coptidis 50-100 part Radix Astragali 30-90 part
Radix Puerariae 60-120 part Rhizoma Chuanxiong 30-90 part Radix Rhodiolae 60-120 part
Rhizoma Corydalis 50-100 part Folium Ginkgo 20-60 part Spina Gleditsiae 30-90 part
Flos Carthami 50-100 part Rhizoma Cyperi 20-60 part Radix Paeoniae Rubra 50-100 part
2, best each the raw material weight proportioning of prescription of the present invention is:
65 parts of 80 parts of Radixs Astragali of 65 portions of Rhizoma Coptidis of Radix Salviae Miltiorrhizae
110 parts of 65 parts of Radix Rhodiolaes of 110 parts of Rhizoma Chuanxiongs of Radix Puerariae
65 parts of 45 parts of Spina Gleditsiaes of 80 parts of Folium Ginkgos of Rhizoma Corydalis
80 parts of 45 parts of Radix Paeoniae Rubra of 80 portions of Rhizoma Cyperis of Flos Carthami
3, preparation method:
(1) get Rhizoma Chuanxiong, Flos Carthami, Rhizoma Cyperi, mix, vapor distillation extracts volatile oil, and is standby;
(2) get Radix Salviae Miltiorrhizae, Rhizoma Coptidis, Rhizoma Corydalis, extract 2～4 times with 10 times of amount 70% alcohol heating reflux, each 1.5 hours, collect and merge alcohol extract, filter, decompression filtrate recycling ethanol and concentrate ethanol extract extractum, standby;
(3) with Six-elements such as the Radix Astragali, Radix Puerariae, Radix Rhodiolaes, add 10 times of water gagings and decoct 4 times, each 1 hour, the gradation of decocting liquid filtered, filtrate decompression concentrate water extract extractum, standby;
(4) ethanol extract extractum and water extract extractum are merged mixing, drying is ground into fine powder, sieves, add starch or other preparations shaping adjuvants, mixing is granulated, put the spray of cold back and add volatile oil, make granule, capsule, tablet (plain sheet, Film coated tablets or coated tablet), promptly.
The invention discloses a kind of treatment coronary heart disease, anginal compound Chinese medicinal preparation, it is granule, capsule, the tablet that is made according to certain weight proportion by following primary raw material, and raw material comprises Radix Salviae Miltiorrhizae, Rhizoma Coptidis, the Radix Astragali, Radix Puerariae, Rhizoma Chuanxiong, Radix Rhodiolae, Rhizoma Corydalis, Folium Ginkgo, Spina Gleditsiae, Flos Carthami, Rhizoma Cyperi, Radix Paeoniae Rubra totally ten two flavor Chinese crude drugs.Said preparation has the effect of blood circulation promoting and blood stasis dispelling, QI invigorating pain relieving, nourishing kidney yin, can be used for treating coronary heart disease, angina pectoris, and that disease is seen is uncomfortable in chest, chest pain, cardiopalmus, dizziness, insomnia, tinnitus, the acid of waist knee joint etc.Its medicine has bioavailability height, characteristics evident in efficacy.
The specific embodiment of form is described in further detail foregoing of the present invention by the following examples.Following example is based on the above-mentioned subject area of the present invention, but is not limited to following example.
The specific embodiment
Embodiment 1: granule
Adopt following prescription:
Radix Salviae Miltiorrhizae 65g Rhizoma Coptidis 80g Radix Astragali 65g
Radix Puerariae 110g Rhizoma Chuanxiong 65g Radix Rhodiolae 110g
Rhizoma Corydalis 80g Folium Ginkgo 45g Spina Gleditsiae 65g
Flos Carthami 80g Rhizoma Cyperi 45g Radix Paeoniae Rubra 80g
Can prepare as follows:
(1) get Rhizoma Chuanxiong 65g, Flos Carthami 80g, Rhizoma Cyperi 45g, mix, vapor distillation extracts volatile oil, and is standby;
(2) get Radix Salviae Miltiorrhizae 65g, Rhizoma Coptidis 80g, Rhizoma Corydalis 80g, extract 3 times with 10 times of amount 70% alcohol heating reflux, each 1.5 hours, collect and merge alcohol extract, filter, decompression filtrate recycling ethanol and concentrate ethanol extract extractum, standby;
(3) with Six-elements such as the Radix Astragali, Radix Puerariae, Radix Rhodiolaes, add 10 times of water gagings and decoct 4 times, each 1 hour, the gradation of decocting liquid filtered, filtrate decompression concentrate water extract extractum, standby;
(4) ethanol extract extractum and water extract extractum are merged mixing, drying is ground into fine powder, sieves, and adds the about 115g of starch, the about 68g of cane sugar powder, and mixing is used 80% alcohol granulation, and drying is put the spray of cold back and is added volatile oil, sieves, and makes granule.
Embodiment 2: capsule
Adopt following prescription:
Radix Salviae Miltiorrhizae 30g Rhizoma Coptidis 50g Radix Astragali 30g
Radix Puerariae 60g Rhizoma Chuanxiong 30g Radix Rhodiolae 60g
Rhizoma Corydalis 50g Folium Ginkgo 20g Spina Gleditsiae 30g
Flos Carthami 50g Rhizoma Cyperi 20g Radix Paeoniae Rubra 50g
Can prepare as follows:
(1) get Rhizoma Chuanxiong 30g, Flos Carthami 50g, Rhizoma Cyperi 20g, mix, vapor distillation extracts volatile oil, and is standby;
(2) get Radix Salviae Miltiorrhizae 30g, Rhizoma Coptidis 50g, Rhizoma Corydalis 50g, extract 2 times with 10 times of amount 70% alcohol heating reflux, each 1.5 hours, collect and merge alcohol extract, filter, decompression filtrate recycling ethanol and concentrate ethanol extract extractum, standby;
(3) with Six-elements such as the Radix Astragali, Radix Puerariae, Radix Rhodiolaes, add 10 times of water gagings and decoct 4 times, each 1 hour, the gradation of decocting liquid filtered, filtrate decompression concentrate water extract extractum, standby;
(4) ethanol extract extractum and water extract extractum are merged mixing, drying is ground into fine powder, sieves, and adding starch and lactose ratio are 5: 1 the about 80g of mixture, and mixing is granulated, and put the spray of cold back and add volatile oil, mixing, promptly encapsulated.
Embodiment 3: Film coated tablets
Adopt following prescription:
Radix Salviae Miltiorrhizae 90g Rhizoma Coptidis 100g Radix Astragali 90g
Radix Puerariae 120g Rhizoma Chuanxiong 90g Radix Rhodiolae 120g
Rhizoma Corydalis 100g Folium Ginkgo 60g Spina Gleditsiae 90g
Flos Carthami 100g Rhizoma Cyperi 60g Radix Paeoniae Rubra 100g
Can prepare as follows:
(1) get Rhizoma Chuanxiong 90g, Flos Carthami 100g, Rhizoma Cyperi 60g, mix, vapor distillation extracts volatile oil, and is standby;
(2) get Radix Salviae Miltiorrhizae 90g, Rhizoma Coptidis 100g, Rhizoma Corydalis 100g, extract 4 times with 10 times of amount 70% alcohol heating reflux, each 1.5 hours, collect and merge alcohol extract, filter, decompression filtrate recycling ethanol and concentrate ethanol extract extractum, standby;
(3) with Six-elements such as the Radix Astragali, Radix Puerariae, Radix Rhodiolaes, add 10 times of water gagings and decoct 4 times, each 1 hour, the gradation of decocting liquid filtered, filtrate decompression concentrate water extract extractum, standby;
(4) ethanol extract extractum and water extract extractum are merged, mixing, drying is ground into fine powder, sieves, the about 160g of adding starch, the about 50g of dextrin, mixing is used 90% alcohol granulation, and is air-dry, puts the spray of cold back and adds volatile oil, evenly mixed, suppresses in flakes, and the bag film-coat is promptly.
Claims (3)
1, a kind of treatment coronary heart disease, anginal compound Chinese medicinal preparation is characterized in that it comprises what unit of weight was made by the following raw material of part:
Radix Salviae Miltiorrhizae 30-90 part Rhizoma Coptidis 50-100 part Radix Astragali 30-90 part
Radix Puerariae 60-120 part Rhizoma Chuanxiong 30-90 part Radix Rhodiolae 60-120 part
Rhizoma Corydalis 50-100 part Folium Ginkgo 20-60 part Spina Gleditsiae 30-90 part
Flos Carthami 50-100 part Rhizoma Cyperi 20-60 part Radix Paeoniae Rubra 50-100 part
2, a kind of treatment coronary heart disease as claimed in claim 1, anginal compound Chinese medicinal preparation is characterized in that the weight proportion of each component is:
65 parts of 80 parts of Radixs Astragali of 65 portions of Rhizoma Coptidis of Radix Salviae Miltiorrhizae
110 parts of 65 parts of Radix Rhodiolaes of 110 parts of Rhizoma Chuanxiongs of Radix Puerariae
65 parts of 45 parts of Spina Gleditsiaes of 80 parts of Folium Ginkgos of Rhizoma Corydalis
80 parts of 45 parts of Radix Paeoniae Rubra of 80 portions of Rhizoma Cyperis of Flos Carthami
3, as the described a kind of treatment coronary heart disease of claim 1-2, anginal compound Chinese medicinal preparation, it is characterized in that the preparation method of this compound preparation is:
(1) get Rhizoma Chuanxiong, Flos Carthami, Rhizoma Cyperi, mix, vapor distillation extracts volatile oil, and is standby;
(2) get Radix Salviae Miltiorrhizae, Rhizoma Coptidis, Rhizoma Corydalis, extract 2～4 times with 10 times of amount 70% alcohol heating reflux, each 1.5 hours, collect and merge alcohol extract, filter, decompression filtrate recycling ethanol and concentrate ethanol extract extractum, standby;
(3) with Six-elements such as the Radix Astragali, Radix Puerariae, Radix Rhodiolaes, add 10 times of water gagings and decoct 4 times, each 1 hour, the gradation of decocting liquid filtered, filtrate decompression concentrate water extract extractum, standby;
(4) ethanol extract extractum and water extract extractum are merged mixing, drying is ground into fine powder, sieves, add starch or other preparations shaping adjuvants, mixing is granulated, put the spray of cold back and add volatile oil, make granule, capsule, tablet (plain sheet, Film coated tablets or coated tablet), promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200810115978 CN101618131A (en) | 2008-07-01 | 2008-07-01 | Chinese medicinal compound preparation for treating coronary heart disease and angina |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200810115978 CN101618131A (en) | 2008-07-01 | 2008-07-01 | Chinese medicinal compound preparation for treating coronary heart disease and angina |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101618131A true CN101618131A (en) | 2010-01-06 |
Family
ID=41511659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200810115978 Pending CN101618131A (en) | 2008-07-01 | 2008-07-01 | Chinese medicinal compound preparation for treating coronary heart disease and angina |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101618131A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102961529A (en) * | 2012-10-26 | 2013-03-13 | 郗光敏 | Traditional Chinese medicine composition for treating coronary heart disease |
| CN107261105A (en) * | 2017-06-26 | 2017-10-20 | 郑相国 | Treat the Chinese patent drug of cardiovascular and cerebrovascular disease |
| CN109331112A (en) * | 2018-12-14 | 2019-02-15 | 桂雪峰 | A kind of cardiopathic Chinese materia medica preparation of primary treatment qi stagnation and blood stasis type and its preparation process |
| CN109925399A (en) * | 2019-03-22 | 2019-06-25 | 江西九华药业有限公司 | A kind of compound traditional Chinese medicine composite and preparation method thereof for treating coronary disease and angina pectoris |
-
2008
- 2008-07-01 CN CN 200810115978 patent/CN101618131A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102961529A (en) * | 2012-10-26 | 2013-03-13 | 郗光敏 | Traditional Chinese medicine composition for treating coronary heart disease |
| CN102961529B (en) * | 2012-10-26 | 2014-08-13 | 郗光敏 | Traditional Chinese medicine composition for treating coronary heart disease |
| CN107261105A (en) * | 2017-06-26 | 2017-10-20 | 郑相国 | Treat the Chinese patent drug of cardiovascular and cerebrovascular disease |
| CN109331112A (en) * | 2018-12-14 | 2019-02-15 | 桂雪峰 | A kind of cardiopathic Chinese materia medica preparation of primary treatment qi stagnation and blood stasis type and its preparation process |
| CN109925399A (en) * | 2019-03-22 | 2019-06-25 | 江西九华药业有限公司 | A kind of compound traditional Chinese medicine composite and preparation method thereof for treating coronary disease and angina pectoris |
| CN109925399B (en) * | 2019-03-22 | 2021-12-14 | 江西九华药业有限公司 | Compound traditional Chinese medicine composition for treating coronary heart disease and angina pectoris and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100366280C (en) | Medicinal composition for treating hypertension, its preparation method and use | |
| CN100435831C (en) | Preparation for treating high blood pressure, high blood fat, obesity, and climacteric syndrome, and preparation method | |
| CN104587441A (en) | Cardiovascular disease regulating traditional Chinese medicine composition and preparation method thereof | |
| CN102847087A (en) | Preparation process of integration-type novel formulation of Cinnamomum cassia, Paeonia lactiflora and Anemarrhena asphodeloides decoction and production method thereof | |
| CN101618131A (en) | Chinese medicinal compound preparation for treating coronary heart disease and angina | |
| CN101172155A (en) | Novel dosage forms of pulse-activating gallbladder warming soup and method of preparing the same | |
| CN102579610B (en) | Chinese medicinal composition for treating cerebral hemorrhage and preparation method thereof | |
| CN1330345C (en) | Combination of Chinese traditional medicine for treating hyperlipemia, and preparation method | |
| CN1827136A (en) | Compound Chinese medicinal preparation for treating male sterility | |
| CN102488838A (en) | Traditional Chinese medicine composition used for treating viral myocarditis | |
| CN105250427A (en) | Pharmaceutical composition for treating heart diseases | |
| CN101912434B (en) | Medicament for treating hypertension and insomnia and preparation method thereof | |
| CN101461900B (en) | Pure medicinal formulation for treating arteriosclerosis | |
| CN1111054C (en) | Medicine for treating apoplexy and its preparing process | |
| CN102895621A (en) | Preparation technology and production method for integrated new formulation of turtle shell decocted pill | |
| CN104873685A (en) | Medicine for treating coronary heart disease | |
| CN100430072C (en) | Chinese-medicinal preparation for treating cardiovascular and cerebrovascular diseases | |
| CN101293067A (en) | Capsule for coronary disease | |
| CN1045892C (en) | Chinese medicine Guanxintong for preventing and curing coronary heart disease and angina pectoris, and producing process thereof | |
| CN101176743B (en) | Chinese medicine for curing coronary disease angina pectoris | |
| CN1244372C (en) | Chinese medicinal preparation for treating cardiac blood vessel disease and its preparation method | |
| CN101637565A (en) | Pure Chinese medicinal preparation for treating arrhythmia | |
| CN1168473C (en) | Chinese medicine prepn for treating arterioscleriosis | |
| CN1363386A (en) | Composition Chinese-medicinal herb pieces and preparing process thereof | |
| CN105832934A (en) | Traditional Chinese medicine for treating hypertension |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20100106 |