CN106983849A - A kind of Chinese medicine for treating apoplexy and application - Google Patents

A kind of Chinese medicine for treating apoplexy and application Download PDF

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Publication number
CN106983849A
CN106983849A CN201710360148.XA CN201710360148A CN106983849A CN 106983849 A CN106983849 A CN 106983849A CN 201710360148 A CN201710360148 A CN 201710360148A CN 106983849 A CN106983849 A CN 106983849A
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China
Prior art keywords
medicine
apoplexy
radix
angelicae sinensis
almond
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CN201710360148.XA
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Chinese (zh)
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不公告发明人
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Suzhou Jiao In Nano Science And Technology Co Ltd
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Suzhou Jiao In Nano Science And Technology Co Ltd
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Priority to CN201710360148.XA priority Critical patent/CN106983849A/en
Publication of CN106983849A publication Critical patent/CN106983849A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of Chinese medicine for treating apoplexy and its application, described medicine with following raw materials by being made:Rhizoma zingiberis, Ligusticum wallichii, Radix Angelicae Sinensis, radix glycyrrhizae, radix scutellariae, osmanthus heart, almond, gypsum, jute.The present invention specify that the formula and preparation method of medicine, overcome the deficiency of existing treatment apoplexy medicine, and function admirable, the therapeutic effect of Patients with Apoplexy After is good.

Description

A kind of Chinese medicine for treating apoplexy and application
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine for treating apoplexy and application.
Background technology
Apoplexy usually brings three inclined symptoms:Hemiplegia, hemidysesthesia, hemianopsia, and lost with dysphonia or motility Language.In a big way or multiple relapse sequelae symptom can leave spirit and dysnoesia.Therefore to the prevention of apoplexy with controlling The research for the treatment of causes the very big concern of people always.
Chinese invention patent 105658667A, which is related to, treats apoplexy such as ishemic stroke such as acute ischemic stroke Method, and it is for example acute scarce with apoplexy such as ishemic stroke to be directed to use with such as natalizumab reduction of VLA-4 antagonists The method of the related infraction size of courageous and upright apoplexy and/or other neurologically handicappeds.It was found that, such as when specified after apoplectic seizure Between when being administered in section, VLA-4 antagonists such as natalizumab can effectively reduce apoplexy such as ishemic stroke for example The infraction size of the acute ischemic stroke neurologically handicapped related to other.
Chinese invention patent 101843851B is related to the preparation of anti-hypertension apoplexy medicine, it is desirable to provide a kind of anti-hypertension Dendrobium officinale nimodipine combination medicine of apoplexy and preparation method thereof.The dendrobium candidum Nimodipine of the anti-hypertension apoplexy is closed With medicine, effective component includes the mass ratio of dendrobium officinale aqueous extract and Nimodipine, dendrobium officinale aqueous extract and Nimodipine For 1.0~4.0: 0.12~0.24.The invention is additionally provided in the medicinal extract based on the medicine, granule, tablet, capsule, medicine Mesosome and preparation method thereof.The invention, which discloses the use of combination with medication and dendrobium candidum or the independent of Nimodipine any one, to be made With comparing, not only can be faster reduce blood pressure is better able to the reduction death rate, extension life span.Such as spy The medicine for determining purposes is used, and can relax lasting reduction hyperpietic's blood pressure, delays hypertensive cerebral vascular infringement progress, To mankind's preventing hypertension apoplexy, the disabling of reduction high blood pressure, fatal rate are significant.
Chinese invention patent 102614234B discloses a kind of Aggrenox compositions and tablet and preparation method thereof.Side Method:Crude drug Ligusticum wallichii and Radix Angelicae Sinensis are added into 10 times of 70% ethanol of amount for the first time, extractor is placed in, keeps 70-100 DEG C of extraction 2 small When, extract solution is filtered out, the first extract solution is obtained, solid filter residue is stand-by.8 times of 70% ethanol of amount are added in solid filter residue, are placed in Extractor, is kept for 70-100 DEG C extract 1.5 hours, filters out extract solution, filter out extract solution, obtains the second extract solution and solid filter Slag.Mixed extract, under the conditions of temperature is 60-70 DEG C, no alcohol taste is concentrated under reduced pressure into mixed liquor, obtains extracting concentration Thing, the relative density of concentrate is 1.10~1.30, and its Midst density is measured at 60 DEG C;Add what is crushed in extraction concentrat Natural borneol dissolves, and produces Pharmaceutical composition;The weight proportion of medicinal material used is:10~50 parts of Ligusticum wallichii, Radix Angelicae Sinensis 50~10 part, day Right 1~10 part of borneol.Obtained composition has obvious repair to apoplexy, the impaired of cranial nerve function.
However, the effect of the medicine of Current therapeutic apoplexy is not good, apoplexy is still to seriously endanger human health and life The common refractory disease of safety.According to statistics, the annual patient for occurring headstroke of China is just up to 2,000,000.Now survive apoplexy Patient 7,000,000, wherein the different degrees of disability of 4,500,000 patients and can't take care of oneself, disability rate is up to 75%.It is Chinese every Year stroke patient dead 1,200,000.
The content of the invention
Goal of the invention:In order to improve the therapeutic effect of stroke patient, the invention provides a kind of Chinese medicine for treating apoplexy.
To achieve the above object, by a large amount of practices of inventor, medicine of the invention is made up of following raw materials:
Rhizoma zingiberis, Ligusticum wallichii, Radix Angelicae Sinensis, radix glycyrrhizae, radix scutellariae, osmanthus heart, almond, gypsum, jute.
Preferably, to being limited below the work by weight ratio of each component:
1 part of rhizoma zingiberis;Ligusticum wallichii, each 0.8 ~ 1.5 part of Radix Angelicae Sinensis, radix glycyrrhizae, radix scutellariae;Each 8 ~ 12 parts of osmanthus heart, almond;Gypsum, jute each 15 ~ 25 Part.
Further preferably, medicine of the invention is made up by weight of following raw materials according:
Rhizoma zingiberis, Ligusticum wallichii, each 1 part of Radix Angelicae Sinensis, radix glycyrrhizae, radix scutellariae;Each 10 parts of osmanthus heart, almond;Each 20 parts of gypsum, jute.
The formulation of pharmaceutical composition of the present invention can be the medical science such as decoction, pill, powder, tablet, capsule, granule Upper acceptable formulation, preparation is processed by existing common process.
Present invention additionally comprises said medicine for treating the application in apoplexy.
The pharmaceutical formulation of the present invention, for the pathogenesis of apoplexy, has warming spleen and stomach for dispelling cold, Back to Yang Tongmai, temperature from rhizoma zingiberis The effect of lungization drink;Ligusticum wallichii has promoting qi circulation and relieving pain, warming kidney and enhancing yang, the broken product effect of stagnation resolvation;Radix Angelicae Sinensis has the effect of replenishing and activating blood;It is sweet Grass, which has, invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, lassitude hypodynamia, the heart Throb with fear shortness of breath, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus alleviate drug toxicity, strong effect;Almond has drop The effect of blood fat;Radix scutellariae has the effect of heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, hypotensive;Zhu Fang is shared, and can reach sample The simultaneous purpose controlled, has good curative effect to symptoms such as apoplexy, cerebral infarction, miocardial infarction, acute cerebral hemorrhage diseases.
Embodiment
The present invention is further illustrated with reference to embodiment.
Take rhizoma zingiberis, Ligusticum wallichii, each 10 grams of Radix Angelicae Sinensis, radix glycyrrhizae, radix scutellariae;Each 100 grams of osmanthus heart, almond;Each 200 grams of gypsum, jute, it is standby With;Jute is put into 10 liters of water, boiled, is filtered, is added other all medicinal materials, boil, obtain decoction.

Claims (5)

1. a kind of medicine, it is characterised in that the medicine is by rhizoma zingiberis, Ligusticum wallichii, Radix Angelicae Sinensis, radix glycyrrhizae, radix scutellariae, osmanthus heart, almond, gypsum, Huang Fiber crops composition.
2. a kind of medicine according to claim 1, it is characterised in that each component of described medicine example in mass ratio is matched It is as follows:1 part of rhizoma zingiberis;Ligusticum wallichii, each 0.8 ~ 1.5 part of Radix Angelicae Sinensis, radix glycyrrhizae, radix scutellariae;Each 8 ~ 12 parts of osmanthus heart, almond;Gypsum, jute each 15 ~ 25 parts.
3. a kind of medicine according to claim 2, it is characterised in that each component of described medicine example in mass ratio is matched It is as follows:Rhizoma zingiberis, Ligusticum wallichii, each 1 part of Radix Angelicae Sinensis, radix glycyrrhizae, radix scutellariae;Each 10 parts of osmanthus heart, almond;Each 20 parts of gypsum, jute.
4. a kind of medicine according to claim 1, it is characterised in that the formulation of described medicine can be decoction, pill, The medically acceptable formulation such as powder, tablet, capsule, granule.
5. a kind of medicine according to claim 1-4, it is characterised in that described medicinal application is in treatment apoplexy.
CN201710360148.XA 2017-05-20 2017-05-20 A kind of Chinese medicine for treating apoplexy and application Withdrawn CN106983849A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108187018A (en) * 2018-03-15 2018-06-22 天津白大夫健康管理有限公司 One kind prolongs raw granular recipe

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11349487A (en) * 1998-06-03 1999-12-21 Kwang Dong Pharmaceut Co Ltd Woowhangchungshimwon composition of new recipe and its production
CN102895632A (en) * 2011-07-29 2013-01-30 苏州知微堂生物科技有限公司 Preparation technology and production method for integrated new formulation of life-prolonging decotion

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11349487A (en) * 1998-06-03 1999-12-21 Kwang Dong Pharmaceut Co Ltd Woowhangchungshimwon composition of new recipe and its production
CN102895632A (en) * 2011-07-29 2013-01-30 苏州知微堂生物科技有限公司 Preparation technology and production method for integrated new formulation of life-prolonging decotion

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
吴积海: "脑中风从肺论治", 《河南中医学院学报》 *
张永全: "《古今录验》续命汤新用", 《新中医》 *
陈川等: "《中医名方临床集验》", 31 January 2017, 上海科学技术出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108187018A (en) * 2018-03-15 2018-06-22 天津白大夫健康管理有限公司 One kind prolongs raw granular recipe

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Application publication date: 20170728