CN105148212A - Traditional Chinese medicine composition for treating diabetes and hypertension combined disease - Google Patents
Traditional Chinese medicine composition for treating diabetes and hypertension combined disease Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine composition for treating a diabetes and hypertension combined disease. The traditional Chinese medicine composition is prepared from, by weight, 15 parts to 25 parts of radix rehmanniae preparata, 5 parts to 15 parts of cornus officinalis, 5 parts to 15 parts of Chinese yams, 5 parts to 15 parts of rhizoma alismatis, 5 parts to 15 parts of poria cocos, 3 parts to 13 parts of root bark of peony trees, 3 parts to 13 parts of uncaria rhynchophylla, 3 parts to 13 parts of wolfberries, 3 parts to 13 parts of curcuma aromatica and 3 parts to 13 parts of rhizoma anemarrhenae. The radix rehmanniae preparata has the effects of tonifying kidney yin and strengthening and nourishing marrow and essence, and serves as a monarch drug; the cornus officinalis is sour in taste, warm in nature and capable of nourishing the kidney and the liver; the Chinese yams have the effects of nourishing the kidney and tonifying the spleen; the medicinal materials jointly act, the liver and the kidney can be nourished, and three yins are jointly reinforced to be gathered. According to the traditional Chinese medicine composition, the raw materials are abundant, the components are scientific, and medicine compatibility is reasonable; the traditional Chinese medicine composition has the advantages of being high in effect taking speed, short in treatment course, small in side effect and the like, and is particularly suitable for treating the diabetes and the hypertension combined disease.
Description
Technical field
The present invention relates to technical field of pharmaceuticals, be specifically related to a kind of Chinese medicine composition for the treatment of Diabetes with Hypertension.
Background technology
Diabetes are one group take hyperglycemia as the metabolic disease of feature caused by defect of insulin secretion and/or insulin action obstacle.Persistent high blood sugar and long-term metabolic are disorderly etc. can cause body tissue's organ, particularly eye, kidney, cardiovascular and neural infringement and dysfunction thereof and exhaustion.Severe patient can cause dehydration, the acute complications such as electrolyte disturbance and acid base imbalance ketoacidosis and Hyperosmotic coma.
And many diabeticss clinically, often with hypertension, and hyperpietic is also more with diabetes, and both are called as homology disease.Diabetes, hypertension two kinds of diseases are in the cause of disease, interact or hazardness all exists intercommunity, therefore usually merge outbreak, form Diabetes with Hypertension.In diabetics, hypertension prevalence is significantly higher than hypertension prevalence in population, and about 50% ~ 70%.The clinical symptoms of patient has headache, vertigo and tinnitus, soreness of the waist and knees, susceptible to lose temper due to restlessness, restless sleep, dreaminess, or double hypochondriac pain, often because to bother or angry and dizzy, headache increases the weight of, flushing, bitter taste, red tongue, few tongue or yellow and thin fur, stringy and thready pulse when dryness and uneasy feeling of the eye, blurring of vision, the few Tianjin of dry mouth and throat, dysphoria with feverish sensation in the chest palms and soles, weak, face.Easily there is the diseases such as coronary heart disease, cerebrovascular, arteriosclerosis in patient.Long-term clinical practice proves with research, and Chinese medicine demonstrates unique advantage in control diabetic nephropathy.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide that a kind of medical material component science, compatibility are supported rationally, mutually, side effect is little, evident in efficacy, the Chinese medicine composition for the treatment of Diabetes with Hypertension.
In order to achieve the above object, the technical scheme that the present invention takes is:
A kind of Chinese medicine composition for the treatment of Diabetes with Hypertension, its component is by weight: 15 ~ 25 parts, Radix Rehmanniae Preparata, Fructus Corni 5 ~ 15 parts, Rhizoma Dioscoreae 5 ~ 15 parts, Rhizoma Alismatis 5 ~ 15 parts, 5 ~ 15 parts, Poria, Cortex Moutan 3 ~ 13 parts, Ramulus Uncariae Cum Uncis 3 ~ 13 parts, Fructus Lycii 3 ~ 13 parts, Radix Curcumae 3 ~ 13 parts, the Rhizoma Anemarrhenae 3 ~ 13 parts.
As preferred component, its component is by weight: 17 ~ 23 parts, Radix Rehmanniae Preparata, Fructus Corni 7 ~ 13 parts, Rhizoma Dioscoreae 7 ~ 13 parts, Rhizoma Alismatis 7 ~ 13 parts, 7 ~ 13 parts, Poria, Cortex Moutan 5 ~ 11 parts, Ramulus Uncariae Cum Uncis 5 ~ 11 parts, Fructus Lycii 5 ~ 11 parts, Radix Curcumae 5 ~ 11 parts, the Rhizoma Anemarrhenae 5 ~ 11 parts.
As preferred component, its component is by weight: 19 ~ 21 parts, Radix Rehmanniae Preparata, Fructus Corni 9 ~ 11 parts, Rhizoma Dioscoreae 9 ~ 11 parts, Rhizoma Alismatis 9 ~ 11 parts, 9 ~ 11 parts, Poria, Cortex Moutan 7 ~ 9 parts, Ramulus Uncariae Cum Uncis 7 ~ 9 parts, Fructus Lycii 7 ~ 9 parts, Radix Curcumae 7 ~ 9 parts, the Rhizoma Anemarrhenae 7 ~ 9 parts.
As better composition, its component is by weight: 20 parts, Radix Rehmanniae Preparata, Fructus Corni 10 parts, Rhizoma Dioscoreae 10 parts, Rhizoma Alismatis 10 parts, 10 parts, Poria, Cortex Moutan 8 parts, Ramulus Uncariae Cum Uncis 8 parts, Fructus Lycii 8 parts, Radix Curcumae 8 parts, the Rhizoma Anemarrhenae 8 parts.
Instructions of taking: be decocted in water for oral dose, 1 day 1 dose, point sooner or later 2 decoction being taken warmly.Within 1 month, be 1 course for the treatment of, after 1 course for the treatment of, the 2nd course for the treatment of is continued in 3 ~ 5 days in interval.
Medicine of the present invention has following pharmacology:
Radix Rehmanniae Preparata, the property of medicine, there is effect that moist, beneficial essence of enriching blood fills out marrow, be mainly used in sallow, the dizzy cardiopalmus of blood tiger, menoxenia, collapse that more than, hepatic and renal YIN deficiency, hectic fever night sweat, seminal emission sexual impotence, infertility, soreness of the waist and knees, Hiccough and deaf, the head are dim-sighted, early whitening of beard and hair, quench one's thirst, constipation, the symptoms such as dyspnea with rapid and short breath of suffering from a deficiency of the kidney.
Fructus Corni, property of medicine sour in the mouth, slightly warm in nature, have liver and kidney tonifying, the solid de-effect of convergence, is mainly used in the symptoms such as waist is had a dizzy spell, deafness and tinnitus, soreness of the waist and knees, Xian essence spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding.
Rhizoma Dioscoreae, the property of medicine is sweet, flat, has spleen reinforcing, supports lung, reinforces the kidney, effect of benefit essence, is mainly used in diarrhea due to hypofunction of the spleen, lack of appetite edema, cough and asthma due to lung deficiency, quenches one's thirst, passes out semen, leukorrhagia, frequent micturition of suffering from a deficiency of the kidney, external control the symptom such as carbuncle, scrofula.
Rhizoma Alismatis, property of medicine sweet in the mouth, light, cold in nature, there is promoting diuresis to eliminate damp pathogen, expel the heat-evil treating stranguria effect, be mainly used in dysuria, the puckery pain of pyretic stranguria, edema distension, have loose bowels, dizziness due to fluid-retention, the symptom such as seminal emission.
Poria, property of medicine bitter in the mouth, pungent, property are micro-wet, have effect of expelling wind and dampness, dispersing cold for relieving pain, are mainly used in the symptoms such as anemofrigid-damp arthralgia, lumbocrural pain, headache toothache.
Cortex Moutan, the property of medicine is arduous, cool, be slightly cold, there is effect of heat clearing away, promoting blood circulation to remove blood stasis, be mainly used in the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, pathogenic bacteria later stage brimful of tears hot Fu Yin divides heating, deficiency of YIN osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhea, carbuncle sore tumefacting virus, fall and flutter the symptom such as the pain of injury, beriberoid pyretic arthralgia.
Ramulus Uncariae Cum Uncis, property of medicine sweetness and bitterness, is slightly cold, and has effect of heat clearing away suppressing the hyperactive liver, relieving spasm by subduing liver-wind, is mainly used in the symptoms such as infantile convulsion, night cry, intenseness of heat wind symptom, eclamposia, dizziness due to hyperactivity of liver-YANG, liver-fire distending pain in the head.
Fructus Lycii, property of medicine sweet in the mouth, property are flat, have effect of nourishing the liver, nourishing kidney, lung moistening, are mainly used in caused by liver and kidney deficiency, have a dizzy spell, visual one clear, the expensive essence of soreness of the waist and knees, sexual impotence, cough due to consumptive disease, the symptoms such as taking fluids profusely of quenching one's thirst.
Radix Curcumae, property of medicine acrid in the mouth, hardship, cold, there is effect of invigorate blood circulation only energy, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, depressed liver-energy dispersing and function of gallbladder promoting, be mainly used in breast abdomen and coerce the symptoms such as all pains of rib, dysmenorrhes, amenorrhea, mass in the abdomen caking, calentura coma, demented, infantile convulsion, haematemesis, nosebleed are standby, stranguria with blood, sand Stranguria, jaundice.
The Rhizoma Anemarrhenae, property of medicine bitter in the mouth, cold in nature, there is effect of clearing away heat-fire, nourshing Yin and drynsessmoistening prescription, relieving restlessness of quenching the thirst, be mainly used in epidemic febrile disease, high hot excessive thirst, cough and asthma, cough caused by dryness, constipation, osteopyrexia and fever, restlessness of asrhenia type and insomnia, the symptoms such as stranguria with turbid discharge of quenching one's thirst.
Compared with prior art, the benefit that the present invention has: Radix Rehmanniae Preparata nourishing kidney-yin, strengthening and nourishing marrow and essence are as monarch drug, and Fructus Corni sour in the mouth is warm in nature, can grow, kidney the liver benefiting, Rhizoma Dioscoreae nourishing kidney spleen reinforcing, and all medicines share, can nourishing the liver and kidney, becomes three cloudy and mend to receive benefit altogether.And abundant raw materials of the present invention, component science, compatibility is reasonable, has the advantages such as rapid-action, short treating period, side effect be little.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
Patient data: patient 58 example, wherein man 35 example, female 23 example, at 41 ~ 69 years old age, the course of disease is the shortest 3 years, the longest 10 years.
Efficacy determination: according to the therapeutic effect criterion about hypertension in " new Chinese medicine guideline of clinical investigations ", effective: 1. diastolic pressure reduction >=1.3Pa, and enter normal range; 2. diastolic pressure does not enter normal range, but reduction >=2.7kPa.Any one wherein must be possessed.Effective: the numerical value <1.3a of 1. diastolic pressure reduction, but enter normal range; 2. diastolic pressure reduces 1.3 ~ 1.5kPa compared with before treatment, but does not enter normal range; 3. systolic pressure reduction >=4kPa compared with before treatment.Any one wherein must be possessed.Invalid: after treatment, not reach above standard person.
Treatment total effective rate=(recovery from illness+effective+effectively)/total number of cases × 100%.
Treatment statistical result is as follows:
Effective, 38 examples, account for 65.52%; Effectively, 16 examples, account for 27.59%, invalid, 4 examples; Account for 6.9%; Total effective rate is 93.1%.
Visible, Chinese medicine composition of the present invention can safe and effective treatment Diabetes with Hypertension disease.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described.
Embodiment 1
First, take each component in proportion: 25 parts, Radix Rehmanniae Preparata, Fructus Corni 15 parts, Rhizoma Dioscoreae 15 parts, Rhizoma Alismatis 15 parts, 15 parts, Poria, Cortex Moutan 3 parts, Ramulus Uncariae Cum Uncis 3 parts, Fructus Lycii 3 parts, Radix Curcumae 3 parts, the Rhizoma Anemarrhenae 3 parts.
Instructions of taking: be decocted in water for oral dose, 1 day 1 dose, point sooner or later 2 decoction being taken warmly.Within 1 month, be 1 course for the treatment of, after 1 course for the treatment of, the 2nd course for the treatment of is continued in 3 days in interval.
Embodiment 2
First, take each component in proportion: 23 parts, Radix Rehmanniae Preparata, Fructus Corni 13 parts, Rhizoma Dioscoreae 13 parts, Rhizoma Alismatis 13 parts, 13 parts, Poria, Cortex Moutan 5 parts, Ramulus Uncariae Cum Uncis 5 parts, Fructus Lycii 5 parts, Radix Curcumae 5 parts, the Rhizoma Anemarrhenae 5 parts.
Instructions of taking: be decocted in water for oral dose, 1 day 1 dose, point sooner or later 2 decoction being taken warmly.Within 1 month, be 1 course for the treatment of, after 1 course for the treatment of, the 2nd course for the treatment of is continued in 4 days in interval.
Embodiment 3
First, take each component in proportion: 20 parts, Radix Rehmanniae Preparata, Fructus Corni 10 parts, Rhizoma Dioscoreae 10 parts, Rhizoma Alismatis 10 parts, 10 parts, Poria, Cortex Moutan 8 parts, Ramulus Uncariae Cum Uncis 8 parts, Fructus Lycii 8 parts, Radix Curcumae 8 parts, the Rhizoma Anemarrhenae 8 parts.
Instructions of taking: be decocted in water for oral dose, 1 day 1 dose, point sooner or later 2 decoction being taken warmly.Within 1 month, be 1 course for the treatment of, after 1 course for the treatment of, the 2nd course for the treatment of is continued in 5 days in interval.
Embodiment 4
First, take each component in proportion: 18 parts, Radix Rehmanniae Preparata, Fructus Corni 8 parts, Rhizoma Dioscoreae 8 parts, Rhizoma Alismatis 8 parts, 8 parts, Poria, Cortex Moutan 10 parts, Ramulus Uncariae Cum Uncis 10 parts, Fructus Lycii 10 parts, Radix Curcumae 10 parts, the Rhizoma Anemarrhenae 10 parts.
Instructions of taking: be decocted in water for oral dose, 1 day 1 dose, point sooner or later 2 decoction being taken warmly.Within 1 month, be 1 course for the treatment of, after 1 course for the treatment of, the 2nd course for the treatment of is continued in 3 days in interval.
Embodiment 5
First, take each component in proportion: 15 parts, Radix Rehmanniae Preparata, Fructus Corni 5 parts, Rhizoma Dioscoreae 5 parts, Rhizoma Alismatis 5 parts, 5 parts, Poria, Cortex Moutan 13 parts, Ramulus Uncariae Cum Uncis 13 parts, Fructus Lycii 13 parts, Radix Curcumae 13 parts, the Rhizoma Anemarrhenae 13 parts.
Instructions of taking: be decocted in water for oral dose, 1 day 1 dose, point sooner or later 2 decoction being taken warmly.Within 1 month, be 1 course for the treatment of, after 1 course for the treatment of, the 2nd course for the treatment of is continued in 3 days in interval.
It should be pointed out that above case is only the representational example of the present invention.Obviously, technical scheme of the present invention is not limited to above-described embodiment, can also have many degeneration.
Claims (4)
1. treat the Chinese medicine composition of Diabetes with Hypertension for one kind, it is characterized in that, its component is by weight: 15 ~ 25 parts, Radix Rehmanniae Preparata, Fructus Corni 5 ~ 15 parts, Rhizoma Dioscoreae 5 ~ 15 parts, Rhizoma Alismatis 5 ~ 15 parts, 5 ~ 15 parts, Poria, Cortex Moutan 3 ~ 13 parts, Ramulus Uncariae Cum Uncis 3 ~ 13 parts, Fructus Lycii 3 ~ 13 parts, Radix Curcumae 3 ~ 13 parts, the Rhizoma Anemarrhenae 3 ~ 13 parts.
2. a kind of Chinese medicine composition for the treatment of Diabetes with Hypertension according to claim 1, it is characterized in that, its component is by weight: 17 ~ 23 parts, Radix Rehmanniae Preparata, Fructus Corni 7 ~ 13 parts, Rhizoma Dioscoreae 7 ~ 13 parts, Rhizoma Alismatis 7 ~ 13 parts, 7 ~ 13 parts, Poria, Cortex Moutan 5 ~ 11 parts, Ramulus Uncariae Cum Uncis 5 ~ 11 parts, Fructus Lycii 5 ~ 11 parts, Radix Curcumae 5 ~ 11 parts, the Rhizoma Anemarrhenae 5 ~ 11 parts.
3. a kind of Chinese medicine composition for the treatment of Diabetes with Hypertension according to claim 2, it is characterized in that, its component is by weight: 19 ~ 21 parts, Radix Rehmanniae Preparata, Fructus Corni 9 ~ 11 parts, Rhizoma Dioscoreae 9 ~ 11 parts, Rhizoma Alismatis 9 ~ 11 parts, 9 ~ 11 parts, Poria, Cortex Moutan 7 ~ 9 parts, Ramulus Uncariae Cum Uncis 7 ~ 9 parts, Fructus Lycii 7 ~ 9 parts, Radix Curcumae 7 ~ 9 parts, the Rhizoma Anemarrhenae 7 ~ 9 parts.
4. a kind of Chinese medicine composition for the treatment of Diabetes with Hypertension according to claim 3, it is characterized in that, its component is by weight: 20 parts, Radix Rehmanniae Preparata, Fructus Corni 10 parts, Rhizoma Dioscoreae 10 parts, Rhizoma Alismatis 10 parts, 10 parts, Poria, Cortex Moutan 8 parts, Ramulus Uncariae Cum Uncis 8 parts, Fructus Lycii 8 parts, Radix Curcumae 8 parts, the Rhizoma Anemarrhenae 8 parts.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108403902A (en) * | 2018-05-02 | 2018-08-17 | 李鹏康 | A kind of Chinese medicine composition for treating hypertension and its complication |
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| CN1159337A (en) * | 1996-10-08 | 1997-09-17 | 马利 | Pill for treating diabetes |
| CN1362220A (en) * | 2001-01-08 | 2002-08-07 | 杨孟君 | Nano Anemarrhenae, phellodendri and Rehmanniae medicine and its preparation |
| CN102430029A (en) * | 2011-11-25 | 2012-05-02 | 河南工业大学 | Nano microcapsule for six ingredients with rehmannia and preparation process thereof |
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2015
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Patent Citations (3)
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| CN1159337A (en) * | 1996-10-08 | 1997-09-17 | 马利 | Pill for treating diabetes |
| CN1362220A (en) * | 2001-01-08 | 2002-08-07 | 杨孟君 | Nano Anemarrhenae, phellodendri and Rehmanniae medicine and its preparation |
| CN102430029A (en) * | 2011-11-25 | 2012-05-02 | 河南工业大学 | Nano microcapsule for six ingredients with rehmannia and preparation process thereof |
Non-Patent Citations (2)
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| 耿以安，等: "六味地黄汤加味治疗糖尿病合并高血压", 《中国实用医药》 * |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108403902A (en) * | 2018-05-02 | 2018-08-17 | 李鹏康 | A kind of Chinese medicine composition for treating hypertension and its complication |
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Application publication date: 20151216 |