CN107137524A - A kind of compound essential oil refreshed the mind and preparation method thereof - Google Patents
A kind of compound essential oil refreshed the mind and preparation method thereof Download PDFInfo
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
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- C11B9/02—Recovery or refining of essential oils from raw materials
- C11B9/022—Refining
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- A61K2236/30—Extraction of the material
- A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
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Abstract
The present invention relates to a kind of compound essential oil refreshed the mind and preparation method thereof.Described compound essential oil includes the preparing raw material of following parts by weight：10~20 parts of 0.1~0.8 part of P-Cymene, 25~35 parts of rosemary oil, 20~30 parts of Lysimachia foenum-graecum, 20~30 parts of Pon orange peel, 15~25 parts of the fruit of a cubeb litsea tree, 1~3 part of bergamio, 1~3 part of oak moss absolute, 2~8 parts of perilla alcohol, 10~16 parts of menthol, 0.1~0.5 part of Rome chamomile essential oil, 0.05~0.2 part of Ceylon cinnamon peel essential oil and camellia seed oil.Compound essential oil that the present invention is provided work it is rapid, it is evident in efficacy, can effectively keeping tensions down mood, mood of releiving, refresh the mind, fatigue-relieving, and property is stable, safe and non-stimulating property, is adapted to long-term use, and preparation technology is simple, cost is relatively low.
Description
Technical field
The invention belongs to plants essential oil technical field, and in particular to a kind of compound essential oil refreshed the mind and its preparation side
Method.
Background technology
With people's learning life and the quickening of work rhythm, life stress is continued to increase, and increasing people is easy
There are the various fatigue symptoms such as lassitude and weak, lassitude, drowsy, alliteration be forgetful, not only influence working and learning efficiency,
And impair one's health, or even easily cause accident.In order to be able to keep a cool head at work, many people are liked by drinking
The mode of coffee or strong tea is refreshed oneself, but caffeine is heavy dose of or be used for a long time and human body can be caused damage, and also results in
Addiction, once disable down in spirits occurs, it is tired tired from head to foot, can also aggravate hypertension, induced osteoporosis etc..And drink for a long time
Strong tea easily causes anaemia, various nutrients to be lost in, and aggravates cardiac load.
It is many currently for the countermeasure refreshed the mind.More than Western medicine using antianxiety, refresh oneself and the medicine such as trophic nerve
Treatment, though obtaining certain curative effect, medication is single and long-term taking knows from experience the larger toxic side effect of generation to people.Chinese traditional treatment
Conditioning is more based on various tonics, but exist course for the treatment of length, slowly effect, curative effect it is not notable, it is unstable the shortcomings of.External essence oil has
It is effective in cure notable, the advantages of easy to use and carry, by stimulating brain nervous cell, make brain cell active, reach
Dispelling fatigue, the effect refreshed the mind, with good DEVELOPMENT PROSPECT.Such as Publication No. CN 101732458B Chinese patent
A kind of compound essential oil for refreshing the mind antifatigue and the hygenic towelette containing the essential oil are disclosed, the compound essential oil is by following parts by weight
The raw material of proportioning is prepared from：20~50 parts of menthol, 0.5~2 part of Yilan caul-fat, 15~25 parts of lavender oil, rosemary leave
Oil 3~10 parts, 20~30 parts of orange oil, 15~25 parts of cineole, 20~40 parts of petit grain lemon oil, 0.1~0.2 part of peppermint oil,
20~50 parts of caryophyllus oil, 30~55 parts of spearmint oil, the compound essential oil have refresh the mind, the function of dispelling fatigue, but cost
It is higher.
It is therefore desirable to develop a kind of effective, stable and lower-cost product easy to use, safe to meet market
Demand.
The content of the invention
To solve technical problem present in prior art, present invention aims at providing, a kind of easy to use, effect is true
Cut and have no toxic side effect, the lower-cost compound essential oil refreshed the mind and preparation method thereof.
A kind of compound essential oil refreshed the mind that the present invention is provided, includes the preparing raw material of following parts by weight：P-Cymene
0.1~0.8 part, 25~35 parts of rosemary oil, 20~30 parts of Lysimachia foenum-graecum, 20~30 parts of Pon orange peel, 15~25 parts of the fruit of a cubeb litsea tree, acetic acid
10~20 parts of fragrant 1~3 part of camphor tree ester, 1~3 part of oak moss absolute, 2~8 parts of perilla alcohol, 10~16 parts of menthol and camellia seed oil.
Preferably, described compound essential oil includes the preparing raw material of following parts by weight：0.5 part of P-Cymene, rosemary oil
30 parts, it is 25 parts of Lysimachia foenum-graecum, 25 parts of Pon orange peel, 20 parts of the fruit of a cubeb litsea tree, 2 parts of bergamio, 2 parts of oak moss absolute, 5 parts of perilla alcohol, thin
15 parts of 12 parts of lotus alcohol and camellia seed oil.
Further, described compound essential oil also includes the preparing raw material of following parts by weight：Rome chamomile essential oil 0.1~
0.5 part, 0.05~0.2 part of Ceylon cinnamon peel essential oil.
Preferably, described compound essential oil includes the preparing raw material of following parts by weight：0.5 part of P-Cymene, rosemary oil
30 parts, it is 25 parts of Lysimachia foenum-graecum, 25 parts of Pon orange peel, 20 parts of the fruit of a cubeb litsea tree, 2 parts of bergamio, 2 parts of oak moss absolute, 5 parts of perilla alcohol, thin
15 parts of 12 parts of lotus alcohol, 0.4 part of Rome chamomile essential oil, 0.1 part of Ceylon cinnamon peel essential oil and camellia seed oil.
Further, the preparation method of the P-Cymene comprises the following steps：
(1) by folium artemisiae argyi crush fill in supercritical carbon dioxide extraction kettle, set extraction kettle parameter as：Upper pressure
25MPa, push 48 DEG C of 27MPa, temperature；Set extraction-container parameter as：Pressure 5MPa, temperature 60 C, are passed through CO 2 fluid
Extraction, collects medicinal extract in extraction-container, stops when yield is up to 2.5%, produce folium artemisiae argyi medicinal extract；
(2) molecular distillation is carried out to folium artemisiae argyi medicinal extract made from step (1), is specially：
1. start setup parameter is 70 DEG C of jacket temperature, charging rate 130ML/H, evaporation layer temperature 70 C, condensate layer temperature
Spend 40 DEG C, below pressure 0.1Pa；
2. liquid nitrogen is poured into cold well；
3. the 70 DEG C of water-baths of folium artemisiae argyi medicinal extract are in a liquid state, pour feed well into, start charging after equipment reaches setup parameter；
4. light component bottle is collected into P-Cymene, and restructuring sub-bottle is collected into wax, and heel bottle is collected into steaming excess, produces Chinese mugwort
Leaf essential oil.
In addition, the present invention also provides a kind of preparation method of the described compound essential oil refreshed the mind, it includes following step
Suddenly：
(1) Lysimachia foenum-graecum, Pon orange peel, the fruit of a cubeb litsea tree are taken, is crushed after cleaning, drying, 30 mesh sieves are crossed, mixing obtains coarse powder, adds thick
The purified water that 8~10 times of powder weight soaks 30~60min, is subsequently placed in distiller, and progress microwave radiation technology steam distillation 1~
3h, collects distillate, divides after distillate cooling and take oil reservoir, oil reservoir is heated to 100 DEG C, sterilize 4~6min, produce volatile oil；
(2) by volatile oil made from step (1) and P-Cymene, rosemary oil, Rome chamomile essential oil, Ceylon cinnamon skin
Essential oil, bergamio, oak moss absolute, perilla alcohol, menthol and camellia seed oil are mixed, carry out low temperature homogenization 4~
6min, produces compound essential oil.
Further, the microwave radiation technology steam distillation in step (1) is specially：The first heating 6 in micro-wave oven~
10min, microwave power is 600W, and steam distillation is then carried out again and extracts 1~3h.
Further, the oil reservoir point is taken to be specially after the distillate cooling in step (1)：Using supercritical carbon dioxide fluid
Distillate after cooling is extracted, that is, divides taking-up oil reservoir, the condition of the supercritical carbon dioxide extraction is：Extraction
Pressure is 35MPa, and extraction temperature is 45 DEG C, and extraction time is 2h, and carbon dioxide flow is 30kg/h.
Further, low temperature homogenization is specially in step (2)：At 10 DEG C, homogenization pressure is 10~15MPa condition
4~6min of lower processing.
The application method for the compound essential oil that the present invention is provided is：Olein is applied to forehead, place between the eyebrows, double temples (temple)
And nostril periphery position, after can also being adsorbed, packing by the scraps of paper, used as Electrothermic steaming scented tea, while can also pass through Electrothermic steaming
Fragrant device heating is distributed.
Rome chamomile essential oil and Ceylon cinnamon peel essential oil in the compound essential oil are market product, are purchased from fragrant generation
(Shanghai) spices Co., Ltd of family.
Plants essential oil content in folium artemisiae argyi is low compared with Lysimachia foenum-graecum, Pon orange peel and the fruit of a cubeb litsea tree.Folium artemisiae argyi is first carried out molecule by the present invention
Distillation prepares P-Cymene, fully extracts the plants essential oil in folium artemisiae argyi.Then by P-Cymene and Lysimachia foenum-graecum, Pon orange peel
The volatile oil prepared with the fruit of a cubeb litsea tree through steam distillation is mixed, and plants essential oil is extracted to greatest extent, reduction is produced into
This.
Described compound essential oil extracts obtained volatile oil, P-Cymene, fan with Lysimachia foenum-graecum, Pon orange peel and fruit of a cubeb litsea tree three
Repeatedly sesame oil, Rome chamomile essential oil and Ceylon cinnamon peel essential oil are main active, and it is net to add bergamio, oak moss
Oil, perilla alcohol, menthol, with refreshing the mind well, fatigue-relieving, mood of releiving effect, and property is stable, and safety is stingless
Swash property, be adapted to be used for a long time.Wherein, oak moss absolute and perilla alcohol are that, compared with glop, property is stable, heat-resisting, with camellia seed
Oil, which is shared, can improve the stability of compound essential oil, and reduce volatilization.
Compared with prior art, advantage of the invention is that：
(1) compound essential oil that the present invention is provided is using natural plant volatile oil as main active, with significant infiltration
Absorbability, works rapid and evident in efficacy, can effectively keeping tensions down mood, mood of releiving, refresh the mind, fatigue-relieving.
(2) the compound essential oil property that the present invention is provided is stable, safe and non-stimulating property, is adapted to be used for a long time, and preparation technology
Simply, cost is relatively low.
Embodiment
The present invention is further described below by way of embodiment, but the present invention is not limited only to following examples.
It is prepared by the P-Cymene of embodiment 1
(1) by folium artemisiae argyi crush fill in supercritical carbon dioxide extraction kettle, set extraction kettle parameter as：Upper pressure
25MPa, push 48 DEG C of 27MPa, temperature；Set extraction-container parameter as：Pressure 5MPa, temperature 60 C, are passed through CO 2 fluid
Extraction, collects medicinal extract in extraction-container, stops when yield is up to 2.5%, produce folium artemisiae argyi medicinal extract；
(2) molecular distillation is carried out to folium artemisiae argyi medicinal extract made from step (1), is specially：
1. start setup parameter is 70 DEG C of jacket temperature, charging rate 130ML/H, evaporation layer temperature 70 C, condensate layer temperature
Spend 40 DEG C, below pressure 0.1Pa；
2. liquid nitrogen is poured into cold well；
3. the 70 DEG C of water-baths of folium artemisiae argyi medicinal extract are in a liquid state, pour feed well into, start charging after equipment reaches setup parameter；
4. light component bottle is collected into P-Cymene, and restructuring sub-bottle is collected into wax, and heel bottle is collected into steaming excess, produces Chinese mugwort
Leaf essential oil, P-Cymene yield about 15%.
It is prepared by the compound essential oil of embodiment 2
The preparing raw material that the compound essential oil of the embodiment of the present invention 2 includes following parts by weight is constituted：0.5 part of P-Cymene,
30 parts of rosemary oil, 25 parts of Lysimachia foenum-graecum, 25 parts of Pon orange peel, 20 parts of the fruit of a cubeb litsea tree, 2 parts of bergamio, 2 parts of oak moss absolute, purple perilla
15 parts of 5 parts of alcohol, 12 parts of menthol, 0.4 part of Rome chamomile essential oil, 0.1 part of Ceylon cinnamon peel essential oil and camellia seed oil.
Preparation method：
(1) Lysimachia foenum-graecum, Pon orange peel, the fruit of a cubeb litsea tree are taken, is crushed after cleaning, drying, 30 mesh sieves are crossed, mixing obtains coarse powder, adds thick
The purified water immersion 40min that 8 times of powder weight, is subsequently placed in distiller, 8min is heated in micro-wave oven, microwave power is
600W, then carries out steam distillation and extracts 3h, distillate is collected, using supercritical carbon dioxide fluid to the steaming after cooling again
Distillate is extracted, that is, divides taking-up oil reservoir, and the condition of the supercritical carbon dioxide extraction is：Extracting pressure is 35MPa,
Extraction temperature is 45 DEG C, and extraction time is 2h, and carbon dioxide flow is 30kg/h；
(2) by volatile oil made from step (1) and P-Cymene, rosemary oil, Rome chamomile essential oil, Ceylon cinnamon skin
Essential oil, bergamio, oak moss absolute, perilla alcohol, menthol and camellia seed oil are mixed, and at 10 DEG C, homogenization pressure is 10MPa's
Under the conditions of handle 5min, produce compound essential oil.
It is prepared by the compound essential oil of embodiment 3
The preparing raw material that the compound essential oil of the embodiment of the present invention 3 includes following parts by weight is constituted：0.1 part of P-Cymene,
25 parts of rosemary oil, 20 parts of Lysimachia foenum-graecum, 20 parts of Pon orange peel, 15 parts of the fruit of a cubeb litsea tree, 3 parts of bergamio, 1 part of oak moss absolute, purple perilla
10 parts of 8 parts of alcohol, 10 parts of menthol, 0.5 part of Rome chamomile essential oil, 0.2 part of Ceylon cinnamon peel essential oil and camellia seed oil.
Preparation method reference implementation example 2.
It is prepared by the compound essential oil of embodiment 4
The preparing raw material that the compound essential oil of the embodiment of the present invention 4 includes following parts by weight is constituted：0.6 part of P-Cymene,
35 parts of rosemary oil, 30 parts of Lysimachia foenum-graecum, 30 parts of Pon orange peel, 25 parts of the fruit of a cubeb litsea tree, bergamio 1,3 parts of oak moss absolute, perilla alcohol 2
Part, 16 parts of menthol, 0.1 part of Rome chamomile essential oil, 0.2 part of Ceylon cinnamon peel essential oil and 15 parts of camellia seed oil.
Preparation method reference implementation example 2.
It is prepared by the compound essential oil of comparative example 1
The preparing raw material that the compound essential oil of comparative example 1 of the present invention includes following parts by weight is constituted：0.5 part of P-Cymene,
30 parts of rosemary oil, 25 parts of Lysimachia foenum-graecum, 25 parts of Pon orange peel, 20 parts of the fruit of a cubeb litsea tree, 2 parts of bergamio, 2 parts of oak moss absolute, peppermint
15 parts of 12 parts of alcohol, 0.4 part of Rome chamomile essential oil, 0.1 part of Ceylon cinnamon peel essential oil and camellia seed oil.
Preparation method reference implementation example 2.The difference of this comparative example 1 and embodiment 2 is without perilla alcohol.
It is prepared by the compound essential oil of comparative example 2
The preparing raw material that the compound essential oil of comparative example 2 of the present invention includes following parts by weight is constituted：0.5 part of P-Cymene,
30 parts of rosemary oil, 25 parts of Lysimachia foenum-graecum, 25 parts of Pon orange peel, 20 parts of the fruit of a cubeb litsea tree, 2 parts of bergamio, 5 parts of perilla alcohol, menthol
15 parts of 12 parts, 0.4 part of Rome chamomile essential oil, 0.1 part of Ceylon cinnamon peel essential oil and camellia seed oil.
Preparation method reference implementation example 2.The difference of this comparative example 1 and embodiment 2 is without oak moss absolute.
Test example one, the detection of the volatility of compound essential oil
Volatility detection is carried out to compound essential oil made from the embodiment of the present invention 2 and comparative example 1,2, is specially：Take implementation
Each 3ml of compound essential oil made from example 2 and comparative example 1,2, it is open, it is placed in 35 DEG C of baking ovens, heating 5min, observation essential oil outward appearance,
Volume Changes, as a result see the table below 1.
The volatility testing result of the compound essential oil of table 1
| Group | Outward appearance | Volume Changes | Conclusion |
| Embodiment 2 | Uniform clear liquid | -0.4ml | It is stable |
| Comparative example 1 | Uniform clear liquid | -1.8ml | It is unstable |
| Comparative example 2 | Uniform clear liquid | -1.5ml | It is unstable |
As a result show, comparative example 1 and comparative example 2 are respectively without perilla alcohol and oak moss absolute, and obtained compound essential oil exists
Heated under the conditions of 35 DEG C, outward appearance does not have significant change, but volume reduces more significant, volatilization reduction, shows, perilla alcohol and oak moss are net
Oil is shared with wheat-germ oil, can improve compound essential oil volatile stabilizer, reduces volatilization.
Test example two, compound essential oil influence on mouse hypnotic effect caused by diphenhydramine
60 SPF grades of kunming mices are screened, body weight 20-25g is randomly divided into 6 groups, respectively model group, embodiment 2,3,4
Group, comparative example 1,2 groups, every group 10.Essential oil fragrance is carried out immediately after every mouse subcutaneous injection 0.1mg/kg diphenhydramine to smell
Hear, wherein, implementation 2,3,4 groups and comparative example 1,2 groups of mouse distinguish multiple made from smelling embodiment 2,3,4 and comparative example 1,2
Square essential oil, essential oil smelling amount is 5 μ l, and model group gives smelling distilled water, observes and record the number of elements (30min for the mouse that do not fall asleep
Do not fall asleep inside in terms of egersis), calculate egersis rate, latent time (injection diphenhydramine to fall asleep time), as a result see the table below
2。
The compound essential oil of table 2 influences on mouse hypnotic effect caused by diphenhydramine
Compared with model group,*P<0.05,**P<0.01；1 group is compared with comparative example,#P<0.05；2 groups are compared with comparative example
,▽P<0.05。
As a result show, compound essential oil made from the embodiment of the present invention 2,3,4 can significantly extend after mouse injection diphenhydramine
Into the time of sleep, and there are 2~3 mouse not fallen asleep in 30min, with 2 groups of best results of embodiment.And comparative example 1 and 2
Respectively without perilla alcohol and oak moss absolute, extend the decreased effectiveness of hypnagogic latency time, and the mouse not fallen asleep in 30min is only
Number is reduced.Result above shows that the compound essential oil that the present invention is provided has the effect that preferably refreshes the mind, and can effectively weaken benzene sea
Mouse hypnotic effect caused by Lamine.
Test example three, compound essential oil influence on Endurance
Screen 40 SPF grades of kunming mices, body weight 20-25g is randomly divided into 4 groups, respectively model group, 2 groups of embodiment,
Comparative example 1,2 groups, every group 10.Wherein, implement 2 groups and comparative example 1,2 groups of mouse difference smelling embodiment 2 and comparative example 1,
Compound essential oil made from 2, essential oil smelling amount is 5 μ l, and model group gives smelling distilled water, and each group mouse opens immediately after carrying out smelling
Toss about in bed rod fatigue test, specifically, mouse is placed on the tired instrument of transfer rod, rotating speed 20r/min is observed and recorded mouse on rod
Activity time (from transfer rod is put to time for falling down because of the fatigue), to evaluate the endurance of mouse.It the results are shown in Table 3.
Influence of the compound essential oil of table 3 to mouse roating bar tolerance
| Group | Activity time (min) on rod |
| Model group | 2.67±0.84 |
| Embodiment 2 | 7.12±1.76**#▽ |
| Comparative example 1 | 4.48±1.14* |
| Comparative example 2 | 4.62±1.02* |
Compared with model group,*P<0.05,**P<0.01；1 group is compared with comparative example,#P<0.05；2 groups are compared with comparative example
,▽P<0.05。
As a result show, compound essential oil made from the embodiment of the present invention 2 can significantly extend mouse activity on the tired instrument of transfer rod
Time, the roating bar tolerance of mouse is improved, with preferable antifatigue effect.And comparative example 1 and 2 respectively without perilla alcohol and
Oak moss absolute, shortens mouse time movable on the tired instrument of transfer rod, antifatigue decreased effectiveness.
It the above is only the preferred embodiment of the present invention, it is noted that above-mentioned preferred embodiment is not construed as pair
The limitation of the present invention, protection scope of the present invention should be defined by claim limited range.For the art
For those of ordinary skill, without departing from the spirit and scope of the present invention, some improvements and modifications can also be made, these change
Enter and retouch and also should be regarded as protection scope of the present invention.
Claims (9)
1. a kind of compound essential oil refreshed the mind, it is characterised in that the preparation that described compound essential oil includes following parts by weight is former
Material：0.1~0.8 part of P-Cymene, 25~35 parts of rosemary oil, 20~30 parts of Lysimachia foenum-graecum, 20~30 parts of Pon orange peel, the fruit of a cubeb litsea tree 15
~25 parts, 1~3 part of bergamio, 1~3 part of oak moss absolute, 2~8 parts of perilla alcohol, 10~16 parts of menthol and camellia seed oil
10~20 parts.
2. the compound essential oil according to claim 1 refreshed the mind, it is characterised in that described compound essential oil includes following
The preparing raw material of parts by weight：0.5 part of P-Cymene, 30 parts of rosemary oil, 25 parts of Lysimachia foenum-graecum, 25 parts of Pon orange peel, 20 parts of the fruit of a cubeb litsea tree,
15 parts of 2 parts of bergamio, 2 parts of oak moss absolute, 5 parts of perilla alcohol, 12 parts of menthol and camellia seed oil.
3. the compound essential oil according to claim 1 refreshed the mind, it is characterised in that described compound essential oil also include with
The preparing raw material of lower parts by weight：0.1~0.5 part of Rome chamomile essential oil, 0.05~0.2 part of Ceylon cinnamon peel essential oil.
4. the compound essential oil according to claim 3 refreshed the mind, it is characterised in that described compound essential oil includes following
The preparing raw material of parts by weight：0.5 part of P-Cymene, 30 parts of rosemary oil, 25 parts of Lysimachia foenum-graecum, 25 parts of Pon orange peel, 20 parts of the fruit of a cubeb litsea tree,
2 parts of bergamio, 2 parts of oak moss absolute, 5 parts of perilla alcohol, 12 parts of menthol, 0.4 part of Rome chamomile essential oil, Ceylon cinnamon skin
15 parts of 0.1 part of essential oil and camellia seed oil.
5. according to any described compound essential oils refreshed the mind of claim 1-4, it is characterised in that the system of the P-Cymene
Preparation Method comprises the following steps：
(1) by folium artemisiae argyi crush fill in supercritical carbon dioxide extraction kettle, set extraction kettle parameter as：Upper pressure 25MPa, under
Press 27MPa, 48 DEG C of temperature；Set extraction-container parameter as：Pressure 5MPa, temperature 60 C, are passed through CO 2 fluid extraction, in solution
Analyse kettle and collect medicinal extract, stop when yield is up to 2.5%, produce folium artemisiae argyi medicinal extract；
(2) molecular distillation is carried out to folium artemisiae argyi medicinal extract made from step (1), is specially：
1. start setup parameter is 70 DEG C of jacket temperature, charging rate 130ML/H, evaporation layer temperature 70 C, condensate layer temperature 40
DEG C, below pressure 0.1Pa；
2. liquid nitrogen is poured into cold well；
3. the 70 DEG C of water-baths of folium artemisiae argyi medicinal extract are in a liquid state, pour feed well into, start charging after equipment reaches setup parameter；
4. light component bottle is collected into P-Cymene, and restructuring sub-bottle is collected into wax, and heel bottle is collected into steaming excess, produces folium artemisiae argyi essence
Oil.
6. a kind of method for preparing the compound essential oil refreshed the mind as described in claim 1-5 is any, it is characterised in that including
Following steps：
(1) Lysimachia foenum-graecum, Pon orange peel, the fruit of a cubeb litsea tree are taken, is crushed after cleaning, drying, 30 mesh sieves are crossed, mixing obtains coarse powder, adds coarse powder weight
The purified water of 8~10 times of amount soaks 30~60min, is subsequently placed in distiller, carries out microwave radiation technology 1~3h of steam distillation,
Distillate is collected, divides after distillate cooling and takes oil reservoir, oil reservoir is heated to 100 DEG C, sterilize 4~6min, produce volatile oil；
(2) by volatile oil made from step (1) and P-Cymene, rosemary oil, Rome chamomile essential oil, Ceylon cinnamon skin essence
Oil, bergamio, oak moss absolute, perilla alcohol, menthol and camellia seed oil are mixed, and are carried out in low temperature 4~6min of homogenization,
Produce compound essential oil.
7. the preparation method of the compound essential oil according to claim 6 refreshed the mind, it is characterised in that in step (1)
Microwave radiation technology steam distillation is specially：6~10min is first heated in micro-wave oven, microwave power is 600W, and water-filling is then entered again
1~3h is extracted in steam distillation.
8. the preparation method of the compound essential oil according to claim 6 refreshed the mind, it is characterised in that in step (1)
The oil reservoir point is taken to be specially after distillate cooling：The distillate after cooling is extracted using supercritical carbon dioxide fluid, i.e.,
Divide and take out oil reservoir, the condition of the supercritical carbon dioxide extraction is：Extracting pressure is 35MPa, and extraction temperature is 45 DEG C,
Extraction time is 2h, and carbon dioxide flow is 30kg/h.
9. the preparation method of the compound essential oil according to claim 6 refreshed the mind, it is characterised in that low in step (2)
Warm homogenization is specially：At 10 DEG C, homogenization pressure is 4~6min of processing under conditions of 10~15MPa.
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| CN109181878A (en) * | 2018-09-29 | 2019-01-11 | 广州岐灵生物医药有限公司 | A kind of plants essential oil production method |
| CN109363969A (en) * | 2018-10-08 | 2019-02-22 | 广东暨晴生物医药科技有限公司 | A kind of method of comprehensive utilization of wormwood effective component |
| CN109363969B (en) * | 2018-10-08 | 2021-09-17 | 广东暨晴生物医药科技有限公司 | Comprehensive utilization method of effective components of wormwood |
| CN110804491A (en) * | 2019-10-28 | 2020-02-18 | 广东轻工职业技术学院 | Supercritical CO2Method for extracting and refining folium artemisiae argyi volatile oil by four-kettle separation |
| WO2021093459A1 (en) * | 2019-11-15 | 2021-05-20 | 广东暨晴生物医药科技有限公司 | Method for preparing mugwort leaf essential oil and by-products thereof by using supercritical co2 extraction and two-stage molecular distillation process |
| CN114712443A (en) * | 2021-11-30 | 2022-07-08 | 黄山荷琇生物科技有限公司 | Traditional Chinese medicine fermented composition, refreshing gel and preparation method thereof |
| CN114712443B (en) * | 2021-11-30 | 2023-06-16 | 黄山荷琇生物科技有限公司 | Traditional Chinese medicine fermentation composition, refreshing and restoring consciousness condensation and preparation method thereof |
| CN115813976A (en) * | 2021-12-31 | 2023-03-21 | 亿艾(河南)生物科技有限公司 | Nerve-soothing and relieving plant essential oil and application thereof |
| CN115813976B (en) * | 2021-12-31 | 2024-07-02 | 亿艾(河南)生物科技有限公司 | Plant essential oil for soothing nerves and application thereof |
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