CN109432318A - Compound essential oil, its application and compound essential oil product - Google Patents

Compound essential oil, its application and compound essential oil product Download PDF

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CN109432318A
CN109432318A CN201811534382.0A CN201811534382A CN109432318A CN 109432318 A CN109432318 A CN 109432318A CN 201811534382 A CN201811534382 A CN 201811534382A CN 109432318 A CN109432318 A CN 109432318A
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oil
parts
compound essential
essential oil
pelargonium
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CN109432318B (en
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刘月帅
易斌
肖艳皎
罗丽莲
韩雅慧
田军
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Beijing Scrianen Pharmaceutical Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
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    • A61K36/57Magnoliaceae (Magnolia family)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Abstract

The present invention relates to health protection with Chinese medicine technical fields, in particular to compound essential oil, its application and compound essential oil product.The compound essential oil includes the component of following volume parts: 1~10 part of pelargonium oil, 1~5 part of cedar oil, 1~3 part of jasmine oil, 1~3 part of lemon oil, 1~3 part of bergamot oil.The stoste of Pure natural plant essential oil is carried out reasonable compatibility by the present invention, and combines the ratio of science, plays synergistic effect, so that resulting compound essential oil relieves fatigue effect with good.

Description

Compound essential oil, its application and compound essential oil product
Technical field
The present invention relates to health protection with Chinese medicine technical fields, in particular to compound essential oil, its application and compound essential oil product.
Background technique
Modern due to some undesirable living habits, such as stay up late for a long time, diet is irregular, psychological pressure is big etc., warp The case where often having apathetic depressed, over fatigue on daytime generation.Especially as the variation of temperature, such as sultry summer, more Can make us feeling that head is murky, when facing heavy study and task, often stranded meaning is attacked, and then expression in the eyes lax, Lassitude, working efficiency naturally also straight line decline.Apathetic depressed, tired harm, is also manifested by the following aspects:
(1) accelerate aging
There is mind in prolonged fatigue and the apathetic depressed normal circulation that can destroy human endocrine and nervous system Through unbalance of system, accelerate the aging of human body, performance on the skin, be easy to appear skin quality is coarse, face partially Huang, color spot, poor flexibility, The problems such as lacking gloss.
(2) working efficiency is influenced
Tired, lassitude person sympathetic nerve is difficult to abundant excitement, therefore often will appear on daytime without spirit, head Phenomena such as confused brain rises, failure of memory, absent minded, slow in reacting, amnesia.And as the time increases, it is also possible to meeting Further result in the symptoms such as neurasthenia, insomnia.For common worker, lassitude will lead to the decline of working efficiency, But for high risk industries practitioner, fatigue and lassitude not only will result only in the decline of working efficiency, can also bring bigger Risk, cause unexpected, such as fatigue driving, the various accidents of fire explosion.
(3) resistance declines, in poor health
Human body is in the case where fatigue, lassitude, often due to lassitude, and then reduces all kinds of activities, for a long time with It is past, body rest and laws of motion can be destroyed, be easy to cause heartbeat disorders, it is nervous out of strength phenomena such as, the normal physiological week of people The normal reaction system of phase and human body is destroyed, and resistance is caused to decline, and then causes various diseases.
Therefore, in order to improve and overcome human-body fatigue, lassitude the phenomenon that, people have also carried out numerous replies and have arranged It applies, mainly there is following items:
(1) sleep of sufficient rule
For most people, at least to guarantee within one day that 6 sleeps more than hour, sufficient sleep can allow people to exist Keep abundant vigor daytime.
(2) coffee for drinking, tea etc. can be with stimulating beverages
Alkaloid in tealeaves and coffee can stimulate cranial nerve, form mental excitation, play refresh oneself, bracing work With.But it is noted that drinking in right amount, avoids largely drinking bring persistent psychotic excitement.
(3) suitable movement
The shortcomings that brains is often relatively awake after moderate exercise, and spirit is also at excited state, the method be compared with Hardly possible executes, especially for the people to bend over one's desk working for a long time.
(4) olfactory stimulation
By stimulating smell also to can achieve the effect to refresh the mind, using fragrant, cool Odor stimulation smell and skin, Promote to improve feeling tired out, that nerve is depressed, agastache rugosa water, floral water, cooling ointment, essential wind oil etc..But disadvantage is very much People is often not suitable with the special smell such as essential wind oil, cooling ointment, and these substances often have to skin when smearing it is certain Stimulation.
Essential oil is in the flower from plant, leaf, stem, root or fruit, passes through steam distillation, extrusion, cold-maceration or molten The volatile flavor of agent extraction method extraction.These volatile materials can enter body by nasal membrane tissue resorption, will interrogate Breath is directly sent to brain, by the limbic system of brain, adjusts the physiological function of mood and body.Therefore essential oil can strengthen physiology With the function of psychology, play calm and hypnosis, relieve fatigue, excitement is refreshed oneself, adjust mental status, antidepression, is alleviated psychology and is pressed Power repairs the functions such as nervous system.
Plants essential oil with high security, metabolism it is fast, in vivo without any residual, and application method simple and flexible multiplicity can The advantages that operation, to be alleviated suitable for exploitation with inhalation, fumigating system, massage etc. according to personal hobby and demand Tired product.But current selection or proportions of the essential oil due to component that relieve fatigue lacks science, relieves fatigue, refreshes oneself Restoring consciouness and less effective of inspiring enthusiasm, the fragrance of essential oil is also more dull, and crowd's acceptance is not high.
Summary of the invention
In view of this, the present invention provides compound essential oil, its application and compound essential oil products.The compound essential oil is by pure day The stoste of right plants essential oil carries out reasonable compatibility, and combines the ratio of science, plays synergistic effect, so that Resulting compound essential oil relieves fatigue effect with good.
In order to achieve the above-mentioned object of the invention, the present invention the following technical schemes are provided:
The present invention provides a kind of compound essential oil, the component including following volume parts:
1~10 part of pelargonium oil, 1~5 part of cedar oil, 1~3 part of jasmine oil, 1~3 part of lemon oil, bergamot oil 1~3 Part.
In Geranium Essential containing citronellol, citronellyl formate, loose alkene, gemic acid, Geraniol, terpinol, citral, Menthones and lot of trace mineral element can relieve pain, restrain antibacterial, the flat anxiety, dejected of comforting, moreover it is possible to improve mood, influence on kidney Gland cortex, allows mental recovery to balance, pressure of releiving.
Deodar essential oil has simple and elegant wooden faint scent, and containing cedrol, property is mild, there is anti-inflammatory, antibacterial, convergence, benefit Urine, softness, resolving sputum, the effect of killing fungus, while having good soothing effect to nervous and anxiety state.
Refined jasmine oil has graceful smell, and the gloomy mood that can releive inspires enthusiasm, promotes self-confidence, at the same can nurse with Improve dry skin, water shortage, excessively oil and sensitive situation.
Lemon can improve circulatory function, promote blood circulation, and enhance immune system, purify body, and improvement disappears Change system function, have the function of consoling and alleviating headache and migraines, refresh the mind, inspire enthusiasm, alleviates irritated, purification sky Gas.
Bergamot oil smell is fresh, simple and elegant, and similar orange and lemon, the slightly fragrance of a flower incorporate the abundant gas of fruity and the fragrance of a flower Taste is one of essential oil most-often used in perfume.It can pacify and improve, therefore be anxiety, dejected, when nervous Optimal selection, it to rouse oneself effect different from excitation, people can be helped to loosen.
Preferably, compound essential oil includes the component of following volume parts:
2~10 parts of pelargonium oil, 1~4 part of cedar oil, 1~3 part of jasmine oil, 1~3 part of lemon oil, bergamot oil 1~3 Part.
Preferably, compound essential oil includes the component of following volume parts:
2~10 parts of pelargonium oil, 2 parts of cedar oil, 1 part of jasmine oil, 1~2 part of lemon oil, 1~2 part of bergamot oil.
In an embodiment provided by the invention, compound essential oil includes the component of following volume parts:
10 parts of pelargonium oil, 2 parts of cedar oil, 1 part of jasmine oil, 2 parts of lemon oil, 1 part of bergamot oil.
In another embodiment provided by the invention, compound essential oil includes the component of following volume parts:
2 parts of pelargonium oil, 2 parts of cedar oil, 1 part of jasmine oil, 1 part of lemon oil, 2 parts of bergamot oil.
Preferably, compound essential oil further includes one or more of the component of following volume parts:
0.1~1 part of rosemary oil, 1~5 part of Clary Sage oil, 1~3 part of frankincense oil, 1~5 part of oil of grapefruit, sweet orange 1~5 part, 1~5 part of tangerine oil, 1~3 part of Flos micheliae Albae oil, 1~5 part of lemongrass oil of oil.
Rosemary oil main component is 2- borneol, is mainly used for weight-reducing, body shaping, chest enlarge, in body beautification essential oil, can improve language Obstacle in terms of speech, vision, hearing enhances attention, treats rheumatalgia, strengthens liver function, reduces blood glucose, facilitates artery The treatment of hardening helps the four limbs of paralysis to rejuvenate.Rosemary oil can make sanity with activating brain cell, enhance memory; Improve nervous mood, have pent-up feeling and drowsiness;People can be allowed alive, strengthen soul, have and improve and excitation.
Clary Sage oil can improve nervous, panic-stricken state, and parasympathetic nerve of releiving makes people warm joyous It is pleased, it is suitable for tired out, dejected and sad state, memory can be remarkably reinforced.
The fragrance of frankincense oil is warm pure wooden fragrance, and appears light fruity, can make that people's exaggerated respiration is allowed to become Slowly, feel to loosen and releive, make one to feel steady, mood improves and gentle, the negative feelings such as that help is releived is irritable, baffle, sadness Thread, and help meditation.
The main chemical component of oil of grapefruit is sobrerone or firpene, sabinene, laurene, limonene, geraniol, fragrant camphor tree Alcohol, citronellal, acetic acid certain herbaceous plants with big flowers ester and terpinenes or terpinene, can refresh oneself strongly, and can releive pressure, and disperse dejected feelings Thread allows people to refresh, and is the regulator of seasonal psychataxia.
Orange oil is one of contrastimulant essential oil, can be gentle neural, and decompression keeps body and mind pleasant, promotes vigor, Intense strain and pressure are expelled, insomnia caused by anxiety is improved.
The main component of tangerine oil is (R)-4-isopropenyl-1-methyl-1-cyclohexene, have eliminating the phlegm, cough-relieving, promote enterogastric peristalsis, promote digestive juice secretion, The effects of analgesia, dissolution gall stone and antiphlogistic antibacterial.Tangerine oil also has effects that keep human central nervous calm and subtract simultaneously The effect of light irritability.
The main component of Flos micheliae Albae oil is linalool, bergamio, dihydro linalool, benzyl carbinol, Cineole, oxidation virtue Camphor tree alcohol, terpinol, carypohyllene etc..Fragrance is pure and fresh, fresh deep and remote, faint scent band sweet tea, rhythm and gracefulness, fragrance are sent out thoroughly and not very stay length.It can be with Calm and relaxation nerve, eliminates nervous and palpitaition.
The main component of lemongrass oil is citral, myrcene, laurene, limonene etc., and people can be allowed to feel pure and fresh, had The effect of motivating, refreshing, to improving, spirit is quite helpful.
The effect of compound essential oil set of the invention a variety of essential oils, is mutually coordinated, complement each other, heighten the effect of a treatment in one, Make it have significantly relieve fatigue, refresh the mind, function of inspiring enthusiasm.Compound essential oil of the present invention is multiple for Pure natural plant essential oil With forming, without man-made additives such as preservative, essence, mineral greases, quality is pure, property is mild, using safe, non-stimulated Property.Compound essential oil of the present invention is compounded by a variety of essential oils, and fragrance fragrance is pleasant, mildly releives, and fragrance remaining time is long, is suitble to each Class crowd uses.
Preferably, the volume components number that above-mentioned compound essential oil further adds is as follows:
0.2~1 part of rosemary oil, 2~3 parts of Clary Sage oil, 1~2 part of frankincense oil, 1~4 part of oil of grapefruit, sweet orange 2~4 parts, 2~4 parts of tangerine oil, 1~3 part of Flos micheliae Albae oil, 1~5 part of lemongrass oil of oil.
It is highly preferred that the volume components number that compound essential oil further adds is as follows:
0.2~1 part of rosemary oil, 2~3 parts of Clary Sage oil, 1~2 part of frankincense oil, 1~4 part of oil of grapefruit, sweet orange 2~4 parts, 2~4 parts of tangerine oil, 2~3 parts of Flos micheliae Albae oil, 1~5 part of lemongrass oil of oil.
In an embodiment provided by the invention, the volume parts of each component in compound essential oil are as follows:
5 parts of pelargonium oil, 1 part of cedar oil, 1 part of jasmine oil, 3 parts of lemon oil, 3 parts of bergamot oil, 1 part of rosemary oil, fastly 3 parts of happy sage oil, 2 parts of frankincense oil, 4 parts of oil of grapefruit, 4 parts of orange oil, 4 parts of tangerine oil, 2 parts of Flos micheliae Albae oil, lemongrass oil 5 Part.
In another embodiment provided by the invention, the volume parts of each component in compound essential oil are as follows:
4 parts of pelargonium oil, 4 parts of cedar oil, 3 parts of jasmine oil, 2 parts of lemon oil, 2 parts of bergamot oil, 0.2 part of rosemary oil, 2 parts of Clary Sage oil, 1 part of frankincense oil, 1 part of oil of grapefruit, 2 parts of orange oil, 2 parts of tangerine oil, 3 parts of Flos micheliae Albae oil, lemon grass (Cymbopogon citratus) 1 part of oil.
Preferably, in compound essential oil each component volume parts are as follows:
1~10 part of pelargonium oil, 1~5 part of cedar oil, 1~3 part of jasmine oil, 1~3 part of lemon oil, bergamot oil 1~3 Part, 1~5 part of Clary Sage oil, 1~3 part of frankincense oil, 1~5 part of oil of grapefruit, 1~5 part of orange oil, 1~5 part of tangerine oil, 1~3 part of Flos micheliae Albae oil, 1~5 part of lemongrass oil.
Preferably, in compound essential oil each component volume parts are as follows:
2~10 parts of pelargonium oil, 1~4 part of cedar oil, 1~3 part of jasmine oil, 1~3 part of lemon oil, bergamot oil 1~3 Part, 2~3 parts of Clary Sage oil, 1~2 part of frankincense oil, 1~4 part of oil of grapefruit, 2~4 parts of orange oil, 2~4 parts of tangerine oil, 1~3 part of Flos micheliae Albae oil, 1~5 part of lemongrass oil.
Preferably, in compound essential oil each component volume parts are as follows:
1~10 part of pelargonium oil, 1~5 part of cedar oil, 1~3 part of jasmine oil, 1~3 part of lemon oil, bergamot oil 1~3 Part, 0.1~1 part of rosemary oil.
Preferably, in compound essential oil each component volume parts are as follows:
2~10 parts of pelargonium oil, 1~4 part of cedar oil, 1~3 part of jasmine oil, 1~3 part of lemon oil, bergamot oil 1~3 Part, 0.2~1 part of rosemary oil.
It is highly preferred that in compound essential oil each component volume parts are as follows:
2 parts of pelargonium oil, 2 parts of cedar oil, 1 part of jasmine oil, 1 part of lemon oil, 2 parts of bergamot oil, Clary Sage oil 2 Part, 1 part of frankincense oil, 2 parts of oil of grapefruit, 2 parts of orange oil, 2 parts of tangerine oil, 1 part, 2 parts of lemongrass oil of Flos micheliae Albae oil;
Or 10 parts of pelargonium oil, 2 parts of cedar oil, 1 part of jasmine oil, 2 parts of lemon oil, 1 part of bergamot oil, rosemary oil 0.5 part.
The present invention also provides above-mentioned compound essential oils to have effects that answering in the product for relieving fatigue, refreshing the mind in preparation With.
The present invention also provides the preparation methods of the compound essential oil, and each component in compound essential oil is mixed according to volume parts Uniformly.
The present invention also provides acceptable auxiliary on a kind of compound essential oil product, including above-mentioned compound essential oil and health care conduct and learning Material.
The present invention provides compound essential oil, its application and compound essential oil products.The compound essential oil includes following parts by volume Several components: 1~10 part of pelargonium oil, 1~5 part of cedar oil, 1~3 part of jasmine oil, 1~3 part of lemon oil, bergamot oil 1~3 Part.The technical effect that the present invention has are as follows:
(1) stoste of Pure natural plant essential oil is carried out reasonable compatibility by the present invention, and combines the ratio of science, is risen Synergistic effect is arrived, so that resulting compound essential oil relieves fatigue effect with good.
(2) Pure natural plant essential oil is used, essence, preservative, mineral grease is free of, has the function of antibacterial, sterilization, matter Pure, mild, safety, fragrance is pleasant, does not stimulate.
(3) it compounds compound essential oil: by compounding all kinds of plants essential oils, having the function that complement each other, heighten the effect of a treatment, improve Comfort, the safety and efficacy that human body uses.
(4) fragrance level is abundant: fragrance can gradually change as time went on when use, can bring to people different Experience and impression.
(5) relieve fatigue, effect of inspiring enthusiasm it is good, fragrant taste is not pungent, and crowd acceptance is high, can be applied directly to skin The compound essential oil of skin.
Specific embodiment
The invention discloses compound essential oil, its application and compound essential oil product, those skilled in the art can use for reference this Literary content, is suitably modified realization of process parameters.In particular, it should be pointed out that all similar substitutions and modifications are to art technology It is it will be apparent that they are considered as being included in the present invention for personnel.Method and application of the invention has passed through preferably Embodiment is described, related personnel obviously can not depart from the content of present invention, in spirit and scope to side as described herein Method and application are modified or appropriate changes and combinations, carry out implementation and application the technology of the present invention.
Raw materials used or auxiliary material can be by market in compound essential oil provided by the invention, its application and compound essential oil product It buys.
Below with reference to embodiment, the present invention is further explained:
Examples 1 to 6
The compound essential oil of the present embodiment, the component including volume parts as shown in the table.
1 Examples 1 to 6 compound essential oil formula of table
Comparative example 1~5:
2 comparative example of table, 1~5 compound essential oil formula
Component Comparative example 1 Comparative example 2 Comparative example 3 Comparative example 4 Comparative example 5
Pelargonium oil 0 2 15 0 0
Cedar oil 2 2 2 0 0
Jasmine oil 0 1 1 0 0
Lemon oil 2 1 2 0 0
Bergamot oil 1 0 1 0 0
Rosemary oil 0 0 0 0 0.5
Clary Sage oil 0 0 0 2 2
Frankincense oil 0 0 0 1 1
Oil of grapefruit 0 0 0 2 2
Orange oil 0 0 0 2 2
Tangerine oil 0 0 0 2 2
Flos micheliae Albae oil 0 0 0 1 1
Lemongrass oil 0 0 0 2 2
Test example 1
In order to further prove that advantages of the present invention, the present invention provide the compliance test result of Examples 1 to 6 and comparative example 1~5 Data.
(1) confirmatory experiment of the compound essential oil of Examples 1 to 6 and comparative example 1~5 to mouse anti-reflecting fatigue ability.
(1) experimental animal
Choosing SPF grades of kunming mices is subjects, half male and half female, 18~20g of weight.After adaptable fed 7 days, at random Mouse is divided into a blank control group, 6 embodiment groups and 5 comparative example groups, mouse is put into crisper carry out respectively Wen Xiang, small-sized heating atomization device built in crisper.
(2) experimental method
1 group is blank control group, and heating atomization sucks distilled water, and each dosage 100 μ L, each respiratory time 30min connect Continuous 30d;
2~7 groups are Examples 1 to 6 group, and heating atomization sucks compound essential oil described in Examples 1 to 6, each dosage 100 μ L, each respiratory time 30min, continuous 30d;
8~12 groups are 1~5 group of comparative example, and heating atomization sucks compound essential oil described in comparative example 1~5, each dosage 100 μ L, each respiratory time 30min, continuous 30d.
Tested after news perfume 30min in the 30th day, observation the mice burden swimming time, serum urea nitrogen, hepatic glycogen and Blood lactase acid result.
The mice burden swimming time: after last hears perfume 30min, by the sheet lead of 5% weight of mouse tail root load, it is placed in trip Swimming case went swimming, depth of water 30cm, 25 DEG C ± 1 DEG C of water temperature, record mouse is since, to the dead time, as mouse bears a heavy burden swimming Swimming time.
Serum urea nitrogen: after last hears perfume 30min, mouse not swimming with a load attached to the body 90min in 30 DEG C ± 1 DEG C of temperature of water, Eyeball, which is pulled out, after rest 60min adopts whole blood, serum urea nitrogen is measured with diacetyl monoxime method.
Hepatic glycogen: after last hears perfume 30min, mouse is placed in not swimming with a load attached to the body 90min in 30 DEG C ± 1 DEG C of water, then Mouse is put to death, liver is taken to be blotted after physiological saline rinses with filter paper, hepatic glycogen content is measured using anthrone method.
Blood lactase acid: last is taken a blood sample after hearing perfume 30min, then the sheet lead of the negative weight 4% of mouse, in 30 DEG C ± 1 DEG C of water Swim 10min, takes a blood sample after trip, takes a blood sample again immediately after rest 20min, measures Serum lactic acid content with Plasma lactate instrument.
(3) data processing
Measurement data is indicated with mean ± standard deviation, carries out data processing using one-way analysis of variance method.P < 0.05 Indicate statistically significant.
(4) experimental result
Influence (water temperature 25 DEG C) of the different group compound essential oils of table 3 to the mice burden swimming time
Note: shoulder mark * indicates embodiment, comparative example each group compared with blank control group with significant difference, P < 0.05; Same column shoulder marking-up female (a, b, c, d, e, f, g, h, i, j, k) indicates to be compared between embodiment and comparative example difference group, indicates not Indicate that there is significant difference, P < 0.05 with letter.
Influence of the different group compound essential oils of table 4 to serum urea nitrogen after mouse movement
Group Number of cases/only Serum urea nitrogen (mg/dL)
Blank control group 10 67.0±6.7*a
Example 1 group 10 37.7±6.5*ef
2 groups of embodiment 10 41.2±7.3*de
3 groups of embodiment 10 27.1±6.9*f
4 groups of embodiment 10 31.1±9.0*ef
5 groups of embodiment 10 33.4±11.4*ef
6 groups of embodiment 10 35.9±9.2*ef
1 group of comparative example 10 52.5±7.1*bc
2 groups of comparative example 10 49.7±7.6*cd
3 groups of comparative example 10 47.8±11.6*cd
4 groups of comparative example 10 60.5±9.3*ab
5 groups of comparative example 10 55.1±9.0*bc
Note: shoulder mark * indicates embodiment, comparative example each group compared with blank control group with significant difference, P < 0.05; Same column shoulder marking-up female (a, b, c, d, e, f) indicates to be compared between embodiment and comparative example difference group, and indicating different letters indicates With significant difference, P < 0.05.
Influence of the different group compound essential oils of table 5 to mouse hepatic glycogen content
Group Number of cases/only Hepatic glycogen (mg/100g liver)
Blank control group 10 353.2±6.5*l
Example 1 group 10 601.0±17.6*e
2 groups of embodiment 10 552.5±15.1*f
3 groups of embodiment 10 804.8±10.5*a
4 groups of embodiment 10 751.7±11.9*b
5 groups of embodiment 10 702.8±15.0*c
6 groups of embodiment 10 652.5±15.1*d
1 group of comparative example 10 441.0±25.5*i
2 groups of comparative example 10 474.5±19.6*h
3 groups of comparative example 10 504.5±19.6*g
4 groups of comparative example 10 388.0±22.6*k
5 groups of comparative example 10 416.0±21.8*j
Note: shoulder mark * indicates embodiment, comparative example each group compared with blank control group with significant difference, P < 0.05; Same column shoulder marking-up female (a, b, c, d, e, f, g, h, i, j, k, l) indicates to be compared between embodiment and comparative example difference group, indicates Different letters indicate there is significant difference, P < 0.05.
Influence of the different group compound essential oils of table 6 to blood lactase acid value before and after mouse movement
Note: shoulder mark * indicates embodiment, comparative example each group compared with blank control group with significant difference, P < 0.05; Same column shoulder marking-up female (a, b, c, d, e, f, g) indicates to be compared between embodiment and comparative example difference group, indicates different alphabets Show with significant difference, P < 0.05.
By above-mentioned test it is found that Examples 1 to 6 group and 1~5 group of comparative example are compared with blank control group, the weight bearing of mouse Swimming time and hepatic glycogen content increased, and have significant difference (P < 0.05);Serum urea nitrogen, movement front and back Blood lactase acid value is declined, and has significant difference (P < 0.05).
The experimental results showed that the essential oil of Examples 1 to 6 and comparative example 1~5 all has and certain relieves fatigue effect.Implement 1~6 group of example with 1~5 group of comparative example of comparison among groups the result shows that, walking weight load, the hepatic glycogen of Examples 1 to 6 group contain Amount is significantly greater than 1~5 group of comparative example, and serum urea nitrogen, movement front and back blood lactase acid value are significantly less than 1~5 group of comparative example, wherein Optimal effect is 3 groups of embodiment.As a result prompt, pelargonium oil, cedar oil, jasmine oil, lemon oil, between bergamot oil with certain Ratio be combined, can play synergistic function, obtain preferable antifatigue effect, and further add rosemary One of oil, Clary Sage oil, frankincense oil, oil of grapefruit, orange oil, tangerine oil, Flos micheliae Albae oil, lemongrass oil are more Kind, it can be further improved the effect of composition.
(2) the compound essential oil fragrance acceptance of Examples 1 to 6 and comparative example 1~5 is investigated
Please 50 experienced professionals form evaluation groups, to compound described in Examples 1 to 6 and comparative example 1~5 Essential oil fragrance is evaluated, and evaluation result is as follows:
Acceptance demographics of 7 crowd of table to different essential oil fragrance
Group It is satisfied Generally It is dissatisfied
Example 1 group 42 5 3
2 groups of embodiment 41 6 3
3 groups of embodiment 46 3 1
4 groups of embodiment 45 4 1
5 groups of embodiment 44 5 1
6 groups of embodiment 44 4 2
1 group of comparative example 39 7 4
2 groups of comparative example 35 10 5
3 groups of comparative example 37 8 5
4 groups of comparative example 33 11 6
5 groups of comparative example 36 8 6
Acceptance proportion of 8 crowd of table to different essential oil fragrance
Group It is satisfied Generally It is dissatisfied
Example 1 group 84% 10% 6%
2 groups of embodiment 82% 12% 6%
3 groups of embodiment 92% 6% 2%
4 groups of embodiment 90% 8% 2%
5 groups of embodiment 88% 10% 2%
6 groups of embodiment 88% 8% 4%
1 group of comparative example 78% 14% 8%
2 groups of comparative example 70% 20% 10%
3 groups of comparative example 74% 16% 10%
4 groups of comparative example 66% 22% 12%
5 groups of comparative example 72% 16% 12%
Above-mentioned test result shows crowd to the acceptance of various combination essential oil fragrance, from dissatisfaction as can be seen that The dissatisfaction of embodiment is below comparative example, it can be seen that, the fragrance acceptance of each embodiment is above comparative example, wherein Satisfaction is up to embodiment 3.
Test example 2
In order to further prove the advantage of compound essential oil of the invention relative to single essential oil, the present invention provide embodiment 1, Pelargonium oil, cedar oil, jasmine oil, lemon oil, bergamot oil are to the confirmatory experiment of mouse anti-reflecting fatigue ability.
(1) experimental animal
Choosing SPF grades of kunming mices is subjects, half male and half female, 18~20g of weight.After adaptable fed 7 days, at random Mouse is divided into 1 embodiment group and 5 single essential oil groups, mouse is put into carry out hearing perfume in crisper respectively, in crisper Set small-sized heating atomization device.
(2) experimental method
Example 1 group, heating atomization suck compound essential oil described in embodiment 1, each 100 μ L of dosage, every time when sucking Between 30min, continuous 30d;
Single essential oil group, the single essential oil of heating atomization sucking, each dosage 100 μ L, each respiratory time 30min, continuously 30d。
Tested after news perfume 30min in the 30th day, observation the mice burden swimming time, serum urea nitrogen, hepatic glycogen and Blood lactase acid result.
The mice burden swimming time: after last hears perfume 30min, by the sheet lead of 5% weight of mouse tail root load, it is placed in trip Swimming case went swimming, depth of water 30cm, 25 DEG C ± 1 DEG C of water temperature, record mouse is since, to the dead time, as mouse bears a heavy burden swimming Swimming time.
Serum urea nitrogen: after last hears perfume 30min, mouse not swimming with a load attached to the body 90min in 30 DEG C ± 1 DEG C of temperature of water, Eyeball, which is pulled out, after rest 60min adopts whole blood, serum urea nitrogen is measured with diacetyl monoxime method.
Hepatic glycogen: after last hears perfume 30min, mouse is placed in not swimming with a load attached to the body 90min in 30 DEG C ± 1 DEG C of water, then Mouse is put to death, liver is taken to be blotted after physiological saline rinses with filter paper, hepatic glycogen content is measured using anthrone method.
Blood lactase acid: last is taken a blood sample after hearing perfume 30min, then the sheet lead of the negative weight 4% of mouse, in 30 DEG C ± 1 DEG C of water Swim 10min, takes a blood sample after trip, takes a blood sample again immediately after rest 20min, measures Serum lactic acid content with Plasma lactate instrument.
(3) data processing
Measurement data is indicated with mean ± standard deviation, carries out data processing using one-way analysis of variance method.P < 0.05 Indicate statistically significant.
(4) experimental result
The influence (25 DEG C of water temperature) of 9 compound essential oil of table or single essential oil to the mice burden swimming time
Group Number of cases/only Swimming time/S
Example 1 group 10 552.1±8.2*a
Pelargonium oil group 10 402.3±6.3*c
Cedar oil group 10 386±7.9*e
Jasmine oil group 10 396±10.1*d
Lemon oil group 10 378±8.5*f
Bergamot oil group 10 409±9.4*b
Note: shoulder mark * indicates embodiment, comparative example each group compared with blank control group with significant difference, P < 0.05; Same column shoulder marking-up female (a, b, c, d, e, f) indicates to be compared between embodiment and comparative example difference group, and indicating different letters indicates With significant difference, P < 0.05.
The influence of 10 compound essential oil of table or single essential oil to serum urea nitrogen after mouse movement
Group Number of cases/only Serum urea nitrogen (mg/dL)
Example 1 group 10 37.7±6.5*d
Pelargonium oil group 10 63.2±5.3*abc
Cedar oil group 10 64.9±7.9*ab
Jasmine oil group 10 64.1±8.4*abc
Lemon oil group 10 65.3±7.6*ab
Bergamot oil group 10 61.5±5.1*bc
Note: shoulder mark * indicates embodiment, comparative example each group compared with blank control group with significant difference, P < 0.05; Same column shoulder marking-up female (a, b, c, d) indicates to be compared between embodiment and comparative example difference group, and indicating different letters indicates have Significant difference, P < 0.05.
The influence of 11 compound essential oil of table or single essential oil to mouse hepatic glycogen content
Group Number of cases/only Hepatic glycogen (mg/100g liver)
Example 1 group 10 601.0±17.6*a
Pelargonium oil group 10 374±21.3*cd
Cedar oil group 10 361±27.6*de
Jasmine oil group 10 368±18.9*de
Lemon oil group 10 354±15.4*e
Bergamot oil group 10 385±26.7*bc
Note: shoulder mark * indicates embodiment, comparative example each group compared with blank control group with significant difference, P < 0.05; Same column shoulder marking-up female (a, b, c, d, e) indicates to be compared between embodiment and comparative example difference group, and indicating different letters indicates tool There are significant difference, P < 0.05.
The influence of 12 compound essential oil of table or single essential oil to blood lactase acid value before and after mouse movement
Note: shoulder mark * indicates embodiment, comparative example each group compared with blank control group with significant difference, P < 0.05; Same column shoulder marking-up female (a, b, c, d, e) indicates to be compared between embodiment and comparative example difference group, and indicating different letters indicates tool There are significant difference, P < 0.05.
The experimental results showed that 1 compound essential oil of embodiment and single essential oil all have and certain relieve fatigue effect.Embodiment 1 Group with the comparison among groups of single essential oil group the result shows that, walking weight load, the hepatic glycogen content of example 1 group are significantly greater than each Single essential oil group, serum urea nitrogen, movement front and back blood lactase acid value are significantly less than each single essential oil group.As a result it prompts, fish pelargonium Oil, jasmine oil, lemon oil, is combined between bergamot oil cedar oil in certain proportion, can play synergistic work With the preferable antifatigue effect of acquirement.
The above is only a preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art For member, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications are also answered It is considered as protection scope of the present invention.

Claims (10)

1. a kind of compound essential oil, which is characterized in that the component including following volume parts:
1~10 part of pelargonium oil, 1~5 part of cedar oil, 1~3 part of jasmine oil, 1~3 part of lemon oil, 1~3 part of bergamot oil.
2. compound essential oil according to claim 1, which is characterized in that the component including following volume parts:
2~10 parts of pelargonium oil, 1~4 part of cedar oil, 1~3 part of jasmine oil, 1~3 part of lemon oil, 1~3 part of bergamot oil.
3. compound essential oil according to claim 1, which is characterized in that the component including following volume parts:
2~10 parts of pelargonium oil, 2 parts of cedar oil, 1 part of jasmine oil, 1~2 part of lemon oil, 1~2 part of bergamot oil.
4. compound essential oil according to claim 1, which is characterized in that the compound essential oil further includes following volume parts One or more of component:
0.1~1 part of rosemary oil, 1~5 part of Clary Sage oil, 1~3 part of frankincense oil, 1~5 part of oil of grapefruit, orange oil 1~ 5 parts, 1~5 part of tangerine oil, 1~3 part of Flos micheliae Albae oil, 1~5 part of lemongrass oil.
5. compound essential oil according to claim 4, which is characterized in that the volume parts of each component in the compound essential oil Are as follows:
1~10 part of pelargonium oil, 1~5 part of cedar oil, 1~3 part of jasmine oil, 1~3 part of lemon oil, 1~3 part of bergamot oil, fastly 1~5 part of happy sage oil, 1~3 part of frankincense oil, 1~5 part of oil of grapefruit, 1~5 part of orange oil, 1~5 part of tangerine oil, Flos micheliae Albae 1~3 part, 1~5 part of lemongrass oil of oil.
6. compound essential oil according to claim 4, which is characterized in that the volume parts of each component in the compound essential oil Are as follows:
1~10 part of pelargonium oil, 1~5 part of cedar oil, 1~3 part of jasmine oil, 1~3 part of lemon oil, 1~3 part of bergamot oil, fan Repeatedly 0.1~1 part of sesame oil.
7. compound essential oil according to claim 4, which is characterized in that the volume parts of each component in the compound essential oil Are as follows:
2 parts of pelargonium oil, 2 parts of cedar oil, 1 part of jasmine oil, 1 part of lemon oil, 2 parts of bergamot oil, 2 parts of Clary Sage oil, cream 1 part of sesame oil, 2 parts of oil of grapefruit, 2 parts of orange oil, 2 parts of tangerine oil, 1 part, 2 parts of lemongrass oil of Flos micheliae Albae oil;
Or 10 parts of pelargonium oil, 2 parts of cedar oil, 1 part of jasmine oil, 2 parts of lemon oil, 1 part of bergamot oil, 0.5 part of rosemary oil.
8. compound essential oil described in any one of claims 1 to 7 has effects that in the product for relieving fatigue, refreshing the mind in preparation Application.
9. the preparation method of compound essential oil described in any one of claims 1 to 7, which is characterized in that by each group in compound essential oil Divide and is uniformly mixed according to volume parts.
10. a kind of compound essential oil product, which is characterized in that including compound essential oil described in any one of claims 1 to 7 and health care Acceptable auxiliary material in conduct and learning.
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