CN110279637A - A kind of wormwood bath foam - Google Patents
A kind of wormwood bath foam Download PDFInfo
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- CN110279637A CN110279637A CN201910567761.8A CN201910567761A CN110279637A CN 110279637 A CN110279637 A CN 110279637A CN 201910567761 A CN201910567761 A CN 201910567761A CN 110279637 A CN110279637 A CN 110279637A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/424—Gynostemma
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/483—Gleditsia (locust)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
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- A—HUMAN NECESSITIES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
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- A61K36/88—Liliopsida (monocotyledons)
- A61K36/904—Stemonaceae (Stemona family), e.g. croomia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61Q19/10—Washing or bathing preparations
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Abstract
The invention belongs to technical field of daily necessities, especially a kind of wormwood bath foam, the component including following parts by weight: 24-50 parts of wormwood stostes, 10-15 portions of Chinese honey locusts, 8-12 parts of wild chrysanthemums, the 6-10 parts of tubers of stemona, 4-6 portions of sweet wormwoods, 6-10 portions of roses, 4-6 portions of radix saposhnikoviaes, 2-4 portions of gynostemma pentaphylla, 8-12 parts of smilax extracting solutions.Shower liquid product prepared by the present invention is made of to select Chinese medicine, is not added with any chemicals, has no toxic side effect, and no pollution to the environment;10 taste Chinese medicines coordinate arrange in pairs or groups made of shower liquid product play the role of temperature through dehumidifying cold dispelling, killing pests and suppressing bacteria is antipruritic, moisturizing beauty treatment of refreshing oneself, it can relieve fatigue, improve spirit, adjust smooth channels and collaterals, it dehumidifies antibacterial, pathogenic skin bacterium/fungies a variety of to Escherichia coli, staphylococcus aureus, shigella dysenteriae, acrothesium floccosum etc. have apparent bacteriostasis, have good preventive and therapeutic effect to itch caused by all kinds of pathogenic bacteria.
Description
Technical field
The invention belongs to technical field of daily necessities, especially a kind of wormwood bath foam.
Background technique
Wormwood also known as holds back grass, fragrant Chinese mugwort, Chinese mugwort, argy wormwood, moxibustion grass, moxa etc., composite family herbaceos perennial.Contain in wormwood
It is the substances such as phellandrene, Cadinene, thujanol, linalool, artemetine, wormwood be peaceful, and there is strong fragrance and temperature
Through, dry, cold dispelling, hemostasis, anti-inflammatory, relieving asthma, cough-relieving, miscarriage prevention, antiallergy the effects of, be usually used in treating gynaecology's disease of deficient cold type
Suffer from, senile chronic bronchitis and, asthma and cold of insufficiency type and stomachache etc..
With the raising of modern life level, people increasingly pay close attention to the effect of bath foam health care, more and more Chinese medicines
Bath foam occurs in people's daily life, such as wormwood shower cream, honeysuckle shower cream, has antipruritic, humidification, whitening etc.
Effect;These Chinese medicinal bathing lotions are mostly mixed with the Chinese medicine extract of each functional form with chemical substances such as surfactant, thickeners
It forms, still there is certain side effect, and health-care effect possessed by bath foam is usually the superposition of various Chinese medicines, is not had
In view of mutual collocation coordination and synergy or inhibiting effect.Such as application No. is the patent disclosures of CN201810104042.8
A kind of script Chinese medicinal plant nutritional preparation cleaning solution production technology, take wormwood, wild chrysanthemum, Jasmine, rose, sweet osmanthus,
Rhizoma acori graminei, cloves, wrinkled giant hyssop, purple perilla, lavender, peppermint, leaf of Cortex cinnamomi camphorae, campanulaceae (pericarp), shaddock leaf (pericarp), Chinese weeping cypress leaf (seed),
And ginger, ginkgo leaf (fruit), the fleece-flower root, ganoderma lucidum etc. take its color and fragrance and nutrition to make primary colors original flavouring agent;Take green grass green
The green juice of the leaf of bamboo or green wheat seedling makees green color source;Production technology is production process: 1, workshop boils Chinese medicine decoction of medicinal ingredients by hand
" the script Chinese medicinal plant nutritional preparation " that method obtains " color, smell and taste " is spare;2, plant is saponified with multiple additives such as potassium hydroxide
The saponification agent of animal fat is spare;3, by both above after mixing according to the different Chinese medicinal plants for obtaining assorted each perfume of addition
Nutritional preparation cleaning solution.The patent is that the cleaning solutions such as bath foam are made in the extract of the substances such as wormwood and chemical saponification agent, is changed
The utilization for learning class saponification agent causes cleaning solution to there are problems that polluting environment, have side effect.
Summary of the invention
In order to solve the above technical problems existing in the prior art, researcher of the present invention passes through the research and development of many years and faces
Bed experiment, with numerous Chinese medicines carry out screening study, and to medicinal material treatment process, specific dosage form preparation method also carry out it is different because
The impact analysis of element proposes wormwood bath foams a kind of natural and with excellent health functions, particular by following technology
What scheme was realized:
A kind of wormwood bath foam, the component including following parts by weight: 24-50 parts of wormwood stostes, 10-15 parts of Chinese honey locusts, 8-12
Part wild chrysanthemum, the 6-10 parts of tubers of stemona, 4-6 portions of sweet wormwoods, 6-10 portions of roses, 4-6 portions of radix saposhnikoviaes, 2-4 portions of gynostemma pentaphylla, 8-12 portions of smilaxs mention
Take liquid.
Preferably, the wormwood bath foam, the component including following parts by weight: 42 parts of wormwood stostes, 12 parts of Chinese honey locusts, 10
Part wild chrysanthemum, 6 parts of tubers of stemona, 4 portions of sweet wormwoods, 8 portions of roses, 5 parts of radix saposhnikoviaes, 3 portions of gynostemma pentaphylla, 10 parts of smilax extracting solutions.
Preferably, after smilax is crushed, 12 times of 80% ethyl alcohol the preparation of the smilax extracting solution: is added at 70 DEG C
Lower refluxing extraction 2 times, extracts 40min every time, merges 2 times and extracts obtained filtrate, and ethyl alcohol is recovered under reduced pressure to get smilax extraction
Liquid.
Preferably, the preparation of the wormwood stoste: after wormwood is smashed to pieces, 10 times of water soaked overnight is added, centrifugation takes
Clear liquid to obtain the final product.
Preferably, the preparation method of the wormwood bath foam, includes the following steps:
(1) each component is weighed by the above parts by weight, by the tuber of stemona, sweet wormwood, radix saposhnikoviae, gynostemma pentaphylla, Chinese honey locust co-grinding, in acquisition
Medicinal powder is spare, spare;
(2) it with after steam treatment traditional Chinese medicine powder 5-6min, is cooled to room temperature, adds rose, wild chrysanthemum mixing, continue with steaming
Vapour handles 1min or so, cooling, spare;
(3) wormwood stoste is uniformly mixed with smilax extracting solution, step (2) hybrid medicine obtained is added in 30-
After impregnating 4-5h at 35 DEG C, filtering obtains filtrate and filter residue, spare;
(4) alcohol reflux for taking filter residue that 8-10 times of weight is added extracts 2-3 times, each 1-1.5h, merges ethanol extract,
Ethyl alcohol is recycled, the extracting solution obtained is spare;
(5) filtrate is uniformly mixed with extracting solution, is heated to 40-45 DEG C of insulated and stirred 25-30min, is again heated to 50-60
DEG C insulated and stirred 6-8min, the bath foam finished product obtained after cooling.
Preferably, the traditional Chinese medicine powder is 60-80 mesh.The partial size of traditional Chinese medicine powder is maintained at 60-80 mesh, portion therein can be inhibited
Point effective component is destroyed during the extraction process, while can be reduced the impurity in extracting solution again, enable made of bath foam protect
Good stability is held,
Preferably, the temperature of the steam is 80-100 DEG C.Dry medicinal powder can be made to become with steam treated herb powder
It is soft, structure is more loose, be added to wormwood stoste, drug effect can be improved with abundant interaction in smilax extracting solution;It steams simultaneously
Vapour processing can remove in medicinal herbs native taste and herbaceous taste, can be reduced the peculiar smell in bath foam, make its good fragrance of holding.
Preferably, the step (4), concentration of alcohol 65-70%.
Preferably, the olive emulsifier or carragheen of its quality 3%-4% is added in the wormwood bath foam finished product, can
Wormwood bath oil is made.
The Chinese medicine that the present invention selects has effects that following:
Wormwood: it Wen Jing, dries, cold dispelling, hemostasis, anti-inflammatory, relieving asthma, cough-relieving, miscarriage prevention, antiallergy.
Chinese honey locust: eliminating the phlegm is sensible, antibechic diuresis, detumescence and apocenosis, desinsection control tinea.
Wild chrysanthemum: dispelling wind and heat from the body, subdhing swelling and detoxicating;Furunculosis carbuncle swells, abscess of throat, wind-fire red eye, headache and dizziness etc. can be treated
Disease.
The tuber of stemona: desinsection, antipruritic, delousing.
Sweet wormwood: clearind deficient heat removes hectic fever due to yin, hot summer weather is solved, the effect of preventing malaria, removing jaundice;It is usually used in warm evil impairment of yin, night fever abating at dawn, yin
It shoots without hitting the target heat, hectic fever due to yin labor heat, summer-heat evil fever, malaria fever and chills, the treatment of the illnesss such as jaundice with damp-heat pathogen.
Rose: qi-regulating, promoting blood circulation, Thyme Extract;Cure mainly irregular menstruation, traumatic injury, irritability stomachache, too fat to move pain of cream etc.
Disease;Soft liver is waken up stomach, promoting blood circulation of having a respite, beautifying face and moistering lotion, makes us refreshing refreshing.
Radix saposhnikoviae: having the effect of sweating, eliminating the phlegm, wind dispelling, deliver, ease pain, for curing cold, having a headache, whole body arthralgia, nerve
The diseases such as pain.
Gynostemma pentaphylla: asthenia;Nephrasthenia emission;Leukopenia;Hyperlipidemia;Virus hepatitis;Chronic gastroenteritis;
Chronic bronchitis.
Smilax: limbs muscular constricture, arthralgia and myalgia;Damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle swells, scrofula, scabies.
Compared with prior art, the beneficial effects of the present invention are:
The present invention selects wormwood, rose collocation to use, and has warming and activating meridian, the benefits of invigorating blood circulation of having a respite;Chinese honey locust, wild chrysanthemum, the tuber of stemona,
Smilax collocation uses, and has that eliminating the phlegm is sensible, desinsection controls the benefits of tinea is antibacterial, to Escherichia coli, staphylococcus aureus, dysentery bar
A variety of pathogenic skin bacterium/fungies such as bacterium, acrothesium floccosum have apparent bacteriostasis;Sweet wormwood, radix saposhnikoviae, wild chrysanthemum are taken
With use, there is the benefits of scattered body waste heat;Gynostemma pentaphylla, wormwood collocation use, and have the effect of help, relieve fatigue.All medicines share, altogether
Play temperature through dehumidifying cold dispelling, killing pests and suppressing bacteria is antipruritic, the function for moisturizing beauty treatment of refreshing oneself.Moreover, shower liquid product selects pure Chinese medicine material to be made,
Any chemicals are not added with, are had no toxic side effect, no pollution to the environment.
Specific embodiment
It is limited below with reference to specific embodiment technical solution of the present invention is further, but claimed
Range is not only limited to made description.
1 bath foam of embodiment
Component: 24 parts of wormwood stostes, 10 portions of Chinese honey locusts, 8 parts of wild chrysanthemums, 6 parts of tubers of stemona, 4 portions of sweet wormwoods, 6 portions of roses, 4 parts of radix saposhnikoviaes,
2 portions of gynostemma pentaphylla, 8 parts of smilax extracting solutions.
The preparation of the smilax extracting solution: after smilax is crushed, 12 times of 80% ethyl alcohol is added and flows back at 70 DEG C
It extracts 2 times, extracts 40min every time, merge 2 times and extract obtained filtrate, ethyl alcohol is recovered under reduced pressure to get smilax extracting solution.
The preparation of the wormwood stoste: after wormwood is smashed to pieces, 10 times of water soaked overnight is added, centrifugation takes supernatant i.e.
?.
The preparation method of wormwood bath foam, includes the following steps:
(1) each component is weighed by the above parts by weight, by the tuber of stemona, sweet wormwood, radix saposhnikoviae, gynostemma pentaphylla, Chinese honey locust co-grinding to 60 mesh,
It is spare to obtain traditional Chinese medicine powder, it is spare;
(2) it with after 80-100 DEG C of steam treatment traditional Chinese medicine powder 5min, is cooled to room temperature, adds rose, wild chrysanthemum mixing, after
Continuous steam treatment 1min or so, it is cooling, it is spare;
(3) wormwood stoste is uniformly mixed with smilax extracting solution, step (2) hybrid medicine obtained is added in 30-
After impregnating 4h at 35 DEG C, filtering obtains filtrate and filter residue, spare;
(4) 65% alcohol reflux for taking filter residue that 8 times of weight are added extracts 2 times, each 1.5h, merges ethanol extract,
Ethyl alcohol is recycled, the extracting solution obtained is spare;
(5) filtrate is uniformly mixed with extracting solution, is heated to 40-45 DEG C of insulated and stirred 25min, is again heated to 50-60 DEG C
Insulated and stirred 6min, the bath foam finished product obtained after cooling.
2 bath foam of embodiment
Component: 42 parts of wormwood stostes, 12 portions of Chinese honey locusts, 10 parts of wild chrysanthemums, 6 parts of tubers of stemona, 4 portions of sweet wormwoods, 8 portions of roses, 5 parts it is anti-
Wind, 3 portions of gynostemma pentaphylla, 10 parts of smilax extracting solutions.
The preparation of the smilax extracting solution: after smilax is crushed, 12 times of 80% ethyl alcohol is added and flows back at 70 DEG C
It extracts 2 times, extracts 40min every time, merge 2 times and extract obtained filtrate, ethyl alcohol is recovered under reduced pressure to get smilax extracting solution.
The preparation of the wormwood stoste: after wormwood is smashed to pieces, 10 times of water soaked overnight is added, centrifugation takes supernatant i.e.
?.
The preparation method of wormwood bath foam, includes the following steps:
(1) each component is weighed by the above parts by weight, by the tuber of stemona, sweet wormwood, radix saposhnikoviae, gynostemma pentaphylla, Chinese honey locust co-grinding to 60 mesh,
It is spare to obtain traditional Chinese medicine powder, it is spare;
(2) it with after 80-100 DEG C of steam treatment traditional Chinese medicine powder 5min, is cooled to room temperature, adds rose, wild chrysanthemum mixing, after
Continuous steam treatment 1min or so, it is cooling, it is spare;
(3) wormwood stoste is uniformly mixed with smilax extracting solution, step (2) hybrid medicine obtained is added in 30-
After impregnating 4h at 35 DEG C, filtering obtains filtrate and filter residue, spare;
(4) 70% alcohol reflux for taking filter residue that 10 times of weight are added extracts 3 times, each 1h, merges ethanol extract, returns
Ethyl alcohol is received, the extracting solution obtained is spare;
(5) filtrate is uniformly mixed with extracting solution, is heated to 40-45 DEG C of insulated and stirred 28min, is again heated to 50-60 DEG C
Insulated and stirred 8min, the bath foam finished product obtained after cooling.
3 bath foam of embodiment
Component: 30 parts of wormwood stostes, 12 portions of Chinese honey locusts, 10 parts of wild chrysanthemums, 8 parts of tubers of stemona, 5 portions of sweet wormwoods, 8 portions of roses, 5 parts it is anti-
Wind, 3 portions of gynostemma pentaphylla, 10 parts of smilax extracting solutions.
The preparation of the smilax extracting solution: after smilax is crushed, 12 times of 80% ethyl alcohol is added and flows back at 70 DEG C
It extracts 2 times, extracts 40min every time, merge 2 times and extract obtained filtrate, ethyl alcohol is recovered under reduced pressure to get smilax extracting solution.
The preparation of the wormwood stoste: after wormwood is smashed to pieces, 10 times of water soaked overnight is added, centrifugation takes supernatant i.e.
?.
The preparation method of wormwood bath foam, includes the following steps:
(1) each component is weighed by the above parts by weight, by the tuber of stemona, sweet wormwood, radix saposhnikoviae, gynostemma pentaphylla, Chinese honey locust co-grinding to 80 mesh,
It is spare to obtain traditional Chinese medicine powder, it is spare;
(2) it with after 80-100 DEG C of steam treatment traditional Chinese medicine powder 6min, is cooled to room temperature, adds rose, wild chrysanthemum mixing, after
Continuous steam treatment 1min or so, it is cooling, it is spare;
(3) wormwood stoste is uniformly mixed with smilax extracting solution, step (2) hybrid medicine obtained is added in 30-
After impregnating 4.5h at 35 DEG C, filtering obtains filtrate and filter residue, spare;
(4) 70% alcohol reflux for taking filter residue that 10 times of weight are added extracts 2 times, each 1.5h, merges ethanol extract,
Ethyl alcohol is recycled, the extracting solution obtained is spare;
(5) filtrate is uniformly mixed with extracting solution, is heated to 40-45 DEG C of insulated and stirred 25min, is again heated to 50-60 DEG C
Insulated and stirred 8min, the bath foam finished product obtained after cooling.
4 bath foam of embodiment
Component: 50 parts of wormwood stostes, 15 portions of Chinese honey locusts, 12 parts of wild chrysanthemums, 10 parts of tubers of stemona, 6 portions of sweet wormwoods, 10 portions of roses, 6 parts it is anti-
Wind, 4 portions of gynostemma pentaphylla, 12 parts of smilax extracting solutions.
The preparation of the smilax extracting solution: after smilax is crushed, 12 times of 80% ethyl alcohol is added and flows back at 70 DEG C
It extracts 2 times, extracts 40min every time, merge 2 times and extract obtained filtrate, ethyl alcohol is recovered under reduced pressure to get smilax extracting solution.
The preparation of the wormwood stoste: after wormwood is smashed to pieces, 10 times of water soaked overnight is added, centrifugation takes supernatant i.e.
?.
The preparation method of wormwood bath foam, includes the following steps:
(1) each component is weighed by the above parts by weight, by the tuber of stemona, sweet wormwood, radix saposhnikoviae, gynostemma pentaphylla, Chinese honey locust co-grinding to 80 mesh,
It is spare to obtain traditional Chinese medicine powder, it is spare;
(2) it with after 80-100 DEG C of steam treatment traditional Chinese medicine powder 6min, is cooled to room temperature, adds rose, wild chrysanthemum mixing, after
Continuous steam treatment 1min or so, it is cooling, it is spare;
(3) wormwood stoste is uniformly mixed with smilax extracting solution, step (2) hybrid medicine obtained is added in 30-
After impregnating 5h at 35 DEG C, filtering obtains filtrate and filter residue, spare;
(4) 70% alcohol reflux for taking filter residue that 10 times of weight are added extracts 3 times, each 1h, merges ethanol extract, returns
Ethyl alcohol is received, the extracting solution obtained is spare;
(5) filtrate is uniformly mixed with extracting solution, is heated to 40-45 DEG C of insulated and stirred 30min, is again heated to 50-60 DEG C
Insulated and stirred 8min, the bath foam finished product obtained after cooling.
5 bath oil of embodiment
It takes shower liquid product made of section Example 1 to be heated to 40 DEG C or so, the olive oil emulsification of its quality 3% is added
After agent is uniformly mixed, stop heating, it is cooling, that is, obtain shower milk product.
6 bath oil of embodiment
It takes shower liquid product made of section Example 1 to be heated to 40 DEG C or so, the carragheen stirring of its quality 4% is added
After mixing, stop heating, it is cooling, that is, obtain shower milk product.
1 low dose group of comparative example
Comparative example 1 is the difference from embodiment 1 is that component is different, for 20 parts of wormwood stostes, 8 portions of Chinese honey locusts, 6 parts of wild chrysanthemums, 4
Part tuber of stemona, 2 portions of sweet wormwoods, 4 portions of roses, 2 parts of radix saposhnikoviaes, 1 portion of gynostemma pentaphylla, 6 parts of smilax extracting solutions.;Remaining process is identical.
2 high dose group of comparative example
Comparative example 2 is that component is different from the difference of embodiment 4, is 55 parts of wormwood stostes, 20 portions of Chinese honey locusts, 15 portions of mother chrysanthemums
Flower, 12 parts of tubers of stemona, 8 portions of sweet wormwoods, 12 portions of roses, 8 parts of radix saposhnikoviaes, 65 portions of gynostemma pentaphylla, 14 parts of smilax extracting solutions;Remaining process phase
Together.
Experimental study:
1, Study on Preparation:
1.1 traditional Chinese medicine powder partial sizes research: change 1 preparation process of embodiment in traditional Chinese medicine powder mesh number: 40 mesh, 60 mesh, 80 mesh,
100 mesh, 120 mesh, are made different shower liquid products, after 1 times of dilution of taking a shower made of research institute to concentration be 4.03 ×
104The coli test of cfu/ml is acted on bacteria suspension.As a result, it has been found that bath foam made by 60 mesh, 80 mesh traditional Chinese medicine powders
Inhibiting rate is 68.9%, 71.2% or so, higher than the 51%-63% of other mesh numbers, there is significant difference;And in 40-60 mesh
Bath foam made of medicinal powder, which is stored one week or so, not to be precipitated, and bath foam made of the above Chinese medicine of 100 mesh is stored one week or so
There is slight research of chaotic phenomenon in bottom.
The research of emulsifier used in 1.2 bath oils: research Arabic gum, xanthan gum, carragheen, lecithin, lanolin, olive
Rate and bubble effect are dissolved in stirring of the bath oil made by the naturally occurring emulsifying agents such as olive emulsifier in equal amount water;As a result
It has been shown that, select emulsifier ratio in 3-4%, using olive emulsifier, carragheen as raw material, made bath oil it is molten
It is very fast to change rate, can dissolve and finish in 20s, it is good to dissolve effect, and be able to maintain preferable bubble effect.
2, cavy part itch model antipruritic experimental study: is caused using histamine phosphate.Choose 300~400g of weight health globefish
Mouse 90, half male and half female is randomly divided into 9 groups, and every group 10, blank control group (distilled water), the antipruritic anti-inflammation water group of positive control,
Bath foam liquid/bath oil made by 1-6 of the embodiment of the present invention and comparative example 1-2 is experiment Chinese medicine.Test preceding each group cavy on the 1st
Back shaving, and corresponding experiment tested material 1 time is applied outside groups of animals shaving back, the same day is tested, is abraded and is carried on the back with coarse sandpaper
At portion's shaving, to damage epidermis, skin is slight, and oozing of blood is degree, area 1cm2, part applies again tests tested material 1 time, and last applies real
After testing tested material 10min, start to drip 0.01% phosphoric acid group at the surface of a wound by solution 0.05ml/ only, hereafter, to press every 3min
0.02%, 0.03%, 0.04%......... progressive concentration are 0.05ml/ every time, until later licking the right side to there is cavy
Metapedes stops, and until cavy finally occur and later lick behind the right side, histamine phosphate total amount (ug) to be administered is itch-threshold, record when sufficient
Each group of data, data carry out statistics T inspection, and statistical result is as shown in table 1:
Influence of 1 bath foam of the table/bath oil to cavy itch-threshold caused by histamine phosphate
Group | Itch-threshold (ug) | Increase rate |
Blank control group | 43.2±11.1 | —— |
Positive controls | 79.8±16.7 | 84.7% |
Embodiment 1 | 64.2±12.3 | 48.6% |
Embodiment 2 | 67.6±13.5 | 56.4% |
Embodiment 3 | 66.4±11.6 | 53.7% |
Embodiment 4 | 63.9±10.3 | 47.9% |
Embodiment 5 | 65.7±10.3 | 52.1% |
Embodiment 6 | 63.6±11.6 | 49.5% |
Comparative example 1 | 59.2±9.4 | 37.0% |
Comparative example 2 | 61.4±10.1 | 42.1% |
3, bacteriostatic experiment is studied: being detected Chinese medicine antibacterial maintenance of the present invention according to " disinfection technology standard " (version in 2017) and is taken a shower
Bath foam/bath oil made by the bacteriostasis property of liquid, Example 1-6 and comparative example 1-2 is respectively acting on after 1 times of dilution
Concentration is 4.21 × 104The coli test bacteria suspension of cfu/ml, the golden yellow grape that concentration is 2.13 × 104cfu/ml
Coccus test bacteria suspension, concentration are 2.78 × 104Cfu/ml shigella dysenteriae, concentration are 1.67 × 104Cfu/ml Epidermophvton tinea
Bacterium 2min, statistics calculate its each time average inhibition to pathogenic skin bacterium/fungi, as shown in table 2:
2 bath foams of table/bath oil bacteriostasis
It is important to point out that, above embodiments and test example are only limitted to do further technical solution of the present invention herein
Elaboration and understanding, should not be understood as it is further to technical solution of the present invention limited, what those skilled in the art made
The innovation and creation of non-protruding essential characteristics and marked improvement still fall within protection category of the invention.
Claims (9)
1. a kind of wormwood bath foam, which is characterized in that the component including following parts by weight: 24-50 parts of wormwood stostes, 10-15 parts
Chinese honey locust, 8-12 part wild chrysanthemum, the 6-10 parts of tubers of stemona, 4-6 portions of sweet wormwoods, 6-10 portions of roses, 4-6 parts of radix saposhnikoviaes, 2-4 parts of gynostemma pentaphylla, 8-12
Part smilax extracting solution.
2. wormwood bath foam as described in claim 1, which is characterized in that the component including following parts by weight: 42 parts of wormwood originals
Liquid, 12 portions of Chinese honey locusts, 10 parts of wild chrysanthemums, 6 parts of tubers of stemona, 4 portions of sweet wormwoods, 8 portions of roses, 5 parts of radix saposhnikoviaes, 3 portions of gynostemma pentaphylla, 10 portions of smilaxs mention
Take liquid.
3. wormwood bath foam as claimed in claim 1 or 2, which is characterized in that the preparation of the smilax extracting solution: by native Fu
After Siberian cocklebur crushes, 12 times of 80% ethyl alcohol refluxing extraction 2 times at 70 DEG C are added, extracts 40min every time, merges 2 extractions and obtained
Filtrate is obtained, ethyl alcohol is recovered under reduced pressure to get smilax extracting solution.
4. wormwood bath foam as claimed in claim 1 or 2, which is characterized in that the preparation of the wormwood stoste: wormwood is smashed to pieces
Afterwards, 10 times of water soaked overnight is added, centrifugation takes supernatant to obtain the final product.
5. the preparation method of wormwood bath foam as claimed in claim 1 or 2, which comprises the steps of:
(1) each component is weighed by the above parts by weight, by the tuber of stemona, sweet wormwood, radix saposhnikoviae, gynostemma pentaphylla, Chinese honey locust co-grinding, obtains traditional Chinese medicine powder
It is spare, it is spare;
(2) it with after steam treatment traditional Chinese medicine powder 5-6min, is cooled to room temperature, adds rose, wild chrysanthemum mixing, continue at steam
1min or so is managed, it is cooling, it is spare;
(3) wormwood stoste is uniformly mixed with smilax extracting solution, step (2) hybrid medicine obtained is added at 30-35 DEG C
After lower immersion 4-5h, filtering obtains filtrate and filter residue, spare;
(4) alcohol reflux for taking filter residue that 8-10 times of weight is added extracts 2-3 times, each 1-1.5h, merges ethanol extract, recycling
Ethyl alcohol, the extracting solution obtained are spare;
(5) filtrate is uniformly mixed with extracting solution, is heated to 40-45 DEG C of insulated and stirred 25-30min, be again heated to 50-60 DEG C of guarantor
Temperature stirring 6-8min, the bath foam finished product obtained after cooling.
6. the preparation method of wormwood bath foam as claimed in claim 5, which is characterized in that the traditional Chinese medicine powder is 60-80 mesh.
7. the preparation method of wormwood bath foam as claimed in claim 5, which is characterized in that the temperature of the steam is 80-100
℃。
8. the preparation method of wormwood bath foam as claimed in claim 5, which is characterized in that the step (4), concentration of alcohol are
65-70%.
9. the preparation method of wormwood bath foam as claimed in claim 5, which is characterized in that the wormwood bath foam finished product adds
The olive emulsifier or carragheen for entering its quality 3%-4%, can be made into wormwood bath oil.
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