CN107136052B - Medical speed-regulating and temperature-reducing device - Google Patents
Medical speed-regulating and temperature-reducing device Download PDFInfo
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- CN107136052B CN107136052B CN201710530085.8A CN201710530085A CN107136052B CN 107136052 B CN107136052 B CN 107136052B CN 201710530085 A CN201710530085 A CN 201710530085A CN 107136052 B CN107136052 B CN 107136052B
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
- A01N1/0252—Temperature controlling refrigerating apparatus, i.e. devices used to actively control the temperature of a designated internal volume, e.g. refrigerators, freeze-drying apparatus or liquid nitrogen baths
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D3/00—Devices using other cold materials; Devices using cold-storage bodies
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Abstract
The invention discloses a novel medical speed-regulating and temperature-reducing device with a communication function, which comprises: the upper shell is internally provided with a first shell sealing cavity, a first freezing cavity, a first specially-made energy storage material cavity and a second specially-made energy storage material cavity; the lower shell is connected with the upper shell through a metal rod, a plurality of second freezing tube cavities, a second shell sealing cavity and a third specially-made energy storage material cavity are arranged in the lower shell, the second freezing tube cavities are used for placing freezing tubes, and phase change materials are also placed in the second freezing tube cavities; the temperature adjusting device comprises four specially-made energy storage rods; the temperature and humidity probe is arranged on the outer side of one of the second freezing tube cavities and used for acquiring temperature information and humidity information; the temperature and humidity display panel is arranged on the front surface of the upper shell and used for displaying humidity information and temperature information; the special energy storage material comprises a first special energy storage material, a second special energy storage material and a third special energy storage material and is used for changing the cooling rate.
Description
Technical Field
The invention belongs to the field of low-temperature freezing and heat exchange, and particularly relates to a medical speed-regulating and temperature-reducing device.
Background
Along with the continuous growth of national economy of China, the requirement of people on health is higher and higher, scientific research is needed to deal with emerging diseases for the emerging diseases, the research on cells is particularly critical, and how to freeze the cells is beneficial to long-term scientific research application, so that the method becomes a topic which is increasingly concerned by people, particularly scientific researchers.
The cell freezing is to store the cells in a low-temperature environment, reduce cell metabolism, ensure that various biological characteristics of the stored cells are basically complete, facilitate long-term storage and be beneficial to long-term scientific research and application. The optimal freezing rates corresponding to different cells and tissues are different, the traditional program cooling device can only reduce the sample speed at a fixed cooling rate, the cooling rate cannot be adjusted, and the long-term preservation of the tissues and organs cannot be effectively realized.
Disclosure of Invention
The present invention has been made to solve the above problems, and an object of the present invention is to provide a medical speed-adjusting and temperature-reducing device having a communication function and capable of conveniently adjusting a temperature-reducing rate.
The invention provides a medical speed-regulating and temperature-reducing device, which is characterized by comprising: the upper shell is internally provided with a first shell sealing cavity, a first freezing cavity, a first specially-made energy storage material cavity and a second specially-made energy storage material cavity; the lower shell is connected with the upper shell through a metal rod, a plurality of second freezing tube cavities, a second shell sealing cavity and a third specially-made energy storage material cavity are arranged in the lower shell, the second freezing tube cavities are used for placing freezing tubes, and phase change materials are also placed in the second freezing tube cavities; the temperature adjusting device comprises four specially-made energy storage rods; the temperature and humidity probe is arranged on the outer side of one of the second freezing tube cavities and used for acquiring temperature information and humidity information; the temperature and humidity display panel is arranged on the front surface of the upper shell and used for displaying humidity information and temperature information; the special energy storage material comprises a first special energy storage material arranged in a first special energy storage material cavity, a second special energy storage material arranged in a second special energy storage material cavity and a third special energy storage material arranged in a third special energy storage material cavity, and is used for changing the cooling rate, wherein four energy storage rod cavities which are communicated with each other are further arranged in the lower shell, and the four special energy storage rods are respectively and movably arranged in the corresponding energy storage rod cavities, so that a user can change the cooling rate by inserting or extracting the special energy storage rods.
The medical speed-regulating cooling device provided by the invention can also comprise: and the outer shell is used for sleeving the outer parts of the upper shell and the lower shell under the condition that the temperature reduction rate is required to be slower, so that the temperature reduction rate is reduced.
The medical speed-regulating and temperature-reducing device provided by the invention can also have the following characteristics: wherein, the second freezing lumen is evenly distributed according to the circumference.
The medical speed-regulating and temperature-reducing device provided by the invention can also have the following characteristics: the number of the metal rods is four, and the metal rods sequentially penetrate through a first fixing hole formed in the upper shell and a second fixing hole formed in the lower shell so as to connect the upper shell and the lower shell.
The medical speed-regulating and temperature-reducing device provided by the invention can also have the following characteristics: wherein, special heat preservation materials, special energy storage materials or phase change materials are arranged in the four energy storage rod accommodating cavities.
The medical speed-regulating and temperature-reducing device provided by the invention can also have the following characteristics: wherein the specially-made energy storage material is a composite material with the heat conductivity coefficient of 15W/(+) -25W/(+) -K.
The medical speed-regulating and temperature-reducing device provided by the invention can also have the following characteristics: wherein the phase-change material has a phase-change temperature of 13-7 deg.C.
Action and Effect of the invention
According to the medical speed-regulating cooling device, the phase-change material filled in the cryopreservation tube cavity is adopted, so that the vitrification state in the cell cooling process can be increased, and the survival probability of rewarming cells and the integrity of histiocytes can be enhanced. Because the four specially-made energy storage rods movably arranged in the energy storage rod cavity are adopted, the user can change the cooling rate by inserting or extracting the specially-made energy storage rods, and the change operation of the cooling rate is simpler and more convenient.
Drawings
FIG. 1 is a schematic structural diagram of an embodiment of the present invention;
FIG. 2 is an external structural view of an embodiment of the present invention;
fig. 3 is an external configuration diagram of the embodiment of the present invention.
Detailed Description
In order to make the technical means and functions of the present invention easy to understand, the present invention is specifically described below with reference to the embodiments and the accompanying drawings.
Example (b):
fig. 1 is a schematic structural diagram of an embodiment of the present invention, fig. 2 is a schematic external structural diagram of the embodiment of the present invention, and fig. 3 is a schematic external structural diagram of the embodiment of the present invention.
As shown in fig. 1, fig. 2 and fig. 3, a medical speed-regulating and temperature-reducing device 100 of the present embodiment includes: the temperature and humidity measuring device comprises an upper shell 1, a lower shell 6, a temperature adjusting device (not shown in the figure), a temperature and humidity probe 11, a temperature and humidity display panel 12, a special energy storage material (not shown in the figure) and an outer shell (not shown in the figure).
The upper shell 1 is internally provided with a first shell sealing cavity 2, a first freezing cavity 3, a first specially-made energy storage material cavity 4 and a second specially-made energy storage material cavity 5.
The lower shell 6 is connected with the upper shell 1 through four metal rods (not shown in the figure), and a plurality of second freezing and storing cavities 7, a second shell sealing cavity 8, a third special energy storing material cavity 9 and four energy storing rod cavities (not shown in the figure) which are communicated with each other are arranged in the lower shell.
The metal rod passes through a first fixing hole 13 provided on the upper case 1 and a second fixing hole 14 provided on the lower case 6 in this order to connect the upper case 1 and the lower case 6.
The second freezing tube cavities 7 are evenly distributed according to the circumference and used for placing the freezing tubes 10, and phase-change materials are also placed in the second freezing tube cavities 7.
Special heat insulating materials, special energy storage materials or phase change materials are arranged in the cavities of the four energy storage rods.
The special heat-insulating material is formed by compounding the material A and the material B according to a certain proportion, and has the characteristics of low heat conductivity coefficient, low water absorption, high density, no toxicity, no flammability and environmental protection.
The special energy storage material is a composite material with the heat conductivity coefficient of 15W/square meter K-25W/square meter K.
The phase-change material is a phase-change material with the phase-change temperature of 13-7 ℃ below zero.
The temperature adjusting device comprises four specially-made energy storage rods, and the four specially-made energy storage rods are movably arranged in corresponding energy storage rod cavities respectively, so that a user can change the cooling rate by inserting or extracting the specially-made energy storage rods.
Temperature and humidity probe 11, set up in the outside of one of them of second cryopreserved lumen 7, gather temperature information through temperature probe, humidity probe gathers humidity information.
And a temperature and humidity display panel 12 provided on the front surface of the upper case 1 and configured to display humidity information and temperature information.
The temperature and humidity probe 11 is connected with the temperature and humidity display panel 12 through a temperature and humidity probe connecting line.
The purpose-built energy storage material comprises a first purpose-built energy storage material arranged in a first purpose-built energy storage material cavity 4, a second purpose-built energy storage material arranged in a second purpose-built energy storage material cavity 5 and a third purpose-built energy storage material arranged in a third purpose-built energy storage material cavity 9, and is used for changing the cooling rate.
And the outer shell is used for sleeving the outer parts of the upper shell 1 and the lower shell 6 under the condition that the temperature reduction rate is required to be slower, so that the temperature reduction rate is reduced.
The working process of the embodiment:
referring to fig. 1, 2 and 3, taking a pig cartilage tissue slice as an example, a bean-sized cartilage tissue is taken from a pig bone, and the pig cartilage tissue is placed in a freezing tube 10 and poured with a DMSO solution prepared in advance through a certain pretreatment work of a biological agent.
Respectively placing the freezing tube 10 into the first freezing tube cavity 3 and the second freezing tube cavity 7, enabling the freezing tube 10 to be immersed into a phase-change material, then selecting an outer shell with different wall thicknesses (the wall thickness of the outer shell is not less than 5mm) according to the required cooling rate, or extracting or inserting a first specially-made energy storage rod 15, a second specially-made energy storage rod 16, a third specially-made energy storage rod 17 and a fourth specially-made energy storage rod from the energy storage rod cavity to achieve the required cooling rate, connecting the upper shell 1 and the lower shell 6 together, enabling the first shell sealing cavity 2 and the second shell sealing cavity 8 to be attached together, then placing the whole device in a refrigerator at-80 ℃, and displaying the temperature and humidity on a control panel. An operator can further adjust and optimize the cooling rate according to the data, and can start the small fan fixed at the port of the first specially-made energy storage rod 15 through a bolt to adjust the cooling rate, so that convection and radiant heat exchange is enhanced, and the cooling rate is accelerated.
Effects and effects of the embodiments
Because the phase-change material filled in the cryopreservation tube cavity is adopted, the vitrification state of the cells in the cooling process can be increased, and the survival probability of rewarming cells and the integrity of histiocytes can be enhanced. Because the four specially-made energy storage rods movably arranged in the energy storage rod cavity are adopted, the user can change the cooling rate by inserting or extracting the specially-made energy storage rods, and the change operation of the cooling rate is simpler and more convenient. The cooling rate can also be varied by selecting outer shells of different wall thickness.
The above embodiments are preferred examples of the present invention, and are not intended to limit the scope of the present invention.
Claims (7)
1. A medical speed-regulating cooling device is characterized by comprising:
the upper shell is internally provided with a first shell sealing cavity, a first freezing cavity, a first energy storage material cavity and a second energy storage material cavity;
the lower shell is connected with the upper shell through a metal rod, a plurality of second freezing tube cavities, a second shell sealing cavity and a third energy storage material cavity are arranged in the lower shell, the second freezing tube cavities are used for placing freezing tubes, and phase change materials are also placed in the second freezing tube cavities;
the temperature adjusting device comprises four energy storage rods;
the temperature and humidity probe is arranged on the outer side of one of the second freezing tube cavities and used for acquiring temperature information and humidity information;
the temperature and humidity display panel is arranged on the front surface of the upper shell and used for displaying humidity information and the temperature information;
the energy storage material comprises a first energy storage material arranged in the first energy storage material cavity, a second energy storage material arranged in the second energy storage material cavity and a third energy storage material arranged in the third energy storage material cavity and is used for changing the cooling rate,
wherein, still be provided with four energy storage pole chambeies of intercommunication each other in the inferior valve body, four energy storage poles movably set up respectively in the energy storage pole intracavity that corresponds for the user can change cooling rate through inserting or taking out the energy storage pole.
2. A medical speed-regulating temperature-reducing device according to claim 1, further comprising:
and the outer shell is sleeved outside the upper shell and the lower shell under the condition that the cooling rate is required to be slower, so that the cooling rate is reduced.
3. A medical speed-regulating temperature-reducing device according to claim 1, characterized in that:
wherein, the second cryopreserving pipe cavity is evenly distributed according to the circumference.
4. A medical speed-regulating temperature-reducing device according to claim 1, characterized in that:
the number of the metal rods is four, and the metal rods sequentially penetrate through a first fixing hole formed in the upper shell and a second fixing hole formed in the lower shell so as to connect the upper shell and the lower shell.
5. A medical speed-regulating temperature-reducing device according to claim 1, characterized in that:
and heat insulation materials, energy storage materials or phase change materials are arranged in the four energy storage rod accommodating cavities.
6. A medical speed-regulating temperature-reducing device according to claim 5, wherein:
the energy storage material is a composite material with the heat conductivity coefficient of 15W/(+) -K-square meter to 25W/(+) -K.
7. A medical speed-regulating temperature-reducing device according to claim 5, wherein:
wherein the phase-change material has a phase-change temperature of 13-7 deg.C.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710530085.8A CN107136052B (en) | 2017-07-03 | 2017-07-03 | Medical speed-regulating and temperature-reducing device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710530085.8A CN107136052B (en) | 2017-07-03 | 2017-07-03 | Medical speed-regulating and temperature-reducing device |
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| Publication Number | Publication Date |
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| CN107136052A CN107136052A (en) | 2017-09-08 |
| CN107136052B true CN107136052B (en) | 2020-11-03 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710530085.8A Active CN107136052B (en) | 2017-07-03 | 2017-07-03 | Medical speed-regulating and temperature-reducing device |
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| CN112167242B (en) * | 2020-09-24 | 2022-03-25 | 清华大学 | No active cooling low temperature storage and transportation device based on multilayer phase change material |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201752216U (en) * | 2010-06-04 | 2011-03-02 | 北京慧荣和科技有限公司 | Program temperature reduction box |
| WO2013002324A1 (en) * | 2011-06-28 | 2013-01-03 | 株式会社スギヤマゲン | Temperature-management system |
| CN103988835A (en) * | 2014-03-12 | 2014-08-20 | 杭州科默斯科技有限公司 | Cell freezing box |
| CN203916695U (en) * | 2014-06-25 | 2014-11-05 | 杭州科默斯科技有限公司 | A kind of novel test tube program temperature reduction box |
| CN205418535U (en) * | 2016-03-30 | 2016-08-03 | 杭州元研细胞生物科技有限公司 | Program temperature reduction box |
| CN106386786A (en) * | 2016-11-30 | 2017-02-15 | 南京瘦懒猴信息科技有限公司 | Freezing preservation container for low-temperature-sensitive biological sample |
-
2017
- 2017-07-03 CN CN201710530085.8A patent/CN107136052B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201752216U (en) * | 2010-06-04 | 2011-03-02 | 北京慧荣和科技有限公司 | Program temperature reduction box |
| WO2013002324A1 (en) * | 2011-06-28 | 2013-01-03 | 株式会社スギヤマゲン | Temperature-management system |
| CN103988835A (en) * | 2014-03-12 | 2014-08-20 | 杭州科默斯科技有限公司 | Cell freezing box |
| CN203916695U (en) * | 2014-06-25 | 2014-11-05 | 杭州科默斯科技有限公司 | A kind of novel test tube program temperature reduction box |
| CN205418535U (en) * | 2016-03-30 | 2016-08-03 | 杭州元研细胞生物科技有限公司 | Program temperature reduction box |
| CN106386786A (en) * | 2016-11-30 | 2017-02-15 | 南京瘦懒猴信息科技有限公司 | Freezing preservation container for low-temperature-sensitive biological sample |
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| CN107136052A (en) | 2017-09-08 |
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