CN105191910B - A kind of portable ultralow temperature cell transport storage device - Google Patents
A kind of portable ultralow temperature cell transport storage device Download PDFInfo
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- CN105191910B CN105191910B CN201510694875.0A CN201510694875A CN105191910B CN 105191910 B CN105191910 B CN 105191910B CN 201510694875 A CN201510694875 A CN 201510694875A CN 105191910 B CN105191910 B CN 105191910B
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- cell
- liquid nitrogen
- storage device
- transport storage
- ultralow temperature
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Abstract
The invention discloses a kind of portable ultralow temperature cell transport storage device, including a shell, liquid nitrogen storage box is provided with the shell, the liquid nitrogen storage box includes outer layer incubator and internal layer incubator, an external hollow chamber is formed between the outer layer incubator and the shell, an inner hollow chamber is formed between the outer layer incubator and internal layer incubator；The external hollow intracavitary is filled with insulation filling materials, and the inner hollow intracavitary is filled with liquid nitrogen adsorbent, groove is provided with the internal layer incubator, and a frozen cell box or single cell cryopreservation tube only are placed with the groove.The present invention realizes the storage and transfer of frozen cell by liquid nitrogen in internal layer incubator formation ultra-low temperature surroundings, significantly improve the quality of freeze-stored cell, avoid damage of the frozen cell in transport process caused by temperature acute variation to cell, portable design is convenient and practical.Equipment economy, there is larger business promotion prospect.
Description
Technical field
The present invention relates to cell memory transfer technical field, more particularly to a kind of portable ultralow temperature cell transport storage dress
Put.
Background technology
The major experimental object of RESEARCH ON CELL-BIOLOGY is the cell or cell line of various original cuitures or Secondary Culture.For
Avoid cultivating cell pollute caused by long-term in vitro incubation or gene mutation caused by repeatedly passing on, experimenter's meeting
The cell cultivated is frozen when growing animated period, freeze-stored cell is stored in the cell cryopreservation tube for adding cells frozen storing liquid
In, it is then placed into -196 DEG C of liquid nitrogen, under this ultra-low temperature surroundings, cell can preserve for a long time.When experiment needs,
Institute's freeze-stored cell can be carried out required experiment by experimenter in 37 DEG C of recoveries, can so ensure cell to greatest extent
Genetic stability.
RESEARCH ON CELL-BIOLOGY shows that freeze-stored cell storage temperature is preferably controlled below -130 DEG C all the time, in freeze-stored cell
Water will not form crystallization, eucaryotic cell structure will not be destroyed, so as to greatest extent ensure freeze-stored cell quality, after making recovery
Cell viability it is higher.In addition, research shows that intracellular metabolism can almost stop completely when temperature is reduced to -130 DEG C
Only, the configuration state of cell interior high-sequential will not be disturbed, and cell internal protein matter, enzyme and other organelles will not be by
Destroy.Not only there is normal cellular morphology after freeze-stored cell recovery, it is often more important that the complete bio for maintaining cell is special
Sign.Therefore must assure that all the time in less than -130 DEG C of ultra-low temperature surroundings, only in the access to freezing cell under state
The freeze-stored cell so stored just can guarantee that required quality when scientific research in future or treatment are fed back.
Transport storage device without special frozen cell on the market at present.Therefore under current operating condition, extraction,
When cell bank arrangement is either carried out using freeze-stored cell or when frozen cell is transported, typically cell cryopreservation tube is placed in
Dry ice is either in common ice cube to maintain low temperature or using program temperature reduction box, but such temperature conditionss can make freeze-stored cell
Unnecessary heating is undergone, i.e., is taken from -196 DEG C of low temperature environments in more than -20 DEG C of environment, then by such environment temperature
Return in -196 DEG C of liquid nitrogen.So violent temperature change can make frozen cell activity and quality bring serious influence.I.e.
Make open-assembly time very short, frozen cell still experienced once violent temperature change, as long as frozen cell temperature is from -196 DEG C
Slowly lasting change can be occurred, send out by being increased to close to vitrified temperature, i.e., more than -130 DEG C, cell cryopreservation liquor inside
Raw recrystallization.For most cells at -5 DEG C~-60 DEG C, intracellular forms ice crystal, causes cell death, and therefore -5 DEG C~-60
DEG C be referred to as cell dangerous temperature area.
Some operating personnel carry out aforesaid operations using the thermos cup equipped with liquid nitrogen, although ensure that low temperature environment,
It is the transport under the unsuitable long range of such measure or jounce condition, and when taking cryopreservation tube with tweezers, easily occurs
Frostbite.Additionally due to cryopreservation tube is directly to throw into liquid nitrogen, lost if there is information on cryopreservation tube in access, will appear from freezing
Pipe inner cell is deposited to obscure.
The storage cell device of Publication No. CN103988836A patent " a kind of cell the storage box ", for different thin
Born of the same parents need to be stored in required temperature environment after recovery carries out preservation transport, and meeting cell freezing box can not reach
Requirement, but this be only limitted to recovery after preservation transport, if cell do not recover also, it is necessary in a cold or frozen state short distance turn
Move, the invention does not reach requirement.
The content of the invention
The technical problem to be solved in the present invention is due to not having when frozen cell is shifted in the prior art in order to overcome
There is special transfer storage device and cause to destroy frozen cell activity, easily cause frostbite and easily cryopreservation tube information occur
The defects of losing and causing cryopreservation tube inner cell to be obscured, it is proposed that one kind can be used for frozen cell short distance memory transfer and conveniently
The storage device for the frozen cell taken.
The present invention solves above-mentioned technical problem by following technical proposals：
A kind of portable ultralow temperature cell transport storage device, its feature is, including a shell, is provided with the shell
Liquid nitrogen storage box, the liquid nitrogen storage box include outer layer incubator and internal layer incubator, the outer layer incubator and the shell
Between form an external hollow chamber, form an inner hollow chamber between the outer layer incubator and internal layer incubator；
The external hollow intracavitary is filled with insulation filling materials, and the inner hollow intracavitary is filled with liquid nitrogen adsorbent, institute
State in internal layer incubator and be provided with a groove, a frozen cell box is placed with the groove.
In this programme, frozen cell box is in liquid nitrogen environment by the adsorbent liquid nitrogen of liquid nitrogen, ensure that
Frozen cell is in ultra-low temperature surroundings.In addition, insulation filling materials are filled with the hollow chamber of outer layer, by isolating inside and outside temperature
It is incubated, extends the time that frozen cell is in ultra-low temperature surroundings, ensure that frozen cell is thin in transfer process
Cytoactive.
It is preferred that each face of the groove is for aluminium sheet or with porous stainless steel web plate.
In this programme, each face of groove is with porous stainless steel web plate, is advantageous to the hot right of internal layer incubation chamber
Stream, ensure that cell is in ultra-low temperature surroundings；And aluminium sheet ensure that cell is in ultra-low temperature surroundings because heat conductivility is good,
And the direct liquid nitrogen that contacts is prevented to cause the situation of frost bitten.
It is preferred that provided with some pipe supports for being used to place frozen cell test tube in the frozen cell box.
It is preferred that the outer wall of the frozen cell box fits in the inwall of the groove.
In this programme, the outer wall of frozen cell box is bonded with the inwall of groove, and nitrogen is let out after reducing liquid nitrogen volatilization
Leakage.
It is preferred that the portable ultralow temperature cell transport storage device is additionally provided with closure, the closure is used for close
Seal the groove.
In this programme, groove is sealed by the closure, can effectively prevent the vibration in transfer process
And impact, and the volatilization of liquid nitrogen is reduced, whole frozen cell box is in uniform ultra-low temperature surroundings.
It is preferred that the upper surface that the external hollow chamber is covered in the liquid nitrogen storage box is used to place freezing provided with some
The tube seat of cell test tube.
In this programme, the tube seat can be used for placing frozen cell test tube, be easy to frozen cell in frozen cell box to try
Pipe picking and placeing and arranging, and avoids obscuring for each frozen cell test tube in fetching process.
It is preferred that the bottom portion of groove is provided with elastic parts, the elastic parts be used for when being pressurized nature with
Switched between compressive state.
In this programme, change the state of elastic parts by pressing frozen cell box, be easy to picking and placeing for frozen cell box,
Improve Consumer's Experience.
It is preferred that being additionally provided with control cabinet in the shell, the control cabinet is integrated in one with the liquid nitrogen storage box.
It is preferred that alarm module, display module, control module, RAM (Random Access are additionally provided with the control cabinet
Memory, random access memory) module and USB (Universal Serial Bus, USB) interface, the alarm mould
Block, the display module, the RAM module and the USB interface electrically connect with the control module.
It is preferred that temperature sensor and liquid level sensor are additionally provided with the groove, the temperature sensor, the liquid level
Sensor electrically connects with the control module.
In this programme, temperature sensor is used for monitoring temperature, and liquid level sensor is used to monitor liquid level, if the temperature monitored
Degree and liquid level have exceeded preset range, then can alarm.
It is preferred that a liquid nitrogen input interface and a liquid nitrogen input pipe are additionally provided with the control cabinet, the liquid nitrogen input
Interface is connected by the liquid nitrogen input pipe and the inner hollow chamber.
It is preferred that the shell is stainless steel casing, the insulation filling materials are heat-preservation cotton filler.
The portable ultralow temperature cell transport storage device also includes a handle, and the both ends of the handle are individually fixed in
The two sides of the liquid nitrogen storage box.
In this programme, the handle can be convenient for carrying the device, improve Consumer's Experience.
It is preferred that the temperature residing for the frozen cell box is -195.8 DEG C~-130 DEG C.
The positive effect of the present invention is：Storage device is transported by the portable ultralow temperature cell of the present invention, can
So that the memory transfer of certain distance is carried out to frozen cell in the case where ensureing frozen cell activity, while can be with monitoring temperature
And liquid level information, it if the temperature and liquid level that monitor exceed preset range, can alarm, remind user to take correlation to arrange in time
Apply.
Brief description of the drawings
Fig. 1 is that the portable ultralow temperature cell of the embodiment of the present invention 1 transports the structural representation of storage device.
Fig. 2 is that the portable ultralow temperature cell of the embodiment of the present invention 1 transports the planar structure schematic diagram that storage device is overlooked.
Fig. 3 is that the portable ultralow temperature cell of the embodiment of the present invention 1 transports the electrical connection schematic diagram in storage device.
Fig. 4 is that the portable ultralow temperature cell of the embodiment of the present invention 2 transports the structural representation of storage device.
Fig. 5 is that the portable ultralow temperature cell of the embodiment of the present invention 2 transports the planar structure schematic diagram that storage device is overlooked.
Fig. 6 is to transport storage device and the access of Traditional Transportation box using the portable ultralow temperature cell of the embodiment of the present invention 2
The motility rate of recovery cell compares figure after frozen cell 30 times.
Fig. 7 is to transport storage device and the access of Traditional Transportation box using the portable ultralow temperature cell of the embodiment of the present invention 2
72 hours multiplication factors of recovery cell compare figure after frozen cell 30 times.
Embodiment
The present invention is further illustrated below by the mode of embodiment, but does not therefore limit the present invention to described reality
Apply among a scope.
Embodiment 1
As shown in figure 1, a kind of portable ultralow temperature cell transport storage device, including a shell 0 and closure 4, this is outer
Liquid nitrogen storage box and control cabinet 3 are provided with shell, the liquid nitrogen storage box and control cabinet 3 are integrated in one, and the shell is heat conductivility
Preferable material, the material can be stainless steel.
The liquid nitrogen storage box includes outer layer incubator 1 and internal layer incubator 2, and one is formed between outer layer incubator 1 and shell 0
External hollow chamber 10, an inner hollow chamber 12 is formed between outer layer incubator 1 and internal layer incubator 2.The portable ultralow temperature is thin
It is as shown in Figure 2 that born of the same parents transport the planar structure schematic diagram that storage device is overlooked.
Heat-preservation cotton filler is filled with external hollow chamber 10, the heat-preservation cotton filler can be by isolating inside and outside temperature
Heat insulation function is realized in the exchange of degree.
Liquid nitrogen adsorbent is filled with inner hollow chamber 12, the liquid nitrogen adsorbent is used to adsorb liquid nitrogen, interior so as to ensure that
The ultra-low temperature surroundings of layer incubator 2, the ultra-low temperature surroundings refer to the environment that the temperature residing for frozen cell box is less than -130 DEG C,
For example the temperature at frozen cell box can be -195.8 DEG C~-130 DEG C.
A groove 21 is additionally provided with the internal layer incubator 2, a frozen cell box 210, the freezing are placed with the groove 21
Some pipe supports 2101 are provided with cell box 210, the pipe support 2101 is used to place frozen cell test tube.It is thin even in access freezing
During born of the same parents' test tube, information is accidentally lost on frozen cell test tube, as long as putting frozen cell test tube in order, will also realize that corresponding cold
Freeze cell test tube relevant information.By the adsorbent liquid nitrogen of liquid nitrogen ensure that frozen cell test tube be in -130 DEG C with
Under.
The boxboard of the internal layer incubator 2 is that groove 21 is all around the stainless (steel) wire with multiple apertures with bottom surface
Plate, so as to be advantageous to the thermal convection current of internal layer incubator 2, it ensure that frozen cell is in ultra-low temperature surroundings.The groove 21 it is front and rear
Left and right is alternatively aluminium sheet, and the aluminium sheet is the aluminium sheet without through hole, because aluminium sheet heat conductivility is good, it is ensured that frozen cell is in
Ultra-low temperature surroundings.The material in each face of groove is not limited to described above, can be selected according to actual conditions, not another here
One repeats.
The outer wall of frozen cell box 210 fits in the inwall of groove 21, reduces the leakage of nitrogen after liquid nitrogen volatilization.
Storage device is transported in transfer process in the portable ultralow temperature cell equipped with frozen cell, and this is portable ultralow
The closure 4 of warm cell transport storage device can effective sealed groove 21, frozen cell box 210 is kept fixation, so as to have
Effect, which avoids the vibration of the frozen cell box 210 in transfer process and impact, may cause the risk of frozen cell tube breaking,
And the leakage of nitrogen after liquid nitrogen volatilization is further reduced, whole frozen cell box 210 is in uniform ultra-low temperature surroundings.
Therefore, in frozen cell to be stored in the liquid nitrogen storage case, it can conveniently realize memory transfer and not destroy
The activity of frozen cell, it is convenient and practical.
In addition, being additionally provided with a liquid nitrogen input pipe 31 and a liquid nitrogen input interface 32 on the control cabinet 3, liquid nitrogen input connects
Mouth 32 is connected by liquid nitrogen input pipe 31 and inner hollow chamber 12, and the liquid nitrogen input pipe 31 is used to liquid nitrogen being input to inside
In middle cavity 12.The liquid nitrogen input interface 32 passes through the fixation that is spirally connected, the liquid nitrogen input interface 32 and liquid nitrogen input pipe with shell 0
31 are fixed by glued seals.Liquid nitrogen can be inputted in real time by the liquid nitrogen input interface 32 and liquid nitrogen input pipe 31, it is convenient
Practicality, drastically increase Consumer's Experience.
As shown in figure 3, the control cabinet 3 is additionally provided with alarm module 303, control module 304, display module 305, RAM module
306 and USB interface 307, liquid level sensor 301 and temperature sensor 302 are additionally provided with groove 21, wherein, liquid level sensor
301st, temperature sensor 302, alarm module 303, display module 305, RAM module 306 and USB interface 307 be and control module
304 electrical connections.
Frozen cell box 210 is taken out to the internal layer for being placed in the portable ultralow temperature cell transport storage device from liquid nitrogen container
When in incubator 2, temperature sensor 302 and liquid level sensor 301 detect internal insulation case 2 temperature and liquid level whether beyond
Default scope, if beyond default scope, control module 304 controls alarm module 303 to be alarmed.And temperature passes
The temperature detected and liquid level information are sent to display mould by sensor 302 and liquid level sensor 301 by control module 304 in real time
Block 305 is shown, and is stored in inside RAM module 306, be ensure that the original, true, accurate, safe of data and can be chased after
Trace back.
In addition, user can obtain conventional temperature and liquid level in frozen cell transfer device in real time by USB interface 307
Information carries out data analysis and cause of accident tracking.
Embodiment 2
As shown in Figure 4 and Figure 5, embodiment 2 has done further improvement on the basis of embodiment 1, thes improvement is that：
The bottom of groove 2 is provided with elastic parts 7, and the elastic parts 7 is used to be cut between nature and compressive state when being pressurized
Change；The end face being bonded in liquid nitrogen storage box with closure 4 is provided with some tube seats 6；And portable ultralow temperature cell transport storage
Device also includes a handle 5, and the both ends of the handle are individually fixed in the two sides of liquid nitrogen storage box.
In this programme, elastic parts 7 that the bottom of groove 2 is set when pressed can nature and compressive state it
Between switch over, when frozen cell box 21 is in groove 2, when elastic parts 7 in the raw when, user press freezing
Cell box 21, due to the interaction of power, the elastic parts 7 is pressurized, and when pressure reaches threshold value, elastic parts 7 is by natural shape
State is switched to compressive state, and now, frozen cell box 21 is completely into groove 2；When user wants to take out the frozen cell box 21
When, the frozen cell box 21 is pressed again, when pressure reaches threshold value, elastic parts 7 switches to nature by compressive state,
Due to the interaction of power, frozen cell box 21 is upspring, and user can conveniently take, and is avoided contact liquid nitrogen environment and led
The situation of frostbite is caused, greatly improves Consumer's Experience.The nature refers to that the elastic parts 7 is the state that nature is bent and stretched,
Compressive state refers to that the elastic parts 7 receives the state of pressure after-contraction.The elastic parts can be spring.
In addition, it is used to place frozen cell provided with some by the upper surface for covering external hollow chamber in liquid nitrogen storage box
The tube seat 6 of test tube, such as 6 tube seats 6, the frozen cell test tube in frozen cell box can be put into tube seat 6, facilitate user
Frozen cell test tube in frozen cell and 21 is picked and placeed, arranged and used, improves Consumer's Experience.The portable ultralow temperature is thin
Born of the same parents, which transport storage device, also includes a handle 5, and the both ends of handle 5 are individually fixed in the two sides of the liquid nitrogen storage box, make this
Device is convenient for carrying, and improves Consumer's Experience.
In this programme, storage access cell is transported using the portable ultralow temperature cell of this patent preferred embodiment
When, freezing storing box in liquid nitrogen container is taken out and is placed in the portable ultralow temperature cell transport storage device 2 minutes, then puts back to liquid nitrogen
In tank, the operation is repeated once daily, totally 30 days, is amounted to 30 times.Contrast groups, will according to existing cell access and Collator Mode
Freezing storing box is placed in room temperature 2 minutes, is then put back in liquid nitrogen container, is repeated once the operation daily, totally 30 days, is amounted to 30 times.It is real
Test result (Fig. 6 and Fig. 7 shown in) and show that two kinds of cells of SMMC 7721 and hybridoma access 30 by above two distinct methods
After secondary, obvious difference in cell amplification rate be present (using double factor variance point after 72 hours in the motility rate of cell and recovery
Analysis, P<0.0001).Accessed repeatedly at 30 times according to the portable ultralow temperature cell transport storage device of present pre-ferred embodiments
Afterwards, the motility rate of freeze-stored cell maintains essentially in 95% or so, and exists according to existing cell access and Collator Mode (at room temperature)
After 30 times access repeatedly, the motility rate of freeze-stored cell drops to 35% or so by 95%.Have sternly to environment temperature in access procedure
Lattice control cell access mode (patent of the present invention), can effectively ensure frozen cell access repeatedly after recovery cell work
Rate, the motility rate after 30 accesses is close to original Cell viability, and the effect of this protection (is not applied by what cell type was influenceed
Double factor variance analysis, P=0.4782).This experiment clearly demonstrate that avoids high temperature from becoming during cell cryopreservation
Change the necessity to cell amplification rate after protection Cell viability and recovery, embody the value place of this patent.
Although the foregoing describing the embodiment of the present invention, it will be appreciated by those of skill in the art that these
It is merely illustrative of, protection scope of the present invention is defined by the appended claims.Those skilled in the art is not carrying on the back
On the premise of principle and essence from the present invention, various changes or modifications can be made to these embodiments, but these are changed
Protection scope of the present invention is each fallen within modification.
Claims (11)
1. a kind of portable ultralow temperature cell transport storage device, it is characterised in that including a shell, liquid is provided with the shell
Nitrogen storage box, the liquid nitrogen storage box include outer layer incubator and internal layer incubator, the outer layer incubator and the shell it
Between form an external hollow chamber, form an inner hollow chamber between the outer layer incubator and internal layer incubator；
The external hollow intracavitary is filled with insulation filling materials, and the inner hollow intracavitary is filled with liquid nitrogen adsorbent, described interior
A groove is provided with layer incubator, a frozen cell box is placed with the groove；
The outer wall of the frozen cell box fits in the inwall of the groove；
The bottom portion of groove is provided with elastic parts, and the elastic parts is used for when being pressurized between nature and compressive state
Switch over；
Each face of the groove is for the good material of heat conductivility or with porous stainless steel web plate.
2. portable ultralow temperature cell transport storage device as claimed in claim 1, it is characterised in that the frozen cell box
It is interior to be provided with some pipe supports for being used to place frozen cell cryopreservation tube.
3. portable ultralow temperature cell transport storage device as claimed in claim 1, it is characterised in that described portable ultralow
Warm cell transport storage device is additionally provided with closure, and the closure is used to seal the groove.
4. portable ultralow temperature cell transport storage device as claimed in claim 1, it is characterised in that the liquid nitrogen storage box
The upper surface of the upper covering external hollow chamber is provided with some tube seats for being used to place frozen cell test tube.
5. portable ultralow temperature cell transport storage device as claimed in claim 1, it is characterised in that also set in the shell
There is control cabinet, the control cabinet is integrated in one with the liquid nitrogen storage box.
6. portable ultralow temperature cell transport storage device as claimed in claim 5, it is characterised in that in the control cabinet also
Provided with alarm module, display module, control module, RAM module and USB interface, the alarm module, the display module, institute
State RAM module and the USB interface electrically connects with the control module.
7. portable ultralow temperature cell transport storage device as claimed in claim 6, it is characterised in that also set in the groove
There are temperature sensor and liquid level sensor, the temperature sensor, the liquid level sensor electrically connect with the control module.
8. portable ultralow temperature cell transport storage device as claimed in claim 6, it is characterised in that on the control cabinet also
Provided with a liquid nitrogen input interface and a liquid nitrogen input pipe, the liquid nitrogen input interface by the liquid nitrogen input pipe with it is described
Inner hollow chamber is connected.
9. portable ultralow temperature cell transport storage device as claimed in claim 1, it is characterised in that the shell is stainless
Outer steel shell, the insulation filling materials are heat-preservation cotton filler.
10. portable ultralow temperature cell transport storage device as claimed in claim 1, it is characterised in that described portable super
Low temperature cell transport storage device also includes a handle, and the both ends of the handle are individually fixed in the both sides of the liquid nitrogen storage box
Face.
11. portable ultralow temperature cell transport storage device as claimed in claim 1, it is characterised in that the frozen cell
Temperature residing for box is -195.8 DEG C~-130 DEG C.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510694875.0A CN105191910B (en) | 2015-10-22 | 2015-10-22 | A kind of portable ultralow temperature cell transport storage device |
Applications Claiming Priority (1)
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|---|---|---|---|
| CN201510694875.0A CN105191910B (en) | 2015-10-22 | 2015-10-22 | A kind of portable ultralow temperature cell transport storage device |
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| CN105191910A CN105191910A (en) | 2015-12-30 |
| CN105191910B true CN105191910B (en) | 2017-11-10 |
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Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106172370A (en) * | 2016-06-27 | 2016-12-07 | 菏泽学院 | A kind of biological sample preserves bottle |
| CN106560246A (en) * | 2016-12-14 | 2017-04-12 | 上海原能细胞医学技术有限公司 | Automatic ejecting type pipe taking machine |
| CN106560408B (en) * | 2016-12-28 | 2018-04-13 | 上海原能细胞医学技术有限公司 | Portable transport liquid nitrogen container |
| CN108935446A (en) * | 2018-08-10 | 2018-12-07 | 陈茶仙 | A kind of automatic household freezer of giant panda sperm |
| CN109644987A (en) * | 2019-01-23 | 2019-04-19 | 南方医科大学南方医院 | It is a kind of for store freezing sample cryopreservation tube device and its implementation |
| CN112027317A (en) * | 2020-08-19 | 2020-12-04 | 浙江省人民医院 | Multifunctional stem cell transport case |
| CN112931485B (en) * | 2021-02-03 | 2022-05-24 | 上海市干细胞技术有限公司 | Portable ultralow-temperature cell transportation and storage device and storage method |
| CN113002995A (en) * | 2021-02-26 | 2021-06-22 | 国家卫生健康委科学技术研究所 | Biological sample operation arrangement platform |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0271085A (en) * | 1988-09-07 | 1990-03-09 | Hitachi Ltd | Liquid nitrogen generator |
| CN202115883U (en) * | 2011-07-01 | 2012-01-18 | 中国人民解放军军事医学科学院卫生装备研究所 | Heat-insulation box for field operations |
| CN202464446U (en) * | 2012-03-07 | 2012-10-03 | 上海安集协康生物技术有限公司 | Thermal box for cold-chain transportation in pharmaceutical field |
| CN202499862U (en) * | 2012-03-28 | 2012-10-24 | 广东温氏食品集团有限公司 | Low-temperature storage device applied to large-scale animal cell culture |
| CN104764278A (en) * | 2015-04-22 | 2015-07-08 | 天津商业大学 | Vacuum thermal insulation house body used for ultralow temperature refrigeration house |
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Effective date of registration: 20200117 Address after: 200120 Room 102, floor 1, building 4, no.1227, zhangheng road and no.1118, Halley Road, China (Shanghai) pilot Free Trade Zone, Pudong New Area, Shanghai Patentee after: Shanghai primary cell biological low temperature Equipment Co Ltd Address before: 201203 Shanghai Free Trade Zone in Pudong New Area Cailun Road, room 816 No. 780 Co-patentee before: BEIJING ORIGINCELL MEDICAL RESEARCH INSTITUTE CO., LTD. Patentee before: SHANGHAI ORIGINCELL MEDICAL TECHNOLOGY CO., LTD. Co-patentee before: ORIGINCELL TECHNOLOGY GROUP CO., LTD. |