CN201752216U - Program temperature reduction box - Google Patents
Program temperature reduction box Download PDFInfo
- Publication number
- CN201752216U CN201752216U CN2010202158159U CN201020215815U CN201752216U CN 201752216 U CN201752216 U CN 201752216U CN 2010202158159 U CN2010202158159 U CN 2010202158159U CN 201020215815 U CN201020215815 U CN 201020215815U CN 201752216 U CN201752216 U CN 201752216U
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- cooling box
- main body
- cover
- box main
- programmed cooling
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Abstract
The utility model provides a program temperature reduction box which comprises a temperature reduction box main body, a heat-preservation cover, a top cover and a bottom cover. The upper end of the temperature reduction box main body is fixed with the heat-preservation cover in a matching manner, and the bottom part is fixed with the bottom cover in a matching manner; the heat-preservation cover which adopts a dual-layer structure is fixed with the top cover in a connecting manner, and heat-preservation materials are filled at the hollow position. The temperature reduction box main body adopts the dual-layer structure, the heat-preservation materials are filled in a sandwich layer, and a plurality of freezing pipe holes are arranged inside. The provided program temperature reduction box is low in price, is simple and convenient for operation, and has constant temperature reduction speed.
Description
Technical field
The utility model relates to a kind of container, particularly a kind of programmed cooling box that is used for test tube cooling usefulness.
Background technology
Slowly freezing during freeze-stored cell.Because cell is direct when freezing under not adding any protectant situation, the inside and outside moisture of cell all can very fast formation ice crystal, and the formation of ice crystal will cause a series of bad reaction.At first cell dehydration increases local electrolyte concentration, partially protein sex change owing to above-mentioned factor, cause the disorder of cell interior space structure, the sex change of protein, enzyme on the formation of ice crystal and the cell membrane system in the cell, the damage that causes lysosome membrane makes lyase discharge the destruction of causing cell inner structure composition, and mitochondrial swelling, afunction also cause the obstacle of cellular energy metabolism.The change that causes the after birth permeability easily takes place to destroy, makes the cellular content forfeiture in the lipoid protein complexes on the after birth in freezing.Cell subject to damage part when the cell nuclear dna also is freezing.Form morely as ice crystal in the cell, with the reduction of cryogenic temperature, the ice crystal volumetric expansion causes the steric configuration of DNA that irreversible damaging variation takes place, and causes the death of cell.
Slowly freezing during freeze-stored cell, programmed cooling is to improve the survival of cell.Present domestic common practice is to adopt the programmed cooling instrument and adopt import procedure cooling box.Employing programmed cooling instrument costs an arm and a leg, complex operation.Adopt import procedure cooling box to need each isopropyl alcohol that adds, and each addition all can cause the change of rate of temperature fall when inconsistent.
The utility model content
At the defective of above-mentioned prior art, the purpose of this utility model provides a kind of cheap, easy and simple to handle, programmed cooling box that rate of temperature fall is constant.
A kind of programmed cooling box, comprise cooling box main body, insulation cover, top cover and bottom, described cooling box main body upper end is matched fixing with described insulation cover, the bottom is matched fixing with described bottom, described insulation cover and described top cover are connected and fixed, and described insulation cover is a double-decker, the hollow position fill insulant material, described cooling box main body is a double-decker, the interlayer fill insulant material, and inside is provided with several frozen pores.
Programmed cooling box of the present utility model, cylindric, the oval column of being shaped as of wherein said cooling box main body, conical column, stairstepping column, square, triangle, pentagon, hexagon, polygon.
Programmed cooling box of the present utility model, being shaped as of wherein said frozen pore is cylindrical, oval, conical, stairstepping.
Programmed cooling box of the present utility model, the quantity of wherein said frozen pore are 1～50, and pore size is 1～100mm, and the degree of depth in hole is 1～200mm.
Programmed cooling box of the present utility model, wherein said cooling box main body upper end and bottom adopt helicitic texture to match with described insulation cover and described bottom respectively, and described insulation cover adopts screw thread to be connected with described top cover.
Programmed cooling box of the present utility model scribbles 704 low temperature resistant silica gel on the external screw thread of wherein said top cover and described bottom.
Programmed cooling box of the present utility model, wherein said cooling box main body, described insulation cover, described top cover and described bottom adopt the polythene PE material to make.
Programmed cooling box of the present utility model, wherein said insulation material are medical absorbent cotton.
Because only programmed cooling box of the present utility model need be put into refrigerating chamber promptly can carry out the constant cooling of rate of temperature fall, therefore easy and simple to handle, and cost of manufacture is lower, and cheap.
Description of drawings
Fig. 1 is that the master of the utility model programmed cooling box looks cutaway view;
Fig. 2 is the vertical view of the cooling box main body of the utility model programmed cooling box.
Embodiment
Be elaborated below in conjunction with the embodiment of accompanying drawing to the utility model programmed cooling box.
Referring to Fig. 1, programmed cooling box of the present utility model adopts low temperature resistant polythene PE material and medical absorbent cotton to make, comprise cooling box main body 1, insulation cover 2, top cover 3, bottom 4, cooling box main body 1 is columned double-decker, interlayer fill insulant material 7, insulation material is a medical absorbent cotton, and inside is provided with cylindrical frozen pore 6, can place 7 frozen pipes of 1.0-2.0ml.Cooling box main body 1 upper end adopts external thread structure to match with insulation cover 2, insulation cover 2 is all double-decker, hollow position fill insulant material 5, this insulation material also is a medical absorbent cotton, insulation cover 2 adopts screw thread to be connected with top cover 3, scribble 704 low temperature resistant silica gel on the external screw thread of top cover 3, in case top cover is loosening.Cooling box main body 1 bottom has internal thread to match with the external screw thread of bottom 4, scribbles 704 low temperature resistant silica gel on the external screw thread of bottom 4, and bottom is tightened the back, prevented to become flexible.
Programmed cooling box of the present utility model has been by having filled insulation material, having guaranteed to carry out cell cryopreservation when experiment, frozen pipe is put into the programmed cooling box after, when the programmed cooling box was put into-70 ℃ of refrigerators, the temperature of frozen pipe can be kept 1 ℃/minute rate of temperature fall.
And the utility model programmed cooling box is compared with the programmed cooling instrument: price be its 1/60, and the operation easier than it; Compare with import procedure cooling box: price be its 1/3, and operation is easier than it, rate of temperature fall is than its constant unanimity.Show by the experiment of a large amount of cell cryopreservation: remarkable advantages such as programmed cooling box of the present utility model is easy and simple to handle, programmed cooling constant rate, cell cryopreservation are effective.
The shape of the cooling box main body 1 of programmed cooling box of the present utility model except be cylindric, can also be oval column, conical column, stairstepping column, square, triangle, pentagon, hexagon, polygon; The shape of frozen pore 6 can also be shapes such as ellipse, taper shape, stairstepping except cylindrical, the quantity of frozen pore 6 is 1～50; Pore size is 1～100mm; The degree of depth in hole is 1～200mm.
Above embodiment is described preferred implementation of the present utility model; be not that scope of the present utility model is limited; under the prerequisite that does not break away from the utility model design spirit; various distortion and improvement that the common engineers and technicians in this area make the technical solution of the utility model all should fall in the definite protection domain of claims of the present utility model.
Claims (8)
1. programmed cooling box, comprise cooling box main body (1), insulation cover (2), top cover (3) and bottom (4), it is characterized in that, described cooling box main body (1) upper end is matched fixing with described insulation cover (2), the bottom is matched fixing with described bottom (4), described insulation cover (2) is connected and fixed with described top cover (3), described insulation cover (2) is a double-decker, hollow position fill insulant material (5), described cooling box main body (1) is a double-decker, interlayer fill insulant material (7), inside are provided with several frozen pores (6).
2. programmed cooling box according to claim 1 is characterized in that, described cooling box main body (1) be shaped as cylindric or oval column or conical column or stairstepping column or polygon.
3. programmed cooling box according to claim 2 is characterized in that, described frozen pore (6) be shaped as cylindrical oval or conical or stairstepping.
4. programmed cooling box according to claim 3 is characterized in that, the quantity of described frozen pore (6) is 1～50, and pore size is 1～100mm, and the degree of depth in hole is 1～200mm.
5. programmed cooling box according to claim 4, it is characterized in that, described cooling box main body (1) upper end and bottom adopt helicitic texture to match with described insulation cover (2) and described bottom (4) respectively, and described insulation cover (2) adopts screw thread to be connected with described top cover (3).
6. programmed cooling box according to claim 5 is characterized in that, scribbles 704 low temperature resistant silica gel on the external screw thread of described top cover (3) and described bottom (4).
7. programmed cooling box according to claim 6 is characterized in that, described cooling box main body (1), described insulation cover (2), described top cover (3) and described bottom (4) adopt the polythene PE material to make.
8. programmed cooling box according to claim 7 is characterized in that, described insulation material (5) is a medical absorbent cotton.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010202158159U CN201752216U (en) | 2010-06-04 | 2010-06-04 | Program temperature reduction box |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010202158159U CN201752216U (en) | 2010-06-04 | 2010-06-04 | Program temperature reduction box |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201752216U true CN201752216U (en) | 2011-03-02 |
Family
ID=43619947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010202158159U Expired - Fee Related CN201752216U (en) | 2010-06-04 | 2010-06-04 | Program temperature reduction box |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201752216U (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102246743A (en) * | 2011-04-20 | 2011-11-23 | 中国人民解放军第三军医大学 | Biological tissue cryopreservation device |
| CN103202286A (en) * | 2013-04-11 | 2013-07-17 | 天津开发区合普工贸有限公司 | Electronic program-controlled const-speed cooling and freezing device |
| CN103704199A (en) * | 2013-09-30 | 2014-04-09 | 杭州柏恒科技有限公司 | Cell freezing box |
| CN103988835A (en) * | 2014-03-12 | 2014-08-20 | 杭州科默斯科技有限公司 | Cell freezing box |
| CN107136052A (en) * | 2017-07-03 | 2017-09-08 | 上海理工大学 | A kind of medical speed governing heat sink |
| CN107318827A (en) * | 2017-07-03 | 2017-11-07 | 上海理工大学 | A kind of medical speed governing heat sink with communication function |
| CN110122476A (en) * | 2019-05-28 | 2019-08-16 | 三明学院 | A kind of cell cryopreservation box |
| CN110169418A (en) * | 2019-05-27 | 2019-08-27 | 遵义医学院附属医院 | A kind of sperm storage device for reproductive medicine |
| CN111607561A (en) * | 2020-05-14 | 2020-09-01 | 北京唐颐惠康生物医学技术有限公司 | Method for constructing large-scale, high-throughput and high-safety stem cell bank |
| CN112021305A (en) * | 2020-09-29 | 2020-12-04 | 上海斗宿生物科技服务有限公司 | Cell preparation procedure cooling and heat insulation box |
-
2010
- 2010-06-04 CN CN2010202158159U patent/CN201752216U/en not_active Expired - Fee Related
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102246743A (en) * | 2011-04-20 | 2011-11-23 | 中国人民解放军第三军医大学 | Biological tissue cryopreservation device |
| CN103202286A (en) * | 2013-04-11 | 2013-07-17 | 天津开发区合普工贸有限公司 | Electronic program-controlled const-speed cooling and freezing device |
| CN103202286B (en) * | 2013-04-11 | 2015-09-02 | 天津开发区合普工贸有限公司 | Electronic program controls at the uniform velocity to lower the temperature freezing plant |
| CN103704199A (en) * | 2013-09-30 | 2014-04-09 | 杭州柏恒科技有限公司 | Cell freezing box |
| CN103704199B (en) * | 2013-09-30 | 2015-07-22 | 杭州柏恒科技有限公司 | Cell freezing box |
| CN103988835A (en) * | 2014-03-12 | 2014-08-20 | 杭州科默斯科技有限公司 | Cell freezing box |
| CN103988835B (en) * | 2014-03-12 | 2015-12-09 | 杭州科默斯科技有限公司 | A kind of cell freezing box |
| CN107318827A (en) * | 2017-07-03 | 2017-11-07 | 上海理工大学 | A kind of medical speed governing heat sink with communication function |
| CN107136052A (en) * | 2017-07-03 | 2017-09-08 | 上海理工大学 | A kind of medical speed governing heat sink |
| CN107136052B (en) * | 2017-07-03 | 2020-11-03 | 上海理工大学 | Medical speed-regulating and temperature-reducing device |
| CN110169418A (en) * | 2019-05-27 | 2019-08-27 | 遵义医学院附属医院 | A kind of sperm storage device for reproductive medicine |
| CN110169418B (en) * | 2019-05-27 | 2021-08-13 | 遵义医学院附属医院 | Sperm storage device for reproductive medicine |
| CN110122476A (en) * | 2019-05-28 | 2019-08-16 | 三明学院 | A kind of cell cryopreservation box |
| CN111607561A (en) * | 2020-05-14 | 2020-09-01 | 北京唐颐惠康生物医学技术有限公司 | Method for constructing large-scale, high-throughput and high-safety stem cell bank |
| CN111607561B (en) * | 2020-05-14 | 2023-08-11 | 北京唐颐惠康生物医学技术有限公司 | Construction method of large-scale, high-flux and high-safety stem cell library |
| CN112021305A (en) * | 2020-09-29 | 2020-12-04 | 上海斗宿生物科技服务有限公司 | Cell preparation procedure cooling and heat insulation box |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110302 Termination date: 20180604 |