CN209628475U - A kind of small-sized biological sample low temperature storage device - Google Patents
A kind of small-sized biological sample low temperature storage device Download PDFInfo
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- CN209628475U CN209628475U CN201821904156.2U CN201821904156U CN209628475U CN 209628475 U CN209628475 U CN 209628475U CN 201821904156 U CN201821904156 U CN 201821904156U CN 209628475 U CN209628475 U CN 209628475U
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- China
- Prior art keywords
- small
- biological sample
- box
- low temperature
- storage device
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- 239000012472 biological sample Substances 0.000 title claims abstract description 49
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 48
- 239000000523 sample Substances 0.000 claims abstract description 30
- 239000007788 liquid Substances 0.000 claims abstract description 24
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 24
- 239000000463 material Substances 0.000 claims abstract description 17
- 239000000945 filler Substances 0.000 claims abstract description 9
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 6
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 4
- 229910052782 aluminium Inorganic materials 0.000 claims description 4
- 239000004033 plastic Substances 0.000 claims description 4
- 229910052742 iron Inorganic materials 0.000 claims description 3
- 230000002085 persistent effect Effects 0.000 abstract description 8
- 238000004321 preservation Methods 0.000 abstract description 4
- 238000002474 experimental method Methods 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 238000005138 cryopreservation Methods 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000002984 plastic foam Substances 0.000 description 2
- 230000006641 stabilisation Effects 0.000 description 2
- 238000011105 stabilization Methods 0.000 description 2
- 241000254154 Sitophilus zeamais Species 0.000 description 1
- 230000001186 cumulative effect Effects 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000013536 elastomeric material Substances 0.000 description 1
- 238000002309 gasification Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
Landscapes
- Sampling And Sample Adjustment (AREA)
Abstract
The utility model discloses a kind of small-sized biological sample low temperature storage devices, belong to sample preservation technical field.Including outter box and inner box, the inner box is located at the inside of outter box, and thermal resistance material layer is filled between the inner box and the outter box；Further include liquid nitrogen hopper and filler cap in the small-sized biological sample low temperature storage device, opens up air hole on the filler cap；The outter box box cover opens up sample cell jack one and through-hole one, and the inner box box cover opens up sample cell jack two and through-hole two, and the liquid nitrogen hopper is through the through-hole one and the through-hole two and extends in the inner box.Aiming at the problem that preservation for a long time when existing low temperature storage device cannot achieve the persistent collection of small-sized biological sample, the utility model provides a kind of small-sized biological sample low temperature storage device, it can keep the long-time low-temperature condition of small-sized biological sample during persistent collection small-sized biological sample.
Description
Technical field
The utility model belongs to sample preservation technology field, specifically, being related to a kind of small-sized biological sample cryo-conservation
Device.
Background technique
Small-sized biological sample (such as feeler of sitophilus zea-mais) is collected vulnerable to temperature interference at room temperature, and is lacked suitable low
Warm save set can cause small-sized biological sample to be easy to happen degradation, denaturation etc., when especially collecting small in vitro biological sample
Persistent collection is needed, it is very unfavorable that sample is exposed to close in the environment of room temperature to the essence for going back raw sample for a long time.For
The problems such as collecting the loss of small-sized biological sample bring, degradation for a long time at normal temperature is solved, there is also low temperature the prior art
Save set, such as Patent No. 201520909411.2, the utility model of entitled " a kind of test specimen low temperature storage device "
Patent discloses a kind of test specimen low temperature storage device, is equipped with whole insulating layer in cabinet, rises between sample and the external world
To heat-insulated effect, cabinet inner thermal insulating layer is equipped with the heat-preserving cover plate on the cover plate edge mutually embedding with heat preservation cover slot, sampling operation knot
After beam covers heat-preserving cover plate, it is completely in specimen material and liquid nitrogen in insulating layer, can further extends material soaking time；But
It is the persistent collection that this low temperature storage device is not suitable for great quantity of small biological sample in laboratory, for small-sized biological sample
Need to be put into same small-sized biological sample repeatedly in (especially small in vitro biological sample) same sample pipe, the cumulative time is up to
The collection work that could complete small-sized biological sample for one or two hour, during which needs operator frequently to open low temperature storage device
Outer cover simultaneously takes out sample storage tube, according to then appearance when being repeatedly opened low temperature storage device outer cover of above-mentioned Patent equipment
A large amount of liquid nitrogen loss, and supplement liquid nitrogen and low temperature is maintained also to need provision for disengagement, this can seriously affect small-sized biological sample in laboratory
The collection efficiency of product, while structure is complicated for most of low temperature storage devices, this is because entire low temperature storage device is in order to guarantee
Good complete seal need to be arranged individual (power supply) cooling system and protect come the super-long-term of sample when meeting long-distance transport
It deposits.
Utility model content
1, it to solve the problems, such as
What is saved for a long time when cannot achieve the persistent collection of small-sized biological sample for existing low temperature storage device asks
Topic, the utility model provide a kind of small-sized biological sample low temperature storage device, it can be in persistent collection small-sized biological sample
The long-time low-temperature condition of small-sized biological sample is kept in the process.
2, technical solution
To solve the above problems, the utility model adopts the following technical scheme.
A kind of small-sized biological sample low temperature storage device, including outter box and inner box, the inner box are located at outter box
Inside, between the inner box and the outter box fill thermal resistance material layer；
It further include liquid nitrogen hopper and filler cap in the small-sized biological sample low temperature storage device, on the filler cap
Open up air hole；
The outter box box cover opens up sample cell jack one and through-hole one,
The inner box box cover opens up sample cell jack two and through-hole two,
The liquid nitrogen hopper is through the through-hole one and the through-hole two and extends in the inner box.
Preferably, the hollow out collet for fixing sample cell is set in the jack two.
Preferably, clump weight is arranged in the bottom of the outter box.
Preferably, it is snapped connection between the outter box box cover and the outter box.
Preferably, the outter box is cube structure.
Preferably, the outter box is made of plastic material；The clump weight is made of iron material.
Preferably, the inner box is made of aluminum material；The inner box with a thickness of 1mm-2mm.
Preferably, a length of 120mm of the inner box, width 80mm, high position 35mm.
Preferably, the diameter of the jack one and the jack two is 11mm-12mm.
Preferably, the length of the hollow out collet is 32mm-34mm, width 11mm-12mm.
3, beneficial effect
Compared with the prior art, the utility model has the following beneficial effects:
(1) low temperature storage device in the utility model, on the one hand without opening outter box box cover and inner box box cover
Being replenished in time to keep consecutive low temperature environment for liquid nitrogen is realized, since the small-sized biological sample low temperature storage device of the application is main
Applied to experiment indoor environment, liquid nitrogen convenient can be obtained, and on the other hand meet the collection demand of small-sized biological sample, without frequency
Numerous opening outter box box cover and inner box box cover are realized the persistent collection of small-sized biological sample, can be guaranteed in longer time
The consistency of most individuals, reduces the error rate of experiment in same sample pipe；
(2) in the utility model hollow out collet setting, fixed sample cell can be supported, avoid falling when sample cell is heavier
Into in inner box；
(3) in the utility model clump weight setting, reduce the influence artificially collided, play stabilization；
(4) using snapping connection between the utility model China and foreign countries box cover and outter box, one side is easy to disassemble, another
The leakproofness of whole device can be improved in aspect.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model.
In figure: 1- outter box, 2- inner box, 3- thermal resistance material layer, 4- liquid nitrogen hopper, 5- filler cap, 6- outter box
Box cover, 7- jack one, 8- through-hole one, 9- inner box box cover, 10- jack two, 11- through-hole two, 12- hollow out collet, 13- counterweight
Block.
Specific embodiment
The utility model is further described below below with reference to specific utility model.
Embodiment 1
As shown in Figure 1, the small-sized biological sample low temperature storage device of the present embodiment, including outter box 1 and inner box 2, institute
The inside that inner box 2 is located at outter box 1 is stated, thermal resistance material layer 3 is filled between the inner box 2 and the outter box 1；
It further include liquid nitrogen hopper 4 and filler cap 5, the filler cap in the small-sized biological sample low temperature storage device
Air hole is opened up on 5, the diameter of air hole can be set within the scope of 4mm-5mm；
The outter box box cover 6 opens up sample cell jack 1 and through-hole 1,
The inner box box cover 9 opens up sample cell jack 2 10 and through-hole 2 11,
The liquid nitrogen hopper 4 is through the through-hole 1 and the through-hole 2 11 and extends in the inner box 2；
Jack 1 and jack 2 10 are corresponding, and through-hole 1 and through-hole 2 11 are also corresponding, it is corresponding setting ensure sample cell or
Positioning accuracy when liquid nitrogen hopper 4 is inserted into；
In the present embodiment, first liquid nitrogen is entered in inner box 2 by liquid nitrogen hopper 4 when use, then by sample
Pipe is placed through jack 1 and corresponding jack 2 10 also enters in inner box 2, and the lower submerged of sample cell is in inner box 2
It is cooled off in interior liquid nitrogen；The low temperature storage device of the application, on the one hand without opening outter box box cover 6 and inner box box cover
9, being replenished in time to keep consecutive low temperature environment for liquid nitrogen can be realized, since the small-sized biological sample cryo-conservation of the application fills
It sets and is mainly used in experiment indoor environment, liquid nitrogen convenient can obtain, on the other hand meet the collection demand of small-sized biological sample,
Without frequently opening outter box box cover 6 and inner box box cover 9, the persistent collection of small-sized biological sample is realized, in longer time
The consistency that can guarantee in same sample pipe most individuals, reduce the error rate of experiment, furthermore the setting of air hole, can be to prevent
Only cause the air pressure of inner box 2 excessive when liquid nitrogen gasification.
Embodiment 2
The small-sized biological sample low temperature storage device of the present embodiment, on the basis of embodiment 1,
As shown in Figure 1, the hollow out collet 12 for fixing sample cell is arranged in the jack 2 10；Under normal circumstances, it engraves
The length of empty collet 12 is less than the length of sample cell；
The setting of hollow out collet 12 can support fixed sample cell, avoid being fallen when sample cell is heavier into inner box 2
It is interior.
Embodiment 3
The small-sized biological sample low temperature storage device of the present embodiment, on the basis of embodiment 1 or 2,
As shown in Figure 1, clump weight 13 is arranged in the bottom of the outter box 1.
The setting of clump weight 13 reduces the influence artificially collided, plays stabilization.
Embodiment 4
The small-sized biological sample low temperature storage device of the present embodiment, on the basis of any one embodiment of embodiment 1-3,
As shown in Figure 1, being snapped connection between the outter box box cover 6 and the outter box 1.
Using snapping connection between outter box box cover 6 and outter box 1, one side is easy to disassemble, on the other hand can be improved
The leakproofness of whole device.
Embodiment 5
The small-sized biological sample low temperature storage device of the present embodiment, on the basis of any one embodiment of embodiment 1-4,
As shown in Figure 1, the outter box 1 is cube structure；The outter box 1 is made of plastic material, especially
When thermal resistance material layer 3 is using plastic foam elastomeric material, the drop resistant performance of whole device can be improved；The clump weight 13 is adopted
It is made of iron material；
The inner box 2 is made of aluminum material, and the ductility of inner box can be improved, reduce the liquid nitrogen pair of ultralow temperature
Inner box 2 generates destructiveness；The inner box 2 with a thickness of 1mm-2mm.
Outter box 1 can be using conventional plastic storage box, and inner box 2 can be using conventional aluminum lunch box, then
Plastic foam is filled up between outter box 1 and inner box 2, it is convenient that raw material obtain, low in cost.
Embodiment 7
The small-sized biological sample low temperature storage device of the present embodiment, on the basis of any one embodiment of embodiment 1-6,
As shown in Figure 1, a length of 120mm of the inner box 2, width 80mm, high position 35mm；The volume of inner box 2 is arranged,
On the one hand on the other hand both save the cost can obtain preferably cooling and hold time, liquid nitrogen can keep inner box 2 after being added
Low temperature at least one it is more than half an hour；
The diameter of the jack 1 and the jack 2 10 is 11mm-12mm；Since common sample cell is 2ml appearance
Amount, diameter is generally fixed value, is not in liquid nitrogen from gap in order to ensure sample cell is inserted into after jack 1 and jack 2 10
Middle evolution, it usually needs the diameter of jack 1 and socket 2 10 is close with the diameter of sample cell as far as possible；
The length of the hollow out collet 12 is 32mm-34mm, width 11mm-12mm.
The above content is be described in further detail to the utility model in conjunction with specific embodiment, and it cannot be said that this is practical
Novel specific implementation is only limited to these instructions, for the utility model person of an ordinary skill in the technical field, In
Under the premise of the design for not departing from the utility model, several simple deduction or replace can also be made, all shall be regarded as belonging to
The protection scope that claims that the utility model is submitted determine.
Claims (10)
1. a kind of small-sized biological sample low temperature storage device, including outter box (1) and inner box (2), the inner box (2) are located at
Thermal resistance material layer (3) are filled between the inner box (2) and the outter box (1) in the inside of outter box (1)；
It is characterized by:
It further include liquid nitrogen hopper (4) and filler cap (5), the filler cap in the small-sized biological sample low temperature storage device
(5) air hole is opened up on；
The outter box box cover (6) opens up sample cell jack one (7) and through-hole one (8),
The inner box box cover (9) opens up sample cell jack two (10) and through-hole two (11),
The liquid nitrogen hopper (4) is through the through-hole one (8) and the through-hole two (11) and extends to the inner box (2)
It is interior.
2. small-sized biological sample low temperature storage device according to claim 1, it is characterised in that: in the jack two (10)
Hollow out collet (12) for fixing sample cell is set.
3. small-sized biological sample low temperature storage device according to claim 1, it is characterised in that: the outter box (1)
Clump weight (13) are arranged in bottom.
4. small-sized biological sample low temperature storage device according to claim 1, it is characterised in that: the outter box box cover
(6) it is snapped connection between the outter box (1).
5. small-sized biological sample low temperature storage device according to claim 1, it is characterised in that: the outter box (1) is
Cube structure.
6. small-sized biological sample low temperature storage device according to claim 3, it is characterised in that: the outter box (1) is adopted
It is made of plastic material；The clump weight (13) is made of iron material.
7. small-sized biological sample low temperature storage device described in -5 any one according to claim 1, it is characterised in that: in described
Box body (2) is made of aluminum material；The inner box (2) with a thickness of 1mm-2mm.
8. small-sized biological sample low temperature storage device according to claim 7, it is characterised in that: the inner box (2)
A length of 120mm, width 80mm, high position 35mm.
9. small-sized biological sample low temperature storage device described in -5 any one according to claim 1, it is characterised in that: described to insert
The diameter of hole one (7) and the jack two (10) is 11mm-12mm.
10. small-sized biological sample low temperature storage device according to claim 2, it is characterised in that: the hollow out collet
(12) length is 32mm-34mm, width 11mm-12mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821904156.2U CN209628475U (en) | 2018-11-19 | 2018-11-19 | A kind of small-sized biological sample low temperature storage device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821904156.2U CN209628475U (en) | 2018-11-19 | 2018-11-19 | A kind of small-sized biological sample low temperature storage device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209628475U true CN209628475U (en) | 2019-11-15 |
Family
ID=68472231
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821904156.2U Expired - Fee Related CN209628475U (en) | 2018-11-19 | 2018-11-19 | A kind of small-sized biological sample low temperature storage device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209628475U (en) |
-
2018
- 2018-11-19 CN CN201821904156.2U patent/CN209628475U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20191115 Termination date: 20201119 |